Delivery of fluid from syringe

Abstract

To provide an apparatus and method for delivering fluid from a syringe to a subject using a pumping device of a flow control apparatus.SOLUTION: The method includes locating a flow control apparatus 1 on a horizontal support surface and thereby providing a syringe 14 with a volume of fluid including a total amount of preferred nutrient and an amount of non-preferred nutrient liquid. The method further includes: mounting the syringe relative to the flow control apparatus whereby the syringe is oriented in a generally vertical orientation such that an outlet of the syringe faces upward; and initiating operation of the pumping device to draw the fluid from the syringe for a duration of time to preferentially deliver at least a portion of the total amount of preferred nutrient in the fluid to the subject.SELECTED DRAWING: Figure 1

Description

[Technical Field]

[0001] The present invention relates generally to delivering fluids from syringes, and more particularly to pump sets. a syringe stand, a syringe assembly, a flow control device, and a method for delivering fluid from the syringe and related methods for: [Background technology]

[0002] CROSS-REFERENCE TO RELATED APPLICATIONS This application is a continuation of U.S. Non-Provisional Patent Application No. 16, filed November 15, 2019, which is currently pending. / 686,002, which claims priority to the currently pending application dated March 7, 2019. This application claims priority to U.S. Provisional Patent Application No. 62 / 814,989 filed on Dec. 1, 2002, both of which are hereby incorporated by reference. No. 6,239,999, both of which are incorporated herein by reference in their entireties.

[0003] Administration of medicines or nutrients to patients who are unable to take medicines or nutrients orally should be performed using a peristaltic flow control system. Generally, in such systems, the fluid is , mounted on a flow control device such as a peristaltic pump that delivers fluid to the patient at a controlled delivery rate. It is delivered to the patient by a pump set containing flexible elastomeric tubing. The rotor typically has a housing containing a rotor that operably engages a motor through a gearbox. The rotor is impacted by one or more rollers on the rotor, e.g., by pinching. The peristaltic action caused by the reversible compression caused by the The rotor drives the fluid through a flexible tube. The rotation of the rotor drives the fluid at a controlled speed. The pump set gradually compresses the moving elastomer tube. It may have a valve mechanism to allow or prevent communication of bodily fluids. The volume control system also operates one or more motors to effectively control the flow of fluid. The controller may have a function to adjust the speed.

[0004] Peristaltic pumps work by delivering fluid in small amounts called "aliquots." The rotor engages the elastomer tubing of the pump set, For example, a portion of the tube may be picked up and positioned in front of the picking position, closer to the patient than the source of fluid going to the patient. Generally, the volume of fluid administered to the patient is such that each aliquot is substantially Count the number of aliquots that are the same volume and add that number to the desired total volume of fluid to be delivered. The flow rate is controlled within the pump by stopping when the corresponding volume is reached. It is extremely useful for administering medications and therapeutic fluids to patients because it is hygienic and generally accurate. do. Summary of the Invention [Means for solving the problem]

[0005] In one aspect, a method for delivering fluid from a syringe to a subject using a pump device of a flow control device However, this generally involves placing a flow control device on a horizontal support surface. A quantity of fluid containing an undesired nutrient solution is provided to the syringe. Attach the syringe to the syringe so that the syringe is in a generally vertical position with the outlet of the syringe facing upwards. The pumping device is turned on to draw fluid from the syringe for a period of time. At least 40% of the total amount of desired nutrients in the fluid is delivered by the pumping device from the syringe. The fluid should be delivered from the syringe within the first third of the time it takes to withdraw it. , delivering at least a portion of the amount of fluid from the syringe to the subject.

[0006] In another embodiment, a barrel having an outlet and a plastic container received in the end of the barrel opposite the outlet. A syringe stand for supporting a syringe including a syringe and a syringe holder is generally A syringe stand includes a base for supporting the syringe on a horizontal support surface. The holder is attachable to a base and allows the syringe to be positioned in at least two different positions. The base is selectively positionable relative to the base to orient the

[0007] In yet another embodiment, a pump is provided to deliver fluid from a source through a pump set to a subject. Flow control devices used with pump sets typically operate within the pump set during the delivery cycle. A pumping device is provided that can act on the pump set to generate a flow of fluid. A controller controls a pump in a delivery arrangement to generate fluid flow within the pump set. The controller is in communication with the pumping device to control the operation of the device. The controller stores the selected flow rate and the desired volume of fluid in the memory. The controller is configured to store the actual flow rate from the source from the selected flow rate. To take into account detected deviations in flow rate, the flow rate through the pump set during the delivery cycle is A supply time corrector for adjusting the supply time for operating a pump device for delivering the body is provided. It is configured to run within the

[0008] In yet another aspect, a device-mounted device for a flow control device including a pump system is provided. A support for engaging the pump set generally receives at least a portion of the flow control device. The base is configured to support the flow control device on a horizontal support surface. The flow control device is configured so that it is oriented generally horizontally. One adjustable leg allows for the alignment of the base relative to the horizontal axis when the base is supported on a horizontal support surface. The flow control device may be angularly oriented such that the flow control device is angularly oriented when received in the base. The actuator is configured to change direction by 10 degrees. [Brief explanation of the drawings]

[0009] [Figure 1] FIG. 1 is a perspective view of a feeding system including an enteral feeding pump, a pump support, a feeding set assembly, and a syringe.

[0010] [Figure 2] FIG. 1 is a fragmentary perspective view of a feeding system including an enteral feeding pump and a portion of a feeding set assembly.

[0011] [Figure 3] FIG. 3 is a perspective view of FIG. 2, but with a portion of the cassette removed.

[0012] [Figure 4] FIG. 1 is a front perspective view of an enteral feeding pump.

[0013] [Figure 4A] FIG. 1 is a rear perspective view of an enteral feeding pump.

[0014] [Figure 5] FIG.

[0015] [Figure 6] FIG. 10 is a perspective view of a cassette fitting.

[0016] [Figure 7] FIG. 10 is a front perspective view of a pump support and syringe of the feeding set assembly.

[0017] [Figure 8] FIG. 10 is a rear perspective view of the pump support and syringe.

[0018] [Figure 9] FIG. 10 is a perspective view of a syringe connector of the feeding set assembly.

[0019] [Figure 10] FIG. 10 is another perspective view of the syringe connector.

[0020] [Figure 11] FIG. 10 is a cross-sectional view of a syringe connector.

[0021] [Figure 12] FIG. 2 is a front perspective view of the pump support;

[0022] [Figure 13] FIG. 10 is a front perspective view of the base of the pump support.

[0023] [Figure 14] FIG. 10 is a front perspective view of the syringe holder of the pump support.

[0024] [Figure 15] FIG. 10 is a front view of the pump support with the syringe holder in a horizontal orientation.

[0025] [Figure 16] FIG. 10 is a front view of the pump support with the syringe holder in a vertical orientation.

[0026] [Figure 17] FIG. 17 is a front view of FIG. 16 showing the syringe loaded into the syringe holder and schematically showing breast milk in the syringe.

[0027] [Figure 18]FIG. 1 is a front view of a syringe stand with syringe holders at an angle.

[0028] [Figure 19] FIG. 1 is a block diagram illustrating components of an enteral feeding pump that can be utilized to implement one or more aspects disclosed herein.

[0029] [Figure 20] 1 is a graph showing the percentage of fat delivered at a given time over a breast milk delivery cycle for various syringe orientations.

[0030] [Figure 21] 1 is a graph showing the percentage of total depot fat delivered during a breast milk delivery cycle for various syringe orientations.

[0031] [Figure 22] FIG. 10 is a front view of another embodiment of a pump support.

[0032] [Figure 23] FIG. 23 is a rear view of the pump support of FIG. 22.

[0033] [Figure 24] FIG. 23 is an exploded view of the pump support of FIG. 22; and

[0034] [Figure 25] FIG. 10 is a front view of the pump support with the legs of the pump support pivoted to engage the support surface and orienting the pump support at an angle.

[0035] Corresponding reference numbers indicate corresponding parts throughout the drawings. DETAILED DESCRIPTION OF THE INVENTION

[0036] One or more aspects of the present invention are directed to peristaltic pumps, such as rotary peristaltic pumps, particularly those that are used to deliver blood to a patient (e.g., Accurately detect and control the amount of fluid delivered to a patient (baby) to maximize nutrient delivery to the patient Feed set assembly attachable to a rotary peristaltic pump to provide a fluid delivery device - Patent Application 20070122997 Any one or more features that provide or promote any one or more of these features. The advantageous features or structures may be implemented in peristaltic pumps used in a variety of commercial and industrial applications. Therefore, the detailed description will be directed to a supply set assembly including a cassette. Although directed to enteral feeding pumps, any one or more features of the present invention may be used in other peristaltic pumps. For example, the exemplary pump discussed may be a rotary peristaltic enteral feeding pump. Although the present invention is directed to other types of peristaltic pumps (not shown), including medical infusion pumps. Also, one or more of the various features and aspects of the present invention may be incorporated into the scope of the present invention. Without departing from the scope of the present invention, peristaltic pumps that use mechanisms other than rollers, such as linear peristaltic pumps, Additionally, a feeding set assembly (not shown) that does not include a cassette may also be implemented. may be used within the scope of the present invention.

[0037] Referring now to the drawings, and in particular to FIGS. 1-6, there is shown a block diagram of a system constructed in accordance with any one or more of the principles of the present invention. An exemplary enteral feeding pump (broadly a "flow control device") constructed as described above is generally designated 1. The supply pump is generally comprised of a supply set assembly (broadly referred to as a "pump"), generally designated 7. The entire assembly is configured to receive a cassette, generally designated 5, of the "cassette" ("cassette set"). The feeding set assembly 7 may include a housing generally designated by the reference numeral 3. It may include a syringe assembly 12 connected to the cassette 5 via a tube 77 . The cassette 5 of the supply set assembly 7 is removably mountable in the housing 3. In the illustrated embodiment, the cassette shell 9 of the cassette is The connector is removably received within a recess 6 (FIG. 4). The "housing" referred to herein is a multi-part structure and encloses or contains the working components of the pump 1. It may include many forms of support structure (not shown), including but not limited to structures that are not The pump 1 also displays information on the housing 3 about the status and operation of the pump. The display screen 10 can also display various aspects of the present invention. The feature can be implemented without recess 6. One or more buttons 11 may be provided adjacent to the display screen 10 for use in One or more light emitting diodes 13 can provide pump status information. Cut.

[0038] The display screen 10 may be part of the front panel (generally designated 19) of the housing 3. The enteral feeding pump may be removably attached to the housing. 19, generally designated 23, with a pump motor 27 (FIG. 19) connected to a pump motor (not shown). The pump unit (FIGS. 3 and 4) may further comprise a pump unit for supplying power to the pump motor. To this end, a battery (not shown) can be received within the housing 3. Or use a power source in addition to the battery to drive the pump unit via the rotor shaft A pump including one or more prime motors can be energized.

[0039] The pump unit 23 comprises a rotor (as a whole) that can be coupled to a rotor shaft. The rotor 37 has an inner disk 39, an outer disk 41, and The inner and outer disks are arranged to rotate relative to each other about their longitudinal axes. four rollers 43 (only three of which are shown) mounted between the The rollers 43 may be arranged to 3) of the supply set assembly 7 that forms part of the cassette 5. and delivers fluid to the subject through the feeding set assembly 7. For example, a nutrient solution (e.g. , breast milk and / or fortifiers) is delivered using a pump 1, a cassette 5, and a feeding set assembly 7. Other fluids may be delivered to the infant using pump 1 without departing from the scope of this disclosure. In the illustrated embodiment, the fluid in the syringe 14 can be delivered using a pump unit 23 However, the present invention is not limited to the above embodiments. In some embodiments, fluid from the syringe 14 is injected into the syringe barrel, for example by pushing a plunger. It has equivalent uses when delivered from a syringe in other ways, such as by squeezing.

[0040] 5 and 6, the cassette shell 9 has a front portion 53, a rear portion 55, an upper portion 57, and a The cassette body 51 has a bottom wall 59 and a side wall 61 and a top wall 63. A rear cavity extends from the rear 55 of the 51 and is configured to receive a fitting 65. The tube 45 is removably attached to the fitting 65. The fitting 65 can be attached to the cassette or may have a tab 88 that allows it to snap together. The fitting may be removably secured to the cassette.

[0041] Referring to FIG. 6, fitting 65 includes a base 67, an inlet port 69, and an outlet port 69. Inlet port 69 is a first port for insertion into the inlet end of tube 45. a first mounting portion 73 and a pair of second mounting portions for receiving inlet tubes 77 (FIG. 3); The outlet port 71 may include portions 75A and 75B. a first attachment portion 79 for engagement or attachment, such as by insertion of an outlet tube 83; a second attachment portion 81 for attachment to the outlet tube 83, such as by receiving a The second attachment portion 75A may include a supply source (e.g., syringe 14) and a flow The second attachment portion 75B can be connected to a cleaning source via an inlet tube 77. (e.g., a cleaning fluid bag). Alternatively, the second attachment The first fitting 75B can be attached to a supply source and the second fitting 75A can be attached to a cleaning source. Alternatively, the fitting 65 may be integrally formed with the cassette body 51 or may be omitted. In addition, the supply of nutritional liquid (e.g., breast milk) can be completed through the second attachment portion 75A. The second attachment part 75B is then used to draw air through the breast milk line. The second fitting 75B is open to the atmosphere to allow for a cleaner line. This prevents milk from remaining in the tube and going to waste. The attachment portions 75A and 75B can be swapped, so that the breast milk flows through the second attachment portion 7 5B, and the cleaning operation may be performed by a second attachment portion without departing from the scope of this disclosure. It will be understood that this is done through 75A.

[0042] Inlet tube 77, tube 45, fitting 65, and outlet tube 83 are provided. Cassette 5 is considered part of supply set assembly 7 for the purposes of this description. Syringe 14 is also considered part of supply set assembly 7. However, it may be possible to include more or fewer components than those described herein. Any feeding set assembly including the above is within the scope of the present invention.

[0043] In a preferred embodiment, the cassette shell 9 is made of a polymer material such as polycarbonate. 3 and 4, the cassette shell 9 and the tube 45 are made of the cassette. An insert 105 is provided in the cassette recess in the housing 3 to help secure it in the recess. 6. The insert 105 is inserted into the housing 3 when the cassette is installed. The insert 105 is inserted into the recess 6 so as to be received in the rear cavity of the cassette shell 9. The insert 105 may be positioned to receive the inlet portion of the tube 45. a pair of opposing first protrusions 107 disposed on the inlet side of the port, and a pair of first protrusions 108 disposed on the inlet side of the port for receiving the outlet portion of the tube; and a pair of opposing second projections 109 disposed on the outlet side of the insert for The mark 112 indicating the direction of fluid flow in the tube 45 is formed on the second protrusion 109. In the illustrated embodiment, the indicia 112 are in the form of arrows.

[0044] 1 and 7-11, a pump support is generally indicated at 16. The pump support 16 includes a base 60 for supporting the pump support on a horizontal support surface such as a tabletop. a syringe holder 62 attached to the base for securing the syringe 14 to the base; The syringe 14 and the syringe holder 62 constitute the syringe assembly 12. Pump support 16 connects syringe 14 to pump 1 when the pump is attached to the pump support. More specifically, as described in more detail below, the pump support 16 is configured to orient the syringe in a plurality of angular orientations. 6 is a holder that receives and supports the syringe 14, and also mounts and / or supports the pump 1. It may be configured as a syringe stand so as not to

[0045] Syringe 14 includes a barrel 18, which may be graduated, and a syringe slidably received within the barrel. In the illustrated embodiment, the syringe 1 may be a conventional syringe including a plunger 20. 4 includes external threads 26 and defines an outlet 28 and a tip passageway that communicates with the interior of barrel 18. It includes a female tip 24. The female tip 24 is centered about the longitudinal axis LA of the syringe 14. Syringe 14 may have other configurations without departing from the scope of this disclosure. For example, syringe The syringe is fitted with an eccentric tip so that the female tip is positioned off-center along the longitudinal axis of the syringe. Still other syringe configurations are contemplated within the scope of this disclosure.

[0046] 1 and 9-11, syringe connector 30 connects syringe 14 to inlet tube 7. 7 to fluidly connect the syringe to the inlet tube. The connector body 3 includes a one-piece, integrally formed molded connector body, generally designated 34. 4 is a syringe connector adapted to removably connect to the female tip 24 of the syringe 14. 38 and the end of the inlet tube 77 to connect the output of the syringe to the inlet port of the cassette 5. a tube connection portion 40 that is in fluid communication with the second attachment portion 75A of the valve or plug; a valve portion configured to receive the lug 47 to remove the supply fluid from the syringe after delivery; 41. The syringe connection portion 38 is adapted to fit the female tip of the syringe 14 when inserted into the tip passage. The syringe includes a male component 42 configured to form a fluid-tight seal with the end 24. An outer skirt 44 of the vessel connecting portion 38 surrounds the male component 42 and the female tip The stud 24 includes internal threads 46 configured to mate with the external threads 26 .

[0047] Syringe connector 30 defines an air passageway 50 and an enteral fluid passageway 52, respectively. Fluid passage 52 fluidly connects the interior of barrel 20 with inlet tube 77. Air passage 50 , as described in more detail below, inlet tube 77 is fluidly connected to the atmosphere. The enteral fluid passageway 52 is configured to remove fluid from the syringe connector 38. a first portion extending through the mold component 42 generally along the axis A1 of the connector body 34; The second portion 52b of the enteral fluid passageway 52, which leads to the inlet tube 77, has a first portion 52a and through the tube connection portion 40, which is generally perpendicular to the axis A1 of the connector body. The air passage 50 extends along the axis A1 of the connector body 34 through the valve portion 41. The second portion 50a of the air passage 50 leads to the inlet tube 77. b is a tube connection portion that is substantially perpendicular to the axis A1 of the first portion 50a and the connector body; 40. A second portion 50b of the air passage 50 follows the same passage through the connector 30. It coincides with the second portion 52b of the enteral fluid passageway 52 so as to occupy it.

[0048] Valve 47 is received in valve portion 41 of syringe connector 30 and connects air passage 50 to atmosphere. With the valve 47 received in the valve portion 41, during normal operation of the pump 1 whereby rotation of rotor 37 rotates syringe 14 to draw fluid from the syringe. However, a vacuum is created within the barrel 20 of the syringe 14. Even after the pumping, there may be fluid remaining in the inlet tube 77 that has not been pumped to the target. To deliver this portion of the fluid, valve 47 is opened, thereby opening air passage 5. 0 can be connected to the atmosphere. The atmosphere then flows through the air passage 50 and the inlet tube 77. This forces the fluid in the tubing through the line to the target. This ensures that all enteral fluid in vessel 14 is delivered to the subject. can be closed for subsequent delivery. In one embodiment, the valve 47 is When the pressure difference between the inside of the connector and the atmosphere reaches at least 8 psi, air is introduced into the connector 30. , and one-way check valves such as duckbill valves. In one example, the pressure differential is about 8 psi to about 10 psi. When the rotor 37 reaches the position between the rotor 37 and the valve 47, the valve 47 can be opened. The tube 45 is rotated to an unobstructed position, and the air forces the fluid past the rotor. The body 34 of the syringe connector 30 can be broadly defined as an inlet. The valve 47 may be considered a valve housing containing the valve 47 for removing fluid from the outlet tube 77. This can be done.

[0049] 12 and 13, the pump support 16 is configured to support the pump on a horizontal support surface such as a tabletop. a base 60 for supporting the support body, and a syringe 14 for securing the syringe 14 to the pump support; The holder 62 is attachable to the base 60 and holds the syringe 1. 4 selectively relative to the base to orient the pump support 16 in a number of different configurations. For example, the pump support 16 may be positioned such that the syringe is oriented generally horizontally. A first configuration (FIG. 15) in which the syringe is oriented generally vertically, and a second configuration (FIG. 16) in which the syringe is oriented generally vertically. 6) and the syringe 14. The pump support 16 is configured to orient the syringe 14 to the The syringe 14 is placed in a third orientation (FIG. 18) oriented at an angle between the horizontal and vertical directions. The pump support 16 may also be configurable to orient in a horizontal and vertical direction. It may be configurable to direct the syringe in further directions between

[0050] The base 60 has a flat bottom surface 64 for resting the base on a horizontal support surface. Thus, the base 60 itself changes its angular position relative to the horizontal axis when it is resting on a horizontal support surface. A rear wall 66 extends upward from the bottom surface 64 to secure the pump 1 to the base 60. A pair of side walls 68 extend laterally from the rear wall 66 and support the pump mounted to the base 60. The rear wall 66 and the side walls 68 are opposite to both sides of the pump 1 when the pump 1 is installed. A mount 101 can be disposed on the rear wall 66. In an embodiment, the mount 101 has a rounded triangular or arched shape. The mounting flanges of the mount 101 include a mounting flange 103 that branches off on both sides of the mount. 103 slides into groove 136 (FIG. 4A) formed on the back of pump 1, The post 111 can be configured to attach the mount 1 to the base 60. 1 and 2. The pump 1 can be positioned on the rear wall 66 within the periphery of the base 60 to lock the pump 1 to the base 60. The rear wall 66 may have a receptacle for receiving a retainer (not shown) for the retainer. A notch 120 forms a handle on the base 60 for carrying the pump support 16. Wall 66 is attached to holder 62 and positions the holder relative to base 60 . In the illustrated embodiment, a plurality of holes 117 are formed in the rear wall 66 to secure the holder 62 to the base 60. The holder 62 is configured to receive fasteners 74 for attachment to the base 60. It is understood that other means for attaching to the device may be utilized without departing from the scope of this disclosure. It will be done.

[0051] A feedthrough connector 76 is formed on the rear wall 66 within the cutout 120 and extends through the rear wall 66. The through connector 76 is a protrusion that extends forward on the connector 76 and enters the receiving space 70. A port 80 is formed in the rear side of the connector 76 and at least partially The port 80 extends through the connector and transmits power and data from the port to the plug. Thus, the connector 76 is electrically connected to the plug 78 so that the data can be transferred therethrough. The plug 78 is configured to connect to a port 82 on the back of the pump 1 (FIG. 4). A). Port 80 on base 60 is connected to port 8 on pump 1 by plug 78 on the pump support. 2, power from the power cord is transmitted to both the pump support 16 and the pump 1. The power cord is configured to receive a plug (not shown) of a power cord so that the power cord can be easily inserted into the power supply. In this embodiment, the through connector 76 is integrally formed with the base. The connector 76 may be formed separately from the base 60 and suitably attached to the base. A USB or other suitable connector (not shown) may be provided on the base 60. The actuator is configured to transfer data to the pump support 16 and the pump 1. For example, Software updates are communicated to the pump support 16 and pump 1 via the USB connector. In one embodiment, the USB connector is formed as part of the feed-through connector 76.

[0052] 12 and 14, syringe holder 62 includes a floor 86 and a rear wall extending from the floor. 88 and opposing side walls 90 extending laterally from the rear wall away from the floor. 88 and sidewall 90 together define a receiving space 92 for at least a portion of syringe 14. A first pair of flanges 94 are attached to each side wall 90 of the holder 62 near the top of the holder. Each side wall 90 extends from a first flange pair 94 above the flanges 94. The syringe 14 has a recess 99 that forms a second pair of flanges 96 spaced longitudinally from the first flange 96. A portion of the barrel 18 is received between a first pair of flanges 94 and a second pair of flanges 96. The flanges 94, 96 support the barrel 18 within the holder 62 along an axis parallel to the rear wall 88. A pair of rails 98 are provided between the floor 86 and the first pair of flanges 94 to prevent lateral movement of the A U-shaped plate 100 is fixedly disposed on the upper end of the rail 98, and the rail A U-shaped slide 102 is disposed around the bottom end of the A gap is formed between the first flange pair 94 and the U-shaped plate 100. The gap 104 is formed between the flange 58 of the barrel 18 of the syringe 14. The length of the gap 104 is greater than the thickness of the flange 58 (FIG. 7). This allows the flange 58 to be spaced apart from the flange 94 and the plate 100. The barrel is held stationary, thereby resisting longitudinal movement within the holder 62. When the syringe 14 is received in the holder 62, the plunger 20 A flange 44 is held between the lever 121 and the slide 102. For example, the lever 12 1, rotate the lever to the left as shown in Figure 14 and slide it down the rail 98 to Operable to provide clearance for plunger flange 44. The U-shape of the plunger 20 and the plate 100 is adapted to receive the rod of the plunger 20 therein. Then, rotate the lever 121 back to the right and return the lever to the rail. 98 to secure the plunger flange 44 to the slide 102. As will be explained in more detail below, the syringe 14 may be withdrawn from the barrel 18. The fluid moving in moves the plunger 20 away from the floor 86. The movement of the plunger 20 The slide 102 on the rail 98 is adapted to move the ranger along a substantially linear axis. Alternatively, the syringe holder may be configured to guide the longitudinal position of the plunger 20. The barrel 18 moves relative to the plunger as fluid is drawn from the barrel. The device may be configured to allow the device to:

[0053] A door or gate 106 is attached to one of the first flange pair 94 and one of the second flange pair 96. and the syringe 14 is pivotally mounted between the receiving space 92. The door is movable between an open position for holding the syringe in the receiving space and a closed position for holding the syringe in the receiving space. A sensor 108 (FIG. 1) is provided to detect the position of the door 106 after it has been moved to the closed position. 14) may be provided in the holder 62. Based on the position of the door 106, the size of the syringe 14 may be For example, pre-programmed sizes stored in memory 93 can be used to measure the size. In response to the door 106 being placed in a predetermined position indicating the size of the syringe 14 as the size of the syringe 14. The controller 72 (FIG. 19) in the pump 1 then issues a prompt requiring confirmation by the user. Alternatively, the controller 72 may initiate a call based on the position of the door 106. The size of the syringe 14 can be automatically measured by the connecting arm 110. It extends from one side and is configured to attach the holder 62 to the base 60. Specifically, The connecting arm 110 has fasteners 74 passing through holes to attach the holder 62 to the base. 60. The base 60 includes a plurality of holes 113 corresponding to the holes 117 in the rear wall 66 of the base 60 so that the base 60 can receive the .

[0054] 1 and 14, a sensor located on rear wall 88 for detecting movement of plunger 20 is provided. A position sensor 115 may be attached. In the illustrated embodiment, the position sensor 115 is , a linear resistance potentiometer. The contacts 114 of the potentiometer 115 are The contacts are arranged on the movable part of the holder 62, such as the slide 102, and the contacts are moved by the movement of the slide. The barrel 18 is fixed in the holder 62 and moves along the meter 115. The plunger 20 is held in a fixed position so that as fluid is drawn from the barrel, The flange 44 of the plunger 20 prevents the plunger from moving into the barrel 18. , engages with slide 102 and moves the slide along rail 98. Thus, in this embodiment, movement of contact 114 is sufficient to draw supply fluid from syringe 14. the plunger against the barrel 18 and holder 62 caused by the In other words, the movement of the contact 114 represents the movement of the plunger 20. The cross-sectional area of ​​the internal cavity of the barrel 18 corresponds to the syringe size. Since it is known from the detection of 4. Specifically, the syringe 14 Knowing the inside diameter of the barrel 18, the distance the slide 102 / plunger 20 has traveled can be calculated. In combination with the potency, the amount of fluid delivered from the syringe 14 can be measured. The potentiometer 115 receives a position signal from the potentiometer 115 indicating the movement of the slide 102. The controller 72 may be electrically connected to receive the It may be located within the pump 1 or may be located remotely from and in communication with the pump 1. For example, the controller 72 may be located within the pump support 16. In an embodiment, the plunger 20 is held stationary and the barrel 18 moves relative to the plunger. In the configuration, movement of the contacts represents movement of the barrel 18 .

[0055] Other position sensors are contemplated without departing from the scope of this disclosure. For example, a linear magnetic A resistor potentiometer (not shown) can be used. The contactor is attached to the slide 102 or alternatively to the plunger 20. It can be attached to a structure to measure the movement of the slide / plunger. The electromagnetic contactor attached to the pump system has a magnetic contactor. Additionally, an inductive position sensor (not shown) can be used. In yet another embodiment, a camera (not shown) is used to measure the movement of plunger 20. In this embodiment, any point on the syringe 14 (e.g., The movement of the jar 20 is tracked using image analysis software that communicates with the camera. The size of the syringe 14 can be automatically detected using a camera and imaging software. In yet another embodiment, a foil sensor or a non-magnetic sensor may be used. In a further embodiment, the amount of fluid delivered may be measured by weight detection. The examples of detection devices are not intended to be exhaustive as they fall within the scope of the present invention.

[0056] The exemplary feeding set assembly 7 is configured for metered fluid delivery using an enteral feeding pump 1. It can be used in enteral feeding of newborns to achieve this. In such a way, the enteral fluid , is drawn into the syringe 14 by pulling back on the plunger 20. The amount of enteral fluid is This can be measured using the graduation marks on the barrel 18 of the syringe 14. After filling with an appropriate amount of enteral fluid, the syringe connector 30 connects the syringe connection portion 38 to the syringe tip. It can be attached to the syringe tip 24, such as by threading it onto the end 24. The tube connector 40 can also be connected to the inlet tube 77. Prior to installation in the housing 3, the inlet tube 77 can be connected to the outlet port 69. 1, the outlet tube 83 can be attached to the outlet port 71 of the cassette 5.

[0057] To mount the cassette 5 in the pump housing 3, the cassette shell 9 is One or more pins or raised projections 119 (FIG. 5) on the lower portion 59 of the body 51 are inserted into the housing. 3 and 4. The engagement between the recessed projections 119 and the slots 124 generally holds the cassette shell 9 in place. The cassette body 51 is then placed on the tab 57 at the top of the cassette body. 125 until the ledge 123 of the recess 6 is caught by the catch 127 at the top of the recess 6. The cassette 5 can be rotated in the opposite direction (Fig. 2 and Fig. 4). To remove it, tab 125 can be depressed to release shelf 123 from catch 127. When the cassette 5 is attached to the pump housing 3, the tube 45 1 roller 43 is positioned to engage.

[0058] The pump support 16 is configured to position the syringe holder 62 in a number of different angular orientations. The pump 1 and the base 60 of the pump support can be received in a syringe holder. The syringe 14 is supported horizontally on a support surface S for positioning the syringe 14 in a corresponding angular orientation. Orienting the syringe 14 in a particular direction can reduce the amount of fluid in the syringe early in the dispensing cycle. In one embodiment, the injection may be advantageous for delivering certain desirable nutrients in a volume of fluid. The syringe 14 is selectively positionable horizontally (FIG. 15) to adjust the length of the syringe. The manual axis LA is oriented generally parallel to the horizontal axis when the syringe is received in the holder 62. This is done by first attaching the connecting arm 110 of the holder 62 to the rear wall 66 of the base 60. 117 in the rear wall in the first alignment direction. In one embodiment, the syringe 14 is selectively positioned vertically. 16, so that the longitudinal axis LA of the syringe is aligned with the holder 62. The syringe is oriented generally parallel to the vertical axis so that the tip 24 of the syringe faces upward when received in the syringe. This is because the connecting arm 110 of the holder 62 is first connected to the rear wall 66 of the base 60 (FIG. 17). The connecting arm is attached at a second attachment position different from the first attachment position, and the hole 113 of the connecting arm is inserted in the rear. This is done by aligning the syringe 14 with the hole 117 in the wall in the second alignment direction. If the nutrient solution being injected is, for example, breast milk M, the tip 24 of the syringe can be pointed upward. This allows the contents of breast milk M to naturally separate, causing the fat F in breast milk M to rise to the top of the mixture. 2, thereby causing the fluid closest to the outlet 28 of the syringe 14 to rise to the non-fat liquid portion of the breast milk. Therefore, fat, which is the most important part of breast milk, is located near the F is delivered to the infant first. This is done by holding the syringe so that the barrel 18 is oriented horizontally. This does not occur when the tip 2 is positioned. In this orientation, the fat F of the breast milk M flows into the tip 2. In a horizontal orientation, the watery portion of breast milk tends to pool at the top of the barrel 18, away from the The sexual contents are delivered first. Often, newborns tolerate only a small amount of milk per feeding. Therefore, it is important for newborns to consume as much fat as possible as soon as possible while breastfeeding. It is important to ensure that the nutrients other than fat are oriented vertically with the tip pointing upward. It is expected that the vitamins in the nutrient solution can be preferentially delivered by the syringe 14 provided. The hydroxyl and / or minerals may be preferentially delivered in this angular direction.

[0059] Pump support 16 is also configured to orient syringe 14 at other angular orientations. In one embodiment, the syringe 14 is selectively positionable in an oblique direction (FIG. 18). This allows the longitudinal axis LA of the syringe to be aligned with the tip of the syringe when received in holder 62. 24 is tilted upward and is disposed obliquely relative to the vertical and horizontal axes. The connecting arm 110 of the holder 62 is attached to the rear wall 66 of the base 60 at the first and second attachment positions. and aligning the hole 113 of the connecting arm with the hole 117 in the rear wall. This is accomplished by aligning the syringe 14 in the alignment direction of the syringe 14. This also allows for natural separation of the contents of the breast milk in the syringe. The syringe is oriented at an angle of approximately 40 degrees to the horizontal axis. 4 may be positioned at other angles without departing from the scope of this disclosure. In this embodiment, the syringe 14 may be oriented at an angle between about 20 degrees and about 60 degrees relative to the horizontal axis. In one embodiment, the syringe 14 is angled between about 20 degrees and about 40 degrees relative to the horizontal axis. The angle can be adjusted to any desired angle.

[0060] In one embodiment, the pump support 16 is attached to a vertical support, such as an IV pole. The syringe 14 can be oriented in a second perpendicular direction such that the longitudinal axis L of the syringe A is generally parallel to the vertical axis so that the tip 24 of the syringe faces downward. The support 16 can be set in any of the angular orientations shown in Figures 15, 16, and 18. , can be attached to an IV pole by a mount 129 on the back of the pump support. The pump support 16 is then manipulated (e.g., rotated or rotated) to inject the syringe 1 4 can be oriented so that it extends vertically with tip 24 pointing downward. Orienting syringe 14 in this manner facilitates delivery of the fortifying agent within syringe 14 to the infant. This is because the nutrients in the fortifier sink to the bottom of the barrel 20 of the syringe 14. Therefore, when the tip 24 of the syringe 14 is positioned at the bottom of the syringe 14, nutrients from the fortifying agent are Nutrients are delivered first. Also, the pump support 16 is at the angle shown in FIGS. Operate the pump support while it is set in one of the directions and attached to the vertical support. This allows the syringe 14 to be oriented in any desired angular direction.

[0061] In one embodiment, the pump support 16 may be configured to: The syringe holder 62 is configured so that it cannot be turned around. The vessel holder 62 must remain in the selected orientation after the pump 1 is started. Therefore, to change the orientation of the syringe holder 62, the pump 1 must be attached to the pump support. 16 and syringe holder 62 is removed from base 60. In one embodiment, a tool is required to reposition the pump support as desired. 16 is used in the biotechnology department of a hospital or It must be returned to the manufacturer.

[0062] 20 and 21, when delivering breast milk to an infant, the tip 24 of the syringe is It has been found that directing the fat delivery to the target tissue significantly increases fat delivery during the initial phase of delivery. In a comparative study, a center-tip syringe filled with breast milk was administered at different times during the feeding cycle. The device was oriented at various angular positions and the amount and time of fat delivery was monitored throughout the delivery process. In particular, in this study, the syringe tip was tilted horizontally with respect to the horizontal plane, with the tip pointing upward. At a 25-degree angle, hold the syringe at a 45-degree angle to the horizontal with the tip pointing up. In a vertical orientation, the syringe is placed at a 90 degree angle to the horizontal with the tip pointing upwards. and vertical syringes, in which the syringe is placed at a 90-degree angle to the horizontal with the tip of the syringe pointing downwards. The delivery of breast milk was monitored with the syringe held in a vertical position. Syringes oriented with the tip pointing up will collect more of the fat in the milk early in the delivery cycle. Conversely, syringes oriented with the tip pointing downwards delivered a larger proportion of the delivered the lowest percentage of the fat portion of breast milk early in the delivery cycle.

[0063] Each syringe feeding cycle lasted 60 minutes. The vertical orientation of the injector, with the tip facing up, delivers the fat content of breast milk during the early stages of the lactation cycle. Referring to Figure 21, within the first 20 minutes of the lactation cycle, In one embodiment, more than 40% of the total fat in breast milk was delivered. More than % of the dose was delivered within the first 20 minutes. Each volume of breast milk delivered contained greater than 10% fat (Figure 20). For at least 5 minutes within the first 20 minutes, each volume of milk delivered contains more than 10% fat. All other orientations failed to restore these fat delivery capabilities within the first 20 minutes of the delivery cycle. I couldn't manifest it.

[0064] Referring to Figure 21, within the first 30 minutes of a feeding cycle, 60% of the total fat in breast milk In one embodiment, more than 63% of the total fat was delivered in the first 30 minutes. and within a portion of that time, each volume of breast milk delivered increased by more than 10%. In one embodiment, the fat content of the sucrose solution was at least 100 mg / kg / day within the first 30 minutes of delivery (Figure 20). For 10 minutes, each volume of milk delivered contained more than 10% fat. These fat delivery capabilities could not be replicated within the first 30 minutes of the delivery cycle.

[0065] Referring to Figure 21, within the first 40 minutes of a feeding cycle, 65% of the total fat in breast milk In one embodiment, more than 70% of the total fat was delivered in the first 40 minutes. In one embodiment, greater than 71% of the total fat was delivered within the first 40 minutes. More than 80% of the total fat in breast milk was delivered within the first 50 minutes of a feeding cycle. In one embodiment, greater than 84% of the total fat was delivered within the first 50 minutes. Ultimately, by the end of the lactation cycle, more than 90% of the total fat was delivered. In one embodiment, greater than 94% of the total fat is delivered by the end of the lactation cycle. was done.

[0066] The syringe 14 is loaded into the holder 62 of the pump support 16 and attached to the tube 77. Once attached, Pump 1 is configured to deliver the supply of fluid within the syringe to a subject. This action causes the roller 43 to engage with the tube 45 in the cassette shell 9, discharging the syringe 1 The supply fluid is pumped from 4 to the target. The engagement of the tube 45 by the roller 43 The syringe is then placed vertically with tip 24 facing upwards. When the pump support 16 is configured to be oriented in such a way that gravity pulls the supply fluid from the syringe. The plunger 20 does not assist in the withdrawal and forces the fluid upward from the barrel 18. Therefore, the rotor 37 rotates and the roller 34 rotates the tube 45. When occluded, air, rather than liquid, will first exit the inlet tube 77 and barrel 18 of the syringe 14. After a sufficient number of rotor revolutions, the inlet tube is drawn out of the syringe, creating a vacuum. A vacuum is created within pump 77 and syringe 14. Continued rotation of rotor 37 causes pump The supply fluid is pumped by pump 1 into outlet tube 83 to the target from barrel 18. 9 through inlet port 69 and tube 45 into inlet tube 77. However, the rotation of rotor 37 causes gravity to expel the dispense fluid downward from the syringe. As in the case of conventional pump devices, where the syringe outlet is oriented to aid in It does not result in a continuous and uniform flow of the supply fluid through the supply set 7. On the contrary, the fluid is supplied in an insufficient amount. Regularly, time is withdrawn from the syringe 14 in discrete portions or increments. During the first period of rotation, no fluid is drawn from the syringe 14. During this period, the plunger 2 0 remains stationary relative to the barrel 18. Finally, a valve is opened that creates a vacuum in the fluid line. Rotation of rotor 37 draws a first amount of fluid from syringe 14 that is delivered to the subject. The plunger 20 swings further into the barrel 18 as the first increment is delivered. The pump motor that drives the rotor rotation stops. The actuation of the plunger is sufficient to move the plunger 20 (for example, but not limited to). (not related to the delivery of at least about 0.1 ml of fluid) When movement is detected, a delay is applied before the plunger stop position is read. There is a time limit for the rotor 37 to stop rotating. This stops the vacuum pressure from building up in the supply line and helps prevent the formation of air bubbles. As explained more fully in, the rotor is stopped from rotating for a period of time, and then it starts rotating again. However, the continuous rotation of rotor 37 provides a constant flow rate of fluid from syringe 14. Instead, fluid is drawn from the syringe 14 while the rotor 37 is rotating. A second period of time passes during which no pressure is applied. Finally, this further rotation of rotor 37 causes the pump The plunger 20 again swings forward within the barrel 18, dispensing a second portion of the fluid from the syringe 14. This process continues throughout the feeding cycle. The amount of fluid drawn from the syringe 14 in the chamber is proportional to the duration of the fluid withdrawal. Therefore, in order to deliver a predetermined amount of nutrient solution to a subject, the pump 1 A delivery time calculation is performed that takes into account the nonlinear fluid delivery that is produced.

[0067] Pump 1 can be programmed or otherwise controlled to operate in a desired manner. For example, pump 1 begins operation to deliver delivery fluid from syringe 14 to the subject. A user, such as a caregiver, can control the amount of fluid delivered, the fluid flow rate, and the fluid delivery rate. The pump 1 may be configured with a microprocessor 89 or the like to select the frequency of the pump. The controller 72 (FIG. 19) may include a processor, which may The PC1 accepts programming and / or has pre-programmed functions that can be initiated by the user. It allows for programmed operating routines, e.g., algorithms, to be included. Roller 72 also controls the pump motor to operate rotor 37. 27.

[0068] The amount of delivery fluid delivered to the subject is typically adjusted in a counterclockwise direction (as seen in Figure 3). In the illustrated embodiment, the rotor 37 is rotated by the rotation speed of the rotor 37. The rotor 37 is configured with three rotors so that one aliquot of fluid is delivered to the target every third of a rotation. When each roller 43 first engages the tube 45, the roller 43 pinches the tube, thereby directing fluid from the source forward (i.e., toward the subject). The roller 43 continues to rotate counterclockwise, thereby isolating a certain amount of fluid. The picked volume of fluid in front of the roller, e.g., an aliquot, is pushed towards the target. Finally, the trailing roller picks up the tube to deliver the next aliquot of fluid. At approximately the same time as the leading roller 43 engages the tube 45, the leading roller 43 disengages from the tube 45. Thus, the microprocessor 89 issues commands to deliver the selected fluid flow rate. Upon receiving the flow rate, the flow rate is typically adjusted to a predetermined time to deliver multiple aliquots that produce the desired flow rate. The selected flow rate is input by a doctor, nurse, or other caregiver. or the selected rate or default delivery rate preprogrammed into Pump 1 It can be.

[0069] However, as described above, the rotor 37 is in operation and the tip 24 is facing upward. When the injector 14 is oriented vertically, the pump 1 does not produce a constant flow rate of fluid. Rather, the nutrient solution is administered in multiple portions or increments that are almost always uneven in volume and time. The syringe 14 is then drawn. Therefore, the controller 72 controls the timer 91 and the supply The portion of fluid that is drawn from the syringe after a certain time has elapsed during the cycle is programmed. memory area 9 containing a delivery time corrector 85 that adjusts the delivery time in the event of deviation from the specified flow rate; In the illustrated embodiment, the supply time corrector 85 may include a supply time corrector 3. The supply time correction command 95 may include a supply time correction function 97. These are machine-readable instructions on any suitable medium, commonly known as memory area 93. The instructions may be executed by the microprocessor 89. A timer 91 may be configured to A supply cycle (broadly, an "operating cycle") is initiated or When the supply cycle is to be executed, it can be started in an appropriate manner. This information, along with additional parameters, can be used to determine the potential of the feed fluid delivered during the delivery cycle. This allows for correction of potentially non-uniform amounts.

[0070] The delivery time compensator 85 determines the amount of time that is drawn for the syringe 14 while the pump 1 is operating in the delivery phase. To account for deviations in the amount of fluid delivered to the subject through the feeding set 7, The adjustment function can be operable to adjust the duration for delivering the supply fluid. The number may be a selected or pre-programmed flow rate for the delivery fluid, the amount of fluid delivered to the subject, or This may depend on the amount of fluid dispensed and the time that Pump 1 has been running during the dispense cycle. More specifically, the controller 72 calculates the adjusted or corrected delivery time using the following function: The interval can be determined. X = (Y + Yl) / (Z + Zn) X is the selected flow rate for the dispense fluid during the dispense cycle. Y is the flow rate from the syringe 14. The amount of dispense fluid that has been withdrawn and taken into account in all previous correction calculations in the dispense cycle. Yl is the amount of dispensed fluid drawn from syringe 14 since the last correction calculation. Z is the total time elapsed from the start of the dispense cycle to the start of the dispense correction action. is the adjustment or correction supply cycle time that is added to the total supply cycle time. When one or more of the numbers is entered into Pump 1 by the caregiver (or when a pre-programmed When included in the supply configuration, the microprocessor 79 calculates the value of Zn = (Y + Y1 - XZ) / X. Therefore, the adjustment Zn of the supply time is stored in the controller 72 so that it can be calculated. The supply time corrector 85 is used to calculate Zn=(Y+Y1-XZ) / X. In one embodiment, the calculation of the delivery time is performed by Each portion or increment of fluid is withdrawn from syringe 14 while rotor 37 is stopped from rotating. The supply correction function 97 then adjusts the actual fluid flow rate to the selected fluid flow rate. The operation of pump 1 is suspended for a period of time Zn to allow the temperature to approach .

[0071] In practice, the amount of fluid delivered to the barrel 18 may be greater than the amount of fluid delivered to the barrel 18 before a significant amount of fluid is delivered. There may be some very small movements of the plunger 20. In one embodiment, these Smaller movements are ignored. In other words, the dispense time corrector 85 adjusts the dispense time to match the threshold amount of dispense fluid. The delivery time correction calculation may not begin until the syringe 14 is withdrawn. For example, the delivery time correction calculation is performed when a fluid-related movement of at least about 0.05 ml is detected. The threshold for the start of the supply time correction calculation is as follows: For example, but not limited to, the threshold value may be other than Although it may be in the range of 1 ml, 2 ml or more.

[0072] Additionally, by using a "wobble-and-go" fluid delivery approach, the syringe can be moved This creates a system that creates only the minimum amount of vacuum necessary to create the smallest possible vacuum. Its use significantly reduces and in some cases eliminates the formation of bubbles in the liquid. Having air bubbles suspended in the body can undesirably lead to errors in the overall measurement accuracy.

[0073] Additionally or alternatively, delivery time corrector 85 may be configured to calculate the value of Y+Y1 (previously withdrawn from syringe 14) The amount of fluid dispensed plus the most recent increment is used to determine the amount of fluid dispensed to the subject. If Y is within a predetermined range of the desired total amount, the supply size For example, if Y is within 0.1 ml of the desired total volume, the lactation cycle is stopped. Other ranges (e.g., 0.05 ml, 0.15 ml, 0.2 ml, 0.25 ml, 0.3 ml, etc.) may be used.

[0074] Detecting the position of the plunger 20 of the syringe 14 relative to the stand 16 and barrel 18 In embodiments where a camera is used to select an arbitrary reference point on the plunger, and determining the length of the movement by monitoring the changing position of the selected reference point. As previously described herein, the camera calibrates the linear motion with the amount of fluid delivered. The syringe type (e.g., However, it can also be used to detect the specific injection site (e.g., brand or size). If the inner diameter of the vessel barrel is unknown, the calibration of the controller 72 is performed by Comparing the linear movement of plunger 20 relative to 16 with the actual amount of fluid being dispensed For example, in the calibration mode of Pump 1, a syringe filled with liquid is The vessel 14 can be placed on a stand 16 and connected to a pump. The pump 1 can be started and The liquid can be delivered from the syringe 14. The user is prompted to enter the amount, The controller 72 records the position of the plunger 20 within the barrel 18 in terms of the measured amount. This action is repeated according to the instructions on the pump display, These points are used to generate several data points for syringe position and delivery volume for a particular syringe. may be used in a line-fitting calculation to calibrate the controller 72 to operate at The information can be used whenever the particular type of syringe 14 for which it was calibrated is used. The data can be stored in the controller 72 so that the data can be read and written.

[0075] Alternatively, the controller 72 of the pump 1 may advance the plunger 20 into the barrel 18. the syringe may be programmed to prompt the user to perform a series of syringe operations that will The microprocessor 89 records the syringe movement and calibrates the movement with the amount of fluid dispensed. For example, the controller 72 may control the plunger 18 of the syringe 14. Move the meter 20 to the 0 ml mark and then confirm that the action has been taken. The user can be prompted, and the microprocessor 89 then records the measurements. This process can be repeated again at the center of the syringe, where the syringe is filled with another volume. A command to move to a marker (e.g., 30 ml) can then be given. The microprocessor 89 records the distance traveled by the syringe (i.e., barrel 18). Next, the plunger 20 in the syringe 14 is inserted into another volumetric chamber, such as at or near the end of the barrel 18. The microprocessor 89 can provide instructions to move the The distance traveled by the syringe is again recorded. These three data points are used to calculate the A linear curve calibration can be created.

[0076] Thus, various objects and features are achieved by the various embodiments disclosed herein. It will be seen that the pump controller 72 has a delivery time corrector 85. The feed time corrector 85 is configured to allow the microprocessor 89 to operate the rotor 37 to set the feed time. Adjust the length of time that pump 1 is operating in the feed phase by adjusting the length of time that pump 1 delivers feed fluid through port 7. This allows for deviations in the amount of fluid drawn for the syringe 14 and delivered to the subject during use. Thus, the subject is able to obtain a more precise amount of dispensed fluid for a given dispense cycle. You can receive it.

[0077] 22-25, another embodiment of a pump support is generally designated 116. The pump support 116 receives the pump 1 and supports the pump 1 on a horizontal support surface S such as a tabletop. The holder 116 is configured to support the pump 1 therein. The base 122 includes a rear wall 126 and a base 122 defining a socket 124. a bottom wall 128 projecting forward from the bottom wall; and two walls projecting upward from the bottom wall and forward from the rear wall on either side of the rear wall. The rear wall 126 includes a pair of side walls 130. A mount 132 may be disposed on the rear wall 126. In form, the mount 132 has a rounded triangular or arched shape and is generally Mounting flanges 134 extend from the top of the mount to the bottom wall 128 and diverge on either side of the mount. The mounting flange 134 of the mount 132 is fitted into a groove 13 formed on the back of the pump 1. 6 (FIG. 4A) and configured to slide and engage the pump to the support 116. The posts 138 may be located on the rear wall 126 within the perimeter of the mount 132. and a lever for receiving a retainer (not shown) for locking the pump 1 to the base 122. It may have a receptacle.

[0078] The legs 142 pivot on respective mounting arms 144 located on the bottom of the base 122. Each mounting arm 144 is rotatably mounted on a respective one of the opposite ends of the base 122. Each mounting arm 124 extends from the side of the mounting arm 124 generally between the bottom wall 128 and the respective side wall 130. Leg 142 includes an extension portion 146 and a pivot portion 148 at the end of the extension portion. The legs 142 pivot about pivot section 148 of the mounting arm 144. It includes a top surface 150, a flat bottom surface 152, and an end surface 154 connecting the top and bottom surfaces. 142 pivot upward until they engage the corresponding side walls 130, 144. The mounting arms 144 are pivoted downward until they engage the extensions 146 of the mounting arms 144. In one embodiment, each leg 142 is configured to pivot through a range of approximately 180 degrees. However, other turning ranges are also contemplated.

[0079] When the support 116 is supported on a horizontal support surface S, each leg 142 is independently pivotable. and is configured to pivot about an axis defined by pivot portion 148. Thus, the legs 142 pivot toward the support surface to engage the support surface, and at least The support member is configured to pivot away from the support surface to release the other portion from the support surface. For example, one of the legs 142 may be pivoted to expose the bottom surface 1 of the leg (e.g., as shown in FIG. 25). 52 and / or end surface 154 engages support surface S, and supports 116 (and pumps on the supports) 1) Raise or tilt one side above the other to change the angular orientation of the pump. In the case of a pump 1 with a horizontally mounted syringe, this allows the tip Depending on the direction it is pointed and the legs are pivoted to engage the support surface, the tip of the syringe may be If the syringe tip is tilted up, this means Similar function to the pump support 16 with syringes oriented obliquely relative to the horizontal and vertical axes As mentioned above, this orientation has advantages when breast milk is delivered from a syringe. The legs 142 are angled from about 1 degree to the horizontal axis when the holder is positioned on a horizontal support surface. The legs 142 are also configured to tilt the support 116 to an angle between about 40 degrees. Do not orient the syringe attached to pump 1 in any other direction without departing from the range shown. The pump support 116 can also be operated to attach the pump support to a support such as an IV pole. It is configured to be attached to a clamping device (not shown) for attachment to a carrier.

[0080] Embodiments may include programs executed by one or more computers or other devices. It may be described in the general context of computer-executable instructions, such as system modules. Computer-executable instructions perform particular tasks or implement particular abstract data types. including routines, programs, objects, components, and data structures that including, but not limited to, one or more computer-executable components or modules Aspects may include any number and organization of such components or modules. For example, various features or aspects may be implemented in specific computer-executable programs. Instructions or specific components or modules shown in the figures and described herein Not limited to, other embodiments may be used beyond those shown and described herein. may contain different computer-executable instructions or components with more or less functionality. It is possible.

[0081] Also, performance of the operations in any of the embodiments shown and described herein The order of steps or execution is not important unless otherwise specified. Unless otherwise specified, the operations may be performed in any order and the embodiments may be implemented in any order other than as disclosed herein. For example, an action may be performed before another action or at the same time. Performing or executing a particular action before or after the execution of a particular action is considered within the scope of one or more aspects. can be obtained.

[0082] In operation, the microprocessor 89 of the controller 72 performs the functions disclosed herein. To implement one or more aspects of the present invention, computer-executable instructions such as those shown in the figures may be used. Any of the various aspects may be performed by remote processing linked via a communications network. It may be practiced in a distributed computing environment where tasks are performed by devices. In a distributed computing environment, program modules may be found in memory storage devices The computer may be located on both local and remote computer storage media, including:

[0083] When introducing elements of the invention or preferred embodiments thereof, the articles "a," "an," "t" and "t" are used. "He" and "said" are used to mean that there is one or more elements. The terms "comprise," "include," and "have" are intended to be inclusive. The illustration means that there may be additional elements other than those listed.

[0084] In view of the above, it will be seen that the several objects of the invention are achieved and other advantageous results attained. You will understand that.

[0085] Various modifications may be made to the above structure without departing from the scope of the present invention. All matter contained in the above description or shown in the accompanying drawings is intended to be illustrative and not limiting. , are intended to be construed as illustrative.

[0086] Other Aspects of the Disclosure

[0087] A1. A rotor for rotating around the pump shaft and a rod for engaging with the pump set. and at least one roller attached to the rotor. 1. A pump set for use with a control device, comprising:

[0088] A pump system of a flow control device is engaged to pump fluid through the tubing. a tube configured as

[0089] a syringe assembly connected to a tube, the syringe and the syringe being held in a generally vertical position; and a stand configured to support the syringe, the syringe supported by the stand being When the syringe is supported on the stand, the outlet of the syringe in fluid communication with the tube faces generally upward. a syringe assembly oriented so as to A pump set comprising:

[0090] A2. The stand is configured to hold the plunger in place relative to the stand. A pump set as described in A1.

[0091] A3. The stand has a base and a guide wall protruding upward from the base. The base is A pump set as described in A2, which is formed to capture the end of the plunger.

[0092] A4. The stand supports a gripper mounted to move along a guide wall. A gripper configured to hold the syringe barrel around the base of the stand A pump set as described in A3.

[0093] A5. The base is configured to rest on a support surface, the guide wall extends upwardly from the support surface, and the injection A pump set as described in A2 or A3, wherein the vessel extends upward from the base.

[0094] B1. A syringe assembly for use with a flow control device, the syringe assembly comprising:

[0095] A syringe for holding a quantity of a supply fluid, a barrel and a moving element within the barrel to draw fluid into the barrel and push fluid out of the barrel a syringe having a disposable plunger;

[0096] a stand comprising a support configured to support the syringe in a dispensing position;

[0097] Mounted on a stand, indicating that the supply fluid is delivered from a barrel, a position sensor configured to detect movement of the syringe barrel; A syringe assembly comprising:

[0098] B2. Position sensors include potentiometers, cameras, magnetic foil sensors, and non-magnetic inductive sensors. The syringe assembly of B1 including one of the sensors.

[0099] B3. The stand includes a gripper configured to connect to the barrel of the syringe, A syringe assembly according to any one of B1 to B2, wherein the nozzle is movable relative to the stand.

[0100] B4. The syringe assembly of B3, wherein the gripper is connected to a position sensor.

[0101] B5. The position sensor includes a camera and the syringe assembly is mounted on a stand. The method of claim 1, further comprising: Projectile assembly.

[0102] C1. A pump set for delivering fluid from a source through the pump set to a subject; A flow control device to be used together,

[0103] A pump set is acted upon to generate fluid flow within the pump set during a delivery cycle. a pump device capable of

[0104] Controlling the operation of a pumping device in a supply arrangement for producing fluid flow within a pump set a controller in communication with the pump device to control the pump device, the controller including a processor and and a memory, the controller storing the selected flow rate and the desired volume of fluid in the memory. The controller is adapted to store the actual flow rate from the source from the selected flow rate. To take into account any detected deviations in the volume of fluid through the pump set during the delivery cycle A supply time corrector is provided to process the supply time for operating the pump device to deliver the Controllers configured to run within the A flow control device comprising:

[0105] C2. The controller compensates for detected deviations of the actual flow rate from the selected flow rate. The flow control device according to C1, wherein the operation of the pump device is temporarily suspended in order to

[0106] C3. The controller compares the total amount of fluid actually delivered with the desired amount of fluid and and terminating the delivery cycle when the difference between the flow rates is within a predetermined threshold. Equipment.

[0107] C4. The supply time corrector was corrected based on the formula X = (Y + Yl) / (Z + Zn) Calculate the delivery time, where X is the selected flow rate for the fluid and Y is the time during the delivery cycle. Yl is the amount of fluid already delivered from the source since the last correction calculation. where Z is the amount of dispensed fluid, Z is the total time elapsed during the dispense cycle, and Zn is the amount of dispensed fluid. The flow rate control device according to any one of C1 to C3, which is an adjustment of a supply time.

[0108] C5. The controller will initiate the dispense time correction only after a threshold amount of fluid has been dispensed from the source. The flow control device according to any one of C1 to C4, which is programmed to execute the .

[0109] D1. The flow controller acts on a pump set attached to a flow control device to control the flow through the pump set. A pumping device of a flow control device is used to generate a flow of the fluid from the barrel and the fluid received within the barrel. 1. A method of delivering a fluid from a syringe having a plunger, comprising:

[0110] The controller of the pump device is configured to determine the selected flow rate and the amount of fluid delivered from the syringe during the operating cycle. inputting at least one of the total amounts of fluids to be

[0111] Initiating operation of the pumping device using the controller to draw fluid from the syringe. And,

[0112] The relative movement between the plunger and the syringe is detected, and a signal representing the detected relative movement is output to the controller. sending it to Laura;

[0113] Computer executable instructions in the controller are used to determine when the fluid is actually delivered from the syringe. the pumping device during the operating cycle to compensate for deviations in the speed and selected flow rate calculating a corrected delivery time for operating the pump set to deliver fluid through the pump set;

[0114] Activating a flow control device to deliver fluid through a pump set at a corrected delivery time Koto and A method comprising:

[0115] D2. The controller delays the start of pumping device operation by the calculated compensation delivery time. The method according to D1.

[0116] D3. When the relative movement between the plunger and syringe is detected, the controller activates the pump device. The method according to D1 or D2, wherein the operation of

[0117] D4. Upon detecting relative movement between the plunger and syringe that exceeds a predetermined threshold of movement, The method according to D3, wherein the controller stops operation of the pump device.

[0118] D5. Corrected delivery time is the time at which the pumping device operates to pump fluid through the pump set. The method according to any one of D1 to D4, wherein the calculation is performed when the device is not being operated.

[0119] E1. A method of delivering breast milk to an infant, comprising:

[0120] Recovering breast milk stored in a syringe having a barrel and a plunger received within the barrel To do,

[0121] The syringe is positioned so that its longitudinal axis is generally vertical and the syringe outlet is at the top. and attaching it to a stand.

[0122] Delivering breast milk from a syringe to an infant while on the stand A method comprising:

[0123] E2. Milk is delivered from a syringe by applying vacuum pressure to the syringe outlet. The method of E1, comprising withdrawing breast milk from the breast.

[0124] E3. To deliver breast milk, hold the syringe barrel against the stand and plunger. The method according to A1 or E2, comprising moving.

[0125] F1. How to calibrate a flow control device used to deliver fluid from a syringe to a subject It is a law,

[0126] Display a command on the flow controller display to check the comparison results stored by the flow controller. starting a normal routine;

[0127] storing an initial position of the syringe plunger relative to the syringe barrel;

[0128] Delivering a first amount of fluid from a syringe;

[0129] urging the delivered first quantity of fluid into the flow control device;

[0130] storing a second position of the plunger; and

[0131] activating the flow control device to deliver a second amount of fluid;

[0132] urging the delivered second amount of fluid into the flow control device;

[0133] storing a third position of the plunger; and

[0134] Within the flow control device, the movement of the plunger relative to the syringe barrel and the amount of fluid delivered Identifying the movement / volume relationship between

[0135] storing the displacement / volume relationship in a memory of the flow control device;

[0136] storing a syringe identifier for the syringe so that the flow control device can subsequently The transfer / volume relationship can be invoked to use a syringe in the delivery of A method comprising:

[0137] G1. How to calibrate a flow control device used to deliver fluid from a syringe to a subject It is a law,

[0138] Display a command on the flow controller display to check the comparison results stored by the flow controller. starting a normal routine;

[0139] The flow control device stores the initial position of the syringe plunger relative to the syringe barrel. And,

[0140] Moving the plunger relative to the barrel to a second position at the first known volume marker and displaying instructions to

[0141] The movement of the plunger relative to the barrel from the initial position to the second position is recorded on the flow control device. And,

[0142] Move the plunger relative to the barrel to a third position at a second known volume marker. and to display instructions such as

[0143] The movement of the plunger relative to the barrel from the second position to the third position is recorded on the flow control device. To do,

[0144] Within the flow control device, the movement of the plunger relative to the syringe barrel and the amount of fluid delivered Identifying the movement / volume relationship between

[0145] The movement / volume relationship is stored in the memory of the flow control device. A method comprising:

[0146] G2. Further comprising storing a syringe identifier for the syringe, thereby controlling the flow control device. The placement can invoke a displacement / volume relationship for use with syringes in subsequent fluid delivery, The method described in G1.

[0147] H1. The flow controller acts on a pump set attached to a pump set to control the flow of A pumping device of a flow control device is used to generate a flow of the fluid from the barrel and the fluid received within the barrel. 1. A method of delivering a fluid from a syringe having a plunger, comprising:

[0148] The controller of the pump device is configured to determine the selected flow rate and the amount of fluid delivered from the syringe during the operating cycle. inputting at least one of the total amounts of fluids to be

[0149] Initiating operation of the pumping device using the controller to draw fluid from the syringe. And,

[0150] The relative movement between the plunger and the syringe is detected, and a signal representing the detected relative movement is output to the controller. sending it to Laura;

[0151] deactivating the pumping device to limit the vacuum pressure in the syringe;

[0152] Restarting the pumping device A method comprising:

[0153] I1. A pump set for delivering fluid from a source through the pump set to a subject; A flow control device to be used together,

[0154] A pump set is acted upon to generate fluid flow within the pump set during a delivery cycle. a pump device capable of

[0155] Controlling the operation of a pumping device in a supply arrangement for producing fluid flow within a pump set a controller in communication with the pump device to control the pump device, the controller including a processor and and a memory, the controller storing the selected flow rate and the desired volume of fluid in the memory. The controller is adapted to limit the vacuum pressure delivered to the source. a controller configured to operate the pump device; A flow control device comprising:

[0156] J1. A pump set and a pump for delivering fluid from a source through the pump set to a subject. A flow control device used together,

[0157] A pump set is acted upon to generate fluid flow within the pump set during a delivery cycle. a pump device capable of

[0158] Controlling the operation of a pumping device in a supply arrangement for producing fluid flow within a pump set a controller in communication with the pumping device for controlling a predetermined amount of dispensed solution from the source; a controller configured to stop operation of the pumping device when delivery of the fluid is detected; A flow control device comprising:

[0159] J2. The source is a syringe including a barrel and a plunger received within the barrel. The controller stops the pumping device when a predetermined movement of the plunger is detected. , A flow control device according to J1.

[0160] K1. An enteral nutrition system for delivering fluids to a subject, comprising:

[0161] a feeding set assembly including a cassette and a tube attached to the cassette;

[0162] a syringe connected to the tube; and a stand configured to support the syringe. A syringe assembly, the stand including a base for supporting the stand on a horizontal support surface. and a holder for fixing the syringe to the stand, the holder being attached to the base. and can be rotated relative to the base to orient the syringe in at least two different positions. a selectively positionable syringe assembly;

[0163] The tubing is configured to draw fluid from the syringe to create a fluid flow within the delivery set. a flow control device including a pump device that can be used An enteral nutrition system comprising:

[0164] L1. A supply set assembly for use with a flow control device comprising:

[0165] A cassette configured to be removably attached to a flow control device, a cassette including a port;

[0166] a tube connected to the inlet port;

[0167] A valve assembly connected to a tube, the valve housing and the ambient air being The closed position prevents ambient air from entering the tube and the closed position prevents ambient air from entering the tube and exiting the tube. and a valve actuable between an open position to allow fluid to be removed. Yellowtail and A supply set assembly comprising:

[0168] M1. A method for delivering a reinforcer to a subject from a syringe using a pump device with a flow control device. There was,

[0169] A quantity of fortifier containing the total amount of desirable nutrients and a quantity of undesirable nutrients is dispensed into a syringe. and

[0170] attaching a syringe to a flow control device;

[0171] orienting the syringe generally vertically with the syringe outlet pointing downward;

[0172] commencing operation of a pumping device to draw fortifying agent from the syringe;

[0173] The syringe is then delivered to the subject so that the preferred nutrients in the fortifier are preferentially delivered from the syringe. delivering at least a portion of the amount of the enhancer; A method comprising:

Claims

1. A method for operating a flow control device for delivering fluid from a syringe, The flow rate control device comprises a pumping device and a controller including a processor and memory. The flow control device is positioned on the support surface, The syringe contains a certain amount of breast milk, including the total amount of fat. The syringe is attached to the flow control device such that the outlet of the syringe faces upward. The aforementioned method, The controller initiates the operation of the pumping device to draw the fluid from the syringe over a set period of time, and the pumping device delivers at least a portion of the set amount of breast milk from the syringe such that at least 10% of the total amount of fat in the breast milk is delivered from the syringe within the first third of the set period of time during which the pumping device operates to draw the breast milk from the syringe. A method that includes this.

2. The method according to claim 1, wherein at least 30% of the total amount of fat in the breast milk is delivered from the syringe within the first third of the constant time in which the pumping device operates to draw the breast milk from the syringe.

3. The method according to claim 1, wherein at least 44% of the total amount of fat in the breast milk is delivered from the syringe within the first third of the constant time in which the pumping device operates to draw the breast milk from the syringe, and the syringe is oriented substantially perpendicular to the support surface.

4. The method according to claim 3, wherein the constant time for which the pumping device operates is 60 minutes.

5. The method according to claim 1, wherein at least 60% of the total amount of fat in the breast milk is delivered from the syringe within the first half of the constant time in which the pumping device operates to draw the breast milk from the syringe.

6. The method according to claim 5, wherein the syringe is oriented substantially perpendicular to the support surface.

7. The method according to claim 5, wherein at least 65% of the total amount of fat in the breast milk is delivered from the syringe within the first two-thirds of the constant time in which the pumping device operates to draw the breast milk from the syringe.

8. The method according to claim 7, wherein at least 80% of the total amount of fat in the breast milk is delivered from the syringe within the first five-sixths of the constant time in which the pumping device operates to draw the breast milk from the syringe.

9. The method according to claim 8, wherein the syringe is oriented at an angle of at least 40 degrees with respect to the support surface.

10. The method according to claim 1, wherein at least 50% of the total amount of fat in the breast milk is delivered from the syringe within the first half of the constant time in which the pumping device operates to draw the breast milk from the syringe.

11. The method according to claim 10, wherein the syringe is oriented at an angle of at least 25 degrees with respect to the support surface.

12. The method according to claim 1, wherein at least 60% of the total amount of fat in the breast milk is delivered from the syringe within the first two-thirds of the constant time in which the pumping device operates to draw the breast milk from the syringe.

13. The method according to claim 12, wherein the syringe is oriented at an angle of at least 25 degrees with respect to the support surface.

14. The method according to claim 1, wherein the outlet of the syringe is located in the center of the barrel of the syringe.

15. The method according to claim 1, wherein the syringe is oriented substantially perpendicular to the support surface.

16. The method according to claim 1, wherein the syringe is oriented at an angle of at least 25 degrees with respect to the support surface.

17. The method according to claim 1, wherein delivering at least a portion of a certain amount of breast milk includes drawing breast milk out of the syringe by applying vacuum pressure to the outlet of the syringe using the flow rate control device.

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