Aspherical intraocular lens, design method for the same, and production method for the same

Abstract

To provide an intraocular lens which is robust in terms of changes in image quality in response to changes in displacement, tilt, and pupil diameter.SOLUTION: Provided is an intraocular lens comprising a power profile V that falls within a power profile convergence region which is obtained from each combination of power profiles Va and Vb when a position ra is defined as an intersection on a horizontal axis between the power profile Va and the power profile Vb. The power profile Va for a first region is obtained by adding, to a vertical axis value at each horizontal axis value of an aspherical reference power profile W, a value obtained by multiplying, by a prescribed percentage α (where α is 10% or more and 50% or less), a value obtained by subtracting, from a base power, the vertical axis value at each horizontal axis value of the aspherical reference power profile W. The power profile Vb for a second region is obtained by adding, to the horizontal axis value at each vertical axis value of the aspherical reference power profile W, a value obtained by multiplying, by a prescribed percentage β (where β is 10% or more and 50% or less), a value obtained by subtracting, from the maximum value rmax of the horizontal axis of the aspherical reference power profile W, the horizontal axis value at each vertical axis value of the aspherical reference power profile W.SELECTED DRAWING: Figure 2

Description

[Technical Field]

[0001] The present invention relates to an aspheric intraocular lens, a method for designing the same, and a method for manufacturing the same. [Background technology]

[0002] Intraocular lenses are known to play a role in correcting vision after the removal of a cloudy lens due to cataracts. For example, when the lens becomes cloudy due to cataracts, vision can be restored by surgically inserting an artificial intraocular lens into the lens capsule to replace the cloudy lens.

[0003] In

[0007] of Patent Document 1, it is stated that the objective is to obtain an intraocular lens that maintains the advantage of conventional aberration-reducing intraocular lenses, that is, the ability to see images clearly, while minimizing the decrease in contrast even when the optical axis of the intraocular lens is misaligned with the optical axis of the eyeball when inserted into the eye.

[0004] In order to solve this problem, Patent Document 1, etc., describes that when a power distribution set to cancel out the spherical aberration of the cornea when the intraocular lens is inserted into the eye is taken as a reference power distribution, the region near the center of this intraocular lens has a power distribution that includes at least one positive power deviation region, which is a region having a power greater than the power represented by the reference power distribution, and at least one negative power deviation region, which is a region having a power less than the power represented by the reference power distribution, thereby reducing the decrease in contrast that occurs when the optical axis of the intraocular lens inserted into the eye deviates from the optical axis of the eyeball.

[0005] Other known intraocular lenses include:

[0006] For example, Patent Documents 2 and 3 propose intraocular lenses that do not add new spherical aberration to the existing spherical aberration of the cornea (Claim 1 of Patent Document 2, Claim 1 of Patent Document 3). With these intraocular lenses, the power value is constant throughout the entire optical zone. Because no spherical aberration is added to the ocular optical system, there is no effect of image quality degradation due to lens displacement and tilt.

[0005] of Patent Document 2 proposes an aspherical intraocular lens in which the amount of negative spherical aberration is less than the amount required to offset the positive spherical aberration of the cornea.

[0007] Patent Document 4 proposes an aspherical intraocular lens that reduces the spherical aberration of the cornea of ​​an average human eye in order to minimize the spherical aberration of the optical eye system (claims 1, 13, etc. of Patent Document 4). The power value of such an aspherical intraocular lens decreases as the radius of the lens increases. In order for this lens to provide high image quality, it is necessary to keep the lens displacement and tilt low in aphakic patients.

[0008] Patent Document 5 proposes an aspheric intraocular lens that can balance image contrast and depth of focus within an acceptable range, especially under conditions of a large pupil (for example, 4.5 to 5 mm) (Claim 1 of Patent Document 5).

[0009] Patent Document 6 proposes an aspheric intraocular lens that provides minimal sensitivity of optical performance under the occurrence of lens concentration and lens tilt. The power value of the lens first decreases and then increases as the lens radius increases (black circles in Figure 6 of Patent Document 6). [Prior art documents] [Patent documents]

[0010] [Patent Document 1] Japanese Patent Application Laid-Open No. 2007-330478 [Patent Document 2] US2005 / 0203619 publication [Patent Document 3] WO2004 / 090611 publication [Patent Document 4] US2004 / 0088050 publication [Patent Document 5] WO2006 / 060477 publication [Patent Document 6] WO2007 / 128423 publication Summary of the Invention [Problem to be solved by the invention]

[0011] After an intraocular lens is inserted into the eye, it is possible that the center of the optical axis of the intraocular lens may become decentralized from the center of the cornea, or that the optical axis of the intraocular lens may become tilted from the thickness direction of the cornea (the direction of the eye axis).

[0012] Furthermore, it is expected that a wearer with an intraocular lens inserted will work outdoors in bright light and indoors in relatively dark places, which means that the diameter of the wearer's pupils may change.

[0013] An object of the present invention is to provide an intraocular lens and related art that can maintain good image quality while being robust in terms of changes in image quality with respect to the above-mentioned displacement, tilt, and pupil diameter. [Means for solving the problem]

[0014] The first aspect is An intraocular lens having at least two areas for vision correction that are concentric and adjacent to each other with a lens center O having a predetermined base power set thereto, The vision correction area is set in order from a first area including the lens center O toward the radially outward side, and a second area surrounding the first area is set; In a power profile in which the horizontal axis (unit: mm) represents the position when viewed in the radial direction from the lens center O, and the vertical axis (unit: D (diopter)) represents the power, when the position of the first boundary between the first region and the second region when viewed in the radial direction from the lens center O is set to r1, and When the power profile of a hypothetical aspheric lens that has a base power at the lens center O and completely offsets the positive vertical spherical aberration caused by the cornea is defined as an aspheric reference power profile W, a power profile Va for the first region obtained by adding a value obtained by subtracting the vertical axis value at each horizontal axis value of the aspherical reference power profile W from the base power and multiplying the result by a predetermined ratio α (α is 10% or more and 50% or less) to the vertical axis value at each horizontal axis value of the aspherical reference power profile W; a power profile Vb for the second region obtained by adding a value obtained by subtracting the horizontal axis value at each vertical axis value of the aspherical reference power profile W from the maximum value rmax of the horizontal axis of the aspherical reference power profile W by a predetermined ratio β (β is 10% or more and 50% or less) to the horizontal axis value at each vertical axis value of the aspherical reference power profile W; The intraocular lens has a power profile V that falls within the collection area of ​​power profiles obtained by combining the power profiles Va and Vb when the intersection of the power profiles Va and Vb is positioned at ra on the horizontal axis.

[0015] The second aspect is In the intraocular lens according to the first aspect, r1 is a value within the range of 1.5 mm or more and 2.3 mm or less.

[0016] The third aspect is This is an intraocular lens described in the first aspect, in which, at each horizontal axis value of the power profile V, the maximum positive value among the values ​​obtained by subtracting the vertical axis value of the aspherical reference power profile W from the vertical axis value of the power profile V is at position r1.

[0017] The fourth aspect is The intraocular lens according to the first aspect, wherein the maximum value rmax on the horizontal axis of the power profile V is a value within the range of 2.5 mm or more and 3.5 mm or less.

[0018] The fifth aspect is one or more additional regions radially outward from the second region; The additional region surrounds the second region; An intraocular lens according to the first aspect, wherein at each horizontal axis value of the power profile Vadd in at least one of the additional regions, the value obtained by subtracting the vertical axis value of the aspheric reference power profile W from the vertical axis value of the power profile Vadd is less than ±0.30D.

[0019] The sixth aspect is The intraocular lens according to the first aspect, wherein the power profile V is expressed by a polynomial.

[0020] A seventh aspect is one or more additional regions radially outward from the second region; The additional region surrounds the second region; The additional region is an intraocular lens according to the first aspect, which has a function of refracting incident light beams onto the retina.

[0021] The eighth aspect is An intraocular lens having at least two areas for vision correction that are concentric and adjacent to each other with a lens center O having a predetermined base power set thereto, The vision correction area is set in order from a first area including the lens center O toward the radially outward side, and a second area surrounding the first area is set; In a power profile in which the horizontal axis (unit: mm) represents the position when viewed in the radial direction from the lens center O, and the vertical axis (unit: D (diopter)) represents the power, when the position of the first boundary between the first region and the second region when viewed in the radial direction from the lens center O is set to r1, and When the power profile of a hypothetical aspheric lens that has a base power at the lens center O and completely offsets the positive vertical spherical aberration caused by the cornea is defined as an aspheric reference power profile W, In the first region, the average value of the vertical axis values ​​of the power profile V1 for the first region is greater than the average value of the vertical axis values ​​of the aspherical reference power profile W, In the second region, the average value of the vertical axis values ​​of the power profile V2 for the second region is greater than the average value of the vertical axis values ​​of the aspherical reference power profile W, In the power profile V1 for the first area, as the horizontal axis value increases, at each horizontal axis value, the value obtained by subtracting the vertical axis value of the aspheric reference power profile W from the vertical axis value of the power profile V1 increases continuously, In the power profile V2 for the second area, as the horizontal axis value increases, at each horizontal axis value, the value obtained by subtracting the vertical axis value of the aspheric reference power profile W from the vertical axis value of the power profile V2 continuously decreases, In the power profile V, the position r1 is the maximum positive value among the values ​​obtained by subtracting the vertical axis value of the aspheric reference power profile W from the vertical axis value of the power profile V2, This is an intraocular lens in which the value obtained by subtracting the vertical axis value of the aspheric reference power profile W from the vertical axis value at the maximum value rmax of the horizontal axis of the power profile V is less than 0.25D.

[0022] A ninth aspect is An intraocular lens according to an eighth aspect, wherein the absolute value of the average value of the tangent slope of the power profile V2 in the second region is three times or more the absolute value of the average value of the tangent slope of the power profile V1 in the first region.

[0023] A tenth aspect is In the intraocular lens according to the eighth aspect, r1 is a value within the range of 1.5 mm or more and 2.3 mm or less.

[0024] An eleventh aspect is The intraocular lens according to the eighth aspect, wherein the maximum value rmax on the horizontal axis of the power profile V is within the range of 2.5 mm or more and 3.5 mm or less.

[0025] A twelfth aspect is a power profile Va for the first region obtained by adding a value obtained by subtracting the vertical axis value at each horizontal axis value of the aspherical reference power profile W from the base power and multiplying the result by a predetermined ratio α (α is 10% or more and 50% or less) to the vertical axis value at each horizontal axis value of the aspherical reference power profile W; a power profile Vb for the second region obtained by adding a value obtained by subtracting the horizontal axis value at each vertical axis value of the aspherical reference power profile W from the maximum value rmax of the horizontal axis of the aspherical reference power profile W by a predetermined ratio β (β is 10% or more and 50% or less) to the horizontal axis value at each vertical axis value of the aspherical reference power profile W; The intraocular lens according to the eighth aspect has a power profile V that falls within the collection area of ​​the power profiles obtained by combining the power profiles Va and Vb when the intersection of the power profiles Va and Vb is positioned at position ra on the horizontal axis.

[0026] A thirteenth aspect is one or more additional regions radially outward from the second region; The additional region surrounds the second region; An intraocular lens according to an eighth aspect, wherein at each horizontal axis value of the power profile Vadd in at least one of the additional regions, the value obtained by subtracting the vertical axis value of the aspherical reference power profile W from the vertical axis value of the power profile Vadd is less than ±0.30D.

[0027] A fourteenth aspect is The intraocular lens according to an eighth embodiment, wherein the power profile V is expressed by a polynomial.

[0028] A fifteenth aspect is one or more additional regions radially outward from the second region; The additional region surrounds the second region; The additional region is an intraocular lens according to the eighth aspect, which has a function of refracting incident light beams onto the retina.

[0029] A sixteenth aspect is An intraocular lens having at least two areas for vision correction that are concentric and adjacent to each other with a lens center O having a predetermined base power set thereto, The vision correction areas are set in the order from a first area including the lens center O to an outer side in the radial direction, to an intermediate area surrounding the first area and a second area surrounding the intermediate area, In the power profile, the horizontal axis (unit: mm) represents the position when viewed radially from the lens center O, and the vertical axis represents the power (unit: D (diopter)). When the power profile of a hypothetical aspheric lens that has a base power at the lens center O and completely offsets the positive vertical spherical aberration caused by the cornea is defined as an aspheric reference power profile W, a power profile Va for the first region obtained by adding a value obtained by subtracting the vertical axis value at each horizontal axis value of the aspherical reference power profile W from the base power and multiplying the result by a predetermined ratio α (α is 10% or more and 50% or less) to the vertical axis value at each horizontal axis value of the aspherical reference power profile W; a power profile Vb for the second region obtained by adding a value obtained by subtracting the horizontal axis value at each vertical axis value of the aspherical reference power profile W from the maximum value rmax of the horizontal axis of the aspherical reference power profile W by a predetermined ratio β (β is 10% or more and 50% or less) to the horizontal axis value at each vertical axis value of the aspherical reference power profile W; A power profile Vmid for an intermediate region, the average power of which is smaller than the average power in the first region and larger than the average power in the second region; The intraocular lens has a power profile V that falls within a collection area of ​​power profiles obtained by combining the power profiles Va, Vmid, and Vb.

[0030] A seventeenth aspect is An intraocular lens according to a sixteenth aspect, wherein the absolute value of the average value of the tangent slope of the power profile Vmid in the intermediate region is greater than the absolute value of the average value of the tangent slope of the power profile V1 in the first region and is smaller than the absolute value of the average value of the tangent slope of the power profile V2 in the second region.

[0031] An eighteenth aspect is At each horizontal axis value of the power profile Vmid in the intermediate region, the average value of the value obtained by subtracting the vertical axis value of the aspheric reference power profile W from the vertical axis value of the power profile Vmid is At each horizontal axis value of the power profile V1 in the first region, the horizontal axis value is greater than the average value of the value obtained by subtracting the vertical axis value of the aspherical reference power profile W from the vertical axis value of the power profile V1, and This is an intraocular lens according to the sixteenth aspect, in which each horizontal axis value of the power profile V2 in the second region is greater than the average value of the value obtained by subtracting the vertical axis value of the aspherical reference power profile W from the vertical axis value of the power profile V2.

[0032] A nineteenth aspect is The intermediate region is an intraocular lens according to the sixteenth aspect, in which the horizontal axis value is within the range of 1.3 mm or more and 2.5 mm or less.

[0033] The twentieth aspect is The intraocular lens according to the sixteenth aspect, wherein the maximum value rmax on the horizontal axis of the power profile V is within the range of 2.5 mm or more and 3.5 mm or less.

[0034] A twenty-first aspect is An intraocular lens according to a sixteenth aspect, wherein the absolute value of the average value of the tangent slope of the power profile V2 in the second region is three or more times the absolute value of the average value of the tangent slope of the power profile V1 in the first region.

[0035] A twenty-second aspect is one or more additional regions radially outward from the second region; The additional region surrounds the second region; An intraocular lens according to a sixteenth aspect, wherein at each horizontal axis value of the power profile Vadd in at least one of the additional regions, the value obtained by subtracting the vertical axis value of the aspheric reference power profile W from the vertical axis value of the power profile Vadd is less than ±0.30D.

[0036] A twenty-third aspect is The intraocular lens according to a sixteenth aspect, wherein the power profile V is expressed by a polynomial.

[0037] A twenty-fourth aspect is one or more additional regions radially outward from the second region; The additional region surrounds the second region; The additional region is an intraocular lens according to the sixteenth aspect, which has a function of refracting incident light beams onto the retina.

[0038] The 25th aspect is An intraocular lens having at least two areas for vision correction that are concentric and adjacent to each other with a lens center O having a predetermined base power set thereto, The vision correction area is set in order from a first area including the lens center O toward the radially outward side, and a second area surrounding the first area is set; When the power profile of a hypothetical aspheric lens that has a base power at the lens center O and completely offsets the positive vertical spherical aberration caused by the cornea is defined as an aspheric reference power profile W, In a total power profile where the horizontal axis (unit: mm) represents the position when viewed in the radial direction from the lens center O, and the vertical axis (unit: D (diopter)) represents the total power T when the refractive power of the cornea and the power of the intraocular lens are added together, when the position of the first boundary between the first region and the second region when viewed in the radial direction from the lens center O is set to r1, a total power profile TVa for the first region obtained by subtracting the vertical axis value at each horizontal axis value of the aspherical reference total power profile TW, to which the refractive power of the cornea has been added, from the base power, and multiplying the result by a predetermined ratio α (α is 10% or more and 50% or less), and adding the result to the vertical axis value at each horizontal axis value of the aspherical reference total power profile TW; a total power profile TVb for the second region obtained by subtracting the horizontal axis value at each vertical axis value of the aspherical reference total power profile TW, to which the refractive power of the cornea has been added, from the maximum value rmax of the horizontal axis of the aspherical reference total power profile TW, and multiplying the result by a predetermined ratio β (β is 10% or more and 50% or less), and adding the obtained value to the horizontal axis value at each vertical axis value of the aspherical reference total power profile TW; The intraocular lens has a total power profile TV that falls within the aggregate area of ​​the total power profiles obtained by combining the total power profiles TVa and TVb when the intersection of the above is positioned at ra on the horizontal axis.

[0039] A twenty-sixth aspect is In the total power profile TV1 for the first region, the vertical axis value increases continuously as the horizontal axis value increases, This is an intraocular lens according to the 25th aspect, in which in the total power profile TV2 for the second region, the vertical axis value continuously decreases as the horizontal axis value increases.

[0040] A twenty-seventh aspect is The absolute value of the average value of the slope of the tangent of the total power profile TV1 near the origin in the first region is smaller than the absolute value of the average value of the slope of the tangent of the total power profile TV1 near the intermediate position in the first region; the absolute value of the average value of the slope of the tangent of the total power profile TV1 in the vicinity of the intermediate position in the first region is greater than the absolute value of the average value of the slope of the tangent of the total power profile TV1 in the vicinity of the position r1 in the first region; An intraocular lens according to a 25th aspect, wherein the absolute value of the average value of the tangent slope of the total power profile TV1 near position r1 in the first region is smaller than the absolute value of the average value of the tangent slope of the total power profile TV2 near the intermediate position in the second region.

[0041] A twenty-eighth aspect is In the total power profile TV, the value obtained by subtracting the vertical axis value at r=0 from the vertical axis value at position r1 is the maximum positive value, In the intraocular lens according to the twenty-fifth aspect, r1 is a value within the range of 1.5 mm or more and 2.3 mm or less.

[0042] A twenty-ninth aspect is An intraocular lens according to the 25th aspect, wherein the value obtained by subtracting the vertical axis value at r=0 from the vertical axis value at the maximum value rmax of the horizontal axis of the total power profile TV is less than ±0.30D.

[0043] A thirtieth aspect is The intraocular lens according to the 25th aspect, wherein the maximum value rmax on the horizontal axis of the total power profile TV is within the range of 2.5 mm or more and 3.5 mm or less.

[0044] A thirty-first aspect is one or more additional regions radially outward from the second region; The additional region surrounds the second region; The additional region is an intraocular lens according to the 25th aspect, which has the function of refracting incident light beams onto the retina.

[0045] A thirty-second aspect is An intraocular lens having at least two areas for vision correction that are concentric and adjacent to each other with a lens center O having a predetermined base power set thereto, The vision correction area is set in order from a first area including the lens center O toward the radially outward side, and a second area surrounding the first area is set; In the power profile, the horizontal axis (unit: mm) represents the position when viewed radially from the lens center O, and the vertical axis represents the power (unit: D (diopter)). The power profile of a hypothetical aspheric lens that has a base power at the lens center O and completely offsets the positive vertical spherical aberration caused by the cornea is defined as an aspheric reference power profile W, a power profile obtained by adding a value obtained by subtracting the vertical axis value at each horizontal axis value of the aspherical reference power profile W from the base power and multiplying the result by a predetermined ratio α (α is 10% or more and 50% or less) to the vertical axis value at each horizontal axis value of the aspherical reference power profile W is defined as a power profile Va for the first region; When a power profile Vb for the second region is a power profile obtained by adding a value obtained by subtracting the horizontal axis value at each vertical axis value of the aspherical reference power profile W from the maximum value rmax of the horizontal axis of the aspherical reference power profile W by a predetermined ratio β (β is 10% or more and 50% or less) to the horizontal axis value at each vertical axis value of the aspherical reference power profile W, The first region includes an inner first region having a power profile in which a positive power is added to a power profile Va for the first region, the second region has a power profile Vb; The intraocular lens has an area of ​​the inner first region that is less than 50% of the total area of ​​the first region.

[0046] A thirty-third aspect is When viewed in a radial direction from a lens center O, the first region includes an inner first region and an outer first region surrounding the inner first region, The intraocular lens according to the thirty-second aspect, wherein the outer first region has a power profile Va and is in contact with the second region at the intersection of the power profiles Va and Vb.

[0047] A thirty-fourth aspect is An intraocular lens according to a thirty-second aspect, wherein the lens body of the intraocular lens has two opposing surfaces and the inner first region is provided on the front surface, the rear surface, or both.

[0048] The thirty-fifth aspect is The intraocular lens according to the 32nd aspect, wherein the first region includes a region other than the inner first region whose average power is equal to the average power of the power profile Va, and the average power of the inner first region is 0.75 to 4.0 D greater than the average power of the region other than the inner first region.

[0049] A thirty-sixth aspect is The intraocular lens of the thirty-third aspect, wherein the first region comprises an outer transition region for connecting the inner first region to the outer first region.

[0050] A thirty-seventh aspect is the inner first region includes a constant power addition region having a power profile in which a positive constant power is added to the power profile Va for the first region; In the intraocular lens according to the thirty-second aspect, when viewed in the radial direction from the lens center O, the radial distance of the fixed power addition region is 33 to 67% of the radial distance of the inner first region.

[0051] A thirty-eighth aspect is The intraocular lens according to the thirty-second aspect, wherein the inner first region includes the lens center O.

[0052] A thirty-ninth aspect is the first region includes an innermost region having a power profile Va for the first region and including a lens center O; The intraocular lens according to the thirty-third aspect, wherein the inner first region surrounds the innermost region.

[0053] The fortieth aspect is The intraocular lens of a thirty-ninth aspect, wherein the first region comprises an inner transition region for connecting the inner first region to the innermost region.

[0054] The forty-first aspect is The intraocular lens according to the thirty-second aspect, wherein the front surface, the rear surface, or both of the lens body of the intraocular lens having two opposing surfaces are aspherical.

[0055] The forty-second aspect is The intraocular lens according to the thirty-second aspect has a lens body having two opposing surfaces, and the front surface, the rear surface, or both of the lens body has a toric surface with a cylindrical power for correcting astigmatism in an aphakic patient.

[0056] The lens surface that is turned (formed) into an aspheric surface to achieve (create) the power profile taught by the disclosure of this application (the present specification) may be the front surface only, the back surface only, or both the front and back surfaces (both surfaces).

[0057] The forty-third aspect is The intraocular lens according to any one of the first to forty-second aspects is made of at least one of silicone, hydrophobic acrylic resin, hydrophilic acrylic resin, hydrogel, PMMA, PMMA copolymer, and collagen-containing HEMA (hydroxyethyl methacrylate) copolymer.

[0058] The forty-fourth aspect is A method for designing an intraocular lens, for designing the intraocular lens according to any one of the first to forty-second aspects.

[0059] The forty-fifth aspect is A method for manufacturing an intraocular lens, in which an intraocular lens designed by the method for designing an intraocular lens according to the 44th aspect is manufactured by at least one of lathing, molding, and 3D printing.

[0060] Other aspects of the present invention are listed below.

[0061] The area ratio between the first region and the second region in a plan view may be set to a value between 25:75 and 75:25.

[0062] In the first region, the power preferably decreases continuously. In the second region, the power preferably decreases continuously.

[0063] Between the lens center O and the position r1 of the first boundary, it is preferable that the total power T obtained by adding the refractive power of the cornea and the power of the intraocular lens increases continuously.

[0064] The technical concept of the present invention can also be applied to a method for designing or manufacturing an intraocular lens. [Effects of the Invention]

[0065] According to the present invention, the image quality remains good and is robust against changes in the image quality with respect to the above-mentioned displacement, tilt, and pupil diameter. [Brief explanation of the drawings]

[0066] [Figure 1] FIG. 1 is a schematic plan view showing an intraocular lens according to an embodiment of the present invention. [Figure 2] FIG. 2 is a power profile in which the horizontal axis (unit: mm) represents the position when viewed in the radial direction from the lens center O, and the vertical axis represents the power (unit: D (diopter)). [Figure 3]Figure 3 is a power profile showing the refractive power (vertical axis) provided by the optical part of the intraocular lens versus the distance from the lens center O (horizontal axis), and is a diagram showing a power profile Va obtained by subtracting the vertical axis value at each horizontal axis value of the aspherical reference power profile W from the base power and multiplying the result by a predetermined percentage α (α is 10% or more and 35% or less, i.e., I10, 35% or I35, and 50% or I50) to obtain a value, and adding the result to the vertical axis value at each horizontal axis value of the aspherical reference power profile W. [Figure 4] Figure 4 is a power profile showing the refractive power (vertical axis) provided by the optical part of the intraocular lens versus the distance from the lens center O (horizontal axis), and is a diagram showing a power profile Vb obtained by adding the value obtained by subtracting the horizontal axis value at each vertical axis value of the aspherical reference power profile W from the maximum value rmax of the horizontal axis of the aspherical reference power profile W by a predetermined ratio β (β is a value between 10% and 50%, where 10% is O10, 25% is O25, and 50% is O50) to the horizontal axis value at each vertical axis value of the aspherical reference power profile W. [Figure 5] FIG. 5 is an explanatory diagram of I35 in FIG. 3 and O25 in FIG. 4 superimposed on each other. [Figure 6] FIG. 6 is a diagram showing a power profile V obtained by joining together the power profile Va (I35) for the first region and the power profile Vb (O25) for the second region in FIG. [Figure 7] FIG. 7 is a diagram showing I10-O10, I40-O20, and I50-O50. [Figure 8] Figure 8 shows the area (hatched portion) composed of the power profile when the intersection of the power profile Va for the first area (α is 10% or more and 50% or less) and the power profile Vb for the second area (β is 10% or more and 50% or less) is set at position ra on the horizontal axis. [Figure 9] FIG. 9 is a diagram showing a power profile V (solid line) obtained when, in an [Other] embodiment of the present invention, different power profiles are not directly patched together, but a profile that imitates the patched-together profile is used. [Figure 10]FIG. 10 is a diagram showing a power profile V (solid line, I35-O25, optical zone diameter 6.50 mm) when an additional region is provided. [Figure 11] Figure 11 is a diagram showing I10-O10 and I50-O50, and also shows, for each power profile V, the average value of the tangent slope of the power profile V1 in the first region and the absolute value of the average value of the tangent slope of the power profile V2 in the second region. [Figure 12A] FIG. 12A is a diagram showing a power profile V (solid line, I35-O25) when an intermediate region is provided. [Figure 12B] FIG. 12B is a diagram showing the intermediate region of FIG. 12A expanded. [Figure 12C] FIG. 12C is a diagram showing a power profile V (solid line, I40-O40) when an intermediate region is provided. [Figure 13] FIG. 13 is a table showing conditions employed in the total power profile according to the embodiment of the present invention. [Figure 14] FIG. 14 is a total power profile TV showing the total power T (vertical axis) when the refractive power of the cornea and the power of the intraocular lens are combined, versus the distance from the lens center O (horizontal axis). [Figure 15] FIG. 15 is a diagram showing the total power profile TV when the horizontal axis value rmax of 3.0 mm is matched with the vertical axis value when the horizontal axis value is zero. [Figure 16] Figure 16 shows the area (hatched portion) composed of the total power profile when the intersection of the total power profile TVa for the first area (α is 10% or more and 50% or less) and the total power profile TVb for the second area (β is 10% or more and 50% or less) is set at position ra on the horizontal axis. [Figure 17A]FIG. 17A is a plot showing the MTF value (vertical axis) indicating contrast against the object distance (horizontal axis) from the corneal apex (aperture diameter (pupil diameter) is set to 3.0 mm, and there is no displacement or tilt). The MTF values ​​shown in FIGS. 17 to 30 are MTF values ​​when the spatial frequency is 100 lines / mm. The spatial frequency of the MTF value (vertical axis) is 100 lines / mm. [Figure 17B] FIG. 17B shows the same configuration as FIG. 17A except that the aperture diameter is set to 3.5 mm. [Figure 17C] FIG. 17C shows the same configuration as FIG. 17A except that the aperture diameter is set to 4.0 mm. [Figure 17D] FIG. 17D shows the same configuration as FIG. 17A except that the aperture diameter is set to 4.5 mm. [Figure 18A] Figure 18A is a plot showing the MTF value (vertical axis) indicating contrast against the object distance (horizontal axis) from the corneal apex (aperture diameter (pupil diameter) set to 3.0 mm, displacement 0.3 mm, no tilt). [Figure 18B] FIG. 18B shows the same configuration as FIG. 18A except that the aperture diameter is set to 3.5 mm. [Figure 18C] FIG. 18C shows the same configuration as FIG. 18A except that the aperture diameter is set to 4.0 mm. [Figure 18D] FIG. 18D shows the same configuration as FIG. 18A except that the aperture diameter is set to 4.5 mm. [Figure 19A] FIG. 19A is a plot showing the MTF value (vertical axis) indicating contrast against the object distance (horizontal axis) from the corneal apex (aperture diameter (pupil diameter) set to 3.0 mm, displacement 0.5 mm, no tilt). [Figure 19B] FIG. 19B shows the same configuration as FIG. 19A except that the aperture diameter is set to 3.5 mm. [Figure 19C] FIG. 19C is a diagram in which the aperture diameter in FIG. 19A is set to 4.0 mm. [Figure 19D] FIG. 19D shows the same configuration as FIG. 19A except that the aperture diameter is set to 4.5 mm. [Figure 20A] Figure 20A is a plot showing the MTF value (vertical axis) indicating contrast against the object distance (horizontal axis) from the corneal apex (aperture diameter (pupil diameter) set to 3.0 mm, no displacement, and a tilt of 3 degrees). [Figure 20B] FIG. 20B shows the same configuration as FIG. 20A except that the aperture diameter is set to 3.5 mm. [Figure 20C] FIG. 20C is a diagram in which the aperture diameter in FIG. 20A is set to 4.0 mm. [Figure 20D] FIG. 20D shows the same configuration as FIG. 20A except that the aperture diameter is set to 4.5 mm. [Figure 21A] Figure 21A is a plot showing the MTF value (vertical axis) indicating contrast against the object distance (horizontal axis) from the corneal apex (aperture diameter (pupil diameter) set to 3.0 mm, no displacement, and a tilt of 5 degrees). [Figure 21B] FIG. 21B shows the same configuration as FIG. 21A except that the aperture diameter is set to 3.5 mm. [Figure 21C] FIG. 21C shows the same configuration as FIG. 21A except that the aperture diameter is set to 4.0 mm. [Figure 21D] FIG. 21D shows the same situation as in FIG. 21A, except that the aperture diameter is set to 4.5 mm. [Figure 22A] Figure 22A is a plot showing the MTF value (vertical axis) indicating contrast against the object distance (horizontal axis) from the corneal apex (aperture diameter (pupil diameter) set to 3.0 mm, displacement 0.3 mm, tilt 3 degrees). [Figure 22B] FIG. 22B shows the same configuration as FIG. 22A except that the aperture diameter is set to 3.5 mm. [Figure 22C] FIG. 22C is a diagram in which the aperture diameter in FIG. 22A is set to 4.0 mm. [Figure 22D] FIG. 22D shows the same configuration as FIG. 22A except that the aperture diameter is set to 4.5 mm. [Figure 23A]Figure 23A is a plot showing the MTF value (vertical axis) indicating contrast against the object distance (horizontal axis) from the corneal apex (aperture diameter (pupil diameter) set to 3.0 mm, displacement 0.4 mm, tilt 4 degrees). [Figure 23B] FIG. 23B shows the same configuration as FIG. 23A except that the aperture diameter is set to 3.5 mm. [Figure 23C] FIG. 23C is a diagram in which the aperture diameter in FIG. 23A is set to 4.0 mm. [Figure 23D] FIG. 23D shows the same configuration as FIG. 23A except that the aperture diameter is set to 4.5 mm. [Figure 24A] Figure 24A is a plot showing the MTF value (vertical axis) indicating contrast against the object distance (horizontal axis) from the corneal apex (aperture diameter (pupil diameter) set to 3.0 mm, displacement 0.5 mm, tilt 5 degrees). [Figure 24B] FIG. 24B shows the same configuration as FIG. 24A except that the aperture diameter is set to 3.5 mm. [Figure 24C] FIG. 24C shows the same configuration as FIG. 24A except that the aperture diameter is set to 4.0 mm. [Figure 24D] FIG. 24D shows the same configuration as FIG. 24A except that the aperture diameter is set to 4.5 mm. [Figure 25A] FIG. 25A is a plot showing the MTF value (vertical axis) indicating contrast against the displacement (horizontal axis) (object distance set to 2.0 m, aperture diameter (pupil diameter) set to 3.0 mm, and no slope). [Figure 25B] FIG. 25B is a diagram in which the inclination in FIG. 25A is set to 3 degrees. [Figure 25C] FIG. 25C is a diagram in which the inclination in FIG. 25A is set to 5 degrees. [Figure 25D] FIG. 25D is a diagram in which the aperture diameter in FIG. 25A is set to 4.0 mm and there is no tilt. [Figure 25E] FIG. 25E is a diagram in which the aperture diameter in FIG. 25A is set to 4.0 mm and the inclination is set to 3 degrees. [Figure 25F] FIG. 25F shows the same configuration as FIG. 25A except that the aperture diameter is set to 4.0 mm and the inclination is set to 5 degrees. [Figure 26A] FIG. 26A is a plot showing the MTF value (vertical axis) indicating contrast against the displacement (horizontal axis) (object distance set to 3.0 m, aperture diameter (pupil diameter) set to 3.0 mm, and no slope). [Figure 26B] FIG. 26B is a diagram in which the inclination in FIG. 26A is set to 3 degrees. [Figure 26C] FIG. 26C is a diagram in which the inclination in FIG. 26A is set to 5 degrees. [Figure 26D] FIG. 26D is a diagram in which the aperture diameter in FIG. 26A is set to 4.0 mm and there is no tilt. [Figure 26E] FIG. 26E is a diagram in which the aperture diameter in FIG. 26A is set to 4.0 mm and the inclination is set to 3 degrees. [Figure 26F] FIG. 26F is a diagram in which the aperture diameter in FIG. 26A is set to 4.0 mm and the inclination is set to 5 degrees. [Figure 27A] FIG. 27A is a plot showing the MTF value (vertical axis) indicating contrast against the displacement (horizontal axis) (object distance set to 4.0 m, aperture diameter (pupil diameter) set to 3.0 mm, and no tilt). [Figure 27B] FIG. 27B is a diagram in which the inclination in FIG. 27A is set to 3 degrees. [Figure 27C] FIG. 27C shows the same as FIG. 27A except that the inclination is set to 5 degrees. [Figure 27D] FIG. 27D is a diagram in which the aperture diameter in FIG. 27A is set to 4.0 mm and there is no tilt. [Figure 27E] FIG. 27E is a diagram in which the aperture diameter in FIG. 27A is set to 4.0 mm and the inclination is set to 3 degrees. [Figure 27F] FIG. 27F shows the same situation as in FIG. 27A except that the aperture diameter is set to 4.0 mm and the inclination is set to 5 degrees. [Figure 28A]FIG. 28A is a plot showing the MTF value (vertical axis) indicating contrast against the tilt (horizontal axis) (object distance set to 2.0 m, aperture diameter (pupil diameter) set to 3.0 mm, and no displacement). [Figure 28B] FIG. 28B shows the same as FIG. 28A except that the displacement is set to 0.3 mm. [Figure 28C] FIG. 28C shows the same as FIG. 28A except that the displacement is set to 0.5 mm. [Figure 28D] FIG. 28D shows the same situation as in FIG. 28A except that the aperture diameter is set to 4.0 mm and there is no displacement. [Figure 28E] FIG. 28E shows the same situation as in FIG. 28A, except that the aperture diameter is set to 4.0 mm and the displacement is set to 0.3 mm. [Figure 28F] FIG. 28F shows the same situation as in FIG. 28A except that the aperture diameter is set to 4.0 mm and the displacement is set to 0.5 mm. [Figure 29A] FIG. 29A is a plot showing the MTF value (vertical axis) indicating contrast against the tilt (horizontal axis) (object distance set to 3.0 m, aperture diameter (pupil diameter) set to 3.0 mm, and no displacement). [Figure 29B] FIG. 29B shows the same as FIG. 29A except that the displacement is set to 0.3 mm. [Figure 29C] FIG. 29C shows the same as FIG. 29A except that the displacement is set to 0.5 mm. [Figure 29D] FIG. 29D shows the same situation as in FIG. 29A except that the aperture diameter is set to 4.0 mm and there is no displacement. [Figure 29E] FIG. 29E shows the same situation as in FIG. 29A, except that the aperture diameter is set to 4.0 mm and the displacement is set to 0.3 mm. [Figure 29F] FIG. 29F shows the same situation as in FIG. 29A except that the aperture diameter is set to 4.0 mm and the displacement is set to 0.5 mm. [Figure 30A]FIG. 30A is a plot showing the MTF value (vertical axis) indicating contrast against the tilt (horizontal axis) (object distance set to 4.0 m, aperture diameter (pupil diameter) set to 3.0 mm, and no displacement). [Figure 30B] FIG. 30B shows the same as FIG. 30A except that the displacement is set to 0.3 mm. [Figure 30C] FIG. 30C shows the same as FIG. 30A except that the displacement is set to 0.5 mm. [Figure 30D] FIG. 30D shows the same situation as in FIG. 30A except that the aperture diameter is set to 4.0 mm and there is no displacement. [Figure 30E] FIG. 30E is a diagram in which the aperture diameter in FIG. 30A is set to 4.0 mm and the displacement is set to 0.3 mm. [Figure 30F] FIG. 30F shows the same situation as in FIG. 30A except that the aperture diameter is set to 4.0 mm and the displacement is set to 0.5 mm. [Figure 31A] FIG. 31A is a schematic plan view showing an intraocular lens according to embodiment 5A of the present invention. [Figure 31B] FIG. 31B is a schematic plan view showing an intraocular lens according to embodiment 5B of the present invention. [Figure 32A] Figure 32A is a power profile for an intraocular lens of embodiment 5A of the present invention, with the horizontal axis (unit: mm) representing the position when viewed radially from the lens center O and the vertical axis representing the power (unit: D (diopter)). [Figure 32B] Figure 32B is a power profile for an intraocular lens of embodiment 5B of the present invention, with the horizontal axis (unit: mm) representing the position when viewed radially from the lens center O and the vertical axis representing the power (unit: D (diopter)). [Figure 33A] Figure 33A shows a schematic plan view (top) of an intraocular lens of embodiment 5A of the present invention having an outer transition region, and a power profile (bottom) in which the horizontal axis (unit: mm) represents the position when viewed radially from the lens center O, and the vertical axis (unit: D (diopter)) represents the power. [Figure 33B]Figure 33B shows a schematic plan view (top) of an intraocular lens of embodiment 5B of the present invention that has an inner transition region in addition to an outer transition region, and a power profile (bottom) in which the horizontal axis (unit: mm) represents the position when viewed radially from the lens center O and the vertical axis (unit: D (diopter)) represents the power. [Figure 34] Figure 34 is a power profile for an intraocular lens of embodiment 5A of the present invention, in which the horizontal axis (unit: mm) represents the position when viewed radially from the lens center O and the vertical axis (unit: D (diopter)) represents the power, and explains the ratio of the radial distance of the fixed power added region to the radial distance of the inner first region. DETAILED DESCRIPTION OF THE INVENTION

[0067] [Definition, etc.] Note that for configurations not described below, known configurations may be appropriately adopted. In particular, the contents (especially the support portion) described in a document (WO2009 / 153873) disclosed by the present inventor may be applied to this embodiment. In addition, in this specification, "to" indicates a value greater than or equal to a predetermined value and less than or equal to a predetermined value. Furthermore, the lens body of the intraocular lens discussed in this specification has two opposing surfaces. The surface of the lens body that comes into contact with the posterior capsule when the intraocular lens is inserted into the lens capsule can be referred to as the posterior surface, the retina-side surface, or the retina-side surface in the optical axis direction, but the term "posterior surface" will be used primarily in this specification. The other surface can be referred to as the anterior surface, the cornea-side surface, or the cornea-side surface in the optical axis direction, but the term "anterior surface" will be used primarily in this specification. The optical axis direction is also the lens thickness direction, and is the direction from the posterior surface to the anterior surface or the reverse direction. The optical axis direction is the z-axis direction.

[0068] The lens center O refers to the geometric center or optical center of the intraocular lens. In this specification, the case where the geometric center and the optical center coincide is illustrated. The refractive power at this lens center O is referred to as the base power. This base power refers to the refractive power required for distance vision in the conventional intraocular lens.

[0069] [Common embodiment] Hereinafter, embodiments of the present invention will be described in detail with reference to the drawings. First, the contents and inventive concepts common to the first and subsequent embodiments will be described as a common embodiment.

[0070] FIG. 1 is a schematic plan view showing an intraocular lens according to a common embodiment.

[0071] As shown in FIG. 1, an intraocular lens according to a common embodiment (and other aspects described herein) comprises, like a conventional intraocular lens, a lens body having a lens function and a support portion that supports the lens body within the lens capsule.

[0072] There are no limitations on the material of the intraocular lens, and it may be made of at least one of silicone, hydrophobic acrylic resin, hydrophilic acrylic resin, hydrogel, PMMA, PMMA copolymer, and copolymer of HEMA (hydroxyethyl methacrylate) containing collagen (e.g., Collamer (registered trademark)).

[0073] As shown in Figure 1, in the common embodiment (and other aspects described herein), the entire lens body is an optical part having a lens function. The "lens function" here refers to the function of refracting incident light beams onto the retina.

[0074] In this specification, the entire lens body is exemplified as consisting of a first region (zone 1) and a second region (zone 2) described below. In other embodiments described in this specification, an intermediate region surrounding the first region is provided between the first region and the second region, or an additional region surrounding the second region is provided radially outward of the second region.

[0075] In a common embodiment, the intraocular lens is defined by the refractive power (power, dioptric power) relative to the radial distance from the lens center O. In this specification, the "direction radially away from the lens center O" is defined as the "outside."

[0076] An intraocular lens according to a common embodiment (and other aspects described herein) first includes at least two adjacent regions for vision correction that are concentric with a lens center O and have a predetermined base power set thereto. The regions for vision correction are set in order from a first region including the lens center O toward the outside in the radial direction to a second region that surrounds the first region. The position of a first boundary (boundary 1) between the first region and the second region when viewed in the radial direction from the lens center O is set to r1.

[0077] As shown in Figure 1, in plan view, the first region is circular and the second region is annular. In other embodiments described herein, the intermediate region is a small annular ring, and the additional region is a large annular ring. Note that instead of a circular and / or annular shape, an elliptical and / or an elliptical annular shape may be used. In the case of an ellipse, the position r1 of the first boundary may be determined by the major axis or minor axis.

[0078] Figure 2 shows a power profile in which the horizontal axis (unit: mm) represents the position when viewed radially from the lens center O, and the vertical axis represents the power (unit: D (diopter)). The distance from the lens center O is also called the radius. The solid line is the power profile of an intraocular lens according to a common embodiment (and other aspects described herein). The dotted line represents the power profile of a virtual spherical lens (also referred to herein as a "spherical IOL") with a base power (dashed line) at the lens center O. Note that intraocular lenses with a constant power regardless of the value of the radius (horizontal axis) are well known (e.g., SofPort® AO IOL). This type of intraocular lens is also referred to herein as a "zero-aberration IOL." However, unlike the aspherical reference power profile W described below, a zero-aberration IOL does not take the cornea into account. In other words, the power profile of a zero-aberration IOL does not take into account the positive vertical spherical aberration or refractive power caused by the cornea. The dashed-dotted line represents the power profile of a hypothetical aspherical lens that has a base power at the lens center O and completely offsets the positive vertical spherical aberration caused by the cornea. This power profile is also referred to as the aspherical reference power profile W.

[0079] Longitudinal spherical aberration is spherical aberration in the direction extending radially from the lens center O, i.e., in the radial direction (meridional). In this case, spherical aberration in the circumferential direction (sagittal), which is perpendicular to the radial direction, is horizontal spherical aberration.

[0080] The cornea has positive refractive power. Spherical aberration increases with distance from the center of the cornea. In other words, the dashed-dotted line representing the aspherical reference power profile W is a plot of a hypothetical aspherical lens that theoretically offsets all of the positive vertical spherical aberration caused by the cornea. Hereinafter, the meanings of the various lines will be the same.

[0081] An aspheric optically designed IOL with an aspheric reference power profile W is designed to correct or reduce all or part of the corneal spherical aberration. The degree to which the corneal spherical aberration is reduced varies for each IOL manufactured by each company. Each IOL manufactured by each company is designed to reduce the corneal spherical aberration by a specific amount (value). In designing the aspheric IOL, a corneal model having a spherical aberration value equal to the specific amount of spherical aberration to be reduced is preset, and the specific amount of spherical aberration to be reduced by the aspheric IOL is determined by selecting the optical parameters of the corneal model. During the optical design process, the total spherical aberration of the optical system (optical system) consisting of the predetermined corneal model and the designed aspheric IOL is zero (i.e., there is no spherical aberration).

[0082] The spherical aberration value of the given corneal model is determined as follows: The spherical aberration value of the given corneal model used in the optical design of the aspheric IOL is assumed to be the same as the mean spherical aberration value for a population of eye patients wearing the IOL, or the spherical aberration value of the given corneal model is determined by setting the spherical aberration value to a value that partially reduces the corneal spherical aberration of the population of eye patients.

[0083] The aspheric reference power profile W is the power distribution of an aspheric IOL. This power distribution has the power distribution characteristic of being able to completely or partially reduce the spherical aberration of the average cornea (statistical corneal optical parameters) of a population of aphakic patients. In this specification, the spherical aberration value of a predetermined corneal model is set to 0.27 μm. Figure 2 is also an example of the power distribution of an aspheric IOL that can completely reduce the spherical aberration of a corneal model with a spherical aberration value of 0.27 μm. 0.27 μm may also be expressed as +0.27 μm. Furthermore, the present invention is not strictly limited to 0.27 μm, and may be, for example, a value in the range of +0.24 to +0.30 μm.

[0084] The following describes the inventive concept common to the first and subsequent embodiments.

[0085] To reiterate, the object of the present invention is to provide an intraocular lens and related technology that are robust in terms of changes in image quality against the above-mentioned changes in displacement, tilt, and pupil diameter (hereinafter collectively referred to as "each change"). "Robust" here also means being less susceptible to influence or insensitive.

[0086] While the aspheric IOLs can correct or reduce all or part of the corneal spherical aberration and still meet prescription values, the image quality is sensitive to these changes.

[0087] The image quality of spherical IOLs is more robust to changes compared to aspherical IOLs. However, in the absence of these changes, the image quality of spherical IOLs is inferior to that of aspherical IOLs. The difference in image quality becomes particularly pronounced when the pupil diameter increases.

[0088] The image quality of the zero-aberration IOL is more robust to changes in the above-mentioned variables than that of an aspheric IOL. However, the power profile of a zero-aberration IOL does not take into account the positive vertical spherical aberration or refractive power of the cornea. As a result, in the absence of these variables, the image quality of a zero-aberration IOL is slightly better than that of a spherical IOL, but is inferior to that of an aspheric IOL.

[0089] In the present invention, first, the aspherical reference power profile W of the aspherical IOL is taken as a whole as a reference. In the aspherical reference power profile W, as the horizontal axis value, which is the radial direction from the lens center O, increases, the vertical axis value, which is the power, decreases.

[0090] Here, the aspherical reference power profile W is divided into at least two regions. The side closer to the lens center O is the first region, and the outside of that is the second region. Then, the aspherical reference power profile W is deformed in each region.

[0091] In the first region, even when the horizontal axis value increases, the degree of decrease in the vertical axis value is made gentler than in the aspherical reference power profile W. To compensate for this, in the second region, when the horizontal axis value increases, the degree of decrease in the vertical axis value is made steeper than in the aspherical reference power profile W.

[0092] As shown in the data below, an intraocular lens that uses a power profile that is modified from the aspherical reference power profile W using this concept will maintain image quality as good as that of an aspherical IOL, while being robust against changes in image quality due to the changes mentioned above.

[0093] In other words, the concept of the present invention is to patch together two or more different power profiles rather than one power profile like the aspherical reference power profile W. The concept of the present invention is that when this patching is performed, the degree of decrease in the vertical axis value is made gentler in the first region when viewed as a whole than the aspherical reference power profile W, while the degree of decrease in the vertical axis value is made steeper in the second region when viewed as a whole than the aspherical reference power profile W.

[0094] The concept of the present invention also has the advantage of reducing the thickness of intraocular lenses. For example, the central thicknesses of a spherical IOL, a zero-aberration IOL, an aspheric IOL, and an IOL based on the concept of the present invention (see Figure 2 below) were measured under the following parameters. These parameters are also referred to as Condition 1. The radius of curvature of the posterior surface is negative because the anterior surface is convex and the curvature direction of the convexity is positive. Lens optical diameter: 6mm Refractive index at 35°C: 1.520 Thickness of outer edge of lens body: 0.18mm Posterior curvature radius: -20.0mm The results are as follows: Spherical IOL: 0.674mm Zero aberration IOL: 0.669mm Aspheric IOL: 0.626mm The IOL of the present invention: 0.632 mm In other words, the IOL based on the concept of the present invention allows for a smaller intraocular lens thickness, which makes it easier to fold the IOL and then restore it in the eye, and also reduces the wound size during surgery.

[0095] The following embodiments 1 to 4 are specific examples based on the above concept. Based on the above concept, embodiment 1 is an embodiment in which the range in which the power profile V of the intraocular lens falls is expressed as the deformation range of the aspherical reference power profile W in the first region and the deformation range of the aspherical reference power profile W in the second region. The second embodiment is an aspect in which the above concept is expressed as an increase or decrease in the value obtained by subtracting the vertical axis value of the aspherical reference power profile W from the vertical axis value of the power profiles V1 and V2. The third embodiment is a configuration in which an intermediate region is provided between the first region and the second region in the first embodiment. The fourth embodiment is an embodiment in which the power profile in the first embodiment is converted into a total power profile by adding the refractive power of the cornea. The intraocular lenses according to the following embodiments 1 to 4 are aspheric intraocular lenses. The surface of the intraocular lens that is turned (formed) into an aspheric surface to realize (create) the power profile taught by the disclosure of the present application (the present specification) may be only the front surface, only the back surface, or both the front and back surfaces (both surfaces).

[0096] [Embodiment 1] The intraocular lens according to embodiment 1 is as follows. The embodiments from embodiment 1 onwards can be arbitrarily combined with each other and each of the other embodiments (including the common embodiments). Furthermore, the content of embodiment 1 can be used in conjunction with each of the other embodiments (including the common embodiments). "A power profile Va for a first area obtained by subtracting the vertical axis value at each horizontal axis value of the aspherical reference power profile W from the base power and multiplying the result by a predetermined ratio α (α is 10% or more and 50% or less) and adding the result to the vertical axis value at each horizontal axis value of the aspherical reference power profile W; a power profile Vb for the second region obtained by adding a value obtained by subtracting the horizontal axis value at each vertical axis value of the aspherical reference power profile W from the maximum value rmax of the horizontal axis of the aspherical reference power profile W by a predetermined ratio β (β is 10% or more and 50% or less) to the horizontal axis value at each vertical axis value of the aspherical reference power profile W; The intersecting point of the power profiles Va and Vb is set as the position ra on the horizontal axis, and the intraocular lens has a power profile V that falls within the collection area of ​​the power profiles obtained by combining the power profiles Va and Vb.

[0097] The "area (hereinafter also referred to as the 'aggregate area') formed by the power profiles when the intersection of the power profile Va for the first area and the power profile Vb for the second area is at position ra on the horizontal axis" refers to the hatched portion in Figure 8. The power profile Va and the power profile Vb intersect. In the negative direction of the horizontal axis from this intersection (position ra on the horizontal axis), the power profile Va is adopted for the first area. In the positive direction of the horizontal axis from this intersection (position ra on the horizontal axis), the power profile Vb is adopted for the second area. The hatched portion in Figure 8 is the aggregate area of ​​the power profiles obtained by each combination of α being equal to or greater than 10% and equal to or less than 50%, and β being equal to or greater than 10% and equal to or less than 50%.

[0098] The maximum value rmax on the horizontal axis of the aspherical reference power profile W means the outermost edge of the lens body, that is, the optical part having a lens function.

[0099] The above content regarding "multiplying by predetermined ratios α and β" may be expressed as follows. "(Leaving the vertical axis value (base power) when the horizontal axis value is zero as it is)) The aspheric reference power profile W is reduced by a certain magnification α (α is 10% or more and 50% or less) from the negative direction of the vertical axis to the positive direction of the vertical axis, to form a power profile Va for the first area; A power profile Vb for the second region obtained by reducing the aspheric reference power profile W by a fixed magnification β (β is 10% or more and 50% or less) from the negative direction of the horizontal axis to the positive direction (leaving the horizontal axis value rmax unchanged); The intraocular lens has a power profile V that falls within the collection area of ​​the power profiles obtained by combining the power profiles Va and Vb when the intersection of the above is positioned at ra on the horizontal axis.

[0100] For example, r1 is a value within the range of 1.5 mm or more and 2.3 mm or less.

[0101] For example, at each horizontal axis value of the power profile V, the position r1 is the maximum positive value among the values ​​obtained by subtracting the vertical axis value of the aspherical reference power profile W from the vertical axis value of the power profile V. Position r1 is also the point where different power profiles are spliced ​​together.

[0102] For example, the maximum value rmax on the horizontal axis of the power profile V is a value within the range of 2.5 mm or more and 3.5 mm or less. Hereinafter, unless otherwise specified, the case where rmax is 3.0 mm will be illustrated as an example.

[0103] The intraocular lens according to this embodiment may include one or more additional regions radially extending from the second region. The additional regions surround the second region. The additional regions preferably have the function of refracting incident light onto the retina, and preferably have the function of an optical zone.

[0104] At each horizontal axis value of the power profile Vadd in at least one of the additional regions, the value obtained by subtracting the vertical axis value of the aspherical reference power profile W from the vertical axis value of the power profile Vadd may be less than ±0.30D (preferably less than ±0.15D, and the same applies hereinafter). In other words, at least one of the additional regions outside the second region (preferably the outermost additional region or the only additional region) may have a vertical axis deviation of less than ±0.30D whether it matches or does not match the aspherical reference power profile W.

[0105] As mentioned above, aspheric IOLs have good image quality when the above-mentioned changes are absent. The effect of robust image quality against the above-mentioned changes is largely achieved by the first and second regions. As a result, even if an additional region is provided outside the second region, it is preferable to adopt a power profile that closely resembles the aspheric reference power profile W as much as possible. Deviation from the plot of the aspheric reference power means the occurrence of vertical spherical aberration, which ultimately leads to a lack of vision correction. To avoid this, it is preferable to adopt a power profile that closely resembles the aspheric reference power profile W as much as possible.

[0106] The power profile V may be expressed by a polynomial. For example, the power profiles of the first region, the second region, the intermediate region described below, and the additional region can be expressed by the following polynomials: P(r) = a n r n + a n-1 r n-1 + a n-2 r n-2 + a n-3 r n-3 + . . . + a3r 3 + a2r 2 + a1r 1 + a0 ... (Formula 1) P(r): Power at the lens radius position a: coefficient r: Lens radius position n: polynomial degree

[0107] The following polynomials are polynomials in each region when the position r1 is 1.92 mm, the horizontal axis value 3.00 mm is the boundary position between the second region and the additional region (only one), and rmax is 3.25 mm (see FIG. 10). I35 I35 in the figure indicates that the predetermined percentage α in the power profile Va is 35% (for example, when α is 10%, it is written as Va(I10) as shown in Figure 2), and P O25O25 in the figure indicates that the predetermined proportion β in the power profile Vb is 25% (for example, when β is 10% as shown in FIG. 2, it is written as Vb(O10)). First area: P I35 (r)=-2.87802590e-03r 4 -4.84408818e-04r 3 -2.39306469e-01r 2 -1.30725682e-04r+20.000009 Second area: P O25 (r)=-4.38903190e-04r 4 -7.72003537e-02r 3 -3.13958521e-01r 2 +4.43293306e-01r+19.934990 Additional area: P add (r)=1.75786855r 4 -2.21096892e+01r 3 +1.03671760e+02r 2 -2.17611350e+02r+190.681131

[0108] In this embodiment, when viewed in FIG. I50 and P O50 The horizontal axis value of the intersection with rah, P O10 and P I10 The horizontal axis value of the intersection with is ral. In other words, when looking at Figure 2, in clockwise order, P I50 and, rah and, P O50 And, P O10 and,ral and,P I10 The power profile V is contained in the area surrounded by (the hatched area in Figure 8).

[0109] However, the present invention is not limited to the power profile V falling within the above region (the hatched portion in FIG. 8). For example, even if the vertical axis value of the power profile V is slightly lower than the aspheric reference power profile W when the horizontal axis value is zero or a value close to rmax, there is little effect on the optical performance of the intraocular lens (IOL), and the image quality remains robust against the above-mentioned changes. Taking this into consideration, the following embodiment 2 is a specification that strongly reflects the concept of the above invention.

[0110] [Embodiment 2] The intraocular lens according to the second embodiment is as follows. "In the first region, the average value of the vertical axis value of the power profile V1 for the first region is greater than the average value of the vertical axis value of the aspherical reference power profile W, In the second region, the average value of the vertical axis values ​​of the power profile V2 for the second region is greater than the average value of the vertical axis values ​​of the aspherical reference power profile W, In the power profile V1 for the first area, as the horizontal axis value increases, at each horizontal axis value, the value obtained by subtracting the vertical axis value of the aspheric reference power profile W from the vertical axis value of the power profile V1 increases continuously, In the power profile V2 for the second area, as the horizontal axis value increases, at each horizontal axis value, the value obtained by subtracting the vertical axis value of the aspheric reference power profile W from the vertical axis value of the power profile V2 continuously decreases, In the power profile V, the position r1 is the maximum positive value among the values ​​obtained by subtracting the vertical axis value of the aspheric reference power profile W from the vertical axis value of the power profile V2, An intraocular lens in which the value obtained by subtracting the vertical axis value of the aspheric reference power profile W from the vertical axis value at the maximum value rmax of the horizontal axis of the power profile V is less than 0.25D.

[0111] For example, the absolute value of the average value of the tangent slope of the power profile V2 in the second region is three times or more the absolute value of the average value of the tangent slope of the power profile V1 in the first region. In other words, in the power profile V of the intraocular lens according to this embodiment, power profiles having such different absolute values ​​of the average value of the tangent slope are joined together at position r1.

[0112] The meaning of "in the first region, the average value of the vertical axis values ​​of the power profile V1 for the first region is greater than the average value of the vertical axis values ​​of the aspherical reference power profile W" is as follows: It means that the average power in the first region of the intraocular lens according to this embodiment is greater than the average power of the aspherical reference power profile W in the first region. Similarly, "in the second region, the average value of the vertical axis values ​​of the power profile V2 for the second region is greater than the average value of the aspherical reference power profile W" means that the average power in the second region of the intraocular lens according to this embodiment is greater than the average power of the aspherical reference power profile W in the second region.

[0113] Note that "the subtracted value in the first region continuously increases" and "the subtracted value in the second region continuously decreases" are preferred examples and can be excluded from the regulations. Even if there is a small portion in the first region or the second region that does not satisfy these requirements, the effect of the present invention will be negligible.

[0114] Furthermore, among the above-mentioned configurations of the intraocular lens according to the second embodiment, "In the first region, the average value of the vertical axis value of the power profile V1 for the first region is greater than the average value of the vertical axis value of the aspherical reference power profile W, In the second region, the average value of the vertical axis values ​​of the power profile V2 for the second region is greater than the average value of the vertical axis values ​​of the aspherical reference power profile W. Along with the provision that "The absolute value of the average value of the tangent slope of the power profile V2 in the second region is greater than the absolute value of the average value of the tangent slope of the power profile V1 in the first region." "In the power profile V, the position r1 is the maximum positive value among the values ​​obtained by subtracting the vertical axis value of the aspheric reference power profile W from the vertical axis value of the power profile V2." "r1 is a value within the range of 1.5 mm or more and 2.3 mm or less." This rule may be adopted as the rule for the intraocular lens according to the second embodiment.

[0115] For example, r1 is a value within the range of 1.5 mm or more and 2.3 mm or less. Also, the maximum value rmax on the horizontal axis of the power profile V is a value within the range of 2.5 mm or more and 3.5 mm or less.

[0116] The following provisions adopted in the first embodiment may be applied to this embodiment. "A power profile Va for a first area obtained by subtracting the vertical axis value at each horizontal axis value of the aspherical reference power profile W from the base power and multiplying the result by a predetermined ratio α (α is 10% or more and 50% or less) and adding the result to the vertical axis value at each horizontal axis value of the aspherical reference power profile W; a power profile Vb for the second region obtained by adding a value obtained by subtracting the horizontal axis value at each vertical axis value of the aspherical reference power profile W from the maximum value rmax of the horizontal axis of the aspherical reference power profile W by a predetermined ratio β (β is 10% or more and 50% or less) to the horizontal axis value at each vertical axis value of the aspherical reference power profile W; When the intersection of the power profiles Va and Vb is positioned at ra on the horizontal axis, the power profile V is within the aggregate area of ​​the power profiles obtained by combining the power profiles Va and Vb.

[0117] One or more additional regions may be provided radially outward from the second region, the additional regions surrounding the second region, and at each horizontal axis value of the power profile Vadd in at least one of the additional regions, the value obtained by subtracting the vertical axis value of the aspheric reference power profile W from the vertical axis value of the power profile Vadd may be less than ±0.30 D. The additional region may have a function of refracting an incident light beam onto the retina.

[0118] The power profile V may be expressed by the above polynomial.

[0119] [Embodiment 3] The intraocular lens according to the third embodiment is as follows. "A power profile Va for a first area obtained by subtracting the vertical axis value at each horizontal axis value of the aspherical reference power profile W from the base power and multiplying the result by a predetermined ratio α (α is 10% or more and 50% or less) and adding the result to the vertical axis value at each horizontal axis value of the aspherical reference power profile W; a power profile Vb for the second region obtained by adding a value obtained by subtracting the horizontal axis value at each vertical axis value of the aspherical reference power profile W from the maximum value rmax of the horizontal axis of the aspherical reference power profile W by a predetermined ratio β (β is 10% or more and 50% or less) to the horizontal axis value at each vertical axis value of the aspherical reference power profile W; A power profile Vmid for an intermediate region, the average power of which is smaller than the average power in the first region and larger than the average power in the second region; An intraocular lens having a power profile V that falls within a collection area of ​​power profiles obtained by combining each of the power profiles Va, Vmid, and Vb, which is configured as follows:

[0120] In this embodiment, the intermediate region serves to connect the first region and the second region. The intermediate region may also serve as a transition region that smoothly connects the first region and the second region along the vertical axis. In other words, in this embodiment, when joining different power profiles, the power profiles are not joined directly, but rather three power profiles are joined together with another power profile sandwiched between them.

[0121] For example, the absolute value of the average value of the tangent slope of the power profile Vmid in the intermediate region is greater than the absolute value of the average value of the tangent slope of the power profile V1 in the first region, and is smaller than the absolute value of the average value of the tangent slope of the power profile V2 in the second region.

[0122] For example, at each horizontal axis value of the power profile Vmid in the intermediate region, the average value of the value obtained by subtracting the vertical axis value of the aspheric reference power profile W from the vertical axis value of the power profile Vmid is At each horizontal axis value of the power profile V1 in the first region, the horizontal axis value is greater than the average value of the value obtained by subtracting the vertical axis value of the aspherical reference power profile W from the vertical axis value of the power profile V1, and Each horizontal axis value of the power profile V2 in the second region is greater than the average value of the values ​​obtained by subtracting the vertical axis value of the aspherical reference power profile W from the vertical axis value of the power profile V2.

[0123] For example, the intermediate region is within the range of horizontal axis values ​​of 1.3 mm or more and 2.5 mm or less.

[0124] For example, the maximum value rmax on the horizontal axis of the power profile V is a value within the range of 2.5 mm or more and 3.5 mm or less.

[0125] For example, the absolute value of the average value of the tangent slope of the power profile V2 in the second region is three times or more the absolute value of the average value of the tangent slope of the power profile V1 in the first region.

[0126] For example, one or more additional regions are provided radially outward from the second region, the additional regions surround the second region, and at each horizontal axis value of the power profile Vadd in at least one of the additional regions, the value obtained by subtracting the vertical axis value of the aspheric reference power profile W from the vertical axis value of the power profile Vadd is less than ±0.30 D. The additional region has the function of refracting an incident light beam onto the retina.

[0127] For example, the power profile V is expressed as a polynomial.

[0128] The following polynomials are for each region when the boundary position between the first region and the intermediate region is 1.625 mm, the boundary position between the intermediate region and the second region is 2.485 mm, and rmax is 3.000 mm (see FIG. 12B). First area: PI35 (r)=-2.87802590e-03r 4 -4.84408818e-04r 3 -2.39306469e-01r 2 -1.30725682e-04r+20.000009 Middle area: P mid (r)=-3.75928693e-03r 4 -3.53365485e-03r 3 -3.65323646e-01r 2 +1.15 043830e-03r+20.347617 Second area: P O25 (r)=-4.38903190e-04r 4 -7.72003537e-02r 3 -3.13958521e-01r 2 +4.43293306e-01r+19.934990

[0129] [Embodiment 4] The intraocular lens according to the fourth embodiment is as follows. "In a total power profile where the horizontal axis (unit: mm) represents the position when viewed in the radial direction from the lens center O, and the vertical axis (unit: D (diopter)) represents the total power T when the refractive power of the cornea and the power of the intraocular lens are added together, when the position of the first boundary between the first and second regions when viewed in the radial direction from the lens center O is set to r1, a total power profile TVa for the first region obtained by subtracting the vertical axis value at each horizontal axis value of the aspherical reference total power profile TW, to which the refractive power of the cornea has been added, from the base power, and multiplying the result by a predetermined ratio α (α is 10% or more and 50% or less), and adding the result to the vertical axis value at each horizontal axis value of the aspherical reference total power profile TW; a total power profile TVb for the second region obtained by subtracting the horizontal axis value at each vertical axis value of the aspherical reference total power profile TW, to which the refractive power of the cornea has been added, from the maximum value rmax of the horizontal axis of the aspherical reference total power profile TW, and multiplying the result by a predetermined ratio β (β is 10% or more and 50% or less), and adding the obtained value to the horizontal axis value at each vertical axis value of the aspherical reference total power profile TW; The intraocular lens has a total power profile TV that falls within the aggregate area of ​​the total power profiles obtained by combining the total power profiles TVa and TVb when the intersection of the above is positioned at ra on the horizontal axis.

[0130] In the total power profile TV1 for the first region, the vertical axis value increases continuously as the horizontal axis value increases, In the total power profile TV2 for the second region, the vertical axis values ​​may continuously decrease as the horizontal axis values ​​increase.

[0131] The absolute value of the average value of the slope of the tangent of the total power profile TV1 near the origin in the first region is smaller than the absolute value of the average value of the slope of the tangent of the total power profile TV1 near the intermediate position in the first region; the absolute value of the average value of the slope of the tangent of the total power profile TV1 in the vicinity of the intermediate position in the first region is greater than the absolute value of the average value of the slope of the tangent of the total power profile TV1 in the vicinity of the position r1 in the first region; The absolute value of the average value of the tangent slope of the total power profile TV1 near the position r1 in the first region may be smaller than the absolute value of the average value of the tangent slope of the total power profile TV2 near the intermediate position in the second region. Here, "vicinity" refers to, for example, within ±0.20 mm (or 0.10 mm) of the intermediate position.

[0132] For example, in the total frequency profile TV, the value obtained by subtracting the vertical axis value at r=0 from the vertical axis value at position r1 is the maximum positive value, The value of r1 is within the range of 1.5 mm or more and 2.3 mm or less.

[0133] For example, the value obtained by subtracting the vertical axis value at r=0 from the vertical axis value at the maximum value rmax of the horizontal axis of the total power profile TV is less than ±0.30D.

[0134] For example, the maximum value rmax on the horizontal axis of the total power profile TV is a value within the range of 2.5 mm or more and 3.5 mm or less.

[0135] For example, one or more additional regions are provided radially outward from the second region, the additional regions surround the second region, and the additional regions have the function of refracting incident light beams onto the retina.

[0136] [others] The intraocular lens of this embodiment is not limited to the above-described embodiment, but also includes forms with various modifications and improvements made within the scope that can derive specific effects obtained by the constituent elements of the invention and their combinations.

[0137] The area ratio between the first region and the second region in a plan view may be set to a value between 25:75 and 75:25.

[0138] In the first region, the power preferably decreases continuously. In the second region, the power preferably decreases continuously.

[0139] Between the lens center O and the position r1 of the first boundary, it is preferable that the total power T obtained by adding the refractive power of the cornea and the power of the intraocular lens increases continuously.

[0140] Instead of directly patching together different power profiles, a profile that mimics the patchwork may be used. The polynomial that describes such a power profile is as follows: P Np (r) = -8.31778546e-02r 8 + 9.97022762e-01r 7 - 4.79532863e+00r 6 + 1.18428403e+01r 5- 1.60518818e+01r 4 + 1.18152492e+01r 3 - 4.57931927e+00r 2 + 6.59257903e-01r + 19.976408

[0141] Although an intraocular lens has been exemplified in each embodiment, the technical idea (concept) of the present invention can also be applied to a design method for an intraocular lens, and to a manufacturing method for an intraocular lens in which an intraocular lens designed by the design method for an intraocular lens is manufactured by at least one of lathe turning, molding, and 3D printing.

[0142] [Specific example] The intraocular lens of this embodiment is not limited to the above-described embodiment, but also includes forms with various modifications and improvements made within the scope that can derive specific effects obtained by the constituent elements of the invention and their combinations.

[0143] A specific example of the power profile will be described below. In the following example, the parameters of the above condition 1 are used.

[0144] FIG. 2 is a power profile showing the refractive power (vertical axis) provided by the optical portion of an intraocular lens versus the distance from the lens center O (horizontal axis) in an embodiment of the present invention. In Figure 2, the power profile of a spherical IOL is shown by a dotted line, the power profile of a zero-aberration IOL by a dashed line, the power profile of an aspherical IOL (aspherical reference power profile W) by a dashed-dotted line, and the IOL of the concept of the present invention by a solid line. I50 And, P O50 And, P O10 And, P I10 The power profile V is contained in the area surrounded by and (hatched area).

[0145] Figure 3 is a power profile showing the refractive power (vertical axis) provided by the optical part of the intraocular lens versus the distance from the lens center O (horizontal axis), and is a diagram showing the power profile Va obtained by multiplying the value obtained by subtracting the vertical axis value at each horizontal axis value of the aspherical reference power profile W from the base power by a predetermined percentage α (α is a value between 10% and 50%, and is 10%, i.e., I10, 35%, i.e., I35, and 50%, i.e., I50).

[0146] Figure 4 is a power profile showing the refractive power (vertical axis) provided by the optical part of the intraocular lens versus the distance from the lens center O (horizontal axis), and is a diagram showing a power profile Vb obtained by adding the value obtained by subtracting the horizontal axis value at each vertical axis value of the aspherical reference power profile W from the maximum value rmax of the horizontal axis of the aspherical reference power profile W by a predetermined ratio β (β is a value between 10% and 50%, where 10% is O10, 25% is O25, and 50% is O50) to the horizontal axis value at each vertical axis value of the aspherical reference power profile W.

[0147] FIG. 5 is an explanatory diagram of I35 in FIG. 3 and O25 in FIG. 4 superimposed on each other. FIG. 6 is a diagram showing a power profile V obtained by joining together the power profile Va (I35) for the first region and the power profile Vb (O25) for the second region in FIG. Hereafter, this power profile V will be referred to as "I35-O25." Power profile V will be described in the same format from now on. The aspherical reference power profile W is shown as a dotted line in both Fig. 5 and Fig. 6. The aspherical reference power profile W is also shown in the subsequent figures as appropriate. FIG. 7 is a diagram showing I10-O10, I40-O20, and I50-O50. In FIG. 7, the aspheric reference power profile W is shown as a solid line.

[0148] Figure 8 shows the area (hatched portion) composed of the power profile when the intersection of the power profile Va for the first area (α is 10% or more and 50% or less) and the power profile Vb for the second area (β is 10% or more and 50% or less) is set at position ra on the horizontal axis.

[0149] 9 is a diagram showing a power profile V (solid line) in an [other] embodiment of the present invention, in which different power profiles are not directly patched together, but a profile that imitates the patched-up power profile is used. The aspheric reference power profiles W (dotted line), I10-O10 (dashed line), and I50-O50 (chain-dotted line) are also shown.

[0150] FIG. 10 is a diagram showing a power profile V (solid line, I35-O25, optical zone diameter 6.50 mm) when an additional region is provided.

[0151] The following specific examples mainly relate to the second embodiment.

[0152] Figure 11 is a diagram showing I10-O10 and I50-O50, and also shows, for each power profile V, the average value of the tangent slope of the power profile V1 in the first region and the absolute value of the average value of the tangent slope of the power profile V2 in the second region. In Figure 11, I10-O10 and I50-O50 are In the power profile V1 for the first area, as the horizontal axis value increases, at each horizontal axis value, the value obtained by subtracting the vertical axis value of the aspheric reference power profile W from the vertical axis value of the power profile V1 increases continuously, In the power profile V2 for the second area, as the horizontal axis value increases, at each horizontal axis value, the value obtained by subtracting the vertical axis value of the aspheric reference power profile W from the vertical axis value of the power profile V2 continuously decreases, In the power profile V, the position r1 is the maximum positive value among the values ​​obtained by subtracting the vertical axis value of the aspheric reference power profile W from the vertical axis value of the power profile V2, The value obtained by subtracting the vertical axis value of the aspherical reference power profile W from the vertical axis value at the maximum value rmax of the horizontal axis of the power profile V is less than 0.25D. Also, The absolute value of the average value of the tangent slope of the power profile V2 in the second region is three times or more the absolute value of the average value of the tangent slope of the power profile V1 in the first region. At each horizontal axis value of the power profile Vadd in the additional region, the value obtained by subtracting the vertical axis value of the aspherical reference power profile W from the vertical axis value of the power profile Vadd is less than ±0.30D.

[0153] The numerical range of the absolute value of the average value of the slope of the tangent to the power profile V1 in the first region may have an upper limit of 0.73 D / mm and a lower limit of 0.46 D / mm, for example. The numerical range of the absolute value of the average value of the slope of the tangent to the power profile V2 in the second region may be, for example, 3.94 D / mm as the upper limit and 2.36 D / mm as the lower limit.

[0154] The following specific examples mainly relate to the third embodiment. FIG. 12A is a diagram showing a power profile V (solid line, I35-O25) when an intermediate region is provided. FIG. 12B is a diagram showing the intermediate region of FIG. 12A expanded. FIG. 12C is a diagram showing a power profile V (solid line, I40-O40) when an intermediate region is provided.

[0155] The following specific examples mainly relate to the fourth embodiment. FIG. 13 is a table showing conditions employed in the total power profile according to the embodiment of the present invention. FIG. 14 is a total power profile TV showing the total power T (vertical axis) when the refractive power of the cornea and the power of the intraocular lens are combined, versus the distance from the lens center O (horizontal axis).

[0156] The total power profile of Figure 14 is designed in this example by using the well-known optical design software ZEMAX (registered trademark) (manufactured by ZEMAX Development Corporation, USA) to model the optical system of the cornea and IOL and design the aspheric anterior surface of the IOL.

[0157] 14, the power profile of a spherical IOL is shown by a dotted line, the power profile of a zero-aberration IOL by a dashed line, and the IOL based on the concept of the present invention by a solid line. Regarding the total power profile of an aspheric IOL, the total power profile when the spherical aberration value of the corneal model (shown as a negative value in each figure) is 0.07 μm is shown by a wide dotted line, the total power profile when it is 0.20 μm is shown by a narrow dotted line, and the total power profile when it is 0.27 μm is shown by a dashed-dotted line. FIG. 15 is a diagram showing the total power profile TV when the horizontal axis value rmax of 3.0 mm is matched with the vertical axis value when the horizontal axis value is zero.

[0158] Figure 16 shows the area (hatched portion) composed of the total power profile when the intersection of the total power profile TVa for the first area (α is 10% or more and 50% or less) and the total power profile TVb for the second area (β is 10% or more and 50% or less) is set at position ra on the horizontal axis.

[0159] The following examples demonstrate that the present invention provides robust image quality against changes in displacement, tilt, and pupil diameter while maintaining good image quality. At least one of I40-O40 and I35-O25 in the following examples demonstrates robust image quality against changes in displacement, tilt, and pupil diameter even when the above-mentioned changes are present, while exhibiting MTF values ​​comparable to those of aspherical IOLs. This robustness is comparable to that of spherical IOLs or zero-aberration IOLs. In other words, the present invention allows users to combine the best features of spherical IOLs, zero-aberration IOLs, and aspherical IOLs.

[0160] Before that, we will explain the MTF values ​​for a spherical IOL (dotted line), a zero-aberration IOL (dashed line), an aspherical IOL (narrow dotted line), and an IOL based on the concept of the present invention (I40-O40 is shown as a solid line, and I35-O25 is shown as a dashed-dotted line) when the above changes are not present. This explanation will be the same for the following figures.

[0161] FIG. 17 is a plot showing the MTF value (vertical axis) indicating contrast against the object distance (horizontal axis) from the corneal apex (aperture diameter (pupil diameter) set to 3.0 to 4.5 mm, and no displacement or tilt).

[0162] The plots are obtained by the ZEMAX method. The specific details of the test can be found in WO2008 / 078804 filed by the applicant of the present invention.

[0163] The MTF (Modulation Transfer Function) value is one of the measures used to evaluate lens performance, and it represents the degree to which the contrast of an object viewed can be faithfully reproduced on the image plane as a spatial frequency characteristic. A high MTF value means that the wearer perceives a high contrast when viewing an object through the lens.

[0164] Figure 18 is a plot showing the MTF value (vertical axis) indicating contrast against the object distance (horizontal axis) from the corneal apex (aperture diameter (pupil diameter) set to 3.0 to 4.5 mm, displacement 0.3 mm, no tilt).

[0165] Figure 19 is a plot showing the MTF value (vertical axis) indicating contrast against the object distance (horizontal axis) from the corneal apex (aperture diameter (pupil diameter) set to 3.0 to 4.5 mm, displacement 0.5 mm, no tilt).

[0166] Figure 20 is a plot showing the MTF value (vertical axis) indicating contrast against the object distance (horizontal axis) from the corneal apex (aperture diameter (pupil diameter) set to 3.0 to 4.5 mm, no displacement, tilt of 3 degrees).

[0167] Figure 21 is a plot showing the MTF value (vertical axis) indicating contrast against the object distance (horizontal axis) from the corneal apex (aperture diameter (pupil diameter) set to 3.0 to 4.5 mm, no displacement, inclination of 5 degrees).

[0168] Figure 22 is a plot showing the MTF value (vertical axis) indicating contrast against the object distance (horizontal axis) from the corneal apex (aperture diameter (pupil diameter) set to 3.0 to 4.5 mm, displacement 0.3 mm, tilt 3 degrees).

[0169] Figure 23 is a plot showing the MTF value (vertical axis) indicating contrast against the object distance (horizontal axis) from the corneal apex (aperture diameter (pupil diameter) set to 3.0 to 4.5 mm, displacement 0.4 mm, tilt 4 degrees).

[0170] Figure 24 is a plot showing the MTF value (vertical axis) indicating contrast against the object distance (horizontal axis) from the corneal apex (aperture diameter (pupil diameter) set to 3.0 to 4.5 mm, displacement 0.5 mm, inclination 5 degrees).

[0171] FIG. 25 is a plot showing the MTF value (vertical axis) indicating contrast against the displacement (horizontal axis) (object distance set to 2.0 m, aperture diameter (pupil diameter) set to 3.0 mm and 4.0 mm, inclination 0 to 5 degrees).

[0172] FIG. 26 is a plot showing the MTF value (vertical axis) indicating contrast against the displacement (horizontal axis) (object distance set to 3.0 m, aperture diameter (pupil diameter) set to 3.0 mm and 4.0 mm, inclination 0 to 5 degrees).

[0173] FIG. 27 is a plot showing the MTF value (vertical axis) indicating contrast against the displacement (horizontal axis) (object distance set to 4.0 m, aperture diameter (pupil diameter) set to 3.0 mm and 4.0 mm, inclination 0 to 5 degrees).

[0174] FIG. 28 is a plot showing the MTF value (vertical axis) indicating contrast against the tilt (horizontal axis) (object distance set to 2.0 m, aperture diameter (pupil diameter) set to 3.0 mm and 4.0 mm, and displacement from 0 to 0.5 mm).

[0175] FIG. 29 is a plot showing the MTF value (vertical axis) indicating contrast against the tilt (horizontal axis) (object distance set to 3.0 m, aperture diameter (pupil diameter) set to 3.0 mm and 4.0 mm, and displacement 0 to 0.5 mm).

[0176] FIG. 30 is a plot showing the MTF value (vertical axis) indicating contrast against the tilt (horizontal axis) (object distance set to 4.0 m, aperture diameter (pupil diameter) set to 3.0 mm and 4.0 mm, and displacement 0 to 0.5 mm).

[0177] [Embodiment 5] This embodiment is also applicable to an intraocular lens in which a positive power is added to at least a portion of the power profile in the first region to correct the near vision and / or intermediate vision of an aphakic patient.

[0178] The technical concept of the fifth embodiment can also be applied to monofocal lenses. For example, an added positive power (e.g., one or more positive fixed powers) of 0.75D to 1.75D can be used, such as an enhanced monofocal IOL (commonly known as an EM-IOL). The technical concept of the fifth embodiment can also be applied to multifocal lenses (e.g., an added positive power, i.e., an add power, of 2.5D to 4.0D), as well as extended depth-of-focus IOLs (commonly known as EDOFs), which are intermediate lenses between multifocal lenses and EM-IOLs (e.g., an added positive power greater than 1.75D and less than 2.5D).

[0179] The region to which positive power is added is called the Inner First Region. The region located outside of the Inner First Region (located in the direction away from the lens center O) and having the same power profile Va as the first region described above is called the Outer First Region. An example of this will be described below as embodiment 5 using Figures 31 to 34.

[0180] The intraocular lens according to the fifth embodiment is as follows. "An intraocular lens having at least two areas for vision correction that are concentric and adjacent to each other with a lens center O set with a predetermined base power, The vision correction area is set in order from a first area including the lens center O toward the radially outward side, and a second area surrounding the first area is set; In the power profile, the horizontal axis (unit: mm) represents the position when viewed radially from the lens center O, and the vertical axis represents the power (unit: D (diopter)). The power profile of a hypothetical aspheric lens that has a base power at the lens center O and completely offsets the positive vertical spherical aberration caused by the cornea is defined as an aspheric reference power profile W, a power profile obtained by adding a value obtained by subtracting the vertical axis value at each horizontal axis value of the aspherical reference power profile W from the base power and multiplying the result by a predetermined ratio α (α is 10% or more and 50% or less) to the vertical axis value at each horizontal axis value of the aspherical reference power profile W is defined as a power profile Va for the first region; When a power profile Vb for the second region is a power profile obtained by adding a value obtained by subtracting the horizontal axis value at each vertical axis value of the aspherical reference power profile W from the maximum value rmax of the horizontal axis of the aspherical reference power profile W by a predetermined ratio β (β is 10% or more and 50% or less) to the horizontal axis value at each vertical axis value of the aspherical reference power profile W, The first region includes an inner first region having a power profile in which a positive power is added to a power profile Va for the first region, the second region has a power profile Vb; An intraocular lens, wherein the area of ​​the inner first region is less than 50% of the total area of ​​the first regions."

[0181] For ease of explanation, the case where the lens center O is included in the inner first region will be referred to as embodiment 5A, and the case where this is not the case (the case where the lens center O is included in the innermost region described below, which has the same power profile as the power profile Va) will be referred to as embodiment 5B.

[0182] That is, in embodiment 5A, the inner first region may include the lens center O, as shown in FIGS. 31A to 33A and 34. Also, in embodiment 5B, as shown in Figures 31B to 33B, the first region may include an innermost region having the same power profile Va as that for the outer first region and including the lens center O, and the inner first region may surround the innermost region.

[0183] The symbols A and B in Figures 31 to 34 correspond to the embodiments 5A and 5B. Figure 34 belongs to embodiment 5A. Both embodiments are referred to as embodiment 5.

[0184] As in the above embodiments, the first region contacts the second region at the intersection point ra between the power profiles Va and Vb. As a specific example, the outer first region in the first region contacts the second region at the intersection point ra.

[0185] To correct near and / or intermediate vision in aphakic patients, the spectacle lenses may comprise an inner first zone, comprised of one or more zones, in the interior region of the optic of the IOL of the present invention, as shown in Figures 31A, 31B, 32A, and 32B, where the area of ​​the inner first zone is less than 50% of the area of ​​the first zone.

[0186] The inner first region may include a constant power addition region having a power profile in which a constant positive power is added to the power profile Va for the outer first region.

[0187] "Power with a fixed positive power added to the power profile Va" means that at a specified distance from the lens center O, the deviation from the plot with a fixed positive power added to the power profile Va is less than ±0.30D (preferably less than ±0.15D).

[0188] The power added may be something other than a positive constant power. There may be a portion where a positive constant power is added and a portion where a non-positive power is added, and Figure 32A shows an example. Specifically, in the portion of the power profile from 0 mm to approximately 0.30 mm on the horizontal axis, which is the lens center O, a non-constant positive power is added. Moreover, this added power is greater than the positive constant power; in other words, it brings about a positive power deviation from the positive constant power. This portion is called the positive power deviation region. A positive constant power is added from approximately 0.30 mm to 0.80 mm. This portion is called the constant power addition region.

[0189] The positive power deviation region may be a power profile that is convex upward as shown in Figures 32A, 33A, and 34, or conversely, may be a power profile that is convex downward. It is preferable that the average value of the absolute values ​​of the differences between the power profile of the positive power deviation region and a power profile in which a fixed positive power is added to the power profile Va is large. In other words, it is preferable that the positive power deviation region be a power profile that is convex upward.

[0190] The shapes of the power profiles in the regions constituting the inner first region may be different from each other. The shapes may be continuous, discontinuous (step-like), or a combination of different shapes. Figures 32A and 32B show a case where different power profiles, a positive power deviation region and a fixed power addition region, are adjacently combined.

[0191] When viewed radially from the lens center O, the radial distance of the fixed power added region may be 33 to 67% of the radial distance of the inner first region (FIG. 34). When the first region includes a region other than the inner first region whose average power is equal to that of the power profile Va, the average power of the inner first region may be 0.75 to 4.0 D greater than that of the region other than the inner first region. This configuration enables aphakic patients to receive clear images of objects at specific near or intermediate distances. Examples of regions whose average power is equal to that of the power profile Va include the outer first region and / or the innermost region. In the case of this paragraph, even if the outer first region and / or the innermost region do not completely match the power profile Va, the average power may satisfy the above relationship. Furthermore, the "region other than the inner first region" may exclude not only the inner first region but also the transition region described below. In accordance with this definition, the average power of the inner first region may be 0.75 to 4.0 D greater than the average power of the region other than the inner first region.

[0192] The intraocular lens may have two opposing surfaces and the lens body may have an inner first region on the anterior surface, the posterior surface, or both.

[0193] As shown in Figure 33A, in embodiment 5A, the first region may include an outer transition region for smoothly connecting the inner first region to the outer first region. In addition, as shown in Figure 33B, in embodiment 5B, the first region may include an inner transition region for smoothly connecting the inner first region to the innermost region. Both transition regions cause a decrease in power toward the power profile Va, in other words, a negative power deviation from the above-mentioned positive constant power.

[0194] Each transition region may have a power profile that is convex downward as shown in Figures 33A and 33B, or conversely, may have a power profile that is convex upward. It is preferable that the average value of the absolute values ​​of the differences between the power profile of the positive power deviation region and the power profile in which a positive fixed power is added to the power profile Va is small. In other words, it is preferable that the positive power deviation region has a power profile that is convex downward.

[0195] The present invention also allows for the case where the outer first region is not provided. That is, an inner first region (e.g., a fixed power addition region) or an outer transition region may be provided so as to contact the intersection point ra of the power profiles Va and Vb. In this case, the average power in the first region is increased, thereby enhancing near and intermediate vision.

[0196] The anterior surface, posterior surface, or both of the lens body of an intraocular lens having two opposing surfaces may be aspheric.

[0197] The front surface, the back surface, or both of the lens body of an intraocular lens having two opposing surfaces may have a toric surface with a cylindrical power for correcting astigmatism in an aphakic patient.

Claims

1. An intraocular lens having at least two areas for vision correction that are concentric and adjacent to each other with a lens center O having a predetermined base power set thereto, The vision correction area is set in order from a first area including the lens center O toward the radially outer side, and a second area surrounding the first area is set, In a power profile in which the horizontal axis represents the position (unit: mm) when viewed in the radial direction from the lens center O, and the vertical axis represents the power (unit: D (diopter)), when the position of the first boundary between the first region and the second region when viewed in the radial direction from the lens center O is set to r1, and When the power profile of a hypothetical aspherical lens that has a base power at the lens center O and completely offsets the positive vertical spherical aberration caused by the cornea is defined as an aspherical reference power profile W, a power profile Va for the first region obtained by adding a value obtained by subtracting the vertical axis value at each horizontal axis value of the aspherical reference power profile W from the base power and multiplying the result by a predetermined ratio α (α is 10% or more and 50% or less) to the vertical axis value at each horizontal axis value of the aspherical reference power profile W; a power profile Vb for the second region obtained by adding a value obtained by subtracting the horizontal axis value at each vertical axis value of the aspherical reference power profile W from the maximum value rmax of the horizontal axis of the aspherical reference power profile W by a predetermined ratio β (β is 10% or more and 50% or less) to the horizontal axis value at each vertical axis value of the aspherical reference power profile W; The intraocular lens has a power profile V that falls within a collection area of ​​power profiles obtained by combining the power profiles Va and Vb when the intersection of the power profiles Va and Vb is positioned at the horizontal axis as ra.

2. The intraocular lens according to claim 1, wherein r1 is a value within the range of 1.5 mm or more and 2.3 mm or less.

3. The intraocular lens of claim 1, wherein, at each horizontal axis value of the power profile V, the maximum positive value among the values ​​obtained by subtracting the vertical axis value of the aspherical reference power profile W from the vertical axis value of the power profile V is at position r1.

4. The intraocular lens according to claim 1, wherein the maximum value rmax on the horizontal axis of the power profile V is within a range of 2.5 mm or more and 3.5 mm or less.

5. one or more additional regions radially outward from the second region; the additional region surrounds the second region; The intraocular lens of claim 1, wherein at each horizontal axis value of the power profile Vadd in at least one of the additional regions, the value obtained by subtracting the vertical axis value of the aspheric reference power profile W from the vertical axis value of the power profile Vadd is less than ±0.30D.

6. The intraocular lens according to claim 1 , wherein the power profile V is expressed by a polynomial.

7. one or more additional regions radially outward from the second region; the additional region surrounds the second region; The intraocular lens according to claim 1 , wherein the additional region has a function of refracting incident light beams onto the retina.

8. An intraocular lens having at least two areas for vision correction that are concentric and adjacent to each other with a lens center O having a predetermined base power set thereto, The vision correction area is set in order from a first area including the lens center O toward the radially outer side, and a second area surrounding the first area is set, In a power profile in which the horizontal axis represents the position (unit: mm) when viewed in the radial direction from the lens center O, and the vertical axis represents the power (unit: D (diopter)), when the position of the first boundary between the first region and the second region when viewed in the radial direction from the lens center O is set to r1, and When the power profile of a hypothetical aspherical lens that has a base power at the lens center O and completely offsets the positive vertical spherical aberration caused by the cornea is defined as an aspherical reference power profile W, In the first region, the average value of the vertical axis values ​​of the power profile V1 for the first region is greater than the average value of the vertical axis values ​​of the aspherical reference power profile W, In the second region, the average value of the vertical axis values ​​of the power profile V2 for the second region is greater than the average value of the vertical axis values ​​of the aspherical reference power profile W, In the power profile V1 for the first region, as the horizontal axis value increases, at each horizontal axis value, the value obtained by subtracting the vertical axis value of the aspherical reference power profile W from the vertical axis value of the power profile V1 continuously increases, In the power profile V2 for the second region, as the horizontal axis value increases, the value obtained by subtracting the vertical axis value of the aspherical reference power profile W from the vertical axis value of the power profile V2 at each horizontal axis value continuously decreases, In the power profile V, the position r1 is the maximum positive value among the values ​​obtained by subtracting the vertical axis value of the aspherical reference power profile W from the vertical axis value of the power profile V2, An intraocular lens in which the value obtained by subtracting the vertical axis value of the aspheric reference power profile W from the vertical axis value at the maximum value rmax on the horizontal axis of the power profile V is less than 0.25D.

9. The intraocular lens of claim 8, wherein the absolute value of the average value of the tangent slope of the power profile V2 in the second region is three times or more the absolute value of the average value of the tangent slope of the power profile V1 in the first region.

10. The intraocular lens according to claim 8, wherein r1 is a value within the range of 1.5 mm or more and 2.3 mm or less.

11. The intraocular lens according to claim 8, wherein the maximum value rmax on the horizontal axis of the power profile V is a value within the range of 2.5 mm or more and 3.5 mm or less.

12. a power profile Va for the first region obtained by adding a value obtained by subtracting the vertical axis value at each horizontal axis value of the aspherical reference power profile W from the base power and multiplying the result by a predetermined ratio α (α is 10% or more and 50% or less) to the vertical axis value at each horizontal axis value of the aspherical reference power profile W; a power profile Vb for the second region obtained by adding a value obtained by subtracting the horizontal axis value at each vertical axis value of the aspherical reference power profile W from the maximum value rmax of the horizontal axis of the aspherical reference power profile W by a predetermined ratio β (β is 10% or more and 50% or less) to the horizontal axis value at each vertical axis value of the aspherical reference power profile W; The intraocular lens according to claim 8, wherein the intraocular lens has a power profile V that falls within a collection area of ​​power profiles obtained by combining the power profiles Va and Vb when the intersection point of the power profiles Va and Vb is positioned at ra on the horizontal axis.

13. one or more additional regions radially outward from the second region; the additional region surrounds the second region; The intraocular lens of claim 8, wherein at each horizontal axis value of the power profile Vadd in at least one of the additional regions, the value obtained by subtracting the vertical axis value of the aspheric reference power profile W from the vertical axis value of the power profile Vadd is less than ±0.30D.

14. The intraocular lens according to claim 8 , wherein the power profile V is expressed by a polynomial.

15. one or more additional regions radially outward from the second region; the additional region surrounds the second region; The intraocular lens according to claim 8 , wherein the additional region has a function of refracting incident light beams onto the retina.

16. An intraocular lens having at least two areas for vision correction that are concentric and adjacent to each other with a lens center O having a predetermined base power set thereto, The vision correction regions are set in the order from a first region including the lens center O toward the outside in the radial direction, to an intermediate region surrounding the first region and a second region surrounding the intermediate region, In a power profile where the horizontal axis represents the position (unit: mm) when viewed in the radial direction from the lens center O and the vertical axis represents the power (unit: D (diopter)), When the power profile of a hypothetical aspherical lens that has a base power at the lens center O and completely offsets the positive vertical spherical aberration caused by the cornea is defined as an aspherical reference power profile W, a power profile Va for the first region obtained by adding a value obtained by subtracting the vertical axis value at each horizontal axis value of the aspherical reference power profile W from the base power and multiplying the result by a predetermined ratio α (α is 10% or more and 50% or less) to the vertical axis value at each horizontal axis value of the aspherical reference power profile W; a power profile Vb for the second region obtained by adding a value obtained by subtracting the horizontal axis value at each vertical axis value of the aspherical reference power profile W from the maximum value rmax of the horizontal axis of the aspherical reference power profile W by a predetermined ratio β (β is 10% or more and 50% or less) to the horizontal axis value at each vertical axis value of the aspherical reference power profile W; a power profile Vmid for an intermediate region, the average power of which is smaller than the average power in the first region and larger than the average power in the second region; An intraocular lens having a power profile V that falls within a collection area of ​​power profiles obtained by combining each of the power profiles Va, Vmid, and Vb.

17. 17. The intraocular lens of claim 16, wherein the absolute value of the average value of the tangent slope of the power profile Vmid in the intermediate region is greater than the absolute value of the average value of the tangent slope of the power profile V1 in the first region and less than the absolute value of the average value of the tangent slope of the power profile V2 in the second region.

18. At each horizontal axis value of the power profile Vmid in the intermediate region, the average value of the values ​​obtained by subtracting the vertical axis value of the aspheric reference power profile W from the vertical axis value of the power profile Vmid is At each horizontal axis value of the power profile V1 in the first region, it is greater than the average value of the value obtained by subtracting the vertical axis value of the aspherical reference power profile W from the vertical axis value of the power profile V1, and The intraocular lens of claim 16, wherein each horizontal axis value of the power profile V2 in the second region is greater than the average value of the vertical axis value of the power profile V2 minus the vertical axis value of the aspheric reference power profile W.

19. The intraocular lens according to claim 16, wherein the intermediate region has a horizontal axis value within a range of 1.3 mm or more and 2.5 mm or less.

20. The intraocular lens according to claim 16, wherein the maximum value rmax of the horizontal axis of the power profile V is within the range of 2.5 mm or more and 3.5 mm or less.

21. 17. The intraocular lens of claim 16, wherein the absolute value of the average value of the tangent slope of the power profile V2 in the second region is three times or more the absolute value of the average value of the tangent slope of the power profile V1 in the first region.

22. one or more additional regions radially outward from the second region; the additional region surrounds the second region; 17. The intraocular lens of claim 16, wherein at each horizontal axis value of the power profile Vadd in at least one of the additional regions, the value obtained by subtracting the vertical axis value of the aspheric reference power profile W from the vertical axis value of the power profile Vadd is less than ±0.30D.

23. The intraocular lens of claim 16, wherein the power profile V is expressed by a polynomial.

24. one or more additional regions radially outward from the second region; the additional region surrounds the second region; The intraocular lens according to claim 16, wherein the additional region has a function of refracting incident light beams onto the retina.

25. An intraocular lens having at least two areas for vision correction that are concentric and adjacent to each other with a lens center O having a predetermined base power set thereto, The vision correction area is set in order from a first area including the lens center O toward the radially outer side, and a second area surrounding the first area is set, When the power profile of a hypothetical aspherical lens that has a base power at the lens center O and completely offsets the positive vertical spherical aberration caused by the cornea is defined as an aspherical reference power profile W, In a total power profile in which the horizontal axis represents the position when viewed in the radial direction from the lens center O (unit: mm) and the vertical axis represents the total power T when the refractive power of the cornea and the power of the intraocular lens are added together (unit: D (diopter)), when the position of the first boundary between the first region and the second region when viewed in the radial direction from the lens center O is set to r1, a total power profile TVa for the first region obtained by subtracting the vertical axis value at each horizontal axis value of the aspherical reference total power profile TW, to which the refractive power of the cornea has been added, from the base power, and multiplying the result by a predetermined ratio α (α is 10% or more and 50% or less), and adding the result to the vertical axis value at each horizontal axis value of the aspherical reference total power profile TW; a total power profile TVb for the second region obtained by subtracting the horizontal axis value at each vertical axis value of the aspherical reference total power profile TW, to which the refractive power of the cornea has been added, from the maximum value rmax of the horizontal axis of the aspherical reference total power profile TW, and multiplying the result by a predetermined ratio β (β is 10% or more and 50% or less), and adding the obtained value to the horizontal axis value at each vertical axis value of the aspherical reference total power profile TW; An intraocular lens having a total power profile TV that falls within a collection area of ​​total power profiles obtained by combining each of the total power profiles TVa and TVb when the intersection of the above is positioned at position ra on the horizontal axis.

26. In the total power profile TV1 for the first region, the vertical axis value increases continuously as the horizontal axis value increases, The intraocular lens according to claim 25, wherein in the total power profile TV2 for the second region, the vertical axis values ​​continuously decrease as the horizontal axis values ​​increase.

27. the absolute value of the average value of the slope of the tangent to the total power profile TV1 near the origin in the first region is smaller than the absolute value of the average value of the slope of the tangent to the total power profile TV1 near the intermediate position in the first region; the absolute value of the average value of the slope of the tangent to the total power profile TV1 in the vicinity of the intermediate position in the first region is greater than the absolute value of the average value of the slope of the tangent to the total power profile TV1 in the vicinity of the position r1 in the first region; An intraocular lens as described in claim 25, wherein the absolute value of the average value of the tangent slope of the total power profile TV1 near position r1 in the first region is smaller than the absolute value of the average value of the tangent slope of the total power profile TV2 near the intermediate position in the second region.

28. In the total power profile TV, the value obtained by subtracting the vertical axis value at r=0 from the vertical axis value at position r1 is the maximum positive value, 26. The intraocular lens of claim 25, wherein r1 is a value in the range of 1.5 mm or more and 2.3 mm or less.

29. The intraocular lens according to claim 25, wherein the value obtained by subtracting the vertical axis value at r=0 from the vertical axis value at the maximum value rmax of the horizontal axis of the total power profile TV is less than ±0.30D.

30. The intraocular lens according to claim 25, wherein the maximum value rmax on the horizontal axis of the total power profile TV is within the range of 2.5 mm or more and 3.5 mm or less.

31. one or more additional regions radially outward from the second region; the additional region surrounds the second region; 26. The intraocular lens according to claim 25, wherein the additional region has the function of refracting incident light beams onto the retina.

32. An intraocular lens having at least two areas for vision correction that are concentric and adjacent to each other with a lens center O having a predetermined base power set thereto, The vision correction area is set in order from a first area including the lens center O toward the radially outer side, and a second area surrounding the first area is set, In a power profile where the horizontal axis represents the position (unit: mm) when viewed in the radial direction from the lens center O and the vertical axis represents the power (unit: D (diopter)), The power profile of a hypothetical aspherical lens that has a base power at the lens center O and completely offsets the positive vertical spherical aberration caused by the cornea is defined as an aspherical reference power profile W, a power profile obtained by adding a value obtained by subtracting the vertical axis value at each horizontal axis value of the aspherical reference power profile W from the base power and multiplying the result by a predetermined ratio α (α is 10% or more and 50% or less) to the vertical axis value at each horizontal axis value of the aspherical reference power profile W is defined as a power profile Va for the first region; When a power profile Vb for the second region is a power profile obtained by adding a value obtained by subtracting the horizontal axis value at each vertical axis value of the aspherical reference power profile W from the maximum value rmax of the horizontal axis of the aspherical reference power profile W by a predetermined ratio β (β is 10% or more and 50% or less) to the horizontal axis value at each vertical axis value of the aspherical reference power profile W, the first region includes an inner first region having a power profile in which a positive power is added to a power profile Va for the first region; the second region has a power profile Vb; An intraocular lens, wherein the area of ​​the inner first region is less than 50% of the total area of ​​the first region.

33. When viewed in a radial direction from a lens center O, the first region includes an inner first region and an outer first region surrounding the inner first region, 33. The intraocular lens of claim 32, wherein the outer first region has a power profile Va and contacts the second region at an intersection of the power profiles Va and Vb.

34. 33. The intraocular lens of claim 32, wherein the lens body has two opposing surfaces and the inner first region is provided on the anterior surface, the posterior surface, or both.

35. The intraocular lens of claim 32, wherein the first region includes a region other than the inner first region whose average power is equal to the average power of the power profile Va, and the average power of the inner first region is 0.75 to 4.0 D greater than the average power of the region other than the inner first region.

36. 34. The intraocular lens of claim 33, wherein the first region comprises an outer transition region for joining the inner first region to the outer first region.

37. the inner first region includes a constant power addition region having a power profile in which a positive constant power is added to the power profile Va for the first region; The intraocular lens according to claim 32, wherein, when viewed in the radial direction from the lens center O, the radial distance of the fixed power addition region is 33 to 67% of the radial distance of the inner first region.

38. 33. The intraocular lens of claim 32, wherein the inner first region includes a lens center O.

39. the first region includes an innermost region having a power profile Va for the first region and including a lens center O; 34. The intraocular lens of claim 33, wherein the inner first region surrounds the innermost region.

40. 40. The intraocular lens of claim 39, wherein the first region comprises an inner transition region for joining the inner first region to the innermost region.

41. 33. The intraocular lens of claim 32, wherein the anterior surface, the posterior surface, or both of the lens body of the intraocular lens having two opposing surfaces are aspheric.

42. 33. The intraocular lens of claim 32, wherein the front surface, the back surface, or both of the lens body of the intraocular lens having two opposing surfaces has a toric surface with a cylindrical power for correcting astigmatism in an aphakic eye patient.

43. The intraocular lens according to any one of claims 1 to 42, which is made of at least one of silicone, hydrophobic acrylic resin, hydrophilic acrylic resin, hydrogel, PMMA, PMMA copolymer, and copolymer of HEMA (hydroxyethyl methacrylate) containing collagen.

44. A method for designing an intraocular lens, comprising the steps of: designing the intraocular lens according to any one of claims 1 to 42;

45. A method for manufacturing an intraocular lens, comprising manufacturing an intraocular lens designed by the method for designing an intraocular lens according to claim 44 by at least one of lathe, molding, and 3D printing.

Images