A mixing device for chemiluminescence immunoassay

Abstract

The utility model belongs to chemical detection technical field especially for a kind of mixing device for chemiluminescence immunoassay, including mechanical arm, the lateral slide of mechanical arm is equipped with transverse drive arm, the side of transverse drive arm is equipped with longitudinal drive arm. This kind of mixing device for chemiluminescence immunoassay, by sliding connecting block on integrated plate vertical sliding drive gripper assembly vertical movement, sample and reagent are added into reaction cup, after reaction cup is grabbed by gripper assembly, vibration motor starts, drives vibration mounting seat and reaction cup vibration, rubber seat mainly provides a flexible connection, when gripper assembly vibration, it can provide a larger vibration amplitude to reach the mixing effect of sample and reagent in reaction cup. Such design, by the integration of gripper assembly and vibration motor, complete mixing action in the scheduling process of reaction cup, can simplify work flow, simultaneously, independent mixing mechanism is saved, and cost is saved.

Description

Technical Field

[0001] This utility model relates to the field of chemical detection technology, specifically a mixing device for chemiluminescence immunoassay. Background Technology

[0002] Chemiluminescence immunoassay is a widely used clinical testing technique that combines highly sensitive chemiluminescence assay with highly specific immunoreaction to detect and analyze various antigens, haptens, antibodies, hormones, enzymes, fatty acids, vitamins, and drugs.

[0003] In chemiluminescence immunoassay, the reagent sample needs to be mixed. Current technology typically uses a separate mixing mechanism to pick up the reaction vessel, add the sample and reagents, mix, and then a gripper moves the vessel to the next step in the process. Therefore, the separate mixing mechanism in existing solutions is not only structurally complex but also adds more steps, increasing experimental costs. Utility Model Content

[0004] To address the shortcomings of existing technologies, this invention provides a mixing device for chemiluminescent immunoassay, which solves the current problems.

[0005] To achieve the above objectives, this utility model provides the following technical solution: a mixing device for chemiluminescence immunoassay, comprising a robotic arm, a transverse drive arm slidably mounted on the outer side of the robotic arm, a longitudinal drive arm slidably mounted on the side of the transverse drive arm, a gripper module mounted on the side of the longitudinal drive arm, the gripper module comprising an integrated plate fixedly mounted on the side of the longitudinal drive arm, a sliding connecting block slidably mounted on the front of the integrated plate, a gripper fixing plate fixedly mounted on the front of the sliding connecting block, one end of a rubber seat fixedly mounted on the surface of the gripper fixing plate, a vibration mounting base fixedly mounted on the other end of the rubber seat, a vibration motor fixedly mounted on the inner side of the vibration mounting base, a gripper assembly and a guide block fixedly mounted on the outer side of the vibration mounting base, a reaction cup disposed on the side of the gripper assembly, and the gripper assembly capable of gripping the reaction cup.

[0006] As a preferred technical solution of this utility model, the gripper assembly includes a connecting seat fixedly installed on the outside of the vibration mounting base, a reflective optical coupler fixedly installed on the back of the connecting seat, and a left gripper and a right gripper rotatably installed on the bottom of the connecting seat via a rotating shaft, with a tension spring fixedly installed between the left gripper and the right gripper.

[0007] As a preferred technical solution of this utility model, the front side of the integrated plate is fixedly installed with parallel distributed gripper guide shafts and vibration limiting shafts, and the gripper guide shafts and vibration limiting shafts are slidably inserted and installed on the outside of the guide block, and the gripper guide shafts are shorter than the vibration limiting shafts.

[0008] As a preferred embodiment of this utility model, a linear guide rail is fixedly installed on the front side of the integrated plate, and the sliding connecting block is slidably installed on the outside of the linear guide rail.

[0009] As a preferred embodiment of this utility model, a vertical motion motor is fixedly installed on the back of the integrated plate, and two drive columns are rotatably installed on the front of the integrated plate. The output end of the vertical motion motor passes through the integrated plate and is fixedly connected to one of the drive columns. A vertical motion belt is sleeved on the outer side of the two drive columns, and the side of the sliding connecting block is fixedly connected to the side of the vertical motion belt.

[0010] As a preferred embodiment of this utility model, the motion trajectory of the sliding connecting block is parallel to the axial direction of the gripper guide shaft and the vibration limiting shaft, respectively.

[0011] Compared with the prior art, the present invention provides a mixing device for chemiluminescent immunoassay, which has the following advantages:

[0012] 1. This mixing device for chemiluminescence immunoassay utilizes a sliding connecting block that slides vertically on an integrated plate, driving a gripper assembly to move vertically. Samples and reagents are added to a reaction cup. After the gripper assembly grasps the reaction cup, a vibration motor is activated, causing the vibration mounting base and the reaction cup to vibrate. The rubber base provides a flexible connection, and the gripper assembly's vibration provides a large amplitude to achieve effective mixing of the sample and reagents within the reaction cup. This design, through the integration of the gripper assembly and the vibration motor, completes the mixing action during the reaction cup's movement, simplifying the workflow and eliminating the need for a separate mixing mechanism, thus reducing costs.

[0013] 2. This mixing device for chemiluminescence immunoassay uses a sliding connecting block that moves vertically on an integrated plate. This movement drives the gripper fixing plate, which in turn drives the guide block. The guide block slides on the surfaces of the gripper guide shaft and the vibration limiting shaft, thus restricting the movement trajectory of the gripper assembly. This allows the reaction cup to move vertically along the gripper guide shaft, improving the stability of the vertical movement of the reaction cup. When the guide block disengages from the gripper guide shaft but not from the vibration limiting shaft, the vibration motor starts, causing the reaction cup to vibrate. This ensures that the reaction cup can vibrate while limiting the vibration, preventing excessive vibration amplitude that could cause reagent spillage. Attached Figure Description

[0014] Figure 1 This is a schematic diagram of the structure of this utility model;

[0015] Figure 2 This is an enlarged structural schematic diagram of the gripper module of this utility model;

[0016] Figure 3 This is an exploded view of the gripper module of this utility model;

[0017] Figure 4 This is a schematic diagram of the structural distribution near the gripper component of this utility model.

[0018] In the diagram: 1. Robotic arm; 2. Lateral drive arm; 3. Longitudinal drive arm; 4. Gripper module; 41. Vertical motion motor; 42. Vertical motion belt; 43. Linear guide rail; 44. Sliding connecting block; 45. Gripper assembly; 451. Connecting seat; 452. Left gripper; 453. Right gripper; 454. Tension spring; 46. Vibration motor; 47. Gripper fixing plate; 48. Rubber seat; 49. Vibration mounting seat; 410. Guide block; 411. Reflective optocoupler; 412. Gripper guide shaft; 413. Vibration limiting shaft; 414. Integrated plate; 415. Drive column; 5. Reaction cup. Detailed Implementation

[0019] The technical solutions of the present utility model will be clearly and completely described below with reference to the accompanying drawings of the embodiments. Obviously, the described embodiments are only some embodiments of the present utility model, and not all embodiments. Based on the embodiments of the present utility model, all other embodiments obtained by those of ordinary skill in the art without creative effort are within the protection scope of the present utility model.

[0020] Example 1

[0021] Please see Figure 1-4 In this embodiment: a mixing device for chemiluminescence immunoassay includes a robotic arm 1, a transverse drive arm 2 slidably mounted on the outer side of the robotic arm 1, a longitudinal drive arm 3 slidably mounted on the side of the transverse drive arm 2, a gripper module 4 mounted on the side of the longitudinal drive arm 3, the gripper module 4 includes an integrated plate 414 fixedly mounted on the side of the longitudinal drive arm 3, a sliding connecting block 44 slidably mounted on the front of the integrated plate 414, a gripper fixing plate 47 fixedly mounted on the front of the sliding connecting block 44, one end of a rubber seat 48 fixedly mounted on the surface of the gripper fixing plate 47, a vibration mounting seat 49 fixedly mounted on the other end of the rubber seat 48, a vibration motor 46 fixedly mounted on the inner side of the vibration mounting seat 49, a gripper assembly 45 and a guide block 410 fixedly mounted on the outer side of the vibration mounting seat 49, a reaction cup 5 is provided on the side of the gripper assembly 45, and the gripper assembly 45 can grip the reaction cup 5;

[0022] In use, the horizontal drive arm 2 drives the vertical drive arm 3 to move laterally, which in turn drives the gripper module 4 to move longitudinally. The sliding connecting block 44 slides vertically on the integrated plate 414, causing the gripper assembly 45 to move vertically. Samples and reagents are added to the reaction cup 5. After the gripper assembly 45 grasps the reaction cup 5, the vibration motor 46 starts, causing the vibration mounting base 49 and the reaction cup 5 to vibrate. The rubber base 48 mainly provides a flexible connection. When the gripper assembly 45 vibrates, it can provide a large vibration amplitude to achieve a mixing effect between the sample and reagents in the reaction cup 5. This design, through the integration of the gripper assembly 45 and the vibration motor 46, completes the mixing action during the scheduling of the reaction cup 5, simplifying the workflow and eliminating the need for a separate mixing mechanism, thus simplifying the mechanism and saving costs.

[0023] In a preferred embodiment, the gripper assembly 45 includes a connecting seat 451 fixedly mounted on the outside of the vibration mounting base 49. A reflective optocoupler 411 is fixedly mounted on the back of the connecting seat 451. A left gripper 452 and a right gripper 453 are rotatably mounted on the bottom of the connecting seat 451 via a rotating shaft. A tension spring 454 is fixedly mounted between the left gripper 452 and the right gripper 453. Through the movement of the transverse drive arm 2 and the longitudinal drive arm 3, the left gripper 452 and the right gripper 453 are moved to the side of the reaction cup 5 and gradually approach the reaction cup 5 until the reaction cup 5 is located between the left gripper 452 and the right gripper 453. During this process, the tension spring 454 is stretched, so that the left gripper 452 and the right gripper 453 clamp the reaction cup 5. The infrared light emitted by the reflective optocoupler 411 can detect whether the gripper assembly 45 has gripped the reaction cup 5.

[0024] In a preferred embodiment, a gripper guide shaft 412 and a vibration limiting shaft 413 are fixedly mounted on the front side of the integrated plate 414, respectively. The gripper guide shaft 412 and the vibration limiting shaft 413 are slidably inserted and installed on the outer side of the guide block 410. The gripper guide shaft 412 is shorter than the vibration limiting shaft 413. The sliding connecting block 44 moves vertically on the integrated plate 414, which can drive the gripper fixing plate 47 to move, thereby driving the guide block 410 to move, so that the guide block 410 is positioned between the gripper guide shaft 412 and the vibration limiting shaft 413. The surface of the moving limiting shaft 413 slides, thereby restricting the movement trajectory of the gripper assembly 45, so that the reaction cup 5 moves vertically along the direction of the gripper guide shaft 412, improving the stability of the vertical movement of the reaction cup 5. When the guide block 410 disengages from the gripper guide shaft 412 but does not disengage from the vibration limiting shaft 413, the vibration motor 46 starts, causing the reaction cup 5 to vibrate. This ensures that the reaction cup 5 can vibrate, and also restricts the vibration of the reaction cup 5, preventing the vibration amplitude from being too large and causing the reagent to spill out.

[0025] Example 2

[0026] Please see Figure 1-4 In this embodiment: a linear guide rail 43 is fixedly installed on the front of the integrated plate 414, and a sliding connecting block 44 is slidably installed on the outside of the linear guide rail 43, which further restricts the vertical movement trajectory of the sliding connecting block 44 and improves the stability of the reaction cup 5 during vertical movement.

[0027] In a preferred embodiment, a vertical motion motor 41 is fixedly mounted on the back of the integrated plate 414, and two drive columns 415 are rotatably mounted on the front of the integrated plate 414. The output end of the vertical motion motor 41 passes through the integrated plate 414 and is fixedly connected to one of the drive columns 415. A vertical motion belt 42 is sleeved on the outer side of the two drive columns 415. The side of the sliding connecting block 44 is fixedly connected to the side of the vertical motion belt 42. The vertical motion motor 41 is a forward and reverse motor. By starting the vertical motion motor 41, the drive column 415 can be driven to rotate, which in turn drives the vertical motion belt 42 to move. The vertical motion belt 42 drives the sliding connecting block 44 to move vertically on the surface of the linear guide rail 43.

[0028] In a preferred embodiment, the motion trajectory of the sliding connecting block 44 is parallel to the axial direction of the gripper guide shaft 412 and the vibration limiting shaft 413, respectively, thereby improving the stability of the vertical movement of the reaction cup 5.

[0029] In this application, the movement of the horizontal drive arm 2 and the vertical drive arm 3 is a technical means that can be achieved under the prior art, and this application does not elaborate on it. A controller is installed on the outside of the robotic arm 1. The controller can control the start and stop of the movement of the vertical motion motor 41, the vibration motor 46, the horizontal drive arm 2 and the vertical drive arm 3.

[0030] Finally, it should be noted that the above are merely preferred embodiments of this utility model and are not intended to limit the utility model. Although the utility model has been described in detail with reference to the foregoing embodiments, those skilled in the art can still modify the technical solutions described in the foregoing embodiments or make equivalent substitutions for some of the technical features. Any modifications, equivalent substitutions, improvements, etc., made within the spirit and principles of this utility model should be included within the protection scope of this utility model.

Claims

1. A mixing device for chemiluminescent immunoassay, comprising a robotic arm (1), wherein a transverse drive arm (2) is slidably mounted on the outer side of the robotic arm (1), and a longitudinal drive arm (3) is slidably mounted on the side of the transverse drive arm (2), characterized in that: A gripper module (4) is installed on the side of the longitudinal drive arm (3). The gripper module (4) includes an integrated plate (414) fixedly installed on the side of the longitudinal drive arm (3). A sliding connecting block (44) is slidably installed on the front of the integrated plate (414). A gripper fixing plate (47) is fixedly installed on the front of the sliding connecting block (44). One end of a rubber seat (48) is fixedly installed on the surface of the gripper fixing plate (47). A vibration mounting seat (49) is fixedly installed on the other end of the rubber seat (48). A vibration motor (46) is fixedly installed on the inner side of the vibration mounting seat (49). A gripper assembly (45) and a guide block (410) are fixedly installed on the outer side of the vibration mounting seat (49). A reaction cup (5) is provided on the side of the gripper assembly (45). The gripper assembly (45) can grip the reaction cup (5).

2. The mixing device for chemiluminescent immunoassay according to claim 1, characterized in that: The gripper assembly (45) also includes a connecting seat (451) fixedly installed on the outside of the vibration mounting base (49). A reflective optocoupler (411) is fixedly installed on the back of the connecting seat (451). A left gripper (452) and a right gripper (453) are rotatably installed on the bottom of the connecting seat (451) via a rotating shaft. A tension spring (454) is fixedly installed between the left gripper (452) and the right gripper (453).

3. The mixing device for chemiluminescent immunoassay according to claim 1, characterized in that: The front side of the integrated plate (414) is fixedly equipped with a gripper guide shaft (412) and a vibration limiting shaft (413) that are distributed in parallel. The gripper guide shaft (412) and the vibration limiting shaft (413) are slidably inserted and installed on the outside of the guide block (410). The gripper guide shaft (412) is shorter than the vibration limiting shaft (413).

4. The mixing device for chemiluminescent immunoassay according to claim 3, characterized in that: A linear guide rail (43) is fixedly installed on the front side of the integrated plate (414), and the sliding connecting block (44) is slidably installed on the outside of the linear guide rail (43).

5. The mixing device for chemiluminescent immunoassay according to claim 4, characterized in that: A vertical motion motor (41) is fixedly installed on the back of the integrated plate (414), and two drive columns (415) are rotatably installed on the front of the integrated plate (414). The output end of the vertical motion motor (41) passes through the integrated plate (414) and is fixedly connected to one of the drive columns (415). A vertical motion belt (42) is sleeved on the outer side of the two drive columns (415), and the side of the sliding connecting block (44) is fixedly connected to the side of the vertical motion belt (42).

6. The mixing device for chemiluminescent immunoassay according to claim 4, characterized in that: The motion trajectory of the sliding connecting block (44) is parallel to the axial direction of the gripper guide shaft (412) and the vibration limiting shaft (413), respectively.

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