Compound with BRD4-inhibiting effect, manufacturing process therefor and use thereof
DE602020072998T2Active Publication Date: 2026-06-03SHANGHAI HAIHE PHARMACEUTICAL CO LTD
Patent Information
- Authority / Receiving Office
- DE · DE
- Patent Type
- Patents
- Current Assignee / Owner
- SHANGHAI HAIHE PHARMACEUTICAL CO LTD
- Filing Date
- 2020-09-24
- Publication Date
- 2026-06-03
AI Technical Summary
Technical Problem
Current BRD4 inhibitors lack maturity, stability, and safety, necessitating the development of more effective and safer compounds for treating various diseases, particularly cancer and inflammation.
Method used
Development of novel deuterated compounds, stereoisomers, racemates, tautomers, hydrates, solvates, or pharmaceutically acceptable salts with specific structural features targeting BRD4, which exhibit high inhibitory activity and can be used in pharmaceutical compositions for treating diseases mediated by bromodomain proteins.
Benefits of technology
The compounds demonstrate potent BRD4 inhibitory activity, providing a new treatment option for diseases such as cancer and inflammation with improved efficacy and safety profiles.
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