Acidic sterilizing agent composition and cleaning sheet

Abstract

To provide an acidic sterilizing agent composition that does not influence on the quality of a material of a sterilized surface and has excellent sterilization power free from reduction of active ingredients, and to provide a cleaning sheet.SOLUTION: An acidic sterilizing agent composition contains: persulfuric acid or persulfate as an (A) component; an acid agent as a (B) component, containing at least one kind selected from the group consisting of inorganic acid, organic sulfonic acid and organic phosphonic acid; a surface active agent as a (C) component; and water as a (D) component (where, the (B) component does not contain sulfuric acid). A value of a mass ratio (A) / (C) of the (A) component to the (C) component is 0.5 or more and 200 or less. A cleaning sheet comprising a substrate sheet impregnated with the composition is also provided.SELECTED DRAWING: None

Description

[Technical field]

[0001] The present invention relates to a disinfectant composition and a cleaning sheet having excellent disinfecting properties against bacteria and viruses, antiviral properties, effective oxygen stability, and cleaning properties. Specifically, the present invention relates to a disinfectant composition and a cleaning sheet used for sanitary management of equipment and utensils in food factories, kitchens, medical facilities, etc., and more particularly to an acidic disinfectant composition and a cleaning sheet having excellent disinfecting properties against bacteria and fungi. [Background technology]

[0002] Disinfectants are used to reduce the risk of food poisoning and the spread of infection, and to maintain a good sanitary environment in medical facilities, food factories, kitchen facilities, etc. Disinfectants mainly composed of quaternary ammonium salts are generally used for disinfecting medical facilities, food factories, and kitchen facilities. Furthermore, in order to prevent the proliferation of microorganisms from dirt that adheres to and remains on the disinfected surface, disinfectant compositions that combine nonionic surfactants, anionic surfactants, and amphoteric surfactants are used for the purpose of providing cleaning properties.

[0003] However, disinfectant compositions containing quaternary ammonium salts as main components have the problem of causing corrosion or cracking when the material of the surface to be disinfected is plastic.Furthermore, quaternary ammonium salts may cause the problem of the emergence of cationic surfactant-resistant bacteria, and the remaining bacteria may be mixed into food or utensils, causing food spoilage and deterioration of the sanitary environment.

[0004] As a conventional disinfecting cleaning agent, Patent Document 1 describes a wet wiper containing a quaternary ammonium salt. Reference 2 describes a wet wiper containing a quaternary ammonium salt, butylcarbamic acid iodide propynyl, and polyaminopropyl biguanide. Patent Document 3 describes a virucidal composition containing a persulfate, a halide, sulfamic acid, a non-reducing organic acid, and an acidic phosphate. [Prior art documents] [Patent documents]

[0005] [Patent Document 1] JP 2016-022272 A [Patent Document 2] JP 2018-188368 A [Patent Document 3] Japanese Patent Publication No. 165309 / 1983 Summary of the Invention [Problem to be solved by the invention]

[0006] However, the wet wipers described in Patent Documents 1 and 2 have antibacterial properties against bacteria and mold, but when the material of the surface to be disinfected is plastic, they may be affected by corrosion or cracking, and there is a concern that bacteria resistant to cationic surfactants may appear. The virucidal composition described in Patent Document 3 is generally intended to be a powder, and it is troublesome to dissolve the powder and then immerse the wet wiper in it. In addition, when the composition is made into an aqueous solution, the active ingredient of the persulfate is reduced.

[0007] Accordingly, an object of the present invention is to provide an acidic disinfectant composition and a cleaning sheet that have excellent disinfecting power with little effect on the material of the surface to be disinfected and without reduction in the active ingredient. [Means for solving the problem]

[0008] In order to solve the above problems, the present inventors conducted intensive research and found that an acidic disinfectant composition comprising persulfuric acid or a persulfate salt as component (A), an acid agent containing at least one selected from the group consisting of inorganic acids, organic sulfonic acids, and organic phosphonic acids as component (B), a surfactant as component (C), and water as component (D), wherein the mass ratio (A) / (C) of component (A) to component (C) is 0.5 or more and 200 or less (provided that component (B) does not contain sulfuric acid), and a cleaning sheet comprising a base sheet impregnated with the same can solve the problems previously associated with the composition, and thus completed the present invention.

[0009] That is, the present invention is (1) An acidic disinfectant composition comprising, as a component (A), persulfuric acid or a persulfate salt, as a component (B), an acid agent including at least one selected from the group consisting of inorganic acids, organic sulfonic acids, and organic phosphonic acids, as a component (C), a surfactant, and as a component (D), water, in which the mass ratio (A) / (C) of the component (A) to the component (C) is 0.5 or more and 200 or less (provided that the component (B) does not contain sulfuric acid); (2) The acidic disinfectant composition according to (1), wherein the component (A) contains potassium hydrogen peroxomonosulfate; (3) The acidic disinfectant composition according to (1), wherein the component (C) contains at least one selected from the group consisting of amphoteric surfactants and anionic surfactants; (4) The acidic disinfectant composition according to (3), wherein the component (C) contains at least one selected from the group consisting of alkanesulfonates and polyoxyalkylene alkyl ether sulfates; (5) The acidic disinfectant composition according to (3), wherein the component (C) is an alkylamine oxide; (6) The acidic disinfectant composition according to (1), wherein the pH of the acidic disinfectant composition is 0.5 or more and 3 or less. (7) A cleaning sheet comprising a base sheet impregnated with the acidic disinfectant composition according to any one of (1) to (6). (8) A cleaning sheet in which the base sheet of (7) contains synthetic fibers and is impregnated with 100 parts by mass or more and 600 parts by mass or less of an acidic disinfectant per 100 parts by mass of the fibers constituting the base sheet. Effect of the Invention

[0010] The acidic disinfectant composition and cleaning sheet of the present invention have a low effect on the material of the surface to be disinfected and have an excellent disinfecting effect without any reduction in the active ingredient. DETAILED DESCRIPTION OF THE PREFERRED EMBODIMENTS

[0011] The present invention relates to an acidic disinfectant composition and a cleaning sheet which contain the above-mentioned components (A) to (D) as essential components. The acidic disinfectant composition and cleaning sheet of the present invention contain persulfuric acid or a persulfate as component (A), which mainly contributes to the disinfecting effect.

[0012] As the component (A), any persulfate or persulfate salt that has a disinfecting effect can be used. For example, persulfates include sodium peroxodisulfate, potassium peroxodisulfate, ammonium peroxodisulfate, sodium hydrogen peroxomonosulfate, potassium hydrogen peroxomonosulfate, and ammonium hydrogen peroxomonosulfate. For commercial reasons and from the viewpoint of disinfection, potassium hydrogen peroxomonosulfate is preferred as the persulfate. These oxidizing agents may be used alone or in combination.

[0013] Potassium hydrogen peroxomonosulfate is contained as part of a triple salt (2KHSO5·KHSO4·K2SO4) consisting of potassium hydrogen peroxomonosulfate, potassium hydrogen sulfate, and potassium sulfate. TM " is commercially available under the trade name. When component (A) contains potassium hydrogen peroxomonosulfate, it is preferable that the potassium hydrogen peroxomonosulfate be derived from a triple salt of potassium hydrogen peroxomonosulfate, potassium hydrogen sulfate, and potassium sulfate.

[0014] The concentration of oxidizing substances such as persulfuric acid can be measured by iodometric titration. <Test Method> An appropriate amount of test liquid was weighed out, 10 mL of 20% sulfuric acid and 10 mL of 25% potassium iodide solution were added, and titration was performed with 0.01 mol / L aqueous sodium thiosulfate solution. The point at which the solution became colorless for 30 seconds was set as the endpoint, and the available oxygen concentration was calculated from the amount of 0.01 mol / L aqueous sodium thiosulfate solution added up to the endpoint using the following formula (1). [Calculation formula] Available oxygen concentration (ppm) = (amount of 0.01 mol / L sodium thiosulfate solution dropped (mL) × 80.00) / amount of test solution (g) (1)

[0015] The acidic disinfecting composition of the present invention contains, as component (B), an acid agent containing at least one selected from the group consisting of inorganic acids, organic sulfonic acids, and organic phosphonic acids. This component (B) mainly contributes to the stability of component (A).

[0016] Examples of inorganic acids include sulfuric acid, hydrochloric acid, hydrobromic acid, hydroiodic acid, nitric acid, nitrous acid, thiocyanic acid, phosphoric acid, phosphorous acid, hypophosphorous acid, pyrophosphoric acid, tripolyphosphoric acid, tetrapolyphosphoric acid, metaphosphoric acid, pentapolyphosphoric acid, hexametaphosphoric acid, and condensed phosphoric acids such as ultraphosphoric acid.

[0017] Examples of organic phosphonic acids include methanesulfonic acid, ethanesulfonic acid, propanesulfonic acid, butanesulfonic acid, hexanesulfonic acid, xylenesulfonic acids such as m-xylenesulfonic acid, toluenesulfonic acids such as p-toluenesulfonic acid, cumenesulfonic acids such as p-cumenesulfonic acid, and benzenesulfonic acids such as methoxybenzenesulfonic acid.

[0018] Examples of organic phosphonic acids include 1-hydroxyethylidene-1,1-diphosphonic acid, methylene diphosphonic acid, 1,2-ethylene diphosphonic acid, 1-hydroxypropylidene-1,1-diphosphonic acid, 1-hydroxybutylidene-1,1-diphosphonic acid, and 2-phosphonobutane-1,2,4-tricarboxylic acid.

[0019] From the viewpoints of effective oxygen stability, disinfecting properties, and wiping residue after use of the agent, sulfuric acid, hydrochloric acid, nitric acid, phosphoric acid, methanesulfonic acid, pyrophosphoric acid, metaphosphoric acid, m-xylenesulfonic acid, p-toluenesulfonic acid, cumenesulfonic acid, 1-hydroxyethylidene-1,1-diphosphonic acid, and 2-phosphonobutane-1,2,4-tricarboxylic acid are preferred, sulfuric acid, hydrochloric acid, nitric acid, and phosphoric acid are more preferred, and sulfuric acid is even more preferred.

[0020] The acidic disinfectant composition of the present invention uses a surfactant as component (C). Any surfactant can be used as long as the effects of the present invention are achieved, and examples of such surfactants include amphoteric surfactants, anionic surfactants, cationic surfactants, and nonionic surfactants. In the acidic disinfectant composition of the present invention, amphoteric surfactants, anionic surfactants, and nonionic surfactants are preferred, and amphoteric surfactants and anionic surfactants are more preferred. Component (C) affects cleaning properties, drug penetration into nonwoven fabrics, wiping residue after use of the drug, material effects, etc.

[0021] When the component (C) is an amphoteric surfactant, examples of the surfactant include alkylaminoacetic acid betaine, alkylamidopropyl betaine, sulfobetaine, alkylamino (mono- or di-)propionate, imidazolinium betaine, alkylamine oxide, alkylaminoethyl glycine, alkyldi(aminoethyl)glycine, glycine n-(3-aminopropyl) C10-16 derivative, alkylpolyaminoethylglycine, alkylβ-alanine, alkyldiethanolamine, polyoxyalkylene alkylamine, diamine oxyethylene addition surfactant, etc. Among these, alkylamine oxide is preferred, alkyldimethylamine oxide having an alkyl group with 6 to 18 carbon atoms is more preferred, alkyldimethylamine oxide having an alkyl group with 8 to 14 carbon atoms is more preferred, and alkyldimethylamine oxide having an alkyl group with 10 carbon atoms (particularly decyl group) is even more preferred. The alkyl group may be branched or straight chain.

[0022] When component (C) is an anionic surfactant, examples thereof include fatty acids, alkyl or alkenyl succinic acids, polyoxyalkylene alkyl or alkenyl ether carboxylic acids, alkylol sarcosines, alkyl or alkenyl sulfates, polyoxyalkylene alkyl ether sulfates, polyoxyalkylene alkenyl ether sulfates, amide ether sulfates, alkylbenzene sulfonic acids, olefin sulfonic acids, alkanesulfonic acids, alkyl diphenyl ether disulfonic acids, dialkyl sulfosuccinic acids, polyoxyalkylene alkyl ether sulfosuccinic acid half esters, acyltauric acids, alkyl monophosphates, alkyl triphosphates, polyoxyalkylene alkyl ether phosphates, dipolyoxyalkylene alkyl ether phosphates, tripolyoxyalkylene alkyl ether phosphates, tripolyoxyalkylene alkyl ether phosphates, and alkali metal and ammonium salts thereof. Among these, alkyl sulfates or their salts, polyoxyalkylene alkyl ether sulfates or their salts, and alkanesulfonic acids or their salts are preferred, and secondary alkanesulfonic acids or their salts, and polyoxyethylene alkyl ether sulfates or their salts are more preferred. An example is sodium secondary alkanesulfonate. These may be used alone or in combination of two or more.

[0023] The anionic surfactant is a compound in the form of a salt, and may be, for example, an alkali metal salt such as sodium or potassium; an alkaline earth metal salt such as magnesium; or an alkanolamine salt such as monoethanolammonium or diethanolammonium.

[0024] The alkyl group of the alkyl sulfate is preferably an alkyl group having 8 to 18 carbon atoms. Specific examples of the alkyl sulfate include sodium lauryl sulfate and sodium myristyl sulfate. The alkyl group of the alkyl ether sulfate is preferably an alkyl group having 10 to 18 carbon atoms. The alkyl ether sulfate has an oxyethylene group and / or an oxypropylene group, and the average repeat number n of the oxyethylene group is preferably 1 to 5, and the average repeat number m of the oxypropione group is preferably 0 to 1. Examples of the alkyl ether sulfate include sodium polyoxyethylene lauryl ether sulfate.

[0025] The alkane sulfonate to be used is preferably an alkane sulfonate having 14 to 18 carbon atoms, and specific examples thereof include sodium secondary alkane (C14 to 17) sulfonate and sodium hydroxyalkane (C14 to 18) sulfonate.

[0026] The alkyl group of the linear alkylbenzene sulfonate is preferably an alkyl group having a carbon number of 8 to 16. Specific examples of the linear alkylbenzene sulfonate include sodium laurylbenzene sulfonate and sodium tetradecylbenzene sulfonate.

[0027] The alkenyl group of the α-olefin sulfonate is preferably an alkyl group having a carbon number of 8 to 20. A specific example of the α-olefin sulfonate is Liporan LB-440 manufactured by Lion Corporation.

[0028] The alkyl group of the alkyl diphenyl ether sulfonate is preferably an alkyl group having a carbon number of 8 to 18. Specific examples of the alkyl diphenyl ether sulfonate include Pelex SS-H and Pelex SS-L manufactured by Kao Corporation.

[0029] The sulfosuccinate is an alkyl succinate having a sulfo group, and the number of carbon atoms in the alkyl group is preferably 6 to 18. Specific examples of the sulfosuccinate include dioctyl sodium sulfosuccinate, didecyl sodium sulfosuccinate, didodecyl sodium sulfosuccinate, and di-2-ethylhexyl sodium sulfosuccinate.

[0030] The alkyl group of the alkyl ether carboxylate is preferably an alkyl group having a carbon number of 8 to 18. The alkyl ether carboxylate has an oxyethylene group and / or an oxypropylene group, and the average repeat number n of the oxyethylene group is preferably 1 to 10, and the average repeat number m of the oxypropylene group is preferably 0 to 1.

[0031] When the (C) component is a cationic surfactant, examples thereof include alkyl(alkenyl)trimethylammonium salts, dialkyl(alkenyl)dimethylammonium salts, alkyl(alkenyl)quaternary ammonium salts, mono- or dialkyl(alkenyl)quaternary ammonium salts containing an ether group, an ester group, or an amide group, alkyl(alkenyl)pyridinium salts, alkyl(alkenyl)dimethylbenzylammonium salts, alkyl(alkenyl)isoquinolinium salts, dialkyl(alkenyl)morphonium salts, polyoxyethylene alkyl(alkenyl)amines, alkyl(alkenyl)amine salts, polyamine fatty acid derivatives, amyl alcohol fatty acid derivatives, benzalkonium chloride, benzethonium chloride, etc. Among these, alkyltrimethylammonium salts are preferred.

[0032] When component (C) is a nonionic surfactant, examples of the surfactant include polyoxyethylene alkyl ethers, polyoxyethylene alkenyl ethers, polyoxyethylene polyoxypropylene alkyl ethers (the addition form of ethylene oxide and propylene oxide may be either random or block), polyethylene glycol propylene oxide adducts, polypropylene glycol ethylene oxide adducts, glycerin fatty acid esters or their ethylene oxide adducts, sorbitan fatty acid esters, polyoxyethylene sorbitan fatty acid esters, alkyl polyglucosides, fatty acid monoethanolamides or their ethylene oxide adducts, fatty acid-N-methyl monoethanolamides or their ethylene oxide adducts, fatty acid diethanolamides (e.g., coconut oil fatty acid diethanolamide) or their ethylene oxide adducts, sucrose fatty acid esters, alkyl (poly)glycerin ethers, polyglycerin fatty acid esters, polyethylene glycol fatty acid esters, fatty acid methyl ester ethoxylates, and the like. Among these, polyoxyethylene alkyl ethers, polyoxyethylene alkenyl ethers, and polyoxyethylene polyoxypropylene alkyl ethers (the addition form of ethylene oxide and propylene oxide may be either random or block) are preferred, and polyoxyethylene alkyl ethers are more preferred.

[0033] The alkyl or alkenyl group of the polyoxyethylene alkyl ether, polyoxyethylene alkenyl ether, and polyoxyethylene polyoxypropylene alkyl ether preferably has a carbon number of 8 to 14. Furthermore, the polyoxyethylene alkyl ether, polyoxyethylene alkenyl ether, and polyoxyethylene polyoxypropylene alkyl ether have an oxyethylene group and / or an oxypropylene group, and the average repeat number n of the oxyethylene group is preferably 1 to 30, and the average repeat number m of the oxypropylene group is preferably 0 to 10.

[0034] The above components (A) to (C) may each be a single component, or a combination of multiple components.

[0035] The acidic disinfectant composition of the present invention contains water as component (D). As the water, tap water, soft water, pure water, RO water, ion-exchanged water, and distilled water can be used. As the tap water, for example, tap water in Arakawa-ku, Tokyo (pH=7.6, total alkalinity (calcium carbonate equivalent) 40.5 mg / L, German hardness 2.3° DH (including calcium hardness 1.7° DH and magnesium hardness 0.6° DH), chloride ion 21.9 mg / L, sodium and its compounds 15 mg / L, nitrate nitrogen and nitrite nitrogen 1.2 mg / L, fluorine and its compounds 0.1 mg / L, boron and its compounds 0.04 mg / L, total trihalomethane 0.016 mg / L, residual chlorine 0.4 mg / L, organic matter (total organic carbon) 0.7 mg / L) can be mentioned. The water (D) of the present invention constitutes the balance relative to the total amount of the above components (A) to (C), or the balance relative to the total amount of components (A) to (C) and other optional components.

[0036] The concentration of the (A) component in the acidic disinfectant composition is not particularly limited as long as the effects of the present invention are achieved. From the viewpoints of disinfecting properties, material effects, and available oxygen stability of the acidic disinfectant composition, the concentration is preferably 0.1 mass % or more and 5 mass % or less, more preferably 0.2 mass % or more and 2 mass % or less, and even more preferably 0.3 mass % or more and 1 mass % or less, based on the total amount of the acidic disinfectant composition. Potassium hydrogen peroxomonosulfate is contained in the triple salt (2KHSO5·KHSO4·K2SO4) consisting of potassium hydrogen peroxomonosulfate, potassium hydrogen sulfate, and potassium sulfate at a concentration of 42.8 to approximately 45 mass%.

[0037] The concentration of the (B) component in the acidic disinfectant composition is not particularly limited as long as the effects of the present invention are achieved. From the viewpoint of the disinfecting properties and material effects of the acidic disinfectant composition, the concentration is preferably from 0.01% by mass to 5% by mass, more preferably from 0.05% by mass to 2% by mass, and even more preferably from 0.1% by mass to 1% by mass, based on the total amount of the disinfectant composition.

[0038] The concentration of the (C) component in the acidic disinfectant composition is not particularly limited as long as the effects of the present invention are achieved. From the viewpoints of the cleaning properties of the acidic disinfectant composition and the drug penetration into nonwoven fabrics, the concentration is preferably from 0.001% by mass to 2% by mass, more preferably from 0.01% by mass to 1% by mass, and even more preferably from 0.02% by mass to 0.7% by mass, based on the total amount of the acidic disinfectant composition.

[0039] The mass ratio of the (A) component to the (C) component in the acidic disinfectant composition of the present invention, (A) / (C), is preferably 0.1 or more and 5000 or less, more preferably 0.2 or more and 1000 or less, further preferably 0.5 or more and 300 or less, and most preferably 1 or more and 100 or less. If the (A) / (C) value is less than 0.1, disinfection properties and stability may be insufficient, and if it is more than 5000, cleaning properties and penetration of the agent into the nonwoven fabric may be deteriorated.

[0040] The acidic disinfectant composition of the present invention may further contain, as necessary, a pH adjuster, a glycol solvent and / or a glycol ether solvent, a chelating agent, a dye, other disinfectants, an antifoaming agent, a fragrance, a corrosion inhibitor, a natural extract, a thickener, an enzyme, other salt components (table salt, Glauber's salt, etc.), and the like.

[0041] Examples of pH adjusters include lithium hydroxide, potassium hydroxide, sodium hydroxide, cerium hydroxide, calcium hydroxide, magnesium hydroxide, barium hydroxide, aluminum hydroxide, sodium carbonate, sodium metasilicate, sodium acetate, potassium phosphate, sodium phosphate, sodium hydrogen phosphate, N,N-dimethylethanolamine, N,N-dibutylethanolamine, N-(β-aminoethyl)ethanolamine, N-methylethanolamine, N-methyldiethanolamine, N-ethylethanolamine, N-ethyldiethanolamine, Nn-butyldiethanolamine, Examples of the alkalis include Nt-butylethanolamine, Nt-butyldiethanolamine, N-(β-aminoethyl)isopropanolamine, N,N-diethylisopropanolamine, 2-amino-2-hydroxymethyl-1,3-propanediol, aminomethylpropanol, tetrahydroxypropylethylenediamine, morpholine, N-methylmorpholine, N-ethylmorpholine, piperazine, hydroxyethylpiperazine, 2-methylpiperazine, trans-2,5-dimethylpiperazine, and cis-2,6-dimethylpiperazine, and acids other than component (B) (e.g., acetic acid). These may be used alone or in combination of two or more.

[0042] Examples of the glycol solvent include ethylene glycol, diethylene glycol, triethylene glycol, propylene glycol, dipropylene glycol, tripropylene glycol, isoprene glycol, 1,2-butylene glycol, 1,3-butylene glycol, etc. These may be used alone or in combination of two or more kinds.

[0043] Examples of glycol ether-based solvents include ethylene glycol monomethyl ether, ethylene glycol monoethyl ether, ethylene glycol monopropyl ether, ethylene glycol monobutyl ether, ethylene glycol monohexyl ether, ethylene glycol monophenyl ether, diethylene glycol monomethyl ether, diethylene glycol monoethyl ether, diethylene glycol monopropyl ether, diethylene glycol monobutyl ether, diethylene glycol monobenzyl ether, triethylene glycol monomethyl ether, triethylene glycol monoethyl ether, triethylene glycol monopropyl ether, triethylene glycol monobutyl ether, triethylene glycol monohexyl ether, triethylene glycol monophenyl ether, propylene glycol monomethyl ether, propylene glycol monoethyl ether, propylene glycol monopropyl ether, propylene glycol monobutyl ether, dipropylene glycol monomethyl ether, dipropylene glycol monoethyl ether, dipropylene glycol monopropyl ether, dipropylene glycol monobutyl ether, ethylene glycol dimethyl ether, diethylene glycol dimethyl ether, diethylene glycol methyl ethyl ether, propylene glycol methyl ethyl ether, dipropylene glycol methyl ethyl ether, etc. These may be used alone or in combination of two or more.

[0044] Examples of the chelating agent include ethylenediaminetetraacetic acid, nitrilotriacetic acid, methylglycine diacetic acid, hydroxyethylenediaminetriacetic acid, diethylenetriaminopentaacetic acid, triethylenetetraaminehexaacetic acid, hydroxyethyliminodiacetic acid, dihydroxyethylglycine, glutamic acid diacetic acid, aspartic acid diacetic acid, β-alanine diacetic acid, serine diacetic acid, and alkali metal salts thereof, etc. These may be used alone or in combination of two or more.

[0045] Examples of the dyes include natural dyes, synthetic dyes, and mixtures thereof. Examples of other disinfectants include sodium hypochlorite, potassium hypochlorite, sodium chlorite, potassium chlorite, sodium chlorate, potassium chlorate, sodium perchlorate, potassium perchlorate, chlorinated sodium isocyanurate, chlorinated potassium isocyanurate, ε-polylysine, poly-γ-glutamic acid, nisin, and the like. Examples of the defoamers include silicone-based defoamers, polyether-based defoamers, higher alcohol-based defoamers, and the like. Examples of the fragrances include natural fragrances, synthetic fragrances, and blends thereof. Examples of the corrosion inhibitors include polycarboxylic acids such as short-chain dicarboxylic or tricarboxylic acids, phosphoric acid esters, triazoles such as benzotriazole, tolyltriazole, or mercaptobenzothiazole, adipic acid, glutaric acid, succinic acid, silicates, and the like. Examples of natural extracts include natural extracts derived from plants such as Cannabaceae, Rubiaceae, Cruciferae, Gramineae, Ebenaceae, Asteraceae, Labiatae, Zingiberaceae, Theaceae, Solanaceae, Cupressaceae, Myrtaceae, Vitaceae, Legumes, Rutaceae, and Liliaceae, and natural extracts derived from animals such as lysozyme and milt protein extract. Examples of thickeners include carrageenan, xanthan gum, guar gum, locust bean gum, ghatti gum, karaya gum, and pectin. Examples of enzymes include lipase, alkaline amylase, amylase, cellulase, protease, and pullulanase.

[0046] The pH of the acidic disinfectant composition of the present invention is preferably 0.5 or more and 3 or less, more preferably 1 or more and 2.5 or less, from the viewpoint of the stability of the component (A).

[0047] In the disinfection method using the acidic disinfectant composition of the present invention, the above-mentioned acidic disinfectant composition may be used as a disinfectant liquid by applying it directly to the surface of the object to be disinfected, or the disinfectant liquid may be sprayed or discharged onto the object to be disinfected using a foaming cleaner (spray gun or foam pump) or the like, or the object to be disinfected may be immersed in the disinfectant liquid. Furthermore, the acidic disinfectant composition may be impregnated into a substrate sheet described below and used as a cleaning sheet.

[0048] (Base sheet) The cleaning sheet of the present invention includes a base sheet. The cleaning sheet of the present invention may be a single-layer sheet substantially consisting of only the base sheet, or may be a laminated sheet of two or more layers consisting of the base sheet and any sheet laminated thereto. In addition, the cleaning sheet may be laminated with base sheets made of different materials.

[0049] The base sheet may be any sheet capable of adequately retaining the acidic disinfectant composition impregnated therein.Specific examples of the base sheet include nonwoven fabrics, woven fabrics, mesh fabrics, and the like made of recycled fibers, synthetic fibers, natural fibers, or mixtures thereof.

[0050] From the viewpoint of making the base sheet hydrophilic and enabling an increase in the amount of the acidic disinfectant composition impregnated therein, and of exhibiting good virus removal properties, it is preferable that the base sheet is a sheet containing synthetic fibers, and the proportion of synthetic fibers relative to the total mass of the fibers constituting the base sheet is more preferably 10% by mass or more, even more preferably 50% by mass or more, and even more preferably more than 75% by mass. The amount of the acidic disinfectant composition impregnated into the base sheet can be in the range of 100 parts by mass or more and 600 parts by mass or less, preferably 150 parts by mass or more and 500 parts by mass or less, and more preferably 200 parts by mass or more and 450 parts by mass or less, per 100 parts by mass of the fibers constituting the base sheet.

[0051] Regenerated fibers are made by dissolving natural polymer compounds into a solution and then spinning the solution through a spinneret. Examples of natural polymer compounds include cellulose-based materials using cellulose materials such as wood and cotton, and protein-based materials using protein materials such as milk, corn, and peanuts. Examples of regenerated fibers produced using cellulosic materials include rayon, polynosic, cupra, and lyocell. Examples of synthetic fibers include polypropylene, polyester, polyethylene terephthalate, polystyrene, and acrylic, and examples of natural fibers include cotton and wool.

[0052] The cleaning sheet of the present invention not only exhibits excellent disinfecting properties, but also has excellent corrosion prevention properties for objects to be cleaned. Therefore, the present invention is not only used to clean various objects to be cleaned in the home to provide a hygienic environment, but is also useful for disinfection in a wide range of fields, including the medical field, food field, brewing field, and agricultural field. In particular, the present invention achieves both disinfecting properties and the effect of preventing corrosion of objects to be cleaned, which was a conventional problem, and is therefore suitable for maintaining a hygienic environment in the medical field and food field, where there are many opportunities to clean plastic and stainless steel surfaces.

[0053] The cleaning sheet of the present invention can be used in various applications, and is suitable for, for example, surface disinfection other than human skin surfaces, equipment disinfection, or for sterilization and virus removal in areas around water such as toilets, around beds, drains, etc. The cleaning sheet of the present invention can be formed in a form in which multiple sheets are laminated, in a form in which a long sheet is wound into a roll, or in a form in which a sheet is folded to an appropriate size. EXAMPLES

[0054] The present invention will be specifically described below with reference to examples and comparative examples. The components used in the formulation in the examples and comparative examples are shown below. In the following examples, "%" stands for mass % unless otherwise specified, and the numerical values ​​of the formulations in the examples and comparative examples in the tables stand for mass % of the pure content. The "balance" indicating the water content indicates the formulation amount adjusted so that the total amount of the aqueous disinfectant, which is the final preparation, is 100 mass %. The compounds used in the examples and comparative examples are shown below. In addition, when the notation of an alkyl group is, for example, represented as alkyl(C8-18), it represents a mixture having an alkyl group having 8 to 18 carbon atoms.

[0055] The components of the acidic disinfectant composition (hereinafter, abbreviated as disinfectant composition) used in the cleaning sheets of the Examples and Comparative Examples are shown in the following Tables 1 to 9. Regarding the base sheet, the proportion (mass%) of each component fiber relative to 100 mass% of the base sheet is also shown in Tables 1 to 9. The cleaning sheets were prepared by impregnating 350 to 450 parts by mass of the disinfectant composition per 100 parts by mass of a nonwoven base sheet containing various fibers in the ratios shown in the table, and storing the sheets in an airtight container for 24 hours. Each cleaning sheet was clamped in a vice with a force of 10 N cm for 10 minutes, and the solution squeezed out was used as the squeezed liquid. The cleaning sheet and / or the squeezed liquid were used to carry out the measurements and evaluations described below. The measurement results and evaluation results are shown in Tables 1 to 9.

[0056] Component (A) A-1: Potassium peroxysulfate (sulfate) (manufactured by LANXESS, product name "OXONE" (trademark) (double salt consisting of potassium hydrogen peroxymonosulfate, potassium hydrogen sulfate, and potassium sulfate)) A-2: Potassium peroxodisulfate A-3: Sodium peroxodisulfate A-4: Ammonium peroxodisulfate

[0057] (B) Component B-1: Sulfuric acid B-2: Hydrochloric acid B-3: Nitric acid B-4: Phosphoric acid B-5: Methanesulfonic acid B-6: Pyrophosphate B-7: Metaphosphoric acid B-8: m-Xylene sulfonic acid B-9: p-Toluenesulfonic acid B-10: 1-hydroxyethylidene-1,1-diphosphonic acid B-11: 2-phosphonobutane-1,2,4-tricarboxylic acid

[0058] (C) Component C-1: Octyldimethylamine oxide (manufactured by Global Amines, product name "GENAMINOX OC (trademark)") C-2: Decyl dimethylamine oxide (manufactured by Global Amines, product name "GENAMINOX K-10 (trademark)") C-3: Sodium secondary alkane (C14-17) sulfonate (Clariant, product name "HOSTAPUR SAS30SB (trademark)") C-4: Sodium polyoxyethylene alkyl ether sulfate (manufactured by Teika Corporation, product name: Teikapol NE-7030 (trademark)) C-5: Alkyl (C14-C18) trimethylammonium chloride (manufactured by Lion Specialty Chemicals, product name: Lipocard 16-29 (trademark)) C-6: Polyoxyalkylene alkyl (C9-C11) ether (manufactured by Oxalis Chemicals, product name: JCT Ethoxylate 91-6)

[0059] (D) Component D-1: Ion-exchanged water

[0060] The compositions of each Example were prepared by adding water (D), component, to a mixing tank so that the total weight of the composition was 100% by mass, and then blending components (A), (B), and (C) into the mixing tank and thoroughly mixing and stirring.

[0061] Examples 1 to 59, Comparative Examples 1 to 6 The disinfectant compositions shown in Tables 1 to 9 were prepared. Each disinfectant composition was used to measure disinfecting properties, metal and plastic corrosion prevention properties, rinsing properties, and storage stability. Tables 1 to 5 and 7 to 8 show the results of Examples 1 to 59, and Tables 6 and 9 show the results of Comparative Examples 1 to 6, respectively. It should be noted that Examples 1 to 14, 19, 21 to 31, 35 to 45, 52 to 54, and 56 to 59 are reference examples.

[0062] *1: pH measurement method A composite electrode for measuring pH (HORIBA; glass ground sleeve type) was connected to a pH meter (HORIBA; pH / ion meter F-23) and the power was turned on. A saturated potassium chloride aqueous solution (3.33 mol / L) was used as the internal solution of the pH electrode. Next, a 100 mL beaker was filled with pH 4.01 standard solution (phthalate standard solution), pH 6.86 (neutral phosphate standard solution), and pH 9.18 standard solution (borate standard solution), and the beaker was immersed in a thermostatic bath at 25°C for 30 minutes. The pH measurement electrode was immersed in the thermostatically adjusted standard solution for 3 minutes, and the calibration operation was performed in the order of pH 6.86 → pH 9.18 → pH 4.01. Each disinfectant composition was filled into a 100 mL beaker and adjusted to 25° C. in a thermostatic chamber. A pH measurement electrode was immersed in the thermostatically adjusted sample for 3 minutes to measure the pH of the composition.

[0063] *2: Evaluation test regarding usability Test Method: Ten sheets of each cleaning sheet (200mm x 250mm) shown in Tables 1 to 9 were used, and one sheet of nonwoven fabric soaked in the chemical solution was taken out and wiped over a clean stainless steel surface in an area of ​​approximately 30cm square, five times up and down and five times left and right, and the feel of use was confirmed by a sensory test in terms of foaming, stickiness, wateriness, stiffness, dampness, etc. Panelists were selected at random, with n=10 for each sample. Statistical processing was performed to analyze the evaluation results, and the item with the most evaluations was adopted as the evaluation result.

[0064] Evaluation criteria: Good: Not foamy, sticky, watery or stiff, with just the right amount of moisture for a pleasant feel. △: Slightly foamy, sticky, watery, or stiff, or lacking the appropriate amount of moisture. ×: Extremely foamy, sticky, watery or stiff, or barely moist and uncomfortable to use. The evaluation was made as △ or ◯, and the evaluation was made as practical.

[0065] *3: Bactericidal activity test The test strain used was Staphylococcus aureus (NBRC13276).

[0066] 3-1: Cultivation of strains The test strains were smeared on SCD agar medium (Nissui Pharmaceuticals) and cultured at 37°C for 24 hours. Afterwards, the colonies were scraped off and diluted in sterile phosphate-buffered saline to be used as bacterial suspensions.

[0067] 3-2: Preparation of sterilizing neutralizing solution 10 g of soy lecithin, 30 g of Tween 80, 1 g of L-histidine, and 20 g of sodium thiosulfate were dissolved in 1 L of distilled water by heating and cooled while stirring. Then, 9 mL of each solution was dispensed into test tubes with screw caps and sterilized under high pressure (121°C, 20 minutes) to obtain a sterilized neutralized solution.

[0068] 3-3: Bactericidal activity test Test Method: Each disinfectant composition was diluted with ion-exchanged water to 0.5% by mass to prepare a disinfectant cleaning solution (10 mL), and the final concentration was 1.5 to 5.0 × 10 8 0.1 mL of each bacterial suspension was added so that the concentration was 100% (CFU / mL), and the mixture was left in contact at 20°C for 1 minute to prepare the test solution. 1 mL of each test solution was added to the sterilized neutralizing solution and thoroughly stirred. The mixture was mixed and solidified on SCD agar medium, and then cultured at 37°C for 2 days. After culture, the viable bacteria count was measured, and the difference from the initial bacteria count was used to evaluate the sterilization ability according to the following criteria. Test solutions rated as △, ○, or ◎ were deemed to be practical.

[0069] Evaluation criteria: ◎: Log reduction of test bacteria is 6 or more ○: Log reduction of test bacteria is 4 or more and less than 6 △: Log reduction of the test bacteria is 2 or more and less than 4 ×: Log reduction of test bacteria is less than 2

[0070] *4: Bacteria sterilization test (spore-forming bacteria) Test Method: The test strain was smeared on SCD agar medium (Nissui Pharmaceuticals) and cultured at 37°C. After culture, sufficient spore formation was confirmed by microscopic observation. 10 mL of sterilized pure water was placed on the plate medium, and the colonies were scraped off to collect the suspension. The collected suspension was centrifuged three times at 10,000 rpm, 4°C, and 15 minutes. After centrifugation, an appropriate amount of sterilized pure water was added, and 2.0 x 10 8 ~9.0×10 8 The number of bacteria was adjusted to approximately CFU / mL, and the bacteria was heated in a water bath at 80°C for 15 minutes to prepare a spore-forming solution.

[0071] 0.1 mL of the test spore bacteria liquid was added to 10 mL of each squeezed liquid, and the mixture was left in contact at 20°C for 10 minutes, after which a sterile neutralizing solution was added and the mixture was thoroughly stirred. Clostridioides difficile ATCC9689 (10 8 CFU / mL level) was used. 1 mL of this was mixed and cultured on SCD agar medium to confirm the viable cell count and evaluate it according to the following criteria.

[0072] Evaluation criteria: 1 point: Log reduction of 3 or more of the test bacteria 2 points: log reduction of the test bacteria is 2 or more but less than 3 3 points: log reduction of the test bacteria is less than 2 The reduction in the number of bacteria for each of the above-mentioned bacterial species was evaluated using a score, the average score of the reduction in the number of bacteria was calculated, and the sterilizing ability was evaluated according to the following criteria. ◎: Average value is 1.0 or more and less than 1.5 points. ○: Average value is 1.5 points or more and less than 2.0 points. △: Average value is 2.0 points or more and less than 2.5 points. ×: Average value is 2.5 points or more. The items were judged as practical with △, ○, and ◎.

[0073] *5: Virus inactivation test (feline calicivirus) <Test Method> 0.9 mL of each disinfectant composition and 10 8 A virus test solution (virus test solution 1) was prepared by adding 0.1 mL of feline calicivirus solution (FCV F9 strain) adjusted to TCID50 / mL, and the solution was mixed in a mixer and allowed to react at 25°C for 1 minute. In addition, assuming organic soiling, 0.9 mL of each disinfectant composition and 10 8 An organic soil-containing virus test solution (virus test solution 2) was prepared by adding 0.1 mL of feline calicivirus solution (FCV F9 strain) containing 0.5% meat extract (Nacalai Tesque) adjusted to TCID50 / mL, mixing in a mixer, and allowing to react at 25°C for 1 minute.

[0074] After reacting for 1 minute as described above, virus test solutions 1 and 2 were diluted 7-fold with Dulbecco's modified Eagle's Medium (DMEM) supplemented with 2% fetal bovine serum (FBS) to stop the reaction. The solution from which the reaction was stopped was serially diluted 7-fold with DMEM medium, and each dilution was inoculated into feline kidney cells (CRFK), which were then cultured in a 1% FBS-supplemented DMEM medium at 37°C in a CO2 incubator for 4 days. After the culture, the cytopathic effect was observed, and the virus infectivity (TCID50 / mL) was calculated. The virus infectivity log reduction value was calculated from the initial infectivity of the control and the infectivity after the action of the test product, and the virus inactivation effect was evaluated according to the following criteria.

[0075] <Evaluation criteria> ◎: Log reduction in viral infectivity of 4 or more. ○: Log reduction in viral infectivity of 3 or more but less than 4. △: Log reduction in virus infectivity of 2 or more but less than 3. ×: log reduction of virus infectivity of less than 2. The items were judged as practical with △, ○, and ◎.

[0076] *6: Test to reduce wiping marks caused by cleaning sheets A 15 cm x 15 cm glass plate was prepared, and the surface of the glass plate was wiped five times up and down and five times left and right with each cleaning sheet shown in Tables 1 to 9. The glass plate was then dried at room temperature for two hours, and the residual wiping marks on the surface of the glass plate were visually evaluated.

[0077] Evaluation criteria: ◎: No noticeable residue left behind. ○: There is almost no noticeable residue left behind. △: The marks left behind from wiping are a little noticeable, but not to a problem level. ×: Wipe marks are noticeable. The items were judged as practical with △, ◯, and ◎.

[0078] *7: Evaluation test for corrosiveness of the object being wiped Test Method: A total of 18 panels (2 panels each of 9 types of resin and metal panels (vinyl chloride, ABS, polypropylene, polyethylene, acrylic, polycarbonate, silicone, Teflon (registered trademark), and stainless steel) cut to a size of 1 cm x 2.5 cm x 7.5 cm were immersed in 30 mL of each disinfectant composition and stored at 25°C for 48 hours. After that, each panel was rinsed with ion-exchanged water and dried at room temperature for 24 hours, and then the degree of corrosion was evaluated visually.

[0079] Evaluation criteria: ◎: No discoloration, deterioration, or cracks are observed on any of the panels. ○: Less than 20% of the panels show discoloration, deterioration, cracks, etc. △: Discoloration, deterioration, cracks, etc. are observed in 20% to less than 30% of the panels. ×: Discoloration, deterioration, cracks, etc. are observed in 30% or more of the panels.

[0080] *8: Evaluation test for uneven distribution of medicine on the base sheet Test Method: Nonwoven fabrics (200 mm x 250 mm x 300 sheets) made of various materials shown in Tables 1 to 9 were placed in a 3 L polypropylene bag, impregnated with 2 L of each disinfectant composition, and stored at room temperature for 24 hours. After that, the bag was cut in half lengthwise and visually observed to see whether the chemical solution had penetrated to the center.

[0081] Evaluation criteria: ◎: The solution is evenly soaked into the entire area. ○: The solution has soaked into almost the entire area. △: Some areas are not saturated. ×: There are many areas that have not soaked in. The items were judged as practical with △, ○, and ◎.

[0082] *9: Evaluation test for discoloration of nonwoven fabric Test Method: Ten cleaning sheets (200 mm×250 mm) of each type shown in Tables 1 to 9 were used and stored at 40° C. for one week, after which the appearance of the cleaning sheets was visually observed for any change. Evaluation criteria: ◎: No discoloration or deterioration has occurred. ○: Almost no slight discoloration or deterioration has occurred. △: There is some dark discoloration or severe deterioration, but it is not a problem level. ×: Overall dark discoloration and severe deterioration have occurred. The items were judged as practical with △, ○, and ◎.

[0083] *10: Effective oxygen stability test Test Method: Nonwoven fabrics (200 mm x 250 mm x 300 sheets) made of the PET material shown in Tables 1 to 9 were placed in 3 L bags made of PET and polyethylene with aluminum vapor deposition, impregnated with 2 L of each disinfectant composition, stored at room temperature for 24 hours, and then sealed by heat sealing. The remaining effective oxygen rate was measured after leaving the bag at 40°C for one month. <Test Method> An appropriate amount of test liquid was weighed out, 10 mL of 20% sulfuric acid and 10 mL of 25% potassium iodide solution were added, and titration was performed with 0.01 mol / L aqueous sodium thiosulfate solution. The point at which the solution became colorless for 30 seconds was set as the endpoint, and the available oxygen concentration was calculated from the amount of 0.01 mol / L aqueous sodium thiosulfate solution added up to the endpoint using the following formula (1). [Calculation formula] Available oxygen concentration (ppm) = (amount of 0.01 mol / L sodium thiosulfate solution dropped (mL) × 80.00) / amount of test solution (g) (1)

[0084] Evaluation criteria: ○: Available oxygen remaining rate is 80% or more △: Available oxygen remaining rate is 60% or more but less than 80% ×: Available oxygen remaining rate is less than 60% The evaluation was made as △ or ◯, and the evaluation was made as practical.

[0085] *11: Storage stability test Test Method: 100 g of each disinfectant composition was placed in a polypropylene container and allowed to stand at 0° C., 25° C., and 40° C. for one month, after which the appearance was observed.

[0086] Evaluation criteria: ○: No separation or turbidity observed, stable △: No overall separation, slight turbidity, but no problem in use ×: Separation or turbidity observed The evaluation was made as △ or ◯, and the evaluation was made as practical.

[0087] [Table 1]

[0088]

Table 2

[0089]

Table 3

[0090]

Table 4

[0091]

Table 5

[0092]

Table 6

[0093]

Table 7

[0094]

Table 8

[0095]

Table 9

Claims

1. (A) component, persulfuric acid or a persulfate salt; (B) an acid agent including at least one selected from the group consisting of inorganic acids, organic sulfonic acids, and organic phosphonic acids; (C) a surfactant as component; (D) Water as component and a mass ratio (A) / (C) of the component (A) to the component (C) is 0.5 or more and 200 or less (provided that the component (B) does not contain sulfuric acid).

2. The acidic disinfectant composition according to claim 1, wherein the component (A) contains potassium hydrogen peroxomonosulfate.

3. 2. The acidic disinfectant composition according to claim 1, wherein the component (C) contains at least one selected from the group consisting of amphoteric surfactants and anionic surfactants.

4. The acidic disinfectant composition according to claim 3, wherein the component (C) contains at least one selected from the group consisting of alkanesulfonates and polyoxyalkylene alkyl ether sulfates.

5. The acidic disinfectant composition according to claim 3, wherein component (C) is an alkylamine oxide.

6. The acidic disinfectant composition according to claim 1, wherein the pH of the acidic disinfectant composition is 0.5 or more and 3 or less.

7. A cleaning sheet comprising a base sheet impregnated with the acidic disinfectant composition according to any one of claims 1 to 6.

8. 8. The cleaning sheet according to claim 7, wherein the base sheet contains synthetic fibers and is impregnated with 100 parts by mass or more and 600 parts by mass or less of an acidic disinfectant per 100 parts by mass of fibers constituting the base sheet.

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