COMPOSITION BASED ON TRANS-RESVERATROL OR A TRANS-RESVERATROL DERIVATIVE.

A sunscreen composition with a blend of UVA and UVB filters and inorganic filters addresses the challenge of protecting against UV rays and maintaining trans-resveratrol stability, achieving high SPF and minimal degradation.

FR2999911B1Active Publication Date: 2025-10-10LOREAL SA
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Patent Information

Application Number
FR2012062604
Authority / Receiving Office
FR · FR
Patent Type
Patents
Current Assignee / Owner
Filing Date
2012-12-21
Publication Date
2025-10-10
Estimated Expiration
2032-12-21

AI Technical Summary

Technical Problem

Existing sunscreen compositions face challenges in providing effective protection against both UVA and UVB rays while maintaining the stability of active ingredients like trans-resveratrol, which degrades upon exposure to sunlight.

Method used

A composition comprising a mixture of specific UVA and UVB filters, including phenyl benzotriazole derivatives and bis-resorcinyl triazine derivatives, along with inorganic filters like titanium dioxide, is formulated to enhance protection and stability, with a focus on maintaining the efficacy of trans-resveratrol.

Benefits of technology

The composition achieves high SPF values and minimal degradation of trans-resveratrol, ensuring effective sun protection and preserving the active ingredient's potency.

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Abstract

The invention relates to a cosmetic or dermatological composition comprising, in a physiologically acceptable medium, at least trans-resveratrol and / or at least one trans-resveratrol derivative, and an organic filtering system comprising at least one UVA filter and at least one UVB filter and / or at least one mixed UVA-UVB filter, said composition having an SPF greater than or equal to 15 and a PPD greater than or equal to 5. The invention also relates to a use of a filtering system comprising at least one UVA filter and at least one UVB filter and / or at least one mixed UVA-UVB filter for stabilizing, in particular photostabilizing, a composition comprising trans-resveratrol and / or at least one trans-resveratrol derivative.
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Description

Mixed UVA and UVB filters Said at least one mixed UVA-UVB filter can be chosen from the following filters. 1) Mixed hydrophobic UVA and UVB filters Benzophenone derivatives Benzophenone-1 sold in particular under the trade name “UVINUL 400” by BASF; Benzophenone-2 sold in particular under the trade name “UVINUL D50” by BASF; Benzophenone-3 or Oxybenzone sold in particular under the trade name “UVINUL M40” by BASF; Benzophenone-6 sold in particular under the trade name “Helisorb 11” by Norquay; Benzophenone-8 sold in particular under the trade name “Spectra-Sorb UV-24” by American Cyanamid; Benzophenone-10; Benzophenone-11; Benzophenone-12; Phenyl benzotriazole derivatives: Drometrizole Trisiloxane sold in particular under the name “Silatrizole” by RHODIA CHIMIE or manufactured under the name “Meroxyl XL” by the company CHIMEX; Methylene bis-Benzotriazolyl Tetramethylbutylphenol, sold in solid form, notably under the trade name “MIXXIM BB / 100” by FAIRMOUNT CHEMICAL or in micronized form in aqueous dispersion, notably under the trade name “TINOSORB M” by CIBA SPECIALTY CHEMICALS; Bis-resorcinyl triazine derivatives Bis-Ethylhexyloxyphenol Methoxyphenyl Triazine sold in particular under the trade name “TINOSORB S” by CIBA GEIGY; Benzoxazole derivatives: 2,4-bis-[5-l(dimethylpropyl)benzoxazol-2-yl-(4-phenyl)-imino]-6-(2-ethylhexyl)-imino-1,3,5-triazine sold in particular under the name Uvasorb K2A by Sigma 3V. 2) Mixed UVA and UVB water-soluble filters Benzophenone derivatives containing at least one sulfonic radical such as - Benzophenone-4 sold in particular under the trade name “UVINUL MS 40” by BASF, - Benzophenone-5, and - Benzophenone-9. Preferably, said at least one mixed UVA-UVB filter according to the invention is a hydrophobic filter. In particular, said mixed UVA-UVB filter is chosen from phenyl benzotriazole derivatives and bis-resorcinyl triazine derivatives, preferably it is chosen from drometrizole trisiloxane, bis-ethylhexyloxyphenol methoxyphenyl triazine, and mixtures thereof. Preferably, a composition according to the invention is characterized in that said at least one mixed UVA-UVB filter is present in a content ranging from 1 to 20%, in particular from 1 to 10%, and preferably from 1 to 4% by weight relative to the total weight of the composition. According to a first preferred variant, the composition according to the invention comprises octocrylene, ethylhexyl Salicylate, Butyl Methoxydibenzoylmethane (Avobenzone) with or without TiCE. According to a second preferred variant, the composition according to the invention comprises octocrylene, ethylhexyltriazone (Uvinul Tl50), Drometrizole Trisiloxane (Mexoryl XL), Butyl Methoxydibenzoylmethane (Avobenzone), Terephthalylidene Dicamphor Sulfonic Acid (Mexoryl SX) with or without TiO2. According to a third preferred variant, the composition according to the invention comprises Drometrizole Trisiloxane (Mexoryl XL), ethylhexyl Methoxycinnamate, Terephthalylidene Dicamphor Sulfonic Acid (Mexoryl SX) and TiCL treated, for example with aluminum stearate. According to a fourth preferred variant, the composition according to the invention comprises Drometrizole Trisiloxane (Mexoryl XL), Homosalate, Ethylhexyltriazone (Uvinul T150), Ethylhexyl Salicylate, Bis-Ethylhexyloxyphenol Methoxyphenyl Triazine, Butyl Methoxydibenzoylmethane (Avobenzone), and Terephthalylidene Dicamphor Sulfonic Acid (Mexoryl SX). More particularly, the composition according to the invention comprises the following UV filter mixtures by weight relative to the total weight of the composition: - from 1 to 5% of Butyl Methoxydibenzoylmethane, from 0.1 to 3% of ethylhexyltriazone, from 0.5 to 4% of Terephthalylidene Dicamphor Sulfonic Acid, from 5 to 10% of octocrylene, from 0.5 to 4% of Drometrizole Trisiloxane and from 0.1 to 3% of Tiff relative to the total weight of the composition; - 1 to 5% Butyl Methoxydibenzoylmethane, 3 to 7% Ethylhexyl Salicylate, 0.1 to 3% Ethylhexyltriazone, 1.5 to 6% Terephthalylidene Dicamphor Sulfonic Acid, 1 to 5% Octocrylene, 0.1 to 1% Drometrizole Trisiloxane, 0.1 to 3% Bis-Ethylhexyloxyphenol Methoxyphenyl Triazine and 1 to 3% TiCh relative to the total weight of the composition; - from 5 to 10%, of ethylhexyl Methoxycinnamate, from 10 to 15% of Terephthalylidene Dicamphor Sulfonic Acid, from 0.5 to 4% of Drometrizole Trisiloxane and from 0.1 to 3% of TiCh relative to the total weight of the composition; - from 2 to 6% of Butyl Methoxydibenzoylmethane, from 3 to 7% of Ethylhexyl Salicylate, from 0.1 to 3% of Ethylhexyltriazone, from 1 to 5% of Terephthalylidene Dicamphor Sulfonic Acid, from 1 to 5% of Octocrylene, from 0.1 to 2% of Drometrizole Trisiloxane, from 1 to 5% of Bis-Ethylhexyloxyphenol Methoxyphenyl Triazine and from 3 to 7% of TiCE relative to the total weight of the composition; - 0.1 to 2% Drometrizole Trisiloxane, 4 to 8% Homosalate, 1 to 5% Bis-Ethylhexyloxyphenol Methoxyphenyl Triazine, 2 to 6% Butyl Methoxydibenzoylmethane, 1 to 5% Terephthalylidene Dicamphor Sulfonic Acid, 3 to 7% Ethylhexyl Salicylate, 1 to 5% Ethylhexyltriazone. ADDITIVES The composition according to the invention may also include additives such as, for example, inorganic filters, active ingredients, fillers, fatty substances, polymers, silicones. Inorganic filters The inorganic filters are chosen from coated or uncoated metal oxide pigments whose average primary particle size is preferably between 5 nm and 100 nm (preferably between 10 nm and 50 nm) such as, for example, titanium oxide pigments (amorphous or crystallized in rutile and / or anatase form), iron, zinc, zirconium or cerium which are all well-known UV photoprotective agents per se. Pigments can be coated or uncoated. Coated pigments are pigments which have undergone one or more surface treatments of a chemical, electronic, mechanochemical and / or mechanical nature with compounds as described for example in Cosmetics & Toiletries, February 1990, Vol. 105, p. 53-64, such as amino acids, beeswax, fatty acids, fatty alcohols, anionic surfactants, lecithins, sodium, potassium, zinc, iron or aluminum salts of fatty acids, metal alkoxides (titanium or aluminum), polyethylene, silicones, proteins (collagen, elastin), alkanolamines, silicon oxides, metal oxides or sodium hexametaphosphate. As is known, silicones are organosilicon polymers or oligomers with a linear or cyclic, branched or crosslinked structure, of variable molecular weight, obtained by polymerization and / or polycondensation of suitably functionalized silanes, and consisting essentially of a repetition of main units in which the silicon atoms are linked together by oxygen atoms (siloxane bond), optionally substituted hydrocarbon radicals being directly linked via a carbon atom to said silicon atoms. The term "silicones" also includes the silanes necessary for their preparation, in particular, alkyl silanes. The silicones used for coating the pigments suitable for the present invention are preferably chosen from the group containing alkyl silanes, polydialkylsiloxanes, and polyalkylhydrogensiloxanes. Even more preferably, the silicones are chosen from the group containing octyl trimethyl silane, polydimethylsiloxanes and polymethylhydrogensiloxanes. Of course, metal oxide pigments before their treatment with silicones may have been treated with other surfactants, in particular with cerium oxide, alumina, silica, aluminum compounds, silicon compounds, or their mixtures. Coated pigments are more specifically coated titanium oxides: - silica such as the product "SUNVEIL" from the company IKEDA and the product "Eusolex T-AVO" from the company MERCK - silica and iron oxide such as the product "SUNVEIL F" from the company IKEDA, - silica and alumina such as the products "MICROTITANIUM DIOXIDE MT 500 SA" and "MICROTITANIUM DIOXIDE MT 100 SA" from the company TAYCA, "TIOVEIL" from the company TIOXIDE, and "Mirasun TiW 60" from the company Rhodia, - alumina such as the products "TIPAQUE TTO-55 (B)" and "TIPAQUE TTO-55 (A)" from the company ISHIHARA, and "UVT 14 / 4" from the company KEMIRA, - alumina and aluminum stearate such as the product "MICROTITANIUM DIOXIDE MT 100 TV, MT 100 TX, MT 100 Z, MT-01 from the company TAYCA, the products "Solaveil CT-10 W", "Solaveil CT 100" and "Solaveil CT 200" from the company UNIQEMA, - silica, alumina and alginic acid such as the product "MT-100 AQ" from the company TAYCA, - alumina and aluminum laurate such as the product "MICROTITANIUM DIOXIDE MT 100 S" from the company TAYCA, - iron oxide and iron stearate such as the product "MICROTITANIUM DIOXIDE MT 100 F" from the company TAYCA, - zinc oxide and zinc stearate such as the product "BR351" from the company TAYCA, - silica and alumina and treated with a silicone such as the products "MICROTITANIUM DIOXIDE MT 600 SAS", "MICROTITANIUM DIOXIDE MT 500 SAS" or "MICROTITANIUM DIOXIDE MT 100 SAS" from the company TAYCA, - silica, alumina, aluminum stearate and treated with silicone such as the product "STT-30-DS" from the company TITAN KOGYO, - silica and treated with a silicone such as the product "UV-TITAN X 195" from the company KEMIRA, or the product SMT-100 WRS from the company TAYCA. - alumina and treated with silicone such as the products "TIPAQUE TTO-55 (S)" from the company ISHIHARA, or "UV TITAN M 262" from the company KEMIRA, of triethanolamine such as the product "STT-65-S" from the company TITAN KOGYO, - of stearic acid such as the product "TIPAQUE TTO-55 (C)" from the company ISHIHARA, sodium hexametaphosphate such as the product "MICROTITANIUM DIOXIDE MT 150 W" from the company TAYCA. Other titanium oxide pigments treated with a silicone are preferably TiO2 treated with octyl trimethyl silane and whose average elementary particle size is between 25 and 40 nm such as that sold under the trade name "T 805" by the company DEGUSSA SILICES, TiO2 treated with a polydimethylsiloxane and whose average elementary particle size is 21 nm such as that sold under the trade name "70250 Cardre UF TiO2SI3" by the company CARDRE, anatase / rutile TiO2 treated with a polydimethylhydrogenosiloxane and whose average elementary particle size is 25 nm such as that sold under the trade name "MICRO TITANIUM DIOXIDE USP GRADE HYDROPHOBIC" by the company COLOR TECHNIQUES. Uncoated titanium oxide pigments are, for example, sold by the company TAYCA under the trade names "MICROTITANIUM DIOXIDE MT 500 B" or "MICROTITANIUM DIOXIDE MT600 B", by the company DEGUSSA under the name "P 25", by the company WACKHER under the name "Transparent titanium oxide PW", by the company MIYOSHI KASEI under the name "UFTR", by the company TOMEN under the name "ITS" and by the company TIOXIDE under the name "TIOVEIL AQ". Uncoated zinc oxide pigments, for example, are - those marketed under the name “Z-cote” by the company Sunsmart; - those marketed under the name “Nanox” by the company Elementis; - those marketed under the name “Nanogard WCD 2025” by the company Nanophase Technologies; Coated zinc oxide pigments are for example - those marketed under the name “Z-COTE HP1” by the company SUNSMART (dimethicone-coated ZnO); - those marketed under the name “Oxide zinc CS-5” by the company Toshibi (ZnO coated with polymethylhydrogenesiloxane); - those marketed under the name "Nanogard Zinc Oxide FN" by the company Nanophase Technologies (in 40% dispersion in Finsolv TN, benzoate of C12-C15 alcohols); - those marketed under the name "DAITOPERSION ZN-30" and "D AITOPERSION Zn-5 0" by the company Daito (dispersions in cyclopolymethylsiloxane / oxyethylenated polydimethylsiloxane, containing 30% or 50% of nano-zinc oxides coated with silica and polymethylhydrogensiloxane); - those marketed under the name "NFD Ultrafine ZnO" by the company Daikin (ZnO coated with perfluoroalkyl phosphate and perfluoroalkylethyl copolymer dispersed in cyclopentasiloxane); - those marketed under the name "SPD-Z1" by the company Shin-Etsu (ZnO coated with silicone-grafted acrylic polymer, dispersed in cyclodimethylsiloxane); - those marketed under the name "Escalol Z100" by the company ISP (alumina-treated ZnO dispersed in the mixture of ethylhexyl methoxycinnamate / PVP-hexadecene copolymer / methicone); - those marketed under the name "Fuji ZnO-SMS-10" by the company Fuji Pigment (ZnO coated with silica and polymethylsilsesquioxane); - those marketed under the name "Nanox Gel TN" by the company Elementis (ZnO dispersed at 55% in C12-C15 alcohol benzoate with hydroxystearic acid polycondensate). Uncoated cerium oxide pigments are sold, for example, under the name "COLLOIDAL CERIUM OXIDE" by the company RHONE POULENC. Uncoated iron oxide pigments are sold, for example, by the company ARNAUD under the names "NANOGARD WCD 2002 (FE 45B)", "NANOGARD IRON FE 45 BL AQ", "NANOGARD FE 45R AQ, "NANOGARD WCD 2006 (FE 45R)", or by the company MITSUBISHI under the name "TY-220". Coated iron oxide pigments are sold, for example, by the company ARNAUD under the names "NANOGARD WCD 2008 (FE 45B FN)", "NANOGARD WCD 2009 (FE 45B 556)", "NANOGARD FE 45 BL 345", "NANOGARD FE 45 BL", or by the company BASF under the name "TRANSPARENT IRON OXIDE". Mention may also be made of mixtures of metal oxides, in particular titanium dioxide and cerium dioxide, including the equal-weight mixture of titanium dioxide and cerium dioxide coated with silica, sold by the company IKEDA under the name "SUNVEIL A", as well as the mixture of titanium dioxide and zinc dioxide coated with alumina, silica and silicone such as the product "M 261" sold by the company KEMIRA or coated with alumina, silica and glycerin such as the product "M 211" sold by the company KEMIRA. Composite particles The composition according to the invention may also comprise, as inorganic filters, composite particles. The composite particles usable according to the present invention comprise a matrix and an inorganic UV filter. The matrix comprises one or more organic and / or inorganic materials. The inorganic UV filter is generally chosen from metal oxides. According to a preferred variant, the matrix is ​​essentially made up of organic and / or inorganic material. The inorganic materials usable in the matrix according to the present invention are chosen from the group formed by mica, synthetic mica, talc, serecite, boron nitride, glass, calcium carbonate, barium sulfate, hydroxyapatite, silica, silicate, magnesium sulfate, magnesium carbonate, magnesium trisilicate magnesium, aluminum oxide, aluminum silicate, calcium silicate, calcium phosphate, magnesium oxide, bismuth oxychloride, kaolin, hydrotalcite, mineral clays, synthetic clays and mixtures thereof. The organic materials that can be used to form the matrix are chosen from the group formed by poly(meth)acrylates, polyamides, silicones, polyurethanes, polyethylenes, polypropylenes, polystyrenes, polyhydroxyalkanoates, polycaprolactams, poly(butylene)succinates, polysaccharides, polypeptides, polyvinyl alcohols, polyvinyl resins, fluoropolymers, waxes, polyesters, polyethers, and their mixtures. The inorganic UV filters that can be used in the composite particle are chosen from metal oxides. Preferably, these metal oxides are chosen from titanium dioxide TiCL, zinc oxide ZnO, and iron oxide FeO. Particularly preferably, the inorganic UV filter is TiO2. These metal oxides can be in the form of particles, with an average size generally less than 0.2 pm. Advantageously, the TiO2 particles used have an average size less than or equal to 0.1 pm. These metal oxides can also be in the form of layers, preferably multilayers with an average thickness generally less than 0.2 pm. Preferably, the content of composite particles in the composition according to the invention ranges from 1 to 70%, preferably 1.5 to 45%, preferably from 2 to 20% by weight relative to the total weight of the cosmetic composition. The composite particles that can be used according to the invention are preferably spherical. They can be hollow, smooth, rough, or porous. When the composite particles are in spherical form, they are characterized by an average diameter of between 0.1 pm and 30 pm, preferably between 0.2 pm and 20 pm and more preferably between 0.3 pm and 10 pm, advantageously between 0.5 pm and 10 pm. By "spherical" we mean that the particle has a sphericity index, that is to say the ratio between its largest diameter and its smallest diameter, of less than 1.2. Shapes of composite particles According to a first variant, the composite particles contain a matrix comprising an organic and / or inorganic material in which are included inorganic UV filter particles. Preferably, the composite particles consist of a matrix comprising an organic and / or inorganic material in which inorganic UV filter particles are included. In this embodiment, the matrix has inclusions and inorganic UV filter particles are placed in the inclusions of the matrix. Preferably, the composite particles are spherical and have inclusions in which inorganic UV filter particles are placed. As composite particles corresponding to this variant, we can cite the products Sunsil TIN 50 and Sunsil TIN 40 marketed by the company SUNJIN CHEMICAL. These spherical composite particles of average size between 2 and 7 pm are formed of TiCL encapsulated in a silica matrix. According to a second variant, the composite particles contain a matrix of an organic and / or inorganic material covered with at least one layer of inorganic UV filter which can be connected to the matrix using a binder. According to this second variant, the matrix particles are preferably spherical in shape. According to this second variant, the average thickness of the inorganic UV filter layer is generally around ten nanometers. The average thickness of the inorganic UV filter layer is advantageously between 10'3 and 0.2 pm, preferably between 10'2 and 0.2 pm. According to a third variant, the composite particles contain an inorganic UV filter covered with at least one layer of an organic and / or inorganic material. According to this third variant, the inorganic UV filter particles are characterized by an average elementary size generally between 10'3 and 0.2 pm. Advantageously, the metal oxide particles used have an average elementary size between 10' and 0.1 pm. The matrix may be formed from one or more organic or inorganic materials. It may then be a continuous phase of materials such as an alloy, i.e. a continuous phase in which the materials are no longer dissociable, or a discontinuous phase of materials, for example consisting of an organic or inorganic material covered with a layer of another different organic or inorganic material. According to a variant, in particular when the composite particles comprise a matrix coated with a UV filter layer, the composite particles can furthermore be covered with an additional coating in particular chosen from biodegradable or biocompatible materials, lipid materials such as surfactants or emulsifiers, polymers, and oxides. The composite particles used according to the invention have a size between 0.1 and 30 pm, preferably between 0.5 and 20 pm and more preferably between 0.3 and 10 pm, advantageously between 0.5 and 10 pm. Preferably, the UV filter used in the composite particle is TiO2 or a mixture of TiO2 and ZnO. Preferably, the matrix of the spherical composite particle contains a material or a mixture of materials chosen from: - SiO2, - polymethyl methacrylate, - copolymers of styrene and a C1 / C5 alkyl (meth)acrylate derivative, - polyamides such as nylons. As composite particles corresponding to this variant, we can cite the products Sunsil TIN 50 and Sunsil TIN 40 marketed by the company SUNJIN CHEMICAL. These spherical composite particles of average size between 2 and 7 pm are formed of TiO2 encapsulated in a silica matrix. We can also cite the following particles: - Spherical composite particles of average size between 4 and 8 pm, containing TiO2 and SiO2 under the trade name Eospoly TR marketed by the company CREATIONS COULEURS, - Composite particles containing TiO2 and a styrene / alkyl acrylate copolymer matrix marketed under the name Eospoly UV TR22 HB 50 by the company CREATIONS COULEURS, - Composite particles containing TiO2 and ZnO and a PMMA matrix with the trade name Sun PMMA-T50 marketed by the company SUNJIN CHEMICAL. Among the composite particles that can be used according to the invention, mention may also be made of spherical composite particles containing TiO2 and SiO2 with the trade name STM ACS-0050510, supplied by the company JGC Catalysts and Chemical. Preferably, the inorganic filters are chosen from titanium dioxide, optionally coated with aluminum hydroxide and stearic acid, titanium dioxide optionally coated with stearic acid and alumina and mixtures thereof. According to a particular embodiment of the invention, the at least one inorganic filter is present in the composition according to the invention in a content ranging from 0.01 to 20% by weight, preferably from 0.1 to 10% by weight, preferably from 0.5 to 7% by weight, and in particular from 0.8 to 6% by weight relative to the total weight of the composition. The compositions in accordance with the present invention may also comprise conventional cosmetic adjuvants, in particular chosen from organic solvents, ionic or non-ionic, hydrophilic or lipophilic thickeners, softeners, humectants, opacifiers, stabilizers, emollients, silicones, anti-foaming agents, perfumes, preservatives, anionic, cationic, non-ionic, zwitterionic or amphoteric surfactants, fillers, polymers, propellants, alkalizing or acidifying agents or any other ingredient usually used in the cosmetic and / or dermatological field. Organic solvents include lower alcohols and polyols. These may be selected from glycols such as propylene glycol, butylene glycol, dipropylene glycol, glycerin, 1,3-propanediol, pentyl glycol or hexylene glycol. Examples of hydrophilic thickeners include carboxyvinyl polymers such as Carbopols (Carbomers) and Pemulen (acrylate / C10-C30 alkylacrylate copolymer); polyacrylamides such as crosslinked copolymers sold under the names Sepigel 305 (CTFA name: polyacrylamide / C13-C14 isoparaffin / Laureth 7) or Simulgel 600 (CTFA name:: acrylamide / sodium acryloyldimethyltaurate copolymer / isohexadecane / polysorbate 80) by the company Seppic; polymers and copolymers of 2-acrylamido 2-methylpropane sulfonic acid, optionally crosslinked and / or neutralized, such as Poly(2-acrylamido 2-methylpropane sulfonic acid) marketed by Hoechst under the trade name “Hostacerin AMPS” (CTFA name: ammonium polyacryloyldimethyl taurate or SIMULGEL 800 marketed by SEPPIC (CTFA name: sodium polyacryolyldimethyl taurate / polysorbate 80 / sorbitan oleate); copolymers of 2-acrylamido 2-methylpropane sulfonic acid and hydroxyethyl acrylate such as SIMULGEL NS and SEPINOV EMT 10 marketed by SEPPIC; cellulose derivatives such as hydroxyethylcellulose; polysaccharides and in particular gums such as xanthan gum; and mixtures thereof. Lipophilic thickeners include synthetic polymers such as poly C10-C30 alkyl acrylates sold under the name "INTELIMER IPA 13-1" and "INTELIMER IPA 13-6" by Landec, or modified clays such as hectorite and its derivatives, such as products sold under the name Bentone. Of course, those skilled in the art will take care to choose the possible additional compound(s) mentioned above and / or their quantities in such a way that the advantageous properties intrinsically attached to the compositions in accordance with the invention are not, or not substantially, altered by the addition(s) envisaged. The compositions according to the invention can be prepared according to techniques well known to those skilled in the art. They can be presented in particular in the form of a direct, inverse or multiple emulsion (O / W, W / O, O / W / O or W / O / W). They can optionally be packaged as an aerosol and be presented in the form of a spray. Preferably, the compositions according to the invention are in the form of an oil-in-water or water-in-oil emulsion and more particularly oil-in-water emulsions. Emulsions generally contain at least one emulsifier chosen from amphoteric, anionic, cationic or non-ionic emulsifiers, used alone or in a mixture. The emulsifiers are chosen appropriately depending on the emulsion to be obtained (W / O or O / W). Emulsions may also contain other types of stabilizers such as fillers, gelling or thickening polymers. Examples of emulsifying surfactants that can be used for the preparation of W / O emulsions include alkyl esters or ethers of sorbitan, glycerol or sugars; silicone surfactants such as dimethicone copolyols such as the mixture of dimethicone and PEG / polypropylene glycol (PPG) 18 / 18 dimethicone, sold under the name "X-22-6711D" by the company Shin Etsu, and alkyl-dimethicone copolyols such as Laurylmethicone copolyol sold under the name "Dow Corning 5200 Formulation Aid" by the company Dow Corning; Cetyl dimethicone copolyol such as the product sold under the name Abil EM 90R by the company Goldschmidt and the mixture of cetyl dimethicone copolyol, polyglycerol isostearate (4 moles) and hexyl laurate sold under the name ABIL WE 09 by the company Goldschmidt. One or more co-emulsifiers may also be added, which, advantageously, may be chosen from the group comprising polyol alkyl esters or emulsifying silicone elastomers such as the mixture of dimethicone and dimethicone / PEG-10 / 15 crosslinked polymer sold under the name “KSG-210”. Examples of polyol alkyl esters include polyethylene glycol esters such as PEG-30 Dipolyhydroxystearate, such as the product marketed under the name Arlacel P135 by the company ICI. Examples of glycerol and / or sorbitan esters that may be mentioned include polyglycerol isostearate, such as the product marketed under the name Isolan GI 34 by the company Goldschmidt; sorbitan isostearate, such as the product marketed under the name Arlacel 987 by the company ICI; sorbitan isostearate and glycerol, such as the product marketed under the name Arlacel 986 by the company ICI, and mixtures thereof. For HZE emulsions, examples of emulsifiers that may be mentioned include non-ionic emulsifiers such as oxyalkylenated (more particularly polyoxyethylenated) fatty acid esters of glycerol; oxyalkylenated (oxyethylenated and / or oxypropylenated) fatty acid esters of sorbitan; oxyalkylenated (oxyethylenated and / or oxypropylenated) fatty acid esters such as the PEG-100 Stearate / Glyceryl Stearate mixture marketed, for example, by the company ICI under the name Arlacel 165; oxyalkylenated (oxyethylenated and / or oxypropylenated) fatty alcohol ethers; sugar esters such as sucrose stearate;fatty alcohol and sugar ethers, in particular alkylpolyglucosides (APG) such as decylglucoside and laurylglucoside marketed for example by Henkel under the respective names Plantaren 2000 and Plantaren 1200, cetostearylglucoside possibly in a mixture with cetostearyl alcohol, marketed for example under the name Montanov 68 by Seppic, under the name Tegocare CG90 by Goldschmidt and under the name Emulgade KE3302 by Henkel, as well as arachidyl glucoside, for example in the form of the mixture of arachidic and behenic alcohols and arachidylglucoside marketed under the name Montanov 202 by Seppic. According to a particular embodiment of the invention, the mixture of the alkylpolyglucoside as defined above with the corresponding fatty alcohol may be in the form of a self-emulsifying composition, as described for example in document WO-A-92 / 06778. ; The following examples illustrate the invention without limiting its scope. In the description and examples, the percentages are by weight. The ingredients are mixed in the order and under the conditions easily determined by those skilled in the art. Examples 5 Example 1: Compositions in accordance with the invention The compositions are prepared by mixing the following ingredients: Nom INCI Composition 1 (% en poids) Composition 2 (% en poids) Composition 3 (% en poids) Composition 4 (% en poids) Disodium EDTA 0,1 0,1 0,1 Tocopherol 0,5 0,5 0,5 Triethanoalmine 0,33 0,85 0,07 0,59 Conservateur 1 1 1 1 Octyldodecanol 2 2 2 Cetearyl alcohol 1 1 1 1 Diisopropyl sebacate 3 5 Resveratrol 0,25 0,25 0,25 0,25 Ethylhexyl methoxycinnamate 7,5 Butyl methoxydibenzoyl methane 2,5 3 3,5 Ethylhexyl salicilate 5 5 Ethylhexyl triazone 1 1 1 Terephtalylidene dicamphor sulfonic acid 1,5 4.5 12 3 Octocrylene 7 2,5 2,5 Drometrizole trisiloxane 1,5 0,5 1,5 0,5 Bis-ethylhexyloxyphen ol methoxyphenyl triazine 1 3 INCI name Composition 1 (% by weight) Composition 2 (% by weight) Composition 3 (% by weight) Composition 4 (% by weight) Titanium dioxide (and) aluminum hydroxide (and) stearic acid 1 2 1 5 Cyclohexasiloxane 1 1 Dimethicone (and) dimethiconol 3 3 3 3 Alcohol denat. 5 5 5 5 Glycerin 4 4 4 4 Propylene glycol 8 8 8 8 Stearic acid 2 2 2 2 Glyceryl stearate (and) PEG-100 stearate 2 2 2 2 PEG-20 stearate 0.8 0.8 0.8 0.8 Water QsplOO QsplOO QsplOO QsplOO The emulsions of compositions 1 to 4 are fine, homogeneous, shiny, smooth and stable over time. Example 2: Compositions not in accordance with the invention INCI Name Composition 5 (% by weight) Composition 6 (% by weight) Composition 7 (% by weight) Composition 8 (% by weight) Disodium EDTA 0.1 0.1 0.1 0.1 Tocopherol 0.5 0.5 0.5 0.5 Triethanoalmine 0.07 1.58 0.07 0.07 Citric Acid 0.528 Silica 0.5 0.5 0.5 0.5 Preservative 1 1 1 1 Nom INCI Composition 5 (% en poids) Composition 6 (% en poids) Composition 7 (% en poids) Composition 8 (% en poids) Octyldodecanol 2 2 2 2 Cetearyl alcohol 1 1 1 1 Isopropyl lauroyl sarcosinate 7.5 Resveratrol 0,25 0,25 0,25 0,25 Phenylbenzimida-zole sulfonic acid 1,7 Ethylhexyl salicilate 5 Terephtalylidene dicamphor sulfonic acid 0,15 Octocrylene 7 Bis-ethylhexyloxyphen ol methoxyphenyl triazine 1 Butyl methoxydibenzoyl méthane 3 Ethylhexyl methoxycinnamate 7,5 Titanium dioxide (and) stearic acid (and) alumina 1 Xanthan gum 0,2 0,2 0,2 0,2 Ammonium polyacryloyldimeth yl taurate 1,7 1,7 1,7 1,7 Cyclohexasiloxane 1 5 1 5 Dimethicone (and) dimethiconol 3 3 3 3 Alcohol denat. 5 5 5 5 Glycerin 4 4 4 4 Nom INCI Composition 5 (% en poids) Composition 6 (% en poids) Composition 7 (% en poids) Composition 8 (% en poids) Stearic acid 2 2 2 2 Glyceryl stéarate (and) PEG-100 stéarate 2 2 2 2 PEG-20 stéarate 0,8 0,8 0,8 0,8 Water QsplOO QsplOO QsplOO QsplOO Example 3: Characteristics of compositions 1 to 8 Compositions in accordance with the invention Compositions not in accordance with the invention 1 2 3 4 5 6 7 8 Quantity of UVA filter (% by weight) 4 7.5 12 6.5 0 0.15 3 3 Quantity of UVB filter (% by weight) 9.5 9 9 9 0 9.2 12 10 SPF 20 30 50 50 / 15 25 20 PPD 8 20 20 30 / 1 1 1 SPF / PPD ratio 2.5 1.5 2.5 1.67 / 15 25 20 % residual trans-resveratrol (i) 86 86 89 90 <5 31 47 35 (1)The residual percentage of resveratrol is measured after exposure of the composition to 5 J / cm2 of UV, which corresponds to a daily dose. 5 The four compositions in accordance with the invention (compositions 1 to 4) have a very high residual percentage of resveratrol after exposure of the composition to 5 J / cm2 of UV, which means that the latter degrades very little on contact with daylight. 10 When the composition does not include a UV filter (composition 5), the degradation of resveratrol after exposure of the composition to 5 J / cm2 of UV, is almost total which means that the latter degrades a lot on contact with daylight. When the composition has a low UVA sun protection factor (PPD) (compositions 6, 7 and 8), a significant degradation of the transis resveratrol is also observed.

Claims

AMENDED CLAIMS 1. Cosmetic or dermatological composition comprising, in a physiologically acceptable medium, at least trans-resveratrol and / or at least one trans-resveratrol derivative, and an organic filtering system comprising at least one UVA filter and at least one UVB filter and / or at least one mixed UVA-UVB filter, said composition having an SPF greater than or equal to 15 and a PPD greater than or equal to 5, and said UVA filter being a water-soluble UVA filter.

2. Composition according to claim 1, wherein said trans-resveratrol and / or trans-resveratrol derivative(s) is present in a content ranging from 0.001 to 10%, preferably from 0.01 to 5% by weight, more preferably from 0.05 to 2% by weight relative to the total weight of the composition.

3. Composition according to claim 1 or 2, characterized in that the SPF / PPD ratio ranges from 1 to 3, preferably from 1.3 to 2.7 and better still from 1.5 to 2.

5.

4. Composition according to any one of the preceding claims, characterized in that said at least one UVA filter is chosen from water-soluble camphor derivatives.

5. Composition according to any one of the preceding claims, characterized in that said at least one UVA filter is terephthalylidene dicamphor sulfonic acid.

6. Composition according to any one of the preceding claims, characterized in that it further comprises at least one UVA filter chosen from hydrophobic derivatives of dibenzoylmethane, preferably butyl methoxydibenzoylmethane.

7. Composition according to any one of the preceding claims, characterized in that said at least one UVA filter is present in a content ranging from 1 to 20% and in particular from 2 to 15% by weight relative to the total weight of the composition.

8. Composition according to claim 1 to 3, characterized in that said at least one UVB filter is a hydrophobic UVB filter.

9. Composition according to claim 1, 2, 3 or 8, characterized in that said at least one hydrophobic UVB filter is chosen from salicylic derivatives, cinnamates, P,P'-diphenylacrylate derivatives, triazine derivatives and mixtures thereof.

10. Composition according to claim 1, 2, 3, 8 or 9, characterized in that said at least one UVB filter is chosen from ethylhexyl salicylate, ethylhexyl methoxycinnamate, octocrylene, ethylhexyl triazone and mixtures thereof.

11. Composition according to any one of the preceding claims 1 to 3 or 8 to 10, characterized in that said at least one UVB filter is present in a content ranging from 1 to 20%, in particular from 5 to 15% and preferably from 7 to 10% by weight relative to the total weight of the composition.

12. Composition according to any one of the preceding claims, characterized in that said organic filtering system comprises at least one mixed UVA-UVB filter, preferably chosen from hydrophobic mixed UVA-UVB filters.

13. Composition according to the preceding claim, characterized in that the hydrophobic mixed UVA-UVB filter is chosen from phenyl benzotriazole derivatives and bis-resorcinyl triazine derivatives, preferably from drometrizole trisiloxane, bis-ethylhexyloxyphenol methoxyphenyl triazine, and mixtures thereof.

14. Composition according to any one of the preceding claims, characterized in that it is in the form of an oil-in-water or water-in-oil emulsion and more particularly oil-in-water emulsions.

15. A method of stabilizing, in particular photostabilizing, a composition comprising trans-resveratrol and / or at least one trans-resveratrol derivative comprising a step during which an organic filtering system comprising at least one UVA filter and at least one UVB filter and / or at least one mixed UVA-UVB filter is added to said composition, said UVA filter being a water-soluble UVA filter, in an amount such that the SPF of the composition is brought to a value greater than or equal to 15 and the PPD of the composition is brought to a value greater than or equal to 5.

16. Use of a filtering system comprising at least one UVA filter and at least one UVB filter and / or at least one mixed UVA-UVB filter, said UVA filter being a water-soluble UVA filter, to stabilize in particular photostabilize a composition comprising trans-resveratrol and / or at least one trans-resveratrol derivative.