A helicobacter pylori detection device based on optical density

Abstract

The utility model relates to the field of helicobacter pylori detection, especially a helicobacter pylori detection device based on optical density, including transmitting light subassembly, casing subassembly, reagent placing subassembly and detection positioning piece, transmitting light subassembly with reagent placing subassembly install in casing subassembly, transmitting light subassembly includes light source and filter piece subassembly, light source installs in casing subassembly, filter piece subassembly rotatably installs in casing subassembly, the functional end of filter piece subassembly is located the just below of light source, reagent placing subassembly rotatably installs in casing subassembly, reagent placing subassembly is located the just below of transmitting light subassembly, casing subassembly detachably installs on detection positioning piece, solve the problem that the sensitivity is low and is easily affected by subjective factor based on dental plaque sample detection helicobacter pylori when the current family self -test.

Description

Technical Field

[0001] This utility model relates to the field of Helicobacter pylori detection, and in particular to a Helicobacter pylori detection device based on optical density. Background Technology

[0002] Helicobacter pylori (Hp) is a pathogenic Gram-negative bacterium that can cause chronic gastritis, peptic ulcers, and even stomach cancer. As early as 1994, the International Agency for Research on Cancer (IARC) classified Hp as a Group 1 carcinogen. Hp is primarily transmitted between humans via oral-oral and fecal-oral routes, can colonize the stomach for extended periods, and is widely distributed throughout the mouth, stomach, and intestines. Approximately 50% of the global population is infected with Hp, posing a significant threat to global health.

[0003] Currently, various detection methods have been developed for the diagnosis and screening of Helicobacter pylori. In recent years, multiple PCR detection studies have detected Helicobacter pylori-specific DNA in dental plaque, indicating that the oral cavity can serve as a temporary ecological niche for Helicobacter pylori, participating in the transmission and reinfection process of the bacteria through the "stomach-oral-stomach" transmission route. In recent years, various Helicobacter pylori oral plaque test strips for home testing have appeared on the market. This detection method is widely used due to its non-invasiveness, convenience, and extremely low sampling threshold.

[0004] However, while current dental plaque test strips on the market are convenient and inexpensive, they primarily rely on visual interpretation of results, making them susceptible to subjective biases and interpretation errors. Furthermore, methods based on visual interpretation are limited by the resolution of human vision, resulting in low sensitivity. Utility Model Content

[0005] To address the aforementioned shortcomings, the purpose of this invention is to propose a Helicobacter pylori detection device based on optical density, thereby solving the problems of low sensitivity and susceptibility to subjective factors in current home self-testing methods that rely on dental plaque samples to detect Helicobacter pylori.

[0006] To achieve this objective, the present invention adopts the following technical solution:

[0007] A Helicobacter pylori detection device based on optical density includes an emitting light component, a housing component, a reagent placement component, and a detection positioning component;

[0008] The light emitting component and the reagent placement component are installed inside the housing component. The light emitting component includes a light source and a filter component. The light source is installed inside the housing component, and the filter component is rotatably installed inside the housing component. The functional end of the filter component is located directly below the light source and is used to filter out light of the desired wavelength.

[0009] The reagent placement assembly is rotatably mounted inside the housing assembly, and is located directly below the light emitting assembly. The reagent placement assembly is used to place sample reagents.

[0010] The housing assembly is detachably mounted on the detection positioning component. The detection positioning component has a first accommodating area and a second accommodating area that are interconnected. The first accommodating area is adapted to the shape of the housing assembly and is used to accommodate the housing assembly. The second accommodating area is used to accommodate the light intensity detection instrument and is located directly below the reagent placement assembly.

[0011] Preferably, the reagent placement assembly includes a first rotating support and a cuvette;

[0012] One end of the first rotating bracket is rotatably mounted to the housing assembly, and the other end of the first rotating bracket is used to detachably mount the colorimetric cup, which is used to hold sample reagents.

[0013] Preferably, the filter assembly includes an adjustment component, a second rotating support, and a filter;

[0014] One end of the second rotating bracket is fixedly mounted with a rotating shaft, which is rotatably mounted on the housing assembly. The end of the rotating shaft is provided with the adjusting component, and the other end of the second rotating bracket is provided with a filter cavity for placing the filter.

[0015] Preferably, the housing assembly includes a supporting housing and an outer cover;

[0016] The light-emitting component and the reagent placement component are respectively mounted on the support housing; the outer cover is detachably mounted on the support housing and covers the light-emitting component and the reagent placement component.

[0017] Furthermore, the support housing is provided with a clearance groove, which is used to provide rotation space for the filter assembly and the reagent placement assembly.

[0018] Preferably, the support housing is provided with a transmission component, which is cylindrical. One end of the transmission component is located directly below the reagent placement assembly, and the other end of the transmission component is connected to the input end of the light intensity detector. The interior of the transmission component is a straight channel.

[0019] Preferably, the detection positioning component has a vertically arranged side plate, the size of which is adapted to the housing assembly;

[0020] The outer side of the rotatable end of the first rotating bracket is racetrack-shaped, and its outward straight edge is flush with the outer side of the housing assembly; when the housing assembly is placed in the first receiving area, the outward straight edge of the rotatable end of the first rotating bracket is in contact with the inner wall of the side plate.

[0021] Preferably, the light-emitting component further includes a switch and a battery;

[0022] The battery is located at the bottom of the housing assembly. The battery, switch and light source are electrically connected. The battery is used to power the light source and the switch is used to control the switching of the light source.

[0023] Preferably, the light intensity detection instrument is a mobile phone with an ambient light sensor and internal light intensity detection software.

[0024] Furthermore, the second accommodating area of ​​the detection positioning component is consistent with the thickness of the mobile phone, and the end of the transmission component contacts the mobile phone and encloses the input end of the ambient light sensor.

[0025] The technical solution provided by this utility model can include the following beneficial effects:

[0026] The detection device includes an emitting light component, a filter component, a reagent placement component, and a light intensity detector. The light from the light source is filtered by the filter component, and light of a specific wavelength passes through the sample reagent. The absorbance is then detected by the light intensity detector. The absorbance value is used to interpret the positive or negative result, improving the sensitivity of Helicobacter pylori detection and avoiding errors caused by subjective judgment. After the sample reagent is placed in the reagent placement component, the position of the light intensity detector is fixed by the detection positioning component to obtain the light intensity, and then the absorbance of the sample reagent is obtained, which is simple and convenient. Attached Figure Description

[0027] Figure 1 This is a structural schematic diagram of one embodiment of the present invention.

[0028] Figure 2 This is an exploded structural diagram of one embodiment of the present invention.

[0029] Figure 3 This is a schematic diagram of the detection positioning component and reagent placement assembly according to one embodiment of the present invention.

[0030] Figure 4 This is a schematic diagram of the structure of a filter assembly according to an embodiment of the present invention.

[0031] Figure 5 This is a structural schematic diagram of one embodiment of the present invention.

[0032] The components include: light emission assembly 1, light source 11, filter assembly 12, adjustment component 121, second rotating bracket 122, filter 123, switch 13, battery 14, housing assembly 2, support housing 21, clearance groove 211, transmission component 212, outer cover 22, reagent placement assembly 3, first rotating bracket 31, colorimetric cup 32, detection positioning component 4, first receiving area 41, side plate 411, second receiving area 42, and light intensity detection instrument 5. Detailed Implementation

[0033] The embodiments of this utility model are described in detail below. Examples of these embodiments are shown in the accompanying drawings, wherein the same or similar reference numerals denote the same or similar elements or elements having the same or similar functions throughout. The embodiments described below with reference to the accompanying drawings are exemplary and are only used to explain this utility model, and should not be construed as limiting this utility model.

[0034] In the description of this utility model, it should be understood that the terms "longitudinal," "lateral," "upper," "lower," "front," "rear," "left," "right," "vertical," "horizontal," "top," "bottom," "inner," and "outer," etc., indicating the orientation or positional relationship, are based on the orientation or positional relationship shown in the accompanying drawings and are only for the convenience of describing this utility model and simplifying the description. They do not indicate or imply that the device or element referred to must have a specific orientation, or be constructed and operated in a specific orientation, and therefore should not be construed as a limitation on this utility model. Furthermore, features defined with "first" and "second" may explicitly or implicitly include one or more of these features, used to distinguish and describe features, without any order or emphasis.

[0035] In the description of this utility model, it should be noted that, unless otherwise explicitly specified and limited, the terms "installation," "connection," and "joining" should be interpreted broadly. For example, they can refer to a fixed connection, a detachable connection, or an integral connection; they can refer to a mechanical connection or an electrical connection; they can refer to a direct connection or an indirect connection through an intermediate medium; and they can refer to the internal connection of two components. Those skilled in the art can understand the specific meaning of the above terms in this utility model based on the specific circumstances.

[0036] like Figures 1 to 5 As shown, a Helicobacter pylori detection device based on optical density includes an emitting light component 1, a housing component 2, a reagent placement component 3, and a detection positioning component 4;

[0037] The light emitting component 1 and the reagent placement component 3 are installed inside the housing component 2. The light emitting component 1 includes a light source 11 and a filter component 12. The light source 11 is installed inside the housing component 2, and the filter component 12 is rotatably installed inside the housing component 2. The functional end of the filter component 12 is located directly below the light source 11 and is used to filter out light of the desired wavelength.

[0038] The reagent placement component 3 is rotatably installed inside the housing component 2. The reagent placement component 3 is located directly below the light emitting component 1. The reagent placement component 3 is used to place sample reagents.

[0039] The housing assembly 2 is detachably mounted on the detection positioning component 4. The detection positioning component 4 has a first accommodating area 41 and a second accommodating area 42 that are interconnected. The first accommodating area 41 is adapted to the shape of the housing assembly 2 and is used to accommodate the housing assembly 2. The second accommodating area 42 is used to accommodate the light intensity detection instrument 5 and is located directly below the reagent placement assembly 3.

[0040] To address the problems existing in the prior art, this utility model proposes a Helicobacter pylori detection device based on optical density, such as... Figure 1 and Figure 2 As shown, the device includes a light emitting component 1, a reagent placement component 3, and a housing component 2. The light emitting component 1 and the reagent placement component 3 are installed inside the housing component 2. The detection end of the light intensity detection instrument 5 is located directly below the reagent placement component 3. The light intensity detection instrument 5 is used to receive and detect the light emitted by the light source 11 and passing through the filter component 12 and the reagent placement component 3. The light source 11, the functional end of the filter assembly 12, the sample reagent, and the light intensity detection instrument 5 are located on the same straight line. The light from the light source 11 is filtered by the filter assembly 12, and light of a specific wavelength passes through the sample reagent. After being absorbed by the sample reagent, the light intensity is received and detected by the light intensity detection instrument 5. Based on the light intensity value detected by the light intensity detection instrument 5, the tester converts it into absorbance and compares it with a known critical value to determine whether the result is positive or negative. Compared with commercially available Helicobacter pylori test strips, the basic principle is to detect the urease produced by Helicobacter pylori in dental plaque, which catalyzes the decomposition of urea, and the change in pH value causes a change in the color of the indicator to achieve the judgment. However, the color of the test strip is easily affected by subjective factors when judged by the naked eye, resulting in low sensitivity. This utility model uses objective values ​​to replace subjective color judgment, which is not easily affected by subjective factors and is not affected by the limits of human visual perception, thus improving sensitivity and solving the problem of low sensitivity and susceptibility to subjective factors in the detection of Helicobacter pylori based on dental plaque samples in current home self-testing.

[0041] Based on the principle of urease produced by Helicobacter pylori in dental plaque catalyzing the decomposition of urea and causing a color change in the indicator, the device uses the following steps: Phenolic red reagent, urea reagent, and physiological saline are prepared in advance. A commercially available interdental brush is used to gently scrape the tooth surface to ensure sufficient adhesion of the dental plaque sample. The sample is then immersed in physiological saline to obtain a dental plaque suspension. Phenolic red reagent and urea reagent are added, and the mixture is allowed to stand for 15-20 minutes to obtain the sample reagent. This sample reagent is placed in the reagent placement component 3, and the light intensity I after absorption by the sample reagent is measured using the light intensity detector 5. Prior to this, the light intensity I0 without the sample reagent is measured. The absorbance A of the sample reagent is calculated using the Lambert-Beer law (A = lg(I0 / I)). Since the sample reagent contains phenolic red reagent, the color of the sample reagent will change depending on the presence or absence of Helicobacter pylori, resulting in different light absorption capabilities, i.e., inconsistent absorbance. By comparing the detected absorbance with a critical value, Helicobacter pylori can be qualitatively detected, and the positivity or positivity of Helicobacter pylori can be determined. In addition, the known threshold is determined by testing different sample reagents with this detection device to obtain absorbance, and then comparing the obtained absorbance values ​​with the results of the clinical urease breath test to establish an ROC curve (recipient operating characteristic curve). During the use of this detection device, the positive or negative result is determined based on whether the absorbance value of each reagent sample is greater than the threshold. When it is greater than the threshold, it is positive; when it is not greater than the threshold, it is negative.

[0042] Specifically, the required wavelength of light is provided by the emitting light component 1 and the filter component 12, providing a basis for measuring light intensity and obtaining absorbance. The filter component 12 is rotatably installed inside the housing component 2, and the filters 123 in the filter component 12 can be replaced or stored as needed, ensuring that the light is of the required wavelength during the measurement process. Simultaneously, the filter component 12 effectively reduces the influence of ambient light on the detection results because other wavelengths that do not match the detection requirements are blocked after the light passes through the filter component 12, ensuring that the light intensity detection instrument 5 only receives and detects light of the required wavelength. The light signal directly related to the change of the sample reagent is measured, which improves the sensitivity of the detection and effectively prevents false positive and false negative results. The reagent placement component 3 is rotatably installed in the housing component 2. The rotation of the reagent placement component 3 facilitates the addition of sample reagent for detection after the light intensity without sample reagent has been detected, which is simple and convenient. The housing component 2 can further reduce the influence of the dark environment on the detection results and is adapted to the detection positioning component 4, so that the input end of the light intensity detection instrument 5 is aligned with the light, effectively reducing the interference of stray light and accurately detecting the optical density of the sample reagent.

[0043] In addition, the light from the light source 11 needs to cover the wavelength range corresponding to the two key characteristic absorption peaks of phenol red reagent during the color change process, with preference given to covering 550-560nm.

[0044] Preferably, the reagent placement assembly 3 includes a first rotating support 31 and a cuvette 32;

[0045] One end of the first rotating bracket 31 is rotatably mounted to the housing assembly 2, and the other end of the first rotating bracket 31 is used to detachably mount the colorimetric cup 32, which is used to hold sample reagents.

[0046] Specifically, such as Figure 3 As shown, the rotation of the first rotating bracket 31 causes the cuvette 32 to rotate inside and outside the housing assembly 2. When the cuvette 32 is rotated inside the housing assembly 2, it is convenient to measure light intensity, while when it is rotated outside the housing assembly 2, it is convenient to place and remove the sample reagent. The cuvette 32 is detachably installed at the end of the first rotating bracket 31, which is convenient for pouring out the sample reagent after detection and for cleaning the cuvette 32.

[0047] The housing assembly 2 has an operation clearance groove on its side corresponding to the first rotating bracket 31. The rotatable end of the first rotating bracket 31 can be operated through the operation clearance groove, and the position of the cuvette 32 can be changed by directly rotating the first rotating bracket 31, which facilitates the addition and removal of sample reagents.

[0048] Preferably, the filter assembly 12 includes an adjustment member 121, a second rotating bracket 122, and a filter 123;

[0049] One end of the second rotating bracket 122 is fixedly mounted with a rotating shaft, which is rotatably mounted on the housing assembly 2. The end of the rotating shaft is provided with the adjusting member 121. The other end of the second rotating bracket 122 is provided with a filter cavity, which is used to place the filter 123.

[0050] Specifically, such as Figure 4 As shown, the filter assembly 12 includes an adjustment member 121, a second rotating bracket 122, and a filter 123. During use, the filter 123 needs to be coaxially aligned with the light source 11 so that the light from the light source 11 passes through the effective optical surface of the center of the filter 123, ensuring the intensity of the filtered light and facilitating subsequent detection of light intensity through sample reagents. Therefore, the adjustment member 121 is used to rotate the rotating shaft, thereby rotating the second rotating bracket 122 and adjusting the position of the filter 123 to ensure effective transmission of light of the target wavelength.

[0051] Preferably, the housing assembly 2 includes a supporting housing 21 and an outer cover 22;

[0052] The light-emitting component 1 and the reagent placement component 3 are respectively mounted on the support housing 21; the outer cover 22 is detachably mounted on the support housing 21 and covers the light-emitting component 1 and the reagent placement component 3.

[0053] Specifically, during use, after turning on the light emitting component 1, the outer cover 22 is installed on the support housing 21, which can further block external ambient light and reduce the impact on the detection results.

[0054] Furthermore, the support housing 21 is provided with a clearance groove 211, which is used to provide rotation space for the filter assembly 12 and the reagent placement assembly 3.

[0055] Specifically, such as Figure 5 As shown, the clearance groove 211 is adapted to the filter assembly 12 and the reagent placement assembly 3. By rotating the filter assembly 12 and the reagent placement assembly 3, the filter 123 or the cuvette 32 is rotated out from the clearance groove 211, which facilitates the replacement of sample reagents and filter 123.

[0056] Preferably, the support housing 21 is provided with a transmission component 212, which is cylindrical. One end of the transmission component 212 is located directly below the reagent placement assembly 3, and the other end of the transmission component 212 is connected to the input end of the light intensity detector. The interior of the transmission component 212 is a straight channel.

[0057] Specifically, the transmission component 212 is cylindrical with a straight internal channel, ensuring that the light emitted by the light source 11 is transmitted unobstructed to the light intensity detection instrument 5 after passing through the filter 123 and the sample reagent, effectively avoiding the influence of other light on the detection results. Both the transmission component 212 and the housing assembly 2 are made of opaque materials, effectively reducing light reflection and scattering within the housing.

[0058] Preferably, the detection positioning component 4 is provided with a vertically arranged side plate 411, the size of which is adapted to the housing assembly 2;

[0059] The outer side of the rotatable end of the first rotating bracket 31 is racetrack-shaped, and its outward straight edge is flush with the outer side of the housing assembly 2; when the housing assembly 2 is placed in the first receiving area 41, the outward straight edge of the rotatable end of the first rotating bracket 31 is connected to the inner wall of the side plate 411.

[0060] Specifically, such as Figure 2 and Figure 3 As shown, the rotatable end of the first rotating bracket 31 is racetrack-shaped, and its outward straight edge is connected to the inside of the side plate 411 of the detection positioning component 4. During the detection, after measuring the light intensity of the cuvette 32 without sample reagent, the housing assembly 2 is removed from the detection positioning component 4, the first rotating bracket 31 is rotated, sample reagent is added, and then the cuvette 32 is rotated into the housing assembly 2. Then, the housing assembly 2 is placed in the first receiving area 41 of the detection positioning component 4. At this time, the side plate 411 limits the rotation of the first rotating bracket 31 and limits the position of the cuvette 32 to directly below the filter 123, ensuring that the light can pass coaxially through the filter 123 and the sample reagent in the cuvette 32, ensuring that the light accurately passes through the center of the cuvette 32, which is consistent with the previous measurement of the blank cuvette 32, and reducing the influence of other factors on the detection results.

[0061] Preferably, the light-emitting component 1 further includes a switch 13 and a battery 14;

[0062] The battery 14 is disposed at the bottom of the housing assembly 2. The battery 14, the switch 13 and the light source 11 are electrically connected. The battery 14 is used to supply power to the light source 11, and the switch 13 is used to control the switch 13 of the light source 11.

[0063] Specifically, the battery 14 is powered by the light source 11, eliminating the need for an external power supply during use. It is readily available for testing, easy to carry, and enhances the convenience of using the device. The entire usage process is as follows: turn on the switch 13, the light source 11 emits light, cover the outer casing 22, record the measurement data from the light intensity detection instrument 5, and after completing the test, open the outer casing 22 and turn off the switch 13, thus turning off the light source 11.

[0064] Preferably, the light source 11 is an LED lamp, which has high light intensity stability and small fluctuations, improving the accuracy and repeatability of light intensity measurement. It also has low energy consumption, long lifespan, and small size, which facilitates the integration of the entire detection device and makes the entire detection device portable.

[0065] Preferably, the light intensity detection instrument 5 is a mobile phone with an ambient light sensor and internal light intensity detection software.

[0066] It is more convenient to conduct tests and has a wider range of applications. No special instruments are required; you only need to download the corresponding application software, which is compatible with the testing environment for home self-testing.

[0067] The light intensity detection software mentioned here is a well-known application software that measures light intensity based on the mobile phone's own ambient light sensor, such as a light intensity meter. It is existing technology and will not be elaborated on here.

[0068] Furthermore, the second receiving area 42 of the detection positioning component 4 is consistent with the thickness of the mobile phone, and the end of the transmission component 212 contacts the mobile phone and encloses the input end of the ambient light sensor.

[0069] Specifically, the setting of the second accommodating area 42 of the detection positioning component 4 improves the convenience of placing the mobile phone and the optical path corresponding to the input end of the ambient light sensor. Moreover, the height of the second accommodating area 42 of the detection positioning component 4 is consistent with the thickness of the mobile phone, which can ensure the stability of the housing assembly 2 during the detection process, reduce the tilt of the housing assembly 2, avoid the influence of the tilt of the housing assembly 2 on the optical path emitted by the light source 11, and ensure the accuracy of the detection results.

[0070] The technical principles of this utility model have been described above with reference to specific embodiments. These descriptions are merely for explaining the principles of this utility model and should not be construed as limiting the scope of protection of this utility model in any way. Based on this explanation, those skilled in the art can readily conceive of other specific embodiments of this utility model without any inventive effort, and these embodiments will all fall within the scope of protection of this utility model.

Claims

1. A Helicobacter pylori detection device based on optical density, characterized in that: Includes light-emitting components, housing components, reagent placement components, and detection positioning components; The light emitting component and the reagent placement component are installed inside the housing component. The light emitting component includes a light source and a filter component. The light source is installed inside the housing component, and the filter component is rotatably installed inside the housing component. The functional end of the filter component is located directly below the light source and is used to filter out light of the desired wavelength. The reagent placement assembly is rotatably mounted inside the housing assembly, and is located directly below the light emitting assembly. The reagent placement assembly is used to place sample reagents. The housing assembly is detachably mounted on the detection positioning component. The detection positioning component has a first accommodating area and a second accommodating area that are interconnected. The first accommodating area is adapted to the shape of the housing assembly and is used to accommodate the housing assembly. The second accommodating area is used to accommodate the light intensity detection instrument and is located directly below the reagent placement assembly.

2. The Helicobacter pylori detection device based on optical density according to claim 1, characterized in that: The reagent placement assembly includes a first rotating support and a cuvette; One end of the first rotating bracket is rotatably mounted to the housing assembly, and the other end of the first rotating bracket is used to detachably mount the colorimetric cup, which is used to hold sample reagents.

3. The Helicobacter pylori detection device based on optical density according to claim 1, characterized in that: The filter assembly includes an adjustment component, a second rotating support, and a filter. One end of the second rotating bracket is fixedly mounted with a rotating shaft, which is rotatably mounted on the housing assembly. The end of the rotating shaft is provided with the adjusting component, and the other end of the second rotating bracket is provided with a filter cavity for placing the filter.

4. The Helicobacter pylori detection device based on optical density according to claim 1, characterized in that: The housing assembly includes a supporting housing and an outer cover; The light-emitting component and the reagent placement component are respectively mounted on the support housing; the outer cover is detachably mounted on the support housing and covers the light-emitting component and the reagent placement component.

5. The Helicobacter pylori detection device based on optical density according to claim 4, characterized in that: The support housing is provided with a clearance groove, which is used to provide rotation space for the filter assembly and the reagent placement assembly.

6. The Helicobacter pylori detection device based on optical density according to claim 4, characterized in that: The supporting housing is equipped with a transmission component, which is cylindrical. One end of the transmission component is located directly below the reagent placement assembly, and the other end of the transmission component is connected to the input terminal of the light intensity detector. The interior of the transmission component is a straight channel.

7. The Helicobacter pylori detection device based on optical density according to claim 2, characterized in that: The detection and positioning component is provided with a vertically arranged side plate, the size of which is adapted to the housing assembly; The outer side of the rotatable end of the first rotating bracket is racetrack-shaped, and its outward straight edge is flush with the outer side of the housing assembly; when the housing assembly is placed in the first receiving area, the outward straight edge of the rotatable end of the first rotating bracket is in contact with the inner wall of the side plate.

8. The Helicobacter pylori detection device based on optical density according to claim 1, characterized in that: The light-emitting component also includes a switch and a battery; The battery is located at the bottom of the housing assembly. The battery, switch and light source are electrically connected. The battery is used to power the light source and the switch is used to control the switching of the light source.

9. The Helicobacter pylori detection device based on optical density according to claim 6, characterized in that: The light intensity detection instrument is a mobile phone equipped with an ambient light sensor and internal light intensity detection software.

10. The Helicobacter pylori detection device based on optical density according to claim 9, characterized in that: The second accommodating area of ​​the detection and positioning component is consistent with the thickness of the mobile phone, and the end of the transmission component contacts the mobile phone and encloses the input end of the ambient light sensor.

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