Liquid pesticide composition

Abstract

The present invention provides a liquid pesticide composition containing iminoctadine albesilate, which suppresses the formation of aggregates and inhibits the increase in particle size during low-temperature storage. [Solution] A liquid pesticide composition containing iminoctadine albesilate, dodecane-1-ol, aliphatic higher alcohol alkoxylate, and sorbitan fatty acid ester.

Description

Technical Field

[0001] The present invention relates to a liquid pesticide composition.

Background Art

[0002] Patent Documents 1 and 2 disclose aqueous suspension pesticide formulations containing iminoctadine albesilate. More specifically, Patent Document 1 describes that by blending iminoctadine albesilate with a specific alcohol or phospholipid, a surfactant having an alkyl or alkenyl group with 6 to 20 carbon atoms, and water, an aqueous suspension pesticide formulation can be obtained that maintains a stable suspension state and has no crystal precipitation of iminoctadine albesilate under storage conditions where the temperature changes greatly (in the range of 50°C to -10°C) over a long period. However, the formulation described in Patent Document 1 was not sufficiently storage-stable under storage conditions where the temperature changes slightly (in the range of 5°C to -10°C) over a short period. Therefore, in Patent Document 2, it is described that by using a hydrogenated phospholipid having an iodine value of 20 or less as the phospholipid in the formulation described in Patent Document 1, a stable suspension state can be maintained and crystal precipitation of iminoctadine albesilate can be suppressed even under such storage conditions.

Prior Art Documents

Patent Documents

[0003]

Patent Document 1

Patent Document 2

Summary of the Invention

Problems to be Solved by the Invention

[0004] As mentioned above, while conventional aqueous suspension pesticide formulations containing iminoctadine albesilate had excellent storage stability, there was still room for improvement in terms of suppressing the generation of aggregates during manufacturing and low-temperature storage, as well as changes in the particle size of iminoctadine albesilate.

[0005] The present invention aims to provide a liquid pesticide composition containing iminoctadine albesilate, which suppresses the generation of aggregates and inhibits the increase in particle size during low-temperature storage. [Means for solving the problem]

[0006] The present invention provides the following liquid pesticide compositions. [1] A liquid pesticide composition containing iminoctadine albesilate, dodecane-1-ol, aliphatic higher alcohol alkoxylate, and sorbitan fatty acid ester. [2] The liquid pesticide composition according to [1], wherein the dodecane-1-ol content is 0.75% by mass or more and 6% by mass or less. [3] The liquid pesticide composition according to [1] or [2], wherein the mass ratio of iminoctadine albesilate to dodecane-1-ol is 100:10 to 100:50. [4] A liquid pesticide composition according to any one of [1] to [3], wherein the mass ratio of aliphatic higher alcohol alkoxylate to sorbitan fatty acid ester is 3:1 to 1:3. [5] A liquid pesticide composition according to any one of items [1] to [4], wherein the viscosity at 10℃ is 4000 mPa·s or less. [Effects of the Invention]

[0007] According to the present invention, it is possible to provide a liquid pesticide composition containing iminoctadine albesilate, in which the generation of aggregates is suppressed and the increase in particle size during low-temperature storage is suppressed. [Modes for carrying out the invention]

[0008] This liquid pesticide composition contains iminoctadine albesilate.

[0009] The amount of iminoctadine albesilate in this liquid pesticide composition is usually 1 part by mass or more and 30 parts by mass or less per 100 parts by mass of this liquid pesticide composition, preferably 5 parts by mass or more and 20 parts by mass or less, more preferably 8 parts by mass or more and 15 parts by mass or less, and even more preferably 10 parts by mass or more and 12 parts by mass or less.

[0010] In this liquid pesticide composition, iminoctadine albesilate is dispersed in water in the form of oil droplets.

[0011] This liquid pesticide composition contains dodecane-1-ol, aliphatic higher alcohol alkoxylate, and sorbitan fatty acid ester (hereinafter, each of these three components will also be referred to as the surfactant).

[0012] The dodecane-1-ol content in this liquid pesticide composition is usually 0.1 parts by mass or more and 10 parts by mass or less per 100 parts by mass of the liquid pesticide composition, preferably 0.75 parts by mass or more and 6 parts by mass or less, and more preferably 0.75 parts by mass or more and 4 parts by mass or less.

[0013] In this liquid pesticide composition, the mass ratio of iminoctadine albesilate to dodecane-1-ol (iminoctadine albesilate:dodecane-1-ol) is usually 100:2 to 100:100, preferably 100:5 to 100:80, and more preferably 100:10 to 100:50.

[0014] Aliphatic higher alcohol alkoxylates are obtained by adding an alkylene oxide to an aliphatic higher alcohol. In this specification, "higher" means having 8 to 20 carbon atoms. The aliphatic higher alcohol may be a primary alcohol, a secondary alcohol, or a tertiary alcohol. The degree of alkoxylation of the aliphatic higher alcohol alkoxylate may be 1 to 50, 5 to 25, or 5 to 15. Examples of aliphatic higher alcohol alkoxylates include aliphatic higher alcohol ethoxylates and aliphatic higher alcohol propoxylates. One or more aliphatic higher alcohol alkoxylates may be used.

[0015] Aliphatic higher alcohol alkoxylates have hydrocarbon groups derived from aliphatic higher alcohols. The number of carbon atoms in the hydrocarbon group is 8 to 20, and may be 10 to 20, 12 to 20, 14 to 20, or 16 to 20. Aliphatic higher alcohol alkoxylates may be aliphatic primary higher alcohol alkoxylates, aliphatic secondary higher alcohol alkoxylates, or aliphatic tertiary higher alcohol alkoxylates. Specific examples of aliphatic higher alcohol alkoxylates include, for example, lauryl alcohol ethoxylate, myristyl alcohol ethoxylate, cetyl alcohol ethoxylate, palmityl alcohol ethoxylate, isostearyl alcohol ethoxylate, stearyl alcohol ethoxylate, oleyl alcohol ethoxylate, lauryl alcohol propoxylate, myristyl alcohol propoxylate, cetyl alcohol propoxylate, palmityl alcohol propoxylate, isostearyl alcohol propoxylate, stearyl alcohol propoxylate, and oleyl alcohol propoxylate. One or more aliphatic higher alcohol alkoxylates can be used.

[0016] The aliphatic higher alcohol alkoxylate content in this liquid pesticide composition is usually 0.1 parts by mass or more and 10 parts by mass or less per 100 parts by mass of the liquid pesticide composition, preferably 0.5 parts by mass or more and 5 parts by mass or less, and more preferably 0.5 parts by mass or more and 3 parts by mass or less.

[0017] In this liquid pesticide composition, the mass ratio of iminoctadine albesilate to aliphatic higher alcohol alkoxylate (iminoctadine albesilate:aliphatic higher alcohol alkoxylate) is usually 100:1 to 100:100, preferably 100:2 to 100:50, and more preferably 100:4 to 100:25.

[0018] Examples of sorbitan fatty acid esters include sorbitan laurate, sorbitan stearate, sorbitan oleate, and sorbitan trioleate. The sorbitan fatty acid ester may be a polyoxyalkylene sorbitan fatty acid ester to which alkylene oxide has been added, but it is preferable that it is a sorbitan fatty acid ester without added alkylene oxide. Examples of polyoxyalkylene sorbitan fatty acid esters include polyoxyethylene sorbitan laurate, polyoxyethylene sorbitan stearate, polyoxyethylene sorbitan oleate, and polyoxyethylene sorbitan trioleate. One or more types of sorbitan fatty acid esters can be used.

[0019] The sorbitan fatty acid ester content in this liquid pesticide composition is usually 0.1 parts by mass or more and 10 parts by mass or less per 100 parts by mass of the liquid pesticide composition, preferably 0.5 parts by mass or more and 5 parts by mass or less, and more preferably 0.5 parts by mass or more and 3 parts by mass or less.

[0020] In this liquid pesticide composition, the mass ratio of iminoctadine albesilate to sorbitan fatty acid ester (iminoctadine albesilate: sorbitan fatty acid ester) is usually 100:1 to 100:100, preferably 100:2 to 100:50, and more preferably 100:4 to 100:25.

[0021] In this liquid pesticide composition, the mass ratio of dodecan-1-ol to aliphatic higher alcohol alkoxylate (dodecan-1-ol: aliphatic higher alcohol alkoxylate) is usually 10:1 to 1:10, preferably 8:1 to 1:8, and more preferably 4:1 to 1:4.

[0022] In this liquid pesticide composition, the mass ratio of dodecan-1-ol to sorbitan fatty acid ester (dodecan-1-ol: sorbitan fatty acid ester) is usually 10:1 to 1:10, preferably 8:1 to 1:8, and more preferably 4:1 to 1:4.

[0023] In this liquid pesticide composition, the mass ratio of aliphatic higher alcohol alkoxylate to sorbitan fatty acid ester (aliphatic higher alcohol alkoxylate: sorbitan fatty acid ester) is usually 10:1 to 1:10, preferably 5:1 to 1:5, and more preferably 3:1 to 1:3.

[0024] In this liquid pesticide composition, when the total content of this surfactant is 100 parts by mass, the content of dodecan-1-ol is usually 10 parts by mass or more and 80 parts by mass or less, preferably 15 parts by mass or more and 75 parts by mass or less, and more preferably 20 parts by mass or more and 70 parts by mass or less.

[0025] In this liquid pesticide composition, when the total content of this surfactant is 100 parts by mass, the content of aliphatic higher alcohol alkoxylate is usually 5 parts by mass or more and 70 parts by mass or less, preferably 8 parts by mass or more and 60 parts by mass or less, and more preferably 10 parts by mass or more and 50 parts by mass or less.

[0026] In this liquid pesticide composition, when the total content of the surfactant is 100 parts by mass, the content of sorbitan fatty acid ester is usually 5 parts by mass or more and 70 parts by mass or less, preferably 8 parts by mass or more and 60 parts by mass or less, and more preferably 10 parts by mass or more and 50 parts by mass or less.

[0027] In this liquid pesticide composition, the surfactants can all function as dispersion stabilizers for iminoctadine albesilate. According to the present invention, by combining the three components dodecane-1-ol, aliphatic higher alcohol alkoxylate, and sorbitan fatty acid ester, it is possible to suppress the generation of aggregates and suppress the increase in particle size during low-temperature storage, even though iminoctadine albesilate is included.

[0028] In this liquid pesticide composition, when the content of iminoctadine albesilate is 100 parts by mass, the total content of this surfactant is usually 5 parts by mass or more and 100 parts by mass or less, preferably 10 parts by mass or more and 90 parts by mass or less, and more preferably 20 parts by mass or more and 80 parts by mass or less.

[0029] This liquid pesticide composition typically contains water. Examples of water include deionized water, tap water, and groundwater. The water content in this liquid pesticide composition is typically 10 to 90 parts by mass, preferably 20 to 80 parts by mass, and more preferably 30 to 75 parts by mass per 100 parts by mass of the liquid pesticide composition.

[0030] This liquid pesticide composition may contain other components as needed. Examples of other components include other pesticide active ingredients other than iminoctadine albesilate, other surfactants other than this surfactant, and formulation aids.

[0031] This liquid pesticide composition may optionally contain one or more other pesticide active ingredients besides iminoctadine albesilate. Examples of other pesticide active ingredients include insecticidal ingredients, fungicidal ingredients, and herbicidal ingredients. It has been confirmed that the effects of the present invention can also be obtained when this liquid pesticide composition further contains other pesticide active ingredients besides iminoctadine albesilate.

[0032] In this liquid pesticide composition, the other pesticide active ingredients besides iminoctadine albesilate may be dispersed in water in a solid state or in the form of oil droplets.

[0033] This liquid pesticide composition may optionally contain one or more other surfactants besides the surfactant present. These other surfactants may be included as needed to disperse other pesticide active ingredients in water if the liquid pesticide composition further contains other pesticide active ingredients besides iminoctadine albesilate. Examples of other surfactants include nonionic surfactants, anionic surfactants, cationic surfactants, and amphoteric surfactants.

[0034] Examples of nonionic surfactants include, Polyoxyethylene polyoxypropylene (EO-PO) block copolymer; Polyoxyalkylene fatty acid esters such as polyoxyethylene fatty acid esters and polyoxyethylene polyoxypropylene fatty acid esters; Polyoxyalkylene polyaryl ethers such as polyoxyethylene tristyrylphenyl ether, polyoxyethylene polyaryl ether, and polyoxyethylene polyoxypropylene polyaryl ether; Polyoxyalkylene alkylaryl ethers such as polyoxyethylene alkylaryl ethers and polyoxyethylene polyoxypropylene alkylaryl ethers; polyoxyalkylene vegetable oils such as polyoxyethylene castor oil and polyoxyethylene polyoxypropylene castor oil; Polyoxyalkylene hydrogenated vegetable oils such as polyoxyethylene hydrogenated castor oil; Glycerin fatty acid ester These are some examples.

[0035] Examples of anionic surfactants include, Alkylaryl sulfonates such as dodecylbenzenesulfonate and alkylnaphthalenesulfonate; Dialkyl sulfosuccinates such as di(2-ethylhexyl) sulfosuccinate; Polyoxyalkylene polyaryl ether sulfates such as polyoxyethylene distyrylphenyl ether sulfates; Polyoxyalkylene polyaryl ether phosphate salts such as polyoxyethylene tristyrylphenyl ether phosphate salts These are some examples.

[0036] Examples of salts in the above-mentioned sulfonate salt, sulfate ester salt, and phosphate ester salt include sodium salt, potassium salt, calcium salt, and ammonium salt.

[0037] Examples of cationic surfactants include, Alkylamine hydrochlorides such as dodecylamine hydrochloride; Alkyl quaternary ammonium salts such as dodecyltrimethylammonium salt, alkyldimethylbenzylammonium salt, alkylpyridinium salt, alkylisoquinolinium salt, and dialkylmorpholinium salt; Benzethonium chloride; Polyalkylvinylpyridinium salt These are some examples.

[0038] Examples of amphoteric surfactants include N-laurylalanine, N,N,N-trimethylaminopropionic acid, N,N,N-trihydroxyethylaminopropionic acid, N-hexyl-N,N-dimethylaminoacetic acid, and 1-(2-carboxyethyl)pyrimidinium betaine. Furthermore, from the viewpoint of reducing viscosity at low temperatures, it is preferable that this liquid pesticide composition does not contain phospholipids, hydrogenated phospholipids, lecithin, soybean lecithin, and hydrogenated lecithin. Liquid pesticide compositions containing these components tend to have high viscosity at low temperatures (e.g., 10°C).

[0039] The content of surfactants other than the surfactant in this liquid pesticide composition is usually 1 part by mass or more and 30 parts by mass or less per 100 parts by mass of the liquid pesticide composition, preferably 2 parts by mass or more and 20 parts by mass or less, and more preferably 3 parts by mass or more and 15 parts by mass or less.

[0040] Examples of excipients for formulation include thickeners, preservatives, antifreezes, and defoamers.

[0041] Examples of thickening agents include polysaccharides such as xanthan gum, guar gum, gellan gum, dieutan gum, and cellulose nanofibers, as well as clay and silicates. This liquid pesticide composition may contain one or more thickening agents. The amount of thickening agent in this liquid pesticide composition is usually 0.01 parts by mass or more and 5 parts by mass or less per 100g by mass of the liquid pesticide composition, preferably 0.05 parts by mass or more and 3 parts by mass or less, and more preferably 0.1 parts by mass or more and 1 part by mass or less.

[0042] Examples of preservatives include p-hydroxybenzoic acid esters, salicylic acid derivatives, and isothiazolinone-based preservatives. This liquid pesticide composition may contain one or more preservatives. The amount of preservatives in this liquid pesticide composition is usually 0.01 parts by mass or more and 1 part by mass or less, preferably 0.05 parts by mass or more and 0.5 parts by mass or less, per 100 parts by mass of the liquid pesticide composition.

[0043] Examples of antifreeze agents include ethylene glycol, propylene glycol, urea, and glycerin. This liquid pesticide composition may contain one or more antifreeze agents. The amount of antifreeze agent in this liquid pesticide composition is usually 1 to 10 parts by mass, preferably 2 to 5 parts by mass, per 100 parts by mass of the liquid pesticide composition.

[0044] Examples of defoaming agents include silicone-based defoaming agents. This liquid pesticide composition may contain one or more defoaming agents. The amount of defoaming agent in this liquid pesticide composition is usually 0.01 parts by mass or more and 1 part by mass or less, preferably 0.05 parts by mass or more and 0.5 parts by mass or less, per 100 parts by mass of the liquid pesticide composition.

[0045] The particle size of this liquid pesticide composition refers to the particle size that accounts for 50% of the cumulative volume in the particle size distribution (volume median diameter). The particle size (volume median diameter) of this liquid pesticide composition can be measured using a laser diffraction / scattering particle size distribution analyzer (Horiba, Ltd., LA-950V2) by laser diffraction scattering (dispersion medium: ion-exchanged water, refractive index: [sample] 1.8–0.2i, refractive index: [dispersion medium] 1.333). In this liquid pesticide composition, the particle size (volume median diameter) of the pesticide active ingredient is usually 20 μm or less, and preferably 0.1 μm to 10 μm.

[0046] This liquid pesticide composition suppresses the increase in particle size of the pesticide active ingredient during low-temperature storage. Specifically, when this liquid pesticide composition is stored at -5°C for two weeks, the particle size change rate (%) represented by the following formula can be kept below 140%, preferably below 130%, more preferably below 125%, and even more preferably below 120%. Particle size change rate (%) = 100 × (Particle size after storage at -5°C for 2 weeks) / (Particle size immediately after manufacturing)

[0047] The viscosity of this liquid pesticide composition can be measured using a B-type viscometer. 200 mL of the liquid pesticide composition is placed in a 200 mL beaker and left to stand in a constant temperature water bath set to 5°C, 10°C, or 20°C. After confirming that the temperature of the liquid pesticide composition is within ±1°C of the measurement temperature, the viscosity is measured using a B-type viscometer (TVB-15M model, manufactured by Toki Sangyo, rotor No. 2, rotation speed: 6 rpm, measurement temperature: 5°C, 10°C, or 20°C). The viscosity of this liquid pesticide composition measured using a B-type viscometer (TVB-15M model, manufactured by Toki Sangyo, rotor No. 2, rotation speed: 6 rpm, measurement temperature: 5°C, 10°C, or 20°C) is usually 5000 mPa·s or less, preferably 4000 mPa·s or less, more preferably 3000 mPa·s or less, and even more preferably 2000 mPa·s or less. When the viscosity of the liquid pesticide composition is within the above range, it tends to have good storage stability at low temperatures. Specifically, it improves handling during use, and for example, it does not need to be returned to room temperature (e.g., 20°C) after storage at low temperatures and can be used as is. If the viscosity is 5000 mPa·s or higher, it is measured using rotor No. 3. Note that the liquid pesticide compositions described in Patent Documents 1 and 2 may lose their fluidity or thicken and become creamy when stored at low temperatures, and also tend to have high viscosity at low temperatures.

[0048] This liquid pesticide composition can be suitably used in agriculture as an aqueous suspension, aqueous emulsion, or suspension emulsion. Furthermore, this liquid pesticide composition can also be used in the preparation of other pesticide formulations, such as emulsions, oily suspensions, oily emulsions, microemulsions, and microcapsules.

[0049] This liquid pesticide composition contains iminoctadine albesilate as its active pesticide component, and by combining it with dodecane-1-ol, aliphatic higher alcohol alkoxylate, and sorbitan fatty acid ester, the formation of aggregates can be suppressed, and the increase in particle size during low-temperature storage can also be suppressed. Specifically, this liquid pesticide composition tends to be less prone to forming aggregates immediately after manufacturing and during low-temperature storage, and the increase in particle size during low-temperature storage is suppressed.

[0050] This liquid pesticide composition can be produced by mixing iminoctadine albesilate, dodecane-1-ol, aliphatic higher alcohol alkoxylate, and sorbitan fatty acid ester, and optionally other components. The method for producing this liquid pesticide composition includes the step of mixing iminoctadine albesilate, dodecane-1-ol, aliphatic higher alcohol alkoxylate, and sorbitan fatty acid ester to obtain an emulsion. The method for producing this liquid pesticide composition may further include the step of mixing the emulsion with water and optionally a formulation aid to obtain an aqueous emulsion. The method for producing this liquid pesticide composition may further include the step of mixing the aqueous emulsion with other pesticide formulations to obtain a suspoemulsion.

[0051] This liquid pesticide composition can be diluted with water as needed and applied to paddy fields, cultivated fields, orchards, lawns, non-agricultural land, etc. It can also be sprayed onto plants growing in paddy fields, etc., or onto the soil of paddy fields, etc. Application methods include, for example, surface spraying and foliar spraying. This liquid pesticide composition or its diluted solution can also be used for seed treatment, seedling tray treatment, etc. [Examples]

[0052] The present invention will be described in more detail below with reference to manufacturing examples and comparative manufacturing examples, but the present invention is not limited to these examples.

[0053] <Manufacturing Example 1> (Process 1) 13.70 parts by mass of iminoctadine albesilate stock solution, 2.00 parts by mass of antifreeze (product name: monoethylene glycol), 2.00 parts by mass of dodecane-1-ol (product name: Calcol 2098), 0.50 parts by mass of oleyl alcohol ethoxylate (product name: New Calgen D-1518), and 0.50 parts by mass of sorbitan fatty acid ester (product name: New Calgen D-931) were mixed and stirred to obtain 18.70 parts by mass of the oil phase. (Process 2) 42.58 parts by mass of deionized water and 0.14 parts by mass of an antifoaming agent (product name: KS-538) were mixed, and while stirring with a homogenizer, 18.70 parts by mass of the oil phase obtained in step 1 was added to obtain an emulsified liquid of 61.42 parts by mass.

[0054] (Step 3) 5.66 parts by mass of deionized water, 2.86 parts by mass of anionic surfactant (product name: SOPROPHOR FLK), 0.06 parts by mass of antifoaming agent (product name: KS-538), and 10.00 parts by mass of pyridaclomethyl were mixed and stirred, and wet-milled using a bead mill to obtain 18.58 parts by mass of suspension. SOPROPHOR FLK was used to disperse pyridaclomethyl, a bactericidal active ingredient, because it is a surfactant generally suitable for dispersing solid substances at room temperature. Furthermore, experiments have confirmed that the above suspension has good storage stability at low temperatures (in particular, there is no problem of particle size increase during low-temperature storage).

[0055] (Step 4) A thickening agent (product name: Veegum R 0.24 parts by mass and product name: Kelzan SPlus 0.12 parts by mass), a preservative (product name: Proxel GXL(S)) 0.20 parts by mass, and ion-exchanged water 19.44 parts by mass were mixed to obtain 20.00 parts by mass of a thickening agent-containing solution.

[0056] (Step 5) A liquid pesticide composition was obtained by mixing 61.42 parts by mass of the emulsified liquid prepared in step 2, 18.58 parts by mass of the suspension prepared in step 3, and 20.00 parts by mass of the thickener-containing liquid prepared in step 4.

[0057] The composition of the liquid pesticide composition is shown in Tables 1 to 3. In Tables 1 to 3, "Balance" represents the amount of water added to bring the total volume of the liquid pesticide composition to 100 parts by mass, i.e., the amount of water remaining from the other components when the total volume of the liquid pesticide composition is 100 parts by mass.

[0058] <Manufacturing Example 2> A liquid pesticide composition was obtained in the same manner as in Production Example 1, except that the amounts of the ingredients were as shown in Table 1.

[0059] <Manufacturing Example 3> (Process 1) 13.70 parts by mass of iminoctadine albesilate stock solution, 1.20 parts by mass of dodecane-1-ol (product name: Calcol 2098), 0.50 parts by mass of oleyl alcohol ethoxylate (product name: New Calgen D-1518), and 1.50 parts by mass of sorbitan fatty acid ester (product name: New Calgen D-931) were mixed and stirred to obtain 16.90 parts by mass of the oil phase. (Process 2) 44.38 parts by mass of deionized water and 0.14 parts by mass of an antifoaming agent (product name: KS-538) were mixed, and while stirring with a homogenizer, 16.90 parts by mass of the oil phase obtained in step 1 was added to obtain an emulsified liquid of 61.42 parts by mass.

[0060] (Step 3) 5.66 parts by mass of deionized water, 2.86 parts by mass of anionic surfactant (product name: SOPROPHOR FLK), 0.06 parts by mass of antifoaming agent (product name: KS-538), and 10.00 parts by mass of pyridaclomethyl were mixed and stirred, and wet-milled using a bead mill to obtain 18.58 parts by mass of suspension.

[0061] (Step 4) A thickening agent (product name: Veegum R 0.24 parts by mass and product name: Kelzan SPlus 0.12 parts by mass), a preservative (product name: Proxel GXL(S)) 0.20 parts by mass, and ion-exchanged water 19.44 parts by mass were mixed to obtain 20.00 parts by mass of a thickening agent-containing solution.

[0062] (Step 5) A liquid pesticide composition was obtained by mixing 61.42 parts by mass of the emulsified liquid prepared in step 2, 18.58 parts by mass of the suspension prepared in step 3, and 20.00 parts by mass of the thickener-containing liquid prepared in step 4.

[0063] <Manufacturing Example 4> A liquid pesticide composition was obtained in the same manner as in Production Example 3, except that the amounts of the ingredients were as shown in Table 1.

[0064] <Manufacturing Example 5> A liquid pesticide composition was obtained in the same manner as in Production Example 1, except that the amounts of the ingredients were as shown in Table 1.

[0065] <Manufacturing Example 6> A liquid pesticide composition was obtained in the same manner as in Production Example 1, except that in Step 2, 3.00 parts by mass of anionic surfactant (product name: SOPROPHOR FLK) was added to deionized water, and the amount of deionized water was adjusted so that the emulsion amounted to 61.42 parts by mass, and the amounts of the components were as shown in Table 1.

[0066] <Manufacturing Example 7> A liquid pesticide composition was obtained in the same manner as in Production Example 1, except that in steps 2 and 3, an antifoaming agent (product name: XIEAMETER ACP-1500) was used instead of the antifoaming agent (product name: KS-538), 3.00 parts by mass of anionic surfactant (product name: SOPROPHOR FLK) was added to deionized water in step 2, the amount of deionized water was adjusted so that the emulsion amounted to 61.42 parts by mass, and the amounts of the components were as shown in Table 1.

[0067] <Manufacturing Example 8> A liquid pesticide composition was obtained in the same manner as in Production Example 1, except that the amounts of the ingredients were as shown in Table 1.

[0068] <Manufacturing Examples 9-14> A liquid pesticide composition was obtained in the same manner as in Production Example 3, except that the amounts of the ingredients were as shown in Table 1.

[0069] <Comparative Manufacturing Example 1> A liquid pesticide composition was obtained in the same manner as in Production Example 7, except that the amounts of the ingredients were as shown in Table 1.

[0070] <Comparative Manufacturing Examples 2-4> A liquid pesticide composition was obtained in the same manner as in Production Example 1, except that the amounts of the ingredients were as shown in Table 1.

[0071] <Comparative Manufacturing Examples 5-7> A liquid pesticide composition was obtained in the same manner as in Production Example 3, except that the types and amounts of the ingredients were as shown in Table 1. Polyoxyethylene castor oil ether (trade name: New Calgen D-230) and EO-PO block polymer (trade name: Stepflow 26F) were used in Step 1.

[0072] <Comparative Manufacturing Example 8> (Process 1) 13.70 parts by mass of iminoctadine albesilate stock solution, 3.70 parts by mass of dodecane-1-ol (product name: Calcol 2098), 1.00 part by mass of hydrogenated lecithin (product name: SLP-White H), and 2.00 parts by mass of hexaglycerin stearate (product name: MS-5S) were mixed and stirred to obtain 20.40 parts by mass of the oil phase. (Process 2) 40.88 parts by mass of deionized water and 0.14 parts by mass of an antifoaming agent (product name: KS-538) were mixed and stirred using a homogenizer, and then 20.40 parts by mass of the oil phase obtained in step 1 were added to obtain an emulsified liquid of 61.42 parts by mass.

[0073] (Step 3) 5.66 parts by mass of deionized water, 2.86 parts by mass of anionic surfactant (product name: SOPROPHOR FLK), 0.06 parts by mass of antifoaming agent (product name: KS-538), and 10.00 parts by mass of pyridaclomethyl were mixed and stirred, and wet-milled using a bead mill to obtain 18.58 parts by mass of suspension.

[0074] (Step 4) A thickening agent (product name: Veegum R 0.24 parts by mass and product name: Kelzan SPlus 0.12 parts by mass), a preservative (product name: Proxel GXL(S)) 0.20 parts by mass, and ion-exchanged water 19.44 parts by mass were mixed to obtain 20.00 parts by mass of a thickening agent-containing solution.

[0075] (Step 5) A liquid pesticide composition was obtained by mixing 61.42 parts by mass of the emulsified liquid prepared in step 2, 18.58 parts by mass of the suspension prepared in step 3, and 20.00 parts by mass of the thickener-containing liquid prepared in step 4.

[0076] [Manufacturability of emulsifiers] The emulsified solution immediately after preparation in Step 2 was visually inspected, and its manufacturability was evaluated according to the following evaluation criteria. The results are shown in Tables 1 and 2. A "×" indicates that the manufacturability of the emulsified solution was judged to be extremely poor. ○: Uniform or fluid ×: Not uniform or not fluid

[0077] [Formation of aggregates] The liquid pesticide composition immediately after manufacturing in step 5 was visually inspected to determine the presence or absence of clumpy aggregates. If aggregates were detected, the liquid pesticide composition was mixed by inverting the container. If the aggregates could not be dispersed by mixing, it was determined that aggregates had formed. Furthermore, the liquid pesticide composition, which had been stored at -5°C for two weeks, was checked for the formation of aggregates using the same method after returning to room temperature. The results are shown in Tables 1 and 2. ○: No aggregate formation ×: Aggregates are present.

[0078] [Particle size change rate] For the liquid pesticide composition immediately after manufacturing in Step 5 and the liquid pesticide composition after storage at -5°C for two weeks, the median volume diameter was measured by laser diffraction scattering. For the liquid pesticide composition after storage at -5°C for two weeks, the measurement was taken after the liquid pesticide composition was returned to room temperature. When the measurement result for the liquid pesticide composition immediately after manufacturing in Step 5 is denoted as A, and the measurement result for the same liquid pesticide composition after storage at -5°C for two weeks is denoted as B, the particle size change rate X was calculated using the following formula. When the particle size change rate is less than 140%, it was judged that the increase in particle size during low-temperature storage was suppressed, and this was marked as ○. The results are shown in Tables 1 and 2. In Table 2, "Unmeasurable" indicates that aggregates occurred immediately after manufacturing or after storage at -5°C for two weeks, and the particle size could not be measured because the liquid pesticide composition was non-uniform. X(%) = 100 × B / A

[0079] [viscosity] 200 mL of the liquid pesticide composition of Production Example 7 was placed in a 200 mL beaker and left to stand in a constant temperature water bath set to 5°C. After confirming that the temperature of the liquid pesticide composition of Production Example 7 was 5 ± 1°C, the viscosity was measured using a Type B viscometer (TVB-15M model, manufactured by Toki Sangyo, rotor No. 2, rotation speed: 6 rpm, measurement temperature: 5°C). The viscosity at 10°C and 20°C was measured in the same manner. The viscosity of the liquid pesticide composition of Comparative Production Example 8 at 5°C, 10°C, and 20°C was also measured in the same manner. However, if the viscosity was 5000 mPa·s or higher, rotor No. 3 was used for measurement.

[0080] [Table 1]

[0081] [Table 2]

[0082] [Table 3]

[0083] The product names listed in the examples are explained below. Iminoctadine albesilate stock solution: A mixture of 73% by weight of iminoctadine albesilate, 12.0% by weight of ethylene glycol, 13.0% by weight of water, and 2% by weight of methanol, manufactured by Nippon Soda Co., Ltd. SOPROPHOR FLK: Polyoxyethylene tristyrylphenyl ether potassium phosphate salt, manufactured by Solvay Nikka; Monoethylene glycol: Ethylene glycol, manufactured by Mitsui Chemicals; Dodecane-1-ol: Calcol 2098, manufactured by Kao Corporation; Aliphatic higher alcohol alkoxylate: New Calgen D-1518, manufactured by Takemoto Oil Co., Ltd. Sorbitan fatty acid ester: New Calgen D-931, manufactured by Takemoto Oil Co., Ltd. KS-538: Silicone-based mixture, manufactured by Shin-Etsu Chemical Co., Ltd. Veegum R: Smectite Clay, manufactured by RTVanderbilt Company, Inc. Kelzan S Plus: Xanthan gum, manufactured by CP Kelco; Proxel GXL(S): 1,2-Benzisothiazolin-3-one, manufactured by Arcsada Japan; XIEAMETER ACP-1500: Dimethylsiloxane-treated silica, manufactured by Dow Chemical, Japan. Polyoxyethylene castor oil ether: New Calgen D-230, manufactured by Takemoto Oil Co., Ltd. EO-PO block polymer: Stepflow 26F, manufactured by STEPAN; SLP-White H: Hydrogenated lecithin (iodine value 10 or less), manufactured by Tsuji Oil Co., Ltd. MS-5S: Hexaglycerin stearate, manufactured by Sakamoto Pharmaceutical Co., Ltd.

Claims

1. Iminoctadine albesilate, Dodecane-1-ol, Aliphatic higher alcohol alkoxylates, and Contains sorbitan fatty acid ester, Liquid pesticide composition.

2. The dodecane-1-ol content is 0.75% by mass or more and 6% by mass or less. The liquid pesticide composition according to claim 1.

3. The mass ratio of iminoctadine albesylate to dodecane-1-ol is between 100:10 and 100:

50. The liquid pesticide composition according to claim 1 or 2.

4. The mass ratio of aliphatic higher alcohol alkoxylate to sorbitan fatty acid ester is 3:1 to 1:

3. The liquid pesticide composition according to claim 1 or 2.

5. The viscosity at 10°C is 4000 mPa·s or less. The liquid pesticide composition according to claim 1 or 2.

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