Diagnosis of congenital heart block

EP4490279A4Pending Publication Date: 2026-06-03HOSPITAL FOR SICK CHILDREN
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Patent Information

Authority / Receiving Office
EP · EP
Patent Type
Applications
Current Assignee / Owner
HOSPITAL FOR SICK CHILDREN
Filing Date
2023-03-10
Publication Date
2026-06-03

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Abstract

A method of diagnosing congenital heart block or risk of congenital heart block in a fetal or infant subject is provided. The method includes the step of detecting in a biological sample obtained from the mother of the subject one or more maternal autoantibodies which bind to target cardiomyocyte proteins of the subject. A kit for use in to detect such maternal autoantibodies is also provided.
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