Antioxidant composition

Ergosterol analogs, such as dehydroergosterol, provide antioxidant and reducing properties by stabilizing free radicals, addressing the lack of known antioxidant activity in this class of compounds.

JP2026061886APending Publication Date: 2026-04-09KIRIN HOLDINGS KK
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Patent Information

Authority / Receiving Office
JP · JP
Patent Type
Applications
Current Assignee / Owner
Filing Date
2024-09-30
Publication Date
2026-04-09

AI Technical Summary

Technical Problem

Existing literature does not disclose the antioxidant activity of ergosterol analogs.

Method used

The discovery of ergosterol analogs, particularly dehydroergosterol compounds, which exhibit antioxidant activity by supplying electrons to free radicals and stabilizing them, thereby preventing cellular damage.

Benefits of technology

Ergosterol analogs effectively suppress free radical activity and oxidation of coexisting substances, demonstrating antioxidant and reducing capabilities comparable to α-tocopherol.

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Abstract

Providing antioxidant compositions. [Solution] The present invention provides an antioxidant composition comprising an ergosterol analog or a koji mold fermentation product containing an ergosterol analog. The ergosterol analog is preferably a compound in an oxidized form of ergosterol. The ergosterol analog is preferably at least one selected from the group consisting of dehydroergosterol, 14-dehydroergosterol, 14,15-dehydroergosterol, and 24(28)-dehydroergosterol.
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Citation Information

Patent Citations

  • Method for producing 14-dehydroergosterol by microbial fermentation

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  • Anti-inflammatory agent

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  • Method for producing aspergillus fermentation extract which high-contains 14-dehydroergosterol

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  • Novel compound having immunosuppressive action

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  • Production method of 14-dehydroergosterol

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