A saccharide disease quantitative detection kit with anti-interference function

Abstract

The utility model provides a kind of with anti-interference function saccharide disease quantitative detection kit belongs to saccharide disease kit technical field, to solve the problem of poor anti-interference ability;Including box body;The box body top movably provided with cover plate, and cover plate both sides are fixedly provided with auxiliary structure;The detection structure is placed in the placing groove A, and sample processing assembly is placed in the placing groove B;The sample processing assembly includes: processing cylinder;Processing cylinder is placed in the placing groove B, and processing cylinder is internally provided with hemoglobin adsorbent, lipid scavenger and ph stabilizer;Through the hemoglobin adsorbent, lipid scavenger and ph stabilizer internally provided with processing cylinder;Sample can be treated before detection;Further filtration can be carried out to sample by filter membrane, remove the impurities such as small particles, cell fragments possibly existing in sample, further purify sample, reduce the interference of impurities to detection.

Description

Technical Field

[0001] This invention belongs to the technical field of reagent kits for carbohydrate diseases, and more specifically, relates to a quantitative detection reagent kit for carbohydrate diseases with anti-interference function. Background Technology

[0002] In the diagnosis, disease monitoring, and treatment efficacy evaluation of carbohydrate-related diseases (such as diabetes mellitus, which are characterized by abnormal carbohydrate metabolism), accurate quantitative detection of carbohydrate-related indicators is a crucial step. Accurate detection of carbohydrate concentration in blood or other body fluids can provide doctors with key information for developing reasonable treatment plans, adjusting drug dosages, and assessing patient prognosis.

[0003] Currently, common methods and kits for quantitative carbohydrate detection on the market have poor anti-interference capabilities. During clinical sample collection and testing, samples are often mixed with various interfering substances. For example, in blood samples, hemolysis can lead to the release of hemoglobin, and abnormal lipid metabolism can cause hyperlipidemia. At the same time, the pH of the sample may also deviate from the normal range due to individual differences or disease states. These interfering substances can significantly affect the test results, causing a large deviation between the measured value and the true value, which in turn affects the doctor's accurate judgment of the condition. Utility Model Content

[0004] To address the aforementioned technical problems, this invention provides a quantitative detection kit for diabetes mellitus with anti-interference capabilities, thereby resolving the issue of poor anti-interference ability mentioned in the background section.

[0005] This utility model discloses a quantitative detection kit for diabetes mellitus with anti-interference function, achieved through the following specific technical means: A quantitative detection kit for carbohydrate diseases with anti-interference function includes a box body; a placement pad is fixedly disposed inside the box body, and a placement slot A and an auxiliary slot are opened inside the placement pad, with the auxiliary slots located on both sides of the placement slot A; a placement slot B is also opened inside the placement pad; a cover plate is movably disposed on the top of the box body, and auxiliary structures are fixedly disposed on both sides of the cover plate; a detection structure is placed inside the placement slot A, and a sample processing component is placed inside the placement slot B. The sample processing assembly includes: a processing tube, a fixing ring, a tube cap, a conical head, and a filter membrane; the processing tube is placed inside the placement slot B, and the processing tube contains a hemoglobin adsorbent, a lipid scavenger, and a pH stabilizer; the fixing ring is fixedly disposed on the outside of the processing tube; the tube cap is disposed on the outside of the processing tube by a threaded connection, and the outside of the tube cap fits against the outside of the fixing ring; the conical head is fixedly disposed at the end of the processing tube; and the filter membrane is fixedly disposed inside the processing tube.

[0006] Furthermore, a sealing ring is fixedly provided on the top of the box body, and a sealing groove is provided at the bottom of the cover plate, with a sealing ring movably provided inside the sealing groove; a pressure pad A is fixedly provided at the bottom of the cover plate, and a pressure pad B is also fixedly provided at the bottom of the cover plate, with the bottom of the pressure pad B fitting against the outside of the processing cylinder.

[0007] Furthermore, the box body is fixedly provided with two sets of fixing seats on both sides, and the fixing seats are arranged symmetrically; the fixing seats are U-shaped, and the fixing seats have connecting holes on both sides.

[0008] Furthermore, the auxiliary structure includes: an auxiliary seat, an auxiliary block, a limiting groove, and a limiting plate; the auxiliary seat is fixedly disposed on both sides of the cover plate and movably disposed inside the fixed seat; the auxiliary block is slidably disposed inside both sides of the auxiliary seat, and the bottom of one end of the auxiliary block is configured as a beveled structure; a spring is disposed between the other end of the auxiliary block and the interior of the auxiliary seat, and the auxiliary block is slidably disposed inside the connecting hole; the limiting groove is opened on the top of the auxiliary seat; the limiting plate is slidably disposed inside the limiting groove, and the limiting plate is fixedly connected to the auxiliary block.

[0009] Furthermore, the detection structure includes: a detection plate and detection holes; the detection plate is placed inside the placement groove A, and the top of the detection plate is in contact with the bottom of the pressure pad A; the detection holes are opened inside the top side of the detection plate, and the detection holes are arranged in a rectangular array, and the bottom of the detection holes is coated with anti-glucose oxidase antibody.

[0010] Furthermore, the sample processing assembly also includes: a fixing frame, an adjusting screw, and a baffle; the fixing frame is fixedly disposed on one side of the processing cylinder; the adjusting screw is threadedly connected to the inside of the fixing frame, and a knob is fixedly disposed at the top of the adjusting screw; the baffle is slidably disposed inside the processing cylinder and the fixing frame, and the baffle is rotatably connected to the adjusting screw.

[0011] Compared with the prior art, the present invention has the following beneficial effects: 1. In this invention, the hemoglobin adsorbent, lipid scavenger, and pH stabilizer installed inside the processing tube enable the following: The hemoglobin adsorbent specifically adsorbs hemoglobin from the sample before testing, preventing non-specific binding with the detection reagent and thus avoiding interference with the detection signal; the lipid scavenger effectively removes lipid components from the sample, preventing lipid particles from clogging the detection channel or affecting the contact between the reagent and the target sugars, ensuring detection sensitivity; the pH stabilizer maintains the sample's pH within a suitable range, ensuring that enzyme-catalyzed reactions and other detection processes occur in a stable acidic or alkaline environment, reducing the impact of pH fluctuations on the detection results, thereby significantly improving the accuracy and reliability of the detection.

[0012] 2. In this utility model, the filter membrane can further filter the sample, remove impurities such as tiny particles and cell debris that may exist in the sample, further purify the sample, reduce the interference of impurities on the detection, and make the detection results more accurately reflect the actual sugar content in the sample.

[0013] 3. In this utility model, by setting an adjusting screw, a baffle, and a fixing frame, the position of the baffle inside the processing cylinder can be controlled by the adjusting screw, thereby accurately controlling the outflow of the sample. The operation is simple and intuitive, requiring no complicated operating steps or professional skills, thus improving the efficiency and accuracy of sample processing. Attached Figure Description

[0014] Figure 1 This is a schematic diagram of the overall structure of this utility model.

[0015] Figure 2 This is a schematic diagram of the internal structure of the box body of this utility model.

[0016] Figure 3 This is a schematic diagram of the upper surface structure of the placement pad of this utility model.

[0017] Figure 4 This is a schematic diagram of the internal structure of the processing cylinder of this utility model.

[0018] Figure 5 This is a schematic diagram of the lower surface structure of the cover plate of this utility model.

[0019] Figure 6 This is a schematic diagram of the auxiliary structure of this utility model.

[0020] In the diagram, the correspondence between component names and drawing numbers is as follows: 1. Box body; 101. Cover plate; 102. Sealing ring; 103. Sealing groove; 104. Pressure pad A; 105. Fixing base; 106. Connecting hole; 107. Placement pad; 108. Placement groove A; 109. Auxiliary groove; 1010. Placement groove B; 1011. Pressure pad B; 2. Auxiliary structure; 201. Auxiliary seat; 202. Auxiliary block; 203. Limiting groove; 204. Limiting plate; 3. Detection structure; 301. Detection plate; 302. Detection hole; 4. Sample processing components; 401. Processing cylinder; 402. Fixing ring; 403. Cylinder cap; 404. Conical head; 405. Filter membrane; 406. Fixing frame; 407. Adjusting screw; 408. Baffle. Detailed Implementation

[0021] The embodiments of this utility model will be described in further detail below with reference to the accompanying drawings and examples.

[0022] Example 1: As shown in the attached document Figure 1 To be continued Figure 6 As shown: This utility model provides a quantitative detection kit for carbohydrate diseases with anti-interference function, including a box body 1; a placement pad 107 is fixedly disposed inside the box body 1, and a placement slot A108 and an auxiliary slot 109 are opened inside the placement pad 107, with the auxiliary slot 109 located on both sides of the placement slot A108; a placement slot B1010 is also opened inside the placement pad 107; a cover plate 101 is movably disposed on the top of the box body 1, and auxiliary structures 2 are fixedly disposed on both sides of the cover plate 101; a detection structure 3 is placed inside the placement slot A108, and a sample processing component 4 is placed inside the placement slot B1010; In this embodiment, the sample processing component 4 includes: a processing cylinder 401, a fixing ring 402, a cylinder cover 403, a conical head 404, and a filter membrane 405; the processing cylinder 401 is placed inside the placement groove B1010, and the processing cylinder 401 is provided with a hemoglobin adsorbent, a lipid scavenger, and a pH stabilizer; the fixing ring 402 is fixedly disposed on the outside of the processing cylinder 401; the cylinder cover 403 is disposed on the outside of the processing cylinder 401 by a threaded connection, and the outside of the cylinder cover 403 fits against the outside of the fixing ring 402; the conical head 404 is fixedly disposed at the end of the processing cylinder 401; the filter membrane... 405 is fixedly installed inside the processing cylinder 401; a sealing ring 102 is fixedly installed on the top of the box body 1, and a sealing groove 103 is opened at the bottom of the cover plate 101, and the sealing ring 102 is movably installed inside the sealing groove 103; a pressure pad A104 is fixedly installed at the bottom of the cover plate 101, and a pressure pad B1011 is also fixedly installed at the bottom of the cover plate 101, and the bottom of the pressure pad B1011 is in contact with the outside of the processing cylinder 401; a fixing seat 105 is fixedly installed on both sides of the box body 1, and two sets of fixing seats 105 are symmetrically arranged; the fixing seat 105 is U-shaped, and The fixing base 105 has connection holes 106 on both sides; the detection structure 3 includes a detection plate 301 and detection holes 302; the detection plate 301 is placed inside the placement groove A108, and the top of the detection plate 301 is in contact with the bottom of the pressure pad A104; the detection holes 302 are opened inside the top side of the detection plate 301, and the detection holes 302 are arranged in a rectangular array, and the bottom of the detection holes 302 is coated with anti-glucose oxidase antibody; its specific function is: through the hemoglobin adsorbent, lipid scavenger and pH stabilizer set inside the processing cylinder 401; it can detect During sample pretreatment, the hemoglobin adsorbent specifically adsorbs hemoglobin in the sample, preventing non-specific binding with the detection reagents and thus avoiding interference with the detection signal. The lipid scavenger effectively removes lipid components from the sample, preventing lipid particles from clogging the detection channel or affecting the contact between the reagent and the target sugars, ensuring the sensitivity of the detection. The pH stabilizer maintains the sample's pH within a suitable range, ensuring that detection processes such as enzymatic reactions are carried out in a stable acidic or alkaline environment, reducing the impact of pH fluctuations on the detection results, thereby significantly improving the accuracy and reliability of the detection.

[0023] Example 2: As shown in the attached document Figure 5 With appendix Figure 6As shown: Based on Embodiment 1, the auxiliary structure 2 includes: an auxiliary seat 201, an auxiliary block 202, a limiting groove 203, and a limiting plate 204; the auxiliary seat 201 is fixedly disposed on both sides of the cover plate 101, and the auxiliary seat 201 is movably disposed inside the fixed seat 105; the auxiliary block 202 is slidably disposed inside both sides of the auxiliary seat 201, and the bottom of one end of the auxiliary block 202 is set as a beveled structure; a spring is provided between the other end of the auxiliary block 202 and the interior of the auxiliary seat 201, and the auxiliary block 202 is slidably disposed inside the connecting hole 106; the limiting groove 203 is opened at the top of the auxiliary seat 201; the limiting plate 204 is slidably disposed inside the limiting groove 203, and the limiting plate 204 is fixedly connected to the auxiliary block 202; its specific function is: the beveled structure of the auxiliary block 202 facilitates insertion into the connecting hole 106, realizing a reliable connection between the cover plate 101 and the box body 1.

[0024] Example 3: As shown in the attached document Figure 4 As shown: Based on Embodiment 1 and Embodiment 2, the sample processing component 4 further includes: a fixing frame 406, an adjusting screw 407, and a baffle 408; the fixing frame 406 is fixedly disposed on one side of the processing cylinder 401; the adjusting screw 407 is threadedly connected to the inside of the fixing frame 406, and a knob is fixedly disposed at the top of the adjusting screw 407; the baffle 408 is slidably disposed inside the processing cylinder 401 and the fixing frame 406, and the baffle 408 is rotatably connected to the adjusting screw 407; its specific function is: by providing the adjusting screw 407, the baffle 408, and the fixing frame 406, the position of the baffle 408 inside the processing cylinder 401 can be controlled by the adjusting screw 407, thereby precisely controlling the outflow of the sample.

[0025] The specific usage and function of this embodiment are as follows: In this invention, the auxiliary block 202 is pulled by the limiting plate 204, causing the auxiliary block 202 to slide out of the connecting hole 106, thus separating the auxiliary seat 201 from the fixed seat 105; then the cover plate 101 is removed; then the processing tube 401 is taken out from the placement slot B1010; then the tube cover 403 is opened; the collected blood sample is slowly poured into the processing tube 401, and the sample volume should be controlled within a suitable range of the capacity of the processing tube 401; the blood sample reacts with the hemoglobin adsorbent, lipid scavenger and pH stabilizer in the processing tube 401; then the adjusting screw 407 is rotated, and the adjusting screw 407 uses the thread structure to drive the baffle 408 to move a specified distance; the blood sample flows through the filter membrane 405 to the conical head 404; the filter membrane 405 filters the blood sample... Impurities are filtered out; a blood sample is dripped into the detection well 302 using a conical head 404; the blood sample reacts fully with the anti-glucose oxidase antibody coated on the bottom of the detection well 302; after the reaction is complete, the signal in the detection well 302 can be detected and analyzed using appropriate detection equipment (such as an ELISA reader), and quantitative data of sugar-related indicators in the sample can be obtained based on the detection results; the pressure pad A104 will adhere to the top of the detection plate 301, applying appropriate pressure to the detection plate 301 to firmly fix it in the placement groove A108; the pressure pad B1011 will adhere to the outside of the processing cylinder 401, fixing and protecting the processing cylinder 401; at the same time, the sealing ring 102 and the sealing groove 103 form a tight seal to ensure the storage environment inside the box 1.

Claims

1. A quantitative detection kit for carbohydrate diseases with anti-interference function, characterized in that, include: Box body (1); a placement pad (107) is fixedly installed inside the box body (1), and a placement groove A (108) and an auxiliary groove (109) are opened inside the placement pad (107), and the auxiliary groove (109) is located on both sides of the placement groove A (108); a placement groove B (1010) is also opened inside the placement pad (107); a cover plate (101) is movably installed on the top of the box body (1), and auxiliary structures (2) are fixedly installed on both sides of the cover plate (101); a detection structure (3) is placed inside the placement groove A (108), and a sample processing component (4) is placed inside the placement groove B (1010); The sample processing component (4) includes: a processing cylinder (401), a fixing ring (402), a cylinder cover (403), a conical head (404), and a filter membrane (405); the processing cylinder (401) is placed inside the placement groove B (1010), and the processing cylinder (401) is provided with hemoglobin adsorbent, lipid scavenger, and pH stabilizer; the fixing ring (402) is fixedly disposed on the outside of the processing cylinder (401); the cylinder cover (403) is disposed on the outside of the processing cylinder (401) by a threaded connection, and the outside of the cylinder cover (403) is in contact with the outside of the fixing ring (402); the conical head (404) is fixedly disposed at the end of the processing cylinder (401); and the filter membrane (405) is fixedly disposed inside the processing cylinder (401).

2. The quantitative detection kit for carbohydrate diseases with anti-interference function according to claim 1, characterized in that: The top of the box body (1) is fixedly provided with a sealing ring (102), and the bottom of the cover plate (101) is provided with a sealing groove (103), and the sealing ring (102) is movably provided inside the sealing groove (103); the bottom of the cover plate (101) is fixedly provided with a pressure pad A (104), and the bottom of the cover plate (101) is also fixedly provided with a pressure pad B (1011), and the bottom of the pressure pad B (1011) is in contact with the outside of the processing cylinder (401).

3. The quantitative detection kit for carbohydrate diseases with anti-interference function according to claim 1, characterized in that: The box body (1) is fixedly provided with two fixed seats (105) on both sides, and the fixed seats (105) are arranged in two sets symmetrically; the fixed seats (105) are U-shaped, and the fixed seats (105) are provided with connecting holes (106) on both sides.

4. The quantitative detection kit for carbohydrate diseases with anti-interference function according to claim 3, characterized in that: The auxiliary structure (2) includes: an auxiliary seat (201), an auxiliary block (202), a limiting groove (203), and a limiting plate (204); the auxiliary seat (201) is fixedly disposed on both sides of the cover plate (101), and the auxiliary seat (201) is movably disposed inside the fixed seat (105); the auxiliary block (202) is slidably disposed inside both sides of the auxiliary seat (201), and the bottom of one end of the auxiliary block (202) is set as a beveled structure; a spring is provided between the other end of the auxiliary block (202) and the inside of the auxiliary seat (201), and the auxiliary block (202) is slidably disposed inside the connecting hole (106); the limiting groove (203) is opened on the top of the auxiliary seat (201); the limiting plate (204) is slidably disposed inside the limiting groove (203), and the limiting plate (204) is fixedly connected to the auxiliary block (202).

5. The quantitative detection kit for carbohydrate diseases with anti-interference function according to claim 2, characterized in that: The detection structure (3) includes: a detection plate (301) and a detection hole (302); the detection plate (301) is placed inside the placement groove A (108), and the top of the detection plate (301) is in contact with the bottom of the pressure pad A (104); the detection hole (302) is opened inside the top side of the detection plate (301), and the detection hole (302) is opened in a rectangular array, and the bottom of the detection hole (302) is coated with an anti-glucose oxidase antibody.

6. The quantitative detection kit for carbohydrate diseases with anti-interference function according to claim 1, characterized in that: The sample processing component (4) further includes: a fixing frame (406), an adjusting screw (407), and a baffle (408); the fixing frame (406) is fixedly disposed on one side of the processing cylinder (401); the adjusting screw (407) is disposed inside the fixing frame (406) by a threaded connection, and a knob is fixedly disposed at the top of the adjusting screw (407); the baffle (408) is slidably disposed inside the processing cylinder (401) and the fixing frame (406), and the baffle (408) is rotatably connected to the adjusting screw (407).

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