An adjustable internal fixation device for positioning of light tissue samples in centrifuge tubes

Abstract

The utility model discloses a kind of adjustable internal fixation device for positioning light tissue sample in centrifugal tube, including tube body and the tube cover of the top threaded connection of tube body, the bottom fixed connection of tube cover has the connecting pipe of intruding tube body inside, the inside threaded connection of connecting pipe has connecting column, the bottom end fixed connection of connecting column has the baffle for being used to contact with tissue sample, equidistantly set up hole structure of convenient fixed liquid outflow on baffle;By rotating connecting column, baffle can be driven to move along the axial movement of tube body, to adjust its depth of intruding tube body.The utility model drives the movement of baffle by thread rotation, realizes the depth and precision adjustable positioning of light tissue sample in centrifugal tube, effectively prevent sample floating.By locking nut locking depth, in combination with the design of scale line and transparent tube body, so that operation process is visible and quantized.Through these technical schemes, the efficiency of centrifugal separation experiment can be significantly improved, and the accuracy of detection is improved.

Description

Technical Field

[0001] This utility model relates to the field of centrifuge technology, and in particular to an adjustable internal fixation device for positioning lightweight tissue samples in centrifuge tubes. Background Technology

[0002] In histological experiments, centrifuge tubes are the basic containers used to hold tissue samples and fixatives, and to perform centrifugation or static infiltration.

[0003] However, current conventional centrifuge tubes are simply hollow structures. When processing tissue samples with a density lower than that of the fixative (such as fat and lung tissue), the samples will continue to float on the surface and cannot sink on their own. This results in the portion of the sample exposed to air not being able to fully contact the fixative, causing uneven fixation and incomplete penetration, which seriously affects the quality of tissue preservation and the accuracy of subsequent pathological analysis.

[0004] To address the above issues, we have developed an adjustable internal fixation device for positioning lightweight tissue samples in centrifuge tubes. Utility Model Content

[0005] This utility model discloses an adjustable internal fixation device for positioning lightweight tissue samples in centrifuge tubes, aiming to solve the technical problems in the background art.

[0006] To achieve the above objectives, the present invention adopts the following technical solution: An adjustable internal fixation device for positioning lightweight tissue samples in centrifuge tubes includes a tube body and a tube cap threaded to the top of the tube body. A connecting tube extending into the tube body is fixedly connected to the bottom of the tube cap. A connecting post is threaded to the inside of the connecting tube. A baffle for contacting the tissue sample is fixedly connected to the bottom end of the connecting post. The baffle has holes equidistantly opened to facilitate the outflow of fixative. By rotating the connecting column, the baffle can be driven to move axially along the tube body to adjust its depth of insertion into the tube body.

[0007] In a preferred embodiment, a reinforcing ring is fixedly sleeved on the outer side of the connecting pipe, the outer diameter of which is adapted to the inner diameter of the pipe body, for centering and stabilizing the connecting pipe within the pipe body.

[0008] In a preferred embodiment, a sealing ring is embedded on the outer side of the reinforcing ring to achieve a seal between the reinforcing ring and the inner wall of the tube.

[0009] In a preferred embodiment, a locking nut is threaded onto the outer side of the connecting post, the locking nut being used to lock and fix the relative position of the connecting post and the connecting pipe after depth adjustment.

[0010] In a preferred embodiment, the outer wall of the tube is provided with scale lines distributed along its axial direction.

[0011] In a preferred embodiment, the baffle is made of thermoplastic elastomer.

[0012] In a preferred embodiment, the tube is made of a transparent material.

[0013] The adjustable internal fixation device for positioning lightweight tissue samples in centrifuge tubes provided by this utility model has the following advantages: This invention achieves adjustable depth and precision positioning of lightweight tissue samples in centrifuge tubes by driving the movement of a baffle through threaded rotation, effectively preventing sample floating. The depth is locked by a locking nut, and the design, combined with graduation lines and a transparent tube, makes the operation process visible and quantifiable. These technical solutions significantly improve the efficiency of centrifugation experiments and enhance the accuracy of detection. Attached Figure Description

[0014] Figure 1 This is a schematic diagram of the overall structure of an adjustable internal fixation device for positioning lightweight tissue samples in centrifuge tubes, as proposed in this utility model.

[0015] Figure 2 This is an exploded top view of an adjustable internal fixation device for positioning lightweight tissue samples in centrifuge tubes, as proposed in this utility model.

[0016] Figure 3 This is an exploded view from below of an adjustable internal fixation device for positioning lightweight tissue samples in centrifuge tubes, as proposed in this utility model.

[0017] In the attached diagram: 1. Pipe body; 11. Scale line; 2. Pipe cap; 21. Connecting pipe; 22. Reinforcing ring; 23. Connecting post; 24. Locking nut; 25. Baffle plate. Detailed Implementation

[0018] The technical solutions of the embodiments of this application will be clearly and completely described below with reference to the accompanying drawings. Obviously, the described embodiments are only some embodiments of this application, and not all embodiments. The components of the embodiments of this application described and marked in the accompanying drawings can be arranged and designed in various different configurations. Therefore, the following detailed description of the embodiments of this application provided in the accompanying drawings is not intended to limit the scope of the claimed application, but merely represents selected embodiments of this application. All other embodiments obtained by those skilled in the art based on the embodiments of this application without inventive effort are within the scope of protection of this application.

[0019] This utility model discloses an adjustable internal fixation device for positioning lightweight tissue samples in centrifuge tubes.

[0020] Reference Figure 1 , Figure 2 and Figure 3 As shown, an adjustable internal fixation device for positioning lightweight tissue samples in centrifuge tubes includes a tube body 1 and a tube cap 2 threadedly connected to the top of the tube body 1. A connecting tube 21 extending into the tube body 1 is fixedly connected to the bottom of the tube cap 2. A connecting post 23 is threadedly connected to the inside of the connecting tube 21. A baffle 25 for contacting the tissue sample is fixedly connected to the bottom end of the connecting post 23. The baffle 25 has holes equidistantly opened on it to facilitate the outflow of fixative. By rotating the connecting column 23, the baffle 25 can be driven to move along the axial direction of the tube 1 to adjust its depth of insertion into the tube 1. In this embodiment: When in use, the light tissue sample is placed directly in the fixative, and then the baffle 26 is inserted into the tube 1 to limit the light tissue sample and immerse it in the fixative. Subsequently, the user can rotate the connecting column 23. Since the connecting column 23 and the connecting tube 21 are threaded together, the rotational motion is converted into linear motion of the connecting column 23 and the baffle 25, thereby adjusting the depth of the baffle 25 and the sample within the tube body 1. This structure allows the user to precisely position the sample at any height within the tube body 1 according to experimental needs (such as density gradient centrifugation in centrifuge solutions of different concentrations). After centrifugation, the sample remains stably in the predetermined position. Finally, tighten the tube cap 2 to place the entire suspension system within the tube body 1.

[0021] Reference Figure 1 , Figure 2 and Figure 3 As shown, in a preferred embodiment, a reinforcing ring 22 is fixedly sleeved on the outer side of the connecting pipe 21. The outer diameter of the reinforcing ring 22 is adapted to the inner diameter of the pipe body 1, for centering and stabilizing the connecting pipe 21 within the pipe body 1. In this embodiment, when the cap 2 is screwed into the tube body 1, the outer wall of the reinforcing ring 22 will contact and slide with the inner wall of the tube body 1, which can effectively prevent the slender connecting tube 21 from tilting or shaking due to uneven force. This ensures that the connecting tube 21, the connecting column 23 and the baffle 25 are always on the axis of the tube body 1. This not only ensures the structural stability of the device and avoids the collision between the baffle 25 and the tube wall, but also ensures that the tissue sample is subjected to uniform force and accurate positioning during centrifugation, thus improving the repeatability and reliability of the experiment.

[0022] Reference Figure 1 , Figure 2 and Figure 3As shown, in a preferred embodiment, a sealing ring is embedded on the outer side of the reinforcing ring 22 to achieve a seal between the reinforcing ring 22 and the inner wall of the tube body 1; In this embodiment, the sealing ring embedded on the outside of the reinforcing ring 22 forms an interference fit with the inner wall of the tube body 1 after the tube cap 2 is tightened, resulting in elastic deformation. This fills the gap between the reinforcing ring 22 and the inner wall of the tube body 1, making it convenient for the user to insert the reinforcing ring 22 into the tube body 1. At the same time, after deformation, the resilience of the sealing ring is reduced, which is sufficient to ensure that the reinforcing ring 22 will not shake excessively during centrifugation.

[0023] Reference Figure 1 , Figure 2 and Figure 3 As shown, in a preferred embodiment, a locking nut 24 is threaded onto the outer side of the connecting post 23. The locking nut 24 is used to lock and fix the relative position of the connecting post 23 and the connecting tube 21 after depth adjustment. In this embodiment: After adjusting the baffle 25 to the target depth by rotating the connecting column 23, tighten the locking nut 24 so that it fits tightly against the end face of the connecting tube 21. The locking nut 24 generates friction to lock the threaded pair between the connecting column 23 and the connecting tube 21, eliminating any possible small gaps between them. This effectively prevents the connecting column 23 from rotating or shifting unexpectedly due to vibration and inertial forces during subsequent operations or high-speed centrifugation, thereby ensuring the stability of the sample depth parameter and improving the reliability and accuracy of the device.

[0024] Reference Figure 1 , Figure 2 and Figure 3 As shown, in a preferred embodiment, the outer wall of the tube body 1 is provided with scale lines 11 distributed along its axial direction; In this embodiment, when adjusting the depth of the baffle 25, the user can use the end of the baffle 25 or the sample itself as an indicator point and compare it with the scale line 11 on the tube wall for accurate reading and high-precision positioning.

[0025] Reference Figure 1 , Figure 2 and Figure 3 As shown, in a preferred embodiment, the baffle 25 is made of thermoplastic elastomer; In this embodiment, a baffle 25 made of TPE is used. Its soft texture reduces mechanical damage to fragile samples and maintains sample integrity. Furthermore, TPE has good biocompatibility and chemical stability, and is unlikely to react with experimental reagents.

[0026] Reference Figure 1 , Figure 2 and Figure 3As shown, in a preferred embodiment, the tube body 1 is made of a transparent material; In this embodiment, the tube 1 is made of transparent material, such as glass or transparent plastic, so that the operator can directly and clearly observe the inside of the tube 1.

[0027] The above description is merely a preferred embodiment of this utility model, but the protection scope of this utility model is not limited thereto. The substitutions may be replacements of some structures, devices, or method steps, or they may be complete technical solutions. Equivalent substitutions or modifications made based on the technical solution and inventive concept of this utility model should all be covered within the protection scope of this utility model.

Claims

1. An adjustable internal fixation device for positioning lightweight tissue samples in centrifuge tubes, comprising a tube body (1) and a cap (2) threadedly connected to the top of the tube body (1), characterized in that: The bottom of the tube cap (2) is fixedly connected to a connecting tube (21) that extends into the tube body (1). The connecting tube (21) is threaded with a connecting post (23). The bottom end of the connecting post (23) is fixedly connected to a baffle (25) for contacting the tissue sample. The baffle (25) has holes equidistantly opened to facilitate the flow of fixative. By rotating the connecting column (23), the baffle (25) can be driven to move along the axial direction of the tube (1) to adjust its depth of insertion into the tube (1).

2. The adjustable internal fixation device for positioning lightweight tissue samples in centrifuge tubes according to claim 1, characterized in that, A reinforcing ring (22) is fixedly sleeved on the outside of the connecting pipe (21). The outer diameter of the reinforcing ring (22) is adapted to the inner diameter of the pipe body (1) for centering and stabilizing the connecting pipe (21) inside the pipe body (1).

3. The adjustable internal fixation device for positioning lightweight tissue samples in centrifuge tubes according to claim 2, characterized in that, A sealing ring is embedded on the outer side of the reinforcing ring (22) to achieve a seal between the reinforcing ring (22) and the inner wall of the tube body (1).

4. The adjustable internal fixation device for positioning lightweight tissue samples in centrifuge tubes according to claim 1, characterized in that, The outer side of the connecting post (23) is threaded with a locking nut (24), which is used to lock and fix the relative position of the connecting post (23) and the connecting tube (21) after depth adjustment.

5. The adjustable internal fixation device for positioning lightweight tissue samples in centrifuge tubes according to claim 1, characterized in that, The outer wall of the tube (1) is provided with scale lines (11) distributed along its axial direction.

6. The adjustable internal fixation device for positioning lightweight tissue samples in centrifuge tubes according to claim 1, characterized in that, The baffle (25) is made of thermoplastic elastomer.

7. The adjustable internal fixation device for positioning lightweight tissue samples in centrifuge tubes according to claim 1, characterized in that, The tube (1) is made of a transparent material.

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