Cleansing composition for removing blackheads

Abstract

This invention provides the use of an aqueous composition suitable for cleansing the skin to efficiently remove blackheads. [Solution] A cosmetic composition for removing blackheads comprising: (A): a polyglycerin fatty acid ester made from C8 fatty acid and polyglycerin having a degree of polymerization of 5 to 7 in glycerin; (B): a polyglycerin fatty acid ester made from C10 fatty acid and polyglycerin having a degree of polymerization of 5 to 7 in glycerin; (C): a liquid oil; (D): sodium surfactin; and (E): an aqueous phase, wherein the total amount of (A) and (B) is 1 to 15% by mass of the total mass of the cosmetic composition, the mass ratio of (C) to the total amount of (A) and (B) ((C) / (A)+(B)) is 0.05 to 0.4, (A) and (B) have a mixed HLB of 12.4 to 14.2, and the total amount of (D) is 0.2 to 2.5% by mass of the total mass of the cosmetic composition.

Description

Technical Field

[0003] , , ,

[0001] The present invention relates to the use of an aqueous composition suitable for cleansing the skin, and relates to an aqueous composition that is efficient for the removal of keratin plugs.

Background Art

[0002] Keratin plugs (commonly known as comedones) are known to cause various skin problems, such as acne, dark spots, and generally undesirable skin irregularities, by clogging pores. Despite the prevalence of keratin plugs, their removal remains a significant challenge. Keratin plugs are highly resistant to removal due to their compressed and hardened structure. Conventional methods for their extraction typically involve either physical removal such as manual extraction or exfoliation, or the use of harsh chemicals such as salicylic acid or retinoids. However, these methods have several drawbacks. As far as physical methods are concerned, techniques such as manual extraction or exfoliation are painful, time-consuming, and often require professional intervention, yet still, if not performed correctly, can result in skin irritation, damage, or scarring. Common detergents such as soap do not dissolve keratin plugs at all. Although effective in dissolving keratin plugs, strong chemicals can cause skin irritation, redness, exfoliation, and increased sensitivity, particularly in individuals with particularly sensitive or reactive skin types. Long-term use of such chemicals can also impair the skin barrier function and lead to further dermatological problems. There is a clear and unmet need for an aqueous cleansing cosmetic composition that can effectively and gently remove keratin plugs without the adverse effects associated with physical extraction or the use of harsh chemicals. The cleansing action is a complex physical and chemical interaction between water, detergents, and keratinous substances. Cleansers are effective in maintaining skin hygiene and a healthy skin barrier, but can cause damage by the surfactants contained therein.

[0003] Furthermore, a good cleansing product must thoroughly cleanse the skin from dust, lotion, and makeup, as well as dirt, sebum, sweat, and exfoliated dead skin cells. To achieve this cleansing effect, the product must remove fat-soluble substances (sebum, cream, and makeup) and water-soluble substances (sweat residue).

[0004] In addition, there is a particularly strong consumer demand for cosmetics with a higher degree of natural origin, and there is a need to shift towards more environmentally friendly alternative water-based cosmetics.

[0005] Since most makeup products are oil-soluble, the cleansing power of water-based cleansing cosmetics, such as cleansing water, lotion, and gel, is often inferior to that of oil-based or emulsion-based cleansing cosmetics. Therefore, technologies to improve the cleansing power of water-based cleansing cosmetics are desired. However, cleansing cosmetics containing high concentrations of surfactants are known to exhibit high cleansing effectiveness but also cause skin irritation. It is generally difficult to achieve sufficient cleansing effectiveness with lower surfactant concentrations, and concerns about skin stress due to friction remain.

[0006] Among surfactants, anionic surfactants and / or ethoxylated surfactants are known to be compatible with a wide range of formulations, thus providing flexibility in formulations and making them key ingredients in cleansing products. One of the most widely known examples of anionic surfactants is ammonium lauryl sulfate (ALS). However, some anionic surfactants are known to disrupt the lipids of the stratum corneum and are therefore unsuitable for application to the skin and are no longer used in consumer products. In fact, they are known to adversely affect skin keratinocytes and cause irritation, especially when left on the skin, as in the case of leave-on cleansing products.

[0007] Anionic surfactants can be modified to make them less irritating. For example, ammonium lauryl sulfate can be reacted with ethylene oxide to "ethoxylate" it and produce ammonium laureth sulfate. This additional chemical treatment makes the final product significantly less irritating and slightly more water-soluble. However, "ethoxylated" surfactants are still criticized due to their environmental impact. For these reasons, there is a particularly strong consumer demand for cosmetics containing alternative surfactants that are more considerate of the skin and the environment.

[0008] There is still a need for a water-based cleansing composition that is non-irritating to the skin and can remove comedones.

[0009] The present invention provides an unexpectedly advantageous solution to all these requirements by incorporating a novel, specific surfactant that completely replaces the ethoxylated anionic surfactant that was considered essential in the prior art. Therefore, the object of the present invention is to provide a novel composition that can promote the removal of keratin plugs and is non-irritating to the skin. [Overview of the Initiative]

[0010] The new cosmetic composition overcomes these challenges by combining a specific polyglycerin derivative with sodium surfactant biosurfactant. Sodium surfactant biosurfactant is a mild surfactant present at concentrations of less than 4%. Such a new cosmetic composition has a bicontinuous structure and can remove blackheads.

[0011] Surfactin was named by Arima of the University of Tokyo. Surfactin is a substance derived from the culture medium of Bacillus subtilis, and its structure was determined by Kakiuchi et al. Surfactin is a lipopeptide having a cyclic peptide as the hydrophilic part and an alkyl side chain as the hydrophobic part. The aspartic acid and glutamic acid in the cyclic peptide have free carboxyl groups, and their sodium salts function as anionic surfactants.

[0012] Sodium surfactin also meets the ongoing needs for sustainability and environmental considerations in cosmetics. Therefore, sodium surfactin is a highly biodegradable biosurfactant produced by microorganisms that does not contain petroleum-derived components in its structure.

[0013] The present invention relates to the following components (A) to (E): -Component (A): Polyglycerin fatty acid ester made from a fatty acid having 8 carbon atoms and polyglycerin having a glycerin polymerization degree of 5-7. -Component (B): Polyglycerin fatty acid ester made from a fatty acid having 10 carbon atoms and polyglycerin having a glycerin polymerization degree of 5-7. -Component (C): liquid oil, -Ingredients (D): Surfactin sodium and -Component (E): Water phase The use of a cosmetic composition containing, The total amount of component (A) and component (B) is 1 to 15% by mass of the total mass of the cosmetic composition. The mass ratio of component (C) to the total amount of components (A) and (B) ((C) / (A)+(B)) is 0.05 to 0.4. Components (A) and (B) have a mixed HLB of 12.4 to 14.2. This invention relates to the use of a cosmetic composition for removing blackheads, wherein the total amount of component (D) is 0.2 to 2.5% by mass of the total mass of the cosmetic composition.

[0014] The inventors have discovered that a specific combination of components in an aqueous composition makes it possible to provide a PEG-free cleansing composition for removing blackheads that is completely non-irritating to the skin and more environmentally friendly.

[0015] By adding specific surfactants, such as sodium surfactant and polyglycerin derivatives, together with the aqueous and liquid oil phases, and ensuring that each component is present in a specific ratio, improved cleansing performance was achieved through spontaneous emulsification while ensuring reduced skin irritation, thereby removing keratin plugs.

[0016] In particular, within the scope of the present invention, the aqueous composition (sometimes used synonymously with aqueous composition) is a double continuous microemulsion (BCME) that has excellent cleansing ability despite a higher aqueous phase content. The higher aqueous phase content is understood as an aqueous composition containing at least 75% by mass, preferably at least 83% by mass, and preferably 88% by mass, of the total mass of the composition. For example, this is understood as at least 75% by mass, preferably at least 88% by mass, of water alone, or a combination of water and a water-soluble component, based on the total mass of the composition. The BCME can be obtained by a cold process, meaning that the aqueous phase, which constitutes the majority of the composition, can be used at room temperature. Nevertheless, other components forming the BCME may be preheated. Room temperature is understood as a temperature of 20-25°C.

[0017] The composition may be highly fluid. The composition may have a viscosity of less than 100 mPas, preferably 1 to 80 mPas. Alternatively, the composition may be a gel and may have a viscosity of more than 1000 mPas, preferably 5000 mPas to 30000 mPas, preferably 5000 mPas to 20000 mPas, and preferably about 10000 mPas.

[0018] BCME may have a unique behavior of interacting spontaneously with the oil layer to form an emulsion. This enables more efficient removal of comedones compared to common cleansing agents that act at the interface of the cleansing agent and oil alone. Thus, the aqueous composition uses a surfactant, sodium surfactin, and thus does not contain polyethylene oxide and / or polypropylene oxide.

[0019] In contrast to normal micelles and emulsions containing an outer phase and an inner phase, BCME does not have such separate phases. The specific composition of the aqueous composition inhibits physical stimuli such as friction and enables self-emulsification that reduces skin stress during cleansing.

[0020] In fact, bicontinuous microemulsion (BCME) has a complex three-dimensional structure of a bicontinuous aqueous phase and surfactant / oil, with low interfacial tension and high solubilization power. Thus, BCME has a high cleansing ability because it can easily contact the comedones and remove them. By applying this bicontinuous microemulsion, rapid, high-level comedone removal from the skin, as well as makeup removal, can be achieved without stressing the skin.

[0021] With reference to the accompanying drawings, the present disclosure can be better understood, and many of its features and advantages can become apparent to those skilled in the art.

Brief Description of the Drawings

[0022] [Figure 1] Figure 1 is a photograph obtained by cryo FIB-SEM performed with the composition of Example 1A according to the present invention. [Figure 2] Figures 2A-2F are photographs obtained for the contact surfaces of artificial comedones (Figures 2A, 2C, 2E) and artificial sebum (Figures 2B,​​Figures 3A-3C are photographs obtained by microscopic observation (200-fold magnification) of the contact surfaces of an artificial comedone with each of the cleansing compositions of Example 1A (Figure 3A), Example 1B (Figure 3B), and Example 1C (Figure 3C) according to the present invention. [Figure 3B] Figures 3A-3C are photographs obtained by microscopic observation (200-fold magnification) of the contact surfaces of an artificial comedone with each of the cleansing compositions of Example 1A (Figure 3A), Example 1B (Figure 3B), and Example 1C (Figure 3C) according to the present invention. [Figure 3C] Figures 3A-3C are photographs obtained by microscopic observation (200-fold magnification) of the contact surfaces of an artificial comedone with each of the cleansing compositions of Example 1A (Figure 3A), Example 1B (Figure 3B), and Example 1C (Figure 3C) according to the present invention.

Mode for Carrying Out the Invention

[0023] The cosmetic composition for removing comedones according to the present invention comprises the following components (A) to (E): - Component (A): A polyglycerol fatty acid ester made from a fatty acid having 8 carbon atoms and polyglycerol having a glycerin polymerization degree of 5 to 7, - Component (B): A polyglycerol fatty acid ester made from a fatty acid having 10 carbon atoms and polyglycerol having a glycerin polymerization degree of 5 to 7, - Component (C): A liquid oil, - Component (D): Sodium surfactin and - Component (E): An aqueous phase and The total amount of component (A) and component (B) is 1 to 15% by mass of the total mass of the cosmetic composition, The mass ratio of component (C) to the total amount of components (A) and (B) ((C) / (A)+(B)) is 0.05 to 0.4, Components (A) and component (B) have a mixed HLB of 12.4 to 14.2, The total amount of component (D) is 0.2 to 2.5% by mass of the total mass of the cosmetic composition.

[0024] Component (A) Component (A) is an ester made from a fatty acid having eight carbon atoms and glycerol with a degree of polymerization of 5 to 7, preferably 6.

[0025] Ingredient (B) Component (B) is a diester made from a fatty acid having 10 carbon atoms and polyglycerin having a degree of polymerization of 5 to 7, preferably 6, of glycerol.

[0026] Polyglycerol fatty acid esters can be easily obtained by conventional methods of esterification of polyglycerol and fatty acids, or by addition polymerization of fatty acids and glycidol. Esterification of polyglycerol and fatty acids can be carried out, for example, by heating polyglycerol and fatty acids at a temperature range of preferably 100°C to 300°C, more preferably 120°C to 260°C, in the presence of an acid catalyst (such as phosphoric acid or p-toluenesulfonic acid) or an alkaline catalyst (such as sodium hydroxide), or in the absence of a catalyst, while removing water, but is not particularly limited to these methods. In addition, the reaction can be carried out in the presence of an inert gas. The esters obtained as described above can be purified according to their purpose. For purification, distillation techniques such as distillation under reduced pressure, molecular distillation, or steam distillation can be used, as well as extraction with organic solvents, fractionation, or chromatographic separation using a column packed with synthetic adsorbents or gel filters. Polyglycerol fatty acid esters referred to here can be obtained by transesterification with polyglycerol using fatty acid esters instead of fatty acids.

[0027] The total amount of component (A) and component (B) is 1 to 15% by mass of the total mass of the cosmetic composition, preferably 2 to 10% by mass, preferably 3 to 5% by mass, 2 to 4% by mass in the first preferred embodiment, 4 to 6% by mass in the second preferred embodiment, and 10 to 15% by mass in the third preferred embodiment. In addition, the mixed HLB of component (A) and component (B) is 12.4 to 14.2, preferably 13 to 14.

[0028] As used herein, HLB refers to the value measured by the Griffin calculation method shown below, and the mixed HLB of component (A) and component (B) is calculated by utilizing their additivity. Specifically, as used herein, the mixed HLB is the weighted average of component (A) and component (B). HLB=20(1-S / A); in the formula, S: Saponification value of polyglycerol fatty acid ester, and A: Neutralization value of raw fatty acids.

[0029] Ingredients (C) Component (C) is a liquid oil. Examples of liquid oils include hydrocarbon oils, ester oils, acylglycerols, ether oils, vegetable oils, and silicone oils. Ester oils are preferred from the viewpoint of stickiness.

[0030] Examples of hydrocarbon oils include hydrogenated polyisobutene, liquid paraffin, light liquid isoparaffin, squalane, undecane, and tridecane.

[0031] Examples of ester oils include isononyl isononanoate, isostearyl isostearate, cetyl 2-ethylhexanoate, ethylhexyl palmitate, octyldodecyl myristate, isopropyl myristate, propylheptyl caprylate, caprylate / caprylate caprylate, caprylate / caprylate caprylate, and dicaprylate carbonate.

[0032] Examples of acylglycerols include tri(caprylic / capric acid) glyceryl, tri-2-ethylhexanoic acid, glyceryl triisostearate, and glyceryl diisostearate.

[0033] Examples of vegetable oils include camellia oil, avocado oil, almond oil, olive oil, wheat germ oil, rice germ oil, rice bran oil, safflower oil, soybean oil, corn oil, rapeseed oil, palm kernel oil, castor oil, sunflower oil, jojoba oil, macadamia nut oil, and coconut oil.

[0034] The total content of component (C) is 0.15% to 1.2% by mass of the total mass of the cosmetic composition, preferably 0.5% to 1%.

[0035] The mass ratio of component (C) to the total amount of components (A) and (B) (expressed as (C) / [(A)+(B)]) is 0.05 to 0.4, preferably 0.25 to 0.35.

[0036] Ingredients (D) Sodium surfactin is a naturally occurring anionic surfactant with high biodegradability. It is a peptide lipid composed of amino acids and fatty acids, produced by the fermentation of Bacillus subtilis. However, due to its unique structure, it can be somewhat unstable over time. Adding sodium surfactin together with other ingredients achieves both selective cleaning power and stability.

[0037] Furthermore, self-emulsification does not occur in BCME formulations that do not contain sodium surfactant. Through self-emulsification, oil impurities are not only solubilized but rather emulsified. Within the scope of the present invention, emulsification can incorporate a larger amount of impurities than solubilization.

[0038] The content of component (D) is 0.2% to 2.5% by mass of the total mass of the cosmetic composition.

[0039] Ingredient (E) Component E is an aqueous phase containing water, and may optionally contain other components constituting the aqueous phase, such as water-soluble components that do not exhibit surfactant properties. The aqueous phase may optionally contain water and humectants (e.g., sorbitol), thickeners or gelling agents (e.g., acrylates / alkyl alkynyl (C10-30) crosspolymer), polysaccharides (e.g., xanthan gum), alkaline agents acting as neutralizing agents (e.g., sodium hydroxide or tromethamine), preservatives (e.g., chlorphenesin), etc. In one embodiment, the aqueous phase (component E) may consist only of water, such as deionized water or floral water such as camellia water, or a mixture thereof.

[0040] The content of component (E) may be at least 75% by mass of the total mass of the composition, preferably at least 83% by mass or more, preferably 88% by mass of the aqueous phase, for example, it may contain at least 75% by mass, preferably at least 83% by mass or more, preferably at least 88% by mass of water alone, or a combination of water and a water-soluble component.

[0041] Ingredients (F) The cosmetic composition may further contain a hydrophilic nonionic surfactant as component (F) in an amount of 0.01 to 1.0% by mass, preferably 0.1 to 0.5%, of the total mass of the cosmetic composition.

[0042] Component (F) may be a polyglycerol alkyl ether. The alkyl can be selected from an alkyl chain containing 6 to 20 carbon atoms, preferably 10 to 14 carbon atoms.

[0043] Double continuous microemulsion (BCME) Both continuous microemulsions and oil-in-water microemulsions have different structures. In the case of BCME, a classical microemulsion is a so-called swollen micelle containing a small amount of oil. The outer phase is the aqueous phase, and the inner phase is the oil phase. Thermodynamically, when oil is added to a stable single liquid phase, it floats on the liquid surface without diffusing into the inner phase. On the other hand, BCME has neither an inner nor an outer phase. They are independent and form a continuous phase. Therefore, BCME has a sponge-like structure. As a result, when the aqueous phase and / or oil are added, they can diffuse through each continuous region. Using this property, BCME is commonly identified by a method called the dye method. When dyed oil and dyed aqueous phase are added simultaneously, BCME diffuses both. In classical microemulsions, the dyed aqueous phase diffuses, but the dyed oil floats.

[0044] Previously, BC structures were observed using methods such as FF-TEM, but cryo-FIB-SEM, which can remove volatile components such as water through sublimation, has made it possible to obtain clearer images.

[0045] Both continuous microemulsions do not form particles, and therefore their particle size cannot be measured.

[0046] Both continuous structures were demonstrated by SAXS and cryo-FIB-SEM. Cryo-FIB-SEM is used because this method allows for the removal of volatile components such as water by sublimation, enabling the acquisition of clearer images, as shown in Figure 1.

[0047] Figure 1 is a photograph obtained by cryo-FIB-SEM performed on the composition of Example 1 according to the present invention (see Table 2, Example 1). The photograph captures two regions: (a): Shows the surface condition after cryogenic treatment with liquid nitrogen followed by sublimation treatment. (b): Shows the surface condition after cryogenic treatment with liquid nitrogen, followed by surface abrasion with FIB, and then sublimation treatment. The black areas in region (b) indicate components that have volatilized due to sublimation. In this case, it is likely water. The white-gray areas are where oil and surfactants are present.

[0048] Furthermore, two formulations (BCME-SF and BCME-0), one containing and one without surfactant sodium, were used in all measurements. The BCME structure was identified by SAXS and cryo-FIB-SEM (not shown).

[0049] SAXS and cryo-FIB-SEM demonstrated that BCME containing sodium surfactant has a sponge-like structure in which large amounts of water are trapped in a flexible two-layer network of surfactants. Two-layer structures with zero curvature are generally known to achieve lower interfacial tension (γ).

[0050] Conventional water-based cleansing agents remove makeup by solubilization, but BCME behaves in the opposite way. When in contact with an oil layer, BCME preferentially adopts a negative curvature rather than a positive one, allowing it to penetrate the oil layer. This dynamic change in curvature may be caused by the affinity between the hydrophobic chains of the oil and the surfactant, which may be related to the interfacial energy. Thus, the inventors have succeeded in developing a new, stable formulation containing surfactin that can remove keratin plugs from the skin.

[0051] The cosmetic composition may contain at least one common additive in the art, such as at least one compound selected from emollients or humectants, oils, surfactants, colorants, preservatives, antioxidants, surfactants, organic or inorganic powders, sunscreens, and fragrances.

[0052] - One or more humectants such as polyols (glycerin, diglycerin, propylene glycol, propanediol, caprylyl glycol, pentylene glycol, butylene glycol, hexanediol, sorbitol, maltitol), sugars, glycosaminoglycans such as hyaluronic acid and its salts and esters, and polyquaternium such as Lipidure PMB.

[0053] The humectant may be present in the composition in an amount ranging from about 0.1% to about 30% by weight, preferably about 0.005% to about 10% by weight, relative to the total weight of the composition.

[0054] The aforementioned humectant is preferably sorbitol. By adding sorbitol to the composition in an amount ranging from about 15% to about 30% by weight relative to the total weight of the composition, sorbitol functions as a texture modifier and enhances the pleasant feel of the composition. Preferably, the composition is in the form of a cleansing massage gel. Sorbitol does not have a direct effect on the removal of blackheads, but it does have an indirect effect. Sorbitol enhances the rich feel of the composition and makes massaging with the composition more pleasant.

[0055] - One or more alcohols, such as linear or branched monoalcohols containing 1 to 6 carbon atoms, that are in liquid form at room temperature (25°C). Preferably, the alcohol is ethanol, propanol, butanol, isopropanol, isobutanol, pentanol, hexanol, or a mixture thereof. More preferably, the alcohol is ethanol. The alcohol may be present in the composition in an amount ranging from about 0.1% to about 10% by weight relative to the total weight of the composition.

[0056] - For example, one or more emollients that can be selected from jojoba esters, esters of fatty acids and fatty alcohols (octyldodecyl myristate, triethylhexanoin, dicaprylyl carbonate, isostearyl isostearate, caprylic / capric triglyceride), shea butter (butyrospernum parkii butter extract, shea butter ethyl ester, marketed under the trade names LIPEX SHEASOFT, LIPEX SHEA-U, LIPEX SHEA, LIPEX SHEALIGHT, LIPEX SHEA TRIS) or moringa (moringa oil / hydrogenated moringa oil ester), waxes (acacia decurrens flower wax & helianthus annuus cera seed wax, C10-18 triglycerides), vegetable oils, phytosqualane, and alkanes (undecane, tridecane).

[0057] The skin emollient may be present in the composition in an amount ranging from about 0.1% to about 30% by weight, preferably about 0.5% to about 10% by weight, relative to the total weight of the composition.

[0058] -One or more film-forming agents, such as naturally occurring polymers that may be modified, may be selected from shellac resin, sandarac rubber, gum arabic (Acacia senegal gum), dammar, elemis, copal, cellulose polymer, polymers extracted from the fruit of Caesalpinia spinosa and / or the alga Kappaphycus alvarezii (such as product Filmexel®), and mixtures thereof.

[0059] The film-forming agent may be present in the composition in an amount ranging from about 0.1% to about 15% by weight, preferably about 0.5% to about 10% by weight, relative to the total weight of the composition.

[0060] - One or more colorants selected from pigments, pearlescent pigments, and preferably water-soluble dyes. Pigments may be white or colored minerals and / or organic substances. Mineral pigments may be selected from zirconium oxide or cerium oxide, and zinc oxide, iron oxide or chromium oxide, and titanium dioxide. Pearlescent pigments may be selected from titanium mica coated with iron oxide, titanium mica coated with bismuth oxychloride, titanium mica coated with chromium oxide, titanium mica coated with organic dyes, and pearlescent pigments based on bismuth oxychloride. Water-soluble dyes may be selected from FDC Red 4, DC Red 6, DC Red 22, DC Red 28, DC Red 30, DC Red 33, DC Orange 4, DC Yellow 5, DC Yellow 6, DC Yellow 8, FDC Green 3, DC Green 5, and FDC Blue 1.

[0061] The coloring agent may be present in the composition in an amount ranging from about 0.01% to about 20% by weight, preferably about 1% to about 15% by weight, relative to the total weight of the composition.

[0062] - One or more fillers selected from lauroyl-lysine, starch, boron nitride, and silica.

[0063] The filler may be present in the composition in an amount ranging from about 0.1% to about 10% by weight, preferably about 0.5% to about 7% by weight, relative to the total weight of the composition.

[0064] - For example, vitamin C and its derivatives (ascorbyl glucoside, 3-o-ethyl ascorbic acid, tetraisopalmitate ascorbyl), vitamin A and its derivatives, vitamin E and its derivatives, vitamins such as vitamin B3 or niacinamide, panthenol, oligo-elements, allantoin, adenosine, peptides (marketed under the trademarks NP RIGIN, MATRIXYL 3000, IDEALIFT, EYESERYL, including palmitoyl tetrapeptide-7, palmitoyl tripeptide-1, palmitoyl pentapeptide-4, acetyl dipeptide-1 cetyl ester, acetyl tetrapeptide-5), plant extracts (Glycyrrhiza glabra extract, Centella asiatica leaf extract, rye extract) One or more activators of natural, biotechnological, or synthetic origin that are bioactive and have efficacy on the skin via biological sites, selected from cereal (seed extract), yeast extract, alpha hydroxy acids such as glycolic acid or lactic acid, tranexamic acid and its derivatives such as cetyl tranexamic acid ester.

[0065] The activator may be present in the composition in an amount ranging from about 0.01 to about 10% by weight, preferably about 0.1 to about 5% by weight, relative to the total weight of the composition.

[0066] - One or more alkaline agents selected herein that act as neutralizing agents, including tromethamine (tris,2-amino-2-(hydroxymethyl)propane-1,3-diol, CAS 77-86-1), alkali metal hydroxides (such as sodium hydroxide) or alkaline earth metal hydroxides, amines such as triethanolamine, and basic amino acids such as arginine.

[0067] The alkaline agent acting as a neutralizing agent in this specification may be present in the composition in an amount ranging from about 0.01 to about 5% by weight, preferably about 0.1 to about 3% by weight, relative to the total weight of the composition.

[0068] The alkaline agent is preferably Tris. The alkaline agent may be added as a neutralizing agent for the acrylic acid polymer. When added, the composition preferably takes the form of a cleansing massage gel, obtaining a resilient, soft gel texture.

[0069] - One or more thickeners or gelling agents in the aqueous phase, cellulose derivatives (such as hydroxyethylcellulose, sodium carboxymethylcellulose, hydroxypropylmethylcellulose, hydroxypropylcellulose, ethylcellulose, and hydroxymethylcellulose), gums (such as xanthan gum, guar, carob, locust bean, alginate, carrageenan, sclerotium, etc.), clay (laponite), hydrophilic or amphiphilic crosslinked or non-crosslinked homopolymers and copolymers of acryloylmethylpropanesulfonic acid (AMPS) and / or acrylamide and / or acrylic acid and / or salts or esters of acrylic acid (such as ammonium AMP / VP copolymer, hydroxyethyl acrylate / AMPS copolymer, sodium acrylate / AMPS copolymer, acrylamide / AMPS copolymer, acrylate copolymer, acrylates / alkyl (C10-30) acrylate crosspolymer, carbomer, polyacrylate crosspolymer-6, sodium polyacrylate, etc.).

[0070] The aqueous thickener or gelling agent may be present in the composition in an amount ranging from about 0.01 to about 10% by weight, preferably about 0.1 to about 5% by weight, relative to the total weight of the composition.

[0071] Other additives commonly used in cosmetics, particularly preservatives, antioxidants, or fragrances well known in this art, may also be present in the compositions according to the present invention.

[0072] - One or more antimicrobial agents, such as chlorphenesin, may be added.

[0073] The antimicrobial agent may be present in the composition in an amount ranging from about 0.01 to about 3% by weight, preferably about 0.1 to about 1% by weight, relative to the total weight of the composition.

[0074] According to one embodiment, the cosmetic composition for removing blackheads according to the present invention comprises the following components (A) to (E): -Component (A): Polyglycerin fatty acid ester made from a fatty acid having 8 carbon atoms and polyglycerin having a glycerin polymerization degree of 5-7. -Component (B): Polyglycerin fatty acid ester made from a fatty acid having 10 carbon atoms and polyglycerin having a glycerin polymerization degree of 5-7. -Component (C): liquid oil, -Component (D): Surfactin sodium and -Component (E): Water phase Includes, The total amount of component (A) and component (B) is 2 to 4% by mass of the total mass of the cosmetic composition. The mass ratio of component (C) to the total amount of components (A) and (B) ((C) / (A)+(B)) is 0.05 to 0.4. Components (A) and (B) have a mixed HLB of 12.4 to 14.2. The total amount of component (D) is 0.2 to 2.5% by mass of the total mass of the cosmetic composition.

[0075] According to one embodiment, the cosmetic composition for removing blackheads according to the present invention comprises the following components (A) to (E): -Component (A): Polyglycerin fatty acid ester made from a fatty acid having 8 carbon atoms and polyglycerin having a glycerin polymerization degree of 5-7. -Component (B): Polyglycerin fatty acid ester made from a fatty acid having 10 carbon atoms and polyglycerin having a glycerin polymerization degree of 5-7. -Component (C): liquid oil, -Component (D): Surfactin sodium and -Component (E): Water phase Includes, The total amount of component (A) and component (B) is 4 to 6% by mass of the total mass of the cosmetic composition. The mass ratio of component (C) to the total amount of components (A) and (B) ((C) / (A)+(B)) is 0.05 to 0.4. Components (A) and (B) have a mixed HLB of 12.4 to 14.2. The total amount of component (D) is 0.2 to 2.5% by mass of the total mass of the cosmetic composition. Ingredient (E) contains sorbitol.

[0076] According to one embodiment, the cosmetic composition for removing blackheads according to the present invention comprises the following components (A) to (E): -Component (A): Polyglycerin fatty acid ester made from a fatty acid having 8 carbon atoms and polyglycerin having a glycerin polymerization degree of 5-7. -Component (B): Polyglycerin fatty acid ester made from a fatty acid having 10 carbon atoms and polyglycerin having a glycerin polymerization degree of 5-7. -Component (C): liquid oil, -Component (D): Surfactin sodium and -Component (E): Water phase Includes, The total amount of component (A) and component (B) is 10 to 15% by mass of the total mass of the cosmetic composition. The mass ratio of component (C) to the total amount of components (A) and (B) ((C) / (A)+(B)) is 0.05 to 0.4. Components (A) and (B) have a mixed HLB of 12.4 to 14.2. The total amount of component (D) is 0.2 to 2.5% by mass of the total mass of the cosmetic composition.

[0077] Those skilled in the art can select from all of these possible additives both in terms of properties and quantity to be added to the composition, such that the composition retains all of its characteristics.

[0078] Cosmetic compositions may be transparent.

[0079] The above cosmetic composition may be a cleansing cosmetic composition.

[0080] By applying the composition through massage, blackheads are more exposed to the composition and removed more efficiently.

[0081] The cosmetic composition may be a makeup cleansing product for the skin, more preferably a makeup cleansing product for the body and / or face. The cosmetic composition may be selected from cleansing water, concentrated cleansing water, or cleansing gel, preferably a body and / or face cleansing massage gel. [Examples]

[0082] [Example 1A] Process for preparing the cosmetic composition of the present invention (cleansing water composition)

[0083] [Table 1]

[0084] [Example 1B] Process for preparing the cosmetic composition of the present invention (concentrated cleansing composition)

[0085] [Table 2]

[0086] [Example 1C] Process for preparing the cosmetic composition of the present invention (massage gel cleansing composition)

[0087] [Table 3]

[0088] [Example 2] Effectiveness against blackheads Artificial keratin plugs were prepared according to the following composition.

[0089] Composition of artificial keratin plugs: 50% by weight of artificial sebum and 50% by weight of keratin powder relative to the total weight of the artificial keratin plugs.

[0090] Composition of artificial sebum: 48% by weight of soybean oil, 13% by weight of oleic acid, 12% by weight of myristic acid, 12% by weight of squalene, 10% by weight of paraffin wax, 3% by weight of oleic acid monoglyceride, and 2% by weight of cholesterol stearate, based on the total weight of artificial keratin sebum.

[0091] Using two methods, the degradation of artificial keratin plugs in the presence of each of the compositions in Examples 1A, 1B, and 1C was observed.

[0092] Method 1: Observation of the contact surface between artificial sebum and artificial comedones and the cleansing composition. - Heat the artificial sebum and artificial keratin plugs separately to 70°C, place 3g of each into separate glass bottles, and let them cool overnight at 5°C. Place 5g of the cleansing composition of Example 1B into each bottle and close the lid. - Leave it at 37°C, shake it 10 times each time (initial, after 3 hours, and after 12 hours), and then take a photograph of its appearance.

[0093] Figures 2A, 2C, and 2E are photographs obtained from the contact surface between the artificial comedone and the cleansing composition of Example 1B according to the present invention at three different times: at initial contact, 3 hours later, and 12 hours later.

[0094] Figures 2B, 2D, and 2F are photographs obtained from the contact surface between artificial sebum and the cleansing composition of Example 1B according to the present invention at three different times: at initial contact, 3 hours later, and 12 hours later.

[0095] When the cleansing composition comes into contact with each dirt model, the composition penetrates the dirt model (both artificial sebum and artificial keratin plugs) due to its BCME structure and breaks down the solid. In particular, it was observed that the artificial keratin plugs dispersed within the cleansing composition.

[0096] Method 2: Microscopic observation of the contact surface between the artificial keratin plug and the cleansing composition. -- Heat the artificial keratin plug to 70°C, drop one drop onto a microscope slide, and let it cool at room temperature. - Crush it with the cover glass. - To ensure that the artificial keratin plug has sufficient contact space with the cleansing composition, two additional 0.15 mm thick cover glasses are used as spacers between the slide glass and the cover glass, placed on both ends of a drop of artificial keratin plug. -0.2 mL of the cleansing composition is injected through the side of the coverslip. - Microscopic observation at room temperature (200x magnification). *Digital microscope (VHX-6000 / KEYENCE)

[0097] The composition of Example 1A was observed to quickly penetrate the artificial keratin plug and form an emulsion (Figure 3A).

[0098] The composition of Example 1B was observed to quickly penetrate and scrape off the artificial keratin plugs. In particular, the artificial keratin plugs were observed to swell and decompose from within (Figure 3B).

[0099] The composition of Example 1C did not penetrate quickly due to its higher viscosity, but it was observed to form an emulsion similar to that of the composition of Example 1A. The artificial keratin plugs easily disintegrated with slight movement (Figure 3C).

[0100] Further research was conducted using human comedones. Comedones were collected using pore patch removal. Using a microtome, the removed comedones were thinly sliced ​​and crushed, and their cross-sections were observed under a microscope, similar to the artificial comedones described in Method 2 above.

[0101] Similar to artificial keratin plugs, the cleansing compositions of Examples 1A and 1B penetrated quickly, and not only was the disintegration of keratin plugs observed, but emulsion formation was also seen. The cleansing composition of Example 1C was also observed to efficiently disintegrate keratin plugs.

Claims

1. The following components (A) to (E): Component (A): Polyglycerin fatty acid ester made from a fatty acid having 8 carbon atoms and polyglycerin having a degree of polymerization of 5 to 7 degrees of glycerin. Component (B): Polyglycerin fatty acid ester made from a fatty acid having 10 carbon atoms and polyglycerin having a degree of polymerization of 5 to 7 degrees of glycerin. Component (C): liquid oil, Ingredient (D): Surfactin sodium and Component (E): water phase The use of a cosmetic composition for removing blackheads, including, The total amount of component (A) and component (B) is 1 to 15% by mass of the total mass of the cosmetic composition. The mass ratio of component (C) to the total amount of components (A) and (B) ((C) / (A)+(B)) is 0.05 to 0.

4. Component (A) and component (B) have a mixed HLB of 12.4 to 14.

2. The use of a cosmetic composition in which the total amount of component (D) is 0.2 to 2.5% by mass of the total mass of the cosmetic composition.

2. The use of the cosmetic composition according to claim 1, wherein the content of component (E) is 75% by mass or more, preferably 88.5% by mass or more, of the total mass of the cosmetic composition.

3. Use of the cosmetic composition according to claim 1 or 2, further comprising a hydrophilic nonionic surfactant as component (F) in an amount of 0.01 to 1.0% by mass of the total mass of the cosmetic composition.

4. Use of the cosmetic composition according to claim 3, wherein the component (F) is a polyglycerin alkyl ether.

5. Use of the cosmetic composition according to claim 4, wherein the alkyl is selected from an alkyl chain containing 6 to 20 carbon atoms, preferably 10 to 14 carbon atoms.

6. Use of the cosmetic composition according to any one of claims 1 to 5, wherein the total content of component (C) is 0.15 to 1.2% by mass of the total mass of the cosmetic composition.

7. Use of the cosmetic composition according to any one of claims 1 to 6, wherein the total amount of component (A) and component (B) is 4 to 6% by mass of the total mass of the cosmetic composition.

8. Use of the cosmetic composition according to any one of claims 1 to 6, wherein the total amount of component (A) and component (B) is 10 to 15% by mass of the total mass of the cosmetic composition.

9. Use of the cosmetic composition according to any one of claims 1 to 8, wherein the component (E) contains sorbitol.

10. Use of the cosmetic composition according to any one of claims 1 to 9, which is transparent.

11. Use of the cosmetic composition according to any one of claims 1 to 10, which is a cleansing cosmetic composition.

12. Use of the cosmetic composition according to claim 11, which is a makeup cleansing product for the skin, more preferably a makeup cleansing product for the body and / or face.

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