sample analyzer

Abstract

The utility model discloses a sample analyzer, include: sample dispensing mechanism is used for sample's suction dispensing, reagent dispensing mechanism is used for reagent's suction dispensing, first detection pool is used for white blood cell classification detection with sample and reagent mix, second detection pool is used for red blood cell detection with sample and reagent mix, third detection pool is used for CRP / SAA detection with sample and reagent mix, first detection pool, second detection pool and third detection pool linear distribution along horizontal direction, first drive mechanism is used for driving sample dispensing mechanism, reagent dispensing mechanism linear movement along horizontal direction, completes sample and reagent's suction and to the dispensing operation of detection pool. The utility model discloses multiple detection pool along linear distribution, not only can realize multiple project's simultaneous detection, and sample dispensing mechanism and reagent dispensing mechanism can linear movement along horizontal direction, has reduced the moving path of sample dispensing mechanism and reagent dispensing mechanism, has improved the transfer efficiency of dispensing mechanism.

Description

Technical Field

[0001] This utility model relates to the field of medical device technology, specifically to a sample analyzer. Background Technology

[0002] Sample analyzers are widely used testing instruments in the field of in vitro diagnostics. They obtain clinical diagnostic information by analyzing human blood and body fluid samples, providing a basis for disease diagnosis and assessment of bodily functions. To increase the throughput and functionality of existing sample analyzers, it is necessary to expand the capacity of the test cells and reagents, as well as allocate more installation space. This means that the more comprehensive and higher-throughput the testing equipment, the larger the space it occupies. This undoubtedly presents a significant challenge to the current demand for portability and miniaturization.

[0003] In addition, as the size of testing equipment gradually increases, the transit time of samples and reagents within the testing equipment will also be extended. With the testing duration remaining unchanged, this will lead to an increase in the time required for a single test, thereby affecting the testing efficiency of the equipment. Summary of the Invention

[0004] This utility model discloses a sample analyzer to solve the problems of large instrument size and long sample and reagent transfer time in the prior art.

[0005] To solve the above-mentioned technical problems, the present invention adopts the following technical solution: A sample analyzer, comprising: Sample dispensing mechanism, used for sample aspiration and dispensing; A reagent dispensing mechanism is used for the aspiration and dispensing of reagents. The first detection chamber is used to mix the samples and reagents for DIFF / NRBC / RET detection; The second detection chamber is used to mix the samples and reagents for RBC / PLT / HGB detection; The third detection chamber is used to mix samples and reagents for CRP / SAA detection; The first detection pool, the second detection pool, and the third detection pool are distributed in a straight line along the horizontal direction; The first driving mechanism is used to drive the sample dispensing mechanism and the reagent dispensing mechanism to move linearly in the horizontal direction, so as to complete the sample and reagent aspiration and dispensing operation into the detection cell.

[0006] Furthermore, the sample dispensing mechanism along the horizontal straight line is provided with multiple first stopping points, including a sample aspiration position, a first sample dispensing position, a second sample dispensing position, and a third sample dispensing position, for sample aspiration and stopping when dispensing samples into the first detection pool, the second detection pool, and the third detection pool.

[0007] Furthermore, the reagent dispensing mechanism along the horizontal straight line is provided with multiple second stopping points, including a first reagent aspiration position, a first reagent addition position, a second reagent addition position, a third reagent addition position, and a second reagent aspiration position, for reagent aspiration and stopping when adding reagent to the first detection pool, the second detection pool, and the third detection pool.

[0008] Furthermore, it also includes a first reagent compartment and a second reagent compartment; the first reagent compartment is located on one side of the first detection pool, and a first reagent aspiration position is correspondingly provided on the top; the second reagent compartment is located on one side of the third detection pool, and a second reagent aspiration position is correspondingly provided on the top.

[0009] Furthermore, it also includes a second sample delivery mechanism for transporting sample tubes, including a sample placement slot for placing sample tubes; a support frame, on which the sample placement slot is slidably mounted; and multiple third stopping points are provided along the moving path of the sample placement slot, including: The first injection position is used for injecting routine samples; The second injection position is used for injection of higher priority samples; The sampling position is used by the sample dispensing mechanism to draw samples from the sample tube; The second driving mechanism is used to drive the sample placement slot to move to the first injection position, the second injection position, or the aspiration position respectively, to complete the injection and aspiration operation of regular samples or high-priority samples.

[0010] Furthermore, the sample placement slot includes: The first placement slot is for placing ordinary sample tubes; The second placement slot is used for placing micro-volume blood collection tubes; The first placement slot and the second placement slot are arranged side by side on the second drive mechanism.

[0011] Furthermore, an extrusion member is rotatably mounted on the side of the first placement slot facing the second placement slot; an elastic member is provided on the support frame on the side of the extrusion member away from the first placement slot.

[0012] Furthermore, the extrusion component includes an extrusion plate rotatably mounted at the bottom of the first placement groove; an extrusion block is provided on the top of the extrusion plate, and the extrusion block can extend into the first placement groove; limiting platforms are provided on both sides of the extrusion block, which can limit the distance the extrusion block extends into the first placement groove.

[0013] Furthermore, the elastic element includes a fixing plate vertically fixed on the support frame; a fixing block is horizontally installed on the top of the fixing plate facing the first placement groove; both sides of the fixing block are provided with through holes communicating with the fixing plate; a guide rod is slidably sleeved in the through hole; a blocking part is fixed at one end of the guide rod near the first placement groove, and the other end extends to the outside of the fixing plate; a baffle is provided on the guide rod between the fixing block and the fixing plate; a spring is sleeved on the guide rod between the baffle and the fixing plate.

[0014] Furthermore, it also includes: a first shaking mechanism and a second shaking mechanism; the first shaking mechanism includes a sample tube clamping device, which is disposed above the first injection position for gripping and shaking ordinary sample tubes; the second shaking mechanism is disposed on one side of the first shaking mechanism for shaking micro-volume blood collection tubes.

[0015] This utility model adopts the above technical solution and has the following advantages: This invention features multiple detection pools arranged linearly, enabling simultaneous detection of multiple items. Furthermore, the sample dispensing mechanism and reagent dispensing mechanism can move linearly in the horizontal direction, reducing their movement paths and improving their transfer efficiency. Attached Figure Description

[0016] Figure 1 This is a schematic diagram of the sample analyzer of this utility model; Figure 2 This is a schematic diagram of the first and second stopping points of this utility model; Figure 3 This is a schematic diagram of the structure of the first sample injection mechanism of this utility model; Figure 4 This is a schematic diagram of the third stopping point of this utility model; Figure 5 This is a schematic diagram of the structure of the second injection mechanism of this utility model; Figure 6 This is a schematic diagram of the sample placement slot of this utility model; Figure 7 This is a schematic diagram of the structure of the extrusion part of this utility model; Figure 8 This is a schematic diagram of the structure of the elastic element of this utility model; Figure 9 This is a schematic diagram of the structure of the fixing block of this utility model.

[0017] Figure reference numerals: 1-Sample dispensing mechanism; 2-Reagent dispensing mechanism; 3-First detection cell; 4-Second detection cell; 5-Third detection cell; 6-First driving mechanism; 7-Sampling position; 8-First sample loading position; 9-Second sample loading position; 10-Third sample loading position; 11-First reagent suction position; 12-First reagent loading position; 13-Second reagent loading position; 14-Third reagent loading position; 15-Second reagent suction position; 16-First injection mechanism; 17-Second injection mechanism; 18-First working panel; 19-Second working panel; 20-Rotation mechanism 21-First injection position; 22-Second injection position; 23-Second drive mechanism; 24-First placement slot; 25-Second placement slot; 26-Extrusion piece; 27-Support frame; 28-Extrusion plate; 29-Extrusion block; 30-Limiting stage; 31-Arc-shaped convex surface; 32-Fixing plate; 33-Fixing block; 34-Through hole; 35-Guide rod; 36-Blocking part; 37-Baffle plate; 38-Spring; 39-Roller; 40-First shaking mechanism; 41-Second shaking mechanism; 42-First reagent compartment; 43-Second reagent compartment. Detailed Implementation

[0018] The technical solutions in the embodiments of this application are described clearly and completely below. Obviously, the described embodiments are only some embodiments of this application, and not all embodiments. Based on the embodiments of this utility model, all other embodiments obtained by those of ordinary skill in the art without creative effort are within the protection scope of this utility model.

[0019] like Figure 1 As shown, a sample analyzer includes a sample dispensing mechanism 1 for sample aspiration and dispensing; a reagent dispensing mechanism 2 for reagent aspiration and dispensing; a first detection cell 3 for mixing samples and reagents for DIFF / NRBC / RET detection; a second detection cell 4 for mixing samples and reagents for RBC / PLT / HGB detection; and a third detection cell 5 for mixing samples and reagents for CRP / SAA detection. The first detection cell 3, the second detection cell 4, and the third detection cell 5 are linearly distributed in the horizontal direction. A first driving mechanism 6 drives the sample dispensing mechanism 1 and the reagent dispensing mechanism 2 to move linearly in the horizontal direction, thereby completing the sample and reagent aspiration and dispensing operations into the detection cells.

[0020] This invention features multiple detection pools arranged linearly, enabling simultaneous detection of multiple items. Furthermore, the sample dispensing mechanism 1 and reagent dispensing mechanism 2 can move linearly in the horizontal direction, reducing their movement paths and improving their transfer efficiency.

[0021] like Figure 2As shown, the sample dispensing mechanism 1 along the horizontal straight line is provided with multiple first stopping points, including a suction position 7, a first sample addition position 8, a second sample addition position 9 and a third sample addition position 10, which are used for sample aspiration and stopping when adding samples to the first detection pool 3, the second detection pool 4 and the third detection pool 5.

[0022] The reagent dispensing mechanism 2 along the horizontal straight line is provided with multiple second stopping points, including a first reagent aspiration position 11, a first reagent addition position 12, a second reagent addition position 13, a third reagent addition position 14 and a second reagent aspiration position 15, which are used for reagent aspiration and stopping when adding reagents to the first detection pool 3, the second detection pool 4 and the third detection pool 5.

[0023] The first detection pool 3 is connected to the first detection component (not shown) and contains three first mixing tanks for DIFF / NRBC / RET detection, respectively; the second detection pool 4 is connected to the second detection component (not shown) and contains one second mixing tank for RBC / PLT / HGB detection; the third detection pool 5 is connected to the third detection component (not shown) and contains two third mixing tanks for CRP / SAA detection, respectively; each first mixing tank only supports the detection of its corresponding item and does not support mixing; each third mixing tank supports both CRP and SAA detection, that is, it supports mixing between items.

[0024] Furthermore, it also includes a first injection mechanism 16 for transporting the sample rack and a second injection mechanism 17 for transporting the sample tube.

[0025] like Figure 3 As shown, the first sample introduction mechanism 16 includes a first working panel 18, a second working panel 19, and a transfer mechanism 20. Each working panel has a pushing mechanism at its bottom for pushing the sample rack. After the operator places the sample rack on the first working panel 18, the pushing mechanism pushes the sample rack to the transfer mechanism 20. The transfer mechanism 20 carries the sample rack towards the aspiration position 7. The sample tubes on the sample rack are picked up and transferred to the second sample introduction mechanism 17. The second sample introduction mechanism 17 carries the sample tubes to the aspiration position 7, where the sample dispensing mechanism 1 aspirates the samples from the sample tubes, completing the subsequent dispensing task. After sample aspiration, the sample tubes are picked up from the second sample introduction mechanism 17 and transferred to the sample rack at the transfer mechanism 20. After all sample tubes in the entire sample rack have been introduced, the transfer mechanism 20 carries the sample rack to the second working panel 19, where the pushing mechanism pushes the sample tubes to the second working panel 19 for unloading.

[0026] like Figure 4-9As shown, the second sample introduction mechanism 17 includes a sample placement slot for placing sample tubes; multiple third stopping points are provided along the moving path of the sample placement slot, including a first sample introduction position 21 for introducing regular samples; a second sample introduction position 22 for introducing high-priority samples; a suction position 7 for the sample dispensing mechanism 1 to draw samples from the sample tubes; and a second driving mechanism 23 for driving the sample placement slot to move to the first sample introduction position 21, the second sample introduction position 22, or the suction position 7 respectively, to complete the sample introduction and suction operation of regular samples or high-priority samples.

[0027] It is understood that the higher priority samples in this invention refer to emergency samples or other samples that require pre-arrangement for injection compared to regular samples. The first injection position 21 is located below the sample tube clamping device corresponding to the regular sample injection, facilitating the placement of the clamped sample tube into the sample placement slot at the first injection position 21. The second injection position 22 is located on the operator-facing side of the analyzer, closer to the operator than the first injection position 21, allowing the operator to manually place the higher priority samples directly into the sample placement slot at the second injection position 22, completing the rapid injection of higher priority samples. The sample aspiration position 7 is located inside the analyzer, on the moving path of the sample dispensing mechanism 1, facilitating the analyzer's sample injection and detection operations.

[0028] This invention uses the same sample placement slot with different injection and aspiration positions to complete the injection of both conventional and high-priority samples, thus avoiding the problems of high instrument cost, complex structure, and low efficiency caused by setting up separate injection mechanisms for conventional and high-priority samples.

[0029] The sample placement slot includes a first placement slot 24 for placing ordinary sample tubes and a second placement slot 25 for placing micro-volume blood collection tubes. The first placement slot 24 and the second placement slot 25 are arranged side by side on the second drive mechanism 23. The first placement slot 24 is located on the side closer to the operator.

[0030] This invention, through the arrangement of two placement slots, enables the sample injection mechanism to not only inject samples from ordinary sample tubes but also from micro-volume blood collection tubes. It is understood that the ordinary sample tubes of this invention generally refer to those commonly used for collecting routine or emergency samples from adults; the micro-volume blood collection tubes generally refer to those commonly used for collecting samples from children or other special cases.

[0031] It is understood that the higher priority samples of this utility model include emergency samples or samples collected from children or other special samples using micro-blood collection tubes.

[0032] A squeezing member 26 is rotatably mounted on the side of the first placement slot 24 facing the second placement slot 25; the sample placement slot is slidably mounted on the support frame 27, and an elastic member is provided on the side of the support frame 27 away from the first placement slot 24 of the squeezing member 26. When the second drive mechanism 23 moves the sample placement slot toward the aspiration position 7, the elastic member can compress the squeezing member 26, so that the squeezing member 26 compresses the sample tube in the first placement slot 24, preventing the sample tube in the first placement slot 24 from shaking or deviating from the aspiration position, thereby affecting the aspiration of the sample dispensing mechanism 1.

[0033] Furthermore, the extrusion member 26 includes an extrusion plate 28 rotatably mounted at the bottom of the first placement groove 24; an extrusion block 29 is provided on the top of the extrusion plate 28, and the extrusion block 29 can extend into the first placement groove 24; limiting platforms 30 are provided on both sides of the extrusion block 29, which can limit the distance of the extrusion block 29 extending into the first placement groove 24 to avoid damage to the sample tube by extrusion. It can be understood that the movement distance of the extrusion block 29 facing the second placement groove 25 can be limited by the second placement groove 25. One end of the extrusion block 29 extending into the first placement groove 24 is provided as an arc-shaped convex surface 31. When the sample tube clamping device clamps the sample tube and places it into the first placement groove 24, the arc-shaped bottom surface of the sample tube abuts against the arc-shaped convex surface 31, which can smoothly compress the extrusion block 29 to move, making it easier for the sample tube to be placed into the first placement groove 24.

[0034] The elastic element includes a fixing plate 32 vertically fixed to the support frame 27; a fixing block 33 is horizontally installed on the top side of the fixing plate 32 facing the first placement groove 24; both sides of the fixing block 33 are provided with through holes 34 communicating with the fixing plate 32; a guide rod 35 is slidably sleeved in the through hole 34; a blocking part 36 is fixed at one end of the guide rod 35 near the first placement groove 24, and the other end extends to the outside of the fixing plate 32; when the first placement groove 24 moves close to the blocking part 36, both blocking parts 36 can abut against the extruder 26, thereby squeezing the extruder plate 28 on the first placement groove 24 to rotate into the first placement groove 24, and the extruder block 29 on the extruder plate 28 squeezes the sample tube in the first placement groove 24; a baffle 37 is provided on the guide rod 35 between the fixing block 33 and the fixing plate 32; a spring 38 is sleeved on the guide rod 35 between the baffle 37 and the fixing plate 32.

[0035] When the second drive mechanism 23 moves the sample placement slot towards the sampling position 7, the squeezing plate 28 on one side of the first placement slot 24 can abut against the blocking part 36 on the guide rod 35. After the two abut against each other, the second drive mechanism 23 continues to move the sample placement slot towards the sampling position 7. The blocking part 36 presses against the squeezing plate 28, and the squeezing block 29 on the top of the squeezing plate 28 rotates into the first placement slot 24, thereby pressing the sample tube in the first placement slot 24. Together with the side wall of the first placement slot 24, it clamps the sample tube, preventing the sample tube in the first placement slot 24 from shaking, which would affect the sampling operation of the sample dispensing mechanism 1. Secondly, in this invention, the sample tube in the first placement slot 24 is clamped and fixed from the side by the squeezing member 26 and the elastic member at the sampling position 7. When the sample tube is placed into the sample placement slot from top to bottom at the sampling position, the sample tube is not clamped and fixed, which can avoid the friction between the sample tube wall and the side wall of the sample placement slot when placing the sample tube, thereby avoiding damage to the label on the sample tube.

[0036] Furthermore, rollers 39 are provided on both sides of the bottom of the first placement groove 24. The rollers 39 can rotate along the support frame 27 to reduce the resistance during sliding.

[0037] Furthermore, it also includes a first shaking mechanism 40 and a second shaking mechanism 41; the first shaking mechanism 40 includes a sample tube clamping device, which is set above the first injection position 21, for gripping and shaking ordinary sample tubes. After shaking, the sample tube is placed to the second injection mechanism 17, which carries the sample tube to the aspiration position 7 for aspiration and dispensing; the second shaking mechanism 41 is set on one side of the first shaking mechanism 40, for shaking micro-volume blood collection tubes. The first shaking mechanism 40 grips the micro-volume blood collection tube at the first injection position 21 and places it to the second shaking mechanism 41. After shaking, the second shaking mechanism 41 moves the micro-volume blood collection tube below the first shaking mechanism 40, and the first shaking mechanism 40 grips it to the second injection mechanism 17 for injection.

[0038] It also includes a first reagent compartment 42 and a second reagent compartment 43; the first reagent compartment 42 is located on one side of the first detection pool 3 and is used for storing dye, hemolysin and cleaning solution, etc., and a first reagent aspiration position 11 is provided on the top; the second reagent compartment 43 is located on one side of the third detection pool 5 and is used for storing latex used in CRP / SAA detection, and a second reagent aspiration position 15 is provided on the top.

[0039] It is understood that the sample dispensing mechanism, reagent dispensing mechanism, driving mechanism, shaking mechanism, reagent chamber and detection components of this utility model all use conventional technologies in the field, and will not be described in detail here.

[0040] The above are merely embodiments of this utility model and are not intended to limit this utility model. Any modifications, equivalent substitutions, improvements, etc., made within the spirit and principles of this utility model shall be included within the scope of the claims of this utility model pending approval.

Claims

1. A sample analyzer, characterized in that, include: Sample dispensing mechanism, used for sample aspiration and dispensing; A reagent dispensing mechanism is used for the aspiration and dispensing of reagents. The first detection chamber is used to mix the samples and reagents for DIFF / NRBC / RET detection; The second detection chamber is used to mix the samples and reagents for RBC / PLT / HGB detection; The third detection chamber is used to mix samples and reagents for CRP / SAA detection; The first detection pool, the second detection pool, and the third detection pool are distributed in a straight line along the horizontal direction; The first driving mechanism is used to drive the sample dispensing mechanism and the reagent dispensing mechanism to move linearly in the horizontal direction, so as to complete the aspiration of samples and reagents and the dispensing operation into the detection cell.

2. The sample analyzer according to claim 1, characterized in that, The sample dispensing mechanism along the horizontal straight line is provided with multiple first stopping points, including a sample aspiration position, a first sample dispensing position, a second sample dispensing position and a third sample dispensing position, which are used for sample aspiration and stopping when dispensing samples into the first detection cell, the second detection cell and the third detection cell.

3. The sample analyzer according to claim 1, characterized in that, The reagent dispensing mechanism along the horizontal straight line is provided with multiple second stopping points, including a first reagent aspiration position, a first reagent addition position, a second reagent addition position, a third reagent addition position, and a second reagent aspiration position, which are used for reagent aspiration and stopping when adding reagents to the first detection cell, the second detection cell, and the third detection cell.

4. A sample analyzer according to claim 3, characterized in that, It also includes a first reagent compartment and a second reagent compartment; the first reagent compartment is located on one side of the first detection pool, and a first reagent aspiration position is correspondingly provided on the top; the second reagent compartment is located on one side of the third detection pool, and a second reagent aspiration position is correspondingly provided on the top.

5. A sample analyzer according to claim 1, characterized in that, It also includes a second sample delivery mechanism for transporting sample tubes, including a sample placement slot for placing sample tubes; A support frame, on which the sample placement slot is slidably mounted; multiple third stopping points are provided along the moving path of the sample placement slot, including: The first injection position is used for injecting routine samples; The second injection position is used for injection of higher priority samples; The sampling position is used by the sample dispensing mechanism to draw samples from the sample tube; The second driving mechanism is used to drive the sample placement slot to move to the first injection position, the second injection position, or the aspiration position respectively, to complete the injection and aspiration operation of regular samples or high-priority samples.

6. A sample analyzer according to claim 5, characterized in that, The sample placement slot includes: The first placement slot is for placing ordinary sample tubes; The second placement slot is used for placing micro-volume blood collection tubes; The first placement slot and the second placement slot are arranged side by side on the second drive mechanism.

7. A sample analyzer according to claim 6, characterized in that, An extrusion member is rotatably mounted on the side of the first placement slot facing the second placement slot; an elastic member is provided on the support frame of the extrusion member on the side away from the first placement slot.

8. A sample analyzer according to claim 7, characterized in that, The extrusion component includes an extrusion plate rotatably mounted at the bottom of a first placement groove; an extrusion block is provided on the top of the extrusion plate, and the extrusion block can extend into the first placement groove; limiting platforms are provided on both sides of the extrusion block, which can limit the distance the extrusion block extends into the first placement groove.

9. A sample analyzer according to claim 7, characterized in that, The elastic element includes a fixed plate vertically fixed to a support frame; a fixed block is horizontally installed on the top of the fixed plate facing the first placement slot; both sides of the fixed block are provided with through holes communicating with the fixed plate; a guide rod is slidably sleeved in the through hole; a blocking part is fixed at one end of the guide rod near the first placement slot, and the other end extends to the outside of the fixed plate; a baffle is provided on the guide rod between the fixed block and the fixed plate; a spring is sleeved on the guide rod between the baffle and the fixed plate.

10. A sample analyzer according to claim 5, characterized in that, Also includes: A first shaking mechanism and a second shaking mechanism; the first shaking mechanism includes a sample tube clamping device, which is disposed above the first injection position and is used to grasp and shake ordinary sample tubes; the second shaking mechanism is disposed on one side of the first shaking mechanism and is used to shake micro-volume blood collection tubes.

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