Method and system for personalised manufacturing of nutritional supplements

Abstract

The invention relates to a method for personalised manufacturing of nutritional supplements, wherein the nutritional supplement is a preparation of N ingredients and wherein N is a integer multiple of 1, the method comprising the following steps: providing at least one carrier having a first defined volume V; providing a first ingredient I1 having a first density dI1 and a first concentration kI1; defining an ingredient amount mI1 of the first ingredient I1 on the basis of a number of parameters, wherein the parameters are customised for the personalised manufacturing process of a preparation; repeating the two last-mentioned steps for the second ingredient I2 and any additional ingredient In, and wherein the manufacturing process comprises filling a total amount of ingredients, and, for each ingredient, a filling amount aln is calculated from the corresponding ingredient amount mIn divided by the corresponding density dIn and the corresponding concentration kIn (mIn / dIn / kIn), and the total of all N filling amounts aln is divided by the defined volume V of the carrier (∑aIn / V).

Description

[0001] Process and system for personalized packaging of food supplements

[0002] The present invention relates to a method and a system for the personalized packaging of dietary supplements and / or dietary supplement mixtures, each according to the preambles of the independent patent claims. The invention further relates to a computer program for implementing the inventive method.

[0003] Technological background

[0004] Dietary supplements, often abbreviated to NEM, are food products intended to supplement the human metabolism with certain nutrients, such as vitamins, vitaminoids, or minerals. They contain these nutrients in concentrated and dosed form, which is why they are usually offered in non-food forms such as tablets, drinking ampoules, powders, effervescent tablets, or capsules. Also well-known and frequently used are antioxidants, essential and / or non-essential amino acids, protein mixtures and / or concentrates or isolates, carnitine, creatine, etc.

[0005] Food supplements are often individually packaged, i.e. a specific food supplement is available in stores as a packaged product in a specific dosage.

[0006] During packaging, a new unit is created by combining different substances or ingredients.

[0007] An unhealthy or unbalanced diet can lead to deficiencies, as can a lack of sun exposure or a purely vegan diet. In these cases, taking a dietary supplement is a suitable supplement or compensation for reaching the recommended daily intake. In certain life situations or for specific risk groups, taking a dietary supplement can also be beneficial. Combination products exist that contain a variety of nutritional supplements, sometimes with different dosages, and are occasionally marketed specifically for specific target groups, such as athletes, women, people 60+, etc.

[0008] What the current forms of administration and distribution of these dietary supplements have in common is that they are not tailored to the individual needs of a specific user. If one wants to take a customized dietary supplement regimen, one must resort to individually packaged supplements and create a customized intake regimen. This results in the need to take a multitude of tablets, ampoules, and capsules. In addition to the obvious impractical aspects of such a flood of capsules, this complexity also leads to insufficient adherence to the dietary supplement regimen, so that the desired health benefits are either not realized at all or only very weakly.

[0009] Furthermore, this type of dosing can pose a health risk, as the end user often ingests a disproportionate amount of fillers and excipients with each dietary supplement. With supplements containing overlapping dietary supplements, it's often difficult for the end user to estimate the actual dose they are consuming.

[0010] There is therefore a need for a process and system for the personalized packaging of food supplements of the type mentioned above, which includes a high degree of customization options, but at the same time, despite comprehensive customization options, it should be ensured that the maximum values ​​prescribed by the health authorities or personally defined are adhered to.

[0011] Description of the invention

[0012] One object of the invention is to overcome at least one of the disadvantages of the known method. A particular object of the invention is to provide a method and system of the type mentioned above that enables the safe and efficient preparation of an individual dietary supplement regimen for an end user. This object is achieved by a method and / or system according to the characterizing part of the independent patent claims.

[0013] One aspect of the present disclosure relates to a method for personalized packaging of dietary supplements, in particular for standardized personalized packaging of dietary supplements.

[0014] A method for personalized packaging of a dietary supplement, wherein the dietary supplement is a preparation of N ingredients and N is an integer multiple of 1, can comprise the following steps: providing at least one carrier with a first defined volume V; providing a first ingredient h with a first density dh and a first concentration kh; defining an ingredient quantity mli of the first ingredient h based on a number of parameters, wherein the parameters are individual for the personalized packaging of a preparation. The two aforementioned steps are carried out for a second ingredient I2 and each further ingredient l n , repeated. The packaging includes filling a total quantity of ingredients N, which per ingredient l n a filling quantity al n determined from the respective amount of ingredients ml ndivided by the respective density dl n and the respective concentration kl n (ml n / dl n / small n ) and the sum of all N filling quantities al n is divided by the defined volume V of the beam ( al n / V).

[0015] The procedure is flexible in terms of the number N of ingredients as well as the selection of the respective ingredients.

[0016] In a special embodiment, the quantity of ingredients is defined ml n based on parameters determined based on consumer input. The definition or determination of ingredient quantities can advantageously be carried out as, or in response to, consumer input. This has the advantage of allowing targeted input to be requested from the consumer. This input can reflect behaviors, preferences, or conditions that lead to individualized packaging.

[0017] Alternatively and / or additionally, the quantity of ingredients ml is defined n based on parameters determined based on a measurement on or in the body. The ingredient quantity can be defined accordingly in response to this measurement. This has the advantage that objective deficiencies can be remedied with an appropriate ingredient composition. It is advantageous if the parameters are indicative of one or more attributes of a consumer for whom the preparation is being created, as this allows the preparation to be specifically tailored.

[0018] Each parameter can be selected as indicative of one or more attributes from a group or subgroup. Such a group can consist of: age, gender, body mass index, eating habits, sleep rhythm, working hours, media consumption, leisure activities, weight, height, skin color, eye color, allergies and / or intolerances, resting heart rate, blood oxygen saturation, cortisol levels, drug and / or stimulant consumption, blood count data, blood sugar, movement data, and / or activity data, e.g., calorie consumption from wearables.

[0019] The ingredients l n N is an integer between 2 and 20, preferably between 7 and 15, and more preferably 11. 9 can also be quite useful. If the number is too small, the desired effect may not occur. If the number of ingredients is too large, the complexity also increases.

[0020] If the filling of the total amount of ingredients l n By incorporating a flavoring, the food supplement becomes more pleasant for the consumer. The added flavor can include flavors such as peppermint, citrus, and vanilla.

[0021] If one or more ingredients l n are chosen so that they correspond to a percentage dose of a recommended daily intake, then the ingredients are well tolerated when ingested and are within recommended amounts.

[0022] In a particular embodiment, the ingredient l nAs a nutrient, a substance can be selected from the group consisting of: cholecalciferol, cyanocobalamin, calcium D-pantothenate, menaquinone-7, black pepper powder, ginseng root powder, turmeric root extract, guarana, L-ascorbic acid, magnesium oxide, and maltodextrin. The ingredients to be selected can generally be derived from amino acids, minerals, plant substances, vitamins, or other substances.

[0023] In a particular embodiment, a probiotic is included as an ingredient n For this purpose, live microorganisms can be included in the preparation. These are considered functional food products. When consumed in sufficient quantities, probiotics can have a health-promoting effect on the host organism.

[0024] Suitable microorganisms may include probiotic bacterial strains of bifidobacteria and / or lactobacilli approved as dietary supplements. Certain yeast strains are also used as probiotics. For use as an ingredient within the meaning of the present invention, the corresponding probiotics can be provided as powders, although lyophilisates are commonly used.

[0025] In a particular embodiment, the ingredient is a prebiotic. Prebiotics can promote the growth and / or survival of a specific microorganism or group of microorganisms in the intestine by supplying them with usable nutrients. Prebiotics also include substances that change the environment so that the environmental parameters are conducive to the growth and maintenance of a specific population of microorganisms. In a particularly preferred embodiment, probiotics and prebiotics are present as ingredients in a synergistic relationship. For example, certain bacterial strains can be selected that are capable of digesting and utilizing certain types of sugar, or that can have a competitive advantage over other microorganisms when supplied with certain types of sugar. In a particularly preferred embodiment, the prebiotics are oligosaccharides.In a preferred embodiment, the carrier is a capsule, in particular a two-part capsule made essentially of gelatin or hydroxypropylmethylcellulose. The capsule can be easily filled with the specified total amount. Consumption by the consumer is also simple, as a capsule is easy to swallow and the gelatin dissolves easily in the body. The capsule is preferably designed so that dissolution only occurs where the effect is greatest. Furthermore, the consumer also has the option of opening the capsule and ingesting the ingredients directly in powder form.

[0026] Alternatively and / or additionally, the carrier can also be provided as a tablet, pill, fruit gum, drinking ampoule, effervescent tablet, and / or in another form. The personalized dietary supplement can also be dispensed in powder form packaged in small pouches or sachets, e.g., as a sealed pouch or sachet. For specific consumers or consumer groups, an oil or liquid can be provided that is intended to be ingested with the carrier. This may result in intended beneficial swallowing or dissolving effects.

[0027] It may also be advantageous to provide several carriers with different ingredients. n This allows a larger dietary supplement range to be covered.

[0028] In a particular embodiment, the ingredient l na substance selected from the group consisting of: biotin, folic acid, niacin, pantothenic acid, riboflavin (vitamin B2), thiamin (vitamin B1), vitamin B6, vitamin B12, vitamin C, vitamin D3, vitamin E, calcium, magnesium, turmeric, ginger, fenugreek, organic green tea sencha, beta-carotene (provitamin A), vitamin K2, iron, selenium, zinc, copper, iodine, chromium, molybdenum, manganese, potassium, fluoride, chloride, phosphorus, lactase, L-arginine, L-glutamine, L-histidine, L-lysine, coenzyme Q10, caffeine, glucosamine, creatine, L-carnitine, taurine, garlic, black pepper, organic maca powder, spirulina, cannabidiol, ginseng, oligomeric proanthocyanidins, guarana, echinacea, green Coffee, barley grass, saffron and L-tryptophan.

[0029] The ingredient may be in a suitable dosage form, e.g. as an extract, salt, hydrolysate, lyophilisate, etc.

[0030] The ingredient may be in a form intended as a food supplement. This may be regulated by law (e.g., by not exerting any pharmacological effect). For the purposes of the present invention, food supplements can be defined as foods intended to supplement the normal diet. They may comprise single or multiple concentrates of vitamins, minerals, or other substances with nutritional or physiological effects and are marketed in metered form.

[0031] Alternatively and / or additionally, the ingredient l nadministered in a form active in the organism at various molecular target structures, for example as a phytopharmaceutical. Phytopharmaceuticals suitable according to the invention are, for example, dried, cut, or whole plant parts, which can originate from one or more plants, for example selected from the group consisting of valerian, bearberry, birch, nettle, goldenrod, St. John's wort, chamomile, lavender, mallow, passionflower, peppermint, sage, senna, licorice, thyme, hawthorn, and / or wormwood.

[0032] Alternatively and / or additionally, the ingredient l n dried, cut or whole parts of a plant approved under food law as tea and / or tea infusion.

[0033] The ingredient is preferably in solid form, particularly preferably as a powder or granulate. In an embodiment according to the invention, various ingredients can be present as a mixture in various forms.

[0034] In another special embodiment, warnings and / or consumption and / or safety instructions are automatically generated for each ingredient starting from a threshold value defined for the respective ingredient. These warnings and / or consumption and / or safety instructions can be printed on the packaging during packaging or provided as a package insert.

[0035] In another special embodiment, minimum and maximum values ​​are defined in advance for each ingredient, so that an individualized composition of a preparation based on the selected attributes automatically falls within these minimum and maximum values.

[0036] In one embodiment, the parameterization comprises further, in particular subjective attributes such as a definition of a label text, one or more colors of a label text and / or a packaging, one or more colors of a carrier and / or a flavoring or aroma substance in the carrier (gelatin or hydroxypropylmethylcellulose) or in the preparation.

[0037] In a particular embodiment, the parameterization comprises a preview function of the preparation, in particular including the packaging, any subjective attributes and / or warnings and / or consumption and / or safety instructions.

[0038] In yet another embodiment, the parameterization comprises a preview function of an individual nutritional table of the ingredients in the preparation, such as quantity, % of the recommended daily intake, etc. In a particular embodiment, the method according to the invention comprises the provision of a data acquisition element. This data acquisition element can, for example, be helpful in measuring and recording data relevant for the parameterization. In a particularly preferred embodiment, the data acquisition element is designed to measure and record at least one physiological parameter of the consumer. For this purpose, the data acquisition element can, for example, be provided with corresponding sensors and / or an analysis unit. Particularly preferably, the data acquisition element is designed to record and measure a physiological parameter by means of a sensor.Suitable sensors for recording physiological parameters include accelerometers, gyroscopes, optical sensors, and / or capacitive sensors. Suitable analytical instruments for a data acquisition element include chromatographic and / or fluorescence-based analytical instruments for analytes, for example, from liquids, especially body fluids such as sweat, blood, saliva, urine, stool, semen, and / or mucous membrane swabs.

[0039] Such data collection elements are suitable for achieving objective measurements beyond subjective individual assessments, which are useful for parameterization and for compiling a customized blend of nutritional supplements. Depending on the area of ​​application, a medical / health focus or a sports focus can be selected. Since the intake of nutritional supplements also has a significant preventative effect, a deficiency or an adaptation to a specific life situation and / or change in life situation can be identified early on by individually compiling appropriate supplements based on a measured value.

[0040] In a particular embodiment, the method according to the invention further comprises the step of storing measured and / or input data used for parameterization in a database profile. This data can be evaluated in a further, particularly preferred step and used as a function of time to calculate a progression. This can be particularly useful for demonstrating any effect or effect of supplementation. Such temporal recording is also suitable, for example, for planning a specific progression, such as training preparation for a competition.In a particularly preferred embodiment, the method according to the invention comprises a step of adapting the personalized packaging of a food supplement by adapting the step of defining an amount of ingredients to a prior definition of a specific amount of ingredients.

[0041] In a particularly preferred embodiment, the method according to the invention comprises a first definition of an ingredient quantity as described above and a second definition of an ingredient quantity based on the previously defined ingredient quantity. This can be particularly useful when a specific deficiency of an ingredient exists, for example, by conducting an initial loading phase after it has been measured or subjectively expected. A loading phase can, for example, provide for a particularly high dosage of a specific ingredient or a mixture of ingredients, which subsequently transitions into a maintenance phase that maintains a specific titer of the relevant ingredients in the body and reduces the dosage.

[0042] Such a first and second definition can also be applied if, for example, a dynamic adaptation to specific life circumstances is required. For example, in an athlete's competition preparation, an ingredient quantity can be adjusted to the respective training phase and dynamically redefined as the training phases change. It is also conceivable to adjust the ingredients based on other life circumstances, such as travel, pregnancy, convalescence, preventative care, palliative care, medication use, withdrawal, circadian rhythm adjustments, military deployments, etc.

[0043] In a particular embodiment, defining an amount of the first ingredient comprises, in addition to first parameters that are individual for the personalized packaging of a preparation, second parameters that are shared with a specific group. These parameters can, for example, include membership in a specific group of people. Parameters that are assigned, for example, to a group of people who pursue a common lifestyle are particularly suitable. In a particularly preferred embodiment, defining an amount of the first ingredient based on a number of parameters comprises first parameters that are individual for the personalized packaging of a preparation and second parameters that are general for a specific group for the packaging of a preparation.Another aspect of the present disclosure relates to a system for personalized packaging of a dietary supplement, wherein the dietary supplement is a preparation of N ingredients. The system comprises an input medium configured to capture a number of parameters, wherein the parameters are unique to the personalized packaging of a preparation, and wherein each parameter is indicative of one or more attributes of a consumer. Furthermore, the system comprises a processor configured to calculate ingredient quantities (ml). n based on the parameters for each ingredient l n a number of N ingredients, and wherein the processor is designed based on the respective density dl n and the respective concentration of each ingredient a filling quantity al nThe system further comprises a filling unit for filling the mixture of all N ingredients in their respective determined filling quantities al n into a number of beams, each with a volume V.

[0044] The parameters can be collected in a context-related and interactive manner. This has the advantage that the parameters can be collected individually and directly, thus generating the greatest possible benefit for the consumer.

[0045] Parameters can be recorded in various modes. For more experienced users, an expert mode can be provided, which provides significantly more information and selection options, but also requires appropriate knowledge to make the selection.

[0046] The process steps can be executed or supported by a computer program. Commands trigger the execution of a program by a computer or computer system. An input mask for entering parameters can be configured so that the parameters are recorded individually, ultimately leading to the personalized preparation of the product.

[0047] A further aspect of the present invention relates to a preparation of a personalized formulation of a dietary supplement. The preparation is particularly preferably obtainable using the method according to the invention mentioned above.

[0048] The preparation comprises a sealable carrier container. The carrier container particularly preferably has a resealable lid. The carrier container can, for example, be in the form of a can and is preferably made of plastic and / or glass.

[0049] A resealable lid can, for example, be connected to the container in a form-fitting manner using a thread.

[0050] Furthermore, the preparation according to the invention comprises a defined plurality of carriers with a first defined volume. Particularly preferably, the carriers are fillable capsules, which have a volume into which a certain, defined amount of ingredients can be filled. The capsules can, for example, be in the form of two-part capsules, which, when connected to one another, enclose a hollow space that serves as the filling volume.

[0051] The preparation according to the invention further comprises a plurality of ingredients with a first density and a first concentration, which together form a total amount of ingredients with a total volume. Particularly preferably, the plurality of ingredients is present as a homogeneous mixture. The homogeneous mixture, or the plurality of ingredients, is evenly distributed among the defined plurality of carriers. The defined plurality of carriers is defined depending on the total volume and the defined volume of the carriers.

[0052] For the purposes of the present invention, the number of carriers can be determined, for example, by the total volume of the majority of ingredients. For example, certain ingredients are available as granules with a specific grain size. Granules are preferably selected to have an ideal surface-to-volume ratio, enabling rapid absorption of the ingredients. Essentially round granule beads also allow for optimal use of the carrier volume.

[0053] The preparation according to the invention is further characterized in that the majority of ingredients are determined based on a number of parameters, wherein the parameters are individual for the personalized packaging of a preparation.

[0054] In a special embodiment, the sealable carrier container is designed to be tamper-proof, so that initial opening remains detectable. This can be ensured, for example, with a sealing strip or a predetermined breaking point, which, once opened, clearly indicates the opened state of the carrier container.

[0055] In a particular embodiment, the carrier container and / or at least one of the defined plurality of carriers comprises a recognition means. The recognition means can, for example, comprise an identification means that makes the preparation and / or an individual carrier clearly assignable to a person, i.e., a consumer who initiated the personalized packaging.

[0056] One advantage of this assignability is that the personalized preparation is actually only taken by the person for whom it was originally intended and for whom it was individually tailored.

[0057] Suitable identification means can be, for example, QR codes or other optically recognizable elements that are machine-readable. Alternatively and / or additionally, electromagnetic identification means, such as RFID tags, can also be provided.

[0058] In a particular embodiment, the preparation according to the invention comprises at least one data acquisition means which is suitable for acquiring consumer-relevant data and making it available for parameterization and the resulting composition of the ingredients.

[0059] Suitable data acquisition devices include wearables, i.e., smartwatches or sensors worn on the body that measure physiological parameters periodically and / or continuously. Suitable data acquisition devices can, for example, be designed to measure a measured value selected from the group consisting of: blood pressure, blood oxygen saturation, heart rate, respiratory rate, pupil dilation, muscle tone, skin tension, skin moisture, and / or skin color. From this, the preparation according to the invention can be used to define suitable parameters that enable a customized combination of ingredients.

[0060] Alternatively and / or additionally, the data acquisition means comprises a means for collecting and evaluating endogenous analytes, i.e., means for obtaining, for example, blood, urine, hair, saliva, secretions, stool, or other body samples and evaluating them for endogenous biomarkers. For example, blood analyses may be suitable for evaluating the composition of fatty acids in the blood, the supply of elements such as the trace elements zinc, copper, selenium, magnesium, manganese, and calcium, the supply of vitamins such as vitamin D3, vitamin E, vitamin A, vitamin B12, vitamin B3, vitamin B5, and / or choline, as well as the supply of essential and non-essential amino acids. Suitable data acquisition means for collecting such analytes are preferably minimally invasive and can be used directly by the consumer without the need for medically trained personnel.

[0061] Suitable data acquisition means that operate on the basis of minimally invasive diagnostics are known to the person skilled in the art and can be selected as required for the desired implementation of the teachings of the invention.

[0062] Devices that enable the consumer to take capillary blood independently and essentially painlessly are particularly suitable.

[0063] In a particular embodiment, the data acquisition means is designed to establish at least one communication interface with a database. The communication interface is preferably designed for wireless data transmission and serves to exchange recorded measured values ​​with the database. The database can be designed to log and evaluate these measured values ​​and store them in a traceable manner over time. The inventive solution, or rather the computer program product described above, can then be designed to compile a corresponding personalized package of food supplements based on this data. It is self-evident to those skilled in the art that all of the described embodiments can be implemented in an inventive embodiment of the present invention, provided they do not explicitly exclude one another.

[0064] In the following, the present invention will now be explained in more detail using specific embodiments and figures, without, however, being limited to these.

[0065] By studying these particular embodiments and figures, a person skilled in the art may discover further advantageous embodiments of the present invention. Description of the figures

[0066] Embodiments of the invention are described with reference to the following figures, wherein like reference symbols denote like or similar parts.

[0067] Fig. 1 : a schematic sequence of steps according to the method according to the invention;

[0068] Fig. 2: a schematic representation of a procedure for the personalized packaging of food supplements;

[0069] Fig. 3: a schematic representation according to the method according to the invention in a further possible embodiment;

[0070] Fig. 4: a schematic representation of a computer system comprising means for carrying out the method according to the invention;

[0071] Figure 5: a schematic implementation of the inventive teaching with a series of data acquisition means;

[0072] Figure 6: a minimally invasive data acquisition device for collecting a blood sample, and

[0073] Figure 7: schematic representation of a preparation of a personalized packaging of a food supplement.

[0074] Implementation of the invention

[0075] Fig. 1 shows a method 10 with a sequence of steps for the personalized packaging of a dietary supplement. In a first step S1, at least one carrier with a first defined volume V is provided. The volume V can be adjusted depending on the carrier or carrier type. In a further step S2, an ingredient h with a first density dh and a first concentration kl 1 is provided. In the following step S4, a definition or determination of an ingredient quantity mli of the first ingredient h takes place based on a number of parameters 4, wherein the parameters 4 are individual for the personalized packaging of a preparation. Steps S2 and S3 are carried out for a second ingredient I2 and each further ingredient l n, according to an ingredient group 2. This is repeated until a preparation can be made from N ingredients, where N is an integer multiple of 1 and is determined based on consumer inputs and / or the parameter 4. In a further step S4, a packaging determination is carried out according to the determined total amount of ingredients N. For each ingredient l n a filling quantity is al n determined from the respective amount of ingredients ml n divided by the respective density dln and the respective concentration kl n (ml n / dl n / small n ) . The sum of all N filling quantities al n is divided by the defined volume V of the beam ( al n / V). Subsequently, in step S5, the ingredients are filled into a respective carrier.

[0076] Example 1

[0077] The following is a purely exemplary compilation of a preparation consisting of N ingredients, where N corresponds to a total of 11 ingredients. Two capsules serve as the carrier, which together form the desired dosage for a consumer.

[0078] Ingredients:

[0079] Cholecalciferol 0.071 g

[0080] Cyanocobalamin 0.192 g

[0081] Calcium D-pantothenate 1,282 g

[0082] Menaquinone-7 2.137 g

[0083] Black pepper powder 5.344 g

[0084] Ginseng radix pulvis 7.5 g

[0085] Turmeric root extract 10.687 g

[0086] Guarana 10.687 g

[0087] L-ascorbic acid 17.1 g

[0088] Magnesium oxide 21,267 g

[0089] Maltodextrin 21,644 g

[0090] This results in a total of 95.774 g. The mixture is mixed and divided into 290 capsules. In this example, each capsule has a volume of 0.68 ml.

[0091] This results in a dietary supplement (DSM) package containing the ingredients magnesium oxide, L-ascorbic acid, turmeric root extract, guarana, ginseng root powder, black pepper powder, menaquinone-7, calcium D-pantothenate, cyanocobalamin, cholecalciferol, and the bulking agent maltodextrin. The capsule shell is made of gelatin.

[0092] In this example, a flavoring agent can also be added to impart a flavor to the capsule, and a capsule color can be defined. In the example above, a batch of red capsules is packaged with the preparation in question. Another batch for the same consumer is packaged with green capsules, for example, and yet another in a different color. This allows the consumer to easily distinguish between different dietary supplements or, for example, different expiration dates.

[0093] By parameterizing the selection of ingredients l n The generation of a list of ingredients is fully automated, including best before date and recommended consumption for the desired dose, in the example above 2 capsules per day.

[0094] According to the recommended intake, an ingredients list would also indicate the following consumption values:

[0095] Pantothenic acid 8.55 mg per daily ration, i.e. 142% of the recommended daily dose Vitamin B12 12.82 mcg per daily ration 513% of the recommended daily dose Vitamin C 114.00 mg per daily ration 142% of the recommended daily dose Vitamin D3 14.25 mcg per daily ration 285% of the recommended daily dose Vitamin K2 28.50 mcg per daily ration 38% of the recommended daily dose Magnesium 85.50 mg per daily ration 23% of the recommended daily dose Turmeric 71.25 mg per daily ration

[0096] Black pepper 35.62 mg per daily ration

[0097] Ginseng 50.00 mg per daily ration

[0098] Guarana 71.25 mg per daily ration

[0099] Based on the selection, safety information would be automatically retrieved from a database, and the following example would generate these safety information: "Caffeine is not recommended for children and pregnant women." "Patients taking anticoagulants should consult their doctor before taking vitamin K supplements."

[0100] Fig. 2 shows a schematic representation of a procedure 20 for the personalized packaging of dietary supplements. A consumer 22 enters parameters 4 relating to a dietary supplement to be customized via an input and / or query medium 21. In a query mode, the information or parameters 4 are transmitted via a network 23, e.g., an intranet or internet, to a packaging system 24, where the personalized packaging of the dietary supplement takes place according to method 10. The customized dietary supplement is created in a filling device 25 and made available to the consumer 22, who receives it via a channel 26.

[0101] Fig. 3 shows a schematic representation of a system 30 for the personalized packaging of dietary supplements for different consumers or users. A first input and / or query unit 31 of a first consumer, a second input and / or query unit 32 of a second consumer, a third input and / or query unit 33 of a third consumer, and further input and / or query units 34 of further consumers are connected to the network 23. Also connected to the network 23 is a packaging determination system 36, which determines individualized dietary supplements for the first, second, third, and further consumers. The data of the determined individualized dietary supplements are transmitted to a filling device 38, where the personalized packaging of the dietary supplement for the respective consumer takes place.

[0102] Fig. 4 shows a schematic representation of a computer system 40 comprising means for carrying out the method according to the invention. The computer system 40 is connected to a network 23, wherein a first input and / or query unit 31, a second input and / or query unit 32, and / or further input and / or query units can be connected to the network. In one possible embodiment, the network 23 can correspond to a known network type. The computer system 40 comprises a computer or server 42 for determining packaging. Furthermore, the computer system 40 has a database 41 connected to the server 42 and also to the network 23. The server 42 comprises an input and output module 43, at least one processor 44, and a memory 45, which can be volatile and / or non-volatile. The server 42 also has a packaging module 46 and a filling module 47.The packaging module 46, with the aid of the processor 44, determines relevant parameters 4 for packaging based on consumer information provided by the input and / or query units 31, 32. For each determined ingredient l. n a filling quantity is al n This is determined from the respective amount of ingredients ml n divided by the respective density dln and the respective concentration kl n (ml n / dl n / small n ) . The sum of all N filling quantities al n is divided by the defined volume V of the beam ( al n / V). The filling module 47 provides all data including the respective defined ingredients l nThe data can be stored in memory 45 and / or database 41. Once stored in database 41, the data can be accessed again later by the same consumer. Furthermore, the stored data can be used to perform comparisons or comparative analyses for different consumers or users. These can be performed using algorithms or artificial intelligence and serve to improve personalized packaging.

[0103] Example 2:

[0104] Example 2 shows an embodiment of interactive parameter input. The parameters are queried using an input and / or query unit.

[0105] To collect suitable parameters, a selection of questions can be used via sequential dialog boxes. Suitable questions for collecting a significant number of parameters according to the invention can be:

[0106] Gender, age group, weight, weight satisfaction, height, issues to be addressed, joint pain, hay fever, food intolerance, fish consumption, fruit and vegetable consumption, sports activity, alcohol consumption, smoking habits, any medications (e.g. blood clotting).

[0107] The questions may require the entry of an exact numerical value (weight in kg, for example), the selection of a simple yes / no answer, a selectable range (18-35 years), or a subjective state of well-being ("I am often tired"). A system, such as the packaging system or packaging determination system, determines and creates a nutritional supplement mix based on the individual information.

[0108] Example 3: This example shows an embodiment of a personalized result.

[0109] A personalized dietary supplement mix is ​​provided with dosage instructions, duration of use, and ingredients. A customized nutritional table lists the ingredients in the preparation, including quantity and percentage of the recommended daily intake. A price can also be specified for each ingredient and for the mix or individual ingredients (the latter not shown). Figure 5 shows an example of a consumer 100 using a variety of different data acquisition devices to collect a series of physiological measurement data that can be used to determine parameters according to the invention.

[0110] It is self-evident to a person skilled in the art that the selection of data acquisition means shown is exemplary and can be combined as desired in an implementation of the inventive teaching.

[0111] The consumer 100 uses, for example, a fitness tracker 101 as a wearable. This fitness tracker 101 is suitable, for example, for detecting and recording movements so that, for example, calorie consumption can be determined. Modern fitness trackers also have means to at least approximately determine blood oxygen saturation and heart rate. The fitness tracker can be a separate element or part of a smartwatch with fitness tracker function. The fitness tracker 101 is particularly preferably integrated into a smartwatch, and the inventive teaching with the above-mentioned computer program product can, for example, have an app implementation that is directly linked to the parameterization of the personalized ingredients. Recorded data can thus be captured more or less in real time and used to compile a personalized package of ingredients.This is particularly suitable for athletes, for example, in preparation for a competition. This allows supplementation to be prepared in relatively small packages that dynamically adapt to the training process and are then repackaged and made available to the consumer accordingly. Integration with a smartphone (106) is particularly suitable. Smartphones (106) are ubiquitous in today's society and are therefore suitable data collection tools for recording personal data.An app connection within the meaning of the present invention can, for example, also provide for the aforementioned parameterization questions to be repeated at periodic intervals, or for the app to ask the consumer further questions at different intervals as a message or prompt, in order to subsequently fine-tune the parameterization and / or dynamically adapt a second preparation. This can, for example, also be done via feedback, so that after a first preparation, a second preparation is compiled based on the feedback from the first preparation.

[0112] Particularly preferably, data is collected and stored in a database 110. The database 110 can be hosted on a server, and access can be restricted to authorized users only through appropriate security measures. The database can also be operatively connected to a machine learning system, which makes individual adjustments to the parameterization based on globally collected metadata, which can be formed, for example, from the entire population of consumers using the inventive teaching.

[0113] In another possible embodiment, consumer 100 also uses smartglasses 104 as a wearable. Smartglasses 104 can, for example, be configured to record pupil size, eye moisture, solar radiation, pupil movements, or other, sometimes autonomic-controlled health parameters and, as described above with the data from the smartwatch, make this data available to database 110 for evaluation.

[0114] These smart glasses 104 can also be designed with suitable sensors to detect, for example, head and body movements using accelerometers and / or gyroscopes.

[0115] The exemplary consumer 100 also has a heart rate monitor 102. Heart rate monitors are used by athletes to accurately measure heart rate during training and / or, for example, to train specifically within a certain heart rate range. Modern heart rate monitors can be connected to smartphones so that the data can be analyzed accordingly. From the heart rate data, for example, conclusions can be drawn about calorie consumption, which are more precise than simply calculating the number of kilometers traveled. This calorie consumption can, for example, serve as an indicator for supplementing with certain ingredients for parameterization according to the present invention.

[0116] The illustrated consumer 100 also has a pedometer 105 in its shoes. The pedometer 105 is capable of detecting and measuring impacts or steps using accelerometers or gyroscopes, respectively, and transmitting them wirelessly to an evaluation unit, in this example a smartphone 106.

[0117] In addition to these externally measured fitness data, a blood sample from the consumer 100 can, for example, be used to determine a specific nutrient level in the body and provide it for parameterizing the ingredients. It has been shown that a blood sample that is as minimally invasive as possible is conducive to better and broader acceptance. In the present example, the consumer 100 therefore uses a minimally invasive blood sampling device 103. The minimally invasive blood sampling device 103 can be designed to collect just a sufficient amount of capillary blood from the consumer 100, which is suitable for determining the desired blood values, which are used as parameters for defining the ingredient quantities.

[0118] A suitable device for minimally invasive blood sampling 103 is shown as an example in Figure 6. The minimally invasive blood sampling device 103 comprises a body module that serves as a carrier for the functional units and as a support for the blood sampling site. The upper arm has proven particularly suitable as a blood sampling site because it is largely accessible and comparatively less sensitive to pain. The thigh, buttocks, or calf are also suitable. For the application shown, however, the upper arm is intended, which is perforated by an arrangement of microneedles 103.2, and blood withdrawal from the capillaries is stimulated by generating a vacuum. To collect the blood, a sampling container 103.4 is guided by means of a slide 103.3 via a sealing nipple (not shown) in operative connection to the vacuum, so that blood is withdrawn. Preferably, a small and just sufficient amount of blood is collected.The filled collection container 103.4' can be taken or sent to a suitable laboratory for analysis purposes. The collection container can contain suitable reagents and / or buffers for stabilizing and / or fixing the blood sample.

[0119] Figure 7 shows a preparation according to the invention as it can be obtained from carrying out a process according to the invention.

[0120] The preparation comprises a carrier container 200, which is designed to accommodate a plurality of carriers 201. In the present example, the carriers 201 are designed as capsules, which consist of a first carrier half 20T and a second carrier half 201". The capsules 201 are made of gelatin in the example, and the two carrier halves 20T, 201" are pushed into one another and locked together, so that they form an internal volume, which is designed to accommodate an ingredient mixture 210. In the present example, the ingredient mixture 210 is designed as a powder and / or granulate, but an ingredient mixture 210 which consists at least partially of liquid and / or is a dispersion is also conceivable, e.g.a gel and / or a solid, an oil and / or an aqueous solution, an alcohol, an ester or a combination thereof, depending on the specific composition of the ingredients and suitable carrier media for the ingredients, which are filled into the corresponding carrier 201.

[0121] In the present example of Figure 7, alternative carriers 201.2, 201.3, 201.4 are also shown. A special carrier 201.2 can, for example, be identified by a special color in the carrier container 200. The special carrier 201.2 can have a different ingredient composition 210 or can merely be differentiated from the others by color. In an embodiment according to the invention, a plurality of such special carriers 201.2 can be provided in the carrier container 200. It is advantageous, for example, if fats are also taken for certain vitamins in addition to water, since these vitamins are essentially fat-soluble. Special carriers 201.2 can then be provided, for example, to provide a fat supply, in the form of, for example, gelatin-coated oil capsules or similar administration means known to those skilled in the art.

[0122] In the present example, a probe carrier 201.3 is also provided. The probe carrier 201.3 encloses a probe within its interior, which is suitable for collecting measured values ​​from the user's intestine. Referring again to Figure 5, the consumer 100 also uses a probe 107, which measures, for example, certain intestinal parameters, such as the pH value, or simply the motility of the intestine. The motility of the intestine can be easily measured, for example, using a probe that essentially passes through the intestine and serves to record the period between ingestion of the probe and its excretion. Particularly preferably, the probe is designed for this purpose such that it essentially passes through the intestine easily and is easily recognizable in the stool.

[0123] Capsule endoscopic analyses of the intestine are also conceivable, for example to detect inflammation sites or other changes in the intestine and to determine corresponding parameters for the packaging of ingredients according to the present invention.

[0124] In the present example, identification carriers 201.4 are also provided. These identification carriers 201.4 can have optically recognizable elements on their surface, for example in the form of a printed capsule label 212. The capsule label can be provided, for example, with markers that can lead to information reproduction via optical detection devices. Suitable markers are recognizable by optical cameras, for example, those of smartphones, similar to QR codes, and lead to the reproduction of information via access to a database.

[0125] It is also possible for all carriers 201 in a carrier container according to the invention to be provided with such markings 212. These capsules can be clearly and unambiguously assigned to the personalized packaging according to the present invention even after they have been removed from the carrier container 200, so that the consumer can always be sure of using specific capsules and can rely on the capsules containing the ingredient mixtures they have compiled using the parameterization.

[0126] In the present example, the container 200 is closed by a container lid 203. The container lid 203 also has an identification means 204. The identification means 204 can, for example, be a machine-readable identification means 204. Passive tags, such as passive RFID tags, which can be activated and read using an RFID reader, are particularly suitable. This can serve, on the one hand, the logistics of the corresponding packaging, i.e., the correct delivery of the personalized packaging to the correct consumer 100, but alternatively, it can also be used by the consumer to identify their specially prepared mixture.

[0127] In the present example, the container lid 203 also has a first part 205.1 of a tamper-evident device. A second part 205.2 of the tamper-evident device is attached to the edge of the container 200 that is to be brought into operative connection with the lid 203. In a simple embodiment, this tamper-evident device 205.1, 205.2 is designed as a seal, which tears when the container is opened for the first time and the lid 203 is removed, thus making the tampering of the container obvious.

[0128] In the present example, the container 200 according to the invention also has a flavor element 207 inserted or simply inserted into the container. The flavor element 207 serves to flavor the capsules with a specific flavor. Surprisingly, it has been shown that the capsules can be individually flavored and that it is sufficient to insert a flavor element 207, which is, for example, impregnated with a specific flavoring agent, into the container 200, and that the capsules are able to absorb this flavor via the gelatin. Suitable flavoring agents can, for example, impart the flavor of peppermint, citrus fruit, lavender, etc., to the capsules, depending on the consumer's wishes and corresponding parameterization.

[0129] For unambiguous and unambiguous identification of the container 200 and its contents, the container 200 also has a container label 202, which in turn is equipped with a label identifier 206. This label identifier 206 can again have a machine-readable optical element, for example, a QR code or optical elements that are transferred from an app into a specific virtual environment via linking or augmented reality. The present disclosure shows a method and system for the personalized packaging of dietary supplements. It goes without saying that numerous other embodiments are conceivable for a person skilled in the art based on the exemplary embodiments described. List of Reference Symbols

[0130] S1 first step, providing carrier

[0131] S2 second step, providing ingredient

[0132] S3 third step, define, determine

[0133] S4 fourth step, assembly

[0134] S5 fifth step, filling

[0135] 2 ingredients

[0136] 4 parameters

[0137] 21 Input and / or query medium

[0138] 22 consumers

[0139] 23 Network

[0140] 24 assembly system

[0141] 25 Filling device

[0142] 26 channels

[0143] 30 systems

[0144] 31 -34 input and / or query units

[0145] 36 Packaging determination system

[0146] 38 Filling device

[0147] 40 computer system

[0148] 42 computers or servers

[0149] 41 Database

[0150] 43 Input and output module

[0151] 44 processor

[0152] 45 storage

[0153] 46 Assembly module

[0154] 47 Filling module

[0155] 100 consumers with different data collection tools

[0156] 101 Wearable, e.g. fitness tracker

[0157] 102 Wearable, e.g. heart rate monitor 103 Minimally invasive blood sampling device

[0158] 103.1 Body module

[0159] 103.2 Needles

[0160] 103.3 Slider

[0161] 103.4 Withdrawal container

[0162] 103.4' filled withdrawal container

[0163] 103.5 Trigger

[0164] 104 wearables, e.g. smart glasses

[0165] 105 Wearable, e.g. pedometer

[0166] 106 smartphones

[0167] 107 probe

[0168] 200 carrier containers

[0169] 201 carriers

[0170] 201 ' first beam half

[0171] 201 ” second beam half

[0172] 201.2 special carrier

[0173] 201.3 Probe carrier

[0174] 201.4 License plate holder

[0175] 202 label

[0176] 203 lid

[0177] 204 means of identification

[0178] 205.1 Tamper protection / seal, first part

[0179] 205.2 Tamper protection / Seal, second part

[0180] 206 label markings

[0181] 207 Aroma element

[0182] 210 ingredient blend

[0183] 211 probe

[0184] 212 Capsule label N Number of ingredients

[0185] V Volume al n Filling quantity mln Amount of ingredients dln Density kln Concentration

Claims

Patent claims 1. A method for personalized packaging of a food supplement, wherein the food supplement (6) is a preparation of N ingredients and N is an integer multiple of 1, comprising the steps: a) providing (S1) at least one carrier (5) with a first defined volume V; b) providing (S2) a first ingredient with a first density dh and a first concentration kh; c) defining (S3) an ingredient quantity mh of the first ingredient based on a number of parameters (4), wherein the parameters (4) are individual for the personalized packaging of a preparation; d) repeating steps b) and c) for a second ingredient I2 and each further ingredient l n , and wherein the packaging (S4) comprises filling (S5) a total amount of ingredients, which per ingredient l n a filling quantity al ndetermined from the respective amount of ingredients ml n divided by the respective density dl n and the respective concentration kl n (ml n / dl n / small n ) and the sum of all N filling quantities al n is divided by the defined volume V of the beam ( al n / V).

2. A method according to claim 1, wherein defining the amount of ingredient ml n based on parameters (4) which are determined depending on a consumer input.

3. A method according to any one of claims 1 or 2, wherein the parameters are indicative of one or more attributes of a consumer for whom the preparation is prepared.

4. Method according to claim 1, wherein each parameter is indicative of one or more attributes selected from the group consisting of: age, gender, body mass index, eating habits, sleep rhythm, working hours, Media consumption, leisure activities, weight, height, skin colour, eye colour, allergies and / or intolerances, resting heart rate, blood oxygen saturation, cortisol levels, drug and / or stimulant consumption, blood count data, blood sugar, movement data and / or activity data (e.g. calorie consumption) from wearables.

5. A process according to claim 1, wherein N is an integer between 2 and 20, preferably between 7 and 15, more preferably 11.

6. A method according to claim 1, wherein the filling of the total amount of ingredients N takes into account a flavor addition.

7. A process according to claim 1, wherein one or more ingredients l n be chosen so that they correspond to a percentage dose of a recommended daily intake.

8. A process according to claim 1, wherein the ingredients l nselected from the group consisting of: Cholecalciferol, Cyanocobalamin, Calcium-D-pantothenate, Menaquinone-7, Black pepper powder, Ginseng radix pulvis, Turmeric root extract, Guarana, L-Ascorbic acid, Magnesium oxide, Maltodextrin, Biotin, Folic acid, Niacin, Pantothenic acid, Riboflavin (Vitamin B2), Thiamin (Vitamin B1), Vitamin B6, Vitamin B12, Vitamin C, Vitamin D3, Vitamin E, Calcium, Magnesium, Curcuma, Ginger, Fenugreek, Green tea, Beta-carotene (Provitamin A), Vitamin K2, Iron, Selenium, Zinc, Copper, Iodine, Chromium, Molybdenum, Manganese, Potassium, Fluoride, Chloride, Phosphorus, Lactase, L-Arginine, L-Glutamine, L-Histidine, L-Lysine, Coenzyme Q10, Caffeine, Glucosa- min, creatine, L-carnitine, taurine, garlic, black pepper, maca, spirulina, cannabidiol, ginseng, oligomeric proanthocyanidins, guarana, echinacea, green coffee, barley grass, saffron and L-tryptophan, especially each in a form administered as a food supplement.

9. A method according to claim 1, wherein a probiotic is used as ingredients l n is used.

10. A process according to claim 1, wherein the carrier is a capsule, preferably comprising gelatin. Method according to claim 1, wherein the carrier is provided as a tablet, pill, fruit gum, drinking ampoule and / or effervescent tablet. A system for personalized packaging of a dietary supplement, wherein the dietary supplement is a preparation of N ingredients, comprising: an input medium (21, 31-34) configured to capture a number of parameters (4), wherein the parameters (4) are individual for the personalized packaging of a preparation and wherein each parameter (4) is indicative of one or more attributes of a consumer; a processor (44) configured to calculate ingredient quantities mln based on the parameters for each ingredient l na number of N ingredients, and wherein the processor (44) is designed based on the respective density dl n and the respective concentration kl n each ingredient a filling quantity al n and a filling unit (25, 38) for filling the mixture of all N ingredients in their respective determined filling quantity al ninto a number of carriers, each with a volume V. System according to claim 12, wherein the acquisition of the parameters (4) is context-related and interactive. Computer program, comprising commands which, when the program is executed by a computer, cause the computer to carry out steps of the method according to one of claims 1 to 5. Computer program according to claim 14, wherein an input mask is configured for the acquisition of parameters and the parameters define the personalized packaging of the preparation. A preparation of a personalized packaging of a dietary supplement, in particular obtainable with a method according to claim 1, comprising a. a sealable carrier container; b. a defined plurality of carriers with a first defined volume V; c. a plurality of ingredients with a first density dh and a first concentration kli, which together form a total amount of ingredients with a total volume and, in particular as homogeneous mixtures, are evenly distributed over the defined plurality of carriers, wherein the defined plurality of carriers is defined as a function of the total volume and the defined volume V; characterized in that the plurality of ingredients are determined on the basis of a number of parameters (4), wherein the parameters (4) are individual for the personalized packaging of a preparation.

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