Whitening oral care compositions free of hydrogen peroxide

Abstract

Described herein are oral care compositions comprising an oxidizing agent comprising potassium caroate, a carrier comprising a polymeric fluid, an adhesion agent and a flavorant; wherein the oxidizing agent is substantially free, optionally free, of a peroxide source.

Description

WHITENING ORAL CARE COMPOSITIONS FREE OF HYDROGEN PEROXIDECROSS-REFERENCE TO RELATED APPLICATIONS

[0001] This application claims the benefit of priority from U.S. Patent Application No. 63 / 586,212, filed September 28, 2023, titled Oral Care Compositions, the content of which is hereby incorporated herein in its entirety for all purposes.BACKGROUND

[0002] Oral care products including whitening agents are often utilized to whiten teeth. For example, conventional oral care products include hydrogen peroxide and are often utilized to whiten the surfaces of teeth. While oral care products including hydrogen peroxide have proven to be effective for whitening teeth, the utilization of hydrogen peroxide is limiting. Therefore, the need exists for an improved whitening composition.BRIEF SUMMARY

[0003] Embodiments of the invention provide a whitening composition comprising: an oxidizing agent comprising potassium caroate; a earner comprising a polymeric fluid; an adhesion agent; a flavorant; and wherein the oxidizing agent is free of hydrogen peroxide.

[0004] Embodiments of the present invention include a whitening composition comprising: a first whitening component comprising: an oxidizing agent comprising potassium caroate; a carrier comprising a polymeric fluid; a flavorant; a second whitening component comprising: an alkali component; and wherein the first whitening component and the second whitening component are present in a weight ratio ranging from about 1:2 to about 2:1.

[0005] In some embodiments, the present invention includes a whitening composition comprising: an oxidizing agent comprising potassium caroate; a carrier comprising a polymeric fluid; a first flavorant comprising at least one of sucralose, sodium saccharin, and combinations thereof; and a second flavorant comprising a sensate.

[0006] In some embodiments, the present invention includes a method of whitening a tooth comprising: a) dispensing an amount of the whitening composition according to any of the previous whitening compositions onto an applicator; b) contacting the whitening composition on the applicator with the tooth for a period of treatment time.

[0007] In some embodiments, the present invention a method of manufacture of a whitening product comprising: a) blending together an oxidizing agent comprising potassium caroatc, a carrier comprising a polymeric fluid, an adhesion agent, and a flavorant to form a whitening composition; and b) of distributing a volume of the whitening composition in a packaging to form the whitening product, whereby the whitening composition in the packaging is free of hydrogen peroxide.

[0008] A list of non-limiting example embodiments is provided below.In accordance with an embodiment 1, provided is a whitening composition comprising: an oxidizing agent comprising potassium caroate; a carrier comprising a polymeric fluid; an adhesion agent; a flavorant; and wherein the oxidizing agent is substantially free, optionally free, of hydrogen peroxide.

[0009] In accordance with an embodiment 2, provided is the whitening composition according to embodiment 1, wherein the oxidizing agent is present in an amount ranging from about 0.1 wt. % to about 15 wt. % based on the total weight of the whitening composition.

[0010] In accordance with an embodiment 3, provided is the whitening composition according to any one of embodiments 1 to 2, wherein the potassium caroate is present in an amount ranging from about 0.1 wt. % to about 5.0 wt. % based on the total weight of the whitening composition.

[0011] In accordance with an embodiment 4, provided is the whitening composition according to any one of embodiments 1 to 3, wherein the whitening composition is free of hydrogen peroxide.

[0012] In accordance with an embodiment 5, provided is the whitening composition according to any one of embodiments 1 to 4, wherein the polymeric fluid comprises silicone fluid.

[0013] In accordance with an embodiment 6, provided is the whitening composition according to embodiment 5, wherein the silicone fluid is present in an amount ranging from about 20 wt. % to about 60 wt. % based on the total weight of the whitening composition.

[0014] In accordance with an embodiment 7, provided is the whitening composition according to any one of embodiments 1 to 6, wherein the adhesion agent is present in an amount ranging from about 10.0 wt. % to about 40 wt. % based on the total weight of the whitening composition.

[0015] In accordance with an embodiment 8, provided is the whitening composition according to any one of embodiments 1 to 7, wherein the adhesion agent comprises one or more of polyvinyl pyrrolidone, a polyether, and trimethylated silica treated with dimethyl siloxane.

[0016] In accordance with an embodiment 9, provided is the whitening composition according to embodiment 8, wherein the polyether comprises one or more of polyethylene glycol, polyethylene glycol-polypropylene glycol copolymer, and polyoxypropylene-polyoxyethylene block copolymer.

[0017] In accordance with an embodiment 10, provided is the whitening composition according to any one of embodiments 8 to 9, wherein the polyvinyl pyrrolidone is present in an amount ranging from about 1.0 wt. % to about 7.0 wt. % based on the total weight of the whitening composition.

[0018] In accordance with an embodiment 11, provided is the whitening composition according to any one of embodiments 8 to 10, wherein the polyether is present in an amount ranging from about 30.0 wt. % to about 50.0 wt. % based on the total weight of the whitening composition.

[0019] In accordance with an embodiment 12, provided is the whitening composition according to any one of embodiments 1 to 11, further comprising fumed silica.

[0020] In accordance with an embodiment 13, provided is the whitening composition according to embodiment 12, wherein the fumed silica is present in an amount ranging from about 1.0 wt. % to about 5.0 wt. % based on the total weight of the whitening composition.

[0021] In accordance with an embodiment 14, provided is the whitening composition according to any one of embodiments 1 to 11, further comprising sodium tripolyphosphate.

[0022] In accordance with an embodiment 15, provided is the whitening composition according to embodiment 14, wherein the sodium tripolyphosphate is present in an amount ranging from about 1.0 wt. % to about 4.0 wt. % based on the total weight of the whitening composition.

[0023] In accordance with an embodiment 16, provided is the whitening composition according to any one of embodiments 1 to 15, wherein the flavorant comprises one or more of sodium saccharin, sucralose, and a sensate.

[0024] In accordance with an embodiment 17, provided is the whitening composition according to any one of embodiments 1 to 16, wherein the flavorant is present in an amount ranging from about 0.1 wt. % to about 2.0 wt. % based on the total weight of the whitening composition.

[0025] In accordance with an embodiment 18, provided is a whitening composition comprising:a first whitening component comprising: an oxidizing agent comprising potassium caroatc; a carrier comprising a polymeric fluid; a flavorant; a second whitening component comprising: an alkali component; and wherein the first whitening component and the second whitening component are present in a weight ratio ranging from about 1:3 to about 3:1.

[0026] In accordance with an embodiment 19, provided is the whitening composition according to embodiment 18, wherein the first whitening component is substantially free, optionally free, of hydrogen peroxide.

[0027] In accordance with an embodiment 20, provided is the whitening composition according to any one of embodiments 18 to 19, wherein the second whitening component is substantially free, optionally free, of hydrogen peroxide.

[0028] In accordance with an embodiment 21, provided is the whitening composition according to any one of embodiments 18 to 20, wherein the whitening composition has a pH ranging from about 7 to about 9.

[0029] In accordance with an embodiment 22, provided is the whitening composition according to any one of embodiments 18 to 21, wherein the polymeric fluid comprises silicone fluid.

[0030] In accordance with an embodiment 23, provided is the whitening composition according to embodiment 22, wherein the silicone fluid is present in an amount ranging from about 10.0 wt. % based on the total weight of the first whitening component.

[0031] In accordance with an embodiment 24, provided is the whitening composition according to any one of embodiments 16 to 23, wherein the first whitening component further comprises an adhesion agent is present in an amount ranging from about 10.0 wt. % to about 40.0 wt. % based on the total weight of the first whitening component.

[0032] In accordance with an embodiment 25, provided is the whitening composition according to embodiment 24, wherein the adhesion agent comprises one or more of polyvinyl pyrrolidone and a polyether.

[0033] In accordance with an embodiment 26, provided is the whitening composition according to embodiment 25, wherein the polyether comprises one or more of polyethylene glycol,polyethylene glycol-polypropylene glycol copolymer, and polyoxypropylene-polyoxyethylene block copolymer.

[0034] In accordance with an embodiment 27, provided is the whitening composition according to any one of embodiments 25 to 26, wherein the polyvinyl pyrrolidone is present in an amount ranging from about 1.0 wt. % to about 4.0 wt. % based on the total weight of the first whitening component.

[0035] In accordance with an embodiment 28, provided is the whitening composition according to any one of embodiments 25 to 27, wherein the polyether is present in an amount ranging from about 15.0 wt. % to about 25.0 wt. % based on the total weight of the first whitening component.

[0036] In accordance with an embodiment 29, provided is the whitening composition according to any one of embodiments 18 to 28, further comprising fumed silica.

[0037] In accordance with an embodiment 30, provided is the whitening composition according to embodiment 29, wherein the fumed silica is present in an amount ranging from about 1.0 wt. % to about 3.0 wt. % based on the total weight of the whitening composition.

[0038] In accordance with an embodiment 31, provided is the whitening composition according to any one of embodiments 18 to 30, further comprising sodium tripolyphosphate.

[0039] In accordance with an embodiment 32, provided is the whitening composition according to embodiment 31, wherein the sodium tripolyphosphate is present in an amount ranging from about 1.0 wt. % to about 2.0 wt. % based on the total weight of the first whitening component.

[0040] In accordance with an embodiment 33, provided is the whitening composition according to any one of embodiments 18 to 32, wherein the flavorant comprises one or more of sodium saccharin, sucralose, and a sensate.

[0041] In accordance with an embodiment 34, provided is the whitening composition according to any one of embodiments 18 to 33, wherein the flavorant is present in an amount ranging from about 0.1 wt. % to about 2.0 wt. % based on the total weight of the first whitening component.

[0042] In accordance with an embodiment 35, provided is the whitening composition according to any one of embodiments 18 to 34, wherein the alkali component comprises one or more of sodium bicarbonate and sodium carbonate.

[0043] In accordance with an embodiment 36, provided is the whitening composition according to embodiment 35, wherein the alkali component comprises sodium bicarbonate and sodium carbonate in a weight ratio ranging from about 6:1 to about 12:1.

[0044] In accordance with an embodiment 37, provided is the whitening composition according to embodiment 36, wherein the alkali component comprises sodium bicarbonate and sodium carbonate in a weight ratio ranging from about 8:1 to about 9:1.

[0045] In accordance with an embodiment 38, provided is the whitening composition according to any one of embodiments 18 to 37, wherein the weight ratio of the first whitening component and the second whitening component is about 1:1.

[0046] In accordance with an embodiment 39, provided is the whitening composition according to any one of embodiments 18 to 38, wherein the second component further comprises a liquid carrier and a thickener.

[0047] In accordance with an embodiment 40, provided is the whitening composition according to embodiment 39, wherein the liquid carrier comprises water and the thickener comprises carboxymethylcellulose sodium.

[0048] In accordance with an embodiment 41, provided is the whitening composition according to any one of embodiments 39 to 40, wherein the liquid carrier is present in an amount ranging from about 10.0 wt. % to about 99.0 wt. % based on the total weight of the second whitening component

[0049] In accordance with an embodiment 42, provided is the whitening composition according to any one of embodiments 39 to 41, wherein the thickener is present in an amount ranging from about 1.0 wt. % to about 8.0 wt. % based on the total weight of the second whitening component.

[0050] In accordance with an embodiment 43, provided is a whitening composition comprising: an oxidizing agent comprising potassium caroate; a carrier comprising a polymeric fluid; a first flavorant comprising at least one of sucralose, sodium saccharin, and combinations thereof; and a second flavorant comprising a sensate.

[0051] In accordance with an embodiment 44, provided is the whitening composition according to embodiment 43, wherein the oxidizing agent is present in an amount ranging from about 0.1 wt. % to about 15 wt. % based on the total weight of the whitening composition.

[0052] In accordance with an embodiment 45, provided is the whitening composition according to any one of embodiments 43 to 44, wherein the potassium caroate is present in an amountranging from about 0.1 wt. % to about 5.0 wt. % based on the total weight of the whitening composition.

[0053] In accordance with an embodiment 46, provided is the whitening composition according to any one of embodiments 43 to 45, wherein the oxidizer is substantially free, or free, of hydrogen peroxide.

[0054] In accordance with an embodiment 47, provided is the whitening composition according to any one of embodiments 43 to 46, wherein the polymeric fluid comprises silicone fluid.

[0055] In accordance with an embodiment 48, provided is the whitening composition according to embodiment 47, wherein the silicone fluid is present in an amount ranging from about 20 wt. % to about 60 wt. % based on the total weight of the whitening composition.

[0056] In accordance with an embodiment 49, provided is the whitening composition according to any one of embodiments 43 to 48, wherein the adhesion agent is present in an amount ranging from about 10.0 wt. % to about 40 wt. % based on the total weight of the whitening composition.

[0057] In accordance with an embodiment 50, provided is the whitening composition according to any one of embodiments 43 to 49, wherein the adhesion agent comprises one or more of polyvinyl pyrrolidone and a polyether.

[0058] In accordance with an embodiment 51, provided is the whitening composition according to embodiment 50, wherein the polyether comprises one or more of polyethylene glycol, polyethylene glycol-polypropylene glycol copolymer, and polyoxypropylene-polyoxyethylene block copolymer.

[0059] In accordance with an embodiment 52, provided is the whitening composition according to any one of embodiments 50 to 51, wherein the polyvinyl pyrrolidone is present in an amount ranging from about 1.0 wt. % to about 7.0 wt. % based on the total weight of the whitening composition.

[0060] In accordance with an embodiment 53, provided is the whitening composition according to any one of embodiments 50 to 52, wherein the polyether is present in an amount ranging from about 30.0 wt. % to about 50.0 wt. % based on the total weight of the whitening composition.

[0061] In accordance with an embodiment 54, provided is the whitening composition according to any one of embodiments 43 to 53, further comprising fumed silica.

[0062] In accordance with an embodiment 55, provided is the whitening composition according to embodiment 54, wherein the fumed silica is present in an amount ranging from about 1.0 wt. % to about 5.0 wt. % based on the total weight of the whitening composition.

[0063] In accordance with an embodiment 56, provided is the whitening composition according to any one of embodiments 43 to 55, further comprising sodium tripolyphosphate.

[0064] In accordance with an embodiment 57, provided is the whitening composition according to embodiment 56, wherein the sodium tripolyphosphate is present in an amount ranging from about 1.0 wt. % to about 4.0 wt. % based on the total weight of the whitening composition.

[0065] In accordance with an embodiment 58, provided is the whitening composition according to any one of embodiments 43 to 57, wherein the flavorant comprises one or more of sodium saccharin, sucralose, and a sensate.

[0066] In accordance with an embodiment 59, provided is the whitening composition according to any one of embodiments 43 to 58, wherein the flavorant is present in an amount ranging from about 0.1 wt. % to about 2.0 wt. % based on the total weight of the whitening composition.

[0067] In accordance with an embodiment 60, provided is the whitening composition according to any one of embodiments 1 to 59, wherein the whitening composition is a gel.

[0068] In accordance with an embodiment 61 , provided is a method of whitening a tooth comprising applying a composition according to any foregoing embodiment to a tooth surface of a subject in need thereof.

[0069] In accordance with an embodiment 62, provided is the method according to embodiment 61, wherein the composition is applied using an applicator.

[0070] Further areas of applicability of the present invention will become apparent from the detailed description provided hereinafter. It should be understood that the detailed description and specific examples, while indicating preferred embodiments of the invention, are intended for purposes of illustration only and are not intended to limit the scope of the invention.DETAILED DESCRIPTION

[0071] The following description of the preferred embodiment(s) is merely exemplary in nature and is in no way intended to limit the invention, its application, or uses.

[0072] As used throughout, ranges are used as shorthand for describing each and every value that is within the range. Any value within the range can be selected as the terminus of the range.In addition, all references cited herein are hereby incorporated by referenced in their entireties. In the event of a conflict in a definition in the present disclosure and that of a cited reference, the present disclosure controls.

[0073] Unless otherwise specified, all percentages and amounts expressed herein and elsewhere in the specification should be understood to refer to percentages by weight. The amounts given are based on the active weight of the material.

[0074] The terms “comprising,” “having,” and “including” are used in their open, non-limiting sense.

[0075] The compositions and methods of the present disclosure can comprise, consist of, or consist essentially of the essential elements and limitations of the disclosure described herein, as well as any additional or optional ingredients, components, or limitations described herein or otherwise useful.

[0076] The description of illustrative embodiments according to principles of the present invention is intended to be read in connection with the accompanying drawings, which are to be considered part of the entire written description. In the description of embodiments of the invention disclosed herein, any reference to direction or orientation is merely intended for convenience of description and is not intended in any way to limit the scope of the present invention.

[0077] Unless otherwise specified, all percentages and amounts expressed herein and elsewhere in the specification should be understood to refer to percentages by weight. The amounts given are based on the active weight of the material.

[0078] Additionally, all numerical values are “about” or “approximately” the indicated value, and take into account experimental error and variations that would be expected by a person having ordinary skill in the art. It should be appreciated that all numerical values and ranges disclosed herein are approximate values and ranges, whether “about” is used in conjunction therewith. It should also be appreciated that the term “about,” as used herein, in conjunction with a numeral refers to a value that may be ±0.01% (inclusive), ±0.1% (inclusive), ±0.5% (inclusive), ±1% (inclusive) of that numeral, ±2% (inclusive) of that numeral, ±3% (inclusive) of that numeral, ±5% (inclusive) of that numeral, ±10% (inclusive) of that numeral, or ±15% (inclusive) of that numeral. It should further be appreciated that when a numerical range is disclosed herein, any numerical value falling within the range is also specifically disclosed.

[0079] According to the present application, the term “substantially free” less than about 0.1 wt. % based on the total of the referenced value. According to the present application, the term “free” is 0.0 wt. % based on the total of the referenced value.

[0080] All ranges and values disclosed herein are inclusive and combinable. For examples, any value or point described herein that falls within a range described herein can serve as a minimum or maximum value to derive a sub-range, etc. Furthermore, all ranges provided are meant to include every specific range within, and combination of sub ranges between, the given ranges. Thus, a range from 1-5 includes specifically 1, 2, 3, 4 and 5, as well as sub ranges such as 2-5, 3- 5, 2-3, 2-4, 1-4, etc.

[0081] As used herein, the use of a compound comprising several isomers or stereoisomers includes all the isomeric forms of that compound. When referring to chemical structures, and names, the symbols “C”, “H”, and “O” mean carbon, hydrogen, and oxygen, respectively. The symbols “=” and “=” mean single bond, double bond, and triple bond, respectively. For readability purposes, the chemical functional groups are in their adjective form; for each of the adjective, the word “group” is assumed. For example, the adjective “alkyl” without a nouns thereafter, should be read as “an alkyl group.”

[0082] As used herein, the expression “at least one” is interchangeable with the expression “one or more” and thus includes individual components as well as mixtures / combinations.

[0083] The term “treat” (and its grammatical variations) as used herein refers to the application of compositions of the present disclosure onto the surface of skin and / or hair. The term ‘treat” (and its grammatical variations) as used herein also refers to contacting the skin or hair with the compositions of the present disclosure.

[0084] The term “active material” as used herein with respect to the percent amount of an ingredient or raw material, refers to 100% activity of the ingredient or raw material.

[0085] The term, “a mixture thereof’ or “a blend thereof” does not require that the mixture include all of A, B, C, D, E, and F (although all of A, B, C, D, E, and F may be included). Rather, it indicates that a mixture of any two or more of A, B, C, D, E, and F can be included. In other words, it is equivalent to the phrase “one or more elements selected from the group consisting of A, B, C, D, E, F, and a mixture of any two or more of A, B, C, D, E, and F.”

[0086] Likewise, the term “a salt thereof” also relates to “salts thereof.” Thus, where the disclosure refers to “an element selected from the group consisting of A, B, C, D, E, F, a saltthereof, and a mixture thereof,” it indicates that that one or more of A, B, C, D, and F may he included, one or more of a salt of A, a salt of B, a salt of C, a salt of D, a salt of E, and a salt of F may be included, or a mixture of any two of A, B, C, D, E, F, a salt of A, a salt of B, a salt of C, a salt of D, a salt of E, and a salt of F may be included.

[0087] The salts referred to throughout the disclosure may include salts having a counter-ion such as an alkali metal, alkaline earth metal, or ammonium counter-ion. This list of counter-ions, however, is non-limiting.

[0088] The phrase “stable emulsion” refers to a composition that does not undergo phase separation up to a temperature of 45 C° for at least two weeks.

[0089] The expression “inclusive” for a range of concentrations means that the limits of the range are included in the defined interv al.

[0090] The term “weight ratio” or “mass ratio” as used herein, references the amount of a substance in proportion to a mixture containing said substance, and is calculated by dividing the amount of said substance by weight contained in the mixture by the weight of the mixture containing said substance. As an example, a weight ratio of 0.4 for substance A in a mixture ofA, B, and C indicates that the weight of substance A divided by the total weight of substances A,B, and C is 0.4.

[0091] Some of the various categories of components identified may overlap. In such cases where overlap may exist and the composition includes both components (or the composition includes more than two components that overlap), an overlapping compound does not represent more than one component. For example, a fatty acid may be characterized as both a nonionic surfactant and a fatty compound. If a particular composition includes both a nonionic surfactant and a fatty compound, a single fatty acid will serve as only the nonionic surfactant or as only the fatty compound (the single fatty acid does not serve as both the nonionic surfactant and the fatty compound).

[0092] The term “Volatile”, as used herein, means having a flash point of less than about 100° C. The term “Non-volatile”, as used herein, means having a flash point of greater than about 100°C,

[0093] The term “polymers,” as defined herein, include homopolymers and copolymers formed from at least two different types of monomers.

[0094] All publications and patent applications cited in this specification are herein incorporated by reference, and for any and all purposes, as if each individual publication or patent application were specifically and individually indicated to be incorporated by reference. In the event of an inconsistency between the present disclosure and any publications or patent application incorporated herein by reference, the present disclosure controls.

[0095] Any member in a list of species that are used to exemplify or define a genus, may be mutually different from, or overlapping with, or a subset of, or equivalent to, or nearly the same as, or identical to, any other member of the list of species. Further, unless explicitly stated, such as when reciting a Markush group, the list of species that define or exemplify the genus is open, and it is given that other species may exist that define or exemplify the genus just as well as, or better than, any other species listed.

[0096] All components and elements positively set forth in this disclosure can be negatively excluded from the claims. In other words, the personal care compositions of the instant disclosure can be free or essentially free of all components and elements positively recited throughout the instant disclosure. In some instances, the personal care compositions of the present disclosure may be substantially free of non-incidental amounts of the ingredient(s) or compound(s) described herein. A non-incidental amount of an ingredient or compound is the amount of that ingredient or compound that is added into the personal care composition by itself. For example, a personal care composition may be substantially free of a non-incidental amount of an ingredient or compound, although such ingredient(s) or compound(s) may be present as part of a raw material that is included as a blend of two or more compounds.

[0097] Some of the various categories of components identified may overlap. In such cases where overlap may exist and the personal care composition includes both components (or the composition includes more than two components that overlap), an overlapping compound does not represent more than one component. For example, caprylyl glycol may be characterized as both a humectant and a preservative. If a particular personal care composition includes both a humectant and a preservative, caprylyl glycol will serve only as either a humectant or a preservative — not both.

[0098] As used herein, the terms “composition” and “formulation” can be used interchangeably within the specification.

[0099] Compositions disclosed herein may be or include an oral care product, an oral care composition, and / or a whitening composition thereof. In a non-limiting embodiment, the composition may be an oral care product or composition including a whitening composition, or the whitening composition thereof. In a non-limiting embodiment, the composition may be an oral care product including a whitening composition, a whitening composition and a separately contained pH booster, or a composition comprising both a whitening composition and a pH booster. In a non-limiting embodiment, the composition may be an oral care composition in the form of a gel.

[0100] The following discussion may be made in reference to a whitening composition - however, the discussion applies, generally, to the foregoing oral care product. The whitening composition of the present invention comprises an oxidizing agent. The whitening composition may further comprise at least one of a carrier and an adhesion agent. The whitening composition may further comprise at least one of a flavorant.

[0101] The whitening composition may comprise a carrier or an orally acceptable vehicle. In some embodiments, the oral care product or the whitening composition thereof may be anhydrous or non-aqueous prior to use. In a non-limiting example, the oral care product or the whitening composition thereof may be free of water, substantially free of water.

[0102] As used herein, “free of water” or “substantially free of water” may refer to a composition that contains water in an amount of less than 10 weight %, less than 8 weight %, less than 5 weight %, less than 3 weight %, less than 1 weight %, less than 0.1 weight %, less than 0.05 weight %, less than 0.01 weight %, less than 0.005 weight %, or less than 0.0001 weight %, based on a total weight of the oral care product or the whitening composition thereof.

[0103] In another implementation, the oral care product or the whitening composition thereof prior to use may have “low water content”. As used herein, “low water content” may refer to a composition that contains water in an amount greater than about 5 weight % or greater than about 10 weight %, and less than about 20 weight %, less than about 15 weight %, or less than about 10 weight %, based on a total weight of the oral care product or the whitening composition thereof.

[0104] The whitening composition may be substantially free of hydrogen peroxide. In a preferred embodiment, the whitening composition may be free of hydrogen peroxide - i.e.,contain 0.0 wt. % of hydrogen peroxide based on the total weight of the whitening composition. The oxidizing agent may contain 0.0 wt. % of hydrogen peroxide.

[0105] The phrase “free of hydrogen peroxide” may refer to both released hydrogen peroxide as well as components that are capable of releasing hydrogen peroxide when exposed to water. Such components that may include hydrogen peroxide or may be capable of releasing hydrogen peroxide include hydrogen peroxide, urea peroxide, calcium peroxide, a cross-linked polyvinylpyyrolidone (PVP) hydrogen peroxide complex, polyvinylpyrrolidone (PVP) hydrogen peroxide complex, sodium percarbonate, and combinations thereof.

[0106] The compositions disclosed herein may preferably be substantially free of or free of peroxides. In some embodiments, the composition disclosed herein may have about 1 wt.% or less, about 0.5 wt.% or less, about 0.3 wt.% or less, about 0.1 wt.% or less, about 0.05 wt.% or less, about 0.01 wt.% or less of peroxides, based on the total weight of the composition.

[0107] The oxidizing agent may comprise a salt of a peroxymonosulfate or a salt of monopersulfate (MPS). In some preferred embodiment, the oxidizing agent consists of a salt of a peroxymonosulfate or a salt of monopersulfate (MPS). The oxidizer may comprise an alkali metal salt of MPS, such as a potassium MPS, sodium MPS, ammonium MPS, or the like, or any combination thereof. In a preferred embodiment, the oxidizer may comprise potassium MPS (also referred to as potassium caroate). In some embodiments, the oxidizer may be potassium caroate.

[0108] MPS may be provided as a single molecule, a compound, such as a monopersulfate compound or MPS compound, a complex, such as a monopersulfate complex, or any combination thereof. In at least one implementation, the whitening composition may be or include an MPS compound or a mixture of two or more salts of peroxymonosulfate. The MPS compound may be or include a mixed salt or triple salt, such as (2KHSO5 KHSO4 K2SO4).In some embodiments, the oxidizer may comprise potassium caroate - wherein the potassium caroate is present in an amount of about 100 wt. % based on the total weight of the oxidizer.

[0109] The oxidizing agent may be present in an amount of greater than 0.0 wt. % up to about 15 wt. %, based on a total weight of the whitening composition - including all percentages and subranges there-between. In a non-limiting example, the oxidizing agent may be provided in an amount from greater than 0.0 weight %, about 0.5 weight %, about 1 weight %, about 1.5 weight %, about 2 weight %, about 2.5 weight %, about 3 weight %, about 3.5 weight %, about 4 weight%, or about 4.5 weight % to about 5 weight %, about 5.5 weight %, about 6 weight %, about 6.5 weight %, about 7 weight %, about 7.5 weight %, about 8 weight %, about 8.5 weight %, about 9 weight %, about 9.5 weight %, about 10 weight %, about 10.5 weight %, about 11 weight %, about 11.5 weight %, about 12 weight %, or any range or subrange formed therefrom, based on the total weight of the whitening composition.

[0110] In another example, the oxidizing agent may be provided in an amount from greater than 0.0 weight %, about 0.1 weight %, about 0.2 weight %, about 0.3 weight %, about 0.4 weight %, about 0.5 weight %, about 0.6 weight %, about 0.7 weight %, about 0.8 weight %, about 0.9 weight %, or about 1.0 weight % to about 1.1 weight %, about 1.2 weight %, about 1.3 weight %, about 1.4 weight %, about 1.5 weight %, about 1.6 weight %, about 1.7 weight %, about 1.8 weight %, about 1.9 weight %, about 2.0 weight %, about 2.1 weight %, about 2.2 weight %, about 2.3 weight %, about 2.4 weight %, about 2.5 weight %, about 2.6 weight %, about 2.7 weight %, about 2.8 weight %, about 2.9 weight %, about 3.0 weight %, about 3.1 weight %, about 3.2 weight %, about 3.3 weight %, about 3.4 weight %, about 3.5 weight %, or any range or subrange thereof, based on the total weight of the whitening composition.

[0111] In yet another example, the oxidizer agent may be provided in an amount from greater than 0.0 weight % to about 3.5 weight %, about 0.1 weight % to about 3.4 weight %, about 0.2 weight % to about 3.2 weight %, about 0.3 weight % to about 3.0 weight %, about 0.4 weight % to about 2.8 weight %, about 0.5 weight % to about 2.7 weight %, about 0.9 weight % to about 2.6 weight %, about 1.1 weight % to about 2.5 weight %, about 1.5 weight % to about 2.4 weight %, or about 1.8 weight % to about 2.3 weight % - based on the total weight of the whitening composition.

[0112] The whitening composition may comprise a carrier or an orally acceptable vehicle. With the orally acceptable vehicle or carrier, the resulting whitening composition may form one or more of a mouthwash, a toothpaste (dentifrice), a prophylactic paste, a tooth polish, a tooth gel (e.g., a whitening gel), a chewing gum, a lozenge, a whitening strip, a paint-on gel, varnish, veneer, a gel or paste coated on an application support such as dental floss or a toothbrush (e.g., a manual, electric, sound, a combination thereof or ultrasound toothbrush), or any combination thereof. In a typical implementation, the whitening composition may be a whitening gel or a gel whitening composition.

[0113] The orally acceptable vehicle may include one or more poloxamers. The poloxamers may be a liquid or a paste. The poloxamcr may have an average molecular weight of less than or equal to about 12,000 Dalton (Da), less than or equal to about 11,000 Da, less than or equal to about 10,000 Da, less than or equal to about 9,000 Da, less than or equal to about 8,000 Da, less than or equal to about 7,000 Da, or less than or equal to about 6,000 Da. Illustrative poloxamers may be or include, but are not limited to, one or more of (poly(ethylene glycol)-block- poly(propylene glycol)-block-poly(ethylene glycol)). In a preferred implementation, the orally acceptable vehicle includes a poly(ethylene glycol)-block-poly(propylene glycol)-block- poly(ethylene glycol) polymer.

[0114] The orally acceptable vehicle may include a thickening system having one or more thickeners. The one or more thickeners may be any orally acceptable thickener or thickening agent configured to control the viscosity of the oral care product or the whitening composition thereof. Illustrative thickeners may be or include, but are not limited to, colloidal silica, fumed silica, polyvinylpyrrolidone (PVP), a cross-linked polyvinylpyrrolidone (PVP) polymer, crosslinked polyvinylpyrrolidone (PVP), or the like, or mixtures or combinations thereof.

[0115] In some embodiments, the thickening system includes a polyvinylpyrrolidone (PVP), cross-linked polyvinylpyrrolidone (PVP) polymer, or combinations thereof. Thickeners may also be or include, but are not limited to, carbomers (e.g., carboxyvinyl polymers), carrageenans - such as, but not limited to - Irish moss, carrageenan, iota-carrageenan - high molecular’ weight polyethylene glycols, cellulosic polymers, hydroxyethylcellulose, carboxymethylcellulose, and salts thereof (e.g., CMC sodium), natural gums (e.g., karaya gum, xanthan gum, gum arabic, and tragacanth gum), colloidal magnesium aluminum silicate, or the like, or mixtures or combinations thereof.

[0116] The whitening composition may comprise PVP in an amount ranging from about 1 wt. % to about 30 wt. %, based on the total weight of the whitening composition - including all percentages and sub-ranges there-bet ween. In some embodiments, the whitening composition may comprise PVP in an amount ranging from about 2.0 wt. % to about 22 wt. %, based on the total weight of the whitening composition - including all percentages and sub-ranges therebetween. In some embodiments, the whitening composition may comprise PVP in an amount of about 3.0 wt. %, based on the total weight of the whitening composition. In some embodiments, the whitening composition may comprise PVP in an amount of about 5.0 wt. %, based on thetotal weight of the whitening composition. In some embodiments, the whitening composition may comprise PVP in an amount of about 20.7 wt. %, based on the total weight of the whitening composition.

[0117] The whitening composition may comprise fumed silica in an amount ranging from about 0.1 wt. % to about 5 wt. %, based on the total weight of the whitening composition - including all percentages and sub-ranges there-between. In some embodiments, the whitening composition may comprise fumed silica in an amount ranging from about 1.0 wt. % to about 4 wt. %, based on the total weight of the whitening composition - including all percentages and sub-ranges there-between. In some embodiments, the whitening composition may comprise fumed silica in an amount of about 2.5 wt. %, based on the total weight of the whitening composition. In some embodiments, the whitening composition may comprise fumed silica in an amount of about 1.0 wt. %, based on the total weight of the whitening composition. In some embodiments, the whitening composition may comprise fumed silica in an amount of about 4.0 wt. %, based on the total weight of the whitening composition. In some embodiments, the whitening composition may comprise fumed silica in an amount of about 2.5 wt. %, based on the total weight of the whitening composition.

[0118] In a more typical implementation, the thickening system may include an organic polymer, which may also be configured as an adhesion enhancing agent. Illustrative organic polymers may be or include, but are not limited to, hydrophilic polymers, such as carbomers, such as carboxymethylene polymers, such as acrylic acid polymers, and acrylic acid copolymers, carboxypolymethylene is a slightly acidic vinyl polymer with active carboxyl groups. In a typical embodiment, the thickening system includes a carboxypolymethylene.

[0119] The amount or concentration of the thickening system and / or any one or more of the thickeners thereof present in the oral care product or the whitening composition thereof may vary widely. The amount of the thickening system and / or the thickeners thereof present in the whitening composition thereof may be from about 1 weight % to about 99 weight %, based on the total weight of the oral care product or the whitening composition thereof.

[0120] In a non-limiting example, the amount of the thickening system and / or the thickeners thereof present may be from about 1 weight %, about 2 weight %, about 3 weight %, about 4 weight %, about 5 weight %, about 6 weight %, about 7 weight %, about 8 weight %, about 9 weight %, about 10 weigh %, about 15 weight %, about 20 weight %, or about 21 weight % toabout 22 weight %, about 23 weight %, about 24 weight %, about 25 weight %, about 26 weight %, about 27 weight %, about 28 weight %, about 29 weight %, about 30 weight %, or more, based on a total weight of the oral care product or the whitening composition thereof. In another example, the amount of the thickening system and / or the thickeners thereof present may be from about 1 weight % to about 30 weight %, about 3 weight % to about 29 weight %, about 14 weight % to about 28 weight %, about 15 weight % to about 27 weight %, about 16 weight % to about 26 weight %, about 17 weight % to about 25 weight %, about 18 weight % to about 24 weight %, about 19 weight % to about 23 weight %, or about 20 weight % to about 22 weight %. In a typical implementation, the amount of the thickening system and / or the thickeners thereof present in the oral care product or the whitening composition thereof may be from about 10 weight % to about 20 weight % or about 1.2 weight % to about 1.8 weight %.

[0121] In at least one embodiment, the total amount of thickeners present in the compositions disclosed herein is about 0.5 to about 7 wt.%, based on the total weight of the compositions disclosed herein. For example, the total amount of total amount of thickeners in the compositions disclosed herein may be about 0.5 to about 7 wt.%, about 0.5 to about 6 wt.%, about 0.5 to about 5 wt.%, about 0.5 to about 4 wt.%, about 0.5 to about 3 wt.%, about 0.5 to about 2 wt.%; from about 1 to about 7 wt.%, about 1 to about 6 wt.%, about 1 to about 5 wt.%, about 1 to about 4 wt.%, about 1 to about 3 wt.%, about 1 to about 2 wt.%; about 1.5 to about 7 wt.%, about 1.5 to about 6 wt.%, about 1.5 to about 5 wt.%, about 1.5 to about 4 wt.%, about 1.5 to about 3 wt.%; about 2 to about 7 wt.%, about 2 to about 6 wt.%, about 2 to about 5 wt.%, about 2 to about 4 wt.%, about 0.5 to about 3 wt.%, about 0.5 to about 2 wt.%; about 3 to about 7 wt.%, about 3 to about 6 wt.%, about 3 to about 5 wt.%, or any range or subrange thereof, based on the total weight of the composition (e.g., whitening composition).

[0122] The orally acceptable vehicle may include one or more thickener that is a structurebuilding agents. The structure-building agent may be capable of or configured to form a gel or a gel structure via self-assembly. The structure-building agent may be capable of or configured to form a gel with the other structure-building agents and / or the one or more components of the orally acceptable vehicle by interacting with the other structure-building agents and / or the one or more components of the orally acceptable vehicle via any one or more intermolecular forces (e.g., van der Waal, dipole-dipole, hydrogen bonding, covalent bonding, etc.).

[0123] In some implementations, the structure-building agent may be or include a polymer. In some examples, the structure-building agent may be or include an amphiphilic copolymer, where the amphiphilic copolymer is composed of two or more monomers, where at least one of the monomers is hydrophilic (e.g., vinylpyrrolidone), and where at least one of the monomers is hydrophobic (e.g., vinyl acetate). It should be appreciated that an amphiphilic copolymer may be capable of or configured to interact with both hydrophilic and hydrophobic components, substances, and liquids. In at least one implementation, the structure-building agent may be or include, but is not limited to, a poloxamer, as described above, a cross-linked polymer, such as cross-linked polyvinylpyrrolidone (“PVP”), a polyvinylpyrrolidone copolymer, a polyvinylpyrrolidone vinyl acetate copolymer, or any combination thereof.

[0124] Illustrative structure-building agent agents may be or include, but are not limited to, N- vinyl lactam based polymers and copolymers. The monomers for preparing a vinyl lactam-based polymer or co-polymer of the present application includes any monomer having 3 to 8 atoms in a heterocyclic ring, comprising a carbonyl carbon atom and a heteroatom (such as N, S, O) in its vinyl moiety. Suitable monomers include but not limited to N-vinyl-2-pyrrolidone, N-vinyl-2- piperidone, N-vinyl-3-methyl-pyrrolidinone, N-vinyl-3-methyl-piperidone, N-vinyl-3-methyl- caprolactam, N-vinyl-4-methyl-pyrrolidinone, N-vinyl-4-methyl-2-pyrrolidone, N-vinyl-4- methyl-piperidone, N-vinyl-4-methyl-caprolactam, N-vinyl-5-methyl-pyrrolidinone, N-vinyl-5- ethyl-2-pyrrolidone, N-vinyl-4-methyl-piperidone, N-vinyl-3-ethyl-pyrrolidinone, N-vinyl-4,5- dimethyl-pyrrolidinone, N-vinyl-5,5-dimethyl-pyrrolidinone, N-vinyl-3,3,5-trimethyl- pyrrolidinone, N-vinyl-5-methyl-5-ethyl-pyrrolidinone, N-vinyl-3,4,5-trimethyl-3-ethyl- pyrrolidinone, N-vinyl-6-methyl-2-piperidone, N-vinyl-6-ethyl-2-piperidone, N-vinyl-3,5- dimethyl-2-piperidone, N-vinyl-4,4-dimethyl-2-piperidone, N-vinyl-2-caprolactam, N-vinyl-7- methyl-caprolactam, N-vinyl-7-ethyl-caprolactam, N-vinyl-3,5-dimethyl-caprolactam, N-vinyl- 4,6-dimethyl-caprolactam, N-vinyl-3,5,7-trimethyl-caprolactam, N-vinyl-2-valerolactam, N- vinyl-hexahydro-2-azepinone, N-vinyl-octahydro-2-azocinone, N-vinyl octahydro-2-azoninone, N-vinyl decahydro-2-azecinone, or the like, or combinations thereof.

[0125] The amount or concentration of any one or more of the structure-building agents present in the oral care product or the whitening composition thereof may vary widely. The amount of any one or more of the structure-building agents present in the oral care product or the whiteningcomposition thereof may be from about 1 weight % to about 99 weight %, based on the total weight of the oral care product or the whitening composition thereof.

[0126] In a non-limiting example, the amount of the thickening system and / or the thickeners thereof present may be from about 1 weight %, about 2 weight %, about 3 weight %, about 4 weight %, about 5 weight %, about 6 weight %, about 7 weight %, about 8 weight %, about 9 weight %, about 10 weigh %, about 15 weight %, about 20 weight %, or about 21 weight % to about 22 weight %, about 23 weight %, about 24 weight %, about 25 weight %, about 26 weight %, about 27 weight %, about 28 weight %, about 29 weight %, about 30 weight %, or more, based on a total weight of the oral care product or the whitening composition thereof. In another example, the amount of any one or more of the structure-building agents present may be from about 1 weight % to about 99 weight %, about 3 weight % to about 90 weight %, about 14 weight % to about 80 weight %, about 15 weight % to about 80 weight %, about 16 weight % to about 70 weight %, about 17 weight % to about 60 weight %, about 18 weight % to about 50 weight %, about 19 weight % to about 40 weight %, or about 20 weight % to about 30 weight %. In a typical implementation, the amount of any one or more of the structure-building agents present in the oral care product or the whitening composition thereof may be from about 10 weight % to about 20 weight %, more typically about 1.2 weight % to about 1.8 weight %, and more typically about 1.5 weight %.

[0127] In some implementations, the oral care product or the orally acceptable vehicle thereof may include a hydrophobic component. The hydrophobic component may be or include a hydrophobic polymer, such as a silicone polymer. The term “hydrophobic” or “water-insoluble” as applied to polymers and as employed herein may refers to an organic polymer that is substantially non-aqueous and having a water solubility of less than one gram per 100 grams of water at 25° C.

[0128] In some implementations, the hydrophobic polymers suitable for use in the present invention may be referred to as siloxane polymers, white petrolatum, or combinations thereof. The siloxane polymer may generally refer to “silicone” polymers. In certain implementations, the hydrophobic polymers may include those in which a whitening agent may be dispersed. In a preferred implementation, the hydrophobic polymers may be or include, but are not limited to, silicone-based hydrophobic polymer, such as polyorganosiloxane, in particular polydimethylsiloxane.

[0129] In some implementations, the siloxane polymers that may function as part of the hydrophobic component arc in the form of a fluid. Polysiloxanc fluids (also referred to as silicone fluid) useful herein for the hydrophobic silicone material component include those with a viscosity, as measured at 25° C., of about 1 centipoise (cP) to about 1000 cP, or about 2 cP to about 500 cP, or about 20 cP to about 400 cP.

[0130] Polysiloxane fluids for use herein may be linear or cyclic, and may be substituted with a wide variety of substituents. The substituents may be or include, but are not limited to, methyl, ethyl, phenyl substituents, or the like, or mixtures thereof. Suitable polysiloxane fluids may include linear polysiloxane polymers such as dimethicone and other low viscosity analogues of the polysiloxane materials, having a viscosity of about 200 cP or less and cyclomethicone, and other cyclic siloxanes having a viscosity of about 200 cP or less. Other fluids include polysiloxane polyether copolymers and hydroxy terminated polydimethyl-siloxane fluid. High molecular silicone resins with a poly siloxane blend may also be used including powdered trimethylsiloxysilicate.

[0131] In some implementations, the hydrophobic component may be or include a silicone fluid, white petrolatum, or combinations thereof. In some implementations, the silicone fluid may be or include a siloxane polymer.

[0132] The compositions disclosed herein may include one or more silicone fluid in an amount of about 15 to about 70 wt.%, based on the total weight of the composition. For example, a whitening composition may comprise the one of more silicone fluid in an amount from about 40 to about 65 wt.%, about 40 to about 60 wt.%, about 40 to about 55 wt.%, about 40 to about 50 wt.%; from about 45 to about 65 wt.%, about 45 to about 60 wt.%, about 45 to about 55 wt.%, about 45 to about 50 wt.%; from about 50 to about 65 wt.%, about 50 to about 60 wt.%, or any range or subrange thereof, based on the total weight of the whitening composition (e.g., without a pH booster). In other cases, the composition may comprise the whitening composition and a pH booster and have a total amount of silicone fluid of about 15 to about 40 wt.%, about 15 to about 35 wt.%, about 15 to about 30 wt.%, about 15 to about 25 wt.%; from about 20 to about 40 wt.%, about 20 to about 35 wt.%, about 20 to about 30 wt.%; from about 25 to about 40 wt.%, about 25 to about 35 wt.%, about 25 to about 30 wt.%, or any range or subrange thereof, based on the total weight of the composition containing a mixture and / or combination of the whitening composition and the pH booster composition.

[0133] The hydrophobic component may be present in the oral care product or the whitening composition thereof in an amount of from about 10 weight % to about 95 weight %, about 10 weight % to about 80 weight %, about 10 weight % to about 60 weight %, about 10 weight % to about 40 weight %, about 10 weight % to about 30 weight %, based on a total weight of the oral care product or the whitening composition thereof.

[0134] The whitening composition may comprise one or more of an adhesive or adhesion enhancing agent. In some embodiments, the whitening composition thereof may optionally include one or more adhesives configured to improve, maintain, and / or facilitate the adhesion of the oral care product or the whitening composition thereof to surfaces of the oral cavity. The one or more adhesives may also be configured to increase the hydrophobicity of a film formed from the oral care product or the whitening composition thereof, thereby allowing the film to withstand external challenges, such as abrading, rubbing, or brushing.

[0135] Illustrative adhesives may be or include, but are not limited to, alkyd resins, polyvinyl acetaldehydes, polyvinyl alcohols, polyvinyl acetates, poly(ethylene oxide), polyacrylates, ketone resins, polyvinylpyrolidone, polyvinylpyrolidone / vinyl acetate copolymer, polyethylene glycols of 200 to 1000 molecular weight, polyoxyethylene / polyoxopropylene block copolymers (Polyox), silicon resins, or the like, and mixtures or combinations thereof. In at least one implementation, the one or more adhesives may include siloxane polymers, which are also generally known in the art as “silicone” polymers. Illustrative silicone-based hydrophobic polymers may be or include, but are not limited to, polyorganosiloxane, polydiorganosiloxane, and the like, and combinations thereof. In at least one implementation, the adhesion enhancing agent includes at least one silicon pressure sensitive adhesive (PSA). Such PSAs may be pressure sensitive hydrophobic polymers specifically designed for pharmaceutical use and are permeable to many drug compounds and find application for the transdermal application of various compounds. In some implementations, the silicone polymers are the copolymer product of mixing a silanol terminated polydiorganosiloxane, such as polydimethyl siloxane, with a silanol- containing silicone resin, whereby the silanol groups of the polydiorganosiloxane undergo a condensation reaction with the silanol groups of the silicone resin such that the polydiorganosiloxane is lightly crosslinked by the silicone resin (that is, the polydiorganosiloxane chains are bonded together through the resin molecules to give chainbranching and entanglement and / or a small amount of network character) to form the silicone hydrophobic polymers.

[0136] The modification of a ratio of silicone resin to polydiorganosiloxane modifies the tackiness of the polymer. The ratio of the silicone resin to polydiorganosiloxane may be in the range of about 70:30 to about 50:50 - including all ratios and sub-ranges there-between. Nonlimiting examples of the ratio of silicone resin to polydiorganosiloxane include 65:35 (low tack), 60:40 (medium tack), and 55:45 (high tack). Such a polyorganosiloxane PSA is available dissolved in either ethyl acetate solvent or dimethicone.

[0137] The one or more adhesives or adhesion enhancing agents may be present in the oral care product or the whitening composition thereof in an amount of from about 10 weight % to about 80 weight %, about 10 weight % to about 60 weight %, about 10 weight % to about 50 weight %, about 10 weight % to about 40 weight %, about 10 weight % to about 30 weight %, based on a total weight of the oral care product or the whitening composition thereof.

[0138] The whitening composition may, preferably, be substantially free of or free of water. In some embodiments, the whitening composition may have about 3 wt.% or less, about 2 wt.% or less, about 1 wt.% or less, about 0.5 wt.% or less, about 0.1 wt.% or less, based on the total weight of the whitening composition.

[0139] The whitening composition may comprise one or more flavoring agents. Illustrative flavoring agents may include, but are not limited to, essential oils and various flavoring aldehydes, esters, alcohols, or the like. The flavoring agents may also include, but are not limited to, sweeteners, sucralose, dextrose, polydextrose, sucrose, maltose, dextrin, dried invert sugar, mannose, xylose, ribose, fructose, levulose, galactose, com syrup (including high fructose com syrup and com syrup solids), partially hydrolyzed starch, hydrogenated starch hydrolysate, sorbitol, mannitol, xylitol, maltitol, isomalt, aspartame, neotame, saccharin and salts thereof (e.g., sodium saccharin), dipeptide-based intense sweeteners, cyclamates, dihydrochalcones, or the like, or mixtures thereof.

[0140] Examples of the essential oils include oils of spearmint, peppermint, wintergreen, sassafras, clove, sage, eucalyptus, marjoram, cinnamon, lemon, lime, grapefruit, and orange. In another example, the flavoring agents may include menthol, carvone, and anethole. In a preferred implementation, the flavoring agent includes peppermint and spearmint. In a more preferred implementation, the flavoring agent includes a Firmenich Newman Flavor.

[0141] The amount of any one or more of the flavoring agent in the oral care product or the whitening composition thereof may be less than 1.0 weight %, less than 0.9 weight %, less than 0.8 weight %, or less than 0.7 weight %. For example, the amount of the flavoring agent in the oral care product or the whitening composition thereof may be about 0.0 weight % to about 1.0 weight %, about 0.5 weight % to about 0.9 weight %, about 0.7 weight % to about 0.8 weight %. In a preferred implementation, the amount of the flavoring agent in the oral care product or the whitening composition thereof is about 0.01 weight % to about 0.4 weight %, preferably about 0.1 weight % to about 0.3 weight %, or about 0.2 weight %.

[0142] The whitening composition may comprise one or more additional ingredients. It should be appreciated to one having ordinary skill in the art, that the oral care products and / or the whitening composition thereof may include other additional ingredients / components. For example, the oral care products and / or the whitening composition thereof may include anti-caries agents, desensitizing agents, viscosity modifiers, diluents, mouth feel agents, colorants, preservatives, or the like, or combinations or mixtures thereof. It should further be appreciated by one having ordinary skill in the art that while general attributes of each of the above categories of materials may differ, there may be some common attributes and any given material may serve multiple purposes within two or more of such categories of materials.

[0143] In at least one implementation, the additional ingredients / components may include one or more active materials configured to prevent and / or treat one or more conditions and / or disorders of the oral cavity. For example, the one or more active materials may be configured to prevent and / or treat one or more conditions and / or disorders of hard and / or soft tissue of the oral cavity. The active materials may also be configured to prevent and / or treat one or more physiological disorders and / or conditions, and / or provide a cosmetic benefit to the oral cavity.

[0144] In at least one implementation, the oral care products and / or the whitening composition thereof may include an anticalculus agent. Generally, anticalculus agents may not be compatible with some whitening compositions, however, implementations of the present disclosure may incorporate anticalculus agents and the whitening composition into a single phase oral care product. Illustrative anticalculus agents may include, but are not limited to, phosphates and polyphosphates (e.g., pyrophosphates), polyaminopropanesulfonic acid (AMPS), hexametaphosphate salts, zinc citrate trihydrate, polypeptides, polyolefin sulfonates, polyolefin phosphates, diphosphonates. In a typical implementation, the anticalculus agents includescalcium pyrophosphate, tetrasodium pyrophosphate (TSPP), sodium tripolyphosphate (STPP), or a combination thereof.

[0145] The oral care products and / or the whitening composition thereof may optionally include one or more antimicrobial agents and / or one or more preservatives such as, methylisothiazolinone (MIT), sodium benzoate, potassium sorbate, benzyl alcohol, or the like, or combinations thereof. In another example, the oral care composition may include one or more antibacterial agents selected from halogenated diphenyl ether (e.g. triclosan), herbal extracts and essential oils (e.g., rosemary extract, tea extract, magnolia extract, thymol, menthol, eucalyptol, geraniol, carvacrol, citral, hinokitol, catechol, methyl salicylate, epigallocatechin gallate, epigallocatechin, gallic acid, miswak extract, sea-buckthorn extract), bisguanide antiseptics (e.g., chlorhexidine, alexidine or octenidine), quaternary ammonium compounds (e.g., cetylpyridinium chloride (CPC), benzalkonium chloride, tetradecylpyridinium chloride (TPC), N-tetradecyl-4- ethylpyridinium chloride (TDEPC)), phenolic antiseptics, hexetidine, octenidine, sanguinarine, povidone iodine, delmopinol, salifluor, other metal ions (e.g., stannous salts, copper salts, iron salts), sanguinarine, propolis and oxygenating agents (e.g., hydrogen peroxide, buffered sodium peroxyborate or peroxycarbonate), phthalic acid and its salts, monoperthalic acid and its salts and esters, ascorbyl stearate, oleoyl sarcosine, alkyl sulfate, dioctyl sulfosuccinate, salicylanilide, domiphen bromide, delmopinol, octapinol, and other piperidino derivatives, nicin preparations, chlorite salts; or mixtures of any of the foregoing. In a typical implementation, the antibacterial agent includes cetylpyridinium chloride (CPC). For example, all of the dual-phase mouthwash compositions disclosed herein may include CPC as an antibacterial agent.

[0146] The oral care products and / or the whitening composition thereof may include an antioxidant. Any orally acceptable antioxidant may be used, including, but not limited to, butylated hydroxyanisole (BHA), butylated hydroxytoluene (BHT), vitamin A, carotenoids, vitamin E, flavonoids, polyphenols, ascorbic acid, herbal antioxidants, chlorophyll, melatonin, or the like, or combinations or mixtures thereof.

[0147] The amount or concentration of any one or more of the additional ingredients / components present in the oral care product or the whitening composition thereof may vary widely. The amount of any one or more of any one or more of the additional ingredients / components present in the oral care product or the whitening composition thereofmay be from about 1 weight % to about 99 weight %, based on the total weight of the oral care product or the whitening composition thereof.

[0148] In a non-limiting example, the amount of any one or more of the additional ingredients / components present may be from about 1 weight %, about 2 weight %, about 3 weight %, about 4 weight %, about 5 weight %, about 6 weight %, about 7 weight %, about 8 weight %, about 9 weight %, about 10 weigh %, about 15 weight %, about 20 weight %, or about 21 weight % to about 22 weight %, about 23 weight %, about 24 weight %, about 25 weight %, about 26 weight %, about 27 weight %, about 28 weight %, about 29 weight %, about 30 weight %, or more, based on a total weight of the oral care product or the whitening composition thereof. In another example, the amount of any one or more of the additional ingredients / components present may be from about 1 weight % to about 99 weight %, about 3 weight % to about 90 weight %, about 14 weight % to about 80 weight %, about 15 weight % to about 80 weight %, about 16 weight % to about 70 weight %, about 17 weight % to about 60 weight %, about 18 weight % to about 50 weight %, about 19 weight % to about 40 weight %, or about 20 weight % to about 30 weight %. In a typical implementation, the amount of any one or more of the additional ingredients / components present in the oral care product or the whitening composition thereof may be from about 10 weight % to about 20 weight %, more typically about 1.2 weight % to about 1.8 weight %, and more typically about 1.5 weight %.

[0149] The whitening composition of the present invention may exhibit a pH ranging from about 6 to 8 - including all pH values and sub-ranges there-between. For instance, the whitening composition may preferably have a pH of about 6.5 to 8, about 7 to 8; from about 6 to about 7.5, about 6.5 to about 7.5, about 6 to about 7, or any range or subrange thereof.

[0150] The present invention further provides a two-part whitening composition comprising a first whitening component and a second whitening component, which typically is a pH boosting composition / formulation. The first whitening component may be the whitening composition previously discussed. The two-part whitening composition may comprise a first whitening component a second whitening component that is contained separately from the first whitening component. In some embodiments, the two-part whitening composition comprise a first whitening component and a second whitening component, wherein the first whitening component arc contained in the same container. For example, the first whitening component and the second whitening component may be homogeneously mixed together, may be in the form oftwo phases having a single phase interface between the two phases, and / or may be in the form of an emulsion. Preferably, the two-part whitening composition consists of the first whitening component and the second whitening component.

[0151] The second whitening component may comprise an alkali component and / or alkali earth metal component.

[0152] The first whitening component to the second whitening component may be present in a weight ratio ranging from about 1.0:2.0 to about 2.0: 1.0 - including all ratios and sub-ranges there-between. For example, in some embodiments, provided is a composition comprising the first whitening component and the second whitening component in a weight ratio of the first whitening component to the second whitening component of about 1 to about, about 1.3 to about 2, about 1.5 to about 2, about 1 to about 1.7, or about 1 to about 1.5. In some embodiments, the weight ratio of the first whitening component to the second whitening may be about 1:1.

[0153] The alkali component may comprise one or more of sodium bicarbonate and sodium carbonate. Additional examples of the alkali component include potassium carbonate, potassium bicarbonate, calcium carbonate, and / or calcium bicarbonate. The alkali component may comprise sodium bicarbonate and sodium carbonate in a weight ratio ranging from about 6:1 to about 12:1 - narrowing to about 8:1 to about 9:1. The alkali component may be present in the second whitening component in an amount from about 1 to about 5 wt.%, about 2 to about 5 wt.%, about 3 to about 5 wt.%; from about 1 to about 4 wt.%, about 2 to about 4 wt.%, about 3 to about 4 wt.%; from about 1 to about 3 wt.%, about 2 to about 3 wt.%, or any range or subrange thereof, based on the total weight of the second whitening component.

[0154] Preferably, the second whitening component is free of bases other than sodium carbonate, sodium bicarbonate, potassium carbonate, potassium bicarbonate, calcium carbonate, and calcium bicarbonate. Additionally, the first whitening component is preferably free of bases other than sodium carbonate, sodium bicarbonate, potassium carbonate, potassium bicarbonate, calcium carbonate, and calcium bicarbonate. In some preferred embodiments, the two two-part composition (e.g., both the first whitening component and the second whitening component) are free of sodium carbonate, sodium bicarbonate, potassium carbonate, potassium bicarbonate, calcium carbonate, and calcium bicarbonate.

[0155] The second whitening component may have a pH ranging from 8 to about 11 - including all pH values and sub-ranges there-between. For example, the second whitening component maypreferably have a pH of 8.5 to about 11 , about 9 to about 1 1 , about 10 to about 1 1 ; from 8.5 to about 10, about 9 to about 10, or any range or subrange thereof.

[0156] The second whitening component may further comprise a liquid carrier and a thickener. The liquid carrier may be aqueous. The liquid carrier may comprise one or more of glycerin, water, and combinations thereof. The liquid carrier may comprise water. The water may present in the second whitening component in an amount of about 50 to about 80 wt.%, based on the total weight of the second whitening component. For example, the total amount of water in the second whitening component may be from about 50 to about 70 wt.%, about 50 to about 65 wt.%, about 50 to about 60 wt.%; from about 55 to about 70 wt.%, about 55 to about 65 wt.%, about 60 to about 70 wt.%, or any range or subrange thereof, based on the total weight of the second whitening component.

[0157] The thickener of the second whitening component may comprise or consist of any of the thickeners described above with regard to the whiting composition (e.g., the first whitening composition). The thickener of the second whitening component may comprise carboxymethylcellulose sodium.

[0158] The liquid carrier may be present in an amount ranging from about 10 wt. % to about 99 wt. % based on the total weight of the second whitening component. The water may be present in an amount ranging from about 30 wt. % to about 90 wt. % based on the total weight of the second whitening component. The glycerin may be present in an amount ranging from about 10 wt. % to about 50 wt. % based on the total weight of the second whitening component.

[0159] The thickener may be present in an amount ranging from about 1 wt. % to about 8 wt. % based on the total weight of the second whitening component.

[0160] After combining the first whitening component and the second whitening component - the resulting blend may exhibit a pH ranging from 8 to about 11 - including all pH values and sub-ranges there-between. For example, the composition obtained by combining the first whitening component and the second whitening component may preferably have a pH of 8.5 to about 11, about 9 to about 11, about 10 to about 11; from 8.5 to about 10, about 9 to about 10, or any range or subrange thereof.

[0161] All ingredients for use in the compositions described herein should be orally acceptable. By “orally acceptable” as the term is used herein is meant an ingredient that is present in acomposition as described in an amount and form that does not render the composition unsafe for use in the oral cavity.

[0162] The present disclosure also provides methods for whitening teeth in a human or with the oral care product and / or the whitening composition disclosed herein. The method may include contacting the oral care product, the whitening composition, or the source of hydrogen peroxide thereof with water to initiate the formation of hydrogen peroxide. The method may also include contacting the oral care product or the whitening composition thereof with surfaces of the oral cavity, such as surfaces of teeth.

[0163] In some implementations, contacting the surface of the teeth with the oral care product or the whitening composition thereof may include directly applying the oral care product or the whitening composition to the teeth using a delivery device, such as a pen, a liquid stick having an applicator, such as a felt tip, brush, roller ball, non-woven pad, or the like. In another implementation, contacting the surface of the teeth with the oral care product or the whitening composition thereof may include disposing the oral care product or the whitening composition thereof in a dental tray (e.g., reservoir of the dental tray) and disposing the dental tray about the teeth.

[0164] The oral care product or the whitening composition may be applied to the teeth and left for at least 2 minutes, at least 5 minutes, typically at least 10 minutes, or more typically at least 30 minutes. After each treatment with the whitening composition the teeth may be treated with a tooth desensitizing formulation. Illustrative desensitizing formulations may contain potassium nitrate, citric acid, citric acid salts, strontium chloride or the like.

[0165] The oral care product and / or the whitening composition thereof may be applied and / or contacted with the surfaces of the teeth at predetermined intervals. For example, a daily basis, at least once a day for multiple days, or alternatively every other day. In another example, the oral care product and / or the whitening composition thereof may be applied and / or contacted with the surfaces of the teeth at least once a day, at least once every two days, at least once every three days, at least once every five days, at least once a week, at least once every two weeks, or at least once a month. The oral care product and / or the whitening composition thereof may be utilized for up to 2 weeks, up to 3 weeks, up to 4 weeks, up to 6 weeks, up to 8 weeks, or greater.

[0166] The dental tray may be of any conventional form, and may be formed from conventionally used polymers, such as thermoplastic polymers. Thermoset polymers also may beused. Accordingly, the dental tray may range from highly flexible to a low flexibility. The thermoplastic polymers arc typically used. Illustrative thermoplastic polymers may be or include, but are not limited to, polyethylene and polypropylene polymers, their derivatives and copolymers, silicone elastomers, polyurethanes and derivatives, polycaprolactams, polystyrene and derivatives, polybutadiene and derivatives, polyisoprene and derivatives, and polymethacrylate and its derivatives, or the like, or combinations thereof.

[0167] All ingredients for use in the compositions described herein should be orally acceptable. As used herein, “orally acceptable” may refer to any ingredient that is present in a composition as described in an amount and form that does not render the composition unsafe for use in the oral cavity.

[0168] The present further provides a method of manufacturing a personal care product having viscosity control. The method comprising: blending together the viscosity control composition with personal care ingredients to form the personal care composition. Subsequently, the method comprises adding a predetermined volume of the personal care composition to the container to form the personal care product.EXAMPLES

[0169] The following experiments tested the impact on stability using the emulsifier / dispersant in combination with the UV filter and emollient of the present invention. The examples used the following formulation details.

[0170] Oxidizer: potassium caroate

[0171] Carrier 1: Trimethylsiloxysilicate / Dimethiconol Crosspolymer and Dimethicone

[0172] Carrier 2: white petrolatum

[0173] Carrier 3: Polyethylene glycol 600, Poloxamer 105, and PEG / PPG-116 / 66 Copolymer

[0174] PVP: polyvinyl pyrrolidone

[0175] Flavorant 1: one or more of sodium saccharin and sucralose

[0176] Flavorant 2: one or more mint flavor oilsExample 1

[0177] A first experiment was performed to determine the whitening efficacy of the whitening composition of the present invention. Four non-limiting example whitening compositions (Exs. 1-4) were prepared in accordance with aspects of the disclosure. A comparative composition(Comp. Ex. 1 ) was also prepared as a comparison to Example Compositions 1-4. The formulations for Example Compositions 1-4 and Comparative Composition 1 arc shown in Table 1. Each formulation was prepared by blending the ingredients together and applying the respective oral care composition to stained tooth surfaces for equal periods of time for a number of equal treatments. The teeth were stained with coffee and tea. Subsequently, after the treatment cycles were completed, each tooth color value (L*a*b) were measured and recorded and compared against color values from the initial recording made of each tooth before treatments started. Whiteness is reported as AW*.W* = (a*2 + b*2 + (L* - 100)2)1 / 2AW* = W* treated - W* baseline

[0178] Regarding AW, the more negative the value the closer the tooth is closer to white color. The results are set forth below in Table 1.Table 1

[0179] As demonstrated by Table 1, the addition of the MPS provides an effective tooth whitening composition - as evidenced by the color change values showing at least a AW* of -7.8 (Ex. 3) going up to a AW* over -10 (Ex. 1). Furthermore, each of the formulations were determined to be stable by exhibiting storage stability issues over a period of time indicative of shelf-stable life span needed for commercial whitening products.Example 2

[0180] A second experiment was performed to determine the whitening efficacy of the pH boosting agent used in combination with the whitening composition of the present invention. A pH boosting formulation was prepared as set forth in Table 2.Table 2

[0181] Subsequently, two non-limiting example compositions (Ex. 5 and Ex. 6) as well as a placebo were prepared and subjected to similar tooth whitening tests as Experiment 1, however, on bovine teeth artificially stained with tobacco - whereby the formulation of Ex. 6 was combined with the pH booting formulation in a 1:1 weight ratio while the formulation of Ex. 5 was not combined with the pH boosting agent. The results are set forth below in Table 3.Table 3

[0182] As demonstrated by Table 4, it has been surprisingly discovered that the addition of the pH boosting agent in combination with the MPS oxidizer creates a substantial improvement in whitening effect - even in the absence of Flavorant 2.

[0183] While the invention has been described with respect to specific examples including presently preferred modes of carrying out the invention, those skilled in the art will appreciate that there are numerous variations and permutations of the above described systems and techniques. It is to be understood that other embodiments may be utilized and structural and functional modifications may be made without departing from the scope of the present invention. Thus, the spirit and scope of the invention should be construed broadly as set forth in the appended claims.

Claims

CLAIMSWhat is claimed is:

1. A whitening composition comprising: an oxidizing agent comprising potassium caroate; a carrier comprising a polymeric fluid; an adhesion agent; and a flavorant, wherein the oxidizing agent is free of hydrogen peroxide.

2. The whitening composition according to claim 1, wherein the potassium caroate is present in an amount ranging from about 0.1 wt. % to about 5.0 wt. %, based on the total weight of the whitening composition.

3. The whitening composition according to claim 1 or claim 2, wherein the polymeric fluid comprises a silicone fluid.

4. The whitening composition according to claim 3, wherein the silicone fluid is present in an amount ranging from about 20 wt. % to about 60 wt. %, based on the total weight of the whitening composition.

5. The whitening composition according to any one of claims 1 to 4, wherein the adhesion agent is present in an amount ranging from about 10 wt. % to about 40 wt. %, based on the total weight of the whitening composition.

6. The whitening composition according to any one of claims 1 to 5, wherein the adhesion agent comprises one or more of polyvinyl pyrrolidone, a polyether, or trimethylated silica treated with dimethyl siloxane.

7. The whitening composition according to claim 6, wherein the polyether comprises one or more of polyethylene glycol, polyethylene glycol-polypropylcnc glycol copolymer, or polyoxypropylene-polyoxyethylene block copolymer.

8. The whitening composition according to claim 6 or claim 7, wherein the polyvinyl pyrrolidone is present in an amount ranging from about 1.0 wt. % to about 7.0 wt. %, based on the total weight of the whitening composition.

9. The whitening composition according to any one of claims 6 to 8, wherein the polyether is present in an amount ranging from about 30 wt. % to about 50 wt. %, based on the total weight of the whitening composition.

10. The whitening composition according to any one of claims 1 to 9, further comprising fumed silica.

11. The whitening composition according to claim 10, wherein the fumed silica is present in an amount ranging from about 1 wt. % to about 5 wt. %, based on the total weight of the whitening composition.

12. The whitening composition according to any one of claims 1 to 11, further comprising sodium tripolyphosphate.

13. The whitening composition according to claim 12, wherein the sodium tripolyphosphate is present in an amount ranging from about 1 wt. % to about 4 wt. %, based on the total weight of the whitening composition.

14. The whitening composition according to any one of claims 1 to 13, wherein the flavorant comprises one or more of sodium saccharin, sucralose, and a sensate.

15. The whitening composition according to any one of claims 1 to 14, wherein the flavorant is present in an amount ranging from about 0.1 wt. % to about 2 wt. %, based on the total weight of the whitening composition.

16. A whitening composition comprising; a first whitening component comprising: an oxidizing agent comprising potassium caroate; a carrier comprising a polymeric fluid; a flavorant; a second whitening component comprising: an alkali component; and wherein the first whitening component and the second whitening component are present in a weight ratio ranging from about 1:3 to about 3:1.

17. The whitening composition according to claim 16, wherein the second whitening component is substantially free, optionally free, of hydrogen peroxide.

18. The whitening composition according to claim 16 or claim 18, wherein the whitening composition has a pH ranging from 8 to about 11.

19. The whitening composition according claim 16 to claim 18 further comprising an adhesion agent, wherein the adhesion agent comprises one or more of a polyvinyl pyrrolidone and a polyether.

20. The whitening composition according to claim 19, wherein the polyether is present in an amount ranging from about 15 wt. % to about 25 wt. %, based on the total weight of the first whitening component.

21. The whitening composition according to any one of claims 16 to 20, wherein the alkali component comprises one or more of sodium bicarbonate and sodium carbonate wherein thealkali component comprises sodium bicarbonate and sodium carbonate in a weight ratio ranging from about 6:1 to about 12:1, preferably about 8:1 to about 9:1.

22. The whitening composition according to any one of claims 16 to 21, wherein the weight ratio of the first whitening component and the second whitening component is about 1:1.

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