An experimental mouse enema device
By designing a silicone tubing and piston rod, the problems of restlessness and liquid spillage during mouse enema were solved, achieving simple operation and stable enema results.
Patent Information
- Authority / Receiving Office
- CN · China
- Patent Type
- Utility models(China)
- Current Assignee / Owner
- 赣州市人民医院
- Filing Date
- 2025-05-29
- Publication Date
- 2026-07-21
AI Technical Summary
In the enema experiment on mice, the mice tended to move around a lot, and the enema fluid was prone to overflow or splashing, which affected the rinsing effect.
A silicone tube was inserted into the mouse's anus, a silicone plug was used to hold the anus in place, and enema fluid was pushed in through a piston rod. A pressure balloon and guidewire were used to control the enema process.
It reduces mouse movement, prevents enema fluid leakage, is simple and effective to operate, and ensures the enema effect.
Smart Images
Figure CN224523710U_ABST
Abstract
Description
Technical Field
[0001] This utility model relates to the field of mouse enema test equipment technology, and in particular to an experimental mouse enema device. Background Technology
[0002] An enema is a procedure in which a certain amount of solution is administered through a rectal tube from the anus into the colon via the rectum. This helps patients defecate and expel gas, and can also be used to confirm diagnoses and administer treatments.
[0003] Enemas are a common method in pediatric care. They are used to expel feces and other substances from the rectum of children through enema fluid, making it easier to perform medical enemas such as those performed by proctoscopy. In experiments, mice are usually used first. During the enema process, mice are very prone to moving around, so a simple and convenient enema device is needed to prevent the enema fluid from overflowing or splashing out, which would affect the effectiveness of the intestinal cleansing. Summary of the Invention
[0004] To overcome the above shortcomings, the purpose of this utility model is to provide an enema device for experimental mice, which involves inserting a silicone tube into the anus of an experimental mouse, moving a silicone plug on the silicone tube to press against the mouse's buttocks, and then using a piston rod to push the enema fluid in the medicine tank into the silicone tube, which then enters the anus of the experimental mouse through the outlet hole at the front end of the silicone tube.
[0005] The technical solution of this utility model to solve its technical problem is:
[0006] An experimental mouse enema device includes a silicone tubing, a silicone stopper, and a drug loading mechanism. The silicone stopper is fitted onto the silicone tubing, and the front end of the silicone tubing has several liquid outlet holes. The drug loading mechanism includes a drug container and a piston rod movably connected to the drug container. The end of the silicone tubing is fitted onto the drug container, and the end of the piston rod has a handle.
[0007] As an improvement of this utility model, it also includes a pressure balloon, which can be fitted onto the end of the silicone tubing.
[0008] As a further improvement of this utility model, it also includes a guide wire that can extend into the silicone tubing.
[0009] As a further improvement of this utility model, the front end of the silicone tube is configured as a round head.
[0010] As a further improvement of this utility model, the front end of the silicone tube is provided with 8 to 12 liquid outlet holes.
[0011] In this invention, a silicone tube is inserted into the anus of a laboratory mouse. A silicone plug is moved along the silicone tube to press against the mouse's buttocks. Then, a piston rod pushes the enema solution from the medicine container into the silicone tube, which then enters the mouse's anus through the outlet at the front end of the silicone tube. In this invention, using a silicone tube inserted into the mouse's anus is less likely to cause a strong reaction from the mouse, making it less prone to movement. Moreover, the piston rod pushes the enema solution from the medicine container into the silicone tube and then into the mouse's anus, making the operation convenient and practical. Attached Figure Description
[0012] For ease of explanation, the present invention will be described in detail below with reference to the preferred embodiments and accompanying drawings.
[0013] Figure 1 This is a schematic diagram of the structure of this utility model;
[0014] Figure 2 This is a schematic diagram of the internal guide wire of this utility model;
[0015] Figure 3 This is a schematic diagram of the present invention with the pressure balloon attached;
[0016] Figure 4 This is a schematic diagram illustrating the application of this invention by inserting it into the anus of a laboratory mouse.
[0017] Reference numerals: 1-Silicone tubing, 11-Dispensing hole, 2-Silicone soft plug, 3-Drug loading mechanism, 31-Drug container, 32-Piston rod, 33-Handle, 4-Pressure balloon, 5-Guide wire. Detailed Implementation
[0018] To make the objectives, technical solutions, and advantages of this utility model clearer, the present utility model will be further described in detail below with reference to the accompanying drawings and embodiments. It should be understood that the specific embodiments described herein are merely illustrative of the present utility model and are not intended to limit the present utility model.
[0019] like Figures 1 to 4 As shown, this utility model discloses an experimental mouse enema device, comprising a silicone tubing 1, a silicone soft plug 2, and a drug loading mechanism 3. The front end of the silicone tubing 1 is provided with several liquid outlet holes 11, which are used to introduce enema fluid from the drug container 31 into the anus of the experimental mouse. The front end of the silicone tubing 1 is provided with 8 to 12 liquid outlet holes 11, preferably 12. In order not to damage the intestine of the experimental mouse, the front end of the silicone tubing 1 is designed to be round-headed.
[0020] In this invention, the silicone soft plug 2 is fitted onto the silicone tubing 1. The silicone soft plug 2 can slide on the silicone tubing 1. Depending on the size of the experimental mouse, the silicone soft plug 2 can be slid to hold the experimental mouse's buttocks, making it convenient to inject enema fluid.
[0021] In this invention, the drug loading mechanism 3 includes a drug container 31 and a piston rod 32 movably connected to the drug container 31. The end of the silicone tubing 1 is sleeved with the drug container 31, and the end of the piston rod 32 is provided with a handle 33. Specifically, the piston rod 32 can perform piston-like stretching movements inside the drug container 31. The drug container 31 containing enema fluid is sleeved with the end of the silicone tubing 1. After the front end of the silicone tubing 1 is inserted into the anus of the experimental mouse, the silicone soft plug 2 is slid on the silicone tubing 1 to press against the buttocks of the experimental mouse. The handle 33 is pressed to make the piston rod 32 press forward inside the drug container 31, so that the enema fluid in the drug container 31 is injected into the silicone tubing 1. The enema fluid is then introduced into the anus of the experimental mouse through the outlet 11 of the silicone tubing 1.
[0022] In this invention, a silicone tube 1 is inserted into the anus of the experimental mouse, which is less likely to cause too much reaction in the experimental mouse and makes it less likely to move around. Moreover, the enema fluid in the medicine tank 31 is pushed into the silicone tube 1 through the piston rod 32 and then into the anus of the experimental mouse. The operation is convenient and practical.
[0023] In this invention, after the enema solution is injected into the experimental mice, the drug loading mechanism 3 can be removed, and a pressure balloon 4 can be attached to the end of the silicone tubing 1. The pressure balloon 4 is observed to determine the intestinal pressure of the experimental mice. If the pressure balloon 4 is inflated, it indicates that the pressure is too high. The pressure balloon 4 should be removed, and the drug loading mechanism 3 without enema solution should be attached. The pressure can be released by pulling the handle 33, thereby avoiding discomfort caused by excessive intestinal pressure in the mice. If the pressure balloon 4 is normal, the pressure balloon 4 is kept attached to the silicone tubing 1, and the experimental mice fixed in the fixation device are observed.
[0024] In this invention, in order to better insert the silicone tubing 1 into the anus of the experimental mouse, the guide wire 5 can be inserted into the silicone tubing 1, and then the silicone tubing 1 can be inserted into the anus of the experimental mouse. The guide wire 1 plays a shaping role. After that, the guide wire is pulled out of the silicone tubing 1 and then the drug loading mechanism 3 is attached.
[0025] In this invention, the guide wire 5 is first inserted into the silicone tube 1, and then the silicone tube 1 is inserted into the anus of the experimental mouse. The silicone soft plug 2 is slid on the silicone tube 1 so that the silicone soft plug 2 presses against the experimental mouse's buttocks. Then, the drug loading mechanism 3 containing enema fluid is attached to the end of the silicone tube 1. The handle 33 of the piston rod 32 is pressed so that the piston rod 32 is pressed forward in the drug container 31, and the enema fluid is injected into the silicone tube 1 and then injected into the intestine of the experimental mouse through the outlet hole 11. After observing for a period of time, the drug loading mechanism 3 is removed, and the pressure balloon 5 is attached to the end of the silicone tube 1. The condition of the pressure balloon 5 is observed. If the pressure balloon 4 is inflated, the pressure balloon 4 is removed, and the drug loading mechanism 3 without enema fluid is attached. The pressure is released by pulling the handle 33, thereby avoiding excessive pressure in the mouse's intestinal cavity and causing discomfort. If the pressure balloon 4 is normal, the pressure balloon 4 is kept attached to the silicone tube 1, and the condition of the experimental mouse fixed in the fixation device is observed.
[0026] The above description is only a preferred embodiment of the present utility model and is not intended to limit the present utility model. Any modifications, equivalent substitutions and improvements made within the spirit and principles of the present utility model should be included within the protection scope of the present utility model.
Claims
1. An experimental mouse enema device, characterized in that, The device includes a silicone tubing, a silicone stopper, a drug loading mechanism, a pressure balloon, and a guide wire. The silicone stopper is fitted onto the silicone tubing, and the front end of the silicone tubing has several liquid outlet holes. The pressure balloon can be fitted onto the end of the silicone tubing, and the guide wire can extend into the silicone tubing. The drug loading mechanism includes a drug container and a piston rod movably connected to the drug container. The end of the silicone tubing is fitted onto the drug container, and the end of the piston rod is provided with a handle.
2. The experimental mouse enema device according to claim 1, characterized in that, The front end of the silicone tubing is rounded.
3. The experimental mouse enema device according to claim 1, characterized in that, The front end of the silicone hose is provided with 8 to 12 liquid outlet holes.