MODULAR COMBINED MASK DEVICE FOR FACIAL DIAGNOSIS AND TREATMENT

Abstract

MODULAR COMBINATION MASK DEVICE FOR FACIAL DIAGNOSIS AND TREATMENT. Portable modular mask systems for combined facial and skin care diagnosis and therapy. The systems include devices that can be attached to wearable masks for the diagnosis and treatment of skin conditions, diseases, and disorders, as well as for cosmetic enhancements of facial and scalp skin. Figure for abstract: none

Description

Title of the invention: MODULAR COMBINED MASK DEVICE FOR FACIAL DIAGNOSIS AND TREATMENT SUMMARY

[0001] In one aspect, the disclosure proposes a modular mask system configured for cosmetic analysis and treatment, the modular mask system comprising: a portable modular mask, comprising: a front portion attached to a rear portion which includes a grid system configured for cosmetic analysis, cosmetic treatment, or both; a template configured to accept and guide a printer device for the application of a cosmetic style to a portion of the individual's skin that is adjacent to the template; and an attachment site configured to accept and position a therapy device for the application of a cosmetic treatment to a portion of the individual's skin that is adjacent to the attachment site.

[0002] In some embodiments, the modular mask system further includes the printer device.

[0003] In some embodiments, the modular mask system further includes the therapy device.

[0004] In embodiments, the modular mask system further includes control circuitry configured to control one or more analyses and / or cosmetic treatments.

[0005] In embodiments, the modular mask system further includes a computer device comprising circuitry configured to interact with the control circuitry for the coordination, observation or management of cosmetic analysis and processing by the computer device.

[0006] In some embodiments, the computing device includes a smartphone, a tablet, a laptop, a desktop computer, a smartwatch, a portable computing device, or any combination thereof.

[0007] In embodiments, the portable modular mask includes a lower detachment point at which an eye portion of the portable modular mask is detachable from a mouth portion of the portable modular mask.

[0008] In embodiments, the modular mask system further includes a scalp portion of the wearable modular mask, wherein a rear portion of the scalp portion includes a grid system configured for cosmetic analysis, cosmetic treatment, or both.

[0009] In embodiments, the portable modular mask includes a top detachment point at which the scalp portion of the portable modular mask is detachable from an eye portion of the portable modular mask.

[0010] In embodiments, the modular mask system includes circuitry configured for cosmetic analysis of a portion of the individual's skin based on a feature of the skin portion.

[0011] In embodiments, the modular mask system includes circuitry configured to interact with a computer device which includes circuitry configured for cosmetic analysis of a portion of the individual's skin based on a feature of the skin portion.

[0012] In embodiments, the grid system is configured for optical characterization of a portion of the individual's skin, electrical characterization of a portion of the individual's skin, light therapy, microcurrent therapy, radiofrequency (RF) heating therapy, cold plasma therapy, acoustic energy therapy, or any combination thereof.

[0013] In embodiments, the printer device is configured for precise application of makeup to a portion of the individual's eyebrow.

[0014] In embodiments, the modular mask system further includes an orifice configured to accept at least a portion of a smartphone lens for smartphone-facilitated imaging of at least a portion of the individual's face with placement of the wearable modular mask on it via smartphone camera circuitry.

[0015] In embodiments, the fixing site is positioned at the level of a portion of the cheek of the portable modular mask.

[0016] The purpose of this summary is to present a selection of concepts in a simplified form, which are described in greater detail below in the detailed description. This summary is not intended to identify key features of the claimed subject matter, nor is it intended to be used as an aid in determining the scope of the claimed subject matter. Description of the drawings

[0017] [Fig.1A] Fig.1A shows a front view of an example of a portable modular mask system, according to aspects of disclosure.

[0018] [Fig.1B] Fig.1B shows a rear view of an example of a portable modular mask system, according to aspects of disclosure.

[0019] [Fig.2A] Fig.2A shows a front view of the first example of a portable modular mask system with an eye portion detached from a mouth portion, according to aspects of disclosure.

[0020] [Fig.2B] Fig.2B shows a rear view of the first example of a portable modular mask system with the eye portion detached from the mouth portion, according to aspects of disclosure.

[0021] [Fig.3A] Fig.3A shows a front view of a second example of a portable modular mask system, according to aspects of disclosure.

[0022] [Fig.3B] Fig.3B shows a rear view of the second example of a portable modular mask system, according to aspects of disclosure.

[0023] [Fig.4A] Fig.4A shows a front view of the second example of a wearable modular mask system with the eye portion detached from the mouth portion and a scalp portion detached from the eye portion, according to aspects of the disclosure.

[0024] [Fig.4B] Fig.4B shows a rear view of the second example of a wearable modular mask system with the eye portion detached from the mouth portion and the scalp portion detached from the eye portion, according to aspects of the disclosure.

[0025] [Fig.5] The [Fig.5] shows a diagram of an example of a portable modular mask system, including examples of device attachments configured for at least one light therapy, microcurrent therapy, radio frequency (RF) electric current heating therapy, cold plasma therapy, acoustic energy therapy, or any combination thereof, according to aspects of disclosure.

[0026] [Fig.6] The [Fig.6] shows a diagram of an example of a portable modular mask system configured for usable interaction with an intelligent device, such as a smartphone, according to aspects of disclosure.

[0027] [Fig.7A] Fig.7A represents a perspective view of the underside of an example of a printer device for applying a cosmetic style to a portion of an individual's skin.

[0028] [Fig.7B] The [Fig.7B] shows a top rear perspective view of the example printer device.

[0029] [Fig.8A] Fig.8A shows a top exploded view of the example printer device.

[0030] [Fig.8B] The [Fig.8B] represents a lower exploded view of the example printer device.

[0031] [Fig.9] Fig.9 shows a perspective view of an example capsule applicator, according to aspects of disclosure.

[0032] [Fig. 10] The [Fig. 10] shows a cross-sectional view of an example of an applicator capsule, according to aspects of disclosure.

[0033] [Fig. 11] The [Fig. 11] shows a cross-sectional view of an example of an applicator capsule, according to aspects of disclosure.

[0034] [Fig. 12] The [Fig. 12] shows an example of a formula and system cartridge, according to aspects of disclosure.

[0035] [Tables 1] Numerical Reference Description 1 Modular Mask System 2 Portable Modular Mask 3 Template 4 Lower Detachment Point 4a Lower Eye Portion Attachment Point 4b Upper Mouth Portion Attachment Point 5a Attachment Site (Right) 5b Attachment Site (Left) 6a Eye Orifice (Right) 6b ​​Eye Orifice (Left) 7 Nose Orifice 8 Mouth Orifice 9 Eye Portion 10 Mouth Portion 11 Grid System 12 Upper Detachment Point 12a Lower Scalp Portion Attachment Point 12b Upper Eye Portion Attachment Point 13 Scalp Portion 14a Therapy Device (Right) 14b Therapy Device (Left) 15 Printer Device 16a Light Therapy 16b Microcurrent Therapy 16c Radiofrequency (RF) Warming Therapy 16d Cold plasma treatment 16e Acoustic therapy 17 Smart device

[0036] [Tables2] Numerical Reference Description 100 Printer Device 105 Housing 110 Printer 112 Printer Applicator 114A Spacer 114B Spacer 115 Position Sensor 125 Processor 130A Light Source 130B Light Source 135 Handle 140 Display 145 Tank 150 Internal Component 160 Flexible Connector

[0037] [Tables3] Numerical Reference Description 100 Applicator Capsule 110 Rolling Ball 111 Rolling Ball Orifice 112 Formula Cartridge 113 Formula Cartridge Microchip 120 Contact Face 121 Electrode Orifice 130a Electrode 130b Electrode 130c Electrode 130d Electrode 140 Insert 141 Adapter 142a Locking groove 142b Locking groove 150 Electrode contact 160 Adapter 161a Orifice (outer portion) 161b Orifice (inner portion) 162 Interior 200 Body 201 Insert attachment 202 Body surface 203 Tank attachment 204 Tank 205a On button / control 205b Eject button / control 207 Orifice 208 Electrical connection 900 Microcurrent system

[0038] The foregoing aspects and many associated advantages of the present invention will be more easily appreciated as they are better understood with reference to the detailed description that follows, when taken in conjunction with the accompanying drawings. Detailed description

[0039] Consumers of facial and head skincare devices for diagnosis and / or treatment typically own multiple devices, each of which only meets a subset of the individual's total skincare needs. The individual must therefore generally purchase and manage multiple devices, including maintenance, repairs, and replacement of consumables. for these devices. In addition, at least some cosmetic devices can be difficult to use accurately and consistently, leading to frustration.

[0040] Consequently, there is a need for a facial and scalp skincare platform that combines multiple diagnostics and cosmetic treatments for greater convenience, ease of use, accuracy, and consistency in diagnostics and cosmetic treatments. The present disclosure addresses these and other long-unmet needs in the technology. MODULAR MASK SYSTEMS

[0041] As shown by way of non-limiting example in [Fig. 5], an example of a wearable modular mask system 1 may include and / or be compatible with various examples of device attachments (e.g., 14a, 14b, 15) configured for at least one light therapy, microcurrent therapy, radiofrequency (RF) electric current heating therapy, cold plasma therapy, acoustic energy therapy, or any combination thereof, according to aspects of the disclosure. The devices may provide one or more diagnostic and / or treatment modalities and may be reversibly or temporarily attached to the wearable mask, which may hold the devices in a relatively fixed, controlled, or limited position relative to the user's face for consistent and reliable diagnostics and treatments.Because the positions of the devices relative to the individual's face are more consistent or reproducible, the devices may not necessarily need to make as many physical adjustments in positioning for diagnostics and / or treatments, and the processing power required for diagnostics and / or treatments may be reduced, leading to a more efficient system.

[0042] The disclosure proposes modular mask systems that are configured for use by consumers at home or in their own space, without necessarily requiring a visit to a clinic or spa. The systems can visually map a user's face (e.g., generating an individual's profile) and can identify treatment areas. Devices can "snap" onto a mask of the system for use; for example, a snap-on skin-printing module, a snap-on LED therapy module, and the like. For LED therapy, an LED light therapy device can be plugged into the mask and connected to a plurality of waveguides that deliver light to the appropriate areas.The LED light does not need to be moved; it remains static, relative to the user's face, and the light is delivered through waveguides (which can be arranged as a grid system, as described here) for the delivery of light to all or many portions of the user's facial and / or scalp skin. ci. Since the wearable mask includes eye holes and, optionally, mouth and / or nose holes, the mask can be worn daily with minimal interruption. In some embodiments, the mask system may have a Peltier heating and / or cooling system (e.g., heating, cooling, or both). In some embodiments, the mask system may be configured to facilitate interaction with a virtual reality (VR) and / or augmented reality (AR) system or device by a user of the mask system while it is being worn.

[0043] As shown by way of non-limiting examples in Figures 1A-4B, in various aspects the disclosure proposes a modular mask system 1 configured for cosmetic analysis and treatment, the modular mask system 1 comprising: a wearable modular mask 2, comprising: a front portion attached to a rear portion which includes a grid system 11 configured for cosmetic analysis, cosmetic treatment, or both; a template 3 configured to accept and guide a printer device (e.g., 100 of Figures 7A-8B) for the application of a cosmetic style to a portion of the individual's skin which is adjacent to the template 3; and an attachment site configured to accept and position a therapy device (e.g., 100 and / or 900 of Figures 9-12) for the application of a cosmetic treatment to a portion of the individual's skin which is adjacent to the attachment site.

[0044] In embodiments, the modular mask system 1 further includes control circuitry configured to control one or more cosmetic analyses and / or treatments. The control circuitry may include dedicated hardware circuitry, processor circuitry (for example, circuitry including machine-readable non-transient storage media storing instructions which, when executed by a processor, cause or configure the processor to perform all or part of a process or operation to control one or more cosmetic analyses and / or treatments; for example, including software, firmware, or the like).In some embodiments, the modular mask system 1 does not include control circuitry, but substantially includes a portable modular mask 2, as a passive physical platform, which contains one or more modular devices with their own control circuitry, as described herein.

[0045] In some embodiments, the modular mask system 1 further comprises a computing device including circuitry configured to interact with the control circuitry for the coordination, observation, or management of cosmetic analysis and processing by the computing device. In non-limiting examples, the computing device includes a smartphone, a A tablet, laptop, desktop computer, smartwatch, portable computing device, or any combination thereof. In some embodiments, the modular mask system 1 includes circuitry configured for cosmetic analysis of a portion of the individual's skin based on a skin feature. In some embodiments, the modular mask system includes circuitry configured to interact with a computing device that includes circuitry configured for cosmetic analysis of a portion of the individual's skin based on a skin feature.

[0046] In embodiments, the modular mask system 1 can be configured to generate, accept, manage, and / or modify one or more user profiles, which may be specific to an individual. The user profile may allow the system to configure itself for a particular set of one or more diagnoses and / or treatments specific to the individual. The user profile may include information such as skin type or color, locations of permanent scars, preferred or previously used diagnoses and treatments, and similar information.

[0047] A grid system 11, positioned on a rear portion of the wearable mask, may be composed of one or more structures configured for one or more diagnostics, therapies, or treatments, as described herein. In embodiments, the grid system 11 is configured for optical characterization of a portion of the individual's skin (for example, through one or more waveguides configured to capture light from a portion of the individual's skin), electrical characterization of a portion of the individual's skin (for example, through one or more current capacitance or resistance measurements for the detection of scars, moisture levels, or the like, using one or two or more electrical contact pins for capacitance measurements), light therapy (for example,through light-emitting diodes (LEDs) that transmit light through a plurality of waveguides arranged like a grid), microcurrent therapy (e.g., through a microcurrent therapy device), radio frequency (RF) heating therapy (e.g., through an RF heating therapy device), cold plasma therapy (e.g., through a cold plasma therapy device), acoustic energy therapy (e.g., via an acoustic energy therapy device), or any combination thereof.

[0048] In various embodiments, a modular mask system is configured for functional interaction between the mask 2 or another element of the system and a smart device 17, such as a smartphone, as shown in a non-limiting example in [Fig. 6]. A mask system 1 may include various fasteners of device (16a, 16b, 16c, 16d, 16e) configured for at least one light therapy, microcurrent therapy, radio frequency (RF) electric current heating therapy, cold plasma therapy, acoustic energy therapy, or any combination thereof, according to aspects of disclosure. In some embodiments, the modular mask system further includes an opening configured to accept at least a portion of a smartphone lens for smartphone-facilitated imaging of at least a portion of the individual's face with placement of the wearable modular mask on it via smartphone camera circuitry. PORTABLE MODULAR MASKS

[0049] In various aspects, the disclosure proposes wearable modular masks, configured as form factors that are comfortable when worn on the head and functional for diagnostic and cosmetic treatments as described herein. The wearable modular mask can be considered a modular platform with which several different diagnostic and / or cosmetic treatments can be combined and operated together or individually. Wearable modular masks can generally be shaped or configured to fit and / or cover at least a portion of an individual's face and / or head, for example, the scalp, the eye and / or forehead area, the nose and / or cheek area, the mouth and / or chin area, and the like, or any combination thereof.

[0050] One or more devices (e.g., printer devices, therapy devices, and the like) may be modular and removably attachable to an attachment point on the modular mask system for use in various aspects of disclosure. In some embodiments, an attachment point is positioned on a cheek portion of the wearable modular mask. For example, a therapy device may be attached to the wearable modular mask by means of a snap-fit ​​connection with 5a and / or 5b of the wearable modular mask shown in any of Figures 1A-4B.

[0051] By way of another non-limiting example, a printer device may be attached to a template 3 of the mask. The template 3 may include a guide rail that allows the printer device to move from left to right and right to left along the guide rail, for example, substantially parallel to the shape of the template 3, so that the printer device can consistently apply a cosmetic style to the subject's face or eyebrows. Since the printer device moves along the template 3, which maintains a constant vertical position of the printer device, the printer device exhibits little or no deviation from a substantially constant horizontal movement. The printer may require little or no corrections in nozzle placement for accurate and precise application of the cosmetic style.

[0052] In embodiments, a wearable modular mask includes a lower detachment point (e.g., 4 in Figures IA, IB, 3A and 3B), at which an eye portion (e.g., 9 in Figures IA, IB, 3A and 3B) of the wearable modular mask is detachable from a mouth portion (e.g., 10 in Figures IA, IB, 3A and 3B) of the wearable modular mask, as shown by way of non-limiting example in Figures 2A, 2B, 4A and 4B. In this way, a user can use all or part of the mask for one or more diagnostic and / or skin care treatments. In some embodiments, the modular mask system further includes a scalp portion (e.g., 13 of Figures 3A, 3B, 4A and 4B) of the wearable modular mask, wherein a rear portion of the scalp portion 13 includes a grid system 11 configured for cosmetic analysis, cosmetic treatment, or both.In some embodiments, the wearable modular mask includes a top detachment point at which the scalp portion of the wearable modular mask is detachable from an eye portion of the wearable modular mask, as shown by non-limiting examples in Figures 4A and 4B. PRINTER DEVICES

[0053] In embodiments, a modular mask system further includes a printer device, for example, all or one or more portions of a printer device as described in US patent application No. 18 / 345,339. In embodiments, the printer device is configured for precise application of makeup to a portion of the individual's eyebrow.

[0054] Figures 7A-8B show several views of an example of a printer device for applying a cosmetic style to a portion of an individual's skin. Printer devices, systems, and methods can be implemented for autonomous, semi-autonomous, and assisted manual application of a cosmetic style to a portion of an individual's skin, for example, by attaching a printer device to a template (as described herein) so that the printer device travels along the template to reliably apply a cosmetic style to an individual. The disclosed approaches allow the individual to correctly apply the composition in real time for more precise placement of the cosmetic style on the skin area.Printing devices are useful alone or in combination with smart devices, such as smartphones, for planning, selecting, and implementing cosmetic styles from a plurality of cosmetic styles.

[0055] As shown in [Fig. 7A] and [Fig. 7B], a printer device 100 includes a printer applicator 112, a position sensor and a reservoir for compositions intended for cosmetic styling. A display 140 of the printer device 100, if included in an embodiment, can represent the skin portion as a plurality of guide segments, and the printer applicator as a visual indicator relative to the plurality of guide segments, based on the position sensor. The visual indicator representation responds to changes in the position of the printer applicator relative to the skin portion to visually guide the individual to accurately apply the cosmetic style, and a feedback device or component alerts the individual if the application of the cosmetic style deviates or begins to deviate from the skin portion to allow the individual to correct the application.A user can use these or other elements to align the printer device 100 with the user's eyebrow position, so that attachment to the wearable modular mask template and its routing along the printer device 100 template allows for consistent application of cosmetic styles.

[0056] A printer device 100 is configured for applying a cosmetic style to a portion of an individual's skin and includes a printer 110, a position sensor, a display 140, and circuitry for performing all or part of an operation or process of disclosure. The printer 110 includes a printer applicator 112 functionally connected to a reservoir (145 of [Fig. 2A]) containing dye, and the position sensor is configured to detect the position of the printer applicator 112 relative to the skin portion. The display 140 can be configured to represent the skin portion as a plurality of guide segments and to represent the position of the printer applicator as a visual indicator (e.g., an arrow, a circle, a square, a triangle, and the like) relative to the plurality of guide segments.A position of the visual indicator as represented by the display 140 corresponds to a change in position of the printer applicator 112 relative to the skin area, resulting from the position sensor. The position data generated during a cosmetic style application can be evaluated as part of a quality control process, for example.

[0057] A circuit of the printer device 100, which includes, but is not limited to, a processor, a microprocessor, processor circuitry, and / or dedicated hardware circuitry, connects the printer 110, the position sensor, and the display 140 in a usable manner. The circuits are configured to instruct the printer 110 to print the cosmetic style by transferring the dye from the reservoir through the printer applicator 112 to the skin area, to calculate the position of the printer applicator 112 relative to the skin area using the position sensor, and to calculate a representation of the indicator. visual with respect to a guide segment of the plurality of guide segments based on the position of the printer applicator with respect to the skin part, and transmit to the display 140 for the representation of the visual indicator with respect to the plurality of guide segments by the display 140. In embodiments, the circuitry of the printer device 100 is configurable with a processor and processor-executable instructions stored on a machine-readable non-transient medium of the printer device 100, by way of non-limiting example, but other approaches to configuring the circuitry of the printer device 100 may be implemented in embodiments.

[0058] As shown in Figures 7A and 7B, in some embodiments, the printer device 100 includes a housing 105 and a handle 135. The printer device 100 is shown with a cylindrical housing 105 and a cylindrical handle 135, but can be implemented in any number of shapes and form factors. In some embodiments, the printer device 100 does not have a handle 135 as shown. In some embodiments, the printer device 100 includes internal circuitry, including a processor, a power source, such as a battery, and the like, for the electronic operation of the printer device 100.

[0059] In some embodiments, the printer device 100 includes a processor for executing instructions stored on a non-transient, computer-readable medium, enabling the processor to perform all or part of a disclosure method or process. In some embodiments, the processor is configured to receive a makeup image file, detect the position and curvature of a portion of an individual's skin based on the position sensor, and a printer device 110 to print a cosmetic style based on the makeup image file at a location on the skin portion. In some embodiments, the location is determined by a cosmetic style. For example, a lipstick cosmetic style can be printed on the individual's lips, eyebrow makeup can be printed on the individual's eyebrow, and so on.

[0060] In some embodiments, the printer device 100 is powered by a wired connection, for example, a wired electrical connection to an AC power source; however, in other embodiments, the printer device 100 is powered independently, in particular by a battery or a capacitor. In some embodiments, the printer device 100 includes a charging port configured to receive power from a power source to recharge a battery or capacitor of the printer device 100.

[0061] In some embodiments, the housing 105 houses the printer 110. In some embodiments, the printer 110 is positioned on a first side of the printer device 100, and display 140 is positioned on a second side of the printer device 100, as shown in Figures 7A and 7B. In some embodiments, the printer 110 includes a printer applicator 112 and one or more spacers 114A and 114B.

[0062] In some embodiments, the printer applicator 112 is configured to allow the printer 110, as shown in [Fig. 8B], to print a cosmetic style onto a surface. In some embodiments, the printer applicator 112 is rectangular, square, circular, organically shaped, or similar. In some embodiments, the printer applicator 112 is in the middle of a front side of the housing 105. In some embodiments, the printer applicator 112 is between the spacers 114A and 114B.

[0063] Although two spacers 114A and 114B are illustrated, it should be understood that any number and any configuration of spacers 114A, 114B can be positioned on the printer 110. In some embodiments, the spacers 114A, 114B are rounded polygons, as shown in [Fig. 7A], but it should be understood that the spacers 114A, 114B can be implemented in any number of shapes, including spherical, rectangular, and organic. In some embodiments, the spacers 114A, 114B are configured to make contact with a surface while the printer device 100 passes over it, so that an optimal distance between the printer 110 (or the printer applicator 112) and the surface is maintained. In some embodiments, the spacers 114A, 114B have a thickness that allows the printer applicator 112 to be in contact with a curved surface.In some embodiments, spacers 114A and 114B are configured to roll. In some embodiments, spacers 114A and 114B include at least one position sensor, as described herein. In some embodiments, in addition to maintaining a distance between the printer applicator 112 and the surface, spacers 114A and 114B are configured to roll over the surface when the printer device 110 prints the cosmetic style onto the surface.

[0064] In some embodiments, the printer device 100 includes a position sensor functionally coupled to the printer 110, as shown in [Fig. 8A]. In some embodiments, the position sensor is housed inside the housing 105, but in others, the position sensor is located on the front side of the printer device 100 with the printer applicator 112. In some embodiments, the position sensor is positioned inside one or both of the spacers 114A, 114B. In some embodiments, the printer device 100 further includes a camera, as shown in [Fig. 8A]. In some embodiments, the camera is configured to capture a plurality of images when the printer 110 moves over a part of the skin, such as a line of An individual's face. In some embodiments, the facial feature may be an eyebrow, a nose, an eye, a wrinkle, acne, or something similar.

[0065] In some embodiments, the printer 110 is a printer with a rotating, adjustable body. In some embodiments, the printer 110 is configured to articulate in order to scan a surface more precisely, such as a body, skin, or hair. In such embodiments, the position sensor 115 may be a sensor wheel as described herein. During operation, the position sensor 115 makes contact with the surface and rolls while the printer 110 scans the surface. In such embodiments, the printer device 110 is capable of taking into account the curvature of the surface, which may be a portion of a human body. In some embodiments, the printer 110 is adjustable to meet the needs of different body types and printing environments. In some embodiments, the printer 110 has an adjustable printer applicator 112.In some embodiments, the spacers 114A, 114B are movable or adjustable to change the size of the printer applicator 112. In some embodiments, the printer applicator 112 is concave or convex for better contact with the surface. In some embodiments, the printer 110 is configured to be articulated to improve contact with the surface. In some embodiments, the printer 110 is coupled to the printer device 100 with a flexible coupling, as shown in [Fig. 8B]. In some embodiments, the flexible coupling is a pivot, hinge, or joint. In some embodiments, the flexible coupling allows the printer 110 to be articulated. In some embodiments, this allows for more precise scanning of a surface. In some embodiments, it also allows the printer 110 to determine the curvature of a surface.

[0066] In some embodiments, the printer device 100 includes a display 140, configured for use as a user interface. Although the display 140 is shown on the back of the printer device 100, in some embodiments, the display 140 is a separate component, such as a smartphone or tablet. In some embodiments, the display 140 is round, but in other embodiments, it can be implemented in any shape, such as rectangular or oblong. In some embodiments, the display 140 includes one or more actuators, such as buttons or keys. In some embodiments, the display 140 includes a capacitive touch button. In some embodiments, the display 140 is a touchscreen. In some embodiments, the display includes one or more output modules configured to provide an alert, such as feedback, to the user. In some embodiments, the alert is a sound, vibration, or similar. In some embodiments, the alert includes an indication of how to move or in which direction to move the printer device 100 during use.

[0067] Figure 8A shows an exploded upper view, and Figure 8B shows an exploded lower view of the example printer device. In some embodiments, the printer device 100 includes an internal component 150, a printer 110, and a position sensor 115. In some embodiments, the printer device 100 includes a reservoir 145 and a processor 125. In some embodiments, the internal component 150 is configured to hold the printer 110 in place within the housing 105. In some embodiments, the internal component 150 is structurally coupled to the printer 110 and the reservoir 145.

[0068] In some embodiments, the printer 110 includes the position sensor 115 and one or more cameras 120A, 120B. In some embodiments, the cameras 120A, 120B are located on the printer 110, but in others, the cameras 120A, 120B are located on the housing 105. In some embodiments, when the printer 110 moves over a surface, such as an individual's face, the cameras 120A, 120B capture a plurality of images of the surface. In some embodiments, the cameras 120A, 120B capture a plurality of images of a facial feature when the printer device 100 moves over the facial feature. In some embodiments, the printer device 100 includes two cameras 120A and 120B. In embodiments such as those illustrated in [Fig.8B], a first camera 120A is located at the level of a first portion of the printer device 100, and a second camera 120B is located at the level of a second portion of the printer device 100, for example, opposite the first portion.

[0069] In some embodiments, as shown in [Fig. 8B], the printer device 100 comprises one or more light sources 130A, 130B. In some embodiments, the light sources 130A, 130B are LEDs. Although two light sources 130A, 130B are shown, any number of light sources can be implemented on the printer device 100, according to some embodiments. In some embodiments, the light sources 130A, 130B are positioned on the printer 110, but in other embodiments, the light sources 130A, 130B are positioned on the front side of the printer device 100.

[0070] In some embodiments, the printer 110 includes one or more position sensors 115. Although only one position sensor 115 is shown in [Fig. 8A], it should be understood that any number of position sensors 115 can be implemented. In some embodiments, at least one position sensor 115 is a rolling position sensor 115, such as a sensor wheel. In such embodiments, the position sensor 115 is configured to roll along the line of face when the printer 110 is moved along the facial feature. In this way, the position sensor 115 detects the position of the facial feature as the printer device 100 moves along it. In some embodiments, the position sensor 115 is further configured to detect the curvature of the facial feature or the user's face, i.e., the portion of the individual's skin.

[0071] In some embodiments, the printer device 100 includes a processor 125. In some embodiments, the processor 125 is coupled in a usable and / or communicative manner to the printer 110, the position sensor 115, and the camera 120. The processor 125 is configurable to receive a makeup image file, detect the position and curvature of the skin portion based on the position sensor, and direct the printer to print the cosmetic style based on the makeup file at a location. In some embodiments, the processor 125 is further configured to detect the illumination of the facial feature and instruct one or more light sources 130A, 130B to illuminate the facial feature. Although only one processor 125 is illustrated, it should be understood that any number of processors can be implemented in the printer device 100.

[0072] In some embodiments, the printer device 100 includes a reservoir 145. In some embodiments, the reservoir 145 is configured to hold one or more cosmetic inks or dyes, or other compositions for cosmetic styling. In some embodiments, the reservoir contains any number of cosmetic inks or dyes necessary to print the cosmetic style. In some embodiments, the reservoir 145 includes one or more cartridges, so that the reservoir 145 can hold any number of colors, compositions, finishes, or formulations of cosmetic inks or dyes.

[0073] In some embodiments, the processor 125 is further communicatively coupled to the reservoir 145 and the printer 110. In some embodiments, the processor 125 instructs the reservoir 145 and the printer 110 to produce a cosmetic style, such as a temporary tattoo, or makeup printed in the form of a facial feature. In some embodiments, the cosmetic style is selected from an eyebrow, eyeshadow, concealer, primer, foundation, blush, lip pencil, lipstick, bronzer, eyeliner, freckle pattern, facial hair, a hair or hair creation, such as facial hair or a hairline creation, or a complexion highlighter.

[0074] In some embodiments, the printer 110 is coupled to the printer device 100 with a flexible coupling 160. In some embodiments, the flexible coupling 160 is a pivot, a hinge, or a joint. In some embodiments In some embodiments, the flexible coupling 160 allows the printer 110 to be articulated. In some embodiments, this enables more precise scanning or printing of the surface. In others, it also allows the printer 110 to determine a surface curvature. THERAPY DEVICES

[0075] In some embodiments, the modular mask system further includes a therapy device, for example all or part of a therapy device as described in US patent application No. 18 / 756,759.

[0076] Figures 9 to 12 show views of an example applicator capsule and an example capsule and formula system, according to aspects of disclosure.

[0077] Iontophoresis is a non-invasive technique in which a physiologically acceptable amount of electric current (e.g., up to about 0.5 mA / cm² or typically 10 V or less) is used to facilitate the transdermal delivery of charged and / or neutral molecules. Iontophoresis does not tend to disrupt the skin barrier by promoting transdermal flow and acts directly on one or more compounds in a composition applied to the skin to deliver the compound into deeper layers of the skin. Electroporation applies a higher voltage pulse (typically about 100 V) for a very short duration (microseconds to milliseconds) to permeabilize the skin.

[0078] These techniques could potentially enable drug delivery through the skin and extend the scope of transdermal delivery to include not only small molecules, but also large molecules, such as protein drugs used in the biotechnology industry. However, the potential of these techniques has not been fully realized because the skin maintains a barrier that limits or prevents molecules from crossing it. Furthermore, iontophoresis and electrophoresis systems are typically configured for use with distinct classes of molecules delivered with different electrical currents or programs.A therapeutic composition that includes one or more biologically active molecules belonging to distinct classes may involve both iontophoresis and electrophoresis systems, which is inconvenient for the user or clinician and may lead to lower adherence to a treatment plan or other health complications due to inadequate treatment.

[0079] Accordingly, the portable modular mask system for disclosure can be implemented with intradermal and transdermal therapeutic delivery systems that are configured for iontophoresis and electrophoresis, which can more efficiently deliver a wide range of molecule types to and through the skin, and which are configured to heat compositions during use to relax the skin layers and widen the spaces between skin cells for a more efficient delivery of compounds in these. This disclosure addresses these and other long-unmet needs in art.

[0080] As shown in Figures 9-11, an example of an applicator capsule 100 includes a rolling ball 110, positioned within a rolling ball orifice 111, which makes rolling contact with the skin of a subject and rolls over the skin when a contact face 120 is placed adjacent to the skin during use. In the embodiment shown, the applicator capsule 100 includes a plurality of electrodes, including electrodes 130a, 130b, 130c, and 130d, configured for transmitting an electrical current through the portion of the subject's skin during use. Although four electrodes are included in the example embodiment, other quantities of electrodes may be implemented in other embodiments without departing from the scope and spirit of the disclosure.Examples of alternative quantities of electrodes include, but are not limited to, one electrode, two electrodes, three electrodes, five electrodes, six electrodes, seven electrodes, eight electrodes, nine electrodes, ten electrodes, or more.

[0081] In the illustrated embodiment, the applicator capsule 100 includes an insert 140 configured to be inserted into a body of the system for attaching the applicator capsule 100 to the body. The illustrated insert 140 includes an adapter 141 equipped with locking grooves 142a and 142b, which can slidably and reversibly lock onto the body when the applicator capsule 100 is attached to it. An electrode contact 150 is functionally connected to electrodes 130a, 130b, 130c, and 130d, via one or more electrical connections, for delivering electrical current from a power source through the electrode contact 150 to electrodes 130a, 130b, 130c, and 130d.Although the insert 140 shown includes a substantially spherical cross-sectional shape with a flat portion for the adapter 141, other cross-sectional shapes may be implemented without departing from the scope and spirit of the disclosure, it being understood that the insert 140 should be able to be secured to the body of the system, and the body may optionally include a cavity of corresponding shape to receive the insert 140 therein.

[0082] In the embodiment of [Fig. 10], an interior 162 of the applicator capsule 100 is fluidly connected to an interior of the system body by means of an orifice 161a in an external portion of the applicator capsule 100 and an orifice 161b in an internal portion of the applicator capsule 100. In the embodiment shown, the interior 162 of the applicator capsule 100 occupies a substantial or major portion of the volume of the applicator capsule 100; however, in other embodiments, the interior 162 may occupy a smaller or minor portion of the volume of the applicator capsule 100. without departing from the scope and spirit of the disclosure. The insert 140 may include an interface, such as an adapter 160, which interfaces with a correspondingly shaped interface within the system body to form a fluidic seal to prevent leakage of a composition from it. When using the example system shown, the composition flows from inside the system body into the inside 162 of the applicator capsule 100, and at least partially fills the inside 162 until it reaches the rollerball orifice 111. The composition flows through the rollerball orifice 111 and out of the applicator capsule 100, where it comes into contact with the rollerball 110 and the subject's skin portion during application.

[0083] In the embodiment of [Fig. 11], an interior 162 of the applicator capsule 100 is not fluidically connected to an interior of the system body, and does not include orifices as shown in [Fig. 10] (i.e., orifices 161a, 161b). Instead, in the embodiment of [Fig. 11], the interior 162 may include a composition therein, and the adapter 160 may be coupled, on a lower portion thereof, to a piston. With an upward movement of the piston, the adapter 160 can slide upward within the interior 162 and compress the composition therein, so that the composition is expelled through the rollerball orifice 11 and out of the applicator capsule 100, where it comes into contact with the rollerball 110 and the subject's skin during application. In some embodiments, after use, the applicator capsule 100 can be removed and cleaned for reuse.

[0084] As shown in [Fig. 12], an example of a system 900 for applying a composition to a portion of a subject's skin comprises an applicator capsule 100, including a plurality of electrodes (130a, 130b, 130c, 130d) configured for transmitting an electric current through the portion of the subject's skin, and a body 200, configured for reversibly attaching the applicator capsule 100 to it, and a reversibly formula cartridge 112 which includes a rolling ball 110 configured for rolling contact with the portion of the subject's skin. The formula cartridge 112 can be attached to the applicator capsule 100 and is configured to contain and release the composition, from a reservoir within the formula cartridge 112, on the basis of at least one operation of a non-contact piston of the body 200 for the delivery of the composition from the reservoir of the formula cartridge 112 to the portion of skin.

[0085] As such, the rolling ball 110 can be an element of a formula cartridge 112, as shown by way of non-limiting example in [Fig. 12]. An example of a formula cartridge 112 of system 900, according to embodiments, comprises inside a composition for application to the subject's skin, and can be inserted into an applicator capsule 100 and thus functionally connected to a body 200 of the system 900. In the embodiment shown, a piston can extend through an orifice 207 of the body 200 and the interior of the applicator capsule 100, and can mechanically expel the formula from the formula cartridge 112 with a movement of the piston. A power supply to the body 200 can be functionally connected to the applicator capsule 100 by means of an electrical connection 208, which can be configured to connect electrically to a corresponding electrical connection on the applicator capsule 100.In the embodiment shown, a formula cartridge microchip 113 is included and configured to allow identification of the composition within the formula cartridge and / or one or more of its components, for the selection of an application program by electroporation and / or iontophoresis of the composition, as described herein. Since the formula cartridge 112 can be easily removed from the device, it can be exchanged for alternative formula cartridges 112, for example, alternative compositions. In the embodiment shown, the device body 200 may not include a reservoir as in other embodiments, since the composition can be supplied by the formula cartridge 112, as shown.

[0086] An example of an application system for applying a composition to a portion of a subject's skin may include a form factor that includes a body with a body surface that is shaped and / or configured, for example, ergonomically shaped, to be grasped by a user for operating the system and / or may be compact and configured to snap into or connect with mask attachment sites. In embodiments, an applicator capsule may be attached to the body by means of an insert attachment. The insert attachment may include a snap-on attachment, for example, such that the adapter may be inserted into the body and secured in place by the snap-on attachment of the insert attachment, or alternatively, by means of locking grooves that are locked in place. Other attachment mechanisms may be implemented for insert attachment without departing from the scope and spirit of the disclosure.

[0087] In embodiments, the body 200 includes a power source (for example, a cell or battery) functionally connected to an actuator by means of one or more electrical couplings. The actuator can mechanically actuate a piston of the system to convey a portion of a composition from a reservoir of the system, from the reservoir through the body and to the applicator capsule. The power source can be electrically coupled to the electrodes (130a, 130b, 130c, 130d) for the transmission of electrical current to the electrodes based on a system program, for example.

[0088] In embodiments, the system may include a reservoir that can be attached to the body by means of a reservoir fastener. The reservoir may be reversibly attached to the body and may be secured, for example, by means of a snap fastener or other fastening mechanism, and removed by reversing the snap fastener or other fastening mechanism. The reservoir is configured to contain the composition inside and release the composition from it, such that the composition flows through an interior of the body into an interior of the applicator capsule based on the operation of a piston or a piston without contact with the body.With the movement of the composition through the inside of the body and the inside of the applicator capsule, and out of the rolling ball orifice, the composition can effectively flow from the reservoir through the body of the system and out of the applicator capsule, where it comes into contact with the skin and is ready to be applied by rolling onto the skin and electrically transmitted to and / or through one or more layers of the skin, as described herein.

[0089] In some embodiments, the system can be controlled, at least in part, by a user via control circuitry, which may include a start button and / or an eject button functionally connected to the control circuitry by means of one or more electronic connections. In the embodiment shown, the start button can be activated by a user to turn on the system or to activate a system function, such as a contactless piston operation to expel the composition, or a cleaning solution or liquid, from the system. In some embodiments, the eject button can be activated by a user to eject the tank from the system body, for example, for tank replacement and / or cleaning or maintenance of the system or a component thereof.In some embodiments, a status indicator is included and is functionally connected to the control circuitry, or other system circuitry, to indicate the system status to the user. The status indicator may indicate the state of one or more system components, such as the charge level of a rechargeable system battery, the tank fill level, the need to clean the system or a component thereof, and the like.

[0090] According to exemplary embodiments, the system includes the body and may include, in various aspects, an applicator capsule 100, a rolling ball configured for rolling contact with the subject's skin portion, and a plurality of electrodes. The system may include one or more electrodes configured or configurable for radiofrequency (RF) heating or ultrasonic electrical transmission, as well as one or more electrodes configured or configurable for electrical transmission by electrophoresis and / or iontophoresis. as in the embodiment shown. The electrodes can be functionally connected to system control circuitry and to a system power source, such as a rechargeable battery, for generating one or more current patterns. These current patterns can be at least part of a program for delivering one or more molecules from the reservoir composition to the subject's skin portion. The program can be selected by the control circuitry based, at least in part, on the composition (or a characteristic identifying it), as described herein.

[0091] In some embodiments, a formula cartridge may include a microchip that corresponds to one or more compounds of a composition within the formula cartridge. The system may select, based on a composition identification characteristic obtainable by the system from the microchip, a program for administering one or more therapeutic electrical currents. The composition characteristics may include one or more molecular weights of one or more compounds, one or more ionic states of one or more compounds at a given pH and ionic strength of the composition, or similar characteristics. For example, larger molecules in a composition may require the application of a stronger current to efficiently transport the molecules to and through one or more layers of the skin.In some embodiments, a user can control one or more operating modes, or programs, of the system to increase or decrease the current according to the user's preference.

[0092] In some embodiments, one or more components of the composition may be electrically resistive to provide a degree of electrical resistance to the composition as a whole; in this way, the electric current from an RF heating current or an ultrasonic electrical transmission encounters resistance with these one or more components, generating heat within the composition, which in turn warms the skin. In some embodiments, the system may create an alternating electric field with an oscillating frequency, and the resulting current may be introduced into the skin via one or more electrodes. In some embodiments, the current may heat the skin directly due to electrical resistance within the skin.In some embodiments, the current can heat the skin indirectly, by heating one or more components of the composition, and directly, in combination, for enhanced skin heating. In some embodiments, a frequency range of 300 kilohertz (kHz) to 1 megahertz (MHz) can be used. In some implementation examples, a frequency of 450 kHz can be used.

[0093] Accordingly, in some aspects, the disclosure proposes an "intelligent" system comprising circuitry configured to implement all or part of a process, including, but not necessarily limited to, controlling the expulsion of the composition from the system, monitoring a level of the composition inside the tank, monitoring a charge level of the power source, and the like. In some embodiments, the circuitry of a device is configurable with a processor and processor-executable instructions stored on a non-transient machine-readable medium of the device. In some embodiments, a device includes a software application configured to implement all or part of one or more of the disclosure's methods or processes, in any order or combination. However, in some embodiments, a device includes dedicated hardware circuitry.An additional circuitry configuration of the device may include wireless communication or networking circuitry, for example, circuitry configured for a wireless connection, such as a Bluetooth® connection, a Bluetooth® Low Energy (BLE) connection, and / or a Wi-Fi® connection, and / or a wired connection. The networking circuitry, in combination with other circuitry of the computing device, may be used to request, retrieve, and / or receive data from a remote computing device or server, for example. In some embodiments, the device may be operated using a computing device, such as a smartphone or personal computing device, which may be operated by a user via a graphical user interface, as known in Art.In some embodiments, the circuitry may include an operational connection of one or more sensors with the processor, or other circuitry, to perform logical operations and / or processes based on data received from one or more sensors, for example.

[0094] An example of a system includes an applicator capsule that can be functionally connected to the body by means of one or more functional connections, for example, physical, fluid, and electronic connections, for electronic and fluidic communication between the capsule and the device body. The applicator capsule includes one or more electrodes on it that are functionally connected to the system's control circuitry for the delivery of a microcurrent, for example, for the transmission of an electroporation current, an iontophoresis current, an RF heating current, or any combination thereof, to the subject's skin area.

[0095] In some embodiments, the system includes a computer or computer circuitry, which may include, control and / or direct control circuitry, or other system circuitry, to perform one or more system operations. Computer circuitry may include hardware circuitry, processor circuitry, or both, configured to perform logical operations, such as turning an electromagnet on and off for non-contact piston movement and expulsion of the system composition, selecting and executing one or more programs for microcurrent delivery (e.g., electroporation, iontophoresis and / or RF heating current), monitoring a power source's state of charge, monitoring the percentage of composition used in the tank, and the like.Computer circuitry may include a non-transient, computer-readable medium on which instructions are stored that, when executed by one or more processors, configure one or more processors to implement all or part of a disclosure process or operation, in whole or in part, the steps being in any order. The system may be configured to accept user input, which may include an enable or disable signal (e.g., using a power button), a status polling signal (e.g., using a power button or other control element), or the like.

[0096] The computer circuitry controls, coordinates, directs, or otherwise enables the transmission of microcurrents as part of the execution of skin composition delivery programs. In some embodiments, the computer circuitry enables the transmission of one or more pulses for the delivery of a current that is a high voltage and / or a high frequency, by means of electroporation circuitry and / or microcurrent circuitry. The computer circuitry controls, coordinates, directs, or otherwise enables the transmission of RF heating current by means of ultrasonic transducer circuitry. An electrode can be configured and used for electrophoresis, iontophoresis, or both (sequentially and / or simultaneously), and the ultrasonic transducer circuitry can be configured and used for RF heating current transmission.

[0097] In embodiments, the computer circuitry can be configured to electronically control at least one operation of the non-contact piston. For example, the computer circuitry can, as part of the execution of at least one application program for a composition, deliver an electric current to an electromagnet of the system to activate the electromagnet and attract or repel the non-contact piston, which may be magnetic and / or functionally connected to a magnet, for the movement of the non-contact piston and the displacement of the composition within the body of the system.

[0098] In embodiments, the computer circuitry can be connected and functionally configured to receive a signal from a microchip in the reservoir that corresponds to one or more compounds of the composition in the reservoir. The control circuitry can thus identify the one or more compounds in the composition to be delivered to and / or through the skin, and can electronically control the transmission of the electric current, based on a program selected by the control circuitry, for the delivery of the one or more compounds to the portion of the subject's skin. For example, as part of a program selection in an example system, a capsule can be attached to the body of the device to deliver a microcurrent based on an identification of the composition or one of its components.The device's control circuitry can receive a signal from the microchip, via wired and / or wireless transmission, such as radio-frequency identification (RFID), which identifies one or more components of the formulation, or the formulation as a whole. The system can then select a microcurrent delivery program based on the identity of the identified components or the formulation as a whole. For example, if one or more large molecules are present in the formulation as active ingredients to be delivered to the skin, the system can select a program that includes electroporation of the large molecules. If one or more small molecules are present in the formulation as active ingredients to be delivered to the skin, the system can select a program that includes microcurrent delivery, such as iontophoresis.In some embodiments, a program that includes only electroporation (and not microcurrent) is selected. In some embodiments, a program that includes only microcurrent (and not electroporation) is selected. In some embodiments, a program that includes both electroporation and microcurrent is selected. In this way, in some embodiments, one or more components of the composition comprise a large molecule, a small molecule, or both, and the program configures the control circuitry for the transmission of electrical current based on the signal, for example, received from the microchip in the reservoir.

[0099] Accordingly, in some embodiments, iontophoresis delivers a large molecule of the composition, a small molecule of the composition, or both, through a dermal layer of the skin portion. In some embodiments, the electric current comprises a radiofrequency (RF) heating electric current. In some embodiments, the RF heating electric current creates one or more microchannels in a dermal layer of the portion of skin. In some embodiments, the RF heating electric current is transmitted at a frequency in the range of 100 kHz to 1 MHz.

[0100] In another aspect, the disclosure proposes a method for administering a composition to a portion of a subject's skin, the method comprising: receiving, with control circuitry of a system, a signal from a microchip in a reservoir of the system, wherein the reservoir contains at least a portion of the composition and the signal corresponds to one or more components of the composition in the reservoir; activating, with control circuitry of the system, an electromagnet of the system to move a non-contact piston of the system and move at least the portion of the composition from the reservoir through an interior of a body of the system to an interior of an applicator capsule of the system to expel at least the portion of the composition from one or more orifices of the applicator capsule; and transmitting, with control circuitry of the system, an electric current through the portion of the subject's skin,in which the transmission of the electrical current is based on a program selected by the control circuitry based at least in part on the signal. According to various examples, a method of using a disclosure application system to apply a composition to a portion of a subject's skin is considered. An applicator or reservoir filled with formula or composition is attached to the dispensing device, which includes the body and other system elements. The formula is identified by the system's control circuitry as it reads a contactless chip by receiving the signal, for example, with a contactless reader (e.g., an RFID reader). A magnetic field is generated to move the piston and displace the composition from the reservoir. The composition is dispensed from the system as the piston moves. One or more microcurrent treatments are implemented.and a formula can be applied with or without a rolling ball.

[0101] In embodiments, an electrical impedance may be delivered as at least part of an RF heating microcurrent, which may range from approximately 10 to 50 kOhms. In embodiments, electrical pulses may be delivered in short bursts, for example, a 1 ms burst every 100 ms (1% load). In embodiments, a 1% load, a 2% load, a 3% load, a 4% load, a 5% load, a 6% load, a 7% load, an 8% load, a 9% load, a 10% load, an 11% load, a 12% load, a 13% load 14%, a 15% charge, a 16% charge, a 17% charge 18%, a 19% charge, a 20% charge, a 21% charge of 22%, a charge of 23%, a charge of 24%, a charge of 25% or a charge A higher percentage load can be applied to an RF heating microcurrent. The percentage load can be calculated by dividing the electrical burst time by the total time and multiplying the result by 100%. As a person skilled in the art would understand, a higher intensity RF heating microcurrent can be applied at a lower percentage load to avoid skin overheating; similarly, a lower intensity RF heating microcurrent can be applied at a higher percentage load to ensure effective skin heating.

[0102] In some embodiments, electroporation is delivered before, during, and / or after iontophoresis and / or RF heating. In some embodiments, iontophoresis is delivered before, during, and / or after electroporation and / or RF heating. In some embodiments, RF heating is delivered before, during, and / or after electroporation and / or iontophoresis.

[0103] By way of example of a method, one or more pairs of electrodes of the system may operate in simultaneous mode, as follows:

[0104] RF heating activated for a 90% load;

[0105] RF heating off, duration during which electrophoresis and / or iontophoresis are applied.

[0106] By way of another example of a method, one or more pairs of electrodes of the system can be used in sequential mode, as follows:

[0107] RF heating activated for a 50% load;

[0108] RF warming off, duration during which the skin cools sufficiently to maintain the warming effect and the opening of the pores;

[0109] Electrophoresis and / or iontophoresis is applied.

[0110] An example of an applicator capsule may include an example of a piston assembly. A capsule may include a cap, a rolling ball, a mounting tip, a body, a piston, a stopper, a push rod, and an authentication chip. The example of the piston assembly shown, as well as other structures shown to allow movement of the composition inside the capsule, may be incorporated into various embodiments that include a rolling ball and electrodes, as described herein. In some embodiments, the cap may be disposed at a first end of the body and configured to attach to the body. For example, the cap may be screwed and tightened by twisting onto the body, which may also be screwed (as shown), or the cap may be tightened by snapping onto the body. The mounting tip may be disposed at the first end of the body.The cap, mounting tip, body, piston, and stopper can be made from a polymer material. Non-limiting examples of materials for the cap, mounting tip, body, piston, and stopper (separately) are listed below. (or assembly) may include a thermoplastic elastomer, polypropylene (PP), polyethylene terephthalate (PETG), acrylonitrile butadiene styrene (ABS), polycarbonate (PC), polyamide (Nylon), polystyrene (PS), low-density polyethylene (LDPE), high-density polyethylene (HDPE), or any combination thereof. For example, all parts may be made of PP. In another example, the cap may be made of PP, the mounting tip of PETG, the body of PP, the piston of LDPE, and the plug of PP.

[0111] The body may have a substantially cylindrical shape and may include a first opening at one end and a reservoir at a second end, wherein an internal diameter of the first opening is larger than an internal diameter of the reservoir. Both the first opening and the reservoir may be substantially annular. The first opening of the body may include a substantially straight stroke length having the internal diameter of the first opening. The first opening may narrow until it reaches the internal diameter of the reservoir. The reservoir may be substantially straight and connected to the conical portion extending from the first substantially straight stroke length. It may be appreciated that the cross-sectional shape of the body may be manufactured in any of a myriad of other shapes, for example, triangular, square, pentagonal, hexagonal, octagonal, or similar.

[0112] The first opening can be configured to contain the mounting tip. The mounting tip can include an external shape configured to fit by pushing into the first opening, wherein the shape of the mounting tip can follow the contour of the substantially straight stroke length and the conical portion extending from the substantially straight stroke length. Thus, the mounting tip can form a liquid-tight seal with the first end of the body. In some embodiments, the mounting tip can be manufactured as part of the body at the first end of the body. For example, the mounting tip and the body can be molded together as a single piece. The mounting tip can be configured to retain the rolling ball, wherein an internal shape of the mounting tip is substantially hemispherical.One end of the mounting fitting may include a ball bearing retainer. The ball bearing retainer may be an annular extrusion of material extending from the first end of the mounting fitting, which may taper slightly towards the inside of the fitting, so that the internal diameter of the retainer is narrower than the diameter of the ball bearing. The ball bearing can be installed in the mounting fitting by pushing it through the opening in the retainer. The roller ball retainer can deform elastically outward (i.e., the opening of the roller ball retainer widens and can thus be made of a deformable polymer) to accommodate the roller ball when it is pushed through, and then return to its original internal diameter. The roller ball can be made of glass, metal, or polymer, such as those described for the cap, mounting tip, body, piston, and plug.

[0113] The piston and the plug can be disposed at the second end of the body. The piston can have a shape substantially similar to a disc and can include an external diameter equal to, or marginally smaller than, the internal diameter of the reservoir, so that a liquid-tight seal can be formed between the piston and the inside of the reservoir. The plug can also have a shape substantially similar to a disc. The piston can be installed in the reservoir and the plug can be installed at the second end of the body, in which the plug prevents the piston from exiting. The plug can be adjusted by pushing, adjusting by snapping, tightening by twisting, or chemically fixed to the second end of the body. The plug can include a hole in the center, configured to allow the push rod to pass through it reversibly. In another embodiment, the plug can be manufactured as part of the body at the second end.For example, the cap and body can be molded together as a single piece. It can be appreciated that the piston and cap can be shaped according to the cross-sectional shape of the body, and the disc-like shape is just one example.

[0114] A first end of the push rod can be configured to abut against the piston. For example, the piston may include a molded indentation opening toward the second end of the body having a shape complementary to the first end of the push rod. A second end of the push rod (not shown) can be attached to a metering device (not shown) configured to move the push rod a predetermined distance. The metering device may be in the form of an applicator, and such an applicator would be configured to receive the capsule. The abutment of the first end of the push rod against the piston thus causes the piston to move toward the first end of the body (i.e., into the reservoir) by the same predetermined distance as the push rod.

[0115] The reservoir can be configured to contain a composition, for example, a solution. In some embodiments, the solution may be a cosmetic. In some embodiments, the composition may comprise one or more small molecules to be delivered to and / or through the skin, one or more large molecules to be delivered to and / or through the skin, or any combination thereof.

[0116] In embodiments, the composition may be a topical medicinal product, such as a serum, ointment, lotion, oil, essential oil, cream, gel, paste, foam, water-based mixture, and alcohol-based mixture (e.g., a tincture), or any combination thereof. The topical medicinal product may include active ingredients, such as a drug content, for treating skin conditions, and / or may include nutrients, for example, vitamins and minerals.

[0117] A capsule may include a mounting tip which may include a well. The well may be the volume between the rolling ball and the inside of the mounting tip. The well may be configured to receive a predetermined volume of solution from the reservoir. The mounting tip may include a solution regulator disposed at a second end of the mounting tip through which the predetermined volume of solution is transferred from the reservoir to the well. The solution regulator may be an orifice or a partially open orifice through which the solution flows to the well, and the solution regulator may be configured to measure the predetermined volume of solution passing through and prevent an undesired reverse flow of solution from the well to the reservoir.

[0118] In some embodiments, the solution regulator may be provided by a check valve. The solution regulator may be substantially open and configured to allow the attachment or insertion of the check valve. The check valve may be installed inside or proximal to the second end of the mounting fitting and held in place by a check valve bracket. The check valve and the check valve bracket may be installed in the tank through the second end of the body. For example, the check valve may be installed first and the check valve bracket subsequently, wherein the check valve bracket includes features that allow it to be snapped into complementary features of the tank.In another non-limiting example, the check valve can be coupled to the check valve support before both are installed in the tank. In yet another non-limiting example, the check valve and the check valve support can be chemically bonded to the tank, for example, by adhesive, epoxy, sealant, or any combination thereof. In some embodiments, the check valve and the check valve support can be manufactured as a single unit; that is, the check valve includes features that allow it to snap into the complementary features of the tank without requiring a separate check valve support. Non-limiting examples of materials for the check valve support include thermoplastic elastomer, PP, PETG, ABS, PC, Nylon, PS, LDPE, HDPE, and any combination thereof.

[0119] In some embodiments, the check valve may be a unidirectional valve allowing solution transfer in only one flow direction (or preventing solution transfer in said flow direction when a flow stoppage is desired). The check valve may be a deformable diaphragm held in position by tension, in which the tensioned position forms a liquid-tight seal. For example, the check valve may be made of LDPE or PETG. In response to a force applied to the deformable diaphragm from a single direction, the diaphragm may be deflected along the direction of the applied force. Upon release / cessation of the applied force, the tension on the diaphragm may return the diaphragm to its undeflected orientation. Thus, the check valve may be in one of two states.A first state can be closed and liquid-tight, in which the check valve does not allow the transfer of solution from the tank to the well. It can be understood by those skilled in the art that other one-way check valves can be used without departing from the scope and spirit of this disclosure, for example, a spring-loaded ball design. A second state of the check valve can be open, in which the check valve diaphragm is deflected, thus breaking the liquid-tight seal and allowing the transfer of solution through the check valve.

[0120] In some embodiments, the push rod can be moved translationally a predetermined distance. The push rod can simultaneously move the piston translationally a predetermined distance in the direction of the first end of the body. Since the solution in the reservoir may not be compressible, the force of the piston pushing on the solution can cause the check valve to move from its first state (closed) to its second state (open). The open check valve can then allow the predetermined volume of solution to be transferred from the reservoir to the well. The rolling ball can be spherical and include a first surface area in contact with the solution that has been transferred to the well. The rolling ball can include a second surface area exposed to the outside and configured to come into contact with the skin of a user.The rollerball can be configured to roll across the user's skin and transfer a predetermined volume of solution, such as topical medication, from the well to the user's skin. As the rollerball rotates across the user's skin and deposits the solution, the second portion of the surface rolls back into the well and is re-coated with more solution. Specifically, the mounting tip can be manufactured to include some clearance between the inside of the mounting tip and the rollerball to allow the rollerball to roll smoothly and facilitate re-coating without the inside of the mounting tip scraping away the solution coating as the rollerball rolls.

[0121] The predetermined translation distance of the push rod can be determined by calculating the required piston travel distance to move the predetermined volume of solution into the reservoir. The maximum predetermined volume of solution transferred from the reservoir can be determined by calculating the volume of solution the well is capable of holding. The predetermined volume of solution actually transferred from the reservoir to the well can be determined by the dosing device; for example, the user may be attempting to complete a recommended regimen for treating a skin condition. Thus, the user may require a specific dosage of topical medication for application to the user's skin, and the dosing device can be configured to transfer the predetermined volume of solution from the reservoir to the well at a predetermined frequency.For example, the dosing device can transfer 0.3 mL of solution daily during a 14-day treatment plan, where the device is configured to allow the user to apply the solution for a predefined duration, such as 3 minutes per day. An embedded chip in the dosing device can record user usage and piston position. When the piston position is determined to correspond to the 14th day of treatment, the dosing device can notify the user to replace the capsule. Upon confirmation that the user has removed the capsule, the dosing device can adjust and reset the piston position to a position corresponding to the start of the 14-day treatment plan. Furthermore, the dosing device can reset the embedded chip to resume recording user usage.

[0122] Advantageously, the integrated solution regulation feature, i.e., the check valve, can prevent the transfer of excess solution to the well once the piston stops and the force release (and tension on the check valve) closes the check valve. Therefore, this prevents the user from applying too much solution, which can be important when the solution is a topical medication containing a particular active ingredient, for example, a drug, which should not be overdosed.Furthermore, this can be facilitated by the dosing device in which the capsule is installed, in which the dosing device prevents the user from overdosing by only making the piston move via the push rod a predetermined number of times in a predetermined time period, for example once a day, and not more frequently than programmed regardless of user input (for example, the user requesting another dose from the dosing device).

[0123] In some embodiments, a therapy device is configured for cold plasma treatment, for example, as described in document WO 2020028329 AL. Consequently, a cosmetic treatment system and method The treatment of a region of a biological surface using cold atmospheric plasma is presented. In embodiments, a method for treating a region of a biological surface with cold plasma includes: the selection of a post-treatment formulation; and the application of the post-treatment formulation to the region pre-treated by the cold plasma.

[0124] Wearable cosmetic devices incorporating cold atmospheric plasma (also called "cold plasma" or "plasma"), as currently available, implement limited treatment modalities. Most focus solely on generating plasma near a specific area of ​​a person's skin as a treatment pathway for that area. Such an approach does not take advantage of the therapeutic benefits of multimodal treatment and does not create synergistic therapeutic results that surpass the effect of the individual treatment modalities alone. In embodiments of the present technology, a multimodal cold plasma device includes one or more auxiliary or supplementary mechanisms (vibration, heat, etc.) in addition to cold plasma generation.

[0125] A multimodal plasma device that takes advantage of the synergistic effects of the treatment will provide better results with a shorter treatment time and reduced power demand, compared to a monomodal plasma device. Furthermore, a multimodal device mitigates the potential risks of excessive exposure to potentially harmful species generated in the plasma, such as oxidizing species or reactive radicals, by improving the permeability of plasma-generated species, or by providing secondary treatment that does not rely on plasma-generated species for its efficacy.

[0126] Blemishes develop for several reasons, including harmful bacteria, clogged pores, irritation, moisture or oil imbalances, etc. Generally, blemishes progress from an early, easily treatable stage to a painful and difficult condition within a single day, often within hours of the first detection of a new blemish. While not related to theory, it is believed that exposure to cold atmospheric plasma and the species generated therein will effectively treat blemishes. It is further believed that prompt treatment at the site of the blemish, immediately after its detection, prevents the growth of unsightly blemishes that can leave permanent scars.

[0127] Cold plasma devices designed to treat large areas of skin, incorporating sufficient internal power sources for prolonged use, are too large and heavy to be easily transported regularly. Although well suited to a cosmetic routine that takes place at home, their size and weight make them less suitable for a quick response to an imperfection or An acne lesion in development that is discovered outside the home. It is believed that a small-area plasma device designed for the rapid treatment of individual blemishes, also known as "spot treatments," will effectively treat an imperfection in its early stages and will be portable and convenient.

[0128] Direct exposure of a biological surface region to cold atmospheric plasma can be supplemented by therapeutic regimens (also called "formulations" or "therapeutic formulations"). For example, plasma-generated species, such as ultraviolet photons or reactive oxygen species, can damage biological surfaces. Therefore, therapeutic formulations can be used to prevent or minimize damage to biological surfaces.

[0129] In some embodiments, a pre-treatment formulation protects the area against potentially harmful plasma-generated species. In another embodiment, a post-treatment formulation neutralizes plasma-generated acids that can damage the biological surface after treatment. In some embodiments, plasma-activated media provide effective therapy when applied to the area without direct plasma exposure. While not related to the theory, it is believed that cold atmospheric plasma produces reactive species and side reaction products that remain in liquid media after plasma exposure.

[0130] Although basic plasma therapy is expected to have a beneficial impact on biological systems, the risks of overexposure or unintentional harm are not negligible. Consequently, conventional plasma devices limit a consumer's ability to implement personalized therapy. These treatment risks can be mitigated by customizing the plasma for a specific desired therapeutic outcome. In some embodiments, the size of the target treatment area is selectable. In other embodiments, a chemical intermediate can modify the concentrations of potentially harmful species generated in the plasma. In practice, surface conditions and plasma parameters are coupled, where a variation in one induces changes in the other.A sudden change in surface moisture, for example, can affect the surface's electrical conductivity and lead to an increase in plasma intensity. Conversely, a sudden increase in plasma intensity can vaporize surface moisture, which in turn changes the plasma's properties. This variability and multiparameter coupling necessitate control of the plasma treatment device.

[0131] Complex interactions between plasma light emission, plasma-generated species and biological chemicals native to biological surfaces These factors further complicate cold plasma therapy. In some cases, plasma-generated species can acidify a biological surface, thereby exacerbating pre-existing conditions and negating any beneficial effects of plasma treatment. This could be achieved, for example, through light emission or exposure to plasma-generated species that stimulate wound healing or would otherwise denature harmful bacteria present on the biological surface. However, measuring the plasma treatment on a biological surface can allow for plasma modulation, making the treatment more effective and safer.

[0132] Uniformity and consistent application of cold plasma during treatment are desirable for several reasons. Non-limiting examples include delivering a predictable dose of plasma-generated species to the biological surface, providing a consistent treatment outcome despite variability in biological surface conditions, maintaining uniform exposure to cold plasma over a region of a biological surface, etc.

[0133] Cold plasma therapy devices

[0134] Non-thermal “cold” atmospheric plasma can interact with living tissues and cells during therapeutic treatment in several ways. Among the possible applications, cold atmospheric plasma can be used in biology and medicine for sterilization, disinfection, decontamination, and plasma wound healing.

[0135] Several commercially available devices are currently certified for medical treatment. These devices are not intended for home use by consumers. Rather, they are designed for use by experienced medical technicians trained in medical treatment techniques. One such device is Rhytec Portrait®, a plasma jet tool for topical dermatological treatments. This device features complex power supplies with tightly regulated parameters, using radiofrequency power sources. In addition, the Bovie J-Plasma®, the Canady Helios Cold Plasma, and the Hybrid Plasma™ Scalpel are all available for use as medical treatment devices.In Germany, the kINPen®, also a plasma jet device, and the PlasmaDerm®, a dielectric barrier discharge (DBD) device, are both certified medical devices that have been marketed in recent years. These devices are intended for the medical treatment of human tissue, either externally, as in the case of the PlasmaDerm®, or internally. Unlike medical plasma devices, cosmetic devices are designed for generally intuitive use by consumers, resulting in a cosmetic treatment. and a pleasant sensation, as opposed to a well-controlled and certifiable therapeutic effect.

[0136] A plasma generator can be implemented in accordance with the prior art. A cold plasma is formed by the disparate excitation of electrons in a plasma gas by electric fields, relative to the weaker excitation effect of the fields on the more massive nuclei of the plasma gas. The cold plasma forms between a live electrode and a ground electrode, also called a counter electrode, when the live electrode is powered relative to the ground electrode by a power source. The power source is an alternating current source or an amplitude-modulated direct current source. The cold plasma is a dielectric barrier discharge if the plasma generator includes a dielectric barrier placed against the live electrode. The cold plasma contains both high-temperature electrons, low-temperature ions, and neutral species.In conventional systems, the plasma gas comprises noble gases such as helium or argon, as well as gases containing oxygen and nitrogen to form reactive oxygen and nitrogen species (RONS). In some cases, such as with PlasmaDerm®, the plasma is formed directly in the air.

[0137] A dielectric barrier discharges during operation. The plasma forms in the form of multiple discrete filamentary discharges which individually form conductive bridges so that ions and electrons migrate between the electrodes.

[0138] For topical treatment, several forms of plasma are used. The first is gas jet plasma, which provides a jet of ions and reactive species that can be directed at a target over varying distances, generally greater than a few millimeters. The medical plasmas described in a previous paragraph typically include gas jet plasma. A second form is floating electrode dielectric barrier discharge (FE-DBD) devices, in which the target substrate (often the human body) acts as a floating mass electrode. The third form is a plasma DBD rod, where the dielectric barrier is placed against a floating mass, instead of the live electrode, and may take the form of a fluorescent tube. The fourth form is a coordinated plurality of dielectric barrier discharge sources.In such an arrangement, a number of atmospheric FE-DBD plasma sources are incorporated into a handheld or flexible device, which is then used to treat one or more anatomical regions.

[0139] A cold plasma system can be implemented. A skin treatment device produces cold plasma through a unit structure that includes a head and a body. The device includes one or more user controls, including a The device includes a plasma power switch and a light switch. The head includes one or more light-emitting diodes (LEDs). The skin treatment device also includes a plasma pulse control, configured to generate plasma at the head while the plasma pulse control is pressed. The skin treatment device includes a charging port for recharging an integrated battery. The skin treatment device includes internal electronic components that control the plasma.

[0140] The electronic components may include a unit structure having a DBD head and body. Cold plasma is produced between electrodes included in the DBD head, which serves as the treatment site. The DBD head is electrically connected to a high-voltage unit, which provides power to the DBD head. The energy required to drive the plasma is supplied by a rechargeable battery pack integrated within the body. The system includes one or more LEDs, connected to the system via a main PC board and control circuitry. The main PC board and control circuitry control the flow of electricity to the LED and the high-voltage unit, and receive input from one or more user commands and an external power supply to charge the rechargeable battery pack.

[0141] Without being related to the theory, the effect of cold atmospheric plasma therapy is thought to be due to some extent to the interaction between RONS and biological systems. A non-exhaustive list of RONS includes: hydroxyl (OH), atomic oxygen (O), singlet delta oxygen (O2('D)), superoxide (O2), hydrogen peroxide (H2O2), and nitric oxide (NO). Attack by hydroxyl radicals is thought to lead to the peroxidation of cell membrane lipids, which in turn affects cell-cell interaction, the regulation of membrane-protein expression, and many other cellular processes. Hydrogen peroxide is a potent oxidant, which is thought to have a detrimental effect on biological systems. Nitric oxide is thought to play a role in cell signaling and bioregulation.At the cellular level, nitric oxide is thought to affect the regulation of immune deficiencies, cell proliferation, phagocytosis, collagen synthesis, and angiogenesis. At the systemic level, nitric oxide is a potent vasodilator.

[0142] Cold atmospheric plasmas also expose biological surfaces to electric fields, on the order of 1–10 kV / cm. Cells are thought to respond to such fields by opening transmembrane pores. This electric field-induced cellular electroporation is thought to play a role in the transfusion of molecules across cell membranes. While not related to the theory, the efficacy of the treatment is believed to be due at least in part to long-lived plasma-generated species, which in an atmospheric plasma will be a variety of RONS at concentrations specific to the operating parameters of the cold atmospheric plasma source.

[0143] Although cold atmospheric plasma can also be used to ablate tissue or perform treatment in a very short time when used at high power and intensity, this treatment is thought to damage surrounding tissues and penetrate well beyond the treated area. Without being related to the theory, it is believed that low-intensity cold atmospheric plasma treatment avoids cell damage.

[0144] Without being related to the theory, it is thought that an important parameter for both direct treatment with cold atmospheric plasma and indirect treatment using plasma-treated media is the dose of plasma species imparted to the treatment surface. In general, this is expressed as the concentration of a given plasma species produced by the cold atmospheric plasma source that is delivered to a unit area of ​​the treated surface over a unit time.

[0145] Alternatively, the dose can be expressed as a simple time, if the treatment has been determined and the behavior of the cold atmospheric plasma source is well understood. For example, for a stable cold atmospheric plasma source and a uniform surface, a particular dose of a given RONS will be obtained after the cold atmospheric plasma has treated the uniform surface for a given time. In practice, surface conditions and plasma characteristics are coupled, where a variation in one induces changes in the other. A sudden change in surface moisture, for example, can affect the surface conductivity and lead to an increase in plasma intensity. Conversely, a sudden increase in plasma intensity can vaporize the surface moisture, producing RONS and surface changes.This variability necessitates control of the plasma treatment device, as explained in more detail below.

[0146] While not related to the theory, it is thought that cold atmospheric plasma treatment penetrates the treatment surface through a synergistic effect of electroporation, the permeability of plasma-generated species, and intercellular signaling. The so-called "bystander effect" is thought to play a role in the propagation of plasma-induced cellular changes away from the treatment surface and into a volume below. The bystander effect is thought to occur through chemical signals passed between cells in response to the introduction of a biologically active chemical, potentially amplifying the magnitude of the treatment's impact.

[0147] Experiments have shown that RONS include reactive nitrogen species (RNS for Reactive Nitrogen Species) and reactive oxygen species (ROS for Reactive Oxygen Species) which are expected to interact in different ways with various biological surfaces. In agarose films, for example, RONs permeate a volume beneath the film, whereas in living tissues, only RNSs do so. However, ROS penetrate gelatin and other liquids. ROS, being more reactive than RNSs, have a shorter lifespan and are thought to be linked, under certain circumstances, to aggressive or harmful effects on biological surfaces, as previously discussed with regard to hydrogen peroxide.

[0148] Cold plasma treatment with additional treatment devices

[0149] In some embodiments, a cold plasma system for treating a region of a biological surface includes a plasma treatment device, comprising an electrode and a dielectric barrier having one side facing the electrode and the other side facing away from the electrode. The system may include an auxiliary treatment device configured to enhance the effects of the cold plasma on the region. In one aspect, the auxiliary treatment device is selected from a group consisting of a vibrating device, a light source configured to illuminate the region, and an air source directed toward the region.

[0150] In one aspect, the vibration device includes a multi-axis eccentric mass vibrator. The vibration device may include a piezoelectric actuator.

[0151] In one aspect, the light source includes one or more light-emitting diodes, configured to direct light having a wavelength in a range of 400 to 500 nm towards the region.

[0152] In one aspect, the air source includes a duct configured to direct an airflow to the region, an air handling unit disposed within the duct, and one or more temperature control elements configured to regulate the temperature of the airflow. The air handling unit may include a fan. The temperature control elements may include at least one of a thermoresistive heating coil and a Peltier cooler.

[0153] In one aspect, the plasma treatment device further includes one or more actuation elements configured to repeatedly stretch and relax the biological surface in the region. In one aspect, the plasma treatment device further includes a cover placed over the dielectric barrier, and in which the cover is configured to protect the dielectric barrier from contact damage or contamination. The cover may be made of glass, plastic, or quartz.

[0154] In one aspect, the biological surface includes at least one of the following: skin, hair and nails.

[0155] In one aspect, the plasma is discharged at least partially into the biological surface.

[0156] In some embodiments, a method for treating a region of a biological surface with a cold plasma system includes generating the plasma by a plasma treatment device that includes a plasma generator. In some embodiments, the method includes applying the plasma to the biological surface, activating an auxiliary treatment device, treating the biological surface with the auxiliary treatment device, and stopping the plasma.

[0157] In one aspect, the treatment of the biological surface with the auxiliary treatment device includes the vibration of the plasma treatment device.

[0158] In one aspect, the treatment of the biological surface with the auxiliary treatment device includes the vibration of the biological surface at or near the region.

[0159] In one aspect, the treatment of the biological surface with the auxiliary treatment device includes irradiating the region with light from a light source disposed on the plasma treatment device. The light source may emit visible light. The light source may emit infrared light.

[0160] In one aspect, the treatment of the biological surface with the second treatment device includes supplying a circulating airflow to the region via a duct disposed within the plasma treatment device and an air handling unit disposed within the duct. In another aspect, the method includes cooling or heating the circulating airflow with one or more temperature control elements configured in the duct.

[0161] Cold plasma treatment system with external support devices

[0162] In some embodiments, a cold plasma system for treating a region of a biological surface includes a plasma treatment device, comprising an electrode and a dielectric barrier having a first side facing the electrode and a second side facing away from the electrode. In one aspect, the plasma treatment device further includes a rechargeable battery electrically connected to the electrode and functionally coupled to the power cell via a charging link. In some embodiments, the plasma treatment system further includes a support device external to the plasma treatment device.In some embodiments, the support device includes a power cell electrically connected to the plasma treatment device and a controller functionally coupled to the power cell and the plasma treatment device. In one aspect, the support device is wirelessly connected to the plasma treatment device. In another aspect, the support device is electrically connected to the plasma treatment device via a detachable cable.

[0163] In one aspect, the dielectric barrier and the electrode are arranged on a retractable support, the extension of which positions the second side of the dielectric barrier for treating the region, the retractable support being disposed within a housing. In one aspect, the plasma treatment device is a device the size of a lipstick.

[0164] In one aspect, the support device is an intelligent device. The intelligent device can be selected from a group consisting of a smartphone, a tablet, a laptop computer, an electronic hair styling device and a plasma device including a charging station.

[0165] In one aspect, the plasma is discharged at least partially into the biological surface.

[0166] In one aspect, the biological surface includes at least one of the following: skin, hair or nails.

[0167] In some embodiments, a cold atmospheric plasma system for treating a region of a biological surface includes a plasma treatment device. The plasma treatment device may include an electrode and a dielectric barrier having one side facing the electrode and the other side facing away from the electrode. In some embodiments, the dielectric barrier and the electrode are arranged on a retractable support whose extension positions the second side of the dielectric barrier for treating the region, the retractable support being disposed within a housing. In some embodiments, the plasma treatment device includes a battery electrically connected to the electrode and a controller functionally coupled to the battery and the electrode, configured to receive data and send control inputs. The system may be the size of a lipstick.

[0168] In some aspects, the battery is a rechargeable battery, integrated into the device.

[0169] In certain aspects, the plasma treatment device is configured to Connect to an external support device connected to the plasma treatment device via a detachable cable. The support device can be configured to provide power and control inputs to the plasma treatment device.

[0170] In some embodiments, a method for treating a region of a biological surface with a cold atmospheric plasma system includes attaching a detachable cable to the plasma system and transferring power and control inputs to the plasma system from a support device via the detachable cable. In some embodiments, the method further includes generating a cold atmospheric plasma between the plasma system and the region, stopping the cold atmospheric plasma, and detaching the detachable cable from the plasma system.

[0171] In some aspects, the method includes extending a retractable support carrying an electrode and a dielectric barrier, the support being disposed within the plasma treatment device, which, when extended, positions the dielectric barrier to generate cold atmospheric plasma near the region. The method may include retracting the retractable support.

[0172] In some aspects, the process includes wireless power transfer to the plasma system, in which the plasma system includes a rechargeable battery.

[0173] Cold plasma treatment system with formulation dispensing

[0174] In some embodiments, a cold plasma system for treating a region of a biological surface includes a plasma generator and a pretreatment formulation. In some embodiments, the cold plasma system includes an electrode and a dielectric barrier having a first side facing the electrode and a second side facing away from the electrode. In one aspect, the system further includes a posttreatment formulation configured for application to the region of the biological surface.

[0175] The pretreatment formulation can be configured for application to the biological surface area. In one aspect, the pretreatment formulation comprises plasma-treated species. In one aspect, the pretreatment formulation comprises one or more of a fragrance, an essential oil, a pigment, and an active ingredient.

[0176] In one aspect, the biological surface includes at least one of the following: skin, hair and nails.

[0177] In one aspect, the plasma is discharged at least partially into the pre-treatment formulation.

[0178] In embodiments, a method for treating a region of a biological surface with a cold plasma includes the selection of a pretreatment formulation, the application of the pretreatment formulation to the region, the generation of a cold plasma between a plasma treatment device and the pretreatment formulation, and the stopping of the cold plasma.

[0179] In one aspect, the process includes removing the pretreatment formulation from the region. The process may include, prior to applying the pretreatment formulation to the region, treating the pretreatment formulation by discharging cold plasma into the pretreatment formulation. In another aspect, the process includes selecting a posttreatment formulation and, after stopping the cold plasma, applying the posttreatment formulation to the region.

[0180] In one aspect, the process includes the removal of the post-treatment formulation from the region.

[0181] In embodiments, a method for treating a region of a biological surface with a cold plasma-treated formulation includes the selection of a formulation, application of cold plasma to the formulation, stopping of cold plasma and application of the formulation to the region.

[0182] In one aspect, the process includes the removal of the formulation.

[0183] In one aspect, the process includes, after application of the formulation to the region, the unloading of cold plasma into the formulation.

[0184] In one aspect, the process includes selecting a post-treatment formulation and applying the post-treatment formulation to the area after application. The process may include removing the post-treatment formulation from the area.

[0185] Cold plasma treatment with modular system

[0186] In embodiments, a modular cold atmospheric plasma system for treating a region of a biological surface includes a plasma generator body and a head that is removably attached to the plasma generator body. The head may have a mounting side facing the generator body and an application side configured to face the biological surface. The application side of the head may carry an electrode and a dielectric barrier having a first side facing the electrode and a second side facing away from the electrode.

[0187] In some aspects, the plasma is discharged at least partially into the biological surface.

[0188] In some aspects, the biological surface includes at least one of the following: skin, hair or nails.

[0189] In some aspects, the head is tapered from a first dimension on the mounting side to a second dimension on the application side. The second dimension may be smaller than the first dimension. In some aspects, the second dimension is larger than the first dimension, and the electrode and the dielectric barrier are configured to produce a cold atmospheric plasma over an enlarged portion of the treatment region on the biological surface compared to a size on the application side.

[0190] In some aspects, the head is a formula application head that includes a reservoir for a liquid formula and an exudation surface connected to the reservoir via one or more conduits, wherein the exudation surface is configured to allow the liquid formula to flow onto the area. In some aspects, the head includes a flexible skirt on the application side of the head, and wherein the flexible skirt is configured to conform to the biological surface by compressing the flexible skirt between the biological surface and the head. The flexible skirt may include a rigid spacer that restricts the compression of the flexible skirt between the application side of the head and the biological surface.

[0191] In some aspects, the head includes a plasma filter positioned between the dielectric barrier and the region. The plasma filter may include at least one of a chemical filter, an ultraviolet filter configured to block the transmission of ultraviolet photons, and a charged species filter that includes a conductive surface configured to neutralize anions, cations, and free electrons. In some aspects, the chemical filter includes at least one of activated carbon, graphene, a catalyst, and a radical scavenging material. The plasma filter may be configured to at least partially cover the biological surface region.

[0192] In certain aspects, the application side of the head includes a conformable material at least partially surrounding the dielectric barrier material, wherein the conformable material conforms to the contours of the region. Both the electrode and the dielectric barrier may be conformable to the contours of the region.

[0193] In certain aspects, the head includes one or more air outlets on the application side of the head, configured to provide a cushion of air circulating around the dielectric barrier, and an air-handling device, enclosed inside the air-cushion head, configured to supply circulating air to the air outlets.

[0194] In certain aspects, the electrode is pixelated into individually activated zones capable of generating cold plasma. The system may include a controller configured to power the activated zones of the electrode.

[0195] In embodiments, a method for treating a region of a biological surface with a modular cold atmospheric plasma system includes selecting a head from a plurality of removable heads, attaching the head to a generator body, generating a cold plasma between the plasma system and the region, and stopping the cold plasma.

[0196] In some aspects, the method includes the fact that the head is tapered from a first dimension on one side mounting the generator body to a second dimension on one side application of the head.

[0197] In certain aspects, in which the head carries a formula, the method further includes supplying the formula to the application side of the head via an exudation opening, and applying the liquid formula to the biological surface region. In certain aspects, in which the head is configured to filter plasma, the method further includes generating cold plasma through a plasma filter and applying the cold plasma to the biological surface region through the filter.

[0198] In some aspects, the process includes the filtration of plasma through a liquid formula applied to the biological surface region.

[0199] In certain aspects, in which the head is an air cushion head, the method includes the activation of an aerodynamic device which is located within the head and the provision of an air cushion circulating around a dielectric barrier of the head.

[0200] In some aspects, the head is a flexible head conformable to the biological surface at the level of the region.

[0201] In some aspects, the generation of the cold atmospheric plasma between the plasma system and the region includes the application of a flexible skirt against the region, in which the flexible skirt surrounds a dielectric barrier of the head and contains the cold atmospheric plasma in a space between the region, the flexible skirt and the head.

[0202] Cold plasma treatment with sensors and controlled plasma generation

[0203] In embodiments, a cold plasma system for treating a region of a biological surface includes a plasma treatment device, comprising an electrode and a dielectric barrier having a first side facing the electrode and a second side backing the electrode. The system may include one or more sensors. The sensors may measure properties of at least one cold plasma, the ambient environment around the system, and the biological surface. The system may include a controller functionally coupled to the plasma treatment device and to at least one of the sensors. The controller may receive input from the sensors to determine control data for the plasma treatment device and send control data to the plasma treatment device.

[0204] In one aspect, the electrode is pixelated into a plurality of zones that are individually addressable by the controller.

[0205] In one aspect, the one or more sensors include a sensor placed on or near the biological surface region.

[0206] In one aspect, one or more sensors include one or more motion sensors. In one aspect, one or more sensors include a humidity sensor configured to measure ambient air humidity. In one aspect, one or more sensors include a reactive oxygen sensor. In one aspect, one or more sensors include a light sensor. In one aspect, one or more sensors include a plasma conductivity sensor. In one aspect, one or more sensors include a surface temperature sensor. In one aspect, one or more sensors include a distance sensor. In one aspect, one or more sensors include an ion concentration sensor.

[0207] In one aspect, the plasma is discharged at least partially into the biological surface.

[0208] In one aspect, the biological surface includes at least one of the following: skin, hair and nails.

[0209] In one aspect, the cold plasma system further includes a ballast circuit connected to the electrode.

[0210] In one aspect, the cold plasma system further includes a non-transient, computer-readable medium having computer-executable instructions stored on that which, in response to the execution by one or more processors of a computer device, causes the computer device to perform actions including the determination of a plasma uniformity as a function of time, the determination of a dose of one or more plasma-generated species and the modulation of the plasma as a function of time to control the uniformity and the dose.

[0211] In one aspect, the cold plasma system further includes a formulation engine which, in communication with the controller, determines a target plasma dose and a set of plasma parameters necessary to deliver an application dose and a data storage system which stores data relating to the application dose.

[0212] In some embodiments, a method for treating a region of a biological surface with cold plasma includes generating the cold plasma between a plasma source and the region and measuring one or more treatment parameters with one or more sensors. In some embodiments, the method includes determining a plasma dose from the treatment parameters, modulating one or more of the treatment parameters to adjust the plasma dose, and stopping the cold plasma.

[0213] In one aspect, the method includes at least one sensor carried by the plasma source.

[0214] In one aspect, the method includes at least one sensor carried by the biological surface.

[0215] In one aspect, the method includes moving the plasma source while The plasma source generates the cold plasma.

[0216] In one aspect, the method includes providing a perceptible signal when the plasma dose is outside a safe range or an effective range.

[0217] In one aspect, the method includes determining a discharge voltage as a function of time, determining a discharge current as a function of time, determining a plasma temperature as a function of time, and determining a near-region gas temperature as a function of time.

[0218] In one aspect, the process includes, prior to plasma generation, placing at least one of the sensors on the biological surface at or near the region, exposing at least one sensor to the plasma, and, after plasma generation, removing at least one sensor.

[0219] In one aspect, the method includes automating the determination of a treatment dose by determining the treatment dose via a formulation engine that is in communication with a data storage system, determining a set of plasma parameters to achieve the treatment dose during treatment of the region, and supplying the treatment dose and the set of plasma parameters to the plasma source.

[0220] In one aspect, the method includes intermittently redefining the treatment dose by remeasuring plasma parameters during cold plasma treatment.

[0221] In one aspect, the method includes the determination of a plasma uniformity indicator; and the modulation of one or more plasma parameters in response to changes in the indicator.

[0222] In one aspect, the method includes the measurement of plasma parameters in a group including a current supplied to the discharge, a driving frequency, a voltage waveform, a peak-to-peak voltage, a root mean square voltage, a plasma temperature, a gas temperature and optical emission from the plasma.

[0223] In one aspect, the method includes generating plasma using a plurality of pixelated electrodes arranged in a matrix, and determining a discharge power for a given pixelated electrode. In another aspect, the method includes modulating the discharge power for the given pixelated electrode if the plasma has localized to that specific pixelated electrode.

[0224] Cold plasma system with additional processing devices

[0225] A cold plasma treatment system provides cosmetic treatment to a region of a consumer's biological surface. In some embodiments, the system includes a cold atmospheric plasma treatment device comprising a plasma generator having an electrode and a dielectric barrier.

[0226] In some embodiments, the plasma treatment device includes a vibration device. While not related to the theory, it is believed that actuation of the vibration device provides the consumer with an enhanced treatment experience and improves treatment efficacy by mitigating plasma non-uniformity over the area. In some embodiments, the vibration device may emit ultrasonic vibrations. In operation, the ultrasound may enhance the transport of active plasma species into the tissue (or across diffusion barriers, generally), thereby increasing the efficacy of cold plasma treatment.

[0227] The vibration device can cause the treatment device to vibrate, thereby affecting the distance L between the second side of the dielectric barrier and the biological surface. In some embodiments, the vibration device vibrates the treatment device along multiple axes simultaneously. In other embodiments, the vibration device vibrates the treatment device along a single axis. The vibration device can cause the treatment device to vibrate so that the plasma moves parallel to the biological surface along one or two axes. Such movement is thought to distribute the plasma in the region, thereby improving plasma uniformity. The vibration device may include one or more vibration sources, such as a piezoelectric actuator or a multi-axis eccentric mass vibrator.

[0228] In some embodiments, the plasma treatment device directly actuates the biological surface by means of one or more actuation elements. While not related to the theory, it is believed that the repeated tension and compression of the biological surface enhance the efficacy of multimodal treatment by stimulating synergistic effects with the permeability of the plasma-generated species and the consumer's experience of the treatment. The actuation elements may be in direct contact with the biological surface at or near the region. In some embodiments, the actuation elements move in opposite directions to each other, parallel to the biological surface. The actuation elements may move closer together, compressing and releasing the biological surface in turn. The actuation elements may move away from each other, stretching and releasing the biological surface in turn.In some embodiments, the actuation elements move both closer to and further from each other, thereby simultaneously stretching and compressing the biological surface. In other embodiments, plasma is generated towards the region while the actuation elements actuate the biological surface.

[0229] Actuation can be achieved through ultrasound emitted by the vibrating device. In various embodiments, the ultrasound can be transmitted to the target biological surface via actuation elements capable of generating ultrasound. In some embodiments, the actuation elements form an annular shape with the electrode and dielectric barrier contained within the annular shape. In other embodiments, an ultrasound source can include multiple orifices for directing the cold plasma to the biological surface. During operation, an acoustic coupling medium can couple the ultrasound source (e.g., the actuation elements) to the biological surface. Some non-exclusive examples of such coupling media are hydrogels, solid gel packs, etc.The coupling medium can be formulated to have additional ingredients and properties to enhance the experience, such as precursors and ingredients that can be activated by and / or work with plasma, a fragrance, etc. In some embodiments, no coupling gel is used, and the ultrasound source couples sufficient energy to the biological surface even in the absence of a coupling medium. The actuation devices can actuate the surface without exposure to plasma, thus providing a tactile experience for the consumer.

[0230] In addition to plasma treatment, the plasma treatment device may include a light source, configured to illuminate the region with light in the area described by the characteristic dimension T. As previously described, irradiation of the biological surface with light having a wavelength in the 400–500 nm range is thought to offer desirable therapeutic results for the cosmetic treatment of imperfections. In some embodiments, the plasma treatment device includes multiple light sources. The light source may include one or more light-emitting diodes (LEDs), each individually emitting light with a wavelength in a target range.

[0231] The light source may include an infrared light element, providing radiative heating to the biological surface. While not related to the theory, it is believed that radiative heating of the biological surface enhances the therapeutic effect of plasma therapy by triggering a response of the biological surface to plasma-generated species and providing an enhanced experience for the consumer.

[0232] The plasma treatment device may include a cover disposed on or above the dielectric barrier. The cover may, but is not limited to, be made of plastic, glass, or quartz, and may prevent plasma-generated species from reaching the biological surface. While not theoretically based, it is believed that plasma can emit ultraviolet photons under certain conditions. Therefore, it may be desirable to block the transmission of ultraviolet photons using a cover.

[0233] In some embodiments, the plasma treatment device includes an air source that directs an airflow to the region within the area described by the characteristic dimension T. The air source may include an air-handling device, such as a fan or blower, disposed within an air duct that is shaped to provide the airflow to the surface of the region. In some embodiments, one or more temperature control elements disposed within the plasma treatment device adjust the air temperature. Non-limiting examples of temperature control elements include thermoelectric cooling elements such as Peltier coolers, electric heating elements such as ohmic heating coils, etc.In some embodiments, a volatile oil containing a fragrance is placed within the air duct so that, when the air handling unit is active, the oil imparts a pleasant aroma to the area. Small device

[0234] In some embodiments, the plasma treatment device is electrically connected to an external device having a power cell and a controller. In some embodiments, the plasma treatment device is electrically connected to the external device via a cable. In some embodiments, The cable carries control inputs and electrical power to the plasma treatment device. In some embodiments, the cable is detachable from the plasma treatment device, the external device, or both. The power cell can be a rechargeable battery, including, for example, a lithium-ion battery. The controller can be capable of receiving data and sending control signals to the plasma treatment device.

[0235] In some embodiments, the plasma treatment device includes a battery electrically connected to the electrode. The battery may be rechargeable, charged by connecting the cable to the plasma treatment device and a power source. Some non-limiting examples of such a power source are the external device, an adapter connected to a standard wall outlet providing electricity, a solar cell, etc. In some embodiments, the battery is charged wirelessly. In some embodiments, the battery is a commercially available battery, such as a battery of one of the A series types ("A", "AA", or "AAA").

[0236] In some embodiments, the external device is a smartphone. In some embodiments, the external device is a laptop or tablet, configured to be compatible with the plasma treatment device and to provide power and control inputs to the external device. In some embodiments, the external device is a cosmetic tool, including, but not limited to, an electronic beard trimmer, a hair straightener, a hair dryer, an electronic epilator, etc. The external device may be a large-area plasma treatment device, as described above, further including a charging station for an electrical connection to the plasma treatment device.In some embodiments, the charging station is configured to accept the plasma processing device, which can be functionally mounted within the large-area device for compact charging and operation as a plasma generator. In some embodiments, the electrode and the dielectric barrier are arranged behind a cover. The cover may be removable. The cover can serve as protection for the dielectric barrier when the plasma processing device is not in use.

[0237] In some embodiments, the electrode and the dielectric barrier are arranged on a retractable support enclosed within the plasma treatment device. The retractable support can be configured so that, when retracted, the dielectric barrier and the electrode are hidden from view and the plasma treatment device cannot be activated. The retractable support can be rotated by means of a mechanism located at one end of the plasma treatment device opposite the dielectric barrier, so that the dielectric barrier emerges from the end The opposite of the plasma treatment device is in a manner resembling a lipstick tube. The plasma treatment device may have a form factor similar or comparable to a retractable lipstick tube, so that it resembles the lipstick tube when inactive. In some embodiments, the retractable support is a linear slide that is configured to slide the electrode and the dielectric barrier behind the shielding when not in use.

[0238] In some embodiments, the plasma treatment device is controlled via a user interface in the external device. In some embodiments, the external device is any type of device including a battery, a general-purpose computer, and a computer-readable memory with instructions stored on it which, when executed by the computer, implement a process for treating a region of a biological surface with cold atmospheric plasma.

[0239] In some embodiments, the plasma treatment device includes one or more user controls, including, but not limited to, a power switch, a plasma intensity selector, and a safety switch. The plasma treatment device can be switched on and off using a power switch located on the plasma treatment device, and plasma is generated while the plasma treatment device is switched on. In some embodiments, a safety switch prevents the plasma treatment device from switching on until the safety switch is disengaged. In some embodiments, the safety switch is a fingerprint reader. In some embodiments, a plasma intensity selector allows for smooth and continuous modulation of the plasma intensity, in terms of the power supplied to the electrode.In some embodiments, the plasma intensity selector limits the plasma treatment device to one of a number of discrete intensity settings, in terms of incremental steps in the power supplied to the electrode.

[0240] In some embodiments, the plasma treatment device includes one or more light-emitting diodes (not shown), providing therapeutic light to the biological surface. In some embodiments, the light-emitting diodes provide blue light in the 400-500 nm range. Cold plasma with formulation distribution

[0241] In some embodiments, the plasma treatment device, including the dielectric barrier and the electrode, discharges plasma into the biological surface via a formulation. The formulation may include one or more active ingredients, including, but not limited to, antioxidants, radical scavengers, ultraviolet-absorbing compounds, rejuvenating compounds, etc. In some embodiments, the radical scavenger compound is a formula Anhydrous glycol in silicone with ascorbic acid and ascorbyl glucoside. In some embodiments, the radical scavenger compound is a water-in-silicone emulsion with a large internal aqueous phase incorporating water-soluble active ingredients. While not bound by theory, it is believed that the aqueous phase will form encapsulations containing the active ingredients. The rejuvenating compounds may include collagen, elastin, and the like. The formulation may include inactive ingredients such as dyes, pigments, fragrances, essential oils, emulsifiers, viscosity modifiers, etc. In some embodiments, the dye may be chemically reactive and may respond to pH changes induced by plasma exposure.

[0242] A plasma is discharged into the formulation in a container before application to the biological surface at or near the target area. While not theoretically supported, the plasma is believed to generate beneficial species, including ions, radicals, and long-lived RONs. The plasma treatment device can generate the plasma near the formulation by placing the device close to the exposed surface of the formulation while it is in the container.

[0243] In some embodiments, a pre-treatment formulation enhances the effects of plasma exposure by including reactive compounds to generate RONS. In some embodiments, a post-treatment formulation reduces the potentially harmful effects of prolonged exposure to plasma-generated species. For example, the post-treatment formulation can control the pH change of the region after exposure to plasma-generated species by including buffering compounds.

[0244] A treatment method using a plasma treatment device to generate plasma between the plasma treatment device and the biological surface, which includes at least one formulation. In embodiments, the method may include additional steps or may be carried out without all the steps illustrated in the flowchart.

[0245] The process starts and proceeds to a pretreatment phase, including the selection of a formulation and its application to the area. As described previously, the formulation may have protective or enhancing properties that improve therapeutic outcomes after plasma exposure. In some embodiments, the formulation is chosen to reduce exposure of the area to ultraviolet photons produced in the plasma, or to enhance the production of RONs, etc.

[0246] In some embodiments, a pre-treatment formulation is applied to the area before exposure to the plasma. The process then continues, which includes the Plasma generation. The plasma treatment device can generate plasma near the area. Block plasma treatment can continue until the plasma stops. In some embodiments, the process then continues, where a post-treatment formulation is selected. The post-treatment formulation can be applied to the area after plasma exposure. The pre-treatment and post-treatment formulations can be the same or different and selected to provide different effects to the area. The process terminates. In some embodiments, the process includes the removal of the pre-treatment formulation after plasma treatment. In other embodiments, the process includes the removal of the post-treatment formulation after its application. Modular cold plasma generator device

[0247] In some embodiments, the system includes a treatment device body and a head that is removably attached to the treatment device body. The illustrated head has a mounting side facing the treatment device body and an application side bearing an electrode, and a dielectric barrier has a first side facing the electrode and a second side facing away from the electrode. The cold plasma system may include a plurality of attachable heads for cosmetic treatment of a region of a biological surface. The biological surface includes, but is not limited to, the skin, hair, nails, etc.

[0248] In some embodiments, a head is selected to produce the cold plasma for performing a particular treatment. For example, when treating a relatively small area on the biological surface, a plasma size may be chosen to avoid exposing the non-target portion of the biological surface to plasma-generated species. Here, the term "plasma size" refers to a characteristic or descriptive dimension of the plasma. For example, for a plasma generated by a round electrode, the characteristic dimension of the plasma is related to the electrode diameter.

[0249] A head can be selected and attached to the body of the treatment device. The head tapers from a larger size on the mounting side to a smaller size on the application side. Consequently, the head generates plasma whose characteristic size differs from the diameter of the head's mounting side. Although the head may have a smaller application side than its mounting side, it should be understood that the reverse is also possible. For example, the head may have a larger application side than its mounting side to deliver low-intensity treatment to a region of the biological surface.

[0250] As illustrated, a head may include a formula reservoir and an exudation surface on the application side of the head. The exudation surface may be connected to the formula reservoir via one or more conduits. In embodiments, The formula exudation surface includes one or more nozzles on the application side of the head. In some embodiments, the formula exudation surface is a porous material with an empty volume to cushion the flow of formula from the exudation surface. The porous material may include a cured gel, a flexible plastic foam, a rigid plastic foam, a natural porous material such as pumice, etc. In some embodiments, the formula exudation surface may include a vent barred by one or more grids, a wire mesh screen, a patterned perforated screen, etc. In some embodiments, the formula reservoir is compressed by pressure when the application side of the head is applied to the biological surface.In some embodiments, the formula reservoir is compressed by a mechanism enclosed within the head, including, but not limited to, an electric actuator, a servomechanism, a manually operated lever, a roller, a pair of rollers, etc. In some embodiments, the formula reservoir is removable and interchangeable, and contains a prepared formula adapted to a desired therapeutic or cosmetic result.

[0251] In some embodiments, the formula includes one or more cosmetic ingredients. Cosmetic ingredients may include a fragrance, pigment, cream, oil, natural extract, moisturizer, etc. In some embodiments, the formula includes one or more drugs, for example, astringents, pharmaceutically active compounds, acid-neutralizing creams, antioxidants, etc. In some embodiments, the formula includes one or more protective compounds to protect the biological surface from potentially harmful effects of plasma exposure. Some non-limiting examples of such protective compounds are an antioxidant, a moisturizer, a clarifying cream, an acid-buffering cream, etc.

[0252] In some embodiments, the head includes a flexible skirt on the application side of the head. In some embodiments, the flexible skirt is made of corrugated plastic or soft rubber and is attached to the application side of the head. In some embodiments, the flexible skirt is compressed by contact with the biological surface. In some embodiments, the flexible skirt includes a rigid spacer, restricting the compression of the skirt and thus defining a minimum gap between the head and the biological surface. In some embodiments, the flexible skirt is impermeable to gases and, when compressed, creates a confined environment for plasma formation. The rigid spacer may be enclosed by the flexible skirt or may be external to it and may be added or removed. In some embodiments, the rigid spacer includes a conductive material, including, but not limited to, a metal.In some embodiments, the rigid spacer including a conductive material is biased at a voltage greater than or equal to zero. Without being connected to the... In theory, it is thought that the rigid spacer, thus polarized, can allow plasma to form between the head and the rigid spacer, thereby reducing the dose of ions and electrons directed towards the biological surface. In some embodiments, the plasma discharged into the rigid spacer produces RONs that are contained within the volume defined by the flexible skirt.

[0253] In some embodiments, the head includes a filter for filtering the plasma. The filter can be placed between the head and the biological surface, for example, in a path of the plasma applied to the biological surface.

[0254] In some embodiments, the filter is an ultraviolet filter, positioned at least partially to block the path of ultraviolet photons from the plasma to the biological surface. In some embodiments, the filter blocks ultraviolet photons because the filter is made of a UV-absorbing or dispersing material, including, but not limited to, plastic, glass, or quartz treated with a UV-blocking film, etc.

[0255] In some embodiments, the filter is a chemical filter designed to sequester or convert one or more plasma-generated species that would otherwise reach the biological surface. In some embodiments, the filter includes a carbonaceous material, non-limiting examples of which include graphene, carbon nanotubes, activated carbon paper, carbon fiber, etc. In another embodiment, the filter includes a catalytic material, non-limiting examples of which include metallic particles embedded in a porous matrix. In some embodiments, the filter includes radical-scavenging materials, for example, antioxidants, including catalases, glutathione peroxidase, superoxide dismutase (SOD), α-tocopherol (Vit. E), ascorbic acid (Vit. C), β-carotene (Vit. A), selenium, etc.In some embodiments, the filter includes a pH-sensitive polymer that responds to changes in proton concentration by altering its porosity, surface properties, dimensions, etc. Some non-limiting examples of such pH-sensitive polymers include polyacids and polybases, chitosan, hyaluronic acid, and dextran. In other embodiments, the filter responds to pH changes by opening pores and releasing one or more of the radical-scavenging materials described above.

[0256] In some embodiments, the filter includes a liquid formula that is applied to the biological surface upon contact. The liquid formula may include any of the aforementioned filtering materials, carried in a liquid emulsion including, but not limited to, a cream or an oil. In some embodiments, the liquid formula filter includes additional materials such as cosmetic ingredients, medical ingredients, etc. In some embodiments, the liquid formula includes an indicator material that provides a colorimetric indicator. exposure to plasma-generated species. In some embodiments, the indicator material is a pH-sensitive dye that will change color when the biological surface has been exposed to a concentration of plasma-generated acidifying or alkalizing species sufficient to alter the molecular structure of the dye. Non-limiting examples of pH-sensitive dyes include gentian violet, methyl yellow, methyl red, cresolphthalein, indigo carmine, etc.

[0257] In some embodiments, the filter includes a charged particle filter placed between the plasma and the biological surface that attracts and neutralizes charged particles present in the plasma. In some embodiments, the charged particle filter includes one or more conductive elements, individually polarized to a non-zero voltage. Non-limiting examples of a conductive element include a metal sieve, a metal probe, a metal ring, etc., placed near or around the dielectric material on the application side of the head. In some embodiments, the charged particle filter selectively filters positive ions by having a negative polarity, thus neutralizing the positive ions that approach the filter surface.In some embodiments, the charged particle filter filters all charged particles by combining several conductive elements, for example, at least one conductive element carrying a negative polarity and at least one conductive element carrying a positive polarity.

[0258] The biological surface may include contours that can affect the uniformity of plasma exposure in the affected area. Non-limiting examples of contoured biological surfaces include areas on the face and body, including, but not limited to, convex surfaces such as the cheekbones, chin, eyebrows, nose, jaw, finger joints, ankles, elbows, knees, etc. Similarly, contoured biological surfaces may include concave surfaces, such as in the area under the jaw, around the ears, along the neck, etc. In some embodiments, a head includes a conformable material on the application side. The conformable material is configured to reversibly conform to the contours of the area. Non-limiting examples of the conformable material include a gel, a cured foam, rubber, plastic, etc.In some embodiments, the conformable material on the head includes a consumable material, for example a dry solid, a moisturizing gel, a water-soluble cream, etc.

[0259] In some embodiments, the application side of the head is reversibly conformable with respect to the biological surface. In some embodiments, the dielectric barrier includes a flexible surface, including, but not limited to, a woven dielectric fabric, such as a glass fabric, a ceramic fabric, etc. In some embodiments, the electrode includes a flexible conductive surface, such as woven wire mesh, copper mesh, stainless steel mesh, etc. In some embodiments, the flexible surface within the dielectric barrier is sealed to prevent the accumulation of abraded material from the biological surface during plasma treatment. The flexible surface may be sealed with a coating including, but not limited to, Teflon, a SiOx film, graphene, etc.

[0260] A head can provide an air cushion between the head and the biological surface. In some embodiments, the head includes a plurality of air ducts that at least partially surround the electrode and the dielectric barrier. During operation, the air delivery system supplies air to the air ducts (e.g., nozzles, vents, etc.) which direct a guided airflow away from the head. The airflow can create an air cushion that prevents or at least minimizes contact between the head and the biological surface. In some embodiments, the air delivery system is an electric fan located within the head. The air delivery system can operate independently of the electrode and can be switched on and off without altering the state of the plasma. Cold plasma device with sensors

[0261] In some embodiments, the cold plasma treatment device includes one or more sensors for measuring plasma parameters. Based on the measured plasma parameters, a controller can control the cold atmospheric plasma and maintain a predetermined cosmetic treatment on a region of a biological surface.

[0262] As described previously, in some embodiments, cold atmospheric plasma is formed using the biological surface as a floating reference electrode. While not related to the theory, it is thought that such an arrangement is sensitive to a non-uniform distribution of water and ion concentrations on the biological surface. It is thought that a localized region that is relatively ion-rich, such as a sweat gland, can provide a preferred conducting pathway for plasma-generated charged species, and that cold atmospheric plasma can preferentially form at such a site on the biological surface. In turn, plasma preference for one particular location over another on a biological surface introduces poorly controlled non-uniformity in the treatment and variability in the plasma dosage over the plasma-treated region.Uniformity is considered an important criterion in the operation of a cold atmospheric plasma source. Therefore, in embodiments, the... The design of the plasma treatment device takes into account the sensitivity of the cold atmospheric plasma to variations in surface properties.

[0263] Plasma uniformity is defined in terms of the variability of one or more plasma parameters, for example, discharge power, discharge volume, concentrations of plasma-generated species, etc. In a highly variable system, for example, where the treatment region contains many discrete subregions with disparate properties, the plasma treatment device may exhibit discontinuities in the discharge current or discharge voltage when the plasma treatment device moves between ion-rich and ion-poor subregions of the surface. While not bound by theory, it is thought that a plasma source, passing over a conductive subregion, may exhibit a peak in discharge current and a corresponding drop in discharge voltage.

[0264] In some embodiments, the controller actuates an electronic ballast circuit connected to the electrode. While not directly related to the theory, it is thought that an electronic ballast circuit can enable the controller to regulate the current to the electrode, thereby preventing thermal runaway of the plasma and restricting the plasma to one or more localized areas on the biological surface.

[0265] The plasma source incorporates one or more sensors for measuring parameters of a cold atmospheric plasma and a biological surface. In some embodiments, the plasma treatment device includes sensors that measure plasma parameters. Plasma parameters may include measurements of the electric current discharged into the biological surface, the voltage drop between the dielectric barrier and the surface. Plasma parameters may also include one or more parameters indicative of the plasma energy density, such as the spectrum of light emitted by the plasma, the ion density in the plasma, or the time variation of the aforementioned parameters that would indicate non-uniform surface treatment.Without being linked to the theory, it is thought that one or more short-lived discontinuities in the discharge voltage or discharge current indicate a non-uniformity in the form of a preference of the cold atmospheric plasma for one or more highly localized ion-rich regions at the surface.

[0266] In embodiments, one or more sensors, placed on the surface at or near the treatment area, measure parameters of the plasma or biological surface. For example, the plasma treatment device may include ion sensors, such as pH or chloride sensors, light sensors, reactive oxygen sensors, a surface temperature sensor, a distance sensor, humidity sensors, etc.

[0267] In some embodiments, sensors placed either on the surface or on the plasma treatment device measure the ambient environment. Such sensors may include ion sensors, light sensors, reactive oxygen sensors, temperature sensors, humidity sensors, etc.

[0268] In some embodiments, a position reference sensor placed on the plasma treatment device is functionally coupled to a distance sensor on the biological surface. The position reference sensor can determine the distance between the dielectric barrier and the surface. In other embodiments, a distance sensor, such as a laser rangefinder included in the plasma treatment device, measures the distance between the dielectric barrier and the surface.

[0269] In some embodiments, the sensors communicate with the controller, which is part of the plasma source. The controller can be functionally coupled to the plasma processing device and can receive input from the sensors and process this input to determine control data for the plasma processing device. In some embodiments, the control data includes, but is not limited to, signals sent to electronic components of the plasma processing device to modulate the current or voltage supplied to the electrode, and signals sent to other components of the plasma processing device to produce a perceptible signal. In some embodiments, the perceptible signal is haptic feedback or an audible or visual indicator.In some embodiments, the controller sends control data in response to a dangerous dose of energy or reactive species produced by the plasma.

[0270] As described above, without being related to the theory, a plasma dose is thought to determine exposure to one or more plasma-generated species such as reactive chemical species, energetic species including ions and electrons, photons, etc.

[0271] In some embodiments, a plasma dose is a concentration of a given species imparted to a given region on the biological surface over a period of time, expressed as a number per unit area per unit time (such as "per square centimeter per second"). In some embodiments, the controller determines a treatment time and control data to be sent to the plasma treatment device, integrating the plasma dose over the surface of the dielectric barrier, to deliver a plasma dose per unit time. In some embodiments, when the plasma treatment device remains on a given region of the biological surface for a duration such that the plasma is likely to damage the surface, the plasma treatment is considered hazardous.Conversely, in some embodiments, if the treatment device remains on the given area for such a long time that the plasma is unlikely to have the desired effect, the plasma treatment is considered to have delivered an ineffective dose. In various embodiments, these doses are not unique values, but rather are expected to occur within ranges. As such, a controller can determine a dangerous or ineffective dose range, within which it will send control data to the plasma treatment device to produce a perceptible signal, modulate the plasma, or both.

[0272] In some embodiments, the controller responds to a dangerous dose by sending a signal to move the source away from the region on the biological surface to a second region. The controller may respond to a dangerous dose by sending control data to the electronic components of the plasma treatment device to shut off the plasma, or to modulate the power supplied to the electrode in order to reduce the generation of energetic and reactive species in the plasma.

[0273] In some embodiments, the plasma is generated by a plurality of pixelated electrodes arranged in a matrix. The pixelated electrodes may be individually addressable by the controller, where the controller determines a discharge power for a given pixelated electrode. In some embodiments, the controller uses current and voltage sensor inputs for the pixelated electrodes to compensate for a restriction or non-uniform localization of the plasma. In some embodiments, when the plasma localizes to a location on the biological surface having disparate chemical or physical properties, the controller receives input indicating which pixelated electrodes are drawing a disproportionate rate of electrical power, compared to the average for the matrix.The controller can modulate the plasma by deactivating electrodes that draw excess power, thereby distributing plasma energy to the operational O electrodes, and reducing the undesirable effects of plasma non-uniformity near the non-operational NO electrodes.

[0274] The components of the cold plasma system can communicate directly via wired and powered connections. These components can communicate with each other via a network (not shown), which may include a suitable communication technology including, but not limited to, wired technologies such as DSL, Ethernet, fiber optics, USB and Firewire; wireless technologies such as Wi-Fi, WiMAX, 3G, 4G, LTE, and Bluetooth; and the Internet.

[0275] In embodiments, the controller includes a non-transient computer-readable medium having computer-executable instructions and data stored on it which, in response to execution by one or more processors of a computing device, causes the computing device to implement a processing method as described herein.

[0276] In some embodiments, the method for treating the biological surface region with cold atmospheric plasma includes generating the cold plasma between the plasma treatment device and the region. The treatment method may include measuring one or more treatment parameters with one or more sensors and determining a plasma dose from the treatment parameters. In some embodiments, the treatment method includes modulating one or more treatment parameters to adjust the plasma dose and stopping the cold atmospheric plasma.

[0277] In some embodiments, the process may include additional steps or may be carried out without all the steps illustrated in the flowchart. The process begins in the block and continues in the block where one or more sensors measure treatment parameters, for example, ambient and surface parameters. In some embodiments, before generating the plasma, the process includes placing at least one sensor on the biological surface at or near the treatment area. As described previously, the sensors may be functionally coupled to the controller and may provide sensor input to the controller for use in the block to determine plasma parameters necessary for effective treatment. In some embodiments, the plasma parameters are defined by default values, and the controller does not act until the plasma has been activated.In some embodiments, plasma parameters include a time-dependent discharge voltage, a time-dependent discharge current, a time-dependent plasma temperature, or a time-dependent near-region gas temperature. In some embodiments, sensor measurements are provided to a data storage system, which can aggregate the measurements with other sensor data. In some embodiments, a parameter engine communicates parameter information to the controller. The parameter engine determines a treatment dose based on the aggregated sensor inputs accumulated and stored in a data storage system, and further determines a set of plasma parameters that are provided to the controller.

[0278] A cosmetic formulation is applied to the treatment area. In some embodiments, the cosmetic formulation enhances the plasma treatment. In other embodiments, the cosmetic formulation protects the biological surface from harmful aspects of the plasma. A formulation engine can determine the formulation, which can receive input from the data storage system. In some embodiments, the formulation engine applies machine learning to optimize the components of the formulation for a given purpose, such as radical scavenging, UV absorption, electrical conductivity, thermal conductivity, etc.

[0279] The plasma treatment device applies cold atmospheric plasma to the biological surface at the treatment region. A post-plasma formulation is applied to the treatment region of the biological surface. The formulation can be determined by a formulation engine. In some embodiments, the post-plasma formulation may be the same as the initial formulation. In other embodiments, the post-plasma formulation may be different from the initial formulation. In some embodiments, the post-plasma formulation neutralizes ions and hydrates the biological surface. In other embodiments, the post-plasma formulation counteracts the possible oxidative effects of the plasma treatment by including antioxidant ingredients.

[0280] The treatment can be repeated. In some embodiments, the controller determines whether the treatment dose has been achieved. If the treatment dose has not been achieved, the controller can repeat the sensor measurements, determine new plasma parameters, and modulate the plasma to deliver an effective and safe dose of plasma-generated species. In other embodiments, the treatment is not repeated, and the process terminates.

[0281] The controller can determine plasma parameters in a group including a current supplied to the electrode, a driving frequency, a voltage waveform, a peak-to-peak voltage, an effective voltage, a plasma temperature, a gas temperature, an optical emission of the plasma, etc.

[0282] In some embodiments, the controller determines a uniformity indicator for the cold atmospheric plasma. As described previously, uniformity describes the spatial distribution of the plasma between the second side of the dielectric barrier and the biological surface, as well as whether a time-averaged current flux between the two surfaces is uniformly distributed over the treated region on the biological surface. In some embodiments, the controller sends control data to the plasma treatment device to modulate one or more plasma parameters in response to changes in the uniformity indicator. The controller can determine the uniformity indicator intermittently, based on sensor inputs provided to the controller.

[0283] As understood by a person with ordinary competence in the trade, a "data storage system" as described herein can be any suitable device configured to store data for access by a computing device. An example of a data storage system is a high-speed relational database management system (DBMS) that runs on one or more computing devices and is accessible over a high-speed network. However, other suitable storage techniques and / or devices capable of providing the stored data in response to queries may be used, and the device Computing can be accessed locally instead of being connected to a network, or it can be provided as a cloud service. Cloud storage systems can also include data stored in an organized manner on a computer-readable storage medium.

[0284] In general, the word "engine," as used here, refers to software and logic algorithms embedded in hardware or software instructions, which may be written in a programming language, such as C, C++, COBOL, JAVA™, PHP, Perl, H™L, CSS, JavaScript, VBScript, ASPX, Microsoft .NET™, and / or similar. An engine may be compiled into executable programs or written in interpreted programming languages. Software engines may be called from other engines or from themselves. In general, the engines described herein refer to logic modules that may be merged with other engines or may be divided into sub-engines.Engines can be stored on any type of computer-readable media or computer storage device and can be stored on one or more general-purpose computers and run by them, creating a specialized computer configured to provide the engine or its functionality.

[0285] Many embodiments of the technology described above can take the form of computer- or controller-executable instructions, including routines executed by a programmable computer or controller. Those skilled in the art will appreciate that the technology can be implemented on computer / controller systems other than those shown and described above. The technology can be incorporated into a specialized computer, an application-specific integrated circuit (ASIC), a controller, or a data processor that is specifically programmed, configured, or constructed to execute one or more of the computer-executable instructions described above. Of course, any logic or algorithm described herein can be implemented in software or hardware, or a combination of software and hardware.

[0286] From the foregoing, it will be understood that specific embodiments of the technology have been described herein for illustrative purposes, but that various modifications may be made without departing from the disclosure. Furthermore, although various advantages and features associated with embodiments have been described above in the context of those embodiments, other embodiments may also exhibit such advantages and / or features, and not all embodiments need necessarily exhibit such advantages and / or features to fall within the scope of the technology. Where processes are described, the processes may include more, fewer, or other steps.

[0287] Furthermore, the steps can be performed in any appropriate order. Therefore, the disclosure may encompass other embodiments not expressly shown or described herein.

[0288] For the purposes of this disclosure, lists of two or more items of the form, for example, "at least one of A, B and C" mean (A), (B), (C), (A and B), (A and C), (B and C), or (A, B and C), and further include all similar permutations where any other quantity of items is listed. TERMINOLOGY

[0289] This disclosure may refer to quantities and numbers. Unless otherwise specified, these quantities and numbers are not to be considered restrictive, but rather representative of the possible quantities or numbers associated with this disclosure. In this regard, this disclosure may also use the term "plurality" to refer to a quantity or number. In this regard, the term "plurality" is understood to mean any number that is more than one, for example, two, three, four, five, etc. The terms "about," "approximately," "near," etc., mean to within 5% of the stated value. For the purposes of this disclosure, the expression "at least one of A, B, and C," for example, means (A), (B), (C), (A and B), (A and C), (B and C), or (A, B, and C), including all other possible permutations when more than three items are listed.

[0290] The embodiments disclosed herein may use circuitry to implement the technologies and methodologies described herein, functionally connect two or more components, generate information, determine operating conditions, control an apparatus, device, or process, and / or the like. Any type of circuitry may be used. In one embodiment, the circuitry includes, among other things, one or more computing devices such as a processor (e.g., a microprocessor), a central processing unit (CPU), a digital signal processor (DSP), an application-specific integrated circuit (ASIC), a field-programmable gate array (FPGA), or the like, or any combination thereof, and may include discrete digital or analog circuit elements or electronics, or combinations thereof.

[0291] An embodiment includes one or more data stores that, for example, store instructions or data. Non-limiting examples of one or more data stores include: volatile memory (e.g., random access memory (RAM), dynamic random access memory (DRAM), or the like), non-volatile memory (e.g., read-only memory (ROM), electrically erasable and programmable read-only memory (EEPROM), compact disc with read-only memory (CD-ROM), or the like), persistent memory, or the like. Other non-limiting examples of one or more data stores include an erasable and programmable read-only memory (EPROM), a flash memory, or similar. One or more data stores can be connected, for example, to one or more computing devices by one or more instructions, data, or power buses.

[0292] In one embodiment, the circuitry includes a computer-readable media player or a memory location configured to accept a signal-carrying medium (for example, computer-readable memory storage, computer-readable recording storage, or the like). In one embodiment, a program to cause a device and / or system to perform any of the disclosed processes may be stored, for example, on computer-readable recording storage (CRMM), a signal-carrying medium, or the like.Non-limiting examples of signal-carrying media include recordable media such as any form of flash memory, magnetic tape, floppy disk, hard disk drive, compact disc (CD), digital video disc (DVD), Blu-Ray disc, digital tape, computer memory, or the like, and transmission media such as digital and / or analog communication media (e.g., fiber optic cable, waveguide, wired communication link, wireless communication link (e.g., transmitter, receiver, transceiver, transmission logic, receiving logic, etc.).Other non-limiting examples of signal carrier media include, but are not limited to, DVD-ROM, DVD-RAM, DVD+RW, DVD-RW, DVD-R, DVD+R, CD-ROM, Super Audio CD, CD-R, CD+R, CD+RW, CD-RW, compact video discs, super video discs, flash memory, magnetic tape, magneto-optical disc, MINIDISC, non-volatile memory card, EEPROM, optical disc, optical storage, RAM, ROM, system memory, web server, or similar.

[0293] The detailed description presented above in relation to the accompanying drawings, where similar numbers refer to similar elements, is intended to be a description of various embodiments of this disclosure and is not intended to represent the only embodiments. Each embodiment described in this disclosure is offered solely by way of example or illustration and should not be construed as being preferred or advantageous over other embodiments. The illustrative examples provided herein are not intended to be exhaustive or to limit the disclosure to the specific forms disclosed. Similarly, all the steps described herein may be interchangeable with other steps, or combinations of steps, to achieve the same or substantially similar result.In general, the embodiments disclosed here are not limiting, and the inventors contemplate that other embodiments within the scope of this disclosure may include structures and functionalities from more than one specific embodiment illustrated in the figures and described in the specification.

[0294] In the preceding description, specific details are presented to provide a thorough understanding of example embodiments of this disclosure. It will be apparent to those skilled in the art, however, that the embodiments disclosed herein can be implemented without incorporating all the specific details. In some cases, well-known process steps have not been described in detail so as not to unnecessarily obscure various aspects of this disclosure. Furthermore, it should be appreciated that the embodiments of this disclosure may employ any combination of features described herein.

[0295] This disclosure may include references to directions, such as "vertical," "horizontal," "front," "back," "left," "right," "top," and "bottom," etc. These references, and other similar references in this application, are intended to help describe and understand the particular embodiment (such as when the embodiment is positioned for use) and are not intended to limit this disclosure to those directions or locations.

[0296] The principles, representative embodiments, and modes of operation of this disclosure have been described in the preceding description. However, aspects of this disclosure that are intended to be protected should not be interpreted as being limited to the particular embodiments disclosed. Furthermore, the embodiments described herein should be considered illustrative rather than restrictive. It should be appreciated that variations and changes may be made by others, and equivalents employed, without departing from the spirit of this disclosure. Accordingly, it is expressly intended that all such variations, changes, and equivalents fall within the spirit and scope of this disclosure, as claimed. NON-EXHAUSTIVE METHODS

[0297] Although general features of the disclosure are described and shown, and specific features of the disclosure are presented in the claims, the following non-limiting embodiments relate to features, and combinations of features, that are explicitly contemplated as forming part of the disclosure. The following non-limiting embodiments contain elements that are modular and can be combined with each other in any number, order, or combination to form a new non-limiting embodiment, which can itself be further combined with other non-limiting embodiments.

[0298] Embodiment 1. Modular mask system configured for cosmetic analysis and treatment, the modular mask system comprising: a portable modular mask, comprising: a front portion attached to a rear portion which includes a grid system configured for cosmetic analysis, treatment cosmetic, or both; a template configured to accept and guide a printer device for the application of a cosmetic style to a portion of the individual's skin that is adjacent to the template; and a fixation site configured to accept and position a therapy device for the application of a cosmetic treatment to a portion of the individual's skin that is adjacent to the fixation site.

[0299] Embodiment 2. Modular mask system of embodiment 1 or any other embodiment, further comprising the printer device.

[0300] Embodiment 3. Modular mask system according to embodiment 1 or any other embodiment, further comprising the therapy device.

[0301] Embodiment 4. Modular mask system according to embodiment 1 or any other embodiment, further comprising control circuitry configured to control one or more analyses and / or cosmetic treatments.

[0302] Embodiment 5. Modular mask system according to embodiment 4 or any other embodiment, further comprising a computer device including circuitry configured to interact with the control circuitry for the coordination, observation or management of cosmetic analysis and processing by the computer device.

[0303] Embodiment 6. Modular mask system according to embodiment 5 or any other embodiment, wherein the computing device comprises a smartphone, tablet, laptop, desktop computer, smartwatch, portable computing device, or any combination thereof.

[0304] Embodiment 7. Modular mask system according to embodiment 1 or any other embodiment, wherein the wearable modular mask includes a lower detachment point at which an eye portion of the wearable modular mask is detachable from a mouth portion of the wearable modular mask.

[0305] Embodiment 8. Modular mask system according to embodiment 1 or any other embodiment, further comprising a portion of the scalp of the portable modular mask, wherein a rear portion of the scalp portion comprises a grid system configured for cosmetic analysis, cosmetic treatment, or both.

[0306] Embodiment 9. Modular mask system according to embodiment 8 or any other embodiment, wherein the wearable modular mask includes an upper detachment point at which the scalp portion of the wearable modular mask is detachable from an eye portion of the wearable modular mask.

[0307] Embodiment 10. Modular mask system according to any one of embodiments 1 to 9 or any other embodiment, wherein the system of modular mask includes circuitry configured for cosmetic analysis of a portion of the individual's skin based on a feature of the skin portion.

[0308] Embodiment 11. Modular mask system according to any one of embodiments 1 to 9 or any other embodiment, wherein the modular mask system includes circuitry configured to interact with a computer device which includes circuitry configured for cosmetic analysis of a portion of the individual's skin based on a feature of the skin portion.

[0309] Embodiment 12. Modular mask system according to any one of embodiments 1 to 11 or any other embodiment, wherein the grid system is configured for optical characterization of a portion of the individual's skin, electrical characterization of a portion of the individual's skin, light therapy, microcurrent therapy, radiofrequency (RF) heating therapy, cold plasma therapy, acoustic energy therapy, or any combination thereof.

[0310] Embodiment 13. Portable modular mask system according to any one of embodiments 1 to 12 or any other embodiment, wherein the printer device is configured for precise application of makeup to a portion of the individual's eyebrow.

[0311] Embodiment 14. A portable modular mask system according to any one of embodiments 1 to 13 or any other embodiment, further comprising an orifice configured to accept at least a portion of a smartphone lens for smartphone-facilitated imaging of at least a portion of the individual's face with placement of the portable modular mask on it via smartphone camera circuitry.

[0312] Embodiment 15. Portable modular mask system according to any one of embodiments 1 to 14 or any other embodiment, wherein the attachment site is positioned at a portion of the cheek of the portable modular mask.

[0313] Although illustrative embodiments have been shown and described, it will be appreciated that various changes can be made to them without departing from the spirit and scope of the invention.

Claims

Demands

1. Modular mask system (1) configured for cosmetic analysis and treatment, the modular mask system comprising: a portable modular mask (2), comprising: a front portion attached to a rear portion which includes a grid system (11) configured for cosmetic analysis, cosmetic treatment, or both; a template (3) configured to accept and guide a printer device (100) for the application of a cosmetic style to a portion of the individual's skin that is adjacent to the template; and an attachment site configured to accept and position a therapy device (100, 900) for the application of a cosmetic treatment to a portion of the individual's skin that is adjacent to the attachment site.

2. Modular mask system according to claim 1, further comprising the printer device (100).

3. Modular mask system according to claim 1, further comprising the therapy device (100, 900).

4. Modular mask system (1) according to claim 1, further comprising control circuitry configured to control one or more cosmetic analyses and / or treatments.

5. Modular mask system (1) according to claim 4, further comprising a computer device including circuitry configured to interact with the control circuitry for the coordination, observation or management of cosmetic analysis and processing by the computer device.

6. Modular mask system (1) according to claim 5, wherein the computing device comprises a smartphone, a tablet, a laptop, a desktop computer, a smartwatch, a portable computing device, or any combination thereof.

7. Modular mask system according to claim 1, wherein the wearable modular mask comprises a lower detachment point (4) at which an eye portion (9) of the modular mask portable is detachable from a portion of the mouth (10) of the portable modular mask.

8. Modular mask system according to claim 1, further comprising a scalp portion (13) of the wearable modular mask, wherein a rear portion of the scalp portion comprises a grid system (11) configured for cosmetic analysis, cosmetic treatment, or both.

9. Modular mask system according to claim 8, wherein the wearable modular mask (2) includes an upper detachment point at which the scalp portion (13) of the wearable modular mask is detachable from an eye portion (9) of the wearable modular mask.

10. Modular mask system (1) according to any one of claims 1 to 9, wherein the modular mask system comprises circuitry configured for cosmetic analysis of a portion of the individual's skin based on a feature of the skin portion.

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