Herbicidal composition containing 3-(2-chloro-4-fluoro-5-(3-methyl-2,6-dioxo-4-trifluoromethyl-3,6-dihydropyrimidin-1(2H)-yl)phenyl)-5-methyl-4,5-dihydroisoxazole-5-carboxylic acid ethyl ester and glufosinate-P and use thereof

Abstract

The present invention relates to the technical field of agrochemicals, specifically to a herbicidal composition containing 3-(2-chloro-4-fluoro-5-(3-methyl-2,6-dioxo-4-trifluoromethyl-3,6-dihydropyrimidin-1(2H)-yl)phenyl)-5-methyl-4,5-dihydroisoxazole-5-carboxylic acid ethyl ester and glufosinate-P and its use, the production raw material of which includes at least 3-(2-chloro-4-fluoro-5-(3-methyl-2,6-dioxo-4-trifluoromethyl-3,6-dihydropyrimidin-1(2H)-yl)phenyl)-5-methyl-4,5-dihydroisoxazole-5-carboxylic acid ethyl ester and glufosinate-P. The formulation of the herbicidal composition is at least one of a microemulsion, an emulsion, an oil suspension, a granule, a wettable powder, and a wettable powder. By combining 3-(2-chloro-4-fluoro-5-(3-methyl-2,6-dioxo-4-trifluoromethyl-3,6-dihydropyrimidin-1(2H)-yl)phenyl)-5-methyl-4,5-dihydroisoxazole-5-carboxylic acid ethyl ester with glufosinate-P, the herbicidal spectrum is expanded, the herbicidal effect is improved, it has fast-acting effect, long duration of action, can delay herbicide resistance, thorough weed control, low residual, low toxicity, high safety and environmental friendliness, and has excellent control effect on weeds in non-cultivated land.

Description

[Technical field]

[0001] The present invention relates to the technical field of agrochemicals, in particular to a herbicidal composition containing 3-(2-chloro-4-fluoro-5-(3-methyl-2,6-dioxo-4-trifluoromethyl-3,6-dihydropyrimidin-1(2H)-yl)phenyl)-5-methyl-4,5-dihydroisoxazole-5-carboxylic acid ethyl ester and glufosinate-P and its use. [Background technology]

[0002] In practical applications, herbicides are indispensable. However, a single herbicidal active ingredient may lead to the development of weed resistance, and its herbicidal spectrum is not broad enough. In addition, the performance stability of a single active ingredient under high and low temperature conditions is insufficient, resulting in limited applications. 3-(2-chloro-4-fluoro-5-(3-methyl-2,6-dioxo-4-trifluoromethyl-3,6-dihydropyrimidin-1(2H)-yl)phenyl)-5-methyl-4,5-dihydroisoxazole-5-carboxylic acid ethyl ester is a patented compound of Jiangshan Noka Co., Ltd. It is a non-selective contact herbicide that inhibits protoporphyrin oxidase (PPO) activity to kill weeds, and has a control effect on various weeds, especially excellent control effect on glyphosate-resistant weeds. Glufosinate-P is a phosphonic acid herbicide and a glutamine synthesis inhibitor. Glufosinate-P is suitable for weed control in non-cultivated land because after application, it disrupts the ammonium metabolism in the plant body, causing ammonium ions, a cytotoxic substance, to accumulate in the plant body and inhibiting photosynthesis.

[0003] When glufosinate-P is used alone, there are certain limitations. For example, a Chinese patent application (publication number: CN105660688A) discloses a soluble formulation of glufosinate-P and a method for preparing the same. Specifically, glufosinate-P is used as the active ingredient, and a surfactant and a filler are added to the formulation to prepare a soluble formulation, which has been put to practical use. However, due to the lack of herbicidal effect and broad spectrum, the scope of its use is limited. In order to solve the problem of the insufficient efficacy of a single agent, a Chinese patent application (publication number: CN112741102A) disclosed a glufosinate-P herbicide. By combining glufosinate-P with bromoxynil and / or chlorimuron-ethyl, the herbicidal spectrum has been expanded to a certain extent, but the stability of the system of the composition prepared in different formulations affects the exertion of efficacy and the amount of pesticide used, which has a certain impact on the environment and economy.

[0004] Considering this problem of difficult to control in the field, the present invention provides a herbicidal composition comprising 3-(2-chloro-4-fluoro-5-(3-methyl-2,6-dioxo-4-trifluoromethyl-3,6-dihydropyrimidin-1(2H)-yl)phenyl)-5-methyl-4,5-dihydroisoxazole-5-carboxylic acid ethyl ester and glufosinate-P. Summary of the Invention [Problem to be solved by the invention]

[0005] In order to solve the above problems, a herbicidal composition containing 3-(2-chloro-4-fluoro-5-(3-methyl-2,6-dioxo-4-trifluoromethyl-3,6-dihydropyrimidin-1(2H)-yl)phenyl)-5-methyl-4,5-dihydroisoxazole-5-carboxylic acid ethyl ester and glufosinate-P and use thereof are provided. By combining 3-(2-chloro-4-fluoro-5-(3-methyl-2,6-dioxo-4-trifluoromethyl-3,6-dihydropyrimidin-1(2H)-yl)phenyl)-5-methyl-4,5-dihydroisoxazole-5-carboxylic acid ethyl ester with glufosinate-P, the herbicidal spectrum is expanded, the herbicidal effect is improved, it has fast-acting effect, long duration of action, can delay herbicide resistance, thorough weed control, low residual, low toxicity, high safety and environmental friendliness, and has excellent control effect on weeds in non-cultivated land. [Means for solving the problem]

[0006] In one aspect of the present invention, there is provided a herbicidal composition containing 3-(2-chloro-4-fluoro-5-(3-methyl-2,6-dioxo-4-trifluoromethyl-3,6-dihydropyrimidin-1(2H)-yl)phenyl)-5-methyl-4,5-dihydroisoxazole-5-carboxylic acid ethyl ester and glufosinate-P, wherein the raw materials for producing the herbicidal composition contain at least 3-(2-chloro-4-fluoro-5-(3-methyl-2,6-dioxo-4-trifluoromethyl-3,6-dihydropyrimidin-1(2H)-yl)phenyl)-5-methyl-4,5-dihydroisoxazole-5-carboxylic acid ethyl ester and glufosinate-P, and the formulation of the herbicidal composition is at least one of a microemulsion, an emulsion, an oil-based suspension, a granule, a wettable powder, and a water dispersible granule.

[0007] As a preferred technical solution, the raw material for preparing the herbicidal composition further comprises at least one of dispersing agent, wetting agent, disintegrant, emulsifier, antifreeze agent, defoaming agent, thickener, filler, organic solvent, and water. As a preferred technical solution, the formulation of the herbicidal composition is a microemulsion, and the raw materials for preparing the microemulsion are 0.5% to 2.0% by mass of 3-(2-chloro-4-fluoro-5-(3-methyl-2,6-dioxo-4-trifluoromethyl-3,6-dihydropyrimidin-1(2H)-yl)phenyl)-5-methyl-4,5-dihydroisoxazole-5-carboxylic acid ethyl ester, 4.5% to 40% by mass of glufosinate-P, 2% to 8% by mass of organic solvent, 10% to 30% by mass of emulsifier, 0.01% to 0.1% by mass of antifoaming agent, 0.1% to 2% by mass of thickener, 1% to 10% by mass of antifreeze agent, and deionized water to be supplemented to 100% by mass. Including nothing.

[0008] As a preferred technical solution, the formulation of the herbicidal composition is an emulsion, and the raw materials for preparing the emulsion are 0.5% by mass to 2.0% by mass of 3-(2-chloro-4-fluoro-5-(3-methyl-2,6-dioxo-4-trifluoromethyl-3,6-dihydropyrimidin-1(2H)-yl)phenyl)-5-methyl-4,5-dihydroisoxazole-5-carboxylic acid ethyl ester, 4.5% by mass to 40% by mass of glufosinate-P, 2% by mass to 8% by mass of organic solvent, 2% by mass to 10% by mass of emulsifier, 0.01% by mass to 0.1% by mass of antifoaming agent, 0.1% by mass to 2% by mass of thickener, 1% by mass to 10% by mass of antifreeze agent, and deionized water to be supplemented to 100% by mass. Including nothing.

[0009] As a preferred technical solution, the formulation of the herbicidal composition is an oil suspension, and the raw materials for producing the oil suspension are 0.5% by mass to 2.0% by mass of 3-(2-chloro-4-fluoro-5-(3-methyl-2,6-dioxo-4-trifluoromethyl-3,6-dihydropyrimidin-1(2H)-yl)phenyl)-5-methyl-4,5-dihydroisoxazole-5-carboxylic acid ethyl ester, 9% by mass to 40% by mass of glufosinate-P, 4% by mass to 10% by mass of wetting agent, 3% by mass to 8% by mass of dispersing agent, 2% by mass to 5% by mass of emulsifying agent, 0% by mass to 10% by mass of thickening agent, 0% by mass to 5% by mass of defoaming agent, and organic solvent supplemented to 100% by mass. Includingnothing.

[0010] As a preferred technical solution, the formulation of the herbicidal composition is a wettable powder, and the raw materials for producing the wettable powder include 0.5% by mass to 5.0% by mass of 3-(2-chloro-4-fluoro-5-(3-methyl-2,6-dioxo-4-trifluoromethyl-3,6-dihydropyrimidin-1(2H)-yl)phenyl)-5-methyl-4,5-dihydroisoxazole-5-carboxylic acid ethyl ester, 4.5% by mass to 80% by mass of glufosinate-P, 0.5% by mass to 5% by mass of organic solvent, 1% by mass to 3% by mass of wetting agent, 2% by mass to 8% by mass of dispersant, 0.01% by mass to 0.1% by mass of defoamer, and filler to be supplemented to 100% by mass. Including nothing.

[0011] As a preferred technical solution, the formulation of the herbicidal composition is a water dispersible granule, and the raw materials for producing the water dispersible granule include 2% by mass to 9% by mass of 3-(2-chloro-4-fluoro-5-(3-methyl-2,6-dioxo-4-trifluoromethyl-3,6-dihydropyrimidin-1(2H)-yl)phenyl)-5-methyl-4,5-dihydroisoxazole-5-carboxylic acid ethyl ester, 35% by mass to 85% by mass of glufosinate-P, 2% by mass to 9% by mass of an organic solvent, 1% by mass to 5% by mass of a wetting agent, 5% by mass to 20% by mass of a dispersant, 0% by mass to 15% by mass of a disintegrant, and a filler that is added up to 100% by mass. Including nothing. As a preferred technical solution, the formulation of the herbicidal composition is a granule, and the raw materials for producing the granule include 0.5% by mass to 1.0% by mass of 3-(2-chloro-4-fluoro-5-(3-methyl-2,6-dioxo-4-trifluoromethyl-3,6-dihydropyrimidin-1(2H)-yl)phenyl)-5-methyl-4,5-dihydroisoxazole-5-carboxylic acid ethyl ester, 4.5% by mass to 20% by mass of glufosinate-P, 0.5% by mass to 2% by mass of a wetting agent, 1% by mass to 4% by mass of a dispersing agent, 0.5% by mass to 2% by mass of an emulsifying agent, 5% by mass to 15% by mass of an organic solvent, and a filler to be supplemented to 100% by mass. Including nothing.

[0012] In a preferred technical solution, the mass ratio of said 3-(2-chloro-4-fluoro-5-(3-methyl-2,6-dioxo-4-trifluoromethyl-3,6-dihydropyrimidin-1(2H)-yl)phenyl)-5-methyl-4,5-dihydroisoxazole-5-carboxylic acid ethyl ester to glufosinate-P is 1:(9-20).

[0013] Based on the system of the present invention, 3-(2-chloro-4-fluoro-5-(3-methyl-2,6-dioxo-4-trifluoromethyl-3,6-dihydropyrimidin-1(2H)-yl)phenyl)-5-methyl-4,5-dihydroisoxazole-5-carboxylic acid ethyl ester and glufosinate-P are used as active ingredients, and in particular, the herbicidal effect of 3-(2-chloro-4-fluoro-5-(3-methyl-2,6-dioxo-4-trifluoromethyl-3,6-dihydropyrimidin-1(2H)-yl)phenyl)-5-methyl-4,5-dihydroisoxazole-5-carboxylic acid ethyl ester and glufosinate-P when mixed in various ratios was evaluated, particularly 3- When the mass ratio of (2-chloro-4-fluoro-5-(3-methyl-2,6-dioxo-4-trifluoromethyl-3,6-dihydropyrimidin-1(2H)-yl)phenyl)-5-methyl-4,5-dihydroisoxazole-5-carboxylic acid ethyl ester to glufosinate-P is 1:(9-20), a synergistic herbicidal effect was observed against grass weeds such as goosegrass, crabgrass, Chinese dwarf grass, thatch, and reed, broadleaf weeds and small shrub weeds such as artemisia, solidago altissima, long-legged weed, and nightshade, as well as sedge, and it was found that the two types of herbicides act synergistically through different herbicidal mechanisms, allowing the amount of herbicides to be reduced.

[0014] As a preferred technical solution, the dispersant is at least one selected from dispersant NNO, dispersant MF, dispersant NO, sodium lignosulfonate, sodium carboxymethylcellulose, polyvinyl alcohol, polyethylene glycol, sodium tripolyphosphate, and sodium tripolyphosphate.

[0015] As a preferred technical solution, the wetting agent is at least one selected from tea seed cake, saponin, SOPA230, SOPA 235, SOPA 270, powder detergent, and sodium dodecylbenzenesulfonate.

[0016] As a preferred technical solution, the disintegrant is at least one selected from sodium chloride, sodium sulfate, sodium nitrate, ammonium sulfate, sodium carbonate, sodium carboxymethyl starch, sodium alginate, polyvinylpyrrolidone, and bentonite.

[0017] As a preferred technical solution, the emulsifier is at least one selected from alkylphenol polyoxyethylene ether, phenylethylphenol polyoxyethylene polyoxypropylene ether, polyoxyethylene sorbitan monolaurate, polyoxyethylene sorbitan monopalmitate, polyoxyethylene sorbitan monostearate, sorbitan monooleate, sorbitan laurate, sorbitan monopalmitate, sorbitan stearate, castor oil polyoxyethylene ether, alkylbenzenesulfonate, alkylnaphthalenesulfonate, and alkylsulfonate.

[0018] As a preferred technical solution, the antifreeze agent is at least one selected from ethylene glycol, propylene glycol, glycerin, hexylene glycol, urea, and ammonium sulfate.

[0019] As a preferred technical solution, the defoaming agent is at least one of an alcohol-based defoaming agent, a phosphate-based defoaming agent, a fatty acid and fatty acid ester-based defoaming agent, and a silicone-based defoaming agent. The alcohol-based defoaming agent is at least one of methanol, ethanol, and butanol, the phosphate-based defoaming agent is at least one of tributyl phosphate, trioctyl phosphate, and alkyl ether phosphate, and the fatty acid and fatty acid ester-based defoaming agent is at least one of sorbitan monolaurate and fatty alcohol polyoxyethylene ether.

[0020] As a preferred technical solution, the thickening agent is one or more selected from gelatin, guar gum, magnesium aluminum silicate, hydroxyethyl cellulose, sodium tripolyphosphate, phenolic resin, methyl cellulose, polyethylene glycol, and polyvinyl alcohol.

[0021] As a preferred technical solution, the filler is one or more selected from kaolin, diatomaceous earth, bentonite, attapulgite, white carbon black, starch, and precipitated calcium carbonate.

[0022] As a preferred technical solution, the organic solvent is at least one of aromatic hydrocarbons, paraffins, aliphatic hydrocarbons, petroleum products, ketones, ethers, alcohols, turpentine, pine oil, rosin oil vegetable oil solvent, vegetable oil, and modified vegetable oil.

[0023] Another aspect of the present invention provides the use of a herbicidal composition containing 3-(2-chloro-4-fluoro-5-(3-methyl-2,6-dioxo-4-trifluoromethyl-3,6-dihydropyrimidin-1(2H)-yl)phenyl)-5-methyl-4,5-dihydroisoxazole-5-carboxylic acid ethyl ester and glufosinate-P for controlling weeds in non-arable land. Effect of the Invention

[0024] The beneficial effects are as follows:

[0025] 1. The present invention provides a herbicidal composition containing 3-(2-chloro-4-fluoro-5-(3-methyl-2,6-dioxo-4-trifluoromethyl-3,6-dihydropyrimidin-1(2H)-yl)phenyl)-5-methyl-4,5-dihydroisoxazole-5-carboxylic acid ethyl ester and glufosinate-P, and use thereof. By combining 3-(2-chloro-4-fluoro-5-(3-methyl-2,6-dioxo-4-trifluoromethyl-3,6-dihydropyrimidin-1(2H)-yl)phenyl)-5-methyl-4,5-dihydroisoxazole-5-carboxylic acid ethyl ester with glufosinate-P, the herbicidal spectrum is expanded, the herbicidal effect is improved, it has fast-acting effect, long duration of action, can delay herbicide resistance, thorough weed control, low residual, low toxicity, high safety and environmental friendliness, and has excellent control effect on weeds in non-cultivated land.

[0026] 2. Based on the system of the present invention, 3-(2-chloro-4-fluoro-5-(3-methyl-2,6-dioxo-4-trifluoromethyl-3,6-dihydropyrimidin-1(2H)-yl)phenyl)-5-methyl-4,5-dihydroisoxazole-5-carboxylic acid ethyl ester and glufosinate-P are used as active ingredients, and in particular, the herbicidal effect of 3-(2-chloro-4-fluoro-5-(3-methyl-2,6-dioxo-4-trifluoromethyl-3,6-dihydropyrimidin-1(2H)-yl)phenyl)-5-methyl-4,5-dihydroisoxazole-5-carboxylic acid ethyl ester and glufosinate-P when mixed in various ratios is evaluated, particularly 3 When the mass ratio of -(2-chloro-4-fluoro-5-(3-methyl-2,6-dioxo-4-trifluoromethyl-3,6-dihydropyrimidin-1(2H)-yl)phenyl)-5-methyl-4,5-dihydroisoxazole-5-carboxylic acid ethyl ester to glufosinate-P is 1:(9-20), a synergistic herbicidal effect was observed against grass weeds such as goosegrass, crabgrass, Chinese dwarf grass, thatch, and reed, broadleaf weeds and small shrub weeds such as artemisia, solidago altissima, long-legged weed, and nightshade, as well as sedge, and it was found that the two types of herbicides act synergistically through different herbicidal mechanisms, allowing the amount of herbicides to be reduced.

[0027] 3. The herbicidal composition according to the present invention containing 3-(2-chloro-4-fluoro-5-(3-methyl-2,6-dioxo-4-trifluoromethyl-3,6-dihydropyrimidin-1(2H)-yl)phenyl)-5-methyl-4,5-dihydroisoxazole-5-carboxylic acid ethyl ester and glufosinate-P can be formulated into a microemulsion, an emulsion, an oil suspension, a wettable powder, a water dispersible granule or a granule in order to meet the needs of various usage environments and usage scenes. DETAILED DESCRIPTION OF THE PREFERRED EMBODIMENTS

[0028] Example 1 Example 1 of the present invention provides a herbicidal composition containing 3-(2-chloro-4-fluoro-5-(3-methyl-2,6-dioxo-4-trifluoromethyl-3,6-dihydropyrimidin-1(2H)-yl)phenyl)-5-methyl-4,5-dihydroisoxazole-5-carboxylic acid ethyl ester and glufosinate-P, the formulation of the herbicidal composition is a microemulsion, and the raw material for preparing the microemulsion is 3-(2- Contains 1.0% by weight of chloro-4-fluoro-5-(3-methyl-2,6-dioxo-4-trifluoromethyl-3,6-dihydropyrimidin-1(2H)-yl)phenyl)-5-methyl-4,5-dihydroisoxazole-5-carboxylic acid ethyl ester, 20% by weight of glufosinate-P, 5% by weight of organic solvent, 20% by weight of emulsifier, 0.05% by weight of antifoam, 1% by weight of thickener, 5% by weight of antifreeze, and deionized water to make up to 100% by weight. The organic solvent is mineral spirits 150#. The emulsifier is phenylethylphenol polyoxyethylene polyoxypropylene ether produced by Nantong Chenrun Chemical Co., Ltd. The antifreeze agent is ethylene glycol and urea, and the mass ratio of the ethylene glycol to the urea is 3:2. The antifoaming agent is a fatty acid and fatty acid ester-based antifoaming agent, and the fatty acid and fatty acid ester-based antifoaming agent is sorbitan monolaurate. The thickening agent is sodium tripolyphosphate.

[0029] Example 2 Example 2 of the present invention provides a herbicidal composition containing 3-(2-chloro-4-fluoro-5-(3-methyl-2,6-dioxo-4-trifluoromethyl-3,6-dihydropyrimidin-1(2H)-yl)phenyl)-5-methyl-4,5-dihydroisoxazole-5-carboxylic acid ethyl ester and glufosinate-P, the formulation of the herbicidal composition is a microemulsion, and the specific embodiment is the same as that of Example 1, except that the method for preparing the microemulsion is the same as that of Example 1. The difference is that the raw materials used include 1.0% by weight of 3-(2-chloro-4-fluoro-5-(3-methyl-2,6-dioxo-4-trifluoromethyl-3,6-dihydropyrimidin-1(2H)-yl)phenyl)-5-methyl-4,5-dihydroisoxazole-5-carboxylic acid ethyl ester, 18% by weight of glufosinate-P, 5% by weight of organic solvent, 20% by weight of emulsifier, 0.05% by weight of antifoam, 1% by weight of thickener, 5% by weight of antifreeze, and deionized water to make up to 100% by weight.

[0030] Example 3 Example 3 of the present invention provides a herbicidal composition containing 3-(2-chloro-4-fluoro-5-(3-methyl-2,6-dioxo-4-trifluoromethyl-3,6-dihydropyrimidin-1(2H)-yl)phenyl)-5-methyl-4,5-dihydroisoxazole-5-carboxylic acid ethyl ester and glufosinate-P, the formulation of the herbicidal composition is a microemulsion, and the specific embodiment is the same as that of Example 1, except that the raw materials for preparing the microemulsion are 1.0 mass% of 3-(2-chloro-4-fluoro-5-(3-methyl-2,6-dioxo-4-trifluoromethyl-3,6-dihydropyrimidin-1(2H)-yl)phenyl)-5-methyl-4,5-dihydroisoxazole-5-carboxylic acid ethyl ester, 1.0 mass% of glufosinate-P, and 1.0 mass% of glufosinate-P. 16% by weight, organic solvent 5% by weight, emulsifier 20% by weight, antifoaming agent 0.05% by weight, thickener 1% by weight, antifreeze 5% by weight, and deionized water to make up to 100% by weight.

[0031] Example 4 Example 4 of the present invention provides a herbicidal composition containing 3-(2-chloro-4-fluoro-5-(3-methyl-2,6-dioxo-4-trifluoromethyl-3,6-dihydropyrimidin-1(2H)-yl)phenyl)-5-methyl-4,5-dihydroisoxazole-5-carboxylic acid ethyl ester and glufosinate-P, the formulation of the herbicidal composition is a microemulsion, and the specific embodiment is the same as that of Example 1, except that the method for preparing the microemulsion is the same as that of Example 1. The difference is that the raw materials used include 1.0% by weight of 3-(2-chloro-4-fluoro-5-(3-methyl-2,6-dioxo-4-trifluoromethyl-3,6-dihydropyrimidin-1(2H)-yl)phenyl)-5-methyl-4,5-dihydroisoxazole-5-carboxylic acid ethyl ester, 14% by weight of glufosinate-P, 5% by weight of organic solvent, 20% by weight of emulsifier, 0.05% by weight of antifoam, 1% by weight of thickener, 5% by weight of antifreeze, and deionized water to make up to 100% by weight.

[0032] Example 5 Example 5 of the present invention provides a herbicidal composition comprising 3-(2-chloro-4-fluoro-5-(3-methyl-2,6-dioxo-4-trifluoromethyl-3,6-dihydropyrimidin-1(2H)-yl)phenyl)-5-methyl-4,5-dihydroisoxazole-5-carboxylic acid ethyl ester and glufosinate-P, the formulation of the herbicidal composition is a microemulsion, and the specific embodiment is the same as that of Example 1, except that the method for preparing the microemulsion is the same as that of Example 1. The difference is that the raw materials used include 1.0% by weight of 3-(2-chloro-4-fluoro-5-(3-methyl-2,6-dioxo-4-trifluoromethyl-3,6-dihydropyrimidin-1(2H)-yl)phenyl)-5-methyl-4,5-dihydroisoxazole-5-carboxylic acid ethyl ester, 10% by weight of glufosinate-P, 5% by weight of organic solvent, 20% by weight of emulsifier, 0.05% by weight of antifoam, 1% by weight of thickener, 5% by weight of antifreeze, and deionized water to make up to 100% by weight.

[0033] Example 6 Example 6 of the present invention provides a herbicidal composition comprising 3-(2-chloro-4-fluoro-5-(3-methyl-2,6-dioxo-4-trifluoromethyl-3,6-dihydropyrimidin-1(2H)-yl)phenyl)-5-methyl-4,5-dihydroisoxazole-5-carboxylic acid ethyl ester and glufosinate-P, the formulation of the herbicidal composition is an emulsion, and the raw material for preparing the emulsion is 3-(2-chloro-4-fluoro 1.0% by weight of 5-(3-methyl-2,6-dioxo-4-trifluoromethyl-3,6-dihydropyrimidin-1(2H)-yl)phenyl)-5-methyl-4,5-dihydroisoxazole-5-carboxylic acid ethyl ester, 20% by weight of glufosinate-P, 4% by weight of organic solvent, 8% by weight of emulsifier, 0.03% by weight of antifoam, 1% by weight of thickener, 6% by weight of antifreeze, and deionized water to make up to 100% by weight. The organic solvent is isopropyl alcohol. The emulsifier is phenylethylphenol polyoxyethylene polyoxypropylene ether produced by Nantong Chenrun Chemical Co., Ltd. The antifreeze agent is ethylene glycol and urea, and the mass ratio of the ethylene glycol to the urea is 3:2. The antifoaming agent is a fatty acid and fatty acid ester-based antifoaming agent, and the fatty acid and fatty acid ester-based antifoaming agent is sorbitan monolaurate. The thickening agent is magnesium aluminum silicate.

[0034] Example 7 Example 7 of the present invention provides a herbicidal composition comprising 3-(2-chloro-4-fluoro-5-(3-methyl-2,6-dioxo-4-trifluoromethyl-3,6-dihydropyrimidin-1(2H)-yl)phenyl)-5-methyl-4,5-dihydroisoxazole-5-carboxylic acid ethyl ester and glufosinate-P, the formulation of the herbicidal composition is an oil suspension, and the raw material for preparing the oil suspension is 3-(2- Contains 1% by weight of chloro-4-fluoro-5-(3-methyl-2,6-dioxo-4-trifluoromethyl-3,6-dihydropyrimidin-1(2H)-yl)phenyl)-5-methyl-4,5-dihydroisoxazole-5-carboxylic acid ethyl ester, 20% by weight of glufosinate-P, 6% by weight of wetting agent, 5% by weight of dispersing agent, 3% by weight of emulsifying agent, 2% by weight of thickening agent, 1% by weight of defoamer, and organic solvents to make up to 100% by weight. The dispersant is dispersant NNO. The wetting agent is SOPA230. The organic solvent is mineral spirits 200#. The emulsifier is phenylethylphenol polyoxyethylene polyoxypropylene ether produced by Nantong Chenrun Chemical Co., Ltd. The antifoaming agent is a fatty acid and fatty acid ester-based antifoaming agent, and the fatty acid and fatty acid ester-based antifoaming agent is sorbitan monolaurate. The thickening agent is gelatin.

[0035] Example 8 Example 8 of the present invention provides a herbicidal composition containing 3-(2-chloro-4-fluoro-5-(3-methyl-2,6-dioxo-4-trifluoromethyl-3,6-dihydropyrimidin-1(2H)-yl)phenyl)-5-methyl-4,5-dihydroisoxazole-5-carboxylic acid ethyl ester and glufosinate-P, the formulation of the herbicidal composition is a wettable powder, and the raw materials for preparing the wettable powder include 3% by weight of 3-(2-chloro-4-fluoro-5-(3-methyl-2,6-dioxo-4-trifluoromethyl-3,6-dihydropyrimidin-1(2H)-yl)phenyl)-5-methyl-4,5-dihydroisoxazole-5-carboxylic acid ethyl ester, 60% by weight of glufosinate-P, 3% by weight of organic solvent, 2% by weight of wetting agent, 5% by weight of dispersant, 0.06% by weight of defoamer, and a filler to be supplemented to 100% by weight. The dispersant is sodium lignosulfonate. The wetting agent is sodium dodecylbenzenesulfonate. The organic solvent is mineral spirits 200#. The antifoaming agent is a fatty acid and fatty acid ester-based antifoaming agent, and the fatty acid and fatty acid ester-based antifoaming agent is sorbitan monolaurate. The filler is kaolin.

[0036] Example 9 Example 9 of the present invention provides a herbicidal composition containing 3-(2-chloro-4-fluoro-5-(3-methyl-2,6-dioxo-4-trifluoromethyl-3,6-dihydropyrimidin-1(2H)-yl)phenyl)-5-methyl-4,5-dihydroisoxazole-5-carboxylic acid ethyl ester and glufosinate-P, the herbicidal composition is in the form of a water dispersible granule, and the raw materials for preparing the water dispersible granule include 4% by weight of 3-(2-chloro-4-fluoro-5-(3-methyl-2,6-dioxo-4-trifluoromethyl-3,6-dihydropyrimidin-1(2H)-yl)phenyl)-5-methyl-4,5-dihydroisoxazole-5-carboxylic acid ethyl ester, 64% by weight of glufosinate-P, 5% by weight of an organic solvent, 3% by weight of a wetting agent, 10% by weight of a dispersant, 5% by weight of a disintegrant, and a filler that is filled up to 100% by weight. The dispersant is sodium lignosulfonate. The wetting agent is sodium dodecylbenzenesulfonate. The organic solvent is isopropyl alcohol. The disintegrant is sodium alginate. The filler is kaolin.

[0037] Example 10 Example 10 of the present invention provides a herbicidal composition containing 3-(2-chloro-4-fluoro-5-(3-methyl-2,6-dioxo-4-trifluoromethyl-3,6-dihydropyrimidin-1(2H)-yl)phenyl)-5-methyl-4,5-dihydroisoxazole-5-carboxylic acid ethyl ester and glufosinate-P, the formulation of the herbicidal composition is granules, and the raw materials for preparing the granules include 0.8% by weight of 3-(2-chloro-4-fluoro-5-(3-methyl-2,6-dioxo-4-trifluoromethyl-3,6-dihydropyrimidin-1(2H)-yl)phenyl)-5-methyl-4,5-dihydroisoxazole-5-carboxylic acid ethyl ester, 16% by weight of glufosinate-P, 1% by weight of a wetting agent, 3% by weight of a dispersing agent, 1% by weight of an emulsifying agent, 10% by weight of an organic solvent, and a filler that is supplemented to 100% by weight. The dispersant is Dispersant MF. The wetting agent is SOPA 270. The emulsifier is phenylethylphenol polyoxyethylene polyoxypropylene ether produced by Nantong Chenrun Chemical Co., Ltd. The filler is kaolin. The organic solvent is mineral spirits 150#.

[0038] Performance Test Method 1. Indoor activity measurement test (1) Study objective: To determine the inhibitory effects of 3-(2-chloro-4-fluoro-5-(3-methyl-2,6-dioxo-4-trifluoromethyl-3,6-dihydropyrimidin-1(2H)-yl)phenyl)-5-methyl-4,5-dihydroisoxazole-5-carboxylic acid ethyl ester, glufosinate-P, and various combinations thereof against Artemisia gracilis under greenhouse potted conditions, and to evaluate their combined actions. The relevant results are shown in Table 1. 1 As shown in. (2) Test method: The research subject was Artemisia gracilis. Organic soil (pH 6.7, organic matter content 1.59%) without herbicide treatment was placed in a 22 x 15 x 10 cm plastic bowl. 20 seeds were evenly spread in each pot, and when the weeds grew to the 2-4 leaf stage, the stems and leaves were treated using a spray tower. Each treatment was repeated 4 times, and a blank control was set up. After the chemical solution dried, the test materials were placed in a greenhouse and cultivated. The damage to the weeds was observed 15 and 30 days after the chemical application, the fresh weight of the aboveground part was measured, and the toxic effect of the chemical on the weeds was evaluated from the inhibition rate of the target weeds. The method for evaluating the combined action of two components was based on the Gowing method in the measurement of the combined action of mixtures in the guidelines for indoor bioassay of pesticides. Fresh weight inhibition rate % = (control fresh weight - treatment fresh weight) / control fresh weight x 100 E 0 =X+Y-XY / 100 In the above formula, E 0is the theoretical fresh weight inhibition rate after combining 3-(2-chloro-4-fluoro-5-(3-methyl-2,6-dioxo-4-trifluoromethyl-3,6-dihydropyrimidin-1(2H)-yl)phenyl)-5-methyl-4,5-dihydroisoxazole-5-carboxylic acid ethyl ester and glufosinate-P as herbicides, X is the measured fresh weight inhibition rate of the herbicide 3-(2-chloro-4-fluoro-5-(3-methyl-2,6-dioxo-4-trifluoromethyl-3,6-dihydropyrimidin-1(2H)-yl)phenyl)-5-methyl-4,5-dihydroisoxazole-5-carboxylic acid ethyl ester alone, and Y is the measured fresh weight inhibition rate of the herbicide glufosinate-P alone. The actual live weight inhibition rate after mixing 3-(2-chloro-4-fluoro-5-(3-methyl-2,6-dioxo-4-trifluoromethyl-3,6-dihydropyrimidin-1(2H)-yl)phenyl)-5-methyl-4,5-dihydroisoxazole-5-carboxylic acid ethyl ester with glufosinate-P is E, and the EE 0 If ≧10, synergy, -10 <E-E 0 If <10, additive effect, EE 0 A value of ≦−10 indicates antagonism.

[0039] 2. Field Efficacy Testing Test Agents: The formulations provided in Examples 1-5 were subjected to field testing. Control agent: 66% flumioxazin-glufosinate ammonium hydrate (commercially available) 40% saflufenacil-glyphosate oil suspension (commercially available) Target of control: Weeds in non-cultivated land. The weeds in the selected test farmland mainly include grass family weeds such as crabgrass, Japanese larkspur, and thatch, and broad-leaved weeds such as artemisia, nightshade, and polygonum. Test method: Each type of herbicide was accurately weighed according to the area of ​​the test plot, diluted with water, and sprayed evenly using a knapsack sprayer. A fan-shaped nozzle specially designed for herbicides was used. When spraying, care was taken to ensure that the herbicide solution was evenly distributed within the test plot, without overlapping or missing areas. Survey: Weed death was observed 15 and 30 days after application of the agent, and the herbicidal activity of each treatment was compared. 2 and table 3 As shown in.

[0040] [Table 1]

[0041] [Table 2]

[0042] [Table 3]

[0043] As described above, from Tables 1 to 3, it can be seen that in the present invention, the combined use of two pesticide active ingredients improves the overall control effect, significantly improves the immediate effect, and in hot weather, a significant effect is observed 2 hours after application, the duration of action is significantly extended, the herbicidal spectrum is further expanded, and a significant synergistic effect is exerted in the control of grass weeds and broadleaf weeds. In addition, the mixed herbicide of the present invention is superior to the use of a single agent, and is equivalent to or superior to commercially available compound herbicides. Furthermore, the mixed herbicide of the present invention is advantageous in delaying the development of weed resistance.

Claims

1. 1. A herbicidal composition comprising 3-(2-chloro-4-fluoro-5-(3-methyl-2,6-dioxo-4-trifluoromethyl-3,6-dihydropyrimidin-1(2H)-yl)phenyl)-5-methyl-4,5-dihydroisoxazole-5-carboxylic acid ethyl ester and glufosinate-P, The raw material for production contains at least 3-(2-chloro-4-fluoro-5-(3-methyl-2,6-dioxo-4-trifluoromethyl-3,6-dihydropyrimidin-1(2H)-yl)phenyl)-5-methyl-4,5-dihydroisoxazole-5-carboxylic acid ethyl ester and glufosinate-P; 1. The herbicidal composition, wherein the formulation of the herbicidal composition is at least one of a microemulsion, an emulsion, an oil suspension, a granule, a wettable powder, and a water dispersible granule.

2. The herbicidal composition comprising 3-(2-chloro-4-fluoro-5-(3-methyl-2,6-dioxo-4-trifluoromethyl-3,6-dihydropyrimidin-1(2H)-yl)phenyl)-5-methyl-4,5-dihydroisoxazole-5-carboxylic acid ethyl ester and glufosinate-P according to claim 1, characterized in that the raw material for producing the herbicidal composition further comprises at least one of a dispersant, a wetting agent, a disintegrant, an emulsifier, an antifreeze agent, an antifoaming agent, a thickener, a filler, an organic solvent, and water.

3. The formulation of the herbicidal composition is a microemulsion, and the raw materials for producing the microemulsion are 0.5% by mass to 2.0% by mass of 3-(2-chloro-4-fluoro-5-(3-methyl-2,6-dioxo-4-trifluoromethyl-3,6-dihydropyrimidin-1(2H)-yl)phenyl)-5-methyl-4,5-dihydroisoxazole-5-carboxylic acid ethyl ester, glufosinate-P 4.5% to 40% by weight of an organic solvent, 2% to 8% by weight of an emulsifier, 10% to 30% by weight of an emulsifier, 0.01% to 0.1% by weight of an antifoaming agent, 0.1% to 2% by weight of a thickener, 1% to 10% by weight of an antifreeze agent, and deionized water to make up to 100% by weight.

4. The formulation of the herbicidal composition is an emulsion, and the raw materials for producing the emulsion are 0.5% by mass to 2.0% by mass of 3-(2-chloro-4-fluoro-5-(3-methyl-2,6-dioxo-4-trifluoromethyl-3,6-dihydropyrimidin-1(2H)-yl)phenyl)-5-methyl-4,5-dihydroisoxazole-5-carboxylic acid ethyl ester, glufosinate-P 4.5% to 40% by weight of an organic solvent, 2% to 8% by weight of an emulsifier, 2% to 10% by weight of an antifoaming agent, 0.01% to 0.1% by weight of a thickener, 0.1% to 2% by weight of a freeze protectant, and deionized water to make up to 100% by weight.

5. The formulation of the herbicidal composition is an oil suspension, and raw materials for producing the oil suspension include 0.5% by mass to 2.0% by mass of 3-(2-chloro-4-fluoro-5-(3-methyl-2,6-dioxo-4-trifluoromethyl-3,6-dihydropyrimidin-1(2H)-yl)phenyl)-5-methyl-4,5-dihydroisoxazole-5-carboxylic acid ethyl ester, 9% by mass to 40% by mass of glufosinate-P, 4% by mass to 10% by mass of a wetting agent, 3% by mass to 8% by mass of a dispersing agent, and an emulsifier.

3. The herbicidal composition containing 3-(2-chloro-4-fluoro-5-(3-methyl-2,6-dioxo-4-trifluoromethyl-3,6-dihydropyrimidin-1(2H)-yl)phenyl)-5-methyl-4,5-dihydroisoxazole-5-carboxylic acid ethyl ester and glufosinate-P according to claim 2, characterized in that it contains at least 2% by weight to 5% by weight of an organic solvent, 0% by weight to 10% by weight of a thickener, 0% by weight to 5% by weight of an antifoaming agent, and an organic solvent making up to 100% by weight.

6. The formulation of the herbicidal composition is a wettable powder, and the raw materials for producing the wettable powder include 0.5% by mass to 5.0% by mass of 3-(2-chloro-4-fluoro-5-(3-methyl-2,6-dioxo-4-trifluoromethyl-3,6-dihydropyrimidin-1(2H)-yl)phenyl)-5-methyl-4,5-dihydroisoxazole-5-carboxylic acid ethyl ester, glufosinate-P 4.5% to 80% by weight of an organic solvent, 0.5% to 5% by weight of a wetting agent, 1% to 3% by weight of a dispersant, 2% to 8% by weight of a defoamer, 0.01% to 0.1% by weight of a filler to make up to 100% by weight.

7. The formulation of the herbicidal composition is a water dispersible granule, and raw materials for producing the water dispersible granule include 2% by mass to 9% by mass of 3-(2-chloro-4-fluoro-5-(3-methyl-2,6-dioxo-4-trifluoromethyl-3,6-dihydropyrimidin-1(2H)-yl)phenyl)-5-methyl-4,5-dihydroisoxazole-5-carboxylic acid ethyl ester, 35% by mass to 85% by mass of glufosinate-P, 2% by mass to 9% by mass of an organic solvent, and 1% by mass to 5% by mass of a wetting agent. % by weight, 5% to 20% by weight of a dispersant, 0% to 15% by weight of a disintegrant, and a filler making up to 100% by weight.

8. The formulation of the herbicidal composition is a granule, and the raw materials for producing the granule include 0.5% by mass to 1.0% by mass of 3-(2-chloro-4-fluoro-5-(3-methyl-2,6-dioxo-4-trifluoromethyl-3,6-dihydropyrimidin-1(2H)-yl)phenyl)-5-methyl-4,5-dihydroisoxazole-5-carboxylic acid ethyl ester, glufosinate-P 4.5% to 20% by weight of a herbicidal composition containing 3-(2-chloro-4-fluoro-5-(3-methyl-2,6-dioxo-4-trifluoromethyl-3,6-dihydropyrimidin-1(2H)-yl)phenyl)-5-methyl-4,5-dihydroisoxazole-5-carboxylic acid ethyl ester and glufosinate-P, characterized in that the herbicidal composition contains at least 4.5% to 20% by weight of a wetting agent, 0.5% to 2% by weight of a dispersing agent, 1% to 4% by weight of a dispersing agent, 0.5% to 2% by weight of an emulsifying agent, 5% to 15% by weight of an organic solvent, and a filler making up to 100% by weight.

9. The herbicidal composition containing 3-(2-chloro-4-fluoro-5-(3-methyl-2,6-dioxo-4-trifluoromethyl-3,6-dihydropyrimidin-1(2H)-yl)phenyl)-5-methyl-4,5-dihydroisoxazole-5-carboxylic acid ethyl ester and glufosinate-P according to any one of claims 1 to 8, characterized in that a mass ratio of the 3-(2-chloro-4-fluoro-5-(3-methyl-2,6-dioxo-4-trifluoromethyl-3,6-dihydropyrimidin-1(2H)-yl)phenyl)-5-methyl-4,5-dihydroisoxazole-5-carboxylic acid ethyl ester to glufosinate-P is 1:(9 to 20).

10. Use of a herbicidal composition comprising 3-(2-chloro-4-fluoro-5-(3-methyl-2,6-dioxo-4-trifluoromethyl-3,6-dihydropyrimidin-1(2H)-yl)phenyl)-5-methyl-4,5-dihydroisoxazole-5-carboxylic acid ethyl ester and glufosinate-P according to claim 9, 1. The use of the composition for controlling weeds in non-cultivated land.

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