Intimate protection system for preventive shielding of the female urethra against ascending infectious pathogens

Abstract

Utility model protection for an intimate protection system for the preventive shielding of the female urethra against ascending infectious agents, comprising a topically applicable protective agent in the form of a gel, a liquid, a paste or a sticker, characterized in that the composition • contains at least one active ingredient or combination of active ingredients that has antibacterial, antifungal, pH-stabilising or bioadhesive properties, • wherein the composition comprises in particular proanthocyanidins (PAC) in a proportion of 15 to 90%, preferably 30 to 50%, to inhibit the fimbrial binding of pathogenic microorganisms, • Contains D-Mannose in an optional amount to support the adhesion inhibition of Escherichia coli, • Lactic acid to stabilize the pH in the intimate area and to protect the vaginal flora, • Contains lactoferrin and enzymes in optional amounts for antibacterial and antifungal action, • Contains thickeners such as carbomer or xanthan to increase viscosity and adhesive strength, • Contains humectants, especially glycerin, to care for the mucous membrane, • Preservatives such as sodium benzoate, potassium sorbate or chelators (e.g. sodium EDTA) for preservation. • has a saliva-resistant formulation that remains stable on contact with saliva and thus forms a reliable barrier against oral germs, and the composition is designed to effectively shield the female urethra from ascending bacterial and fungal pathogens.

Description

2. Technical area

[0001] The invention relates to the medical-cosmetic prevention of urogenital infections in women. This involves an externally applicable protective system in the form of a liquid, gel, paste, or sticker that is applied to the genital area. The goal is to physically and chemically shield the urethra against ascending infectious pathogens. This protective mechanism is particularly effective during sexual activity (oral, vaginal, anal), but can also be used independently of this as a preventative measure to prevent infection. 3. State of the art

[0002] Urogenital infections, especially cystitis, are often caused by ascending pathogens such as Escherichia coli, Staphylococcus saprophyticus, or Candida species. Existing products such as lubricants, condoms, or antiseptic wash solutions offer only limited protection and often focus solely on mechanical barriers or spot disinfection. These approaches do not comprehensively address sexual (e.g., oral, rectal) or non-sexual infection risks. Furthermore, a reliable, saliva-resistant protective effect during oral contact is lacking. An integrated protection system that is effective both preventively and during sexual activity is not yet available. 4. Object of the invention

[0003] The invention is intended to provide improved protection against ascending infections by: • forms a physical barrier in the intimate area against contact with germs, • has an antibacterial and antifungal effect, • stabilizes the pH value in the intimate area and thus creates a germ-free environment, • remains saliva-resistant upon oral contact, • enables a long shelf life without special storage conditions, • improves the sexual experience by reducing irritation and increasing comfort and • is effective both in sexual activities (oral, vaginal, anal) and in preventative, everyday use 5. Solution of the invention

[0004] The invention consists of a topically applicable protective gel, a protective liquid, a paste, or a protective sticker. The formulation consists of the following main components: • Proanthocyanidins (PAC): 15-90% (preferably 30-50%) to inhibit fimbrial binding of pathogenic germs • D-Mannose (optional): Supports adhesion inhibition in E. coli • Lactic acid: pH stabilization and protection of the vaginal flora • Lactoferrin and enzymes (optional): Antifungal and antibacterial action • Thickener: Carbomer or xanthan for high viscosity and adhesive strength • Humectant: Glycerin to care for the mucous membrane • Preservatives: sodium benzoate, potassium sorbate or chelators (e.g. sodium EDTA) for microbial stability • Saliva-resistant formulation: Ensures durability and protection during oral contact.

[0005] Additionally, the composition may contain chitosan or other bioadhesive polymers to improve adhesion and barrier effectiveness. However, this additive is not a mandatory component of the invention. The invention thus encompasses both compositions with and without chitosan, as long as the protective effect against ascending pathogens is maintained. 6. Packaging and shelf life • Packaging in airless dispensers or airtight individual containers to maintain stability. • Shelf life: at least six months without refrigeration. • Optionally flavored or odor neutralizing for improved comfort. 7. Advantages of the invention • Extended spectrum of protection against urogenital infections through multiactive ingredients • Saliva resistance for safe protection during oral contact • Stabilization of the vaginal flora through pH stabilization • Improve sexual comfort by reducing irritation and physical stress on the mucous membranes • Suitable for use before sexual activities (oral, vaginal, anal) as well as for preventative, everyday protection • Long-lasting and easy to use, even on the go • Optionally enhanced adhesion and barrier effect through chitosan or bioadhesive polymers (without binding to the protective effect) 8. Covered pathogens and effects Pathogen / Risk Coverage by the invention E. coli (most common cause) Inhibition of fimbrial binding (PAC, D-mannose) Staphylococcus saprophyticus PAC and pH stabilization Candida (fungi) Lactic acid, lactoferrin, pH regulation Enterococcus & other intestinal germs PAC, pH regulation pH disturbances caused by sperm / lubricant Lactic acid, pH buffering Spermicide damage to the flora Lactic acid, lactate, pH balance 9. Areas of application • Before oral sex: Protection against germs from the oral flora • Before anal sex: barrier against ascending E. coli • Before vaginal intercourse: Protection against pH disturbances and germ entry • Preventive, regular use independent of sexual activity to reduce the risk of infection

Claims

[1] Utility model protection for an intimate protection system for the preventive shielding of the female urethra against ascending infectious agents, comprising a topically applicable protective agent in the form of a gel, a liquid, a paste or a sticker, characterized by that the composition • contains at least one active ingredient or combination of active ingredients that has antibacterial, antifungal, pH-stabilising or bioadhesive properties, • wherein the composition comprises in particular proanthocyanidins (PAC) in a proportion of 15 to 90%, preferably 30 to 50%, to inhibit the fimbrial binding of pathogenic microorganisms, • Contains D-Mannose in an optional amount to support the adhesion inhibition of Escherichia coli, • Lactic acid to stabilize the pH in the intimate area and to protect the vaginal flora, • Contains lactoferrin and enzymes in optional amounts for antibacterial and antifungal action, • Contains thickeners such as carbomer or xanthan to increase viscosity and adhesive strength, • Contains humectants, especially glycerin, to care for the mucous membrane, • Preservatives such as sodium benzoate, potassium sorbate or chelators (e.g. sodium EDTA) for preservation. • has a saliva-resistant formulation that remains stable on contact with saliva and thus forms a reliable barrier against oral germs, and the composition is designed to effectively shield the female urethra from ascending bacterial and fungal pathogens. [2] Utility model protection according to claim 1, characterized bythat the composition contains chitosan or other bioadhesive polymers in an amount that increases the adhesive strength and barrier effect of the composition towards the skin and mucous membranes, although the presence of these polymers is not mandatory. [3] Utility model protection according to claim 1 or 2, characterized by that the composition is packaged in airless dispensers or airtight unit doses to ensure the stability of the active ingredients and a shelf life of at least six months without refrigeration. [4] Utility model protection according to one of the preceding claims, characterized by that the composition is suitable for use before sexual activities (oral, vaginal, anal) as well as for preventive use in everyday life independent of sexual activities. [5] Utility model protection according to one of the preceding claims, characterized bythat the composition protects against the most common pathogens of urogenital infections, in particular Escherichia coli, Staphylococcus saprophyticus, Candida species, Enterococcus spp. and other intestinal bacteria, through a combination of inhibition of fimbrial binding, pH stabilization and antifungal action. [6] Utility model protection according to one of the preceding claims, characterized by that the composition exerts a preventive protective effect against ascending infectious agents in the urogenital area, in particular by inhibiting the adhesion of pathogenic microorganisms, pH stabilization and antimicrobial and antifungal effects, wherein the protective effect is not limited to the specific pathogens mentioned in claim 4 or active ingredients mentioned in claim 1, but also includes other bacterial or mycotic pathogens that can lead to urogenital infections. [7] Utility model protection according to one of the preceding claims, characterized by that the composition contains active ingredients or combinations of active ingredients which achieve functionally comparable effects to those of the substances mentioned in claim 1, regardless of their chemical nature.