Dynamic tear lens

Abstract

To disclose a dynamic contact lens that is manufactured with a dynamic portion extending outward from a peripheral portion.SOLUTION: When worn on an eye, a dynamic portion 101 forms a tear lens for vision correction. The dynamic portion 101 can also be configured to provide a dynamic tear lens that exchanges light intensity with force exerted by an eyelid. The dynamic portion 101 can be configured to exhibit a conforming configuration and at least one non-conforming configuration, or can be configured to exhibit at least two non-conforming configurations. The dynamic contact lens 100 can be used for vision correction, such as correcting presbyopia.SELECTED DRAWING: Figure 1A

Description

Technical Field

[0001] The present disclosure relates to a dynamic contact lens having a dynamic portion that, when placed on the cornea, has a conforming configuration and at least one non-conforming configuration, or can have at least two non-conforming configurations. When worn on the eye, the dynamic portion forms a tear lens for vision correction. The dynamic portion can also be configured to provide a dynamic tear lens that changes the light intensity in response to forces applied to the dynamic contact lens by the eyelid and / or the movement of fixation. The contact lens can be used for vision correction, such as correcting presbyopia, slowing the progression of myopia, or correcting vision caused by an irregularly shaped cornea.

Background Art

[0002] Typical vision problems such as myopia (nearsightedness), hyperopia (farsightedness), and presbyopia (loss of accommodation followed by loss of near and intermediate vision) can be easily corrected using glasses. However, some people prefer contact lenses for vision correction for reasons such as an active lifestyle or aesthetic reasons.

[0003] Contact lens wearers who have become presbyopic with age require additional corrective lenses that enable all of near vision, intermediate vision, and distance vision. To address presbyopia, contact lens manufacturers have developed multifocal lenses that simultaneously focus light from various distances through several focal regions, and bifocal lenses that include two focal regions, for example, a central portion for correcting myopia and a peripheral portion for correcting hyperopia. The latter lenses move with respect to the optical axis of the eye to provide correction for both myopia and hyperopia depending on the angle of the line of sight.

[0004] The alternating vision type (translating) contact lens is configured to move on the corneal surface from 1 mm to 6 mm, and thus is significantly less stable than a standard contact lens that typically moves on the cornea from 0 mm to 1 mm. Since the alternating vision type lens is designed to move, during the blink of the upper eyelid, the alternating vision type lens moves downward on the cornea, and as a result, the lower end of the lens hits the lower eyelid margin with each blink movement. Since the cornea and the lower eyelid margin are highly sensitive to foreign objects, such repeated movements and contact with the eyelids cause significant discomfort to the user. In addition, since the openings of the Meibomian glands are present on the lower eyelid margin, the impact on the lower eyelid can result in repeated trauma and inflammation of these openings, which can lead to hyperkeratosis and in some cases dysfunction of the Meibomian glands. Summary of the Invention

[0005] According to the present invention, a dynamic contact lens includes: a dynamic portion including a dynamic rear surface and a dynamic front surface facing the dynamic rear surface; a peripheral portion including a peripheral rear surface, a peripheral front surface facing the peripheral rear surface, and a transition zone connecting the peripheral portion and the dynamic portion; wherein the dynamic portion includes a material having a Young's modulus in the range of 0.05 MPa to 10 MPa and a fabricated central SAG height of 10 μm to 300 μm.

[0006] According to the present invention, a dynamic contact lens includes: a peripheral portion and a dynamic portion connected to the peripheral portion, wherein the dynamic portion includes a conforming configuration configured to provide a first light intensity to an eye having a cornea; and at least one non-conforming configuration configured to provide a second light intensity to the eye, the second light intensity being different from the first light intensity.

[0007] According to the present invention, a dynamic contact lens includes: a peripheral portion including a peripheral rear surface and a peripheral front surface, the peripheral rear surface including a peripheral base curvature; and a dynamic portion including a dynamic rear surface and a dynamic front surface, wherein at least the dynamic rear surface bulges away from the peripheral base curvature toward the dynamic front surface.

[0008] According to the present invention, a dynamic contact lens includes: a dynamic part including a dynamic rear surface having a dynamic base curve; a peripheral part connected to the dynamic part and having a peripheral rear surface; and the peripheral rear surface includes a peripheral base curve; wherein in a first configuration, the dynamic base curve is substantially the same as the peripheral base curve, and in a second configuration, the dynamic base curve deviates from the peripheral base curve.

[0009] According to the present invention, a dynamic contact lens includes a dynamic part, where the dynamic part includes a dynamic rear surface; the dynamic rear surface includes a dynamic base curve; in a first configuration, the dynamic base curve is substantially the same as the corneal curvature; and in a second configuration, the dynamic base curve deviates from the corneal curvature.

[0010] According to the present invention, a dynamic contact lens includes: a peripheral part, where the peripheral part includes a peripheral rear surface, and the peripheral rear surface includes a peripheral base curve; and a dynamic part connected to the peripheral part, where the dynamic part includes a central thickness and a central SAG height with respect to the peripheral base curve; where the dynamic part is configured to exhibit a first configuration characterized by a first central clearance height with respect to the peripheral base curve, and a second configuration characterized by a second central clearance height with respect to the peripheral base curve, the first central clearance height and the second central clearance height are different; and the first configuration and the second configuration are metastable states.

[0011] According to the present invention, a dynamic contact lens includes a dynamic part having a rear surface, where the rear surface has a dynamic base curve; in a first configuration, the rear surface includes a first base curve; and in a second configuration, the rear surface includes a second base curve.

[0012] According to the present invention, a dynamic contact lens includes a dynamic part, where the dynamic part includes at least one first non-conforming configuration configured to provide a first light intensity to an eye having a cornea; and at least one second non-conforming configuration configured to provide a second light intensity to the eye, the second light intensity being different from the first light intensity; the contact lens includes at least one first mechanism configured to cause a change between the first non-conforming configuration and the at least one second non-conforming configuration; and at least one second mechanism configured to cause a change between the at least one second non-conforming configuration and the at least one first non-conforming configuration.

[0013] According to the present invention, a dynamic contact lens includes: a first rear surface, a first front surface facing the first rear surface, and a first portion including a first material, where the first rear surface has a first radius of curvature, and the first material has a first Young's modulus, the first portion; and a second portion connected to the first portion, the second portion including a second rear surface, a second front surface facing the second rear surface, and a second material, where the second rear surface has a second radius of curvature; and the second material has a second Young's modulus, the second portion; the first radius of curvature is smaller than the second radius of curvature; and each of the first Young's modulus and the second Young's modulus is independently in the range of 0.05 MPa to 10 MPa.

[0014] According to the present invention, a dynamic contact lens includes: a first rear surface, a first front surface facing the first rear surface, and a first portion including a first material, where the first material has a first Young's modulus, the first portion; and a peripheral portion connected to the first portion, the peripheral portion including a peripheral rear surface having a base curve, and a second material having a second Young's modulus, the peripheral portion, the first rear surface bulging forward from the base curve of the rear surface of the peripheral portion, and each of the first Young's modulus and the second Young's modulus is independently in the range of 0.05 MPa to 10 MPa.

[0015] According to the present invention, a method for correcting a patient's vision includes the step of applying a dynamic contact lens according to the present invention to the eye of a patient in need of corrected vision.

[0016] According to the present invention, a method for treating presbyopia includes the step of applying a dynamic contact lens according to the present invention to the presbyopic eye of a patient.

[0017] According to the present invention, a method for correcting a patient's vision includes the step of applying a dynamic contact lens according to the present invention to the eye of a patient in need of such treatment.

[0018] According to the present invention, a method for treating a patient's eye following eye treatment includes the step of applying a dynamic contact lens according to the present invention to the eye of a patient in need of such treatment.

[0019] According to the present invention, a method for treating a traumatic wound to the cornea of a patient's eye includes the step of applying a dynamic contact lens according to the present invention to the eye of a patient in need of such treatment.

[0020] According to the present invention, a method for protecting a patient's eye from a possible injury includes the step of applying a dynamic contact lens according to the present invention to the eye of a patient in need of such protection.

[0021] According to the present invention, a method for manufacturing a dynamic contact lens includes the step of shaping a material to provide a dynamic contact lens, the dynamic contact lens comprising: a peripheral portion including a peripheral rear surface and a peripheral front surface, the peripheral rear surface including a peripheral base curve; and a dynamic portion including a dynamic rear surface and a dynamic front surface, wherein at least the dynamic rear surface bulges away from the peripheral base curve towards the dynamic front surface.

[0022] According to the present invention, a method of manufacturing a dynamic contact lens includes a step of shaping a material to provide a dynamic contact lens, the dynamic contact lens including: a dynamic portion characterized by a dynamic base curve; and a peripheral portion connected to the dynamic portion, the peripheral portion including a peripheral base curve, the dynamic base curve being different from the peripheral base curve.

[0023] According to the present invention, the dynamic contact lens according to the present invention is applied to the cornea.

Brief Description of the Drawings

[0024] The figures described herein are for illustrative purposes only. The figures are not intended to limit the scope of the present disclosure.

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[0025] Reference is now made in detail to particular embodiments of the present disclosure. While particular embodiments of the present disclosure are described, it is to be understood that the embodiments of the present disclosure are not intended to be limited to the disclosed embodiments. In contrast, reference to embodiments of the present disclosure is intended to embrace alternatives, modifications, and equivalents as may be included within the spirit and scope of the embodiments of the present disclosure as defined by the appended claims.

DETAILED DESCRIPTION OF THE INVENTION

[0026] As used herein, "rearward" refers to a feature that faces the eye, and "forward" refers to a feature that faces away from the eye when worn by the patient. The rear surface of a dynamic contact lens or a portion thereof refers to the surface that is proximate to or faces the cornea during wear by the patient. The front surface of a dynamic contact lens or a portion thereof refers to the surface that is away from or faces away from the cornea when worn by the patient.

[0027] "Substantially" refers to ±10% of a numerical value such as a dimension.

[0028] "Substantially conforming to the surface of the cornea" refers to a configuration in which the rear surface of a portion of the dynamic contact lens is within 3 μm of the surface of the cornea. The gap between the rear portion of the dynamic contact lens and the cornea can contain tears.

[0029] As used herein, the "modulus" of a substance refers to the Young's modulus. The Young's modulus can be determined according to the method described, for example, by Jones et al., Optometry and Vision Science, 89, 10, 1466-1476, 2017.

[0030] The optical power of the cornea in diopters (D) can be related to the radius of curvature R by the formula D = (1.3375 - 1) / R, where 1.3375 corresponds to the refractive index of the aqueous humor and R corresponds to the radius of curvature of the front surface of the cornea. The curvature of the cornea is inversely proportional to the radius of curvature R, such that as the radius of curvature increases, the curvature of the cornea decreases, and as the radius of curvature decreases, the curvature of the cornea increases.

[0031] It is known that a rigid gas permeable (RGP) lens generates a tear lens, but the RGP lens does not have the performance to change its structure. Soft dynamic contact lenses typically conform to the corneal surface in a uniform manner, and the thin tear film under the lens is not used and is not sufficient to create light intensity. In the present invention, a dynamic tear lens system is used in combination with a soft contact lens material.

[0032] The dynamic contact lens provided by the present disclosure can be manufactured with a dynamic part that can transition between two or more configurations on the eye, where each of the two or more configurations provides a different light intensity. When the dynamic part or at least a portion of the dynamic part is in a configuration that does not conform to the cornea, a lens-shaped volume is formed between the front surface of the cornea and the rear surface of the dynamic part of the dynamic contact lens, which can be filled with tears to form a tear lens for vision correction. The dynamic contact lens can be configured to transition between a conforming configuration and one or more non-conforming configurations. The dynamic lens can be configured to transition between two or more non-conforming configurations.

[0033] The dynamic contact lens provided by the present disclosure can be manufactured with a dynamic part that can transition between two or more configurations on the eye, where each of the two or more configurations provides a different light intensity. When the dynamic part or at least a portion of the dynamic part is in a configuration that does not conform to the cornea, a lens-shaped volume is formed between the front surface of the cornea and the rear surface of the dynamic part of the dynamic contact lens, which can be filled with tears to form a tear lens for vision correction. In this case, at least two configurations are non-conforming to each other, and each has a tear lens that provides a different light intensity to the eye.

[0034] The tear lens is a liquid lens formed between the rear surface of the dynamic contact lens and the anterior corneal surface. The tear lens is connected to other optical surfaces in a system (such as the cornea and the dynamic contact lens) to form a new optical system. The quantitative relationship between the base curve of the dynamic contact lens and the strength of the tear lens can be shown by Equation (1): Refractive power of the tear lens = (336 / R Boz - 336 / K)(1) wherein, R BOZ is the radius of the posterior optical zone of the dynamic contact lens in mm units, and K is the radius of the anterior surface of the cornea in mm units. The base curve refers to the curvature of the posterior surface of the peripheral part of the dynamic contact lens and is substantially the same as the curvature of the anterior surface of the cornea when placed on the cornea.

[0035] The quantitative relationship between the actual posterior base curve of the dynamic contact lens and the tear lens can also be shown by Equation (2): F 1 = (n - 1) / R BOZ + (1 - n) / RC(2) wherein, Ft is the optical strength of the tear lens, n is the refractive index of the tear fluid (1.337 ± 0.001), RC is the radius of curvature of the cornea in mm units, and R BOZ is the radius of the posterior optical zone of the dynamic contact lens in mm units.

[0036] In the tear lens formed in a cylindrical shape, the quantitative relationship is calculated for each meridian.

[0037] A cross-sectional view of an example of a dynamic contact lens (100) provided by the present disclosure is shown in FIG. 1A. The lens includes a dynamic portion (101) that bulges away from the base curve of the peripheral portion (102) and / or bulges away from the base curve of the peripheral portion adjacent to the dynamic portion. This region of the peripheral portion can be referred to as the peripheral portion near the center adjacent to the dynamic portion. There is a base curve in the periphery near the center. In the manufactured and non-conforming configurations, the dynamic portion bulges away from the base curve of the peripheral portion near the center. (102) represents a different curvature and it should be understood that it can itself be formed from one or more curvatures. The dynamic portion (101) includes a dynamic front surface (103) and a dynamic rear surface (104). The dynamic rear surface (104) includes a curvature. The peripheral portion of the dynamic contact lens (102) includes a peripheral front surface (105), a peripheral rear surface (106), a peripheral edge (107), and a lens diameter (116). The peripheral portion (102) is connected to the dynamic portion (101). The dynamic portion (101) and the peripheral portion (102) are connected at an interface (108) also called a transition zone. The peripheral rear surface includes a cavity (109) that is filled with tears to provide a tear reservoir when placed on the cornea. The peripheral rear surface (106) includes a peripheral base curve. The extension of the peripheral base curve under the region of the dynamic portion (101) is indicated by a dashed line. The SAG (sagittal) height (110) is shown as the distance from the peripheral base curve to the rear surface of the lens. As used herein, the SAG height refers to the dimension of the manufactured dynamic lens and can be referred to as the manufactured SAG height. When applied to the cornea, the distance between the rear surface of the dynamic portion and the cornea is called the gap height. As disclosed herein, the gap height may be the same as the SAG height, but in many embodiments, the gap height is less than the manufactured SAG height. At some viewing angles, the gap height may be less than the manufactured SAG height, and at other viewing angles, the gap height may approach the manufactured SAG height. The central bulge includes a plurality of SAG heights depending on the radial distance from the center of the lens. In FIG. 1A, the maximum SAG height is at the center of the dynamic portion located on the central geometric axis of the lens (112). The SAG height decreases towards the periphery of the dynamic portion (115) forming the lens shape.In FIG. 1A, the optical region (111) is slightly larger than the diameter of the dynamic portion. The optical region refers to the region of the lens used for vision. The diameter of the dynamic portion may be larger than that of the optical region. In some embodiments, the diameter of the dynamic portion can be less than the diameter of the optical region. In some embodiments, the diameter of the dynamic portion can be similar to or the same as the diameter of the optical region.

[0038] As shown in FIG. 1A, the central SAG height (110) is defined as the distance between the peripheral posterior surface (106), which is configured to be disposed against the cornea at the center of the dynamic portion (104), and the posterior surface. The dynamic portion can be characterized by a plurality of SAG heights that vary according to the position relative to the central axis of the bulging dynamic portion. The SAG height is maximum at the center and decreases towards the periphery of the dynamic portion. The dynamic portion (101) includes a central thickness (112), and two examples of the radial arrow thicknesses are identified as (113a) and (113b). In FIG. 1A, it is shown that the diameter of the optical region (111) is slightly larger than the diameter (115) of the dynamic portion. The dynamic contact lens (100) has a diameter (116). As shown in FIG. 1A, the dynamic portion (101), the peripheral portion (102), and the optical region are co-aligned and arranged together around the central geometric axis of the dynamic contact lens.

[0039] FIG. 1B shows a dynamic contact lens similar to that shown in FIG. 1A, but without a cavity for the tear reservoir. The elements of FIG. 1B are defined as relating to FIG. 1A.

[0040] The dynamic contact lens provided by the present disclosure includes a peripheral portion having a peripheral rear surface and a peripheral front surface facing the peripheral rear surface; a dynamic portion; and a transition zone connecting the peripheral portion and the dynamic portion; wherein the dynamic portion can include a material having a Young's modulus within the range of 0.05 MPa to 50 MPa; and the dynamic portion is characterized by a profile that extends away from the peripheral front surface and away from the peripheral rear surface. The dynamic portion can be characterized by a manufactured SAG height within the range of 10 μm to 250 μm. The Young's modulus is, for example, within the range of 0.1 MPa to 20 MPa, 0.1 MPa to 3 MPa, 0.1 MPa to 2 MPa, or 0.1 MPa to 5 MPa. The dynamic portion can be characterized by a manufactured SAG height within the range of 10 μm to 100 μm. The dynamic portion can include a maximum thickness within the range of 20 μm to 600 μm, 50 μm to 500 μm, 100 μm to 400 μm, or 50 μm to 300 μm. The dynamic portion can include a central thickness within the range of 20 μm to 600 μm, 50 μm to 500 μm, 100 μm to 400 μm, or 50 μm to 300 μm. The dynamic portion is characterized by a substantially uniform thickness, a central thickness the same as the thickness at the transition zone, a central thickness greater than the thickness at the transition zone, or a central thickness less than the thickness at the transition zone. The peripheral portion can include an intermediate portion connected to the dynamic portion characterized by an intermediate radius of curvature; and a distal portion connected to the intermediate portion characterized by a distal radius of curvature, where the intermediate radius of curvature is smaller than the distal radius of curvature. The transition zone can include one or more features configured to facilitate the transition of the dynamic portion between two or more metastable configurations. The dynamic contact lens can include one or more cavities on the peripheral rear surface. The dynamic contact lens can include one or more protrusions on the peripheral front surface. The dynamic contact lens can include one or more grooves on the rear surface of the peripheral portion. The dynamic contact lens can include one or more surface openings. The dynamic contact lens can include one or more cavities on the peripheral rear surface, one or more protrusions on the peripheral front surface, one or more grooves on the rear surface, and / or one or more surface openings. The groove or channel can be connected to one or more surface openings.

[0041] The dynamic contact lens provided by the present disclosure can include a dynamic part including a dynamic rear surface and a dynamic front surface facing the dynamic rear surface; a peripheral part including a peripheral rear surface, a peripheral front surface facing the peripheral rear surface, and a transition zone connecting the peripheral part and the dynamic part; wherein the dynamic part includes a material having a Young's modulus in the range of 0.05 MPa to 10 MPa and a manufactured central SAG height of 10 μm to 300 μm.

[0042] The material can have a Young's modulus in the range of, for example, 0.05 MPa to 8 MPa, 0.1 MPa to 6 MPa, 0.1 MPa to 4 MPa, 0.1 MPa to 3 MPa, 0.1 MPa to 2 MPa, or 0.5 MPa to 1 MPa.

[0043] The central SAG height, such as the manufactured central SAG height, can be in the range of, for example, 20 μm to 300 μm, 50 μm to 300 μm, 10 μm to 200 μm, 10 μm to 100 μm, 50 μm to 250 μm, or 50 μm to 200 μm.

[0044] The dynamic contact lens can be configured to generate a tear lens to correct vision when applied to the cornea.

[0045] When the dynamic contact lens is applied to the cornea, the dynamic part can exhibit two or more metastable configurations, where the two or more metastable configurations are characterized by different gaps between the central dynamic rear surface and the cornea. The dynamic contact lens can be configured such that the dynamic part can transition between two or more metastable states by the pressure applied to the dynamic contact lens by the eyelid.

[0046] The dynamic part can have a diameter of, for example, 2.5 mm to 7 mm, 2.5 mm to 6.5 mm, 2.5 mm to 6.0 mm, 2.5 mm to 5 mm, or 2 mm to 4 mm.

[0047] The dynamic rear surface can have a radius of curvature of, for example, 3 mm to 7.5 mm, 3 mm to 7 mm, 3.5 mm to 6.5 mm, or 4 mm to 6 mm.

[0048] The dynamic back surface of the dynamic contact lens may have a substantially spherical curvature, or the dynamic front surface may have a substantially spherical curvature. Thus, in certain embodiments, the light intensity of the dynamic lens is derived from the tear lens rather than the material forming the lens.

[0049] The dynamic portion can be of substantially uniform thickness. For example, the dynamic portion can be of substantially uniform thickness of 20 μm to 300 μm, 20 μm to 250 μm, 50 μm to 200 μm, or 50 μm to 150 μm.

[0050] The dynamic portion can be of non-uniform thickness. For example, the dynamic portion having a non-uniform thickness can have a central thickness of 20 μm to 300 μmι, 20 μm to 250 μm, 50 μm to 200 μm, or 50 μm to 150 μm.

[0051] The transition zone can be configured to facilitate the flow of tears into the tear lens formed between the dynamic back surface and the cornea when the dynamic lens is applied to the eye.

[0052] For example, the transition zone can include grooves or channels that facilitate the ability of tears to enter and exit the tear lens defined by the dynamic portion.

[0053] One or more channels can be disposed on the back surface of the peripheral portion and can extend from the dynamic portion to the peripheral portion.

[0054] For example, each of the one or more channels can extend radially outward from the dynamic portion.

[0055] One or more channels can include, for example, 3 to 20 channels, 3 to 16 channels, 3 to 12 channels, 4 to 10 channels, or 4 to 8 channels.

[0056] Each of the one or more channels can have a width of, for example, 100 μm to 1000 μm, 100 μm to 800 μm, 100 μm to 600 μm, 200 μm to 600 μm, or 400 μm to 600 μm.

[0057] Each of the one or more channels may have a height / depth of, for example, 50 μm to 200 μm, 50 μm to 150 μm, or 100 μm to 200 μm.

[0058] Each of the one or more channels may have a length of, for example, 1 mm to 7 mm, 1 mm to 6 mm, 1 mm to 5 mm, 1 mm to 4 mm, 1 mm to 3 mm.

[0059] The groove or channel can also have a suitable cross-sectional profile for promoting the flow of tears.

[0060] At least one of the channels can be connected to one or more surface openings that extend through the peripheral front surface. The surface openings can be configured to fluidly connect the tear layer or the front surface of the lens to the channel or to the tear film between the peripheral rear surface of the lens and the cornea. For example, the channel can be connected to 1, 2, or 3 or more surface openings.

[0061] Each of the one or more surface openings can independently have a diameter of, for example, 200 μm to 600 μm, 300 μm to 500 μm. The surface openings can also have any suitable cross-sectional profile for promoting the flow of tears.

[0062] The transition zone can include features configured to enhance the flexibility of the dynamic part. Examples of features for enhancing the flexibility of the dynamic part, promoting the transition ability of the dynamic part between metastable configurations, and / or promoting the ability of the dynamic part to preserve the metastable configuration include smooth ends, reduced cross-sectional thickness, grooves, or any combination thereof.

[0063] For example, the dynamic contact lens provided by the present disclosure may include a dynamic portion having a diameter of 2.5 mm to 7 mm, a dynamic rear surface having a radius of curvature of 3 mm to 7.5 mm, a substantially uniform thickness with a central thickness of 20 μm to 300 μm, one or more channels extending radially outward from the dynamic portion toward the peripheral end of the lens, where the one or more channels are 3 to 20 channels, each channel having a width of 100 μm to 1,000 μm, a height / depth of 50 μm to 200 μm, and a length of 1 mm to 7 mm, and one or more surface openings connected to each of the one or more channels, the surface openings having a diameter of 200 μm to 600 μm.

[0064] As another example, the dynamic contact lens provided by the present disclosure may include a dynamic portion having a diameter of 2.5 mm to 7 mm, a dynamic rear surface having a radius of curvature of 3 mm to 7.5 mm, a substantially uniform thickness with a central thickness of 50 μm to 300 μm, one or more channels extending radially outward from the dynamic portion toward the peripheral end of the lens, where the one or more channels are 3 to 10 channels, each channel having a width of 400 μm to 600 μm, a height / depth of 50 μm to 150 μm, and a length of 1 mm to 5 mm, and one or more surface openings connected to each of the one or more channels, the surface openings having a diameter of 300 μm to 500 μm.

[0065] The dynamic contact lens provided by the present disclosure may include a dynamic portion, where the dynamic portion includes a conforming configuration configured to provide a first light intensity to an eye having a cornea; and at least one non-conforming configuration configured to provide a second light intensity to the eye, where the second light intensity is different from the first light intensity, the non-conforming configuration; at least one first feature configured to cause a change between the conforming configuration and the at least one non-conforming configuration; and at least one second mechanism configured to cause a change between the at least one non-conforming configuration and the conforming configuration.

[0066] The dynamic contact lens provided by the present disclosure can include a dynamic portion, where the dynamic portion includes a first non-conforming configuration configured to provide a first light intensity to an eye having a cornea; and at least one second non-conforming configuration configured to provide a second light intensity to the eye, where the second light intensity is different from the first light intensity, the second non-conforming configuration; at least one first feature configured to cause a change between the first non-conforming configuration and the at least one second non-conforming configuration; and at least one second mechanism configured to cause a change between the at least one non-conforming configuration and a conforming configuration.

[0067] When applied to the eye, the dynamic portion can assume a configuration in which the back surface of the dynamic portion conforms, or substantially conforms, to the front surface of the cornea. In the conforming configuration, it can be understood that a thin tear film exists between the back surface of the dynamic contact lens and the front surface of the cornea. For example, the tear film can have a thickness of 0.1 μm to 3 μm, a thickness of 0.5 μm to 2.5 μm, or a thickness of 1 μm to 2 μm. The dynamic contact lens can be designed such that in the conforming configuration, the tear film thickness between the dynamic portion and the cornea is greater than 3 μm and / or can vary across the dynamic portion to form the shape of the lens.

[0068] When applied to the eye, the dynamic portion can exhibit a first non-conforming configuration where the rear surface of the dynamic portion does not conform to the front surface of the cornea. For example, in the first non-conforming configuration, the central gap between the front surface of the cornea and the rear surface of the dynamic portion can be greater than 3μm, greater than 5μm, greater than 10μm, greater than 20μm, greater than 30μm, greater than 40μm, greater than 50μm, greater than 60μm, greater than 70μm, greater than 80μm, or greater than 100μm, etc. For example, in the first non-conforming configuration, the central gap between the front surface of the cornea and the rear surface of the dynamic portion can be within the range of 5μm to 100μm, 10μm to 90μm, 10um to 70μm, 10μm to 50μm, or 10μm to 30μm. The dynamic portion can exhibit a second conforming configuration where the central gap between the front surface of the cornea and the rear surface of the dynamic portion is greater than the central gap in the first non-conforming configuration and can be, for example, within the range of 10μm to 200μm, or 10μm to 100μm. The basic difference between the two configurations is that one configuration conforms to the cornea and the other does not, thus creating a change in the tear lens dimensions between the two non-conforming configurations, which should be understood to provide a change in light intensity when the dynamic lens is in either of the two metastable non-conforming configurations.

[0069] The dynamic lens is manufactured such that the curvature (101) is different from the curvature (102), so that the manufactured SAG height is small when no tear fluid flows under the dynamic portion and no mechanical force is applied to the lens. However, when tear fluid flows under the dynamic portion, as caused by, for example, a change in gaze or eyelid pressure, the manufactured SAG exhibits some or all of the manufactured SAG height, resulting in a change in the dimensions of the tear lens, thereby changing the light intensity of the dynamic portion. The manufactured SAG can be designed based on the desired change in light intensity.

[0070] The gap height of the tear lens can exhibit from 10% to 100% of the manufactured SAG height during fixation changes or upon eyelid pressure. The percent of the gap height that can be restored is at least partially determined by the flow of the tear fluid, the availability of the tear fluid flowing under the dynamic part, and structural features such as tear fluid reservoirs, channels, grooves, surface openings, transitional geometries, peripheral and end geometries, and / or other features such as material properties and surface properties that control and / or facilitate the flow of the tear fluid in different parts of the dynamic lens. In fact, other structural features of the dynamic lens, including for example thickness, material modulus, radius of curvature, and diameter, together with the manufactured SAG height, apply a restoring force to the dynamic part in the forward direction and away from the cornea to generate a pumping force, draw out the tear fluid under the dynamic part, and contribute to forming a tear lens in a metastable non-conforming configuration. This restoring force can be overcome by the application of eyelid pressure to the dynamic lens that moves the dynamic part in the rearward direction and towards the cornea to assume another metastable non-conforming or conforming configuration.

[0071] In the conforming configuration, the distance between the rear surface of the dynamic part and the cornea can be, for example, less than 3μm, less than 2μm, or less than 1μm.

[0072] The dynamic lens can be designed and manufactured such that the dynamic part does not conform to the cornea. In such embodiments, the dynamic part creates a gap height of 10μm or more beyond the cornea to generate a tear lens that provides light intensity. For example, an optical portion with a diameter of 3mm with a base curve of 6.2mm creates a gap height of 40μm with respect to the base curve around the center; or for example, an optical portion with a diameter of 5mm with a base curve (BC) of 6.4mm will create a gap height of 100μm with respect to the BC around the center. In the conforming configuration, the base curve of the rear surface of the dynamic part can be substantially the same as the base curve of the peripheral portion.

[0073] In another embodiment, the contact lens is designed such that the dynamic part is made of a low modulus material as disclosed herein, for example a material having a Young's modulus of from 0.05 MPa to 10 MPa, or from 0.1 MPa to 2 MPa, and is designed not to conform to the cornea. In such an embodiment, the dynamic lens projects beyond the corneal curvature so as to create a gap of 10 μm or more in order to create a tear lens. For example, an optical portion with a diameter of 3 mm and a BC of 6.2 mm creates a gap height of 40 μm with respect to the BC around the center; or for example, an optical portion with a diameter of 5 mm and a BC of 6.4 mm will create a gap height of 100 μm with respect to the peripheral BC. In a conforming configuration, the base curve on the back surface of the dynamic part can be substantially the same as the base curve of the peripheral part.

[0074] The conforming configuration represents a state of metastability. Metastability means that the configuration can be preserved as long as, or for the period until, a force is not applied to disrupt the metastable equilibrium.

[0075] The metastable conforming configuration can be preserved by the adhesive force between the back surface of the dynamic part and the front surface of the cornea. The metastable conforming configuration can be preserved by the mechanical mechanics of the dynamic contact lens. The metastable conforming configuration can be preserved by a combination of the adhesive force and the mechanical force of the lens.

[0076] The adhesive force can be mediated, for example, by the adhesive force in the tear fluid and capillary forces including the adhesive force between the tear film and the front surface of the cornea. The surface tension of the thin film of tear fluid between the back surface of the dynamic part and the cornea can result in the adhesion of the two surfaces. Since the tear fluid and the anterior eye surface are hydrophilic, the adhesive force is preferred when the back surface of the dynamic part is also hydrophilic. Conversely, if the dynamic back surface is hydrophobic, the adhesive force will be smaller.

[0077] The mechanical force can arise from the selection of the thickness of a particular region of the lens, the selection of the curvature of a particular region of the lens, and the incorporation of features that facilitate the manipulation of the lens by the eyelid.

[0078] In a conforming configuration, the adhesion can spread across the entire dynamic posterior surface or can spread across a portion of the dynamic posterior surface.

[0079] In a conforming configuration, the gap between the dynamic posterior surface and the cornea is substantially uniform across the diameter of the dynamic portion. The difference in the gap can be defined as the difference between the gap distance at the center of the dynamic portion and the gap distance at a radial distance away from the center. In a conforming configuration, the difference in the gap is small and minimal. In a conforming configuration, the difference in the gap is smaller than in a non-conforming configuration.

[0080] In a conforming configuration, the dynamic portion can be configured to provide a first light intensity to the eye. The first light intensity may be 0 (0D). The light intensity can be, for example, in the range of 0D to ±6D, 0D to ±4D, 0D to ±3D, 0D to ±2D, or 0D to ±1D.

[0081] The dynamic portion can have one or more metastable non-conforming configurations.

[0082] One or more non-conforming configurations can include a single non-conforming configuration, two or more separate non-conforming configurations, or a plurality of metastable non-conforming configurations, and the non-conforming configurations can be continuous or separate.

[0083] In a conforming configuration, the difference in the gap between the center of the dynamic portion and the posterior surface of the lens at the periphery of the dynamic portion towards the transition zone having a periphery, between the dynamic portion and the cornea, is smaller in the conforming configuration than in the non-conforming configuration.

[0084] In a non-conforming configuration, the dynamic portion is not attached to the cornea. The dynamic portion spreads over or bulges away from the surface of the cornea to provide a lens-shaped volume between the posterior surface of the dynamic portion and the cornea. The lens-shaped volume can be filled with tear fluid to form a tear lens.

[0085] When in the eye, a non-conforming configuration of the dynamic contact lens in combination with the tear lens provides a second light intensity to the eye, where the first light intensity (in the conforming configuration) and the second light intensity are not the same. The second light intensity in the non-conforming configuration may be greater than or less than the light intensity in the conforming configuration. For example, the second light intensity may be less than ±1D, ±2D, ±3D, ±4D, ±5D, or ±6D of the first light intensity. For example, the second light intensity may be 0.1D to 6D, 0.1D to 5D, 0.1D to 4D, 0.1D to 3D, 0.1D to 2D, 0.1D to 1D of the first light intensity. For example, the second light intensity may be -0.1D to -6D, -0.1D to -5D, -0.1D to -4D, -0.1D to -3D, -0.1D to -2D, -0.1D to -1D of the first light intensity.

[0086] In certain dynamic contact lenses, the first light intensity does not cause a change in the light intensity to the eye; and in certain dynamic contact lenses, the second light intensity does not cause a change in the light intensity to the eye.

[0087] In certain dynamic contact lenses, the conforming configuration causes a first change in the light intensity to the eye; and in at least one non-conforming configuration, in addition to the first change in the light intensity, a second change in the light intensity to the eye is caused.

[0088] In a single non-conforming configuration, the dynamic portion can exhibit a single configuration where the dynamic central portion is not attached to the cornea. The single non-conforming configuration can be metastable. The single non-conforming configuration can be substantially the same shape as the manufactured dynamic portion.

[0089] The non-conforming configuration can include two or more separate configurations. Each of the two or more separate non-conforming configurations can provide a different light intensity to the eye. The different light intensities are created by different light intensities of the tear lens formed by the dynamic portion. Each of the two or more separate configurations can be metastable.

[0090] A non-conforming configuration can include a plurality of configurations that can be separate or continuous. These separate or continuous configurations may be metastable or may not be stable. One or more of the plurality of separate or continuous configurations can be metastable. For example, a metastable configuration included within a plurality of continuous configurations can substantially include the shape of the manufactured dynamic part.

[0091] The non-conforming configuration is characterized by a central gap height relative to the base curve of the peripheral portion. The rear surface of the peripheral portion can be characterized by a single curvature and can be extrapolated to extend under the dynamic part of the dynamic contact lens as shown in FIGS. 1A and 1B. In a non-conforming configuration, the distance between the rear surface of the dynamic part and the peripheral base curve is the gap height relative to the peripheral base curve. The gap height can decrease radially from the center of the dynamic part towards the periphery of the dynamic part in a non-conforming configuration.

[0092] In certain designs, such as a minus tear lens, the manufactured SAG height and gap height increase and then decrease towards the transition zone between the peripheral portion and the dynamic part.

[0093] The front surface of the lens can have a multifocal structure so that, for example, when the dynamic part exhibits a non-conforming configuration to provide additional light intensity to the eye, the area around the dynamic part provides the same light intensity as the conforming configuration.

[0094] The entire dynamic lens configuration can be coupled to a multifocal lens design to provide the advantages of a multifocal lens, while on the other hand, under desirable conditions, such as for intermediate vision and near vision, further providing additional light intensity from the dynamic lens.

[0095] When placed in the eye, the peripheral portion can conform to the cornea, and the peripheral base curve can be substantially the same as the corneal curvature, and the gap height can be based on the front surface of the cornea.

[0096] In a non-conforming configuration, the central gap height of the dynamic part can be greater than the central gap height of the conforming configuration.

[0097] In a non-conforming configuration, the difference in gap height is greater than the difference in gap height of the conforming configuration.

[0098] The dynamic contact lens provided by the present disclosure can include one or more features configured to cause a change in the structure of the dynamic part.

[0099] One or more features can cause a change in the structure upon application of pressure to the feature by the eyelid. The mechanism for applying eyelid pressure can be passive, active, or a combination thereof. The passive mechanism may include, but is not essential to, a conscious action by the wearer of the dynamic contact lens. For example, the passive mechanism can include changing the gazing angle. The active mechanism can include a conscious action by the wearer of the dynamic contact lens to cause a transition from one configuration to another. An example of an active mechanism includes consciously blinking or consciously squinting to cause a transition from one configuration of the dynamic part to another configuration of the dynamic part. Conscious mechanisms can include repeated blinking or keeping the eyelids closed for a certain period of time.

[0100] The mechanism for causing a structural change can also be due to internal forces within the lens that can inflate the dynamic part once the capillary force is overcome. For example, in a lens manufactured with swelling, the swollen structure can represent a low-energy configuration. After the capillary force is reduced to release the conforming dynamic part, the physical structure of the dynamic contact lens acts as a force to inflate the dynamic part away from the cornea and assume the manufactured shape. The mechanism for causing a transition between the conforming and non-conforming states may not include capillary force. The mechanical force within the lens can cause a transition between the configurations of the dynamic part. Tears can flow into the volume between the back surface of the dynamic contact lens and the cornea to form a tear lens during or after the transition of the dynamic part between configurations such as from a conforming configuration to a non-conforming configuration. The mechanical force can result from the design choices of the design of the dynamic contact lens and the choice of materials forming different parts of the lens. For example, the design elements include the thickness, rigidity, and / or radius of curvature of different parts of the manufactured dynamic contact lens, and the arrangement of protrusions on the front surface of the dynamic contact lens. An example of a material property is the modulus of the material forming different parts of the dynamic contact lens.

[0101] At least one first mechanism and at least one second mechanism can be the same mechanism or different mechanisms including, for example, capillary force and / or internal mechanical force.

[0102] The dynamic contact lens provided by the present disclosure can include a central geometric axis.

[0103] The dynamic parts can be arranged at the center of the geometric axis, near the center of the central geometric axis, deviating from the geometric axis, or any combination thereof. For example, the dynamic parts can be centrosymmetric and centered on the geometric axis of the dynamic contact lens. The near-center dynamic parts can be arranged in contrast at a radial distance around the central geometric axis of the dynamic contact lens. The dynamic parts can also be positioned away from the center of the geometric axis.

[0104] In a conforming configuration, the dynamic portion can be configured to substantially conform to the cornea.

[0105] In a conforming configuration, the dynamic portion can be configured to adhere to the cornea. Adhesion to the cornea, in a conforming configuration, means that the dynamic portion exhibits a metastable configuration where the rear surface of the dynamic portion is separated from the front surface of the cornea by a thin layer of tears. Adhesion to the cornea can be temporary. The adhesion can be such as to establish a metastable equilibrium. The metastable equilibrium can be disrupted by the application of force.

[0106] The dynamic portion can adhere to the corneal surface by capillary forces.

[0107] The layer of liquid between two wetted surfaces can be called a capillary bridge. The capillary adhesion force between the two surfaces is caused by capillary action that draws the liquid out of the narrow gap. The capillary adhesion force that pulls the two surfaces towards each other can preserve the relative position of the two surfaces in an equilibrium state. For example, by disrupting the equilibrium state, such as by pulling the opposing surfaces apart, the capillary adhesion force can be reduced and the surfaces can be separated.

[0108] In a non - conforming configuration, the tear lens can be formed within the volume between the rear surface of the dynamic portion and the surface of the cornea. The tear lens can provide additional light intensity to the eye. The tears for filling the tear lens can originate from a tear reservoir as disclosed herein, from the tear film between dynamic contact lenses at the periphery of the dynamic contact lens, from the periphery of the dynamic contact lens near the conjunctiva, through surface openings extending through the thickness of the dynamic lens, or from any combination thereof. In a dynamic contact lens including a surface opening extending from the front surface to the rear surface of the dynamic contact lens, the tears can also originate from the tears on the front surface of the dynamic contact lens.

[0109] The dynamic part of the dynamic contact lens can be configured to provide different light intensities for at least two different depths of vision. The depth of vision can include, for example, near vision, intermediate vision, and far vision.

[0110] For example, the dynamic contact lens can be configured such that when applied to the cornea, the dynamic part provides a first visual acuity corrected in a conforming configuration and a second visual acuity corrected in at least one non-conforming configuration.

[0111] For example, the dynamic contact lens can be configured such that when applied to the cornea, the dynamic part provides an uncorrected first visual acuity in a conforming configuration and a second visual acuity corrected in at least one non-conforming configuration.

[0112] For example, the dynamic contact lens can be configured such that when applied to the cornea, the dynamic part provides a first visual acuity corrected in a conforming configuration and an uncorrected second visual acuity in at least one non-conforming configuration.

[0113] Each of the first visual acuity and the second visual acuity can independently include far vision, intermediate vision, or near vision. For example, the dynamic contact lens can be configured such that when applied to the cornea, the dynamic part provides an uncorrected first visual acuity in a conforming configuration and a second visual acuity corrected in at least one non-conforming configuration.

[0114] The mechanism for causing a structural change can include the operation of a tear reservoir.

[0115] The cavity can be formed on the back surface of the dynamic contact lens. The cavity can be disposed at the periphery of the lens and outside the optical region so as not to interfere with vision. The cavity can be compressible or non-compressible.

[0116] When applied to the eye, the cavity can be filled with tears to form a tear reservoir. The tear reservoir can be compressible or non-compressible. The dynamic contact lens can include a compressible tear reservoir, a non-compressible tear reservoir, or a combination thereof.

[0117] The tear reservoir can be compressible by the application of eyelid pressure. The eyelid pressure can be applied, for example, by a change in the angle of gaze of the eye, by a normal blink, by an intentional blink, by a sidelong glance, or by any combination thereof.

[0118] The tear reservoir can be compressible by a force in the range of, for example, a force of 0.1 gm to 10 gm, a force of 0.2 gm to 8 gm, a force of 0.5 gm to 6 gm, a force of 1 gm to 5 gm, or a force of 2 gm to 4 gm.

[0119] It may simply be required that the tear reservoir be partially compressible so as to be effective in causing a change in the structure of the dynamic part. For example, to cause a change in structure, an amount of tears may be placed in the tear film gap between the back of the dynamic part and the cornea. The amount of tears may be sufficient to widen the gap or otherwise weaken the capillary force and release capillary adhesion. Thereafter, upon transition of the dynamic part to a non-conforming configuration, the tears fill an expanding lens-shaped volume and at least some of the tears can be removed from the tear reservoir. Alternatively, or additionally, by applying eyelid pressure to the tear reservoir to provide one or more separate non-conforming configurations or one or more continuous non-conforming configurations, tears can be intermittently, continuously, or semi-continuously placed in the gap between the dynamic back surface and the cornea.

[0120] The tear reservoir may also be related to a mechanism for transitioning from a non-conforming configuration to a conforming configuration. The tear reservoir can be configured to expand when released from a fully compressed state or a partially compressed state. The expanding lens-shaped volume of the tear reservoir can remove tears from the tear film and the tear lens. The result of filling the tear reservoir can be to pull the rear surface of the dynamic part against the cornea to establish or restore a quasi-stable state of the conforming configuration.

[0121] One or more tear reservoirs can be configured to be compressed only when pressure is applied by the eyelid during a change in gaze. During a change in gaze, the pressure applied by the eyelid to the front surface of the cornea and / or the compressible tear reservoir can result in dynamic contact with the eyelid by the front surface. More force can be applied to the compressible tear reservoir by normal blinking, intentional blinking, and / or squinting, where squinting can be holding the eyes closed for a period of time and with a certain force.

[0122] Accordingly, at least one first mechanism, at least one second mechanism, or both at least one first mechanism and at least one second mechanism can include manipulation of the fluid within one or more tear reservoirs. The tear reservoir can be fluidly connected to the tear film by the tear film between the peripheral rear surface and the cornea, to the tear film, or to the tear lens between the posterior portion and the cornea.

[0123] The cavity can be configured such that tears are preferentially pushed under the dynamic part during compression and preferentially withdrawn from under the dynamic part of the dynamic contact lens during release. This can be done, for example, by an appropriate selection of the shape of the cavity / tear reservoir. For example, an appropriate shape can include a cross-sectional profile that narrows towards the dynamic part such as a wedge-shaped cavity / tear reservoir.

[0124] The dynamic contact lens can include one or more tear reservoirs.

[0125] A single tear reservoir can include a concentric cavity disposed at a radial distance from the central geometric axis of the dynamic contact lens. A single tear reservoir can include a cavity disposed only in a portion of the periphery. For example, a single tear reservoir can include an arcuate cavity that is in the half of the periphery of the dynamic contact lens. For example, the arcuate cavity can be disposed at a radial distance from the central geometric axis of the dynamic contact lens and configured to be worn such that when worn by a user, the arcuate tear reservoir is in the lower portion of the dynamic contact lens. A single tear reservoir can be configured such that the reservoir can interact with the eyelid. A plurality of annular reservoirs can be provided such that each reservoir can have, for example, a different inner diameter. The annular reservoir can further have compartments such that when pressure is applied to the reservoir, the tears preferentially move to the dynamic portion rather than within the annular reservoir.

[0126] The dynamic contact lens can include two or more tear reservoirs, such as a plurality of tear reservoirs. The tear reservoirs can be formed and disposed in the periphery such that they interact with one or both eyelids and are suitable for causing a transition between a conforming configuration and a non-conforming configuration. The tear reservoirs can be disposed symmetrically or asymmetrically around the dynamic portion. The tear reservoirs can be disposed outside the optical portion so as not to interfere with vision.

[0127] At least one first mechanism, at least one second mechanism, or both at least one first mechanism and at least one second mechanism can include a step of exchanging tears by compressing a dynamic part of the dynamic contact lens and / or by compressing a peripheral part when pressure is applied to the dynamic contact lens by the eyelid during a gaze change. The step of exchanging tears can include exchanging tears within and / or between a tear film between the rear surface of the dynamic part and the cornea, a tear film between the peripheral rear surface and the cornea, a tear lens, one or more tear reservoirs, tears at the periphery of the lens, tears on the front surface of the lens, or any combination thereof.

[0128] At least one first feature, at least one second feature, or both at least one first feature and at least one second feature can include a protrusion on the front surface of a dynamic contact lens configured to interact with the eyelid.

[0129] The dynamic part and one or more tear reservoirs can be adjacent. In this design, eyelid movement at the periphery of the tear lens can move the dynamic central part towards the cornea such that the dynamic part bulges forward. The dynamic central part can exhibit a conforming or non-conforming configuration when bulging forward. The dynamic central part can exhibit at least two different non-conforming configurations when bulging forward.

[0130] Similar features as described for tear reservoir use can be used without a tear reservoir. The dynamic contact lens may not have a cavity and a tear reservoir, and similar movement due to eyelid and / or eye gaze angle can cause a transition between structures, and the tear lens can exchange tears with, for example, the tear film.

[0131] The protrusion can be disposed on the front surface of the periphery of the dynamic contact lens outside the optical region so as not to interfere with vision.

[0132] The protrusion can be configured to provide frictional force during dynamic contact with the eyelid. The frictional force can move the dynamic contact lens over the eye or, for example, release it, thereby causing a transition from a conforming configuration to a non-conforming configuration by applying a compressive force to the dynamic part sufficient to reduce the adhesive capillary force in the conforming state. The protrusion can be arranged symmetrically or asymmetrically around the dynamic part. The protrusion can include one or more concentric ridges at various radial distances from the center of the dynamic contact lens. The protrusion can be separate features arranged symmetrically around the dynamic central part at an angle of, for example, 120°, 90°, 60°, 45°, or 30°. The protrusion can be arranged outside the optical region of the dynamic contact lens so as not to interfere with vision.

[0133] The protrusion is a thickened area on the front surface of the lens and is designed to generate mechanical force when there is dynamic contact between the protrusion and the eyelid. The dynamic contact lens can include one or more protrusions. The one or more protrusions can be arranged at a specific distance from the dynamic part, for example, from 0.5 mm to 5.5 mm, 1 mm to 5 mm, 1.5 mm to 4.5 mm, or 2 mm to 4 mm from the dynamic part. The protrusion can have dimensions within, for example, 0.5 mm to 3 mm, 1 mm to 3 mm, or 1 mm to 2 mm. The one or more protrusions can independently have a height from the front surface of the dynamic contact lens of, for example, 10 μm to 500 μm, 50 μm to 450 μm, 100 μm to 400 μm, or 150 μm to 350 μm. The one or more protrusions can independently have any suitable cross-sectional profile, such as oval, kidney-shaped, dome-shaped, or rectangular, and the sides can have different inclinations.

[0134] In an embodiment where the protrusion overlaps the cavity, the protrusion can be designed to be compressible. Compressible, in this context, means that in a configuration where the cavity is in a compressed state, the height of the protrusion on the front surface of the dynamic lens is less than that in the uncompressed state and the protrusion also moves towards the cornea. For example, the protrusion may substantially conform to the curvature of the front surface to provide a substantially smooth profile.

[0135] In an embodiment where the protrusion overlaps the cavity, the cross-sectional thickness over the overlap can be less than, equal to, or greater than the thickness of the adjacent peripheral portion.

[0136] One or more protrusions can include surface features that enhance friction, such as grooves, depressions, and ridges. The grooves, depressions, or ridges can have dimensions less than those of the protrusion. For example, the height or depth of the grooves, depressions, or ridges can be less than 100 μm, less than 75 μm, less than 50 μm, or less than 25 μm. The dimensions of one or more features for enhancing the friction between the eyelid and the dynamic lens can be selected to promote user comfort.

[0137] The position and height of one or more protrusions can be selected such that the movement of the eyelid relative to the protrusion can cause a change in the structure of the dynamic part of the dynamic contact lens. The mechanism by which the protrusion can cause a change in the structure can be due to a change in capillary force and / or a change in the internal force of the dynamic contact lens. The protrusion can be positioned such that the force of the eyelid on one or more protrusions during downward gazing causes a change in the structure of the dynamic part.

[0138] One or more protrusions can be an excessive cavity, such as a tear reservoir. One or more protrusions may not be excessive, or can be a partially excessive cavity, such as a tear reservoir.

[0139] Figures 23A - 23C show diagrams of a dynamic contact lens having a protrusion on the front surface. Figure 23A shows a cross-sectional view of a dynamic contact lens having a central dynamic portion (2301) and a protrusion (2302). The peripheral portions (2304 and 2305) of the dynamic contact lens are connected to the dynamic portion (2301) and are characterized by two different curvatures. The peripheral portion includes a portion having a first curvature (2304) between the dynamic portion (2301) and the curved interface (2303), and a portion having a second curvature (2305) between the interface (2303) and the end (2306) of the dynamic contact lens. Figure 23B shows a front view of a dynamic contact lens including the dynamic portion (2301), five (5) rectangular protrusions (2302) arranged contrastingly at an angle of 75° around the central dynamic portion (2301), and the curved interface (2303). Figure 23C is a rear view of a dynamic lens including the dynamic central portion (2301) and the curved interface (2303). The dynamic lens shown in Figures 23A - 23C does not include a cavity on the rear surface of the dynamic lens.

[0140] Figures 24A - 24C show diagrams of a dynamic contact lens having protrusions on the front surface associated with respective cavities on the rear surface. Figure 24A shows a side view of a dynamic contact lens having a central dynamic portion (2401) and protrusions (2402) on the front surface. The peripheral portions (2404 and 2405) of the dynamic contact lens are connected to the dynamic portion (2401) and are characterized by two different curvatures. The peripheral portion includes a portion having a first curvature (2404) between the dynamic portion (2401) and the curved interface (2403), and a portion having a second curvature (2405) between the curved interface (2403) and the end (2406) of the dynamic contact lens. Figure 24B shows a front view of a dynamic contact lens including the dynamic portion (2401), five (5) rectangular protrusions (2402) arranged contrastingly at an angle of 75° around the central dynamic portion (2401), and the curved interface (2403). Figure 24C shows a rear view of a dynamic lens including the dynamic central portion (2401), the peripheral portion (2404) having a first curvature, the peripheral portion (2405) having a second curvature, and the curved interface (2403). The dynamic lens shown in Figures 24A - 24C includes a cavity (2406) on the rear surface of the dynamic lens. The cavity (2406) on the rear surface can cooperate with and underlie respective protrusions (2402) on the front surface of the dynamic lens.

[0141] It should further be recognized that, for example following eyelid pressure, such cavities can be compressible or deformable even in the absence of overlapping protrusions. Such compressibility can be achieved by thinning the lens thickness over the cavity, increasing the dimensions of the cavity, changing its geometry, changing the general geometry of the lens, or changing the rigidity of the cavity region such as by using a material having a low modulus, and / or by reducing the thickness of the peripheral portion proximate to the cavity.

[0142] The dynamic tear lens can be fluidly connected to at least one surface opening to facilitate the ingress and egress of tear fluid in the space between the lens and the eye. The number of surface openings can be, for example, between 1 and 50 such as 1 - 20 or 3 - 10, and can have an inner diameter between 50μm and 600μm such as 100μm - 300μm.

[0143] The dynamic contact lens provided by the present disclosure can include an optical region, which refers to the region of the dynamic contact lens used for vision.

[0144] The dynamic portion overlaps at least a part of the optical region. The dimensions of the dynamic portion can be less than, substantially the same as, or greater than the dimensions of the optical region.

[0145] The dynamic contact lens provided by the present disclosure can include a peripheral portion connected to the dynamic portion, where the peripheral portion is configured to hold the dynamic contact lens on the cornea. The dynamic portion and the peripheral portion can be connected in a transition zone. The transition zone can be dimensioned to facilitate, control, stabilize, destabilize, or any combination thereof, the transition between a conforming configuration and / or a non-conforming configuration.

[0146] For example, the cross-sectional thickness in the transition zone between the peripheral portion and the dynamic portion can be thinner or thicker than the thickness of the adjacent peripheral portion and / or dynamic portion of the dynamic contact lens. For example, in the cross-sectional profile of the dynamic contact lens, the thickness can gradually increase from the peripheral end of the lens in the peripheral region towards the transition zone having the dynamic portion. The thickness of the dynamic portion can be substantially uniform and can be the same as, thinner than, or thicker than the thickness of the transition zone. The thickness of the dynamic portion can increase from the transition zone thickness towards the center of the dynamic portion. The thickness of the dynamic portion can decrease from the transition zone thickness towards the center of the dynamic portion.

[0147] The transition zone can be configured to promote the maintenance of a metastable structure, promote the transition between metastable structures, and / or control and / or facilitate the fluid exchange with the tear lens.

[0148] The dynamic contact lens can include a dynamic portion including a first material characterized by a first modulus; and a peripheral portion including a second material characterized by a second modulus.

[0149] The first material and the second material may include the same material, or the first material and the second material may include different materials.

[0150] The first modulus may be greater than the second modulus, the first modulus may be less than the second modulus, or the first modulus may be the same as the second modulus.

[0151] The dynamic portion and the peripheral portion may include a single material characterized by a single modulus. As can be understood, depending on the thickness of the dynamic lens at a radial distance from the center, the dynamic lens can be characterized by a stiffness that varies with the radial distance from the center.

[0152] The first modulus may be, for example, in the range of 0.05 MPa to 100 MPa; and the second modulus may be in the range of 0.05 MPa to 100 MPa.

[0153] The first modulus may be, for example, in the range of 0.1 MPa to 2 MPa; and the second modulus may be in the range of 0.1 MPa to 2 MPa.

[0154] For example, the first modulus and the second modulus can independently be, for example, in the ranges of 0.05 MPa to 10 MPa, 0.1 MPa to 8 MPa, 0.15 MPa to 6 MPa, 0.2 MPa to 4 MPa, 0.25 MPa to 3 MPa, 0.3 MPa to 2 MPa, 0.3 MPa to 1.5 MPa, 0.3 MPa to 1.0 MPa.

[0155] Each of the first substance, the second substance, or a single substance can independently include silicon, hydrogel, silicone hydrogel, or any combination thereof. Any suitable material used to manufacture a soft contact lens can be used. The dynamic part can be manufactured from a different substance than the static part, but a single base material can be used to manufacture the dynamic contact lens, however, specific regions can be treated or modified to impart desirable mechanical properties. For example, the peripheral part and the dynamic part can include the same base material, but specific regions can have a design with a higher or lower crosslink density, for example, to exhibit a metastable configuration and / or to facilitate the performance of the dynamic part that transitions between metastable configurations in response to the force applied to the dynamic contact lens by the eyelid.

[0156] The dynamic contact lens can include a back surface; and at least a portion of the back surface can include a substance, surface treatment, or a combination thereof selected to control the capillary force between at least a portion of the back surface and the tear fluid, between the cornea and the tear fluid, between the back surface and the cornea, or any combination thereof.

[0157] The substance and / or surface treatment can be selected to provide hydrophobicity, hydrophilicity, polarity, charge, or other attributes of the surface that can affect the capillary force. The properties of the back surface can be uniform or non-uniform. The surface properties of the back surface can be continuous or discontinuous.

[0158] Examples of suitable surface treatments include coating, plasma treatment, and infiltration treatment.

[0159] The substance itself can be selected to set the desired surface properties.

[0160] The characteristics of the back surface of the lens, including the peripheral portion and the dynamic portion, may be the same or may differ in one or more regions of the back surface. For example, the characteristics of a certain surface may desirably control the capillary adhesion of the back surface of the dynamic portion to the cornea, and the characteristics of different surfaces may desirably promote the exchange of tears, for example, in the region between the tear reservoir and the dynamic portion.

[0161] In a cross-sectional profile, the dynamic portion can include a back surface that includes a gap profile between the back surface and the cornea. The gap profile can be characterized by a gap difference, where the gap difference is the difference between the central gap height and the peripheral gap height. The gap profile includes a plurality of gap differences that decrease in radial distance from the center of the dynamic portion toward the outer peripheral transition zone having a peripheral portion. The maximum gap difference can be defined as the difference between the central gap height and the gap height at the outer periphery of the dynamic portion.

[0162] A conforming configuration can be characterized by a first maximum gap difference; a non-conforming configuration can be characterized by a second maximum gap difference; where the second maximum gap difference is greater than the first maximum gap difference.

[0163] The dynamic contact lens provided by the present disclosure can include a manufactured shape. The manufactured shape includes a dynamic portion that bulges away from the peripheral base curve of the peripheral portion from the back surface toward the front surface.

[0164] The dynamic contact lens may not have a manufactured dynamic portion that bulges forward. The dynamic portion can have, for example, a front surface that is substantially continuous with the front surface of the peripheral portion. The tear lens in such a configuration can be provided by making at least a part of the dynamic portion less than the thickness of the transition zone having a peripheral portion. Such a configuration can be useful for providing negative light intensity to the lens.

[0165] In at least one of the at least one non-conforming configuration, the dynamic contact lens can include a manufactured shape.

[0166] The dynamic contact lens can include a peripheral portion that includes a peripheral back surface, where the peripheral back surface includes a peripheral base curve, and a dynamic portion that includes a dynamic back surface, where the dynamic back surface includes a dynamic base curve.

[0167] In a conforming configuration, the dynamic base curve can be substantially the same as the peripheral base curve.

[0168] In a non-conforming configuration, the dynamic base curve can deviate from the peripheral base curve. For example, the curvature of the dynamic portion can be greater than the peripheral base curve.

[0169] The cornea can be characterized by a corneal curvature. The dynamic portion of the dynamic contact lens can include a dynamic back surface, where the dynamic back surface can be characterized by a dynamic base curve. In a conforming configuration, the dynamic base curve can be substantially the same as the corneal curvature. In a non-conforming configuration, the dynamic base curve can deviate from the corneal curvature.

[0170] The dynamic contact lens can include a peripheral portion that includes a peripheral back surface, where the peripheral back surface includes a peripheral base curve, and the dynamic portion can be characterized by a central SAG height relative to the peripheral base curve.

[0171] The dynamic portion can be characterized by a first central SAG height relative to the peripheral base curve and can exhibit a second configuration characterized by a second SAG height relative to the peripheral base curve, where the first central SAG height and the second central SAG height are different. The first central SAG height can be greater than the second central SAG height and can also be less than the second central SAG height.

[0172] The dynamic portion can be configured to exhibit a first configuration characterized by a first central clearance height relative to the peripheral base curve and a second configuration characterized by a second central clearance height relative to the peripheral base curve, where the first central clearance height and the second central clearance height are different. The first central clearance height can be greater than the second central clearance height and can also be less than the second central clearance height.

[0173] The dynamic contact lens provided by the present disclosure can include a peripheral portion including a peripheral rear surface and a peripheral front surface, where the peripheral rear surface includes a peripheral base curve, the peripheral portion; and a dynamic portion including a dynamic rear surface and a dynamic front surface, where at least the dynamic rear surface bulges away from the peripheral base curve toward the dynamic front surface, the dynamic portion.

[0174] The dynamic contact lens is a dynamic portion including a dynamic rear surface, where the dynamic rear surface can be characterized by a dynamic base curve, the dynamic portion; and a peripheral portion connected to the dynamic portion and having a peripheral rear surface, where the peripheral rear surface can be characterized by a peripheral base curve, the peripheral portion.

[0175] Here, in the first configuration, the dynamic base curve can be substantially the same as the peripheral base curve, and in the second configuration, the dynamic base curve can deviate from the peripheral base curve. In the second configuration, the dynamic base curve can be less than the peripheral base curve.

[0176] The dynamic contact lens can include a dynamic portion including a dynamic rear surface, where the dynamic rear surface includes a dynamic base curve.

[0177] In the first configuration, the dynamic base curve may be substantially the same as the corneal curvature; and in the second configuration, the dynamic base curve may deviate from the corneal curvature. In the second configuration, the dynamic base curve can be less than the corneal curvature.

[0178] The dynamic contact lens can include a peripheral portion including a peripheral rear surface, where the peripheral rear surface can be characterized by a peripheral base curve; and can further include a dynamic portion connected to the peripheral portion, where the dynamic portion includes a central thickness, a central SAG height, and a gap height when applied to the cornea with respect to the peripheral base curve or a quasi-peripheral base curve adjacent to the dynamic portion.

[0179] The dynamic part can be configured to exhibit a first configuration characterized by a first central gap height with respect to the peripheral base curve, and can be configured to exhibit a second configuration characterized by a second central gap height with respect to the peripheral base curve.

[0180] The first central gap height and the second central gap height may be different.

[0181] The first configuration and the second configuration can be metastable.

[0182] The dynamic contact lens can include a dynamic part that includes a dynamic rear surface, where the rear surface includes a dynamic base curve.

[0183] In the first configuration, the rear surface of the dynamic part can be characterized by a first base curve; and in the second configuration, the rear surface of the dynamic part can be characterized by a second base curve.

[0184] The first configuration can be configured to provide a first light intensity to an eye having a cornea; and the second configuration can be configured to provide a second light intensity to the eye.

[0185] The first base curve can be substantially the same as the corneal curvature.

[0186] The dynamic contact lens includes at least one first feature, such as a protrusion, configured to cause a change between the first configuration and the second configuration; and at least one second mechanism configured to cause a change between the second configuration and the first configuration.

[0187] In the dynamic contact lens provided by the present disclosure, the dynamic part can be dome-shaped and can have a circular cross-section.

[0188] The dynamic contact lens provided by the present disclosure can include a dynamic part, where the manufactured dynamic part has a SAG height and a central thickness, and the central thickness is less than the SAG height; and the peripheral part is connected to the dynamic part, where the peripheral part is configured to hold the dynamic contact lens on the cornea. Referring to FIG. 1A, the SAG height is the distance between the extension of the curvature of the peripheral part across the dynamic part and the rear surface of the dynamic part on the central axis of the dynamic part.

[0189] The dynamic part can be characterized by a posterior and anterior curvature with respect to the SAG height, central thickness, radius thickness, rear surface profile, front surface profile, diameter, and spherical profile.

[0190] The manufactured SAG height (110 in FIG. 1A) of the dynamic part can be, for example, in the range of 5 μm to 300 μm, 10 μm to 250 μm, 15 μm to 200 μm, 20 μm to 150 μm, 30 μm to 125 μm, or 40 μm to 100 μm.

[0191] In a non-conforming configuration, the gap height (110 in FIG. 1A) can be, for example, in the range of 5 μm to 300 μm, 10 μm to 250 μm, 15 μm to 200 μm, 20 μm to 150 μm, 30 μm to 125 μm, 40 μm to 100 μm.

[0192] The central thickness (112 in FIG. 1A) of the dynamic contact lens can be, for example, in the range of 10 μm to 600 μm, 20 μm to 600 μm, 30 μm to 600 μm, 40 μm to 500 μm, 50 μm to 400 μm, 100 μm to 300 μm, 150 μm to 200 μm, 50 μm to 100 μm, 100 μm to 150 μm, 150 μm to 200 μm, 200 μm to 250 μm, or 250 μm to 300 μm.

[0193] The dynamic part (115 in FIG. 1A) can be characterized by a diameter in the range of, for example, 1 mm to 7 mm, 1.5 mm to 6 mm, 1.5 mm to 5 mm, 2 mm to 5 mm, 2 mm to 4 mm, or 2.5 mm to 3.5 mm.

[0194] The transition zone (108 in FIG. 1A) can have a thickness in the range of 10 μm to 600 μm, 20 μm to 600 μm, 30 μm to 600 μm, 40 μm to 500 μm, 50 μm to 400 μm, 100 μm to 300 μm, 150 μm to 200 μm, 50 μm to 100 μm, 100 μm to 150 μm, 150 μm to 200 μm, 200 μm to 250 μm, or 250 μm to 300 μm.

[0195] The moving part may have a spherical profile, and the radius of curvature of the rear and / or front surface can be, for example, 5 mm to 10 mm, 4 mm to 9 mm, 3 mm to 8 mm, 5 mm to 6 mm, 6 mm to 7 mm, 7 mm to 8 mm, 8 mm to 9 mm, 9 mm to 10 mm, 10 mm to 11 mm.

[0196] The moving part of the dynamic contact lens can include a rear surface and a front surface.

[0197] As manufactured, the shape of the moving part, including the rear and front surfaces, can include an outward bulge or dome, where the moving part extends from the rear to the front and away from the profile of the peripheral base curve.

[0198] In the dynamic contact lens provided by the present disclosure, the moving part can be configured to exhibit two or more configurations, each of which does not conform to the surface of the cornea. Thus, the dynamic contact lens can include a moving part, where the moving part includes at least one first non-conforming configuration configured to provide a first light intensity to an eye having a cornea; and at least one second non-conforming configuration configured to provide a second light intensity to the eye, the second light intensity being different from the first light intensity; at least one first physical characteristic configured to cause a change between the first non-conforming configuration and the at least one second non-conforming configuration, and at least one second physical characteristic configured to cause a change between the at least one second non-conforming configuration and the at least one first non-conforming configuration.

[0199] Many tear lenses can be in the range of, for example, 0.001 μL to 0.01 μL, 0.001 to 0.1 μL, 0.01 μL to 10 μL, 0.02 μL to 8 μL, 0.05 μL to 7 μL, 0.1 μL to 6 μL, 0.1 μL to 5 μL, 0.5 μL to 4 μL, or in the range of 1 μL to 3 μL.

[0200] The peripheral portion can have a diameter in the range of, for example, 8 mm to 17 mm, 8.5 mm to 16.5 mm, 9 mm to 16 mm, or 9.5 mm to 15.5 mm.

[0201] The peripheral portion can be characterized by a base curve, that is, the anterior curvature is, for example, in the range of 7 mm to 10 mm, 7.2 mm to 9.8 mm, 7.4 mm to 9.6 mm, 7.6 mm to 9.4 mm, 7.8 mm to 9.2 mm, or 8 mm to 9 mm.

[0202] In certain dynamic contact lenses provided by the present disclosure, the dynamic portion can be configured to facilitate a dynamic change between configurations when applied to the eye. For example, the dynamic portion can change its configuration during dynamic contact with the eyelid caused by, for example, a change in the gaze angle, by a normal blink, by an intentional blink, by keeping the eyelid closed, or by squeezing of the eyelid against the eye.

[0203] The posterior and anterior portions of the dynamic portion can independently have a spherical profile or a non-spherical profile. For example, the thickness of the dynamic portion can be substantially constant across the profile, can be thinner towards the center towards the transition zone, or can be thicker towards the center than the transition zone.

[0204] The dynamic contact lens can have a posterior surface characterized by a first radius of curvature; and a dynamic portion including a peripheral portion characterized by at least one second radius of curvature, where the first radius of curvature is smaller than the second radius of curvature. In other words, the dynamic portion extends forward from the peripheral base curve.

[0205] The dynamic portion of the dynamic contact lens includes thickness. The thickness of the dynamic portion can include a central thickness, where the central thickness refers to the thickness of the dynamic portion at the physical center of the dynamic portion, and can include a plurality of radial thicknesses extending to segments of the dynamic portion up to a transition zone of the dynamic portion having a peripheral portion from the center.

[0206] The thickness of the dynamic portion can be substantially uniform across the profile. In certain lenses, the thickness can vary or be non-uniform across the profile. For example, the central thickness can be greater than each of the plurality of radial thicknesses. The thickness of the dynamic portion can be radially symmetric about the central axis of the dynamic portion.

[0207] The thickness of the dynamic portion need not be uniform across the profile. The thickness can be greater or less towards the center compared to the periphery. The thickness of the dynamic portion can also vary across the profile.

[0208] The dynamic portion and the optical portion can be aligned with the optical axis of the dynamic contact lens. The optical axis of the dynamic contact lens refers to the central axis of the lens. In some embodiments, the dynamic portion is not aligned with the optical axis of the lens.

[0209] The optical region can be characterized by a diameter in the range of, for example, 1 mm to 8 mm, 2 mm to 7 mm, or 3 mm to 6 mm.

[0210] The dynamic portion and the peripheral portion of the dynamic contact lens provided by the present disclosure can include silicon, hydrogel, or silicone hydrogel.

[0211] The dynamic portion and the peripheral portion of the dynamic contact lens can include the same material. The dynamic portion and the peripheral portion can include different materials characterized by, for example, different physical and / or mechanical properties. The dynamic portion and the peripheral portion are characterized by materials having different moduli, and the portions can exhibit different rigidities.

[0212] The dynamic part and the peripheral part can also be characterized by rigidity. The rigidity of a cross-section is proportional to the material modulus which is the cube of the cross-section thickness. As can be recognized, when the peripheral part contains a single material, the rigidity of the cross-section increases as the thickness increases from the end of the peripheral part to the transition zone having the dynamic part.

[0213] The dynamic contact lens provided by the present disclosure can include a deformable dynamic part and a peripheral part connected to the deformable dynamic part. The dynamic part can be configured to deform to adapt to the depth of vision. The peripheral part can be configured to hold the dynamic contact lens on the cornea.

[0214] When applied to the eye, the lens-shaped volume between the rear surface of the dynamic part and the front surface of the cornea can be filled with tears to form a tear lens. In a dynamic contact lens, the dynamic part is configured to change shape according to the visual distance. The change in the configuration of the dynamic part provides a dynamic tear lens. The configuration of the dynamic part can change continuously or can exhibit distinct configurations. It should be recognized that a dynamic contact lens having a dynamic part can be manufactured to have a dome that extends outward (from the back to the front) from the curvature of the peripheral part. It should also be recognized that when the manufactured lens having an outwardly extending dome is worn by a user, the dome can extend outward smaller than when it is manufactured. In other words, when applied to the cornea, the dynamic contact lens can extend outward.

[0215] The first and second configurations correspond to different light intensities provided by the tear lens. The first configuration can be appropriate for distance vision and the second configuration can be appropriate for near vision. The first configuration can be appropriate for near vision and the second configuration can be appropriate for distance vision.

[0216] The purpose of the dynamic part is to facilitate changing the light intensity of the dynamic part according to the viewing distance of the eye. For example, in a first configuration suitable for distant vision, the dynamic part is arranged proximal to the anterior corneal surface, and for near vision, the dynamic part expands away from the cornea to form a tear lens.

[0217] In certain dynamic contact lenses, the light intensity of the dynamic part does not change even when the configuration of the dynamic part changes. In other words, the change in the light intensity of the dynamic part is predominantly or simply due to the change in the light intensity of the tear lens. For example, since the dynamic part exhibits different configurations, the thickness of the dynamic part and the relative cross-sectional profile of the posterior and anterior surfaces of the dynamic part do not change. The peripheral shape may not change much when the configuration of the dynamic part changes. The peripheral part can be configured to hold the dynamic contact lens on the cornea, hold the dynamic contact lens at the center of the optical region of the cornea, and minimize the transfer of the dynamic contact lens on the cornea. For example, the transfer of the lens on the cornea is less than ±1.5 mm, less than ±1.0 mm, or less than ±0.5 mm.

[0218] In different configurations, the central thickness and the radial thickness of the dynamic part may not change much. For example, the dynamic part can include a plurality of radial thicknesses, and the plurality of radial thicknesses in the first configuration are substantially the same as the corresponding radial thicknesses in the second configuration.

[0219] A uniform profile of the dynamic part with a changing configuration can also be considered in terms of curvature. In certain dynamic contact lenses, the dynamic part has no light intensity, and the posterior and anterior surfaces of the dynamic part have a spherical profile characterized by the same radius of curvature. The radius of curvature can be defined by the diameter of the dynamic part, the thickness of the peripheral part in the transition zone having the dynamic part, and the gap height.

[0220] In certain dynamic contact lenses, the dynamic portion can include a rear surface including a first radius of curvature, the dynamic portion can include a front surface including a second radius of curvature, and the ratio of the first radius of curvature to the second radius of curvature in a first configuration is the same as the ratio in at least one second configuration.

[0221] In certain dynamic contact lenses, the dynamic portion can be characterized by a plurality of radius thicknesses, each of the plurality of radius thicknesses being substantially the same across the entire range of gap heights accessible to the dynamic portion.

[0222] The configuration of the dynamic portion can be configured to change upon application of a force exerted on the dynamic contact lens by an eyelid. The force can be exerted on the periphery, an area of the periphery, and / or the dynamic portion.

[0223] The eyelid force can be applied by changing the gazing angle, such as staring forward for distance vision, or by looking downward for near vision. The eyelid force can be applied by a normal blink, or an intentional blink. An intentional blink can include keeping the eyelids closed for a period of time, squeezing the closed eyelids for a period of time, and / or repeating any of the foregoing a plurality of times.

[0224] The eyelid force can be used to transition the dynamic portion from one configuration to another, or to accelerate the transition from one configuration to another.

[0225] Since the change in the configuration of the dynamic portion is caused by the force exerted by the eyelid, the light intensity of the tear lens can change.

[0226] As manufactured, the dynamic portion of the dynamic contact lens extends forward so as to form a dome with respect to the expansion profile of the periphery of the dynamic contact lens.

[0227] In a configuration where the dynamic part is proximal to the front surface of the cornea, the dynamic part can be held in this metastable configuration by a combination of adhesive and cohesive capillary forces. As the thickness of the tear film layer decreases, the adhesive force between the rear surface of the dynamic part and the front surface of the cornea becomes greater than the adhesive force of the tear fluid, thereby causing the dynamic part to assume a metastable configuration in which the dynamic part substantially conforms to the surface of the cornea.

[0228] The transition between two or more configurations caused by eyelid forces, or of the dynamic part among such configurations, can be facilitated using various methods and features.

[0229] In certain methods, the capillary forces holding the dynamic part against the cornea can be disrupted by increasing the separation between the two surfaces. This can be done, for example, by pushing the tear fluid between the surfaces, thereby reducing the adhesive force and releasing the rear surface of the dynamic part. Depending on the structure, upon release, the dynamic part can assume a fully expanded dome-shaped configuration, and the tear fluid can be withdrawn from the transition zone between the peripheral rear surface and the cornea to fill the tear lens with tear fluid. Alternatively, or in combination, repeated blinking can be used to facilitate the movement of tear fluid to and / or from the tear lens. Blinking can include intentional blinking, whereby the user can achieve the desired vision correction without fully expanding the dynamic part.

[0230] In certain methods, the frictional force imparted to the periphery by the eyelid can be used to vary the configuration of the dynamic part and thus the light intensity of the tear lens. In such methods, the eyelid can capture the periphery and physically squeeze the dynamic contact lens towards the center in order to provide a force sufficient to overcome the capillary force holding the dynamic part against the cornea and thereby release the back surface of the dynamic part to provide a tear lens. Examples of physical lens features that can be used to facilitate the ability of the eyelid to impart mechanical force include protrusions such as ridges on the front surface of the periphery of the dynamic contact lens, thickness at the periphery, features that enhance friction between the end of the periphery and the conjunctiva, and the use of multiple curvatures at the periphery.

[0231] The dynamic part in the expanded configuration can be brought against the corneal surface by an intentional blink.

[0232] Cross-sectional views of the dynamic tear lens are shown in FIGS. 2A and 2B. FIG. 2A shows a dynamic tear lens configured for uncorrected farsightedness. FIG. 2B shows a dynamic tear lens configured for corrected nearsightedness.

[0233] FIGS. 2A and 2B include a dynamic contact lens (200) having a dynamic part (201) and a periphery (202). The periphery (202) includes a dynamic part (201) having an inner back surface (203) and an inner front surface (204), and a peripheral back surface (205) and a peripheral front surface (206). The dynamic contact lens (200) is positioned against the front surface (207) of the cornea (208). A tear film (209) is positioned between the back surface (203 / 205) of the dynamic contact lens (200) and the front surface (207) of the cornea (208). The tear fluid fills a tear reservoir (210). The eyelid (211) faces towards the periphery of the dynamic contact lens and does not compress the tear reservoir (see FIG. 2A). The direction of the visual field is aligned with the optical axis (212) to match uncorrected farsighted visual acuity.

[0234] In FIG. 2A, the dynamic part (201) conforms to the front surface of the cornea and / or is proximal to the front surface of the cornea so as to be suitable for uncorrected myopia. The tear reservoir (210) disposed on the peripheral rear surface (205) is filled with tears. The eyelid (211) is away from the tear reservoir (210).

[0235] In FIG. 2B, for corrected myopia adaptation, when the eye moves downward (212) (downward gaze) to focus on a nearby object, the eyelid (211) moves beyond the tear reservoir (219 in FIG. 2A) and compresses the reservoir to push tears towards the dynamic part. At the same time, the adhesion of the inner rear surface (203) to the anterior corneal surface (209) is broken down, as a result, the dynamic part (201) bulges outward away from the cornea (208). A tear lens (213) is formed between the inner rear surface (203) and the front surface (209) of the cornea (208), which serves to correct myopic vision. Other elements shown in FIG. 2B are as identified in FIG. 2A. FIGS. 2C and 2D show configurations of dynamic contact lenses similar to those of FIGS. 2A and 2B respectively, where the dynamic contact lens does not include a tear reservoir. Elements in FIGS. 2C and 2D are as defined in FIG. 2A.

[0236] FIGS. 3A - 3D show optical coherence tomography (OCT) images of cross - sections of an example of the dynamic contact lens provided by the present disclosure on the cornea. FIGS. 3A - 3D show the dynamic contact lens (300), the dynamically bulging part (301) on the outside, and the peripheral part (302). The dynamic contact lens is disposed on the cornea (306). FIG. 3A shows a dynamic contact lens without a gap and without bulging when the inner dynamic part is close to the corneal surface. FIGS. 3B - 3D show dynamic contact lenses having gap heights of 43 μm, 84 μm, and 105 μm respectively. The bulging of the inner dynamic part shown in FIGS. 3B - 3D generates a tear lens (304) for vision correction.

[0237] In addition to or as an alternative to the above - described method, the change in the configuration of the dynamic part can be facilitated by manipulating the flow of tears in and out of the tear reservoir.

[0238] The dynamic contact lens provided by the present disclosure can include a plurality of cavities disposed on the rear surface of the peripheral portion. So as not to interfere with vision, it would be desirable for the cavities to be outside the optical region of the lens.

[0239] A dynamic contact lens can be manufactured such that the rear surface of the peripheral portion includes one or more cavities.

[0240] One or more cavities can be configured to provide one or more tear reservoirs when the dynamic contact lens is applied to the cornea.

[0241] One or more cavities can be configured to provide one or more compressible tear reservoirs when the dynamic contact lens is applied to the cornea. The thickness of the peripheral portion between the cavity and the front surface of the peripheral portion may be thin enough so that the force applied by the eyelid can compress the cavity. The eyelid force can be applied by blinking, intentional blinking, or the movement of the eyelid moving over the cavity.

[0242] The cavities can be arranged and configured in any suitable manner to facilitate the transition of the dynamic part between two or more configurations.

[0243] For example, one or more cavities can be arranged symmetrically with respect to the dynamic part. One or more cavities can be arranged asymmetrically with respect to the dynamic part.

[0244] One or more cavities can include one or more concentric rings, one or more grooves, one or more wedge-shaped cavities, and / or one or more round cavities.

[0245] The cavities may be continuous around the dynamic part or can include a plurality of discrete cavities. The cavities may be elongated, such as rectangular or wedge-shaped, where the major axis points to the center of the lens. The discrete cavities can be fluidly connected to channels to facilitate the filling of tears and the flow between and / or between the cavities and the dynamic part.

[0246] For example, the separate cavities can have a width in the range of 0.1 mm to 5 mm, a length in the range of 0.1 mm to 5 mm, and a depth in the range of 10 μm to 200 μm.

[0247] The cavities can be continuous, semi - continuous, or separate. A continuous cavity refers to a single cavity disposed around the moving part. An example of a continuous cavity is a concentric ring or multiple concentric rings. The concentric rings can have any suitable cross - sectional shape. For example, the cross - sectional shape can be round, oval, square, rectangular, triangular, and / or angular. A number of concentric rings can be fluidly connected to one or more flow paths.

[0248] An example of a separated fluid cavity is a number of cavities disposed around the moving part of a dynamic contact lens. The number of cavities can be symmetrically disposed around the moving part, such as by being spaced 45° apart, or can be spaced around the moving part. For example, a group of cavities can be disposed around the moving part at intervals of, for example, 120°, 90°, 60°, 45°, or 30°, or at any other suitable interval. The separated cavities can have any suitable dimensions and cross - sectional shapes. For example, the separated cavities can have a hemispherical or triangular cross - sectional shape. The cavities can be elliptical, rectangular, cylindrical, annular, or any other suitable cross - sectional shape. The cavities can be symmetric or can be characterized by different lengths from the width.

[0249] One or more cavities can be arranged at a specific distance from the dynamic part, for example, from 0.5 mm to 5.5 mm, 1 mm to 5 mm, 1.5 mm to 4.5 mm, or 2 mm to 4 mm, etc. from the dynamic part. The cavity can have dimensions in the range of, for example, 0.5 mm to 3 mm, 1 mm to 3 mm, or 1 mm to 2 mm. One or more cavities can independently have a height from the front surface of the dynamic contact lens, for example, from 10 μm to 500 μm, 50 μm to 450 μm, 100 μm to 400 μm, or 150 μm to 350 μm. One or more cavities can independently have any suitable cross-sectional profile, such as elliptical, kidney-shaped, dome-shaped, or rectangular, and the sides can have different inclinations.

[0250] A semi - continuous cavity refers to a separate cavity that is fluidly connected by a channel formed on the rear surface of the dynamic contact lens. The channel can enable tears to flow between adjacent tear reservoirs.

[0251] When placed on the cornea, the cavity can be filled with tears to form a tear reservoir.

[0252] During compression due to eyelid movement or dynamic contact by the eyelid with changes in the gazing angle, tears can be pushed towards the dynamic part of the dynamic contact lens to disrupt the capillary force holding the dynamic part against the cornea and / or to increase the SAG height. The tear reservoir can provide a source of tears to fill the tear lens, thereby facilitating a faster response when changing from one configuration to another.

[0253] When the eyelid pressure is removed, the reservoir can expand, draw tears from the tear lens to fill the reservoir with tears, and effectively act to pull the dynamic part towards the cornea. The cavity and the resulting tear reservoir can serve to push and draw the tears entering and leaving the tear lens. The cavity can serve to modify the mechanical properties inside the dynamic contact lens to facilitate the transition of the dynamic part between metastable configurations.

[0254] Figures 4A - 4D show a dynamic contact lens provided by the present disclosure, where the tear reservoir includes a groove. The dynamic contact lens (400) shown in Figures 4A - 4D includes a dynamic portion (401), a peripheral portion (402), an inner rear surface (403), an inner front surface (404), a peripheral rear surface (405), and a peripheral front surface (406). A groove - shaped cavity on the peripheral rear surface of the lens provides a tear reservoir (407). As shown in Figure 4A with respect to uncorrected myopia, the rear surface of the dynamic portion has a curvature corresponding to the front surface of the cornea (not shown). As shown in Figure 4B, the pressure applied by the eyelid (not shown) to the grooved tear reservoir (407) pushes the tears towards the dynamic portion as indicated by the arrow (408). The cross - section of the tear reservoir (407) narrows towards the dynamic portion and deepens as it moves away from the dynamic portion. As shown in Figure 4C, the dynamic portion then deforms outwardly to form a downward bulge that forms a tear lens. At the same time, the tear reservoir compresses laterally with respect to the cornea. The tear lens can correct for near - vision. Figure 4D shows a bottom view of the lens including the dynamic portion (401), the concentric tear reservoir (407), and the peripheral portion (402).

[0255] Figures 5A and 5B show a cross - sectional view and a bottom view, respectively, of a dynamic contact lens having a separate cavity for holding tears. In the cross - sectional view shown in Figure 5A, the wedge - shaped cavity (507) is disposed around the deformable dynamic portion (501). In the bottom view shown in Figure 5B, the cavity (507) is symmetrically disposed around the peripheral portion (402) around the dynamic portion (501). The cavity can be a wedge formed with a narrower portion directed towards the dynamic portion of the dynamic contact lens.

[0256] FIG. 6 shows three (3) cross-sectional views of the dynamic contact lens provided by the present disclosure. The top view shows the manufactured lens immersed in water. The dynamic portion of the lens is centered on the geometric axis of the lens and bulges outwards away from the base curve of the peripheral portion. The central figure shows the dynamic contact lens applied to the cornea. The dynamic portion substantially conforms to the curvature of the cornea, and the base curve of the dynamic portion is substantially the same as the base curve of the peripheral portion. In the figure below where the dynamic contact lens is applied to the cornea, the dynamic portion assumes a second configuration in which the dynamic portion bulges outwards away from the cornea. The base curve of the dynamic portion is not the same as the base curve of the peripheral portion. A tear lens is formed between the rear surface of the dynamic portion and the front surface of the cornea. As a result of the tear lens, the dynamic contact lens in the figure below provides a light intensity of +3 diopters (+3D) as compared to the conforming configuration illustrated in the central figure. The optical portion of the eye is located between the dynamic portion and the peripheral end of the lens.

[0257] For example, based on calculations, for a lens having a particular diameter, a change from a certain non-conforming configuration to a second conforming configuration that provides +3 diopters to the eye requires a particular gap difference (cap height). For example, for a lens having an optical diameter of 2 mm, a change from a certain non-conforming configuration to a second conforming configuration that provides +3 diopters to the eye requires a 5 μm gap difference between the non-conforming and conforming configurations. Alternatively, as in the example shown in FIG. 7, for a lens having an optical diameter of 4 mm, the gap increases by 19 μm, or for a lens having an optical diameter of 5 mm, the gap increases by 30 μm, further providing a light intensity of +3 diopters (+3D). For these calculations, the anterior corneal base curve was R7.75 mm, and the front surface of the dynamic portion had a curvature of R7.25 mm when bulging forward.

[0258] FIG. 8 shows a cross-sectional view of a dynamic contact lens having a perimetric tear reservoir. The dynamic contact lens includes a dynamic portion (801) having a front surface (803) and a rear surface (804), a peripheral portion (802) having a front surface (805) and a rear surface (806), a peripheral end (807), a central portion (817), a central rear surface (818), and a central thickness (812) of the dynamic portion (801). The curvature of the rear surface (818) is the same as, or similar to, the base curve of the rear surface of the peripheral portion (806).

[0259] FIGS. 9A-9C show cross-sectional views of a dynamic contact lens provided by the present disclosure applied to a cornea (904). FIG. 9A shows a tear lens (902) under a dynamic portion (903) of the lens having a tear reservoir (901) with a SAG height of 104 μm (left) and a SAG height of 72 μm (right). In FIG. 9B, the dynamic portion (903) substantially conforms to the surface of the cornea (904), and the SAG height of the tear reservoir (901) increases to 144 μm. In FIG. 9C, after a pressure of a force from 0.1 gm to 10 gm is applied to the tear reservoir (901) shown in FIG. 9B, the dynamic portion (903) bulges away from the cornea (904) to reform a tear lens (902) having a SAG height of 76 μm, and the SAG height of the tear reservoir (901) is reduced to 120 μm.

[0260] In the dynamic contact lens shown in FIG. 10, a dynamic portion (1003) having a tear lens (1002) is disposed eccentrically about the central geometric axis of the dynamic contact lens. The central portion of the dynamic contact lens conforms to the surface of the cornea (1004).

[0261] Symmetrically arranging a cavity and a tear reservoir around the dynamic portion can change the function of the dynamic contact lens regardless of its orientation in the eye. By making the dynamic contact lens rotationally symmetric, the user's ability to wear the dynamic contact lens can be facilitated.

[0262] This push / pull action of the compressible cavity, to facilitate the transition of the dynamic part from one configuration to another, can serve as the only mechanism for changing the configuration and can also be increased by an intentional blink. For example, an intentional blink can help stabilize a configuration where the dynamic part is proximal to the corneal surface by, for example, squeezing out tears or thinning the tear layer between the dynamic part and the cornea.

[0263] The dynamic contact lens provided by the present disclosure can have a dynamic part but cannot include a mechanism for the transition between configurations. The dynamic contact lens can have a manufactured shape in which the dynamic part bulges forward from the base curve on the back surface of the peripheral portion. When applied to the cornea, the dynamic part forms a tear lens. However, unlike the dynamic tear lens, in this embodiment, the dynamic contact lens can generate a tear lens that does not change configuration due to changes in eyelid pressure on the lens. In certain embodiments, the dynamic part of the contact lens can be configured to resist deformation. In relation to a contact lens having a conforming configuration and at least one or more conforming configurations, or a dynamic part configured to exhibit a number of non-conforming configurations, a contact lens having a static tear lens exhibits a single non-conforming configuration when placed on the cornea. The periphery of a lens configured to have a contact lens, a dynamic part, and a static tear lens can be dimensioned with respect to a contact lens in which the dynamic part is configured to exhibit a number of configurations. A contact lens having a static tear lens would be suitable for the correction of vision of an irregular cornea, the treatment of astigmatism, and corneal wound healing. An example of a contact lens provided by the present disclosure configured to have a static tear lens is shown in FIG. 1B. FIG. 1B shows a cross-sectional view of a contact lens having a dynamic part and a peripheral portion. When applied to the cornea, a tear lens can be formed between the back surface of the dynamic part (1001) and the front surface of the cornea (not shown).

[0264] The dynamic contact lens provided by the present disclosure can include one or more surface apertures.

[0265] One or more surface apertures can be arranged at the periphery of the lens and outside the optical region so as not to interfere with vision.

[0266] One or more surface apertures can extend through the thickness of the periphery and fluidly connect the front and rear surfaces of the periphery. The surface apertures can facilitate the flow of tears into the tear film adjacent to the epithelium and, depending on the lens configuration, can facilitate the flow of tears in and out of the dynamic tear lens and / or can facilitate the exchange of tears along the epithelium to promote the health of the eye.

[0267] One or more surface apertures can be fluidly connected to one or more cavities. The surface apertures can enable tears to flow from the front surface of the dynamic contact lens into one or more cavities, which can facilitate the transition of the dynamic part between different configurations.

[0268] The surface aperture can be fluidly connected to a channel on the rear surface of the dynamic contact lens. The channel can extend from the peripheral region of the lens to the dynamic part. The channel can also fluidly connect a fluid cavity that may or may not be fluidly connected to the dynamic region of the dynamic contact lens.

[0269] Figures 33A - 41B show cross-sectional views of examples of dynamic contact lenses provided by the present disclosure.

[0270] Figures 33A and 33B show cross-sectional views of a dynamic contact lens having a central dynamic part (3301) and a cavity (3302) on the rear surface of the dynamic lens. The thickness of the dynamic part (3301) is substantially uniform. The profile of the dynamic lens is shown in a non-conforming configuration (Figure 33A) and a conforming configuration (Figure 33B). In the non-conforming configuration, the cavity is in a compressed state, and in the conforming configuration, the cavity is in a non-compressed state.

[0271] Figures 34A and 34B show cross-sectional views of a dynamic contact lens having a central dynamic portion (3401), a cavity (3402) (in a compressed state) behind the dynamic lens, and a protrusion (3403) on the front surface of the dynamic lens, and respective overlapping cavities (3402). The profile of the dynamic lens is shown in a non-conforming configuration (Figure 34A) and a conforming configuration (Figure 34B). In the non-conforming configuration, the cavity is in a compressed state, and in the conforming configuration, the cavity is in a non-compressed state. The protrusion (3403) facilitates the ability of the cavity to be compressed using the pressure applied by the eyelid.

[0272] Figures 35A and 35B show cross-sectional views of a dynamic contact lens similar to that shown in Figures 34A and 34B, but the positions of the protrusion and the cavity do not coincide. The dynamic lenses shown in Figures 35A and 35B have a dynamic portion (3501), a cavity (3502) behind the dynamic lens, and a protrusion (3503) on the front surface of the peripheral portion of the dynamic lens, and non-overlapping cavities (3502). The profile of the dynamic lens is shown in a non-conforming configuration (Figure 35A) and a conforming configuration (Figure 35B). In the non-conforming configuration, the cavity is in a compressed state, and in the conforming configuration, the cavity is in a non-compressed state. The protrusion (3503) facilitates the ability of the cavity to be compressed using the pressure applied by the eyelid.

[0273] Figures 36A and 36B show cross-sectional views of a dynamic contact lens having a central dynamic portion (3601) and a cavity (3602) behind the dynamic lens. The dynamic portion (3601) has a non-uniform thickness, such that the center (3605) is thicker than the outer peripheral transition zone (3606) having the peripheral portion (3607). The profile of the dynamic lens is shown in a non-conforming configuration (Figure 36A) and a conforming configuration (Figure 36B). In the non-conforming configuration, the cavity (3602) is in a compressed state, and in the conforming configuration, the cavity (3602) is in a non-compressed state.

[0274] Figures 37A and 37B show cross-sectional views of a dynamic contact lens having a central dynamic portion (3701) and a cavity (3702) behind the dynamic lens. The dynamic portion (3701) has a non-uniform thickness, and as a result, the center (3705) is thinner than the outer peripheral transition zone (3706) having a peripheral portion (3707). The profile of the dynamic lens is shown in a non-conforming configuration (Figure 37A) and a conforming configuration (Figure 37B). In the non-conforming configuration, the cavity (3702) is in a compressed state, and in the conforming configuration, the cavity (3702) is in a non-compressed state.

[0275] Figures 38A and 38B show cross-sectional views of a dynamic contact lens having a central dynamic portion (3801) and a protrusion (3803) on the front surface of the dynamic lens. The dynamic portion (3801) has a non-uniform thickness, and as a result, the center (3805) is thinner than the outer peripheral transition zone (3806) having a peripheral portion (3807). The profile of the dynamic lens is shown in a non-conforming configuration (Figure 38A) and a conforming configuration (Figure 38B).

[0276] Figures 39A and 39B show cross-sectional views of a dynamic contact lens having a central dynamic portion (3901), a cavity (3902) behind the dynamic lens, and a protrusion (3903) covering each cavity (3902). The dynamic portion (3901) has a non-uniform thickness, and as a result, the center (3805) is thinner than the outer peripheral transition zone (3906) having a peripheral portion (3907). The profile of the dynamic lens is shown in a non-conforming configuration (Figure 39A) and a conforming configuration (Figure 39B). In the non-conforming configuration, the cavity (3902) is in a non-compressed state, and in the conforming configuration, the cavity (3902) is in a compressed state. In the conforming configuration, the protrusion (3903) is compressible to provide a substantially smooth front surface.

[0277] Figures 40A and 40B show cross-sectional views of a dynamic contact lens having a central dynamic portion (4001), a cavity (4002) behind the dynamic lens, and a protrusion (4003) overlapping each cavity (4002). The dynamic portion (4001) has a non-uniform thickness, and as a result, the central portion (4005) is thinner than the outer peripheral transition zone (4006) having a peripheral portion (4007). The profile of the dynamic lens is shown in a non-conforming configuration (Figure 40A) and a conforming configuration (Figure 40B). In the non-conforming configuration, the cavity (4002) is in a non-compressed state, and in the conforming configuration, the cavity (4002) is in a compressed state. The protrusions (4003) are not compressible or are partially compressible such that they protrude from the front surface.

[0278] Figures 41A and 41B show cross-sectional views of a dynamic contact lens having a central dynamic portion (4101), a cavity (4102) behind the dynamic lens, and a protrusion (4103) not coinciding with the position of the cavity (4102). The dynamic portion (4101) has a non-uniform thickness, and as a result, the central portion (4105) is thinner than the outer peripheral transition zone (4106) having a peripheral portion (4007). The profile of the dynamic lens is shown in a non-conforming configuration (Figure 41A) and a conforming configuration (Figure 41B). In the non-conforming configuration, the cavity (4102) is in a non-compressed state, and in the conforming configuration, the cavity (4102) is in a non-compressed state. The protrusions (4103) are not compressible or are partially compressible such that they protrude from the front surface.

[0279] Figures 33A - 41B show dynamic contact lenses in non-conforming and conforming configurations. The dynamic contact lens can exhibit at least one second non-conforming configuration with a gap height different from other non-conforming configurations. The conforming configuration and one or more non-conforming configurations are metastable.

[0280] The rear surface of the dynamic portion, the rear surface of the peripheral portion, or both the rear surfaces of the dynamic portion and the peripheral portion can include a surface treatment.

[0281] The surface treatment can be configured to control, modify, and / or select the adhesive and cohesive forces of the tears to the rear surface of the dynamic portion, the rear surface of the peripheral portion, or both the rear surfaces of the dynamic portion and the peripheral portion.

[0282] The surface treatment may be applied to all or part of the inner rear surface and / or the peripheral rear surface of the dynamic contact lens.

[0283] In a dynamic contact lens including a cavity, the surface treatment may be applied to the wall of the cavity and / or to channels extending from the cavity.

[0284] The surface treatment can include, for example, a coating, a thin film, a chemical treatment, a plasma treatment, or any combination thereof.

[0285] The surface treatment can be selected to modify the hydrophobicity or hydrophilicity of the rear surface of the dynamic part, the rear surface of the peripheral part, or both the rear surface of the dynamic part and the peripheral part.

[0286] The surface treatment can be selected to control and / or adjust the capillary force between the rear surface of the dynamic part and the cornea.

[0287] The surface treatment can be selected to control and / or promote the flow of tears in and out of the tear lens.

[0288] The rear surface of the dynamic contact lens can include a substance selected to control the hydrophilicity / hydrophobicity of the rear surface. The rear surface can include a substance selected to control the charge of the rear surface, the polarity of the rear surface, or a combination thereof.

[0289] Dk is the oxygen gas permeability, i.e., the amount of oxygen passing through a device such as a dynamic contact lens under any time and pressure difference conditions. Dk is also known as a barrier, 10 -11 (cm / sec)(mL O 2)(in units of mL×mmHg). The oxygen permeability can be expressed as Dk / t, where t is the thickness of the structure such as a dynamic contact lens, and thus Dk / t represents the amount of oxygen passing through a dynamic contact lens of a specific thickness under pressure difference conditions over a given fixed time. The oxygen permeability is in units of barrers / cm or 10 -9 (cm / sec)(mL O 2 )(mL×mmHg).

[0290] Eye health is promoted by lens materials having oxygen gas permeability. In dynamic contact lenses, it is generally desirable for the oxygen gas permeability to be greater than about 80 Dk. This high oxygen gas permeability will be difficult to achieve with high modulus materials and / or thicker material cross-sections.

[0291] The dynamic and peripheral portions of the dynamic contact lens can include materials characterized by an oxygen gas permeability of from about 10 Dk to about 500 Dk, from about 50 Dk to about 400 Dk, from about 50 Dk to about 300 DK, and in certain embodiments from about 50 DK to about 100 DK.

[0292] The dynamic contact lens may include silicon or silicone hydrogel having ionoporosity. For example, the dynamic contact lens may include silicone hydrogel or silicon having a low ion permeability, and the range of water can be from about 5% to about 35%, and as a result, Dk is 100×10 -11 or greater. The low ion permeability can include an iontophoretic ion permeability coefficient of about 0.25×10 -3 cm 2 / sec or less, for example about 0.08×10 -3 cm 2 / sec or less.

[0293] The dynamic contact lens may include a wettable surface coating disposed on at least the front surface of the dynamic contact lens, such that the tear film is smooth on the dynamic contact lens. The wettable surface coating may include a smooth coating for the comfort of the patient, for example, to smooth the eye when the patient blinks. The wettable coating may produce a contact angle of about 80° or less. For example, the coating may produce a contact angle of about 70° or less, and the contact angle may be in the range of about 55° to 65° to provide a surface with a smooth tear layer for vision. For example, the wettable coating can be disposed on both the upper and lower surfaces of the device, i.e., the front and back surfaces of the dynamic contact lens. The upper surface may include a wettable coating extending over at least the inner optical portion.

[0294] The wettable coating may include one or more suitable materials. For example, the wettable coating may include polyethylene glycol (PEG), and the PEG coating can be disposed on Parylene™. Alternatively, the wettable coating may include a plasma coating, and the plasma coating may include a luminous chemical vapor deposition (LCVD) film. For example, the plasma coating may include a hydrocarbon such as CH 4 , O 2 , or a fluorinated hydrocarbon such as CF 4 coating. Alternatively, or in combination, the wettable coating may include a polyethylene glycol (PEG) coating, or 2-hydroxyethyl methacrylate (HEMA). For example, the wettable coating may include HEMA disposed on a Parylene™ coating, or the wettable coating may include N-vinylpyrrolidone (NVP) disposed on a Parylene™ coating.

[0295] The dynamic contact lens provided by the present disclosure can have 10 wt% to 70 wt% of moisture, such as 30 wt% to 60 wt%, where wt% is based on the total weight of the dynamic contact lens.

[0296] The dynamic contact lens provided by the present disclosure can be manufactured using any method suitable for manufacturing contact lenses, particularly soft contact lenses. An example of a suitable method is compression molding. Once manufactured, the dynamic contact lens can be made such that the dynamic portion bulges outwards to form a dome, a bulge near the center, or other forward surface profiles.

[0297] The method of manufacturing a dynamic contact lens includes, for example, the step of forming a dynamic contact lens, the dynamic contact lens comprising: a dynamic portion having a SAG height and a central thickness, where the central thickness is less than the SAG height; and a peripheral portion connected to the dynamic portion, the peripheral portion being configured to hold the dynamic contact lens on the cornea. The method of manufacturing a dynamic contact lens includes, for example, the step of forming a dynamic contact lens, the dynamic contact lens comprising: a dynamic portion characterized by a dynamic base curve; and a peripheral portion connected to the dynamic portion, the peripheral portion including a peripheral base curve, the dynamic base curve being different from the peripheral base curve. For example, the radius of curvature of the dynamic portion can be less than the radius of curvature of the peripheral portion. For example, the radius of curvature of the dynamic portion can be less than the radius of curvature of the peripheral portion near the center, the peripheral portion near the center being part of the transition zone and the peripheral portion adjacent to the dynamic portion. The material used to manufacture the dynamic lens can be a material suitable for use in conventional soft contact lenses. The material can include, for example, a Young's modulus of 0.05 MPa to 30 MPa, 0.1 MPa to 20 MPa, 0.1 MPa to 10 MPa, 0.1 MPa to 5 MPa, or 0.1 MPa to 2 MPa.

[0298] The dynamic contact lens provided by the present disclosure can be manufactured with a manufactured SAG height. The manufactured central SAG height refers to the distance from the rear surface at the center of the dynamic part to the extension of the base curve for the peripheral part near the center adjacent to the dynamic part. The manufactured central SAG height is shown as element (110) in FIG. 1A, where the dashed line is the extension of the base curve of the peripheral part near the center under the dynamic part. The manufactured central SAG height is the maximum gap achievable when the lens is placed on the cornea and when the dynamic part is filled with tears to form a tear lens. Depending on many factors including the availability of tears, a dynamic part with a manufactured central SAG height of 40 μm can produce a quasi-stable tear lens having a gap of, for example, 40 μm, 30 μm, 20 μm, and / or 10 μm. A dynamic part with a manufactured central SAG height of 100 μm can produce a quasi-stable tear lens having a gap of, for example, 100 μm, 90 μm, 80 μm, 70 μm, 60 μm, 50 μm, 40 μm, 30 μm, and / or 10 μm.

[0299] The dynamic contact lens provided by the present disclosure can be used to correct or improve vision.

[0300] A method of correcting a patient's vision can include the step of applying a dynamic contact lens provided by the present disclosure to the eye of a patient in need of corrected vision.

[0301] Vision correction can include correction of farsightedness, nearsightedness, astigmatism, or presbyopia.

[0302] The method provided by the present disclosure includes the step of treating presbyopia in a patient's eye by applying a dynamic contact lens provided by the present disclosure.

[0303] The dynamic contact lens provided by the present disclosure can be designed to dynamically correct vision. For example, presbyopia is characterized by the inability to focus the eyes on nearby objects. The dynamic part of the dynamic contact lens provided by the present disclosure can be dynamically reconfigured to accommodate either farsighted or nearsighted vision. For example, with respect to presbyopia, in a first configuration suitable for viewing distant objects, the dynamic part of the dynamic contact lens can be proximal to the cornea. In this configuration, there is no tear lens, and farsighted vision is uncorrected. Next, when the patient views a nearby object, the dynamic part of the dynamic contact lens can assume a second configuration that corrects presbyopia and facilitates clear viewing of nearby objects. This is done without changing the radius thickness of the dynamic part or the curvature ratio of the dynamic part. Rather, as the dynamic part bulges outward, the lens-shaped volume expands to provide a tear lens that helps dynamically correct nearsighted vision. The tear lens changes the light intensity of the dynamic part of the dynamic contact lens.

[0304] The dynamic contact lens provided by the present disclosure can also be used as a multifocal lens to correct presbyopia and prevent the progression of myopia.

[0305] The static configuration of the dynamic contact lens provided by the present disclosure can be used to treat astigmatism, or to supplement an irregular cornea for corneal wound healing.

[0306] A dynamic contact lens incorporating a tear lens can correct the vision resulting from an irregularly shaped cornea. The irregularly shaped cornea can be permanent or temporary, such as resulting from eye surgery including laser refractive keratectomy or corneal cross-linking. The tear lens can correct astigmatism. In the treatment of such conditions, the dynamic contact lens provided by the present disclosure with a static tear lens may be appropriate.

[0307] The dynamic contact lens provided by the present disclosure can be used for enhancing or restoring vision following eye treatment. Eye treatment can include manipulation of eye tissue and can relate to lesions outside the optical region. Eye treatment can include incising the eye tissue and implanting a device within the optical region. In certain embodiments, eye treatment includes excising at least a portion of the stroma and / or epithelium. Eye treatment includes, for example, cataract surgery including phacoemulsification, conventional extracapsular cataract extraction, and intracapsular cataract extraction; glaucoma surgery including laser trabeculoplasty, iridotomy, iridectomy, sclerotomy, goniosynechialysis, drainage implant surgery, and tube shunt surgery; corneal surgery including corneal transplantation, penetrating keratoplasty, artificial corneal transplantation, pterygium excision, corneal tattooing, and osteo-ondonto-keratoprosthesis (OOKP); and photorefractive treatment including photorefractive keratectomy (PRK) and laser in-situ keratomileusis (LASIK). Eye treatment can further include treatment of eye trauma, where the treatment may or may not include eye surgery. Eye treatment can include cataract surgery, corneal inlay surgery, corneal transplantation, or treatment of an eye trauma wound. Eye treatment can include incising and / or perforating the cornea at a site outside the optical region.

[0308] Generally, eye treatments such as cataract surgery, corneal inlay surgery, and corneal transplantation can be distinguished from eye treatments that involve operations only on the optical region of the cornea or mainly on the optical region of the cornea. In the former type of eye treatment, which can be regarded as a transplantation in which a device is implanted into eye tissue as an accessory or replacement for the removed eye tissue, the surgery involves operations on eye tissue outside the optical region in addition to the optical region itself. The latter type of treatment is exemplified by refractive correction surgery in which the optical region of the cornea is cut to correct refractive vision defects. Examples of refractive correction surgery include, for example, PRK and LASIK. Eye treatments that involve operations on the optical region of the cornea are included to the extent that the treatment further involves operations on eye tissue outside the optical region. For example, LASIK involves making an incision in the stroma outside the optical region to form a flap. The flap is then lifted back to expose the stroma and then excised using a laser to provide a shape for refractive correction. Furthermore, photorefractive surgery that involves operations on tissue outside the optical region and operations on tissue within the optical region of the eye can be combined. For example, corneal inlay surgery such as the ReLEx procedure and related photorefractive surgery can be combined.

[0309] The dynamic contact lens provided by the present disclosure may be used to treat the cornea following corneal inlay surgery or corneal anlay surgery. Corneal inlays and anlays are small lenses or other optical devices that are inserted into the cornea to reform the front surface of the eye, i.e., the front surface of the cornea, in order to improve vision and may in some cases resemble small contact lenses. The main current use of corneal inlays is to improve near vision and address presbyopia. In some cases, corneal inlay surgery can be combined with photorefractive surgery such as LASIK to correct both presbyopia and common refractive disorders such as myopia, hyperopia, and / or astigmatism.

[0310] The dynamic contact lens provided by the present disclosure may be used to treat the cornea following cataract surgery. In certain embodiments, the treatment of the eye includes cataract surgery. Cataract surgery involves the removal and replacement of the natural lens of the eye, which is called a cataract, that has become cloudy.

[0311] The dynamic contact lens provided by the present disclosure may be used to treat the cornea following corneal transplantation. Corneal transplantation treatments include, for example, penetrating keratoplasty, lamellar keratoplasty, deep anterior lamellar keratoplasty, and endothelial keratoplasty.

[0312] The dynamic contact lens provided by the present disclosure accelerates the healing of eye defects when applied to a patient's eye following treatment of the eye. Eye defects include incisions and perforations of the cornea and / or other eye tissues.

[0313] The dynamic contact lens provided by the present disclosure may be used to treat the cornea following crosslinking treatment. Corneal crosslinking is a technique that strengthens chemical bonds in the cornea, thereby promoting the cornea's ability to resist irregular changes in its shape, known as ectasia.

[0314] The dynamic contact lenses provided by the present disclosure may be used, for example, for treating the cornea following photorefractive therapy such as PRK and LASIK. Refractive eye surgery is used to improve the refractive state of the eye and includes, for example, automated lamellar keratoplasty (ALK), LASIK (laser assisted in-situ keratomileusis), photorefractive keratectomy (PRK), LASEK (laser assisted sub-epithelium keratomileusis), EPI-LASIK, radial keratotomy, mini asymmetric radial keratotomy, arcuate keratotomy, LRI (limbal relaxing incision), thermokeratoplasty, laser thermokeratoplasty, intrastromal corneal ring segment removal, and phakic intraocular lens implantation, among other surgeries. Following any of these surgeries, there is a period of time until optimal vision is restored. For example, in LASIK, optimal vision is typically achieved within about 24 hours following surgery. During this recovery period, in addition to sub-optimal vision, patients may experience discomfort such as photophobia or light sensitivity and / or a burning sensation. A method is desired to reduce the time to achieve optimal vision and to reduce or eliminate the discomfort associated with refractive eye surgery.

[0315] PRK is a surgical procedure in which a laser is used to form a stroma to correct refractive defects. In the process, the epithelium that overlaps the excised stromal portion is removed to form an epithelial defect.

[0316] LASIK is a surgical procedure used to correct refractive vision defects such as myopia, hyperopia, and astigmatism, where a laser is used to reshape the cornea to improve vision, such as the clarity and sharpness of an image. The LASIK procedure involves both a surgical cut of the cornea and laser ablation. During LASIK, the eye is fixed by the application of a soft corneal suction ring. Next, a flap is created on the outer cornea using a blade or laser, leaving a hinge at one end of the flap. The flap is then folded back to expose the stroma, or middle portion of the cornea. A laser is then used to vaporize the corneal stroma, removing tissue to reshape the cornea and correct vision. After the stromal layer is reformed, the flap is repositioned over the eye and stays in place by natural adhesion. Optimal vision is usually achieved within about 24 hours following the surgery.

[0317] The dynamic contact lens provided by the present disclosure can be configured to correct refractive disorders such as astigmatism. The lens provides a smooth spherical front surface and minimizes the distortion introduced by the lens by reducing the flexibility of the inner optical portion and maintaining the centration of the lens during wear. The reduction in the flexibility of the inner optical portion can be done, in part, by increasing the rigidity of the inner portion and by creating a tear lens. The centration of the inner optical portion minimizes astigmatism and prism effects caused by the tilt of the optical element and further minimizes edge distortion.

[0318] The foregoing has focused on the treatment of the eye related to intentional manipulation of the eye, but it can also be recognized that the dynamic contact lens and methods of using the dynamic contact lens may also be useful for the treatment of other injuries to the eye, such as the treatment of traumatic wounds. Trauma to the eye can also cause edema and damage the interfaces between various eye tissues. Thus, in addition to postoperative methods, the dynamic contact lens provided by the present disclosure is useful for the healing of traumatic wounds to the eye. Trauma includes, for example, physical trauma such as blunt and sharp trauma, chemical injury, blast injury, burns, and psychological trauma. Treatment of traumatic wounds may include surgery such as removing an embedded object or removing scar tissue. To the extent that the trauma produces edema and visual abnormalities, application of the dynamic contact lens results in faster visual recovery and accelerates healing by stabilizing the involved eye tissues. Trauma can also result in defects in eye tissues including the front surface of the cornea and can involve the epithelium and / or stroma and damage to the internal eye tissues. Thus, wound healing includes the healing of wounds related to physical damage to eye tissues that is not necessarily brought about by surgery.

[0319] The dynamic contact lens provided by the present disclosure may also be used as a protective device. For example, the dynamic contact lens may be used to protect the eye from potential injuries such as trauma by providing protection from physical trauma, chemicals, particulates, and edema. As a protective device, the dynamic contact lens can be applied to the eye prior to anticipated exposure to potential trauma. When worn to protect the eye from potential trauma, the dynamic contact lens can provide a physical barrier, a chemical barrier by sealing the front surface of the eye, and / or prevent or minimize edema caused by intangible forces such as blowing pressure or trauma imparted to other parts of the body. In certain embodiments, protecting the eye from potential trauma includes protecting the eye from gases, vapors, dust, or smoke. In certain embodiments, protection includes protection from edema.

Examples

[0320] Embodiments provided by the present disclosure are further illustrated by reference to the following examples, which describe the dynamic contact lenses provided by the present disclosure and the use of dynamic contact lenses.

[0321] Example 1: Optical function of a dynamic contact lens in an eye model

[0322] A diagram of a dynamic contact lens having a dynamic portion is shown in FIG. 11. The letter "A" was applied to the model cornea, and the dynamic contact lens was applied over the letter and the model cornea. Features on the left and right sides of the simulated eyelid. In FIG. 11, no pressure was applied to the cornea.

[0323] As shown in FIG. 12, when pressure is applied to the dynamic contact lens by moving the simulated eyelid towards the center, i.e., towards the dynamic portion, the refraction of the dynamic central portion shifted to a more posterior light intensity. As a result, the size of the letter "A" was approximately 170% larger.

[0324] As shown in FIG. 13, when the artificial eyelid pressure was released from the lens by moving the simulated eyelid away from the central dynamic portion, the refractive power of the dynamic central portion returned to the initial light intensity within approximately 100 milliseconds.

[0325] Saline solution was used to simulate tears.

[0326] Example 2: Optical function of a dynamic contact lens having a tear reservoir in an eye model

[0327] A dynamic contact lens having a dynamic portion and a peripheral tear reservoir was placed on an eye model and imaged by OCT.

[0328] As shown in Fig. 14A, the dynamic part (1401) at the right end of the image is in a conforming state. There is no tear lens between the lens and the model cornea (1402). The tear reservoir (1403) with a height of 144 μm is evident on the left side of the image.

[0329] As shown in Fig. 14B, when light pressure was applied onto the tear reservoir, the height of the reservoir (1403) decreased to 120 μm, and the dynamic part (1401) assumed a non-conforming configuration to form a tear lens (1404) with a gap height of 76 μm.

[0330] Example 3: Optical Function of the Lens in an Eye Model

[0331] A dynamic contact lens with a dynamic part was placed on the eye of a 50-year-old male human.

[0332] The dynamic contact lens had the following characteristics: a base curve of 8.9 mm, a diameter of 14.5 mm, a central thickness of 100 μm, a thickness of 10 mm, a radius of 200 μm, a SAG of 200 μm, and a diameter of the dynamic part of 20 mm.

[0333] The correction of the eye refraction was measured using a standard autorefractor.

[0334] The correction of the eye refraction was determined to be -2.25 D, and the base curve of the cornea was 7.4 mm.

[0335] A dynamic contact lens with a dynamic part was placed on the eye. The dynamic part (1501) conformed to the cornea (1502), and as shown by the OCT image in Fig. 15, there was no obvious gap between the back surface of the dynamic part and the cornea. The refractive correction required for the eye was +3.5 D, and the front curvature of the lens was 7.52 mm. This indicated that the light intensity of the lens was -5.75 D (-2.25 D for correction (required for the uncorrected eye) +3.5 D (additional myopic shift by the lens)).

[0336] Next, pressure was applied to the peripheral portion of the dynamic contact lens. The dynamic portion (1501) exhibited a non-conforming configuration as shown by the OCT image of FIG. 16. A gap (1503) was clearly visible between the rear surface of the dynamic portion and the cornea (1502). The refractive correction required for the eye in the non-conforming configuration was -2.75D, indicating that the strength of the tear lens (1503) added an optical strength of +6.25D (+3.5D plus the 2.75D of the hyperopic shift) to the optical system.

[0337] Example 4: Tear lens formation on a human eye

[0338] The dynamic contact lens provided by the present disclosure was applied to a human eye.

[0339] FIG. 17A shows a tear reservoir (1701) having a height of 76 μm at primary fixation. The regions of the human eye imaged by OCT are identified in FIG. 17B for each section.

[0340] Example 5: Dynamic portion near the center

[0341] A dynamic contact lens having a dynamic portion was applied onto the human cornea. The dynamic portion (1003) was installed in the region near the center of the dynamic contact lens. As shown in FIG. 10, the non-conforming dynamic portion is eccentric with respect to the lens center. In the conforming configuration, the dynamic portion adds a positive optical strength to the eye.

[0342] Example 6: Configuration and dimensions of an example of a dynamic contact lens

[0343] The configuration and dimensions of an example of a dynamic contact lens are shown in FIGS. 18 - 20.

[0344] FIG. 18 shows a dynamic contact lens having a path / ridge opening towards a central bulge and a peripheral 360° groove. The dynamic lens is designed such that when pressure is applied by the lower eyelid onto a sector of the groove, the tear fluid can be oriented centrally.

[0345] Figure 19 shows a dynamic contact lens having six (6) tear pockets in the periphery with a path / bump opening towards the central bulge. The dynamic lens is designed such that tears can be oriented centrally when pressure is applied by the lower eyelid onto the sectors of the groove.

[0346] Figure 20 shows a dynamic contact lens having a peripheral 360° groove with dimensions similar to those of the dynamic part.

[0347] Example 7: The negative lens has a dynamic part.

[0348] Figure 21 shows an OCT image of the central dynamic part (2101) forming a negative tear lens (2102). The thickness of the central dynamic part decreases towards the center of the dynamic part. Figure 22 shows a negative tear lens (2202) where the center of the lens conforms to the cornea (2203). The thickness at the center of the dynamic part is thinner than the thickness in the transition zone having a periphery.

[0349] Example 8: Effect of lens parameters on internal forces, see Example 11 below.

[0350] The effect of the manufactured shape of the dynamic part on the shape of the dynamic part when applied to the patient's eye is shown in Figures 25A - 25C.

[0351] Figure 25A shows the relationship of the gap between the back surface of the dynamic part and the cornea with respect to the manufactured SAG height of the dynamic part.

[0352] For example, referring to FIG. 25A, in a dynamic contact lens made of a silicon hydrogel having a Young's modulus of 0.76 MPa and having a manufactured central SAG height of about 10 μm over a diameter of 3 mm (equal to a radius of curvature of 4.72 mm), when applied to an eye having an anterior curvature of 7.6 mm, the gap between the posterior surface at the center of the dynamic portion and the cornea is about 100 μm. The gap height is an equilibrium between the restoring force generated by the manufactured SAG height and the availability of the tear fluid. The gap height depends on the availability of the tear fluid. For example, as shown in FIG. 25A, the gap height is only about 10% of the manufactured SAG height. Using additional tear fluid, the gap height can be maximally 100% of the manufactured SAG height. The availability of the tear fluid can be controlled and / or facilitated by including fluid reservoirs, channels, surface apertures, and other physical features that promote the exchange of tear fluid with the tear lens within the gap defined by the dynamic portion. The dynamic lens has a diameter of 14.5 mm, a dynamic portion with a diameter of 3 mm, a central thickness of 200 μm, and is made of silicon hydrogel.

[0353] FIG. 25B shows an OCT image of a dynamic contact lens having a silicon hydrogel with a Young's modulus of 0.76 MPa, having a manufactured SAG height of 40 μm over a diameter of 3 mm (equal to a radius of curvature of 6.19 mm) on the eye with an anterior curvature of 7.6 mm, and having a tear lens with a gap height of 37 μm.

[0354] FIG. 25C shows an OCT image of a dynamic contact lens having a silicon hydrogel with a Young's modulus of 0.76 MPa, having a manufactured SAG height of 100 μm over a diameter of 3 mm (equal to a radius of curvature of 4.72 mm) on the eye with an anterior curvature of 7.6 mm, and having a tear lens with a gap height of 96 μm.

[0355] To generate the tear lens shown in FIGS. 25B and 25C, tear fluid is provided under the peripheral portion and made to flow under the dynamic portion to form the tear lens. Both images demonstrate that the dynamic lens can achieve its complete pre-manufactured possible SAG to generate a tear lens under the entire pre-manufactured SAG. Thus, assuming the use of a soft contact lens material and having a manufactured central dynamic portion where the dynamic lens has a smaller radius of curvature than the peripheral or near-peripheral portion, a gap higher than 10 μm is formed between the dynamic portion and the cornea. See also the graph of FIG. 25A. Further, if more tear fluid is available to form a tear lens between the dynamic portion and the cornea, the dynamic portion can further jump away from the cornea.

[0356] The availability of tear fluid can depend on several factors, including the lens geometry, features that facilitate the flow or exchange of tear fluid such as reservoirs, channels and surface apertures, the manufactured SAG height, and the pressure applied to the lens by the eyelid. A dynamic contact lens with a manufactured SAG height of 60 μm to 110 μm (the distance between the back surface of the dynamic portion at the center of the lens and the peripheral base curve) was manufactured, applied to the eye, and the gap between the back surface of the dynamic portion and the cornea was measured. The relationship between the manufactured SAG height and the gap height reflects the internal mechanical forces caused by the pre-manufactured dome on the geometry of the metastable non-conforming configuration. The larger the pre-manufactured SAG height, the greater the pumping force generated.

[0357] The internal mechanical forces can also be increased by increasing the thickness of the dynamic portion, by reducing the diameter of the dynamic portion, and by increasing the Young's modulus of the material forming the dynamic portion. These effects are illustrated in FIGS. 26A - 26C, which show graphs of the gap between the back surface at the center of the dynamic portion and the cornea, where the manufactured SAG height for the dynamic portion has thicknesses of 200 μm (FIG. 26A), 250 μm (FIG. 26B), and 300 μm (FIG. 26C). As can be appreciated, FIGS. 26A - 26C represent a dynamic portion with an increase in rigidity.

[0358] As the manufactured thickness of the dynamic part increased, the internal force increased and the gap height increased. The silicone hydrogel lens had a modulus of 0.76 MPa, a lens diameter of 14.5 mm, a dynamic part diameter of 3 mm, and a base curve of 8.9. For each thickness of the dynamic part, the manufactured SAG height varied from 50 μm to 250 μm.

[0359] Example 9: Dynamic lens with a peripheral bulge

[0360] A schematic cross-sectional view of a dynamic contact lens having a bulge on the front surface of the peripheral portion is shown in FIG. 27. The dynamic lens has a diameter of 14.5 mm, a central thickness of 200 μm, a pre-manufactured SAG of 200 μm, the diameter of the dynamic part is 3 mm, and the peripheral bulge has a total thickness including a bulge of 350 μm and a thickness of the peripheral portion of 550 μm. The dynamic lens shown in FIG. 27 includes a dynamic part (2401) having a thickness of 200 μm and a manufactured SAG height (2402) of 100 μm, a cavity (2403) in the peripheral portion (2405), and protrusions (2404) with various thicknesses up to 350 μm overlapping the cavity (2403).

[0361] A photograph of the lens placed on the eye is shown in FIG. 28. FIG. 28 shows a photograph of a dynamic contact lens with an applied bulge on the eye (upper left), and a schematic cross-sectional view of the dynamic contact lens on the cornea (lower right), including the dynamic part (2802), the peripheral part (2803), the bulge (2804), and the eyelid (2805).

[0362] A dynamic lens with a peripheral bulge was placed on a human eye and imaged by OCT during primary (forward) fixation (FIG. 29) and downward fixation (FIG. 30). During primary fixation, the dynamic part conformed to the cornea, and during downward fixation, the dynamic part bulged outwards to form a tear lens with a gap height of 16 μm. In another example, as shown in FIG. 31, for a dynamic lens with a manufactured bulge, the gap of the tear lens was 38 μm.

[0363] Example 10: Dynamic lens with a flat periphery

[0364] The dynamic lens was manufactured with the following parameters: Material type: SH65 silicone hydrogel; Material modulus: 200 MPa; Central thickness (CT): 200 μm; R0 - OZ optical part: 1.5 μm; SAG (bulge gap): 110 μm; Rl (near the edge band) 4.5 μm; BC1 (near the peripheral BC): 89 μm; R2 (total lens diameter): 14.5 μm; BC2 (distal peripheral BC): 11 μm; Transition radius: (round corner between OZ and near the periphery, 0 = acute angle) 1 μm; and End shape: chisel. In this dynamic lens, the radius of curvature of the peripheral part is larger (flatter profile) than that of other dynamic lenses.

[0365] Figure 32 shows that by flattening the peripheral profile to an 11 mm base curve, the gap between the back surface of the dynamic part and the cornea increased.

[0366] Example 11: Design of a dynamic contact lens

[0367] Generally, the structure of the dynamic lens is based on a nominal lens geometric design common in the field of soft contact lenses, such that at least the peripheral part conforms to the cornea, enabling both comfort and fluid flow under the lens.

[0368] The nominal dynamic contact lens can have an average back optical zone radius (BOZR) similar to the corneal anterior curvature (7 mm - 9 mm), which can be uniform (e.g., the same BOZR for all lens diameters, such as 8.9 mm), or different BOZRs for different lens diameters to promote the performance of a lens that conforms to the asperities of the cornea / sclera.

[0369] The nominal dynamic lens can have, for example, two peripheral curvatures, a central BOZR of 7.86 mm (+1.5 mm) for a central diameter of 10 mm (+1.5 mm), and a flatter BOZR at the periphery of 9.3 mm (+1.5 mm). The transition between the two BOZR curvatures can be smoothed by a continuous and gradual change or a fillet can be used. The dynamic lens can have a standard diameter (~14 mm) made of a standard soft contact lens material such as silicone hydrogel and can have standard optical transparency. The dynamic contact lens can have a standard edge such as a rounded edge or a deeply engraved (chisel) edge.

[0370] The diameter of the dynamic part of the dynamic lens can be, for example, from 1 mm to 7 mm such as 2 mm to 4 mm. The dynamic lens can be manufactured to feature different curvatures in the profile. For example, the central dynamic part can be manufactured with a steeper base curve such as a bulge, such that the SAG height between the center of the dynamic part and the surrounding curved surface is from 10 μm to 200 μm. The transition zone between the two curvatures, i.e., between the curvature of the dynamic part and the periphery, may be smoothed by one or more transition curves or fillets to eliminate or minimize local pressure points and to facilitate fluid exchange with the underlying tear lens of the dynamic part. Parameters that promote the performance of the dynamic part to deform include, for example, thickness, material modulus, general lens geometry, the area and diameter of the dynamic part, and the base curve of the dynamic part.

[0371] The transition zone between the dynamic part and the periphery may be scored on the back surface of the lens by a groove having a width, for example, from 50 μm to 1,000 μm (to relieve pressure from the dynamic part and to allow for fluid availability). The groove can traverse the transition zone between the dynamic part and the surrounding periphery. The number of grooves can be in the range of, for example, 1 to 12, and the length of the groove can be in the range of, for example, from 0.5 mm to the lens edge of the dynamic lens (~7 mm).

[0372] One or more of the grooves can be connected to a cavity, one or more surface openings, or both the cavity and one or more surface openings.

[0373] Assuming a 7.6 mm centrally curved cornea, a tear lens having a power of 4 diopters requires a SAG of 14 μm across an optical zone of 3 mm diameter, or 26 μm for an optical zone of 4 mm diameter, or 41 μm for an optical zone of 5 mm diameter.

[0374] Table 1 shows the calculated light intensity resulting from different manufactured (produced) SAG heights of 40 μm or 100 μm, assuming that the gap of the tear lens is equal to the manufactured SAG height, for optical zones having diameters from 3 mm to 5.8 mm.

[0375] [Table 1]

[0376] Aspects of the Invention

[0377] Aspect 1A. A contact lens including a dynamic portion, where the dynamic portion includes a conforming configuration configured to provide a first light intensity to an eye having a cornea; and at least one non-conforming configuration configured to provide a second light intensity to the eye, the second light intensity being different from the first light intensity.

[0378] Aspect 2A. The contact lens of Aspect 1A, where the contact lens includes a central geometric axis; and the dynamic portion is disposed on the central geometric axis, near the center of the central geometric axis, deviating from the central geometric axis, or any combination thereof.

[0379] Aspect 3A. The contact lens of any one of Aspects 1A-2A, where the conforming configuration is configured to substantially conform to the cornea.

[0380] Aspect 4A. The contact lens of any one of Aspects 1A-3A, where the conforming configuration is configured to adhere to the cornea.

[0381] Aspect 5A. A contact lens according to any one of Aspects 1A-4A, wherein the conforming configuration is configured to adhere to the cornea by capillary force.

[0382] Aspect 6A. A contact lens according to any one of Aspects 1A-5A, wherein at least one non-conforming configuration includes a single non-conforming configuration, one or more separate non-conforming configurations, or a continuous range of non-conforming configurations.

[0383] Aspect 7A. A contact lens according to any one of Aspects 1A-6A, wherein at least one non-conforming configuration is configured to provide a tear lens between the rear surface of the dynamic part and the front surface of the cornea.

[0384] Aspect 8A. A contact lens according to any one of Aspects 1A-7A, wherein the contact lens is configured such that when applied to the cornea, the dynamic part presents a conforming configuration for a first vision and at least one non-conforming configuration for a second vision.

[0385] Aspect 9A. The contact lens of Aspect 8A, wherein each of the first vision and the second vision independently includes distance vision, intermediate vision, or near vision.

[0386] Aspect 10A. A contact lens according to any one of Aspects 1A-9A, further including at least one first mechanism configured to induce a change between the conforming configuration and at least one non-conforming configuration; and at least one second mechanism configured to induce a change between at least one non-conforming configuration and the conforming configuration.

[0387] Aspect 11A. A contact lens according to Aspect 10A, wherein at least one first mechanism, at least one second mechanism, or both at least one first mechanism and at least one second mechanism include the step of operating one or more tear reservoirs; the one or more tear reservoirs are disposed between the rear surface of the moving part and the front surface of the cornea; and the one or more tear reservoirs are fluidly connected to the tears between the rear surface of the moving part and the front surface of the cornea.

[0388] Aspect 12A. A contact lens according to Aspect 11A, wherein the one or more tear reservoirs are symmetrically disposed around the moving part.

[0389] Aspect 13A. A contact lens according to Aspect 11A, wherein the one or more tear reservoirs are asymmetrically disposed around the moving part.

[0390] Aspect 14A. A contact lens according to any one of Aspects 1A - 13A, wherein at least some of the one or more tear reservoirs are compressible.

[0391] Aspect 15A. A contact lens according to any one of Aspects 1A - 14A, wherein at least some of the one or more tear reservoirs are compressible by a force in the range of 0.1 gm of force to 10 gm of force.

[0392] Aspect 16A. A contact lens according to any one of Aspects 1A - 15A, wherein the one or more tear reservoirs are configured to compress when pressure is applied by the eyelid; and the one or more tear reservoirs are configured to expand when pressure is not applied by the eyelid.

[0393] Aspect 17A. A contact lens according to any one of Aspects 1A - 16A, wherein the one or more tear reservoirs are configured to compress when pressure is applied by the eyelid only during a change in gaze.

[0394] Aspect 18A. A contact lens according to any one of Aspects 1A-17A, wherein one or more tear reservoirs are adjacent to a dynamic part.

[0395] Aspect 19A. A contact lens according to Aspect 10A, wherein at least one first mechanism, at least one second mechanism, or both at least one first mechanism and at least one second mechanism include the step of exchanging tears by compressing the dynamic part or the periphery when pressure is applied to the contact lens by the eyelid during a gaze change.

[0396] Aspect 20A. A contact lens according to Aspect 10A, wherein at least one first mechanism, at least one second mechanism, or both at least one first mechanism and at least one second mechanism include a protrusion on the front surface of the contact lens configured to interact with the eyelid.

[0397] Aspect 21A. A contact lens according to any one of Aspects 1A-20A, further including an optical region, wherein the dynamic part overlaps at least a portion of the optical region.

[0398] Aspect 22A. A contact lens according to any one of Aspects 1A-21A, further including a periphery connected to the dynamic part, wherein the periphery is configured to hold the contact lens on the cornea.

[0399] Aspect 23A. A contact lens according to any one of Aspects 1A-22A, wherein the dynamic part includes a first material characterized by a first modulus; and the periphery includes a second material characterized by a second modulus.

[0400] Aspect 24A. A contact lens according to Aspect 23A, wherein the first material and the second material include the same material.

[0401] Aspect 25A. A contact lens according to Aspect 23A, wherein the first material and the second material do not include the same material.

[0402] Aspect 26A. A contact lens according to any one of Aspects 1A-25A, wherein the first modulus is greater than the second modulus.

[0403] Aspect 27A. A contact lens according to any one of Aspects 1A-25A, wherein the first modulus is less than the second modulus.

[0404] Aspect 28A. A contact lens according to any one of Aspects 1A-25A, wherein the first modulus is the same as the second modulus.

[0405] Aspect 29A. A contact lens according to any one of Aspects 1A-28A, wherein the first modulus is in the range of 0.05 MPa to 10 MPa; and the second modulus is in the range of 0.05 MPa to 10 MPa.

[0406] Aspect 30A. A contact lens according to any one of Aspects 1A-2A, wherein the first modulus is in the range of 0.1 MPa to 2 MPa; and the second modulus is in the range of 0.1 MPa to 2 MPa.

[0407] Aspect 31A. A contact lens according to any one of Aspects 1A-30A, wherein each of the first material and the second material independently comprises silicon, hydrogel, silicone hydrogel, or any combination thereof.

[0408] Aspect 32A. A contact lens according to any one of Aspects 1A-31A, wherein the dynamic part includes a central SAG height in the range of 5 μm to 300 μm with respect to the base curve behind the periphery in at least one non-conforming configuration.

[0409] Aspect 33A. A contact lens according to any one of Aspects 1A-32A, wherein the dynamic part includes a central thickness of 30 μm to 600 μm.

[0410] Aspect 34A. A contact lens according to any one of Aspects 1A - 33A, wherein the contact lens includes a rear surface; and at least a portion of the rear surface includes a substance, a surface treatment, or a combination thereof; and is selected to control the capillary force between at least a portion of the rear surface of the contact lens and the tear fluid, between the cornea and the tear fluid, between the rear surface of the contact lens and the cornea, or any combination thereof.

[0411] Aspect 35A. A contact lens according to any one of Aspects 1A - 34A, wherein the first light intensity does not provide a change in the light intensity to the eye; or the second light intensity does not provide a change in the light intensity to the eye.

[0412] Aspect 36A. A contact lens according to any one of Aspects 1A - 35A, wherein the conforming configuration provides a first change in the light intensity to the eye; and at least one non - conforming configuration provides a second change in the light intensity to the eye in addition to the first change in the light intensity.

[0413] Aspect 37A. A contact lens according to any one of Aspects 1A - 36A, wherein at least one of the conforming configuration and at least one non - conforming configuration is metastable.

[0414] Aspect 38A. A contact lens according to any one of Aspects 1A - 37A, wherein the dynamic portion includes the rear surface and includes a gap profile between the rear surface and the cornea, the gap profile includes a maximum gap difference, the maximum gap difference is the difference between the central gap height and the gap height at the outer periphery of the dynamic portion; the conforming configuration includes a first maximum gap difference; the non - conforming configuration includes a second maximum gap difference; and the second maximum gap difference is greater than the first maximum gap difference.

[0415] Aspect 39A. A contact lens according to any one of Aspects 1A - 38A, wherein the contact lens includes a manufactured shape; and the contact lens includes the manufactured shape in at least one of at least one non - conforming configuration.

[0416] Aspect 40A. A contact lens according to any one of Aspects 1A - 39A, wherein the contact lens includes a peripheral portion including a peripheral rear surface; the peripheral rear surface includes a peripheral base curve; the dynamic portion includes a dynamic rear surface; the dynamic rear surface includes a dynamic base curve; in a first conforming configuration, the dynamic base curve is substantially the same as the peripheral base curve, and in a second non - conforming configuration, the dynamic base curve deviates from the peripheral base curve.

[0417] Aspect 41A. A contact lens according to any one of Aspects 1A - 40A, wherein the cornea includes a corneal curvature; the dynamic portion includes a dynamic rear surface; the dynamic rear surface includes a dynamic base curve; and in a conforming configuration, the dynamic base curve is substantially the same as the corneal curvature.

[0418] Aspect 42A. A contact lens according to any one of Aspects 1A - 41A, wherein the contact lens includes a peripheral portion including a peripheral rear surface; the peripheral rear surface includes a peripheral base curve; the dynamic portion includes a central SAG height with respect to the peripheral base curve; and the dynamic portion is configured to exhibit a first configuration characterized by a first central SAG height with respect to the peripheral base curve and a second configuration characterized by a second central SAG height with respect to the peripheral base curve, and the first central SAG height and the second central SAG height are different.

[0419] Aspect 43A. A contact lens including: a peripheral portion including a peripheral rear surface and a peripheral front surface, wherein the peripheral rear surface includes a peripheral base curve; and a dynamic portion including a dynamic rear surface and a dynamic front surface, wherein at least the dynamic rear surface bulges away from the peripheral base curve toward the dynamic front surface.

[0420] Aspect 44A. A contact lens including: a dynamic portion including a dynamic rear surface having a dynamic base curve; and a peripheral portion connected to the dynamic portion and having a peripheral rear surface, wherein the peripheral rear surface includes a peripheral base curve; wherein in a first configuration, the dynamic base curve is substantially the same as the peripheral base curve, and in a second configuration, the dynamic base curve deviates from the peripheral base curve.

[0421] Aspect 45A. A contact lens having a dynamic portion including a dynamic back surface, the dynamic back surface having a dynamic base curve; wherein in a first configuration, the dynamic base curve is substantially the same as the corneal curvature; and in a second configuration, the dynamic base curve deviates from the corneal curvature.

[0422] Aspect 46A. A contact lens comprising: a peripheral portion including a peripheral back surface, the peripheral back surface including a peripheral base curve, the peripheral portion; and a dynamic portion connected to the peripheral portion, wherein the dynamic portion includes a central thickness and a central SAG height with respect to the peripheral base curve, the dynamic portion; wherein the dynamic portion exhibits a first configuration characterized by a first central SAG height with respect to the peripheral base curve, and a second configuration characterized by a second central SAG height with respect to the peripheral base curve, the first central SAG height and the second central SAG height being different; and the first configuration and the second configuration are in a metastable state.

[0423] Aspect 47A. A contact lens having a dynamic portion including a dynamic back surface, wherein the dynamic back surface includes a dynamic base curve; in a first configuration, the back surface includes a first base curve; and in a second configuration, the back surface includes a second base curve.

[0424] Aspect 48A. The contact lens of Aspect 47A, wherein the first configuration is configured to provide a first light intensity to an eye having a cornea; and the second configuration is configured to provide a second light intensity to the eye.

[0425] Aspect 49A. The contact lens of any one of Aspects 47A - 48A, wherein the first base curve is substantially the same as the corneal curvature.

[0426] Aspect 50A. A contact lens according to any one of Aspects 47A - 49A, comprising at least one first mechanism configured to cause a change between a first configuration and a second configuration; and at least one second mechanism configured to cause a change between the second configuration and the first configuration.

[0427] Aspect 51A. A contact lens comprising: a dynamic part, where the dynamic part includes at least one first non - conforming configuration configured to provide a first light intensity to an eye having a cornea; and at least one second non - conforming configuration configured to provide a second light intensity to the eye, where the second light intensity is different from the first light intensity; at least one first mechanism configured to cause a change between the first non - conforming configuration and the at least one second non - conforming configuration; and at least one second mechanism configured to cause a change between the at least one second non - conforming configuration and the at least one first non - conforming configuration.

[0428] Aspect 52A. A contact lens comprising: a first rear surface, a first front surface facing the first rear surface, and a first portion including a first material, where the first rear surface has a first radius of curvature; and the first material includes a first modulus, the first portion; and a second portion connected to the first portion, where the second portion includes a second rear surface, a second front surface facing the second rear surface, and a second material, where the second rear surface has a second radius of curvature; and the second material includes a second modulus; where the first radius of curvature is smaller than the second radius of curvature; and each of the first modulus and the second modulus is in the range of 0.05 MPa to 10 MPa, the second portion.

[0429] Aspect 53A. The contact lens of Aspect 52A, where the first portion is configured to provide a tear lens when applied to the eye; and the second portion is configured to hold the contact lens on the cornea.

[0430] Aspect 54A. A contact lens according to any one of Aspects 52A-53A, wherein each of the first modulus and the second modulus is in the range of 0.05 MPa to 3 MPa.

[0431] Aspect 55A. A contact lens according to any one of Aspects 52A-54A, wherein the first portion includes a central SAG height within the range of 5 μm to 300 μm with respect to the second radius of curvature on the back surface of the peripheral portion.

[0432] Aspect 56A. A contact lens including: a first back surface; a first front surface facing the first back surface; and a first portion including a first material, wherein the first material has a first modulus, the first portion; and a peripheral portion connected to the first portion, the peripheral portion includes a peripheral back surface having a base curve, and the second material has a second modulus; and the first back surface bulges forward from the base curve of the back surface of the peripheral portion; and each of the first modulus and the second modulus is in the range of 0.05 MPa to 10 MPa, the second portion.

[0433] Aspect 57A. A contact lens according to Aspect 56A, wherein each of the first modulus and the second modulus is in the range of 0.05 MPa to 3 MPa.

[0434] Aspect 58A. A contact lens according to any one of Aspects 56A-57A, wherein the first portion includes a central SAG height within the range of 5 μm to 300 μm with respect to the base curve of the back surface of the peripheral portion.

[0435] Aspect 59A. A method of correcting a patient's vision, including the step of applying a contact lens according to any one of Aspects 1A-51A to the eye of a patient in need of vision correction.

[0436] Aspect 60A. A method according to Aspect 59A, wherein the vision correction includes the step of correcting farsightedness, the step of correcting nearsightedness, the step of correcting astigmatism, or the step of correcting presbyopia.

[0437] Aspect 61A. The method of Aspect 59A, wherein the vision correction includes a step of slowing down the progression of myopia.

[0438] Aspect 62A. A method of treating presbyopia, including the step of applying to the patient's presbyopic eye any one of the contact lenses of Aspects 1A - 51A.

[0439] Aspect 63A. A method of correcting a patient's vision, including the step of applying to the eye of a patient in need of such treatment any one of the contact lenses of Aspects 52A - 58A.

[0440] Aspect 64A. The method of Aspect 63A, wherein the vision correction includes a step of treating an irregular cornea or astigmatism.

[0441] Aspect 65A. A method of treating a patient's eye following eye treatment, including the step of applying to the eye of a patient in need of such treatment any one of the contact lenses of Aspects 52A - 58A.

[0442] Aspect 66A. A method of healing a traumatic wound to the cornea of a patient's eye, including the step of applying to the eye of a patient in need of such healing any one of the contact lenses of Aspects 52A - 58A.

[0443] Aspect 67A. A method of protecting a patient's eye from possible injury, including the step of applying to the eye of a patient in need of such protection any one of the contact lenses of Aspects 52A - 58A.

[0444] Aspect 68A. A method of manufacturing a contact lens, including the step of shaping a material to provide the contact lens, the contact lens including: a peripheral portion including a peripheral rear surface and a peripheral front surface, the peripheral rear surface including a peripheral base curve; and a dynamic portion including a dynamic rear surface and a dynamic front surface, wherein at least the dynamic rear surface bulges away from the peripheral base curve toward the dynamic front surface.

[0445] Aspect 1. A dynamic contact lens comprising: a dynamic portion including a dynamic rear surface and a dynamic front surface facing the dynamic rear surface; a peripheral portion including a peripheral rear surface, a peripheral front surface facing the peripheral rear surface, and a transition zone connecting the peripheral portion and the dynamic portion; wherein the dynamic portion has a Young's modulus within the range of 0.05 MPa to 10 MPa and a manufactured central SAG height of 10 μm to 300 μm.

[0446] Aspect 2. The dynamic contact lens of Aspect 1, wherein the dynamic contact lens is configured to generate a tear lens to correct vision when applied to the cornea.

[0447] Aspect 3. The dynamic contact lens according to any one of Aspects 1-2, wherein when the dynamic contact lens is applied to the cornea, the dynamic portion can exhibit two or more metastable configurations, and the two or more metastable configurations are characterized by a gap difference between the central dynamic rear surface and the cornea.

[0448] Aspect 4. The dynamic contact lens according to any one of Aspects 1-3, wherein the dynamic portion has a diameter of 2.5 mm to 7 mm.

[0449] Aspect 5. The dynamic contact lens according to any one of Aspects 1-4, wherein the dynamic rear surface has a radius of curvature of 3 mm to 7.5 mm.

[0450] Aspect 6. The dynamic contact lens according to any one of Aspects 1-5, wherein the dynamic portion has a substantially uniform thickness.

[0451] Aspect 7. The dynamic contact lens according to any one of Aspects 1-6, wherein the dynamic portion has a substantially uniform thickness of 20 μm to 300 μm.

[0452] Aspect 8. The dynamic contact lens according to any one of Aspects 1-7, wherein the transition zone is configured to facilitate the flow of tears into the tear lens formed between the dynamic rear surface and the cornea when applied to the eye.

[0453] Aspect 9. A dynamic contact lens according to any one of Aspects 1-8, wherein the transition zone includes features configured to enhance the flexibility of the dynamic part.

[0454] Aspect 10. The dynamic contact lens of Aspect 9, wherein the features include smooth ends, a reduced cross-sectional thickness, grooves, or any combination thereof.

[0455] Aspect 11. A dynamic contact lens according to any one of Aspects 1-10, wherein the dynamic contact lens includes one or more channels on the peripheral rear surface extending from the dynamic part.

[0456] Aspect 12. The dynamic contact lens of Aspect 11, wherein each of the one or more channels extends radially from the dynamic part.

[0457] Aspect 13. A dynamic contact lens according to any one of Aspects 11-12, wherein the one or more channels include 3 to 20 channels.

[0458] Aspect 14. The dynamic contact lens of any one of Aspects 11-13, wherein each of the one or more channels has a width of 100 μm to 1,000 μm and a height of 50 μm to 200 μm.

[0459] Aspect 15. The dynamic contact lens of any one of Aspects 11-14, wherein each of the one or more channels has a length of 1 mm to 7 mm.

[0460] Aspect 16. The dynamic contact lens of any one of Aspects 11-15, wherein at least one of the channels is connected to one or more surface openings extending from the peripheral front surface.

[0461] Aspect 17. The dynamic contact lens of Aspect 16, wherein the one or more surface openings have a diameter of 200 μm to 600 μm.

[0462] Aspect 18. A dynamic contact lens according to any one of Aspects 1-17, further comprising one or more cavities on the peripheral rear surface.

[0463] Aspect 19. The dynamic contact lens of Aspect 18, wherein the peripheral rear surface includes 3 to 12 cavities.

[0464] Aspect 20. A dynamic contact lens according to any one of Aspects 18-19, wherein each of the one or more cavities independently has a depth under the rear outer peripheral surface of 10 μm to 500 μm.

[0465] Aspect 21. A dynamic contact lens according to any one of Aspects 1-20, further comprising one or more protrusions overlapping the peripheral front surface.

[0466] Aspect 22. The dynamic contact lens of Aspect 21, wherein the peripheral front surface includes 3 to 12 protrusions.

[0467] Aspect 23. A dynamic contact lens according to any one of Aspects 21-22, wherein each of the one or more protrusions independently has a height above the front outer peripheral surface of 10 μm to 200 μm.

[0468] Aspect 24. A dynamic contact lens comprising: a peripheral portion and a dynamic portion connected to the peripheral portion, wherein the dynamic portion includes a conforming configuration configured to provide a first light intensity to an eye having a cornea; and at least one non-conforming configuration configured to provide a second light intensity to the eye, the second light intensity being different from the first light intensity.

[0469] Aspect 25. The dynamic contact lens of Aspect 24, wherein when applied to the eye, in the conforming configuration, the dynamic portion substantially conforms to the front surface of the cornea; and in the non-conforming configuration, the dynamic portion does not conform to the front surface of the cornea.

[0470] Aspect 26. A dynamic contact lens according to any one of Aspects 24-25, wherein the conforming configuration and the non-conforming configuration are metastable.

[0471] Aspect 27. A dynamic contact lens according to any one of aspects 24-26, wherein the dynamic contact lens includes a central geometric axis; and the dynamic part is arranged on the central geometric axis, near the center of the central geometric axis, deviating from the central geometric axis, or any combination thereof.

[0472] Aspect 28. A dynamic contact lens according to any one of aspects 24-27, wherein when applied to the eye, in the conforming configuration, the dynamic part substantially conforms to the cornea.

[0473] Aspect 29. A dynamic contact lens according to any one of aspects 24-28, wherein when applied to the eye, in the conforming configuration, the dynamic part adheres to the cornea.

[0474] Aspect 30. A dynamic contact lens according to any one of aspects 24-29, wherein when applied to the eye, in the conforming configuration, the dynamic part adheres to the cornea by capillary force.

[0475] Aspect 31. A dynamic contact lens according to any one of aspects 24-30, wherein when applied to the eye, the dynamic part adheres to the cornea by mechanical force.

[0476] Aspect 32. A dynamic contact lens according to any one of aspects 24-31, wherein at least one non-conforming configuration includes a single non-conforming configuration, one or more separate non-conforming configurations, or a continuous range of non-conforming configurations.

[0477] Aspect 33. A dynamic contact lens according to any one of aspects 24-32, wherein at least one non-conforming configuration is configured to provide a tear lens between the rear surface of the dynamic part and the front surface of the cornea.

[0478] Aspect 34. A dynamic contact lens according to any one of aspects 24-33, wherein the dynamic contact lens is configured such that when applied to the cornea, the dynamic part presents a conforming configuration for a first vision and at least one non-conforming configuration for a second vision.

[0479] Aspect 35. The dynamic contact lens of aspect 34, wherein each of the first vision and the second vision independently includes distance vision, intermediate vision, or near vision.

[0480] Aspect 36. The dynamic contact lens of any one of aspects 24 - 35, further comprising at least one first feature configured to cause a change between a conforming configuration and at least one non-conforming configuration; wherein at least one includes the manufactured geometric shape of a dynamic part.

[0481] Aspect 37. The dynamic contact lens of aspect 36, wherein the geometric shape of the dynamic part includes a bulge that expands forward from the periphery.

[0482] Aspect 38. The dynamic contact lens of any one of aspects 24 - 37, further comprising: at least one first feature configured to cause a change between a conforming configuration and at least one non-conforming configuration; and at least one second feature configured to cause a change between at least one non-conforming configuration and a conforming configuration.

[0483] Aspect 39. The dynamic contact lens of aspect 38, wherein each of the first feature and the second feature is configured to cause a change in configuration by the pressure applied by the eyelid.

[0484] Aspect 40. The dynamic contact lens of aspect 39, wherein the pressure applied by the eyelid includes gazing downward, normal blinking, intentional blinking, keeping the eyelid closed for a period of time, or squeezing the eyelid against the eye for a period of time.

[0485] Aspect 41. The dynamic contact lens of any one of aspects 38 - 40, wherein at least one first feature and at least one second feature are the same feature.

[0486] Aspect 42. The dynamic contact lens of Aspect 24, further comprising at least one feature configured to cause a change in configuration by the pressure applied by the eyelid.

[0487] Aspect 43. The dynamic contact lens of Aspect 42, wherein the at least one feature includes one or more protrusions on the front surface of the dynamic contact lens.

[0488] Aspect 44. The dynamic contact lens of Aspect 43, wherein the one or more protrusions have a height with respect to the front surface within the range of 10 μm to 200 μm.

[0489] Aspect 45. The dynamic contact lens of any one of Aspects 43 - 44, wherein the one or more protrusions are disposed over a basic cavity on the rear surface of the dynamic contact lens.

[0490] Aspect 46. The dynamic contact lens of any one of Aspects 43 - 44, wherein the one or more protrusions include one or more ridges.

[0491] Aspect 47. The dynamic contact lens of any one of Aspects 42 - 46, wherein the at least one feature includes one or more features configured to increase friction.

[0492] Aspect 48. The dynamic contact lens of Aspect 47, wherein the one or more features are configured to increase friction and include grooves, indentations, surface apertures, ridges, or any combination thereof.

[0493] Aspect 49. The dynamic contact lens of any one of Aspects 38 - 49, wherein at least one first feature, at least one second feature, or both at least one first feature and at least one second feature include one or more tear reservoirs; the one or more tear reservoirs are disposed between the rear surface of the dynamic part and the front surface of the cornea; and the one or more tear reservoirs are fluidly connected to the tear between the rear surface of the dynamic part and the front surface of the cornea.

[0494] Aspect 50. The dynamic contact lens of Aspect 49, wherein one or more tear reservoirs are symmetrically arranged around the dynamic part.

[0495] Aspect 51. The dynamic contact lens of Aspect 49, wherein one or more tear reservoirs are asymmetrically arranged around the dynamic part.

[0496] Aspect 52. The dynamic contact lens of any one of Aspects 49 - 51, wherein at least some of the one or more tear reservoirs are compressible.

[0497] Aspect 53. The dynamic contact lens of any one of Aspects 49 - 52, wherein at least some of the one or more tear reservoirs are compressible by a force in the range of 0.1 gm of force to 10 gm of force.

[0498] Aspect 54. The dynamic contact lens of any one of Aspects 49 - 53, wherein one or more tear reservoirs are configured to compress when pressure is applied by the eyelid; and one or more tear reservoirs are configured to expand when pressure is not applied by the eyelid.

[0499] Aspect 55. The dynamic contact lens of any one of Aspects 49 - 54, wherein one or more tear reservoirs are configured to compress only during a change in gaze when pressure is applied by the eyelid.

[0500] Aspect 56. The dynamic contact lens of any one of Aspects 49 - 55, wherein one or more tear reservoirs are fluidly connected to the dynamic part.

[0501] Aspect 57. A dynamic contact lens according to any one of Aspects 36 - 56, wherein at least one first feature, at least one second feature, or both at least one first feature and at least one second feature include a step of exchanging tears by compression of a dynamic part or compression of a peripheral part when pressure is applied to the dynamic contact lens by an eyelid during a gaze change.

[0502] Aspect 58. A dynamic contact lens according to any one of Aspects 36 - 56, wherein at least one first feature, at least one second feature, or both at least one first feature and at least one second feature include a protrusion on a front surface of the dynamic contact lens configured to interact with an eyelid.

[0503] Aspect 59. A dynamic contact lens according to any one of Aspects 24 - 58, further including an optical region, wherein the dynamic part overlaps at least a part of the optical region.

[0504] Aspect 60. A dynamic contact lens according to any one of Aspects 24 - 59, wherein the peripheral part is configured to hold the dynamic contact lens on the cornea.

[0505] Aspect 61. A dynamic contact lens according to any one of Aspects 24 - 60, wherein the dynamic part includes a first material characterized by a first Young's modulus; and the peripheral part includes a second material characterized by a second Young's modulus.

[0506] Aspect 62. The dynamic contact lens of Aspect 61, wherein the first material and the second material include the same material.

[0507] Aspect 63. The dynamic contact lens of Aspect 61, wherein the first material and the second material include different materials.

[0508] Aspect 64. A dynamic contact lens according to any one of Aspects 61 and 63, wherein the first Young's modulus is greater than the second Young's modulus.

[0509] Aspect 65. A dynamic contact lens according to any one of Aspects 61 and 63, wherein the first Young's modulus is less than the second Young's modulus.

[0510] Aspect 66. A dynamic contact lens according to Aspect 61, wherein the first Young's modulus is the same as the second Young's modulus.

[0511] Aspect 67. A dynamic contact lens according to Aspect 61, wherein the first Young's modulus is in the range of 0.05 MPa to 10 MPa; and the second Young's modulus is in the range of 0.05 MPa to 10 MPa.

[0512] Aspect 68. A dynamic contact lens according to Aspect 61, wherein the first Young's modulus is in the range of 0.1 MPa to 2 MPa; and the second Young's modulus is in the range of 0.1 MPa to 2 MPa.

[0513] Aspect 69. A dynamic contact lens according to any one of Aspects 61 - 68, wherein each of the first material and the second material independently includes silicon, hydrogel, silicone hydrogel, or any combination thereof.

[0514] Aspect 70. A dynamic contact lens according to any one of Aspects 24 - 69, wherein the dynamic part includes a central gap height in the range of 5 μm to 300 μm with respect to the base curve behind the peripheral part in at least one non - conforming configuration.

[0515] Aspect 71. A dynamic contact lens according to any one of Aspects 24 - 70, wherein the dynamic part includes a central thickness of 30 μm to 600 μm.

[0516] Aspect 72. A dynamic contact lens according to any one of aspects 24-71, wherein the dynamic contact lens includes a rear surface; and at least a part of the rear surface includes a substance, a surface treatment, or a combination thereof; and is selected to control the capillary force between at least a part of the rear surface of the dynamic contact lens and the tear fluid, between the cornea and the tear fluid, between the rear surface of the dynamic contact lens and the cornea, or any combination thereof.

[0517] Aspect 73. A dynamic contact lens according to any one of aspects 24-72, wherein the first light intensity does not provide a change in light intensity to the eye; or the second light intensity does not provide a change in light intensity to the eye.

[0518] Aspect 74. A dynamic contact lens according to any one of aspects 24-73, wherein the conforming configuration provides a first change in light intensity to the eye; and at least one non-conforming configuration provides a second change in light intensity to the eye in addition to the first change in light intensity.

[0519] Aspect 75. A dynamic contact lens according to any one of aspects 24-75, wherein the conforming configuration and at least one of the non-conforming configurations are metastable.

[0520] Aspect 76. A dynamic contact lens according to any one of aspects 24-75, wherein the dynamic part includes a rear surface and includes a gap profile between the rear surface and the cornea, the gap profile includes a maximum gap difference, the maximum gap difference is the difference between the central gap height and the gap height at the outer periphery of the dynamic part; the conforming configuration includes a first maximum gap difference; the non-conforming configuration includes a second maximum gap difference; and the second maximum gap difference is greater than the first maximum gap difference.

[0521] Aspect 77. A dynamic contact lens according to any one of aspects 24-76, wherein the dynamic contact lens includes a manufactured shape; and the dynamic contact lens includes the manufactured shape in one of the non-conforming configurations.

[0522] Aspect 78. A dynamic contact lens according to any one of Aspects 24 - 77, wherein the dynamic contact lens includes a peripheral portion including a peripheral rear surface; the peripheral rear surface includes a peripheral base curve; the dynamic portion includes a dynamic rear surface; the dynamic rear surface includes a dynamic base curve; in a first conforming configuration, the dynamic base curve is substantially the same as the peripheral base curve, and in a second non-conforming configuration, the dynamic base curve deviates from the peripheral base curve.

[0523] Aspect 79. A dynamic contact lens according to any one of Aspects 24 - 78, wherein the cornea includes a corneal curvature; the dynamic portion includes a dynamic rear surface; the dynamic rear surface includes a dynamic base curve; and in a conforming configuration, the dynamic base curve is substantially the same as the corneal curvature.

[0524] Aspect 80. A dynamic contact lens according to any one of Aspects 24 - 79, wherein the dynamic contact lens includes a peripheral portion including a peripheral rear surface; the peripheral rear surface includes a peripheral base curve; the dynamic portion includes a central SAG height with respect to the peripheral base curve; and the dynamic portion is configured to exhibit a first configuration characterized by a first central clearance height with respect to the peripheral base curve and a second configuration characterized by a second central clearance height with respect to the peripheral base curve, and the first central SAG height and the second central clearance height are different.

[0525] Aspect 81. A dynamic contact lens including: a peripheral portion including a peripheral rear surface and a peripheral front surface, the peripheral rear surface including a peripheral base curve; and a dynamic portion including a dynamic rear surface and a dynamic front surface, wherein at least the dynamic rear surface bulges away from the peripheral base curve toward the dynamic front surface.

[0526] Aspect 82. A dynamic contact lens including: a dynamic portion including a dynamic rear surface having a dynamic base curve; and a peripheral portion connected to the dynamic portion and having a peripheral rear surface, the peripheral rear surface including a peripheral base curve; wherein in a first configuration, the dynamic base curve is substantially the same as the peripheral base curve, and in a second configuration, the dynamic base curve deviates from the peripheral base curve.

[0527] Aspect 83. A dynamic contact lens including a dynamic part, wherein the dynamic part includes a dynamic posterior surface; the dynamic posterior surface includes a dynamic base curve; in a first configuration, the dynamic base curve is substantially the same as the corneal curvature; and in a second configuration, the dynamic base curve deviates from the corneal curvature.

[0528] Aspect 84. A dynamic contact lens comprising: a peripheral part including a peripheral posterior surface that includes a peripheral base curve; and a dynamic part connected to the peripheral part, wherein the dynamic part includes a central thickness and a central SAG height with respect to the peripheral base curve; wherein the dynamic part exhibits a first configuration characterized by a first central clearance height with respect to the peripheral base curve and a second configuration characterized by a second central clearance height with respect to the peripheral base curve, the first central clearance height and the second central clearance height being different; and the first configuration and the second configuration are metastable states.

[0529] Aspect 85. A dynamic contact lens comprising a dynamic part including a posterior surface, wherein the posterior surface includes a dynamic base curve; in a first configuration, the posterior surface includes a first base curve; and in a second configuration, the posterior surface includes a second base curve.

[0530] Aspect 86. The dynamic contact lens of Aspect 85, wherein the first configuration is configured to provide a first light intensity to the eye; and the second configuration is configured to provide a second light intensity to the eye.

[0531] Aspect 87. The dynamic contact lens of any one of Aspects 85 - 86, wherein the first base curve is substantially the same as the corneal curvature.

[0532] Aspect 88. A dynamic contact lens according to any one of Aspects 85-87, comprising: at least one first mechanism configured to cause a change between a first configuration and a second configuration; and at least one second mechanism configured to cause a change between the second configuration and the first configuration.

[0533] Aspect 89. A dynamic contact lens comprising: at least one first non-conforming configuration configured to provide a first light intensity to an eye having a cornea; and at least one second non-conforming configuration configured to provide a second light intensity to the eye, wherein the second light intensity is different from the first light intensity, a dynamic part; at least one first mechanism configured to cause a change between the first non-conforming configuration and the at least one second non-conforming configuration; and at least one second mechanism configured to cause a change between the at least one second non-conforming configuration and the at least one first non-conforming configuration.

[0534] Aspect 90. A dynamic contact lens comprising: a first rear surface, a first front surface facing the first rear surface, and a first portion including a first material, wherein the first rear surface has a first radius of curvature; and the first material has a first Young's modulus, the first portion; and a second portion connected to the first portion, the second portion including a second rear surface, a second front surface facing the second rear surface, and a second material, wherein the second rear surface has a second radius of curvature; and the second material has a second Young's modulus, the second portion, wherein the first radius of curvature is smaller than the second radius of curvature; and each of the first Young's modulus and the second Young's modulus is independently in the range of 0.05 MPa to 10 MPa.

[0535] Aspect 91. The dynamic contact lens of Aspect 90, wherein the first portion is configured to provide a tear lens when applied to the eye; and the second portion is configured to hold the dynamic contact lens on the cornea.

[0536] Aspect 92. Any one of the dynamic contact lenses of aspects 90-91, wherein each of the first Young's modulus and the second Young's modulus is independently in the range of 0.05 MPa to 3 MPa.

[0537] Aspect 93. Any one of the dynamic contact lenses of aspects 90-92, wherein the first portion includes a central SAG height within the range of 5 μm to 300 μm with respect to the second radius of curvature of the rear surface of the peripheral portion.

[0538] Aspect 94. A dynamic contact lens comprising: a first rear surface; a first front surface facing the first rear surface; and a first portion including a first material, wherein the first material has a first Young's modulus, the first portion; and a peripheral portion connected to the first portion, the peripheral portion includes a peripheral rear surface having a base curve, and a second material has a second Young's modulus, and the first rear surface bulges forward from the base curve of the rear surface of the peripheral portion; and each of the first Young's modulus and the second Young's modulus is independently in the range of 0.05 MPa to 10 MPa.

[0539] Aspect 95. The dynamic contact lens of aspect 94, wherein each of the first Young's modulus and the second Young's modulus is independently in the range of 0.05 MPa to 3 MPa.

[0540] Aspect 96. Any one of the dynamic contact lenses of aspects 94-95, wherein the first portion includes a central SAG height within the range of 5 μm to 300 μm with respect to the base curve of the rear surface of the peripheral portion.

[0541] Aspect 97. A method of correcting a patient's vision, comprising the step of applying to the eye of a patient in need of corrected vision any one of the dynamic contact lenses of aspects 1-96.

[0542] Aspect 98. The method of aspect 97, wherein the vision correction includes the step of correcting farsightedness, the step of correcting nearsightedness, the step of correcting astigmatism, or the step of correcting presbyopia.

[0543] Aspect 99. A method according to any one of Aspects 97 to 98, wherein the vision correction includes a step of retarding the progression of myopia.

[0544] Aspect 100. A method of treating presbyopia, comprising the step of applying to the presbyopic eye of a patient any one of the dynamic contact lenses of Aspects 1 to 96.

[0545] Aspect 101. A method of correcting the vision of a patient, comprising the step of applying to the eye of a patient in need of such treatment any one of the dynamic contact lenses of Aspects 1 to 96.

[0546] Aspect 102. The method of Aspect 101, wherein the vision correction includes a step of treating an irregular cornea or astigmatism.

[0547] Aspect 103. A method of treating a patient's eye following eye treatment, comprising the step of applying to the eye of a patient in need of such treatment any one of the dynamic contact lenses of Aspects 1 - 96.

[0548] Aspect 104. A method of healing a traumatic wound to the cornea of a patient's eye, comprising the step of applying to the eye of a patient in need of such healing any one of the dynamic contact lenses of Aspects 1 - 96.

[0549] Aspect 105. A method of protecting a patient's eye from a potential injury, comprising the step of applying to the eye of a patient in need of such protection any one of the dynamic contact lenses of Aspects 1 - 96.

[0550] Aspect 106. A method of manufacturing a dynamic contact lens, comprising the step of shaping a material to provide a dynamic contact lens, the contact lens comprising: a peripheral portion including a peripheral rear surface and a peripheral front surface, the peripheral rear surface including a peripheral base curve; and a dynamic portion including a dynamic rear surface and a dynamic front surface, wherein at least the dynamic rear surface bulges away from the peripheral base curve toward the dynamic front surface.

[0551] Aspect 107. The method of Aspect 106, wherein the peripheral part comprises a first material characterized by a first Young's modulus; and the moving part comprises a second material characterized by a second Young's modulus; wherein each of the first Young's modulus and the second Young's modulus is from 0.05 MPa to 30 MPa.

[0552] Aspect 108. The method according to any one of Aspects 106 - 107, wherein each of the first Young's modulus and the second Young's modulus is from 0.1 MPa to 2 MPa.

[0553] Aspect 109. A method of manufacturing a dynamic contact lens, comprising the step of shaping a material to provide a dynamic contact lens, the dynamic contact lens comprising: a moving part characterized by a dynamic base curve; and a peripheral part connected to the moving part, wherein the peripheral part comprises a peripheral base curve, and the dynamic base curve is different from the peripheral base curve.

[0554] Aspect 110. The method of Aspect 109, wherein the radius of curvature of the curvature of the moving part is less than the radius of curvature of the peripheral part.

[0555] Aspect 111. The method according to any one of Aspects 109 - 110, wherein the radius of curvature of the moving part is less than the radius of curvature of the peripheral part of the para - center, and the peripheral part of the para - center is adjacent to the moving part.

[0556] Aspect 112. A dynamic contact lens according to any one of Aspects 1 - 96, adapted to be applied to the cornea.

[0557] Alternative methods exist for implementing the embodiments disclosed herein. Accordingly, the present embodiments are illustrative and not to be considered limiting. Furthermore, the claims are not limited to the details provided herein and have the full scope and the rights of their equivalents.

Claims

1. 1. A dynamic contact lens comprising: a dynamic portion including a dynamic rear surface and a dynamic front surface opposite the dynamic rear surface; a periphery including a posterior peripheral surface, a anterior peripheral surface opposite the posterior peripheral surface, and a transition zone joining the periphery and the dynamic portion; where the dynamic part is: A material having a Young's modulus in the range of 0.05 MPa to 10 MPa; and Manufactured median SAG heights between 10 μm and 300 μm A dynamic contact lens comprising:

2. The dynamic contact lens of claim 1 , wherein the dynamic contact lens is configured to generate a tear lens to correct vision when applied to the cornea.

3. The dynamic contact lens of claim 1, wherein when the dynamic contact lens is applied to the cornea, the dynamic portion can assume two or more metastable configurations, the two or more metastable configurations being characterized by a gap difference between the central dynamic posterior surface and the cornea.

4. The dynamic contact lens of claim 1 , wherein the dynamic portion has a diameter of between 2.5 mm and 7 mm.

5. The dynamic contact lens of claim 1 , wherein the dynamic posterior surface has a radius of curvature between 3 mm and 7.5 mm.

6. The dynamic contact lens of claim 1 , wherein the dynamic portion has a substantially uniform thickness.

7. The dynamic contact lens of claim 1, wherein the dynamic portion has a substantially uniform thickness of between 20 μm and 300 μm.

8. The dynamic contact lens of claim 1 , wherein the transition zone is configured to promote tear flow to a tear lens formed between the dynamic posterior surface and the cornea when applied to an eye.

9. The dynamic contact lens of claim 1 , wherein the transition zone includes features configured to increase the flexibility of the dynamic portion.

10. The dynamic contact lens of claim 9 , wherein the features include smooth edges, reduced cross-sectional thickness, grooves, or any combination thereof.

11. The dynamic contact lens of claim 1 , wherein the dynamic contact lens includes one or more channels in the peripheral posterior surface extending from the dynamic portion.

12. The dynamic contact lens of claim 11 , wherein each of the one or more channels extends radially from the dynamic portion.

13. The dynamic contact lens of claim 11, wherein the one or more channels comprises between 3 and 20 channels.

14. The dynamic contact lens of claim 11, wherein each of the one or more channels has a width between 100 μm and 1,000 μm and a height between 50 μm and 200 μm.

15. The dynamic contact lens of claim 11, wherein each of the one or more channels has a length between 1 mm and 7 mm.

16. The dynamic contact lens of claim 11 , wherein at least one of the channels is connected to one or more surface openings extending from the peripheral anterior surface.

17. The dynamic contact lens of claim 16, wherein the one or more surface openings have a diameter of between 200 μm and 600 μm.

18. The dynamic contact lens of claim 1 further comprising one or more cavities on the peripheral posterior surface.

19. The dynamic contact lens of claim 18, wherein the peripheral posterior surface comprises between 3 and 12 cavities.

20. 20. The dynamic contact lens of claim 18, wherein each of the one or more cavities independently has a depth below the posterior periphery of between 10 μm and 500 μm.

21. The dynamic contact lens of claim 1 further comprising one or more protrusions overlying the peripheral anterior surface.

22. 22. The dynamic contact lens of claim 21, wherein the peripheral anterior surface comprises between 3 and 12 protrusions.

23. 22. The dynamic contact lens of claim 21, wherein each of the one or more protrusions independently has a height above the anterior periphery of between 10 μm and 200 μm.

24. 1. A dynamic contact lens comprising: Periphery; A dynamic portion coupled to the periphery, the dynamic portion comprising: a matching arrangement configured to provide a first light intensity to an eye having a cornea; and at least one non-conforming arrangement configured to provide a second light intensity to the eye, the second light intensity being different from the first light intensity; A dynamic contact lens comprising:

25. 25. The dynamic contact lens of claim 24, wherein when applied to the eye, in the conforming configuration, the dynamic portion substantially conforms to the anterior surface of the cornea; and in the non-conforming configuration, the dynamic portion does not conform to the anterior surface of the cornea.

26. The dynamic contact lens of claim 24 , wherein the conforming and non-conforming configurations are metastable.

27. The dynamic contact lens includes a central geometric axis; and The dynamic portion is positioned on the central geometric axis, paracentric to the central geometric axis, offset from the central geometric axis, or any combination thereof.

25. The dynamic contact lens of claim 24.

28. 25. The dynamic contact lens of claim 24, wherein when applied to the eye, in the conforming configuration, the dynamic portion substantially conforms to the cornea.

29. 25. The dynamic contact lens of claim 24, wherein when applied to the eye, in the conforming configuration, the dynamic portion adheres to the cornea.

30. 25. The dynamic contact lens of claim 24, wherein when applied to the eye, in the fitted configuration, the dynamic portion adheres to the cornea by capillary forces.

31. 25. The dynamic contact lens of claim 24, wherein when applied to the eye, the dynamic portion adheres to the cornea by mechanical force.

32. The dynamic contact lens of claim 24 , wherein the at least one non-compatible configuration comprises a single non-compatible configuration, one or more separate non-compatible configurations, or a continuous range of non-compatible configurations.

33. 25. The dynamic contact lens of claim 24, wherein the at least one non-conforming configuration is configured to provide a tear lens between a posterior surface of the dynamic portion and an anterior surface of the cornea.

34. The dynamic contact lens of claim 24, wherein the dynamic portion is configured to assume a matching configuration for a first vision and at least one non-matching configuration for a second vision when applied to the cornea.

35. 35. The dynamic contact lens of claim 34, wherein each of the first vision and the second vision independently comprises distance vision, intermediate vision, or near vision.

36. 25. The dynamic contact lens of claim 24, further comprising at least one first feature configured to cause a change between a conforming configuration and at least one non-conforming configuration; wherein at least one includes a manufactured geometric shape of the dynamic portion.

37. 37. The dynamic contact lens of claim 36, wherein the geometric shape of the dynamic portion includes a bulge extending forward from the periphery.

38. at least one first feature configured to cause a change between a conforming configuration and at least one non-conforming configuration; and At least one second feature configured to cause a change between at least one non-compliant configuration and a compliant configuration. The dynamic contact lens of claim 24 further comprising:

39. 40. The dynamic contact lens of claim 38, wherein each of the first feature and the second feature is configured to cause a change in configuration due to pressure exerted by an eyelid.

40. 40. The dynamic contact lens of claim 39, wherein the pressure exerted by the eyelid includes downward gazing, normal blinking, intentional blinking, holding the eyelid closed for a period of time, or squeezing the eyelid against the eye for a period of time.

41. 40. The dynamic contact lens of claim 38, wherein the at least one first characteristic and the at least one second characteristic are the same characteristic.

42. 25. The dynamic contact lens of claim 24, further comprising at least one feature configured to cause a change in configuration by pressure exerted by an eyelid.

43. 43. The dynamic contact lens of claim 42, wherein the at least one feature comprises one or more protrusions on the anterior surface of the dynamic contact lens.

44. The dynamic contact lens of claim 43, wherein the one or more protrusions have a height relative to the anterior surface in the range of 10 μm to 200 μm.

45. 44. The dynamic contact lens of claim 43, wherein the one or more protrusions are disposed over a basal cavity on the posterior surface of the dynamic contact lens.

46. 44. The dynamic contact lens of claim 43, wherein the one or more protrusions include one or more ridges.

47. 43. The dynamic contact lens of claim 42, wherein the at least one feature includes one or more features configured to increase friction.

48. 48. The dynamic contact lens of claim 47, wherein the one or more features are configured to increase friction and include grooves, indentations, surface openings, ridges, or any combination thereof.

49. at least one first feature, at least one second feature mechanism, or both at least one first feature and at least one second feature include one or more tear reservoirs; The one or more tear reservoirs are disposed between the posterior surface of the dynamic portion and the anterior surface of the cornea; and the one or more tear reservoirs are fluidly connected to the tear fluid between the posterior surface of the dynamic portion and the anterior surface of the cornea; 39. The dynamic contact lens of claim 38.

50. 50. The dynamic contact lens of claim 49, wherein the one or more tear reservoirs are symmetrically disposed about the dynamic portion.

51. 50. The dynamic contact lens of claim 49, wherein the one or more tear reservoirs are asymmetrically positioned about the dynamic portion.

52. 50. The dynamic contact lens of claim 49, wherein at least some of the one or more tear reservoirs are compressible.

53. 50. The dynamic contact lens of claim 49, wherein at least some of the one or more tear reservoirs are compressible by a force in the range of 0.1 gm force to 10 gm force.

54. The one or more tear reservoirs are configured to compress when pressure is applied by the eyelid; and the one or more tear reservoirs are configured to expand when pressure is not applied by the eyelid; 50. The dynamic contact lens of claim 49.

55. 50. The dynamic contact lens of claim 49, wherein the one or more tear reservoirs are configured to compress when pressure is applied by the eyelid only during gaze changes.

56. 50. The dynamic contact lens of claim 49, wherein the one or more tear reservoirs are fluidly connected to the dynamic portion.

57. 37. The dynamic contact lens of claim 36, wherein the at least one first feature, the at least one second feature, or both the at least one first feature and the at least one second feature include replacing tears by dynamic portion compression or peripheral compression when pressure is applied to the dynamic contact lens by the eyelid during gaze changes.

58. 37. The dynamic contact lens of claim 36, wherein the at least one first feature, the at least one second feature, or both the at least one first feature and the at least one second feature comprise a protrusion on an anterior surface of the dynamic contact lens configured to interact with an eyelid.

59. 25. The dynamic contact lens of claim 24, wherein the dynamic contact lens further comprises an optical zone, the dynamic portion overlapping at least a portion of the optical zone.

60. 25. The dynamic contact lens of claim 24, wherein the peripheral portion is configured to hold the dynamic contact lens on the cornea.

61. 25. The dynamic contact lens of claim 24, wherein the dynamic portion comprises a first material characterized by a first Young's modulus; and the peripheral portion comprises a second material characterized by a second Young's modulus.

62. 62. The dynamic contact lens of claim 61, wherein the first material and the second material comprise the same material.

63. 62. The dynamic contact lens of claim 61, wherein the first material and the second material comprise different materials.

64. 62. The dynamic contact lens of claim 61, wherein the first Young's modulus is greater than the second Young's modulus.

65. 62. The dynamic contact lens of claim 61, wherein the first Young's modulus is less than the second Young's modulus.

66. 62. The dynamic contact lens of claim 61, wherein the first Young's modulus is the same as the second Young's modulus.

67. 62. The dynamic contact lens of claim 61, wherein the first Young's modulus is in the range of 0.05 MPa to 10 MPa; and the second Young's modulus is in the range of 0.05 MPa to 10 MPa.

68. 62. The dynamic contact lens of claim 61, wherein the first Young's modulus is in the range of 0.1 MPa to 2 MPa; and the second Young's modulus is in the range of 0.1 MPa to 2 MPa.

69. 62. The dynamic contact lens of claim 61, wherein each of the first material and the second material independently comprises a silicone, a hydrogel, a silicone hydrogel, or any combination thereof.

70. 25. The dynamic contact lens of claim 24, wherein the dynamic portion, in at least one non-conforming configuration, comprises a central gap height relative to the base curve of the peripheral posterior surface within the range of 5 μm to 300 μm.

71. The dynamic contact lens of claim 24, wherein the dynamic portion comprises a central thickness of from 30 μm to 600 μm.

72. 25. The dynamic contact lens of claim 24, wherein the dynamic contact lens comprises a posterior surface; and at least a portion of the posterior surface comprises a substance, a surface treatment, or a combination thereof; selected to control capillary forces between at least a portion of the posterior surface of the dynamic contact lens and tears, between the cornea and tears, between the posterior surface of the dynamic contact lens and the cornea, or any combination thereof.

73. 25. The dynamic contact lens of claim 24, wherein the first light intensity does not provide a change in light intensity to the eye; or the second light intensity does not provide a change in light intensity to the eye.

74. The dynamic contact lens of claim 24, wherein the adaptive configuration provides a first change in light intensity to the eye; and the at least one non-adaptive configuration provides a second change in light intensity to the eye in addition to the first change in light intensity.

75. 25. The dynamic contact lens of claim 24, wherein at least one of the conforming configuration and the non-conforming configuration is metastable.

76. the dynamic portion includes a posterior surface and includes a gap profile between the posterior surface and the cornea, the gap profile including a maximum gap difference, the maximum gap difference being the difference between a central gap height and a gap height at a periphery of the dynamic portion; The matching configuration includes a first maximum gap difference; the non-compliant configuration includes a second maximum gap difference; and the second maximum gap difference is greater than the first maximum gap difference.

25. The dynamic contact lens of claim 24.

77. The dynamic contact lens comprises a manufactured shape; and The dynamic contact lens includes a manufactured shape in one of the non-conforming configurations.

25. The dynamic contact lens of claim 24.

78. The dynamic contact lens includes a peripheral portion that includes a peripheral posterior surface; The peripheral posterior surface includes a peripheral base curve; The dynamic portion includes a dynamic posterior surface; The dynamic posterior surface includes a dynamic base curve; In a first fitting configuration, the dynamic base curve is substantially the same as the peripheral base curve; and In a second non-conforming configuration, the dynamic base curve deviates from the peripheral base curve.

25. The dynamic contact lens of claim 24.

79. The cornea includes the corneal curvature; The dynamic portion includes a dynamic posterior surface; The dynamic posterior surface includes a dynamic base curve; and In the fitted configuration, the dynamic base curve is substantially the same as the corneal curvature.

25. The dynamic contact lens of claim 24.

80. The dynamic contact lens includes a peripheral portion that includes a peripheral posterior surface; The peripheral posterior surface includes a peripheral base curve; The dynamic portion includes the median SAG height relative to the peripheral base curve; and the dynamic portion is configured to exhibit a first configuration characterized by a first central gap height relative to the peripheral base curve and a second configuration characterized by a second central gap height relative to the peripheral base curve, the first central gap height and the second central gap height being different; 25. The dynamic contact lens of claim 24.

81. 1. A dynamic contact lens comprising: a peripheral portion including a peripheral posterior surface and a peripheral anterior surface, the peripheral posterior surface including a peripheral base curve; and a dynamic portion including a dynamic posterior surface and a dynamic anterior surface, where at least the dynamic posterior surface bulges away from the peripheral base curve toward the dynamic anterior surface; A dynamic contact lens comprising:

82. 1. A dynamic contact lens comprising: a dynamic portion including a dynamic posterior surface having a dynamic base curve; a peripheral portion coupled to the dynamic portion and having a peripheral posterior surface, the peripheral posterior surface including a peripheral base curve; and In a first configuration, the dynamic base curve is substantially the same as the peripheral base curve; In a second configuration, the dynamic base curve deviates from the peripheral base curve. Dynamic contact lenses.

83. A dynamic contact lens comprising a dynamic portion, The dynamic portion includes a dynamic posterior surface; The dynamic posterior surface includes a dynamic base curve; In a first configuration, the dynamic base curve is substantially the same as the corneal curvature; and In a second configuration, the dynamic base curve deviates from the corneal curvature. Dynamic contact lenses.

84. 1. A dynamic contact lens comprising: a periphery, where the periphery includes a peripheral posterior surface, the peripheral posterior surface including a peripheral base curve; and a dynamic portion coupled to the peripheral portion, the dynamic portion including a central thickness and a central SAG height relative to the peripheral base curve; where the dynamic portion is configured to exhibit a first configuration characterized by a first central gap height relative to the peripheral base curve and a second configuration characterized by a second central gap height relative to the peripheral base curve; the first central gap height and the second central gap height are different; and the first configuration and the second configuration are metastable states; Dynamic contact lenses.

85. 1. A dynamic contact lens comprising a dynamic portion including a posterior surface, The posterior surface includes a dynamic base curve; In the first configuration, the posterior surface includes a first base curve; and In a second configuration, the posterior surface includes a second base curve. Dynamic contact lenses.

86. The first arrangement is configured to provide a first light intensity to the eye; and The second arrangement is configured to provide a second light intensity to the eye.

86. The dynamic contact lens of claim 85.

87. 86. The dynamic contact lens of claim 85, wherein the first base curve is substantially the same as the corneal curvature.

88. at least one first mechanism configured to cause a change between a first configuration and a second configuration; and At least one second mechanism configured to cause a change between the second configuration and the first configuration.

86. The dynamic contact lens of claim 85, further comprising:

89. 1. A dynamic contact lens comprising: A dynamic portion, wherein the dynamic portion comprises: at least one first non-conforming arrangement configured to provide a first light intensity to an eye having a cornea; and at least one second non-conforming configuration configured to provide a second light intensity to the eye, the second light intensity being different from the first light intensity; A dynamic portion including: at least one first mechanism configured to cause a change between a first non-compliant configuration and at least one second non-compliant configuration; at least one second mechanism configured to cause a change between the at least one second non-compliant configuration and the at least one first non-compliant configuration; A dynamic contact lens comprising:

90. 1. A dynamic contact lens comprising: a first portion including a first rear surface, a first front surface opposite the first rear surface, and a first material, the first posterior surface has a first radius of curvature; and a first portion, the first material having a first Young's modulus; and a second portion coupled to the first portion, the second portion including a second rear surface and a second front surface opposite the second rear surface, and a second material, the second posterior surface has a second radius of curvature; and a second portion, the second material having a second Young's modulus; where the first radius of curvature is less than the second radius of curvature; and each of the first Young's modulus and the second Young's modulus independently is in the range of 0.05 MPa to 10 MPa; Dynamic contact lenses.

91. the first portion is configured to provide a tear lens when applied to the eye; and The second portion is configured to hold a dynamic contact lens on the cornea.

91. The dynamic contact lens of claim 90.

92. 91. The dynamic contact lens of claim 90, wherein each of the first Young's modulus and the second Young's modulus is independently in the range of 0.05 MPa to 3 MPa.

93. 91. The dynamic contact lens of claim 90, wherein the first portion comprises a central SAG height relative to the second radius of curvature of the peripheral posterior surface within the range of 5 μm to 300 μm.

94. 1. A dynamic contact lens comprising: a first portion including a first posterior surface, a first anterior surface opposite the first posterior surface, and a first material, where the first material has a first Young's modulus; and a periphery coupled to the first portion, the periphery comprising: a peripheral posterior surface having a base curve; and a periphery, the second material having a second Young's modulus; where the first posterior surface bulges forward from a base curve of the peripheral posterior surface; and each of the first Young's modulus and the second Young's modulus independently is in the range of 0.05 MPa to 10 MPa; Dynamic contact lenses.

95. 95. The dynamic contact lens of claim 94, wherein each of the first Young's modulus and the second Young's modulus is independently in the range of 0.05 MPa to 3 MPa.

96. 95. The dynamic contact lens of claim 94, wherein the first portion comprises a central SAG height, relative to the peripheral posterior surface base curve, within the range of 5 μm to 300 μm.

97. A method of correcting the vision of a patient comprising applying to an eye of a patient in need thereof a dynamic contact lens according to any one of claims 1 to 96.

98. 98. The method of claim 97, wherein vision correction includes correcting hyperopia, correcting myopia, correcting astigmatism, or correcting presbyopia.

99. 98. The method of claim 97, wherein vision correction comprises slowing the progression of myopia.

100. 100. A method of treating presbyopia, comprising the step of applying to a patient's presbyopia a dynamic contact lens according to any one of claims 1 to 96.

101. A method of correcting the vision of a patient, comprising the step of applying to an eye of a patient in need of such treatment a dynamic contact lens according to any one of claims 1 to 96.

102. 102. The method of claim 101, wherein vision correction includes treating corneal irregularities or astigmatism.

103. 100. A method of treating an eye of a patient following an ocular therapy, comprising applying to the eye of a patient in need of such treatment a dynamic contact lens according to any one of claims 1 to 96.

104. 100. A method of healing a traumatic wound to the cornea of ​​a patient's eye, comprising the step of applying a dynamic contact lens according to any one of claims 1 to 96 to the patient's eye in need of such healing.

105. A method for protecting a patient's eye from potential injury, comprising the step of applying a dynamic contact lens according to any one of claims 1 to 96 to a patient's eye in need of such protection.

106. 1. A method of manufacturing a dynamic contact lens, comprising the steps of shaping a material to provide a dynamic contact lens, the contact lens comprising: a peripheral portion including a peripheral posterior surface and a peripheral anterior surface, the peripheral posterior surface including a peripheral base curve; and a dynamic portion including a dynamic posterior surface and a dynamic anterior surface, where at least the dynamic posterior surface bulges away from the peripheral base curve toward the dynamic anterior surface; method.

107. The peripheral portion includes a first material characterized by a first Young's modulus; and the dynamic portion includes a second material characterized by a second Young's modulus; 107. The method of claim 106, wherein each of the first Young's modulus and the second Young's modulus is between 0.05 MPa and 30 MPa.

108. 108. The method of claim 107, wherein each of the first Young's modulus and the second Young's modulus is between 0.1 MPa and 2 MPa.

109. 1. A method of making a dynamic contact lens comprising the steps of shaping a material to provide a dynamic contact lens, the dynamic contact lens comprising: A dynamic portion characterized by a dynamic base curve; and a periphery coupled to the dynamic portion; The method, wherein the periphery includes a peripheral base curve and the dynamic base curve is different from the peripheral base curve.

110. 110. The method of claim 109, wherein the radius of the base curve of the dynamic portion is less than the radius of the base curve of the peripheral portion.

111. 110. The method of claim 109, wherein the radius of curvature of the dynamic portion is less than the radius of curvature of the quasi-central periphery, the quasi-central periphery being adjacent to the dynamic portion.

112. A dynamic contact lens according to any one of claims 1 to 96, applied to the cornea.

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