Aspheric phase ring structured lens design, its manufacture and use

Abstract

Described herein are ophthalmic lenses, such as extended depth of focus (EDOF) ophthalmic lenses and multifocal lenses, having bilateral aspheric optics including phase ring structures. Refraction of light passing through one or more regions of the phase ring structures described herein can produce constructive interference, thereby producing extended depth of focus, as well as improved far, intermediate and near foci, either individually or as a set. The ophthalmic lenses described herein can provide improved vision and enhanced contrast, and reduce or eliminate visual effects such as dysphotopsia (e.g., halos and glare). TIFF2025501395000056.tif49170

Description

[Technical field]

[0001] This application claims the benefit of priority under 35 USC §119(e) to U.S. patent application Ser. No. 63 / 299,635, filed Jan. 14, 2022, the contents of which are incorporated by reference herein in their entirety.

[0002] Field The present disclosure relates generally to ophthalmic lenses, and more particularly to novel double-sided aspheric phase-ring structured lenses, their design, their manufacture and their use. [Background technology]

[0003] background Ophthalmology is the branch of medicine concerned with the anatomy, physiology and diseases of the human eye. The anatomy of the human eye is quite complex. The main structures of the eye include the cornea, a non-spherical transparent tissue on the outer front surface of the eye; the iris, the colored part of the eye; the pupil, an adaptive opening in the iris that regulates the amount of light entering the eye; the lens, a small transparent disc within the eye that focuses light rays onto the retina; and the retina, a layer that forms the back or rear side of the eye and converts sensed light into electrical impulses that are transmitted through the optic nerve to the brain. The posterior chamber (i.e., the space between the retina and the lens) is filled with aqueous humor, and the anterior chamber (i.e., the space between the lens and the cornea) is filled with vitreous humor, a clear, jelly-like substance.

[0004] The natural crystalline lens has a flexible, transparent, biconvex structure that works with the cornea to refract light and focus it on the retina. The crystalline lens is flatter at its front than its back, and its curvature is controlled by the ciliary muscle, to which it is attached by a suspensory ligament called the zonules. Changing the curvature of the crystalline lens changes the focal length of the eye to focus on objects at different distances. To see objects closer to the eye, the ciliary muscle contracts and the crystalline lens thickens, resulting in a rounder shape and therefore higher refractive power. To change focus to objects that are more distant, the crystalline lens must relax, thus increasing its focal length. This process of changing curvature and adapting the focal length of the eye to form a sharp image of the object on the retina is called accommodation.

[0005] In humans, the refractive power of the crystalline lens in its natural environment is about 18-20 diopters, roughly one-third of the total refractive power of the eye. The cornea provides the remaining 40 diopters of total refractive power.

[0006] As the eye ages, the lens becomes increasingly cloudy (called a cataract). Some diseases such as diabetes, trauma, some medications, and excessive exposure to UV rays can also cause cataracts. Cataracts are painless but cause cloudy, blurred vision. Treatment for cataracts involves surgery, during which the cloudy lens is removed and replaced with an artificial lens, commonly called an intraocular lens (IOL).

[0007] Another age-related effect is called presbyopia, which is manifested by difficulty reading small print or seeing nearby images as clearly. Presbyopia is generally thought to be caused by the lens inside the eye thickening and losing its flexibility. Age-related changes also occur in the ciliary muscle that surrounds the lens. As it becomes less elastic, it becomes more difficult for the eye to focus on objects that are close to it.

[0008] A variety of intraocular lenses are also used to correct other visual disorders such as myopia, i.e., nearsightedness, an inability to see distant objects, caused, for example, by a cornea with too great a curvature. The effect of myopia is that distant light rays are not focused exactly on the surface of the retina, but at a point in front of the retina. Hyperopia, or farsightedness, caused by an abnormally flat cornea, focuses light rays entering the eye behind the retina, preventing the eye from seeing nearby objects. Astigmatism is another common cause of visual disorders in which an irregularly shaped cornea causes blurred images.

[0009] In most cases, during cataract surgery, an intraocular lens (IOL) is implanted in the patient's eye to replace the crystalline lens and compensate for the loss of refractive power of the removed crystalline lens. Modern IOL optics are designed to have multifocal optics (multifocal IOLs, more specifically also called trifocal lenses) to provide near, intermediate and far vision of objects. Presbyopia is traditionally corrected with glasses or contact lenses, but patients can also opt for multifocal optics. In some cases, IOLs include diffractive structures to have not only far-focus refractive power but also near-focus refractive power, thereby providing some degree of pseudo-accommodation. However, various aberrations, such as spherical and astigmatism aberrations, can adversely affect the optical performance of such lenses. For example, spherical aberration can reduce visual contrast, especially with large pupil sizes.

[0010] Multifocal ophthalmic lenses often provide improved quality of vision for many patients, but further improvements would be beneficial. For example, some pseudophakic patients experience undesirable visual effects (dysphotopsia), such as glare or halos, especially when used in dark environments (such as at night). Halos can occur when light from an unused focal point creates a non-focused image that is superimposed on the active focal point. For example, when light from a distant point source is imaged onto the retina by the far focus of a bifocal IOL, at the same time, the near focus of the IOL superimposes a non-focused image on the image formed by the far focus. This non-focused image can appear in the form of a ring of light surrounding the focal image and is called a halo. Another area requiring improvement revolves around the general bifocal nature of multifocal lenses. More specifically, because multifocal ophthalmic lenses generally provide near and far vision, intermediate vision may be impaired.

[0011] Therefore, there is a need for one or more ophthalmic lenses with extended depth of focus (EDOF) that simultaneously provide near, intermediate and far foci and also address the aforementioned adverse effects such as dysphotopsia (e.g., halos, glare, etc.), thereby providing enhanced contrast and improved visual acuity. Summary of the Invention

[0012] overview The present disclosure relates to a bilateral aspheric ophthalmic lens having a phase ring structure that can provide an extended depth of focus, thereby enhancing contrast, improving visual acuity, and reducing undesirable visual effects such as glare and halos. The phase ring structure of the ophthalmic lens described herein can be designed to provide the depth of focus using constructive phasing through non-diffracting beam principles, thereby maximizing the focal energy in the lens.

[0013] In some embodiments, an ophthalmic lens is provided comprising a lens body, the lens body comprising: a first aspheric surface; and a second aspheric surface comprising a base curvature and a phase ring structure, the phase ring structure comprising an inner region and an outer region, the inner region comprising a first phase ring surface having a first curvature; the outer region comprising a second phase ring surface having a second curvature; an outer edge of the inner region adjacent an inner edge of the outer region, and refraction of light passing through the inner region and the outer region produces constructive interference that produces a far focus and an extended focus.

[0014] In some embodiments, a method of treating an ophthalmic disease or disorder in a subject is provided, comprising: implanting an ophthalmic lens comprising a lens body into an eye of the subject, the lens body comprising: a first aspheric surface; and a second aspheric surface comprising a base curvature and a phase ring structure, the phase ring structure comprising an inner region and an outer region, the inner region comprising a first phase ring surface having a first curvature; the outer region comprising a second phase ring surface having a second curvature; an outer edge of the inner region adjacent an inner edge of the outer region, and refraction of light passing through the inner region and the outer region produces constructive interference that generates a far focus and an extended focus.

[0015] In some embodiments, a method of manufacturing an ophthalmic lens is provided, comprising: fabricating a first aspheric surface; fabricating a second aspheric surface comprising a base curvature; and generating a phase ring structure on the second aspheric surface, wherein the phase ring structure comprises an inner region and an outer region, the inner region comprising a first phase ring surface having a first curvature; the outer region comprising a second phase ring surface having a second curvature; an outer edge of the inner region adjacent an inner edge of the outer region, and refraction of light passing through the inner region and the outer region produces constructive interference that produces a far focus and an extended focus.

[0016] In some embodiments, an ophthalmic lens is provided comprising a lens body, the lens body comprising: a first aspheric surface; and a second aspheric surface comprising a base curvature and a phase ring structure, the phase ring structure comprising an inner region, an intermediate region, and an outer region, the inner region comprising a first phase ring surface having a first curvature; the intermediate region comprising a second phase ring surface having a second curvature; the outer region comprising a third phase ring surface having a third curvature; an outer edge of the inner region adjacent an inner edge of the intermediate region; and an outer edge of the intermediate region adjacent an inner edge of the outer region, wherein refraction of light passing through the inner region, the intermediate region, and the outer region creates constructive interference that produces a near focus and a far focus.

[0017] In some embodiments, a method of treating an ophthalmic disease or disorder in a subject is provided, comprising: implanting an ophthalmic lens comprising a lens body into an eye of the subject, the lens body comprising: a first aspheric surface; and a second aspheric surface comprising a base curvature and a phase ring structure, the phase ring structure comprising an inner region, an intermediate region, and an outer region, the inner region comprising a first phase ring surface having a first curvature; the intermediate region comprising a second phase ring surface having a second curvature; the outer region comprising a third phase ring surface having a third curvature; an outer edge of the inner region adjacent an inner edge of the intermediate region; and an outer edge of the intermediate region adjacent an inner edge of the outer region, wherein refraction of light passing through the inner region, the intermediate region, and the outer region creates constructive interference that generates a near focus and a far focus.

[0018] In some embodiments, a method of manufacturing an ophthalmic lens is provided, comprising: fabricating a first aspheric surface; fabricating a second aspheric surface comprising a base curvature; and generating a phase ring structure on the second aspheric surface, wherein the phase ring structure comprises an inner region, an intermediate region, and an outer region, wherein the inner region comprises a first phase ring surface having a first curvature; the intermediate region comprises a second phase ring surface having a second curvature; the outer region comprises a third phase ring surface having a third curvature; an outer edge of the inner region is adjacent to an inner edge of the intermediate region; and an outer edge of the intermediate region is adjacent to an inner edge of the outer region, and wherein refraction of light passing through the inner region, the intermediate region, and the outer region creates constructive interference that generates a near focus and a far focus.

[0019] In some embodiments, a first ophthalmic lens comprising a first lens body, the first lens body comprising a first aspheric surface; and a second aspheric surface comprising a first base curvature and a first optical phase ring structure, the first optical phase ring structure comprising a first inner region and a first outer region, the first inner region comprising a first phase ring surface; and the outer region comprising a second phase ring surface; and a second ophthalmic lens comprising a second lens body, the second lens body comprising a third aspheric surface; and a fourth aspheric surface comprising a second base curvature and a second optical phase ring structure. and a second ophthalmic lens, wherein the second optical phase ring structure comprises a second inner region, an intermediate region, and a second outer region, the second inner region comprising a third phase ring surface; the intermediate region comprising a fourth phase ring surface; and the second outer region comprising a fifth phase ring surface, wherein refraction of light passing through the first inner region and the outer region of the first ophthalmic lens creates a first constructive interference, and refraction of light passing through the second inner region, the intermediate region, and the second outer region creates a second constructive interference, thereby collectively generating a near focus, a far focus, and an extended focus. [Brief description of the drawings]

[0020] The present application can be best understood by reference to the following detailed description taken in conjunction with the accompanying drawings included herein.

[0021] [Figure 1] 1 illustrates a height profile of an aspheric base structure of a double-sided aspheric ophthalmic lens with a phase ring structure, according to some aspects of the present disclosure. [Figure 2A] 1 illustrates a phase profile of a phase ring structure of an Extended Depth of Focus (EDOF) ophthalmic lens according to a first embodiment of the present disclosure. [Figure 2B] 1 illustrates a phase profile of a phase ring structure of an EDOF ophthalmic lens according to a second embodiment of the present disclosure. [Figure 2C] 13 illustrates a phase profile of a phase ring structure of an EDOF ophthalmic lens according to a third embodiment of the present disclosure. [Diagram 3] 1 illustrates a full height profile of an aspheric surface with a phase ring structure of an EDOF ophthalmic lens according to some embodiments of the present disclosure. [Figure 4] 1 shows the optical performance (Modulation Transfer Function, MTF) of an EDOF ophthalmic lens according to a first embodiment of the present disclosure. [Diagram 5] 4 shows the optical performance (MTF) of an EDOF ophthalmic lens according to a second embodiment of the present disclosure. [Figure 6] 4 shows the optical performance (MTF) of an EDOF ophthalmic lens according to a third embodiment of the present disclosure. [Figure 7] 4 shows the optical performance (MTF) of an EDOF ophthalmic lens according to the fourth embodiment of the present disclosure. [Figure 8] 1 shows the optical performance (MTF) of an EDOF ophthalmic lens according to a fifth embodiment of the present disclosure. [Figure 9] 1 shows the optical performance (MTF) of an EDOF ophthalmic lens according to a sixth embodiment of the present disclosure. [Figure 10] 13 shows the optical performance (MTF) of an EDOF ophthalmic lens according to the seventh embodiment of the present disclosure. [Figure 11] 1 shows a flow chart illustrating the design and manufacture of a double-aspheric ophthalmic lens with a phase ring structure according to some aspects of the present disclosure. [Figure 12-1]12A and 12B show a plan view and a detailed view of an EDOF ophthalmic lens, respectively, according to some embodiments of the present disclosure. [Figure 12-2] 12C and 12D show cross-sectional views of an EDOF ophthalmic lens and a lens body of the EDOF ophthalmic lens, respectively, according to some embodiments of the present disclosure. [Figure 13A] 1 illustrates a phase profile of a phase ring structure of a multifocal ophthalmic lens according to a first aspect of the present disclosure. [Figure 13B] 3 shows a phase profile of a phase ring structure of a multifocal ophthalmic lens according to a second aspect of the present disclosure. [Figure 14] 1 illustrates a full height profile of an aspheric surface with a phase ring structure of a multifocal ophthalmic lens according to some aspects of the present disclosure. [Figure 15A] 1 shows the optical performance (modulation transfer function, MTF) of a multifocal ophthalmic lens according to a first embodiment of the present disclosure. [Figure 15B] 4 shows the optical performance (MTF) of a multifocal ophthalmic lens according to a second embodiment of the present disclosure. [Figure 15C] 4 shows the optical performance (MTF) of a multifocal ophthalmic lens according to a third embodiment of the present disclosure. [Figure 16-1] 16A and 16B show a plan view and a detailed view of a multifocal ophthalmic lens, respectively, according to some embodiments of the present disclosure. [Figure 16-2] 16C and 16D show cross-sectional views of a lens body of a multifocal ophthalmic lens according to some embodiments of the present disclosure. DETAILED DESCRIPTION OF THE PREFERRED EMBODIMENTS

[0022] Detailed Description The present disclosure relates to bilaterally aspheric ophthalmic lenses with phase ring structures, such as extended depth of focus (EDOF) lenses and multifocal lenses, and methods of designing and manufacturing such lenses. The lenses may include a first aspheric surface (anterior surface) and a second aspheric surface (posterior surface). One of the two surfaces may include a phase ring structure, while the other surface may optionally include a toric component. The phase ring structure may include a series of concentric circular regions extending from the center of the lens to the edge of the lens. The transitions between the regions in the phase ring structure may be represented by rings that correspond to the ridges in the surface profile of the ophthalmic lens. The phase ring structure is designed to provide depth of focus using constructive phase matching to maximize the focal energy, according to non-diffracting beam principles. The multifocal and extended depth of focus lenses described herein may utilize refractive optics, where the surface profile of the phase ring structure includes slanted walls, rather than the vertical walls (or steps) associated with, for example, diffractive lens designs. Refractive lenses provide focus using the refraction effect of light waves at refractive surfaces that include interfaces with different refractive indices. Thus, when light refracts through one or more regions of the lenses described herein, constructive interference results in an extended depth of focus and improved far, intermediate and near foci.

[0023] A bilateral aspheric design produces an improved modulation transfer function (MTF) of the lens-eye combination due to reduced aberrations and enhanced visual contrast compared to a single aspheric lens. The phase ring structures described herein allow for an extended depth of focus for ophthalmic lenses, which may produce continuous vision from near, intermediate and far foci as a set of lenses. Various phase ring structures are described in more detail below with reference to two bilateral aspheric lens designs, hereafter referred to as Extended Depth of Focus (EDOF) lenses and multifocal lenses.

[0024] 1 illustrates an aspheric base curvature height profile as a function of radial distance from the center of an ophthalmic lens according to some embodiments of the present disclosure. The aspheric base curvature in FIG. 1 is based on the following parameters, which correspond to the height profile equation provided in Equation (V) (discussed in more detail below): c is the curvature, k is the conic constant, and A is the radius of curvature of the aspheric base. i (i is 4, 6, 8, etc.) are higher order aspheric coefficients). The height profile shown in Figure 1 may be applied to each of the lens designs described herein (e.g., extended depth of focus lenses and multifocal lenses). The remaining figures provided herein may be described with respect to the specific lens designs shown accordingly.

[0025] Extended Depth of Focus (EDOF) Ophthalmic Lenses In some embodiments, a double-sided aspheric multifocal lens design with a phase ring structure may be provided to extend the depth of focus at least between an intermediate focus and a far focus. Figures 2A-2C show various phase profiles of a phase ring structure of an extended depth of focus (EDOF) ophthalmic lens according to some embodiments of the present disclosure. The phase profile of the phase ring structure may correspond to the full height profile of the phase ring structure, as described below in connection with the height profile formula provided by formula (II). As described above, the phase ring structure of the lenses provided herein may include a series of concentric regions, such as two, three, four or more regions. Figures 2A-2C show the respective regions based on radius in the corresponding phase profile diagrams.

[0026] For example, FIG. 2A shows the inner radius (r in ) and the outer radius (r out), with the inner radius extending from the optical axis of the lens to the outer edge of the inner region of the phase ring structure, and the outer radius extending from the optical axis to the outer edge of the outer region of the phase ring structure. The phase profile provided in FIG. 2A may correspond to at least Modulation Transfer Function (MTF) examples 1-3 shown in FIGS. 4-6, respectively, each of which is described in further detail below with reference to examples provided herein. The phase ring structure shown in FIG. 2A may have a real add power that is 2.4D, where the real add power is the difference between the add power at the far focus and the add power at the extended focus. The actual add power of a lens having a phase ring structure corresponding to the phase profile of FIG. 2A is expressed as the theoretical add power of a lens without the phase ring structure. TIFF2025501395000004.tif8128. For example, the theoretical add power of a lens without a phase ring structure corresponding to the phase profile of FIG. 2A may be 7.2D, which can be determined using the following formula (III). As described above, the phase ring structure can be designed to provide focal depth and maximize focal energy using constructive phase matching through the non-diffractive beam principle. Thus, when light passing through the lens is refracted while passing through the inner and outer regions, constructive interference caused by refraction from different regions of the EDOF lens can generate far and extended foci.

[0027] In some embodiments, the inner region of the phase ring structure may include a first phase ring surface having a first curvature. The curvatures described herein may include one or more continuous arcs, parabolas, and / or lines. As illustrated, the first curvature may be monotonically decreasing (e.g., negatively sloped) as it extends outward from the optical axis of the lens. The first curvature may include a first (inner) sloped portion sloped at a first angle relative to the optical axis of the ophthalmic lens and a second (outer) sloped portion sloped at a second angle relative to the optical axis, each of the first and second sloped portions both being monotonically sloped relative to the optical axis. The first angle may be greater than the second angle such that the slope of the inner sloped portion is less than the slope of the outer sloped portion. The inner radius (r in ) may be greater than 0 mm and less than or equal to 5 mm, for example, 0.30 mm, 0.35 mm, 0.40 mm, 0.45 mm, 0.55 mm, 0.60 mm, 0.65 mm, or 0.70 mm.

[0028] In some embodiments, the outer region of the phase ring structure may include a second phase ring surface having a second curvature. The second curvature may include a first (inner) sloping portion sloping at a third angle relative to the optical axis of the ophthalmic lens, a second (middle) sloping portion sloping at a fourth angle relative to the optical axis, and a third (outer) sloping portion sloping at a fifth angle relative to the optical axis. As shown, the second curvature may not monotonically increase or decrease in a direction outward from the optical axis of the lens. Rather, the middle sloping portion and the second outer sloping portion may both be monotonically sloping (e.g., both negatively sloping) relative to the optical axis, and the second inner sloping portion may be sloping in a direction opposite to that of the middle sloping portion and the second outer sloping portion, such that the second curvature as a whole is non-monotonic. The fourth angle may be greater than the fifth angle, such that the slope of the middle sloping portion is less than the slope of the outer sloping portion. The outer radius (r out) may be greater than 0 mm and less than or equal to 5 mm, for example, 0.70 mm, 0.75 mm, 0.80 mm, 0.85 mm, 0.90 mm, 0.95 mm, 1.00 mm, 1.05 mm, 1.10 mm, 1.15 mm, 1.20 mm, 1.25 mm, or 1.30 mm. The outer radius of the phase profile of the phase ring structure may be proportional to the inner radius. For example, the relationship between the inner radius and the outer radius is 1≦r out / r in It can be expressed as ≦3.

[0029] In some embodiments, the outer edge of the inner region of the phase ring structure may be adjacent to the inner edge of the outer region of the phase ring structure. As shown in FIG. 2A, the transition between the first curvature and the second curvature may include a minimum in the phase profile because the slope direction (negative) of the outer slope portion of the first curvature may be opposite to the slope direction (positive) of the inner slope portion of the second curvature. Similarly, the second phase ring surface may include a maximum in the phase profile because the slope direction (positive) of the inner slope portion of the second curvature may be opposite to the slope direction (negative) of the middle slope portion. The minimum and maximum may correspond to the position of the ring in the phase ring structure. The region between the minimum and maximum may be referred to as the transition region between two rings in some embodiments. In some embodiments, one or more rings in the phase ring structure may be located between the rings corresponding to the minimum and / or maximum. Thus, the minima and maxima in the phase profile may impart a raised design in the profile of the lens surface profile, whereby at least the raised portions in the surface profile may correspond to rings in the phase ring structure.

[0030] 2B illustrates a phase profile of a phase ring structure of an EDOF ophthalmic lens according to some embodiments of the present disclosure. The phase profile illustrated in FIG. 2B may include one or more features of the phase profile described above with respect to FIG. 2A. For example, a ring structure corresponding to the phase profile illustrated in FIG. 2B may include an inner region and an outer region, whereby the inner radius (r in) may extend from the optical axis of the lens to the outer edge of the inner region of the phase ring structure, and the outer radius (r out ) may extend from the optical axis to an outer edge of the outer region of the phase ring structure. The inner region may include a first phase ring surface having a first curvature and the outer region may include a second phase ring surface having a second curvature. The phase profile provided in FIG. 2B may correspond to at least Modulation Transfer Function (MTF) examples 6-7 shown in FIGS. 9-10, respectively, each of which is described in more detail below. The phase ring structure shown in FIG. 2B has an effective add power of 3.0D. TIFF2025501395000005.tif8128. The theoretical add power of a lens without the phase ring structure corresponding to the phase profile of FIG. 2B may be 9D.

[0031] The inner radius (r in The outer radius (r ) may be greater than 0 mm and less than or equal to 5 mm, for example, 0.30 mm, 0.35 mm, 0.40 mm, 0.45 mm, 0.55 mm, 0.60 mm, 0.65 mm, or 0.70 mm. out ) may be greater than 0 mm and less than or equal to 5 mm, for example, 0.70 mm, 0.75 mm, 0.80 mm, 0.85 mm, 0.90 mm, 0.95 mm, 1.00 mm, 1.05 mm, 1.10 mm, 1.15 mm, 1.20 mm, 1.25 mm, or 1.30 mm. The outer radius of the phase profile of the phase ring structure may be proportional to the inner radius. For example, the relationship between the inner radius and the outer radius is 1≦r out / r in It can be expressed as ≦3.

[0032] The phase profile (Φ (n) (r) can be between 0 and 8π. In other words, 0 ≤ |Φ (n) (r)|≦8π. The height ratio between the inner and outer regions of the phase ring structure corresponding to the phase profiles of FIGS. 2A to 2C is 0 to 4π, or in other words, 0≦Φ (n) (r out )-Φ (n) (r in)≦4π.

[0033] In some embodiments, the phase profile shown in FIG. 2B may differ from the phase profile shown in FIG. 2A at least because in the phase profile shown in FIG. 2A the height profile of the inner region may be smaller than the height profile of the outer region, while in the phase profile shown in FIG. 2B the height profile of the inner region may be larger than the height profile of the outer region.

[0034] 2C illustrates a phase profile of a phase ring structure of an EDOF ophthalmic lens according to some embodiments of the present disclosure. The phase profile illustrated in FIG. 2C may include one or more features of the phase profiles described above with respect to FIGS. 2A-2B. For example, a phase ring structure corresponding to the phase profile illustrated in FIG. 2C may include an inner region and an outer region, whereby an inner radius (r in ) may extend from the optical axis of the lens to the outer edge of the inner region of the phase ring structure, and the outer radius (r out ) may extend from the optical axis to an outer edge of the outer region of the phase ring structure. The inner region may include a first phase ring surface having a first curvature and the outer region may include a second phase ring surface having a second curvature. The phase profile provided in FIG. 2C may correspond to at least Modulation Transfer Function (MTF) examples 4-5 shown in FIGS. 7-8, respectively, each of which is described in more detail below. The phase ring structure shown in FIG. 2C has a net add power of 3.35D. TIFF2025501395000006.tif8128. The theoretical add power of a lens without the phase ring structure corresponding to the phase profile of FIG. 2C may be 10.05D.

[0035] The inner radius (r in The outer radius (r ) may be greater than 0 mm and less than or equal to 5 mm, for example, 0.30 mm, 0.35 mm, 0.40 mm, 0.45 mm, 0.55 mm, 0.60 mm, 0.65 mm, or 0.70 mm. out) may be greater than 0 mm and less than or equal to 5 mm, for example, 0.70 mm, 0.75 mm, 0.80 mm, 0.85 mm, 0.90 mm, 0.95 mm, 1.00 mm, 1.05 mm, 1.10 mm, 1.15 mm, 1.20 mm, 1.25 mm, or 1.30 mm. The outer radius of the phase profile of the phase ring structure may be proportional to the inner radius. For example, the relationship between the inner radius and the outer radius is 1≦r out / r in It can be expressed as ≦3.

[0036] In some embodiments, the phase profile shown in FIG. 2C may differ from the phase profile shown in FIG. 2A at least because in the phase profile shown in FIG. 2A the height profile of the inner region may be smaller than the height profile of the outer region, while in the phase profile shown in FIG. 2C the height profile of the inner region may be larger than the height profile of the outer region.

[0037] 3 illustrates a height profile of an aspheric base curve in combination with a phase ring structure, according to some embodiments of the present disclosure. As described in more detail below (at least with respect to formula (VI)), the height profile of the combined structure can be the sum of the height profile of the aspheric base curvature and the height profile of the phase ring structure.

[0038] 4-10 show the optical performance (MTF) of various extended depth of focus (EDOF) ophthalmic lenses having phase ring structures according to some embodiments of the present disclosure, each of which is described in more detail below in the Examples section provided.

[0039] FIG. 11 shows a flowchart 1100 illustrating the manufacture of a double-sided aspheric ophthalmic lens with a phase ring structure according to some embodiments of the present disclosure. For example, the method of flowchart 1100 may be used to manufacture the EDOF lens described above and / or the multifocal lens described below. In step 1101, a first aspheric surface may be manufactured. In step 1102, a second aspheric surface including a base curvature may be manufactured. In step 1103, a phase ring structure may be generated on the second aspheric surface, the phase ring structure including an inner region and an outer region. For example, the phase ring structure may be generated by cutting the aspheric surface using a lathe, which may have a cutting head made of a hard mineral such as diamond or sapphire; direct-write patterning using a high-energy beam such as a laser beam or an electron beam or similar method of ablating a surface; etching the surface using a photolithographic patterning process; or shaping the surface.

[0040] The inner region may include a first phase ring surface having a first curvature, and the outer region may include a second phase ring surface having a second curvature. An outer edge of the inner region may be adjacent to an inner edge of the outer region. The manufactured ophthalmic lens may produce a far focus and an extended focus. Optionally, in step 1104, an in situ image quality analysis of the double-sided aspheric phase ring structured lens may be performed. For example, an ISO Model Eye 2 may be used to measure the through-focus MTF using a TRIOPTICS OptiSpheric® IOL PRO 2 to determine whether the performance of the ophthalmic lens meets a predetermined quality standard.

[0041] 12A-12D illustrate a double-sided aspheric phase ring structured ophthalmic lens with extended depth of focus (EDOF) according to some embodiments of the present disclosure. FIG. 12A illustrates a top view of the EDOF ophthalmic lens 1200, FIG. 12B illustrates a detailed view of the phase ring structure of the EDOF ophthalmic lens 1200, FIG. 12C illustrates a cross-sectional view of the EDOF ophthalmic lens 1200, and FIG. 12D illustrates a cross-sectional view of the lens body of the EDOF ophthalmic lens 1200.

[0042] The lens 1200 can include an optically transparent discoid lens body 1201 having an optical diameter 1206 and a central thickness 1210, and a pair of haptics 1202 having an overall outer diameter 1207 that act as a flexible support for the IOL when implanted in a patient's eye. The lens body 1201 can include an anterior surface 1208, a posterior surface 1209, a central zone 1203, and a peripheral area 1204. As described above, the lens body 1201 can include an optical axis 1205 that extends transversely to the anterior surface 1208 and the posterior surface 1209. Those skilled in the art will appreciate that the optical axis 1205 is an imaginary axis for referencing the optical properties of the lens 1200. The pair of haptics 1202 can extend outward from the lens body 1201 to support the lens 1200 after it is implanted in a person's eye. In some embodiments, the haptics 1202 of the lens 1200 can hold the lens in place within the capsular bag.

[0043] In some embodiments, the lens body 1201 can have a biconvex shape. Other shapes for the lens body 1201 can include, but are not limited to, plano-convex, biconcave, plano-concave, or a combination of convex and concave shapes. In some embodiments, both the anterior surface 1208 and the posterior surface 1209 can incorporate aspheric structures to provide bilateral asphericity for the lens 1200.

[0044] As described above with respect to at least FIGS. 2A-2C, the lens 1200 can include a phase ring structure including one or more regions. The phase ring structure can be designed to provide focal depth and maximize focal energy with constructive phase matching according to non-diffracting beam principles. In some embodiments, the phase ring structure of the lens 1200 can include one, two, three, four, five or more regions. For example, the lens 1200 shown at least in FIGS. 12A-12B can include an inner region (also referred to herein as a central zone 1203) and an outer region 1211. The lens 1200 can include a phase ring structure on one or both sides of the lens. In some embodiments, the phase ring structure can be disposed on the rear surface of the lens. In some embodiments, the phase ring structure can be disposed on the rear surface because the rear surface has less light scattering effects than the front surface. As discussed above, each region may include or be bounded by one or more rings that extend across at least a portion of the rear surface of the lens body 1201 concentrically about an optical axis passing through the central zone 1203 (or inner region). In some embodiments, the regions may not be limited to concentric or annular ring-shaped regions, but may alternatively or additionally include concentric elliptical or oval-shaped regions.

[0045] In some embodiments, the optical diameter 1206 of the lens body 1201 can be about 4 mm or more, e.g., about 4.5 mm, 5 mm, 5.5 mm, 6 mm, 6.5 mm, 7 mm, 7.5 mm, or 8 mm. The total outer diameter 1207 of the lens 1200, including the haptics 1202, can be about 9 mm or more, e.g., 10 mm, 11 mm, 12 mm, 13 mm, 14 mm, 15 mm, 16 mm, 17 mm, or 18 mm. The lens body 1201 can have a center thickness 1210 of about 0.8 mm or more, e.g., 0.85 mm, 0.9 mm, 0.95 mm, 1.0 mm, 1.05 mm, 1.10 mm, 1.15 mm, or 1.20 mm. Those skilled in the art will appreciate that although FIGS. 12A-12B show an intraocular lens (IOL), other ophthalmic lenses, including multifocal diffractive contact lenses or spectacle lenses, can also benefit from this same approach. When used with ophthalmic multifocal contact lenses and eyeglass lenses, the haptics 1202 may not be provided.

[0046] The amount of correction an ophthalmic lens provides is called refractive power and is measured in diopters (D). Refractive power is calculated as the reciprocal of the focal length f measured in meters, which can be the respective focal length from the lens to the respective focal point for distance, intermediate or near vision. Lens body 1201 (and lens body 1601, described in more detail below) can provide a base refractive power that is about -15D to about +55D.

[0047] The ophthalmic lenses of the present disclosure, such as lens 1200 (and lens 1600, described in more detail below), can be made of a flexible material that allows temporary deformation to reduce the overall apparent circumference to facilitate its insertion into the cornea, thereby advantageously allowing the use of a reduced size corneal incision. In some embodiments, the lens body can include polypropylene, polycarbonate, polyethylene, acrylic butadiene styrene, polyamide, polychlorotrifluoroethylene, polytetrafluoroethylene, polyvinyl chloride, polyvinylidene fluoride, polyvinyl chloride, polydimethylsiloxane, polyethylene terephthalate, ethylene tetrafluoroethylene, ethylene chlorotrifluoroethylene, perfluoroalkoxy, polymethylpentene, polymethylmethacrylate, polystyrene, polyetheretherketone, tetrafluoroethylene, polyurethane, poly(methylmethacrylate), poly(2-hydroxyethylmethacrylate), nylon, polyether block amide, silicone, or mixtures thereof.

[0048] In some embodiments, the lens body can comprise a hydrophilic polymer made of monomers selected from the group consisting of 2-acrylamido-2-methylpropanesulfonic acid, 2-hydroxyethyl methacrylate, N-vinylpyrrolidone, vinylbenzyltrimethylammonium salt, diethylaminoethyl methacrylate, dimethylaminoethyl acrylate, dimethylaminoethyl methacrylate, diethylaminoethyl acrylate, diethylaminomethyl methacrylate, tert-butylaminoethyl acrylate, tert-butylaminoethyl methacrylate and dimethylaminopropylacrylamide, acrylic acid, methacrylic acid, styrenesulfonic acid and their salts, hydroxypropyl acrylate, vinylpyrrolidone, dimethylacrylamide, ethylene glycol monomethacrylate, ethylene glycol monoacrylate, ethylene glycol dimethacrylate, ethylene glycol diacrylate, triethylene glycol diacrylate and triethylene glycol methacrylate. In some embodiments, these hydrophilic monomers are surface grafted to the above-mentioned polymer matrix to make the lens body. In some embodiments, the ophthalmic lenses of the present disclosure can be made with polymer compositions according to U.S. Pat. No. 10,494,458, entitled "Functionalized hydrophilic and lubricious polymeric matrix and methods of using same," which is incorporated by reference herein in its entirety.

[0049] As mentioned above, the ophthalmic lens of the present disclosure can be an intraocular lens (IOL). The haptics of the IOL of the present disclosure can be made of polymeric materials including polymethacrylate, polypropylene, polyethylene, polystyrene, and polyacrylate.

[0050] The surfaces of IOLs can include spherical, aspheric and / or toric elements. Spherical surfaces can produce spherical aberration, a type of optical defect that can cause increased glare and reduced overall quality of vision, especially in low light and darkness. Aspheric lenses can correct spherical aberration. Aspheric IOLs can provide improved contrast sensitivity, enhanced functional visual acuity and superior night driving capabilities.

[0051] Toric elements are usually used to correct astigmatic eyes. In general, astigmatism is an optical defect in which vision is blurred due to the eye's inability to focus a point object into a sharp image on the retina. This inability can be due to irregular curvatures of the cornea and / or lens. The refractive error of an astigmatic eye is due to the degree of curvature of different meridians of the cornea and / or lens, and thus the difference in the degree of refraction (leading to the eye having two foci, one for each meridian). A meridian as used herein includes one of two axes relative to a curved surface, such as the prime meridian of the Earth. A meridian can be orthogonal. By way of illustration, a meridian of the Earth can be any orthogonal meridian and any parallel that curves along the surface of the Earth.

[0052] For example, in an astigmatic eye, an image may be clearly focused on the retina in the horizontal (sagittal) plane, but may be focused behind the retina in the vertical (tangential) plane. If the astigmatism arises from the cornea alone, the two astigmatism meridians may be the two axes of the cornea. If the astigmatism arises from the lens, the two astigmatism meridians may be the two axes of the lens. If the astigmatism arises from a combination of the cornea and lens, the two astigmatism meridians may be the respective axes of the combined cornea and lens lens.

[0053] Astigmatism resulting from the cornea or crystalline lens or a combination of the two lenses can be corrected by lenses containing a toric component. A toric surface resembles a portion of the surface of a football, with two regular radii of curvature, one smaller than the other. These radii of curvature can be used to correct defocus in two meridians of an astigmatic eye. Thus, blurred vision caused by astigmatism can be corrected by corrective lenses or laser vision correction, such as spectacles, hard contact lenses, contact lenses and / or intraocular lenses (IOLs), that provide corrective optics specifically rotated around the optical axis.

[0054] In some embodiments, an ophthalmic lens according to the present disclosure can provide distance vision for viewing objects at distances ranging from about infinity to about 6 meters (m). In some embodiments, one or more lenses of the present disclosure can provide near vision for viewing objects at distances less than about 3 m. In some embodiments, a lens of the present disclosure can provide intermediate vision for viewing objects at distances ranging from about 0.3 m to about 1 m, about 2 m, about 3 m, about 4 m, about 5 m, or about 6 m. As a result, a lens of the present disclosure can advantageously provide a degree of accommodation, usually referred to as pseudoaccommodation, for different distance ranges. In some embodiments, when implanted in a patient's eye, the combined refractive power of the eye's cornea and the near, intermediate, and far vision refractive powers of the ophthalmic lens of the present disclosure can focus light emanating from objects within near, intermediate, and far distance ranges from the patient onto the retina. In some embodiments, the far focus (f0) and extended focus (f1) provided by an IOL of the present disclosure can be defined by the following formula: TIFF2025501395000007.tif10128 formula, TIFF2025501395000008.tif8128 represents the theoretical addition power, TIFF2025501395000009.tif8128 represents the actual addition power.

[0055] Multifocal Ophthalmic Lenses In some embodiments, a bi-aspheric multifocal lens design with a phase ring structure may be provided to improve distance and near vision. A multifocal lens may minimize undesirable visual effects such as dysphotopsia (glare, halos, etc.) experienced during use of an ophthalmic lens, especially during nighttime use. Figures 13A-13B show various phase profiles of a phase ring structure of a multifocal ophthalmic lens according to some embodiments of the present disclosure. The phase profile of the phase ring structure may correspond to the full height profile of the phase ring structure, as described below in connection with the height profile formula provided in Formula (II) below. As described above, the phase ring structure of the lenses provided herein may include a series of concentric circular regions, such as two, three, four or more regions. Figures 13A-13B show the respective regions based on radius in the corresponding phase profile diagrams.

[0056] For example, FIG. 13A shows the inner radius (r in ), intermediate radius (r int ) and the outer radius (r out ) where the inner radius extends from the optical axis of the lens to the outer edge of the inner region of the phase ring structure, the middle radius extends from the optical axis to the outer edge of the middle region of the phase ring structure, and the outer radius extends from the optical axis to the outer edge of the outer region of the phase ring structure. The phase profile provided in FIG. 13A may correspond to Modulation Transfer Function (MTF) Examples 8-9 shown in FIGS. 15A-15B, respectively, each of which will be described in further detail below with reference to examples provided herein. The phase ring structure shown in FIG. 13A may have a real add power that is 3.5D, where the real add power is the difference between the add power at the far focus and the add power at the extended focus. The actual add power of a lens having a phase ring structure corresponding to the phase profile of FIG. 13A is expressed as the theoretical add power of a lens without the phase ring structure. TIFF2025501395000011.tif8128. For example, the theoretical add power of a lens without a phase ring structure corresponding to the phase profile of FIG. 13A may be 12.0D, which can be determined using the following formula (III). As described above, the phase ring structure can be designed to provide focal depth and maximize focal energy using constructive phase matching through the non-diffractive beam principle. Therefore, constructive interference in a multifocal lens can generate near, intermediate and far foci when the refraction of light passes through the inner, middle and outer regions.

[0057] In some embodiments, the inner region of the phase ring structure may include a first phase ring surface having a first curvature. The curvatures described herein may include one or more continuous arcs, parabolas, and / or lines. As illustrated, the first curvature may be monotonically decreasing (e.g., negatively sloped) as it extends outward from the optical axis of the lens. The first curvature may include a first (inner) sloped portion sloped at a first angle relative to the optical axis of the ophthalmic lens and a second (outer) sloped portion sloped at a second angle relative to the optical axis. Both the first sloped portion and the second sloped portion may be monotonically sloped relative to the optical axis of the ophthalmic lens. The first angle may be greater than the second angle such that the slope of the inner sloped portion is less than the slope of the outer sloped portion. The inner radius (r in ) may be greater than 0 mm and less than or equal to 5 mm, for example, 0.30 mm, 0.35 mm, 0.40 mm, 0.45 mm, 0.55 mm, 0.60 mm, 0.65 mm, or 0.70 mm.

[0058] In some embodiments, the intermediate region of the phase ring structure may include a second phase ring surface having a second curvature. The second curvature may include a first (inner) sloping portion sloping at a third angle relative to the optical axis of the ophthalmic lens and a second (outer) sloping portion sloping at a fourth angle relative to the optical axis. As shown, the second curvature may not monotonically increase or decrease in a direction extending outward from the optical axis of the lens. Rather, the inner and outer sloping portions may be sloped in different directions. The intermediate radius (rint ) can be greater than 0 mm and less than or equal to 5 mm, for example, 0.70 mm, 0.75 mm, 0.80 mm, 0.85 mm, 0.90 mm, 0.95 mm, 1.00 mm, 1.05 mm, 1.10 mm, 1.15 mm, 1.20 mm, 1.25 mm, or 1.30 mm.

[0059] In some embodiments, the outer region of the phase ring structure may include a third phase ring surface having a third curvature. The third curvature may include a first (inner) sloping portion sloping at a fifth angle relative to the optical axis of the ophthalmic lens and a second (outer) sloping portion sloping at a sixth angle relative to the optical axis. As shown, the third curvature may not monotonically increase or decrease in a direction outward from the optical axis of the lens. Rather, the inner and outer sloping portions may slope in different directions. The outer radius (r out ) may be greater than 0 mm and less than or equal to 5 mm, for example, 0.70 mm, 0.75 mm, 0.80 mm, 0.85 mm, 0.90 mm, 0.95 mm, 1.00 mm, 1.05 mm, 1.10 mm, 1.15 mm, 1.20 mm, 1.25 mm, or 1.30 mm. The outer radius of the phase profile of the phase ring structure may be proportional to the inner radius. For example, the relationship between the inner radius and the outer radius is 1≦r out / r in It can be expressed as ≦3.

[0060] In some embodiments, the outer edge of the inner region of the phase ring structure may be adjacent to the inner edge of the outer region of the phase ring structure. Similarly, the outer edge of the intermediate region may be adjacent to the inner edge of the outer region of the phase ring structure. As shown in FIG. 13A, the transition between the first curvature and the second curvature may include a minimum in the phase profile because at least the slope direction (negative) of the outer slope portion of the first curvature may be opposite to the slope direction (positive) of the inner slope portion of the second curvature. Similarly, the transition between the second curvature and the third curvature may include a minimum in the phase profile because at least the slope direction (positive) of the outer slope portion of the second curvature may be opposite to the slope direction (negative) of the inner slope portion of the third curvature. The second phase ring surface and the third phase ring surface may include a maximum in the phase profile because at least the slope direction (positive) of the inner slope portion of the second curvature and the third curvature may be opposite to the slope direction (negative) of the outer slope portion. The minimum and maximum may correspond to the position of the ring in the phase ring structure. The area between the minimum and maximum may be referred to as the transition area between two rings in some embodiments.In some embodiments, one or more rings in the phase ring structure may be located between the rings corresponding to the minimum and / or maximum.Therefore, the minimum and maximum in the phase profile may provide a raised design in the profile of the lens surface profile, whereby at least the raised portion in the surface profile may correspond to the ring in the phase ring structure.

[0061] 13B illustrates a phase profile of a phase ring structure of a multifocal ophthalmic lens according to some embodiments of the present disclosure. The phase profile illustrated in FIG. 13B may include one or more features of the phase profile described above with respect to FIG. 13A. For example, a ring structure corresponding to the phase profile illustrated in FIG. 13B may include an inner region, a middle region, and an outer region, thereby defining an inner radius (r in ) may extend from the optical axis of the lens to the outer edge of the inner region of the phase ring structure, with the intermediate radius (r int ) may extend from the optical axis to the outer edge of the intermediate region of the phase ring structure, and the outer radius (r out) may extend from the optical axis to the outer edge of the outer region of the phase ring structure. The inner region may include a first phase ring surface having a first curvature, the middle region may include a second phase ring surface having a second curvature, and the outer region may include a third phase ring surface having a third curvature. The phase profile provided in FIG. 13B may correspond to Modulation Transfer Function (MTF) Example 12 shown in FIG. 15C, which is described in more detail below. The phase ring structure shown in FIG. 13B has a net add power of 3.35D. TIFF2025501395000012.tif8128. The theoretical add power of a lens without the phase ring structure corresponding to the phase profile of FIG. 13B may be 12D.

[0062] The inner radius (r in The intermediate radius (r ) may be greater than 0 mm and less than or equal to 5 mm, for example, 0.30 mm, 0.35 mm, 0.40 mm, 0.45 mm, 0.55 mm, 0.60 mm, 0.65 mm, or 0.70 mm. int The outer radius (r ) may be greater than 0 mm and less than or equal to 5 mm, for example, 0.70 mm, 0.75 mm, 0.80 mm, 0.85 mm, 0.90 mm, 0.95 mm, 1.00 mm, 1.05 mm, 1.10 mm, 1.15 mm, 1.20 mm, 1.25 mm, or 1.30 mm. out ) may be greater than 0 mm and less than or equal to 5 mm, for example, 0.70 mm, 0.75 mm, 0.80 mm, 0.85 mm, 0.90 mm, 0.95 mm, 1.00 mm, 1.05 mm, 1.10 mm, 1.15 mm, 1.20 mm, 1.25 mm, or 1.30 mm. The outer radius of the phase profile of the phase ring structure may be proportional to the inner radius.

[0063] The phase profile (Φ (n) (r) can be between 0 and 8π. In other words, 0 ≤ |Φ (n)(r)|≦8π. The height ratio between the inner region and the intermediate region, between the inner region and the outer region, and / or between the intermediate region and the outer region of the phase ring structure corresponding to the phase profile of FIGS. 13A to 13B is 0 to 4π, or in other words, 0≦Φ (n) (r out )-Φ (n) (r in )≦4π.

[0064] In some embodiments, the phase profile shown in FIG. 13B may differ from the phase profile shown in FIG. 13A at least because in the phase profile shown in FIG. 13B the height profile of the inner region may be smaller than the height profile of the middle and / or outer region, while in the phase profile shown in FIG. 13A the height profile of the inner region may be substantially the same as the height profile of the middle and / or outer region.

[0065] 14 shows a height profile of an aspheric base curve combined with a phase ring structure for a multifocal lens according to some embodiments of the present disclosure. As explained in more detail below (Equation (VI)), the height profile of the combined structure can be the sum of the height profile of the aspheric base curvature and the height profile of the phase ring structure.

[0066] 15A-15C show the optical performance (MTF) of various multifocal ophthalmic lenses having phase ring structures according to some embodiments of the present disclosure, each of which is described in more detail below in the Examples section provided.

[0067] 16A-16D illustrate a double-sided aspheric multifocal ophthalmic lens having a phase ring structure according to some embodiments of the present disclosure. FIG 16A illustrates a plan view of the multifocal ophthalmic lens 1600, FIG 16B illustrates a detailed view of the phase ring structure of the multifocal ophthalmic lens 1600, FIG 16C illustrates a cross-sectional view of the multifocal ophthalmic lens 1600, and FIG 16D illustrates a cross-sectional view of the lens body of the multifocal ophthalmic lens 1600.

[0068] The lens 1600 may include any one or more features of the lens 1200 described above with respect to FIGS. 12A-12D. For example, the lens 1600 may include an optically transparent, discoid lens body 1601 having an optical diameter 1606 and a central thickness 1610, and a pair of haptics 1602 having an overall outer diameter 1607 that act as a flexible support for the IOL when implanted in a patient's eye. The lens body 1601 may include an anterior surface 1608, a posterior surface 1609, a central zone 1603, and a peripheral area 1604. As described above, the lens body 1601 may include an optical axis 1605 that extends transversely to the anterior surface 1608 and the posterior surface 1609. The pair of haptics 1602 may extend outwardly from the lens body 1601 to support the lens 1600 after it is implanted in a person's eye. In some embodiments, the haptics 1602 of the lens 1600 may hold the lens in place within the capsular bag.

[0069] In some embodiments, the lens body 1601 can have a biconvex shape, similar to the lens body 1201. Other shapes for the lens body 1601 can include, but are not limited to, plano-convex, biconcave, plano-concave, or a combination of convex and concave shapes. In some embodiments, both the anterior surface 1608 and the posterior surface 1609 can also incorporate aspheric structures to provide bilateral asphericity for the lens 1600.

[0070] As described above with respect to at least FIGS. 13A-13B, the lens 1600 may include a phase ring structure including one or more regions. The phase ring structure may be designed to provide focal depth and maximize focal energy with constructive phase matching according to non-diffracting beam principles. In some embodiments, the phase ring structure of the lens 1600 may include one, two, three, four, five or more regions. For example, the lens 1600 shown at least in FIGS. 16A-16B may include an inner region (also referred to herein as a central zone 1603), a middle region 1612 and an outer region 1611. The lens 1600 may include a phase ring structure on one or both sides of the lens. In some embodiments, the phase ring structure may be disposed on the rear surface of the lens. As described above, each region may include or be bounded by one or more rings that extend across at least a portion of the rear surface of the lens body 1601 concentrically with respect to an optical axis passing through the central zone 1603 (or inner region). In some embodiments, the regions may not be limited to concentric circular or annular ring shaped regions, but may alternatively or additionally include concentric elliptical or oval shaped regions.

[0071] In some embodiments, the optical diameter 1606 of the lens body 1601 can be about 4 mm or more, e.g., about 4.5 mm, 5 mm, 5.5 mm, 6 mm, 6.5 mm, 7 mm, 7.5 mm, or 8 mm. The overall outer diameter 1607 of the lens 1600, including the haptics 1602, can be about 9 mm or more, e.g., 10 mm, 11 mm, 12 mm, 13 mm, 14 mm, 15 mm, 16 mm, 17 mm, or 18 mm. The lens body 1601 can have a center thickness 1610 of about 0.8 mm or more, e.g., 0.85 mm, 0.9 mm, 0.95 mm, 1.0 mm, 1.05 mm, 1.10 mm, 1.15 mm, or 1.20 mm. Those skilled in the art will appreciate that although FIGS. 16A-16B show an intraocular lens (IOL), other ophthalmic lenses, including multifocal diffractive contact lenses or spectacle lenses, can also benefit from this same approach. When used with ophthalmic multifocal contact lenses and eyeglass lenses, the haptics 1602 may not be provided.

[0072] Phase ring structure governing equations The above-described phase ring structures embodied in the extended depth of focus and multifocal ophthalmic lenses of the present disclosure can be designed using formulas (I)-(IV) detailed below.

[0073] Pupil Function The pupil function is a lens characteristic function that represents the physical effect of a lens that can change the state of light incident on the lens. Specifically, as shown in the following formula (I), the pupil function is expressed by the amplitude function A(r) and the phase function Φ (n) It is expressed by multiplying it with the exponential function of (r). TIFF2025501395000013.tif5128T(r): Pupil function A(r): Amplitude function Φ (n) (r): Phase function n: natural number

[0074] Phase Function A phase function is defined as a mathematical function that represents the physical effect a lens provides, such as changing in some way the phase of light incident on the lens (the position of the peaks and valleys of the waveform). The variables of the phase function are primarily expressed by the radial position r from the center of the lens, and the phase of light incident on the lens at position r is expressed by the phase function Φ (n) (r) and is emitted from the lens. Specifically, this is represented by the r-Φ coordinate system. In this disclosure, the phase is written as Φ and the unit is radian. For example, one wavelength of light is represented as 2π radians, and half the wavelength is represented as π radians. The distribution of the phase in the entire area where the phase function is provided and expressed in the same coordinate system is called the phase profile, or simply the profile or zone profile. If the r-axis of Φ=0 is taken as the reference line, this means that the light incident on the point of Φ=0 is emitted without changing the phase. Also, for this reference line, if a positive value is used for Φ, it means that the light travels slower by that phase amount, and if a negative value is used for Φ, it means that the light travels faster by that phase amount. In an actual ophthalmic lens, a refractive surface that is not provided with a diffractive structure corresponds to this reference line (surface). The light is emitted from the lens with a phase change based on this phase function.

[0075] Amplitude Function The amplitude function is a function represented by A(r) in the above formula (I). In the present disclosure, this is defined as a function that represents the change in the amount of light transmitted when passing through a lens. The variable of the amplitude function is represented as the radial position r from the center of the lens, and represents the transmittance of the lens at the point of position r. The amplitude function is in the range of 0 to 1, which means that at the point A(r)=0, no light is transmitted, and at the point A(r)=1, the incident light is transmitted as it is without loss.

[0076] zone In this disclosure, a zone is used as the smallest unit of a phase ring structure, element or diffraction grating provided on a lens. A zone may be circular or annular, and may be bounded by a ring along the inner radius and / or along the outer radius. For example, a first zone may be a circular zone (i.e., the first ring) bounded only by a ring along the outer radius, and for each subsequent zone, the annular zone between the (n-1)th ring and the nth ring may be called the nth zone.

[0077] The height profile (Z phase ) can be calculated based on the following formula (II): In some embodiments, the height can be based on one period (2π, which can be about 3.35 μm), the refractive index of the lens and the medium covering the lens, and the wavelength used (e.g., green light having a wavelength of about 550 nm). TIFF2025501395000014.tif8128Z phase (r): Height profile of the phase ring structure Φ (n) (r): Phase function λ: Design wavelength n1: Refractive index of the lens material n0: Refractive index of the medium covering the lens

[0078] The outer radius of a particular zone (r n ) can be calculated based on the following formula (III): TIFF2025501395000015.tif6128r n :Outer radius of the nth zone λ: Design wavelength f: reciprocal of add power

[0079] Phase function (Φ (n) (r) can be calculated according to the following formula (IV): TIFF2025501395000016.tif8128Φ (n) (r): Phase function f(r): Phase function based profile r: radial distance from the center of the lens r n :Outer radius of the nth zone r n+1 :Outer radius of the (n+1)th zone

[0080] The phase function base profile f(r) can be a linear, parabolic, sinusoidal or polynomial function. A and D are light distribution parameters. A is an amplitude scale factor and D is a vertical shift, where +D moves the function up and -D moves the function down. In some embodiments, A (n) can be the ratio of the phase function base profiles, D (n) can be the phase shift of the phase function based profile. As shown below with respect to the examples provided herein, the parameter A can correspond to the tilt of the phase ring structure of the various zones.

[0081] The double-sided aspheric structure (front and rear surfaces of the optical zone of the ophthalmic lens) is for the correction of the spherical aberration of the lens. The height profile (Z asp ) can be calculated according to the following formula (V): TIFF2025501395000017.tif9128Z asp : Height profile of aspheric structure r: radial distance from the center of the lens k: conic constant c: curvature A i : High-order aspheric coefficients

[0082] When both the aspheric structure and the phase ring structure are disposed on the same surface (the anterior and / or posterior surface of the ophthalmic lens), according to some aspects of the present disclosure, the height profile (Z total ) is the height profile of the aspheric base curvature (Z asp ) and the height profile (Z phase ) is the sum of TIFF2025501395000018.tif5128Z phase : Height profile of phase ring structure Z asp : Height profile of aspheric structure Z total : Combination structure, i.e., height profile of the lens body

[0083] In some embodiments, the ophthalmic lens can be a contact lens or an intraocular lens (IOL). In some embodiments, the IOL can be an intracorneal IOL, an anterior chamber IOL, or a posterior chamber IOL. Although haptic arms are shown in the embodiments, in the case of a posterior chamber IOL, any haptic fixation structure suitable for the capsular bag or ciliary sulcus that is compatible with posterior chamber implantation can be used.

[0084] One method of estimating the optical priority of an ophthalmic lens involves experimentally determining its Modulation Transfer Function (MTF). The MTF of an optical system can be measured according to Annex C of ISO 11979-2, which reflects the percentage of contrast transmitted through the optical system for a determined spatial frequency of a test pattern, where this frequency is defined as "cycles / mm" or "LP / mm" (where "LP" stands for "line pair"). In general, contrast decreases with increasing spatial frequency.

[0085] Below, examples are presented that detail various aspects of the IOL discussed above.The following examples are provided to further illustrate aspects of the present disclosure, but are not intended to limit the scope of the present disclosure.These are typical of those that may be used, but other techniques, methodologies, or technologies known to those skilled in the art may be used instead. EXAMPLES

[0086] 4-10 and 15A-15C show the optical performance (MTF) of various ophthalmic lenses having a phase ring structure, according to at least the following examples. As described above, the phase ring structure may include one or more zones, and the zones are bounded by one or more rings. For example, the formula (III) may be used to measure the radial distance from the optical axis to a given nth ring on the lens.

[0087] The MTF of extended depth of focus (EDOF) and multifocal lenses may differ at different apertures and / or resolution measurements. For example, at a 2 mm aperture and a 50 LP / mm resolution measurement, an MTF value greater than 0.05 may indicate an EDOF lens design, as evidenced by one local maximum (e.g., curve (2) in Figs. 4-10). On the other hand, an MTF value less than 0.05 may indicate a multifocal lens design, as evidenced by two local maxima (e.g., curve 2 in Figs. 15A-C).

[0088] Example 1: MTF of an EDOF ophthalmic lens according to the first aspect of the present disclosure Figure 4 shows the optical performance (MTF) of an extended depth of focus (EDOF) ophthalmic lens with a phase ring structure according to the first embodiment of the present disclosure. The MTF in Figure 4 can correspond to the phase profile shown in Figure 2A. The parameters A and D according to formula (IV) (above) are varied as shown in Table 1 below.

[0089] Table 1: Variations of parameters A and D in the first embodiment of the present disclosure TIFF2025501395000019.tif46128

[0090] Curve (1) shows the MTF with a 3 mm aperture and a measured resolution of 50 LP / mm. Curve (2) shows the MTF with a 2 mm aperture and a measured resolution of 50 LP / mm. Curve (3) shows the MTF with a 3 mm aperture and a measured resolution of 50 LP / mm in single focus mode. Curve (4) shows the MTF with a 2 mm aperture and a measured resolution of 50 LP / mm in single focus mode. Curves (1)-(4) in FIG. 4 are for an add power of approximately 2.4D. TIFF2025501395000020.tif8128 shows focus at approximately 21.5D.

[0091] In some embodiments, each ring listed in Table 1 may correspond to a given point or series of points on the phase profile of the phase ring structure. For example, FIG. 2A includes annotations (1)-(4) and (8), each of which may correspond to rings 1-4 and 8, respectively, in Table 1 above. As shown, ring 1 may correspond to a position where the phase ring structure transitions between a first inner sloping portion of the inner region and a first outer sloping portion of the inner region. Ring 2 may correspond to a position where the phase ring structure transitions between the inner region and the outer region (i.e., a position where the outer edge of the inner region is adjacent to the inner edge of the outer region). Ring 3 may correspond to a position where the phase ring structure transitions between a second inner sloping portion of the outer region and an intermediate sloping portion of the outer region. Ring 4 may correspond to a position where the phase ring structure transitions from an intermediate sloping portion of the outer region to a second outer sloping portion. Ring 8 may correspond to a position where the phase ring structure of the lens transitions to the base curvature of the lens. Each ring not explicitly listed above may be located within a given sloping portion of the phase ring structure. For example, rings 5, 6 and 7 may be located between rings 4 and 8 in the second outer tapered portion of the phase ring structure.

[0092] Example 2: MTF of an EDOF ophthalmic lens according to the second aspect of the present disclosure Fig. 5 shows the optical performance (MTF) of the EDOF ophthalmic lens with phase ring structure according to the second embodiment of the present disclosure. The MTF of Fig. 5 can correspond to the phase profile shown in Fig. 2A. The parameters A and D according to formula (IV) are various, as shown in Table 2 below.

[0093] Table 2: Variations of parameters A and D in the second embodiment of the present disclosure TIFF2025501395000021.tif46128

[0094] Curve (1) shows the MTF with a 3 mm aperture and a measured resolution of 50 LP / mm. Curve (2) shows the MTF with a 2 mm aperture and a measured resolution of 50 LP / mm. Curve (3) shows the MTF with a 3 mm aperture and a measured resolution of 50 LP / mm in single focus mode. Curve (4) shows the MTF with a 2 mm aperture and a measured resolution of 50 LP / mm in single focus mode. Curves (1)-(4) in FIG. 5 are for an add power of approximately 2.4D. TIFF2025501395000022.tif8128 shows focus at approximately 21.5D.

[0095] In some embodiments, each ring set forth in Table 2 may correspond to a given point or series of points on a topological profile of the topological ring structure. For example, FIG. 2A includes annotations (1)-(4) and (8), each of which may correspond to rings 1-4 and 8, respectively, in Table 2 above. The locations of one or more rings from Table 2 in the topological profile of FIG. 2A may be substantially the same as those described above with respect to Example 1.

[0096] Example 3: MTF of an EDOF ophthalmic lens according to the third aspect of the present disclosure Fig. 6 shows the optical performance (MTF) of the EDOF ophthalmic lens with phase ring structure according to the third embodiment of the present disclosure. The MTF of Fig. 6 can correspond to the phase profile shown in Fig. 2A. The parameters A and D according to formula (IV) are various, as shown in Table 3 below.

[0097] Table 3: Variations of parameters A and D in the third embodiment of the present disclosure TIFF2025501395000023.tif46128

[0098] Curve (1) shows the MTF with a 3 mm aperture and a measured resolution of 50 LP / mm. Curve (2) shows the MTF with a 2 mm aperture and a measured resolution of 50 LP / mm. Curve (3) shows the MTF with a 3 mm aperture and a measured resolution of 50 LP / mm in single focus mode. Curve (4) shows the MTF with a 2 mm aperture and a measured resolution of 50 LP / mm in single focus mode. Curves (1)-(4) in FIG. 6 are for an add power of approximately 2.4D. TIFF2025501395000024.tif8128 shows focus at approximately 20.5D.

[0099] In some embodiments, each ring set forth in Table 3 may correspond to a given point or series of points on a topological profile of the topological ring structure. For example, FIG. 2A includes annotations (1)-(4) and (8), each of which may correspond to rings 1-4 and 8, respectively, of Table 3 above. The location of one or more rings from Table 3 in the topological profile of FIG. 2A may be substantially the same as the locations described above with respect to Examples 1 and / or 2.

[0100] Example 4: MTF of an EDOF ophthalmic lens according to the fourth aspect of the present disclosure Fig. 7 shows the optical performance (MTF) of the EDOF ophthalmic lens with phase ring structure according to the fourth embodiment of the present disclosure. The MTF of Fig. 7 can correspond to the phase profile shown in Fig. 2C. The parameters A and D according to formula (IV) are various, as shown in Table 4 below.

[0101] Table 4: Variations of parameters A and D in the fourth aspect of the present disclosure TIFF2025501395000025.tif66128

[0102] Curve (1) shows the MTF with a 3 mm aperture and a measured resolution of 50 LP / mm. Curve (2) shows the MTF with a 2 mm aperture and a measured resolution of 50 LP / mm. Curve (3) shows the MTF with a 3 mm aperture and a measured resolution of 50 LP / mm in single focus mode. Curve (4) shows the MTF with a 2 mm aperture and a measured resolution of 50 LP / mm in single focus mode. Curves (1)-(4) in FIG. 7 are for an add power of approximately 3.35D. TIFF2025501395000026.tif8128 shows focus at approximately 20.5D.

[0103] In some embodiments, each ring listed in Table 4 may correspond to a given point or series of points on the topological profile of the phase ring structure. For example, FIG. 2C includes annotations (1), (3), (4), (8), (9), and (12), each of which may correspond to rings 1, 3, 4, 8, 9, and 12, respectively, in Table 4 above. As shown, ring 1 may correspond to a position where the phase ring structure transitions between a first inner sloping portion and a first outer sloping portion of the inner region. Ring 3 may correspond to a position where the phase ring structure transitions between the inner region and the outer region (i.e., a position where the outer edge of the inner region is adjacent to the inner edge of the outer region). Ring 4 may correspond to a position where the phase ring structure transitions between a second inner sloping portion and a first intermediate sloping portion. Ring 8 may correspond to a position where the phase ring structure transitions from a first intermediate sloping portion to a second intermediate sloping portion of the outer region. Ring 9 may correspond to a position where the phase ring structure transitions from a second intermediate sloping portion to a second outer sloping portion of the outer region. Ring 12 may correspond to a location where the phase ring structure of the lens transitions into the base curvature of the lens. Each ring not explicitly listed above may be located within a given sloped portion of the phase ring structure. For example, ring 2 may be located between ring 1 and ring 3 in a first outer sloped portion of the phase ring structure. Rings 5, 6, and 7 may be located between ring 4 and ring 8 in a first intermediate sloped portion of the phase ring structure. Rings 10 and 11 may be located between ring 9 and ring 12 in a second outer sloped portion of the phase ring structure.

[0104] Example 5: MTF of an EDOF ophthalmic lens according to the fifth aspect of the present disclosure Fig. 8 shows the optical performance (MTF) of the EDOF ophthalmic lens with phase ring structure according to the fifth embodiment of the present disclosure. The MTF of Fig. 8 can correspond to the phase profile shown in Fig. 2C. The parameters A and D according to formula (IV) are various, as shown in Table 5 below.

[0105] Table 5: Variations of parameters A and D in the fifth aspect of the present disclosure TIFF2025501395000027.tif66128

[0106] Curve (1) shows the MTF with a 3 mm aperture and a measured resolution of 50 LP / mm. Curve (2) shows the MTF with a 2 mm aperture and a measured resolution of 50 LP / mm. Curve (3) shows the MTF with a 3 mm aperture and a measured resolution of 50 LP / mm in single focus mode. Curve (4) shows the MTF with a 2 mm aperture and a measured resolution of 50 LP / mm in single focus mode. Curves (1)-(4) in FIG. 8 are for an add power of approximately 3.35D. TIFF2025501395000028.tif8128 shows focus at approximately 20.5D.

[0107] In some embodiments, each ring set forth in Table 5 may correspond to a given point or series of points on the topological profile of the topological ring structure. For example, FIG. 2C includes annotations (1), (3), (4), (8), (9), and (12), each of which may correspond to rings 1, 3, 4, 8, 9, and 12, respectively, of Table 5 above. The location of one or more rings from Table 5 in the topological profile of FIG. 2C may be substantially the same as the locations described above with respect to Example 4.

[0108] Example 6: MTF of an EDOF ophthalmic lens according to the sixth aspect of the present disclosure Fig. 9 shows the optical performance (MTF) of the EDOF ophthalmic lens with phase ring structure according to the sixth embodiment of the present disclosure. The MTF of Fig. 9 can correspond to the phase profile shown in Fig. 2B. The parameters A and D according to formula (IV) are various, as shown in Table 6 below.

[0109] Table 6: Variations of parameters A and D in the sixth aspect of the present disclosure TIFF2025501395000029.tif66128

[0110] Curve (1) shows the MTF with a 3 mm aperture and a measured resolution of 50 LP / mm. Curve (2) shows the MTF with a 2 mm aperture and a measured resolution of 50 LP / mm. Curve (3) shows the MTF with a 3 mm aperture and a measured resolution of 50 LP / mm in single focus mode. Curve (4) shows the MTF with a 2 mm aperture and a measured resolution of 50 LP / mm in single focus mode. Curves (1)-(4) in FIG. 9 are for an add power of approximately 3.0 D. TIFF2025501395000030.tif8128 shows focus at approximately 20.5D.

[0111] In some embodiments, each ring listed in Table 6 may correspond to a given point or series of points on the topological profile of the phase ring structure. For example, FIG. 2B includes annotations (1), (3), (4), (8), (9), and (12), each of which may correspond to rings 1, 3, 4, 8, 9, and 12, respectively, in Table 6 above. As shown, ring 1 may correspond to a position where the phase ring structure transitions between a first inner sloping portion and a first outer sloping portion of the inner region. Ring 3 may correspond to a position where the phase ring structure transitions between the inner region and the outer region (i.e., a position where the outer edge of the inner region is adjacent to the inner edge of the outer region). Ring 4 may correspond to a position where the phase ring structure transitions between a second inner sloping portion and a first intermediate sloping portion. Ring 8 may correspond to a position where the phase ring structure transitions from a first intermediate sloping portion to a second intermediate sloping portion of the outer region. Ring 9 may correspond to a position where the phase ring structure transitions from a second intermediate sloping portion to a second outer sloping portion of the outer region. Ring 12 may correspond to the location where the phase ring structure of the lens transitions into the base curvature of the lens. Each ring not explicitly named above may be located within a given sloped portion of the phase ring structure. For example, ring 2 may be located between ring 1 and ring 3 in a first outer sloped portion of the phase ring structure. Rings 5, 6, and 7 may be located between ring 4 and ring 8 in a first intermediate sloped portion of the phase ring structure. Rings 10 and 11 may be located between ring 9 and ring 12 in a second outer sloped portion of the phase ring structure.

[0112] Example 7: MTF of an EDOF ophthalmic lens according to the seventh aspect of the present disclosure Fig. 10 shows the optical performance (MTF) of the EDOF ophthalmic lens with phase ring structure according to the seventh embodiment of the present disclosure. The MTF of Fig. 10 can correspond to the phase profile shown in Fig. 2B. The parameters A and D according to formula (IV) are various, as shown in Table 7 below.

[0113] Table 7: Variations of parameters A and D in the seventh aspect of the present disclosure TIFF2025501395000031.tif66128

[0114] Curve (1) shows the MTF with a 3 mm aperture and a measured resolution of 50 LP / mm. Curve (2) shows the MTF with a 2 mm aperture and a measured resolution of 50 LP / mm. Curve (3) shows the MTF with a 3 mm aperture and a measured resolution of 50 LP / mm in single focus mode. Curve (4) shows the MTF with a 2 mm aperture and a measured resolution of 50 LP / mm in single focus mode. Curves (1)-(4) in FIG. 10 are for an add power of approximately 3.0 D. TIFF2025501395000032.tif8128 shows focus at approximately 20.5D.

[0115] In some embodiments, each ring set forth in Table 7 may correspond to a given point or series of points on the topological profile of the topological ring structure. For example, FIG. 2B includes annotations (1), (3), (4), (8), (9), and (12), each of which may correspond to rings 1, 3, 4, 8, 9, and 12, respectively, of Table 7 above. The location of one or more rings from Table 7 in the topological profile of FIG. 2B may be substantially the same as the locations described above with respect to Example 6.

[0116] Example 8: MTF of a multifocal lens according to the first aspect of the present disclosure Figure 15A shows the optical performance (MTF) of a multifocal ophthalmic lens with a phase ring structure according to the first embodiment of the present disclosure. The MTF of Figure 15A can correspond to the phase profile shown in Figure 13A. The parameters A and D according to formula (IV) (above) are varied as shown in Table 8 below.

[0117] Table 8: Variations of parameters A and D in the first embodiment of the present disclosure TIFF2025501395000033.tif66128

[0118] Curve (1) shows the MTF with a 3 mm aperture and a measured resolution of 50 LP / mm. Curve (2) shows the MTF with a 2 mm aperture and a measured resolution of 50 LP / mm. Curve (3) shows the MTF with a 3 mm aperture and a measured resolution of 50 LP / mm in single focus mode. Curves (1)-(3) in FIG. 15A are for an add power of approximately 3.5D. TIFF2025501395000034.tif8128 shows focus at approximately 21.5D.

[0119] In some embodiments, each ring listed in Table 8 may correspond to a given point or series of points on the topological profile of the phase ring structure. For example, FIG. 13A includes annotations (1)-(3), (6), (7), (9), and (12), each of which may correspond to rings 1-3, 6, 7, 9, and 12, respectively, in Table 8 above. As shown, ring 1 may correspond to a position where the phase ring structure transitions between a first inner sloping portion and a first outer sloping portion of the inner region. Ring 2 may correspond to a position where the phase ring structure transitions between the inner region and the intermediate region (i.e., a position where the outer edge of the inner region is adjacent to the inner edge of the intermediate region). Ring 3 may correspond to a position where the phase ring structure transitions between a second inner sloping portion and a second outer sloping portion of the intermediate region. Ring 6 may correspond to a position where the phase ring structure transitions between the intermediate region and the outer region (i.e., a position where the outer edge of the intermediate region is adjacent to the inner edge of the outer region). Ring 7 may correspond to a location where the phase ring structure transitions from the third inner slope portion of the outer region to the intermediate slope portion. Ring 9 may correspond to a location where the phase ring structure transitions from the intermediate slope portion of the outer region to the third outer slope portion. Ring 12 may correspond to a location where the phase ring structure of the lens transitions to the base curvature of the lens. Each ring not explicitly listed above may be located within a given slope portion of the phase ring structure. For example, rings 4 and 5 may be located between rings 3 and 6 during the second outer slope portion of the phase ring structure. Ring 8 may be located between rings 7 and 9 during the intermediate slope portion of the phase ring structure. Rings 10 and 11 may be located between rings 9 and 12 during the third outer slope portion of the phase ring structure.

[0120] Example 9: MTF of a multifocal lens according to the second aspect of the present disclosure Fig. 15B shows the optical performance (MTF) of a multifocal ophthalmic lens with a phase ring structure according to the second embodiment of the present disclosure. The MTF of Fig. 15B can correspond to the phase profile shown in Fig. 13A. The parameters A and D according to formula (IV) (above) are varied as shown in Table 9 below.

[0121] Table 9: Variations of parameters A and D in the second embodiment of the present disclosure TIFF2025501395000035.tif66128

[0122] Curve (1) shows the MTF with a 3 mm aperture and a measured resolution of 50 LP / mm. Curve (2) shows the MTF with a 2 mm aperture and a measured resolution of 50 LP / mm. Curve (3) shows the MTF with a 3 mm aperture and a measured resolution of 50 LP / mm in single focus mode. Curves (1)-(3) in FIG. 15B are for an add power of approximately 3.5D. TIFF2025501395000036.tif8128 shows focus at approximately 21.5D.

[0123] In some embodiments, each ring set forth in Table 9 may correspond to a given point or series of points on the topological profile of the topological ring structure. For example, FIG. 13A includes annotations (1)-(3), (6), (7), (9), and (12), each of which may correspond to rings 1-3, 6, 7, 9, and 12, respectively, of Table 9 above. The locations of one or more rings from Table 9 in the topological profile of FIG. 13A may be substantially the same as those described above with respect to Example 8.

[0124] Example 10: MTF of a multifocal lens according to the fifth aspect of the present disclosure Fig. 15C shows the optical performance (MTF) of a multifocal ophthalmic lens with a phase ring structure according to the fifth embodiment of the present disclosure. The MTF of Fig. 15C can correspond to the phase profile shown in Fig. 13B. The parameters A and D according to formula (IV) (above) are varied as shown in Table 10 below.

[0125] Table 10: Variations of parameters A and D in the fifth aspect of the present disclosure TIFF2025501395000037.tif71128

[0126] Curve (1) shows the MTF with a 3 mm aperture and a measured resolution of 50 LP / mm. Curve (2) shows the MTF with a 2 mm aperture and a measured resolution of 50 LP / mm. Curve (3) shows the MTF with a 3 mm aperture and a measured resolution of 50 LP / mm in single focus mode. Curves (1)-(3) of FIG. 15C are for an add power of approximately 3.35D. TIFF2025501395000038.tif8128 shows focus at approximately 20.5D.

[0127] In some embodiments, each ring listed in Table 10 may correspond to a given point or series of points on the topological profile of the phase ring structure. For example, FIG. 13B includes annotations (1), (3), (4), (6), (7), (10), and (13), each of which may correspond to rings 1, 3, 4, 6, 7, 10, and 13, respectively, in Table 10 above. As shown, ring 1 may correspond to a position where the phase ring structure transitions between a first inner sloping portion and a first outer sloping portion of the inner region. Ring 3 may correspond to a position where the phase ring structure transitions between the inner region and the intermediate region (i.e., a position where the outer edge of the inner region is adjacent to the inner edge of the intermediate region). Ring 4 may correspond to a position where the phase ring structure transitions between a second inner sloping portion and a second outer sloping portion of the intermediate region. Ring 6 may correspond to a position where the phase ring structure transitions between the intermediate region and the outer region (i.e., a position where the outer edge of the intermediate region is adjacent to the inner edge of the outer region). Ring 7 may correspond to a location where the phase ring structure transitions from the third inner sloped portion of the outer region to the intermediate sloped portion. Ring 10 may correspond to a location where the phase ring structure transitions from the intermediate sloped portion of the outer region to the third outer sloped portion. Ring 13 may correspond to a location where the phase ring structure of the lens transitions to the base curvature of the lens. Each ring not explicitly listed above may be located within a given sloped portion of the phase ring structure. For example, ring 2 may be located between ring 1 and ring 3 in the first outer sloped portion of the phase ring structure. Ring 5 may be located between ring 4 and ring 6 in the second outer sloped portion of the phase ring structure. Rings 8 and 9 may be located between ring 7 and ring 10 in the intermediate sloped portion of the phase ring structure. Rings 11 and 12 may be located in the third outer sloped portion of the phase ring structure.

[0128] Unless otherwise specified, all technical terms, notations, and other scientific or technical terms or terminology used herein are intended to have the same meaning as commonly understood by one of ordinary skill in the art to which the claimed subject matter pertains. In some cases, terms having a commonly understood meaning are defined herein for clarity and / or ease of reference, but the inclusion of such definitions herein should not necessarily be construed as representing a substantial difference from the definition commonly understood in the art.

[0129] As used herein, the singular forms "a," "an," and "the" are intended to include the plural forms unless the context clearly indicates otherwise. Also, as used herein, the word "and / or" is understood to refer to and include any possible combination of one or more of the associated listed items. Furthermore, as used herein, the words "includes," "including," "comprises," and / or "comprising" are understood to specify the presence of stated features, integers, steps, operations, elements, components, and / or units, but not to preclude the presence or addition of one or more other features, integers, steps, operations, elements, components, units, and / or groups thereof.

[0130] The disclosed numerical ranges inherently support any range or value within the disclosed numerical ranges (including the endpoints), since the disclosure can be practiced throughout the disclosed numerical ranges, even if an exact range limitation is not literally recited in the specification.

[0131] The foregoing detailed description has been described with reference to specific embodiments for explanatory purposes. However, the above illustrative description is not intended to be exhaustive or to limit the invention to the precise form disclosed. Numerous modifications and variations are possible in light of the above teachings. The embodiments have been chosen and described in order to best explain the principles of the technology and its practical application so that others skilled in the art may best utilize the technology and various embodiments with various modifications as appropriate for the specific applications envisioned.

[0132] Although the present disclosure and examples have been fully described with reference to the accompanying drawings, it is noted that various modifications and variations will become apparent to those skilled in the art, and such modifications and variations are understood to be included within the scope of the disclosure and examples as defined by the claims.

[0133] Aspects Aspect 1 An ophthalmic lens comprising a lens body, the lens body comprising (a) a first aspheric surface; and (b) Base curvature (Z asp ) and the phase profile Φ (n) (r) A phase ring structure (Z phase ) and a second aspheric surface (Z total ) thereby generating a far focus (f0) and an extended focus (f1); Ophthalmic lenses.

[0134] Aspect 2 The ophthalmic lens of embodiment 1, wherein the first aspheric surface is a front surface.

[0135] Aspect 3 The ophthalmic lens of embodiment 1, wherein the second aspheric surface is a posterior surface.

[0136] Aspect 4 The ophthalmic lens of embodiment 1, wherein the first aspheric surface includes a toric component.

[0137] Aspect 5 The height profile of the base curve (Z asp )but As shown by TIFF2025501395000039.tif14128, Here, Z asp is the height profile of the aspheric structure, r is the radial distance in millimeters from the center of the lens, c is the curvature, k is the conic constant, and A i is a higher-order correction term, 2. The ophthalmic lens of embodiment 1.

[0138] Aspect 6 The second aspheric surface (Z total )but Z total (r)=Z asp (r)+Z phase (r) 2. The ophthalmic lens of embodiment 1, as represented by:

[0139] Aspect 7 Phase profile Φ (n) (r) As shown by TIFF2025501395000040.tif10128, where r is the radial distance of the lens in millimeters, and r n is the radius of the nth zone, and r n+1 is the radius of the (n+1)th zone, f(r) is the phase function base profile which may be a linear, parabolic, sinusoidal or polynomial function, and A (n) is the ratio of the phase function base profiles, D (n) is the phase shift of the phase function base profile, 2. The ophthalmic lens of embodiment 1.

[0140] Aspect 8 The radius of the nth zone (r n )but As shown by TIFF2025501395000041.tif6128, r n is the radius of the nth zone, λ is the design wavelength, and f is the reciprocal of the add power. 8. The ophthalmic lens of embodiment 7.

[0141] Aspect 9 A height profile of the phase ring structure related to the base curvature of the ophthalmic lens: TIFF2025501395000042.tif10128 where Z phase is the height profile of the phase ring structure, λ is the design wavelength, and Φ (n) (r) is the phase profile, n1 is the refractive index of the ophthalmic lens material, and n0 is the refractive index of the medium covering said ophthalmic lens; 2. The ophthalmic lens of embodiment 1.

[0142] Aspect 10 Phase profile Φ (n) (r) 0≦|Φ (n) (r)|≦6π 2. The ophthalmic lens of embodiment 1, wherein

[0143] Aspect 11 The far focus (f0) and the extended focus (f1) An ophthalmic lens of embodiment 1, which is in the range of TIFF2025501395000043.tif10128.

[0144] Aspect 12 The ophthalmic lens of embodiment 1, which is an intraocular lens (IOL) or a contact lens.

[0145] Aspect 13 The ophthalmic lens of embodiment 1, further comprising a pair of haptics extending outwardly from said lens body.

[0146] Aspect 14a Implanting an ophthalmic lens including the lens body into the subject's eye. Including, The lens body (a) Base curve, and (b) Phase ring structure Including, A method of treating an ophthalmic disease or disorder in a subject.

[0147] Aspect 14b Implanting an ophthalmic lens including the lens body into the subject's eye. Including, The lens body (a) a first aspheric surface; and (b) a second aspheric surface including a base curve and an optical phase ring structure; Including, A method of treating an ophthalmic disease or disorder in a subject.

[0148] Aspect 15 The method of embodiment 14, wherein said ophthalmic disease or disorder is selected from the group consisting of cataracts and presbyopia.

[0149] Aspect 16 The method of embodiment 14, wherein said ophthalmic lens is an IOL or a contact lens.

[0150] Aspect 17 17. The method of embodiment 16, wherein the IOL further includes a pair of haptics extending outwardly from the lens body.

[0151] Aspect 18 The method of embodiment 16, wherein the IOL is implanted in the capsular bag of the subject's eye.

[0152] Aspect 19 (a) fabricating a first aspheric surface, optionally including a toric component; and (b) fabricating a second aspheric surface including a base curve and a phase ring structure; thereby producing a far focus (f0) and an extended focus (f1).

[0153] Aspect 20 performing an in situ image quality analysis to ensure that the performance of said ophthalmic lens meets predetermined quality standards. The method of embodiment 19, further comprising:

[0154] Aspect 21 1. An ophthalmic lens comprising a lens body, The lens body, A first aspheric surface, and A second aspheric surface including a base curvature and a phase ring structure. Including, the phase ring structure includes an inner region and an outer region; the inner region includes a first phase ring surface having a first curvature; the outer region includes a second phase ring surface having a second curvature; an outer edge of the inner region adjacent to an inner edge of the outer region; Refraction of light passing through the inner and outer regions causes constructive interference that produces a far focus (f0) and an extended focus (f1). Ophthalmic lenses.

[0155] Aspect 22 22. The ophthalmic lens of embodiment 21, wherein a radius of the inner region of the phase ring structure extending from an optical axis of the ophthalmic lens to an outer edge of the inner region is greater than 0 mm and less than or equal to 0.70 mm.

[0156] Aspect 23 22. The ophthalmic lens of embodiment 21, wherein a radius of the outer region of the phase ring structure, extending from an optical axis of the ophthalmic lens to an outer edge of the outer region, is greater than 0 mm and less than or equal to 1.30 mm.

[0157] Aspect 24 22. The ophthalmic lens of embodiment 21, wherein the first curvature of the first phase ring surface includes a first inner sloping portion inclined at a first angle relative to an optical axis of the ophthalmic lens and a first outer sloping portion inclined at a second angle relative to the optical axis.

[0158] Aspect 25 25. The ophthalmic lens of embodiment 24, wherein the first inner sloped portion and the first outer sloped portion are both monotonically sloped with respect to the optical axis.

[0159] Aspect 26 22. The ophthalmic lens of embodiment 21, wherein the second curvature of the second phase ring surface includes a second inner sloping portion inclined at a third angle relative to an optical axis of the ophthalmic lens, a middle sloping portion inclined at a fourth angle relative to the optical axis, and a second outer sloping portion inclined at a fifth angle relative to the optical axis.

[0160] Aspect 27 27. The ophthalmic lens of embodiment 26, wherein the intermediate sloped portion and the second outer sloped portion are both monotonically sloped with respect to the optical axis, and the intermediate portion and the second inner sloped portion are both non-monotonically sloped with respect to the second outer sloped portion.

[0161] Aspect 28 22. The ophthalmic lens of embodiment 21, wherein said first aspheric surface is a front surface of said lens body.

[0162] Aspect 29 22. The ophthalmic lens of embodiment 21, wherein the second aspheric surface is a posterior surface of the lens body.

[0163] Aspect 30 22. The ophthalmic lens of embodiment 21, wherein the first aspheric surface includes a toric component.

[0164] Aspect 31 The height profile of the base curvature (Z asp )but As shown by TIFF2025501395000044.tif14128, where r is the radial distance in millimeters from the center of the lens, c is the lens curvature, k is the conic constant, and A i is a higher-order correction term, 22. The ophthalmic lens of embodiment 21.

[0165] Aspect 32 The height profile of the lens body (Z total )but Z total (r)=Z asp (r)+Z phase (r) 22. The ophthalmic lens of embodiment 21, as represented by:

[0166] Aspect 33 Phase profile (Φ (n) (r)) As shown by TIFF2025501395000045.tif7128, where r is the radial distance in millimeters from the center of the lens, and r n is the outer radius of the nth zone, and r n+1 is the outer radius of the (n+1)th zone, f(r) is the phase function base profile which may be a linear, parabolic, sinusoidal or polynomial function, and A (n) is the ratio of the phase function base profiles, and D (n) is the phase shift of the phase function base profile, 22. The ophthalmic lens of embodiment 21.

[0167] Aspect 34 The outer radius (r n )but As shown by TIFF2025501395000046.tif6128, where λ is the design wavelength and f is the reciprocal of the add power. 34. The ophthalmic lens of embodiment 33.

[0168] Aspect 35 The height ratio of the inner region to the outer region of the phase ring structure is 0≦Φ (n) (r out )-Φ (n) (r in )≦4π 34. The ophthalmic lens of embodiment 33, as shown by:

[0169] Aspect 36 The height profile (Z phase ) is related to the base curvature of the ophthalmic lens: TIFF2025501395000047.tif10128 where λ is the design wavelength and Φ (n)(r) is the phase profile, n1 is the refractive index of the material of the ophthalmic lens, and n0 is the refractive index of the medium covering the ophthalmic lens; 22. The ophthalmic lens of embodiment 21.

[0170] Aspect 37 The phase profile (Φ (n) (r)) 0≦|Φ (n) (r)|≦8π 22. The ophthalmic lens of embodiment 21,

[0171] Aspect 38 The far focus (f0) and the extended focus (f1) are expressed by the following formula: Defined by TIFF2025501395000048.tif10128, During the ceremony, TIFF2025501395000049.tif8128 is the addition power, 22. The ophthalmic lens of embodiment 21.

[0172] Aspect 39 22. The ophthalmic lens of embodiment 21, which is an intraocular lens or a contact lens.

[0173] Aspect 40 22. The ophthalmic lens of embodiment 21, comprising a pair of haptics extending outwardly from the lens body.

[0174] Aspect 41 Implanting an ophthalmic lens including the lens body into the subject's eye. Including, The lens body, A first aspheric surface, and A second aspheric surface including a base curvature and a phase ring structure. Including, the phase ring structure includes an inner region and an outer region; the inner region includes a first phase ring surface having a first curvature; the outer region includes a second phase ring surface having a second curvature; an outer edge of the inner region adjacent to an inner edge of the outer region; refraction of light passing through the inner and outer regions causes constructive interference that produces a far focus and an extended focus; A method of treating an ophthalmic disease or disorder in a subject.

[0175] Aspect 42 The method of embodiment 41, wherein said ophthalmic disease or disorder is selected from the group consisting of cataracts and presbyopia.

[0176] Aspect 43 The method of embodiment 41, wherein the ophthalmic lens is an intraocular lens or a contact lens.

[0177] Aspect 44 44. The method of embodiment 43, wherein the intraocular lens includes a pair of haptics extending outwardly from the lens body.

[0178] Aspect 45 The method of embodiment 43, wherein the intraocular lens is implanted in the lens capsule of the eye of the subject.

[0179] Aspect 46 fabricating a first aspheric surface; fabricating a second aspheric surface including a base curvature; and Creating a phase ring structure on the second aspheric surface. Including, the phase ring structure includes an inner region and an outer region; the inner region includes a first phase ring surface having a first curvature; the outer region includes a second phase ring surface having a second curvature; an outer edge of the inner region adjacent to an inner edge of the outer region; refraction of light passing through the inner and outer regions causes constructive interference that produces a far focus and an extended focus; A method for manufacturing an ophthalmic lens.

[0180] Aspect 47 47. The method of embodiment 46, comprising performing an in situ image quality analysis to determine whether the performance of said ophthalmic lens meets predetermined quality standards.

[0181] Aspect 48 A first aspheric surface, and A second aspheric surface including a base curvature and a phase ring structure. Including the lens body Including, the phase ring structure includes an inner region, a middle region, and an outer region; the inner region includes a first phase ring surface having a first curvature; the intermediate region includes a second phase ring surface having a second curvature; the outer region includes a third phase ring surface having a third curvature; an outer edge of the inner region adjacent to an inner edge of the intermediate region; an outer edge of the intermediate region adjacent to an inner edge of the outer region; refraction of light passing through the inner region, the intermediate region and the outer region creates constructive interference that produces a near focus and a far focus; Ophthalmic lenses.

[0182] Aspect 49 49. The ophthalmic lens of embodiment 48, wherein a radius of the inner region of the phase ring structure extending from an optical axis of the ophthalmic lens to an outer edge of the inner region is greater than 0 mm and less than or equal to 0.70 mm.

[0183] Aspect 50 49. The ophthalmic lens of embodiment 48, wherein a radius of the intermediate region of the phase ring structure extending from an optical axis of the ophthalmic lens to the outer edge of the intermediate region is greater than 0 mm and less than or equal to 1.30 mm.

[0184] Aspect 51 49. The ophthalmic lens of embodiment 48, wherein a radius of the outer region of the phase ring structure extending from an optical axis of the ophthalmic lens to an outer edge of the outer region is greater than 0 mm and less than or equal to 1.30 mm.

[0185] Aspect 52 49. The ophthalmic lens of embodiment 48, wherein the first curvature of the first phase ring surface includes a first inner sloping portion inclined at a first angle relative to an optical axis of the ophthalmic lens and a first outer sloping portion inclined at a second angle relative to the optical axis.

[0186] Aspect 53 53. The ophthalmic lens of embodiment 52, wherein the first inner sloped portion and the first outer sloped portion are both monotonically sloped with respect to the optical axis.

[0187] Aspect 54 49. The ophthalmic lens of embodiment 48, wherein the second curvature of the second phase ring surface includes a second inner sloping portion inclined at a third angle relative to an optical axis of the ophthalmic lens and a second outer sloping portion inclined at a fourth angle relative to the optical axis.

[0188] Aspect 55 55. The ophthalmic lens of embodiment 54, wherein both the second inner sloped portion and the second outer sloped portion are not monotonically sloped relative to the optical axis.

[0189] Aspect 56 49. The ophthalmic lens of embodiment 48, wherein the third curvature of the third phase ring surface includes a third inner sloping portion inclined at a fifth angle relative to an optical axis of the ophthalmic lens and a third outer sloping portion inclined at a sixth angle relative to the optical axis.

[0190] Aspect 57 57. The ophthalmic lens of embodiment 56, wherein both the third inner sloped portion and the third outer sloped portion are not monotonically sloped relative to the optical axis.

[0191] Aspect 58 58. The ophthalmic lens of embodiment 57, wherein the first aspheric surface is the anterior surface of the lens body.

[0192] Aspect 59 58. The ophthalmic lens of embodiment 57, wherein the second aspheric surface is a posterior surface of the lens body.

[0193] Aspect 60 58. The ophthalmic lens of embodiment 57, wherein the first aspheric surface includes a toric component.

[0194] Aspect 61 Implanting an ophthalmic lens including the lens body into the subject's eye. Including, The lens body, A first aspheric surface, and A second aspheric surface including a base curvature and a phase ring structure. Including, the phase ring structure includes an inner region, a middle region, and an outer region; the inner region includes a first phase ring surface having a first curvature; the intermediate region includes a second phase ring surface having a second curvature; the outer region includes a third phase ring surface having a third curvature; an outer edge of the inner region adjacent to an inner edge of the intermediate region; an outer edge of the intermediate region adjacent to an inner edge of the outer region; refraction of light passing through the inner region, the intermediate region and the outer region creates constructive interference that produces a near focus and a far focus; A method of treating an ophthalmic disease or disorder in a subject.

[0195] Aspect 62 62. The method of embodiment 61, wherein said ophthalmic disease or disorder is selected from the group consisting of cataracts and presbyopia.

[0196] Aspect 63 The method of embodiment 61, wherein the ophthalmic lens is an intraocular lens or a contact lens.

[0197] Aspect 64 The method of embodiment 63, wherein the intraocular lens includes a pair of haptics extending outwardly from the lens body.

[0198] Aspect 65 The method of embodiment 63, wherein the intraocular lens is implanted in the lens capsule of the eye of the subject.

[0199] Aspect 66 fabricating a first aspheric surface; fabricating a second aspheric surface including a base curvature; and Creating a phase ring structure on the second aspheric surface. Including, the phase ring structure includes an inner region, a middle region, and an outer region; the inner region includes a first phase ring surface having a first curvature; the intermediate region includes a second phase ring surface having a second curvature; the outer region includes a third phase ring surface having a third curvature; an outer edge of the inner region adjacent to an inner edge of the intermediate region; an outer edge of the intermediate region adjacent to an inner edge of the outer region; refraction of light passing through the inner region, the intermediate region and the outer region creates constructive interference that produces a near focus and a far focus; A method for manufacturing an ophthalmic lens.

[0200] Aspect 67 67. The method of embodiment 66, comprising performing an in situ image quality analysis to determine whether the performance of the ophthalmic lens meets predetermined quality standards.

[0201] Aspect 68 A first aspheric surface, and a second aspheric surface including a first base curvature and a first optical phase ring structure; a first lens body including Including, the first optical phase ring structure includes a first inner region and a first outer region; the first inner region includes a first phase ring surface; the first outer region includes a second phase ring surface; A first ophthalmic lens, and a third aspheric surface, and a fourth aspheric surface including a second base curvature and a second optical phase ring structure; A second lens body including Including, the second optical phase ring structure includes a second inner region, a middle region, and a second outer region; the second inner region includes a third phase ring surface; the intermediate region includes a fourth phase ring surface; the second outer region includes a fifth phase ring surface; Secondary Ophthalmic Lenses Including, refraction of light passing through the first inner region and the outer region of the first ophthalmic lens creates a first constructive interference, and refraction of light passing through the second inner region, the intermediate region and the second outer region creates a second constructive interference, thereby collectively producing a near focus, a far focus and an extended focus. A set of ophthalmic lenses.

Claims

1. A first aspheric surface, and A second aspheric surface including a base curvature and a phase ring structure. Including the lens body Including, the phase ring structure includes an inner region and an outer region; the inner region includes a first phase ring surface having a first curvature; the outer region includes a second phase ring surface having a second curvature; an outer edge of the inner region adjacent to an inner edge of the outer region; The refraction of light passing through the inner and outer regions is called the far focus (f 0 ) and extended focus (f 1 ) resulting in constructive interference that creates Ophthalmic lenses.

2. 2. The ophthalmic lens of claim 1, wherein a radius of the inner region of the phase ring structure, extending from an optical axis of the ophthalmic lens to the outer edge of the inner region, is greater than 0 mm and less than or equal to 0.70 mm.

3. 3. The ophthalmic lens of claim 1, wherein the radius of the outer region of the phase ring structure, extending from the optical axis of the ophthalmic lens to the outer edge of the outer region, is greater than 0 mm and less than or equal to 1.30 mm.

4. 4. The ophthalmic lens of claim 1, wherein the first curvature of the first phase ring surface comprises a first inner sloping portion inclined at a first angle relative to an optical axis of the ophthalmic lens and a first outer sloping portion inclined at a second angle relative to the optical axis.

5. The ophthalmic lens of claim 4 , wherein the first inner sloped portion and the first outer sloped portion are both monotonically sloped with respect to the optical axis.

6. 6. The ophthalmic lens of claim 1, wherein the second curvature of the second phase ring surface comprises a second inner sloping portion inclined at a third angle relative to an optical axis of the ophthalmic lens, a middle sloping portion inclined at a fourth angle relative to the optical axis, and a second outer sloping portion inclined at a fifth angle relative to the optical axis.

7. 7. The ophthalmic lens of claim 6, wherein the intermediate sloped portion and the second outer sloped portion are both monotonically sloped with respect to the optical axis, and the intermediate portion and the second inner sloped portion are both non-monotonically sloped with respect to the second outer sloped portion.

8. The ophthalmic lens of any one of claims 1 to 7, wherein the first aspheric surface is a front surface of the lens body.

9. The ophthalmic lens of any one of claims 1 to 8, wherein the second aspheric surface is a rear surface of the lens body.

10. The ophthalmic lens of any one of claims 1 to 9, wherein the first aspheric surface includes a toric component.

11. 2. The base curvature height profile (Z asp )but is shown by where r is the radial distance in millimeters from the center of the lens, c is the lens curvature, k is the conic constant, and A i is a higher-order correction term, An ophthalmic lens according to any one of claims 1 to 10.

12. The height profile of the lens body (Z total )but Z total (r)=Z asp (r)+Z phase (r) The ophthalmic lens according to any one of claims 1 to 11, wherein

13. Phase profile (Φ (n) (r) is shown by where r is the radial distance in millimeters from the center of the lens, and r n is the radius of the nth zone, and r n+1 is the radius of the (n+1)th zone, f(r) is the phase function base profile which may be a linear, parabolic, sinusoidal or polynomial function, and A (n) is the ratio of the phase function base profiles, and D (n) is the phase shift of the phase function base profile, An ophthalmic lens according to any one of claims 1 to 12.

14. The radius (r n )but is shown by where λ is the design wavelength and f is the reciprocal of the add power.

14. The ophthalmic lens of claim 13.

15. The height ratio of the inner region to the outer region of the phase ring structure is 0≦Φ (n) (r out )-Φ (n) (r in )≦4π 15. The ophthalmic lens of claim 13 or 14, wherein:

16. The height profile (Z phase ) is related to the base curvature of the ophthalmic lens: where λ is the design wavelength and Φ (n) (r) is the phase profile, and n 1 is the refractive index of the material of the ophthalmic lens, n 0 is the refractive index of the medium covering the ophthalmic lens, An ophthalmic lens according to any one of claims 1 to 15.

17. The phase profile (Φ (n) (r) 0≦|Φ (n) (r)|≦8π 2. The ophthalmic lens of claim 1,

18. The far focus (f 0 ) and the expanded focus (f 1 ) is expressed as follows: is defined by During the ceremony, is the addition power, An ophthalmic lens according to any one of claims 1 to 17.

19. The ophthalmic lens of any one of claims 1 to 18, which is an intraocular lens or a contact lens.

20. The ophthalmic lens of any one of claims 1 to 19, comprising a pair of haptics extending outwardly from the lens body.

21. Implanting an ophthalmic lens including the lens body into the subject's eye. Including, The lens body, A first aspheric surface, and A second aspheric surface including a base curvature and a phase ring structure. Including, the phase ring structure includes an inner region and an outer region; the inner region includes a first phase ring surface having a first curvature; the outer region includes a second phase ring surface having a second curvature; an outer edge of the inner region adjacent to an inner edge of the outer region; refraction of light passing through the inner and outer regions causes constructive interference that produces a far focus and an extended focus; A method of treating an ophthalmic disease or disorder in a subject.

22. 22. The method of claim 21, wherein the ophthalmic disease or disorder is selected from the group consisting of cataracts and presbyopia.

23. 23. The method of claim 21 or 22, wherein the ophthalmic lens is an intraocular lens or a contact lens.

24. The method of claim 23 , wherein the intraocular lens includes a pair of haptics extending outwardly from the lens body.

25. 25. The method of claim 23 or 24, wherein the intraocular lens is implanted in the capsular bag of the eye of the subject.

26. fabricating a first aspheric surface; fabricating a second aspheric surface including a base curvature; and Creating a phase ring structure on the second aspheric surface. Including, the phase ring structure includes an inner region and an outer region; the inner region includes a first phase ring surface having a first curvature; the outer region includes a second phase ring surface having a second curvature; an outer edge of the inner region adjacent to an inner edge of the outer region; refraction of light passing through the inner and outer regions causes constructive interference that produces a far focus and an extended focus; A method for manufacturing an ophthalmic lens.

27. 27. The method of claim 26, comprising performing an in situ image quality analysis to determine whether the performance of the ophthalmic lens meets predetermined quality standards.

28. A first aspheric surface, and A second aspheric surface including a base curvature and a phase ring structure. Including the lens body Including, the phase ring structure includes an inner region, a middle region, and an outer region; the inner region includes a first phase ring surface having a first curvature; the intermediate region includes a second phase ring surface having a second curvature; the outer region includes a third phase ring surface having a third curvature; an outer edge of the inner region adjacent to an inner edge of the intermediate region; an outer edge of the intermediate region adjacent to an inner edge of the outer region; refraction of light passing through the inner region, the intermediate region and the outer region creates constructive interference that produces a near focus and a far focus; Ophthalmic lenses.

29. 30. The ophthalmic lens of claim 28, wherein a radius of the inner region of the phase ring structure, extending from an optical axis of the ophthalmic lens to the outer edge of the inner region, is greater than 0 mm and less than or equal to 0.70 mm.

30. 30. The ophthalmic lens of claim 28 or 29, wherein a radius of the intermediate region of the phase ring structure, extending from an optical axis of the ophthalmic lens to the outer edge of the intermediate region, is greater than 0 mm and less than or equal to 1.30 mm.

31. The ophthalmic lens of any one of claims 28 to 30, wherein a radius of the outer region of the phase ring structure, extending from an optical axis of the ophthalmic lens to an outer edge of the outer region, is greater than 0 mm and less than or equal to 1.30 mm.

32. 32. The ophthalmic lens of any one of claims 28 to 31, wherein the first curvature of the first phase ring surface comprises a first inner sloping portion inclined at a first angle relative to an optical axis of the ophthalmic lens and a first outer sloping portion inclined at a second angle relative to the optical axis.

33. 33. The ophthalmic lens of claim 32, wherein the first inner sloped portion and the first outer sloped portion are both monotonically sloped with respect to the optical axis.

34. 34. The ophthalmic lens of any one of claims 28 to 33, wherein the second curvature of the second phase ring surface comprises a second inner sloping portion inclined at a third angle relative to an optical axis of the ophthalmic lens and a second outer sloping portion inclined at a fourth angle relative to the optical axis.

35. 35. The ophthalmic lens of claim 34, wherein both the second inner sloped portion and the second outer sloped portion are not monotonically sloped with respect to the optical axis.

36. 36. The ophthalmic lens of any one of claims 28 to 35, wherein the third curvature of the third phase ring surface comprises a third inner sloping portion inclined at a fifth angle relative to an optical axis of the ophthalmic lens, and a third outer sloping portion inclined at a sixth angle relative to the optical axis.

37. 37. The ophthalmic lens of claim 36, wherein both the third inner sloped portion and the third outer sloped portion are not monotonically sloped with respect to the optical axis.

38. The ophthalmic lens of any one of claims 28 to 37, wherein the first aspheric surface is a front surface of the lens body.

39. The ophthalmic lens of any one of claims 28 to 38, wherein the second aspheric surface is a rear surface of the lens body.

40. The ophthalmic lens of any one of claims 28 to 39, wherein the first aspheric surface includes a toric component.

41. Implanting an ophthalmic lens including the lens body into the subject's eye. Including, The lens body, A first aspheric surface, and A second aspheric surface including a base curvature and a phase ring structure. Including, the phase ring structure includes an inner region, a middle region, and an outer region; the inner region includes a first phase ring surface having a first curvature; the intermediate region includes a second phase ring surface having a second curvature; the outer region includes a third phase ring surface having a third curvature; an outer edge of the inner region adjacent to an inner edge of the intermediate region; an outer edge of the intermediate region adjacent to an inner edge of the outer region; refraction of light passing through the inner region, the intermediate region and the outer region creates constructive interference that produces a near focus and a far focus; A method of treating an ophthalmic disease or disorder in a subject.

42. 42. The method of claim 41, wherein the ophthalmic disease or disorder is selected from the group consisting of cataracts and presbyopia.

43. 43. The method of claim 41 or 42, wherein the ophthalmic lens is an intraocular lens or a contact lens.

44. 44. The method of claim 43, wherein the intraocular lens includes a pair of haptics extending outwardly from the lens body.

45. 45. The method of claim 43 or 44, wherein the intraocular lens is implanted in the lens capsule of the eye of the subject.

46. fabricating a first aspheric surface; fabricating a second aspheric surface including a base curvature; and Creating a phase ring structure on the second aspheric surface. Including, the phase ring structure includes an inner region, a middle region, and an outer region; the inner region includes a first phase ring surface having a first curvature; the intermediate region includes a second phase ring surface having a second curvature; the outer region includes a third phase ring surface having a third curvature; an outer edge of the inner region adjacent to an inner edge of the intermediate region; an outer edge of the intermediate region adjacent to an inner edge of the outer region; refraction of light passing through the inner region, the intermediate region and the outer region creates constructive interference that produces a near focus and a far focus; A method for manufacturing an ophthalmic lens.

47. 47. The method of claim 46, comprising performing an in situ image quality analysis to determine whether the performance of the ophthalmic lens meets predetermined quality standards.

48. A first aspheric surface, and a second aspheric surface including a first base curvature and a first optical phase ring structure; a first lens body including Including, the first optical phase ring structure includes a first inner region and a first outer region; the first inner region includes a first phase ring surface; the first outer region includes a second phase ring surface; A first ophthalmic lens, and a third aspheric surface, and a fourth aspheric surface including a second base curvature and a second optical phase ring structure; A second lens body including Including, the second optical phase ring structure includes a second inner region, a middle region, and a second outer region; the second inner region includes a third phase ring surface; the intermediate region includes a fourth phase ring surface; the second outer region includes a fifth phase ring surface; Secondary Ophthalmic Lenses Including, refraction of light passing through the first inner region and the outer region of the first ophthalmic lens creates a first constructive interference, and refraction of light passing through the second inner region, the intermediate region and the second outer region creates a second constructive interference, thereby collectively producing a near focus, a far focus and an extended focus. A set of ophthalmic lenses.

Images