NUCLEAN ACID STRUCTURE
DE602021055391T2Active Publication Date: 2026-06-03CRANEBIO CO LTD CHIYODA-KU +1
Patent Information
- Authority / Receiving Office
- DE · DE
- Patent Type
- Patents
- Current Assignee / Owner
- CRANEBIO CO LTD CHIYODA-KU
- Filing Date
- 2021-07-30
- Publication Date
- 2026-06-03
AI Technical Summary
Technical Problem
Existing techniques for detecting small molecules using DNA origami structures require complex methods such as fluorescent detection or atomic force microscopy, making them cumbersome and less accessible.
Method used
A nucleic acid structure comprising partial nucleic acid structures linked by a Holliday junction, with protruding structures containing nucleic acid aptamers and enzyme split domains, allowing for easy detection of test substances through structural changes.
Benefits of technology
Facilitates easy and sensitive detection of test substances by utilizing structural transitions in the nucleic acid structure, enabling visual or simple absorbance-based detection methods.
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