Drug transfer adapter

Abstract

To provide a drug transfer adapter that prevents exposure to drugs. [Solution] A drug transfer adapter comprising: a body having a first end and a second end opposite to the first end; a transfer spike extending from the first end of the body and penetrating the closure of the container to define an opening; a connector extending from the second end of the body; and a fixing member extending from the body and having a first side and a second side opposite to the first side, the first side having an adhesive surface for fixing the body to the container, wherein when the transfer spike penetrates the closure of the container and is fully inserted into the container and the first end of the body contacts the container, the fixing member is movable between a first non-fixed position perpendicular to the longitudinal axis of the transfer spike and a second fixed position parallel to the longitudinal axis of the transfer spike and wrapped around the container or a part of the container with the adhesive surface engaging with the container, in order to avoid interference by the fixing member when the transfer spike penetrates the closure.

Description

Technical Field

[0001] The present disclosure generally relates to a drug delivery adapter, and more specifically, to a drug delivery adapter having a fixing member.

[0002] This application claims priority to U.S. Application No. 17 / 002,299, filed Aug. 25, 2020, entitled "Drug Delivery Adapter", the entire disclosure of which is hereby incorporated herein by reference in its entirety.

Background Art

[0003] Healthcare providers who reconstitute, transport, and administer hazardous drugs such as cancer treatments can expose themselves to the risk of exposure to these drugs and pose a danger to the healthcare environment. Unintentional exposure to chemotherapy can affect the nervous system, damage the reproductive system, and increase the risk of developing blood cancer in the future. Some drugs must be dissolved or diluted before they are administered, which involves transferring a solvent from a syringe through a needle into a sealed vial containing the drug in powder or liquid form. The drug can be inadvertently released into the atmosphere in gaseous form or aerosolized during withdrawal of the needle from the vial and while the needle is inside the vial if there is a pressure difference between the inside of the vial and the surrounding atmosphere. To reduce the risk of healthcare providers being exposed to toxic drugs, the transfer of these drugs is accomplished using a closed-system transfer device or system. The closed-system transfer device or system can include a syringe adapter, a patient connector, an IV bag spike, and a vial adapter.

Summary of the Invention

[0004] In one aspect or embodiment, the drug transfer adapter includes a body having a first end and a second end located opposite the first end, and a transfer spike extending from the body and defining an opening, the transfer spike being configured to penetrate the closure of a container and including a connector extending from the body and a fixing member extending from the body. The fixing member has a first side and a second side located opposite the first side, the first side of the fixing member including an adhesive surface configured to fix the body to the container.

[0005] The fixing member may include an extension portion extending from the main body, a tapered portion extending from the extension portion, and a rectangular portion extending from the tapered portion. The rectangular portion may be wider than the extension portion. The fixing member may be flexible. The transport spike may extend from a first end of the main body. The connector extends from a second end of the main body. The main body may be rectangular and include a first grip surface and a second grip surface located opposite the first grip surface. The first and second grip surfaces may each be arched. The main body may be disc-shaped.

[0006] The main body may be cylindrical, having a side wall extending between a first end and a second end of the main body. The connector may extend from the main body at a position midway between the first and second ends of the main body. The main body may include a first grip surface and a second grip surface located opposite the first grip surface, and the first and second grip surfaces are each arched. The fixing member may include an extension portion extending from the main body, a tapered portion extending from the extension portion, and a rectangular portion extending from the tapered portion, the extension portion of the fixing member extending along the side wall of the main body. The adhesive surface of the extension portion of the fixing member is in contact with the side wall of the main body to fix the fixing member to the main body.

[0007] The fixing members may include a first fixing member and a second fixing member positioned on the opposite side of the first fixing member. The first and second fixing members may be integrally formed. The first and second fixing members may define an opening for receiving a connector, having a portion of the adhesive surface on the first side of the first and second fixing members that contacts the body, in order to fix the first and second fixing members to the body.

[0008] The fixing member may have a length of at least 50% of the length of the transport spike. The fixing member may have a length of at least 90% of the length of the transport spike. [Brief explanation of the drawing]

[0009] The aforementioned and other features and advantages of this disclosure, as well as the methods for achieving them, will become more apparent and the disclosure itself will be better understood by referring to the following description of embodiments of this disclosure taken in conjunction with the accompanying drawings. [Figure 1] Figure 1 is a front view of a drug transfer adapter according to one aspect or embodiment of the present application. [Figure 2] Figure 2 is a perspective view of the drug transfer adapter shown in Figure 1, showing the first position of the fixing member. [Figure 3] Figure 3 is a perspective view of the drug transfer adapter shown in Figure 1, showing the second position of the fixing member. [Figure 4] Figure 4 is a front view of a drug transfer adapter according to a second aspect or one embodiment of the present application. [Figure 5] Figure 5 is a perspective view of the drug transfer adapter shown in Figure 4, showing the first position of the fixing member. [Figure 6] Figure 6 is a perspective view of the drug transfer adapter shown in Figure 4, showing the second position of the fixing member. [Figure 7] Figure 7 is a front view of a drug transfer adapter according to a third aspect or one embodiment of the present application. [Figure 8] Figure 8 is a perspective view of the drug transfer adapter shown in Figure 7, showing the first position of the fixing member. [Figure 9] Figure 9 is a perspective view of the drug transfer adapter shown in Figure 7, which is used in conjunction with the infusion container. [Figure 10] Figure 10 is a partial perspective view of the drug transfer adapter shown in Figure 7, illustrating the drug transfer adapter used with the infusion container. [Figure 11] Figure 11 is a partial perspective view of the drug transfer adapter shown in Figure 7, illustrating the drug transfer adapter used with the drug vial. [Figure 12] Figure 12 is a side view of a drug transfer adapter according to a fourth aspect or embodiment of this application. [Figure 13] Figure 13 is a front view of the drug transfer adapter shown in Figure 12. [Figure 14] Figure 14 is a partial perspective view of the drug transfer adapter shown in Figure 12, illustrating the drug transfer adapter used with the drug vial. [Figure 15] Figure 15 is a perspective view of a drug transfer adapter according to a fifth aspect or embodiment of this application. [Figure 16] Figure 16 is a rear view of the drug transfer adapter shown in Figure 15. [Figure 17] Figure 17 is a perspective view of a drug transfer adapter according to a sixth aspect or embodiment of this application. [Figure 18] Figure 18 is a partial perspective view of the drug transfer adapter shown in Figure 17, illustrating the drug transfer adapter used with the drug vial. [Figure 19] Figure 19 is a partial perspective view of the drug transfer adapter shown in Figure 17, illustrating the drug transfer adapter used in conjunction with the infusion container.

[0010] Corresponding reference numerals indicate corresponding parts in some of the figures. The examples presented herein illustrate exemplary embodiments of the disclosure and should not be construed as limiting the scope of the disclosure in any way. [Modes for carrying out the invention]

[0011] The following description is provided to enable those skilled in the art to create and use the described embodiments intended for carrying out the invention. However, various modifications, equivalents, variations, and substitutes will be readily apparent to those skilled in the art. Any and all such modifications, variations, equivalents, and substitutes are intended to fall within the spirit and scope of the invention.

[0012] Hereinafter, for explanatory purposes, “top,” “bottom,” “right,” “left,” “vertical,” “horizontal,” “top,” “bottom,” “horizontal,” “vertical,” and their derivatives shall be used in relation to the present invention as oriented in the drawings. However, it will be understood that the present invention may presuppose various alternative modifications unless explicitly specified otherwise. It should also be understood that the specific devices shown in the accompanying drawings and described below are merely exemplary embodiments of the present invention. Therefore, specific dimensions and other physical features relating to the aspects disclosed herein should not be considered limiting.

[0013] Referring to FIGS. 1-3, a drug delivery adapter 10 according to one aspect or one embodiment includes a body 12, a delivery spike 14 extending from the body 12, a connector 16 extending from the body 12, and a fixing member 18 extending from the body 12. The body 12 has a first end 20 and a second end 22 disposed on the opposite side of the first end 20. The delivery spike 14 defines an opening 24, and the delivery spike 14 is configured to penetrate the closure of the container. The connector 16 is configured to connect to a syringe barrel or a syringe adapter. The fixing member 18 has a first side 26 and a second side 28 disposed on the opposite side of the first side 26. The first side 26 of the fixing member 18 includes an adhesive surface configured to fix the body 12 to the container. The opening 24 of the delivery spike 14 is in fluid communication with the connector 16 to enable fluid transfer through the delivery spike 14, through the connector 16, and to a component connected to the connector 16. The drug delivery adapter 10 is configured to transfer a drug or fluid from one container, such as a syringe, to another container, such as an IV bag, an IV bottle, a vial, etc. In one aspect or one embodiment, the drug delivery adapter 10 is an IV bag adapter and is configured to be connected to a syringe adapter and a spike port of the IV bag.

[0014] Referring again to Figures 1-3, the fixing member 18 comprises an extension portion 30 extending from the main body 12, a tapered portion 32 extending from the extension portion 30, and a rectangular portion 34 extending from the tapered portion 32. The rectangular portion 34 is wider than the extension portion 30, which increases the surface area of ​​the fixing member 18, thereby increasing the contact area of ​​the first side surface 26 of the fixing member 18. The rectangular portion 34 is rectangular in shape, but other suitable shapes and configurations can be utilized. The fixing member 18 is flexible and is configured to wrap around a container or part of a container, such as the spike port of an IV bag, to fix the drug transfer adapter 10 to the container. The fixing member 18 has a first position shown in Figure 2 that allows the fixing member 18 to be fixed to the container, and a second position shown in Figure 3 that allows the transfer spike 14 to penetrate the container without interference from the fixing member 18. The fixing member 18 may be movable by 90 degrees when moving from a first position to a second position and vice versa, but other suitable angles may be utilized. In one aspect or embodiment, the fixing member 18 is formed from an adhesive tape such as adhesive foil, but other suitable arrangements may be utilized. In one aspect or embodiment, the fixing member 18 includes a liner that has been peeled off before use. In one aspect or embodiment, the fixing member is formed from a medical-grade laminate foil having adhesive on a single side covered with a removable liner, for example, 3M® 9792R aluminum foil tap available from 3M Company, but other suitable tapes may be utilized. In one aspect or embodiment, the fixing member 18 is configured to permanently or semi-permanently fix the drug transfer adapter 10 to the container so that the drug transfer adapter 10 cannot be easily removed from the container.

[0015] The transfer spike 14 extends from the first end 20 of the body 12, and the connector 16 extends from the second end 22 of the body 12, although other suitable configurations may be utilized. In one aspect or embodiment, the transfer spike 14 may be disposed at a right angle to the connector 16. The body 12 is rectangular, although other suitable shapes and configurations may be utilized. The body 12 includes a first grip surface 36 and a second grip surface 38 disposed on the opposite side of the first grip surface 36. During use of the drug delivery adapter 10, a healthcare provider can grip the first and second grip surfaces 36, 38 and penetrate the container with the transfer spike 14. The first and second grip surfaces 36, 38 are arcuate, although other suitable shapes and configurations may be utilized.

[0016] Referring again to FIGS. 1 - 3, the drug delivery adapter 10 includes two fixing members 18, with the first fixing member 40 disposed on the opposite side of the second fixing member 42. The first fixing member 40 and the second fixing member 42 are integrally formed, although other suitable configurations can be utilized. The first fixing member 40 and the second fixing member 42 define an opening 44 for receiving the connector 16. A portion of the adhesive surface on the first side 26 of the first and second fixing members 40, 42 is in contact with the body 12 to fix the first and second fixing members 40, 42 to the body.

[0017] In one aspect or embodiment, the fixing member 18 has a length of at least 50% of the length of the transfer spike 14. In a further aspect or embodiment, the fixing member 18 has a length of at least 90% of the length of the transfer spike 14. The fixing member has a sufficient length and surface area to have a sufficient adhesive area to increase the force required to remove the drug delivery adapter 10 from the container, while not being so long as to cause non - adhering portions or defects of the fixing member 18 that could compromise the strength of the interface between the fixing member 18 and the container.

[0018] Referring to Figures 4-6, a drug transfer adapter 50 according to a second aspect or embodiment is shown. The drug transfer adapter 50 is similar to the drug transfer adapter 10 shown in Figures 1-3, except that the main body 12 is disc-shaped, the extension portions 30 of each fixing member 18 are shorter, and the rectangular portions 34 are wider.

[0019] Referring to Figures 7-11, a drug transfer adapter 80 according to a third aspect or embodiment is shown. The drug transfer adapter 80 is similar to the drug transfer adapter 10 of Figures 1-3, with the differences discussed below. The drug transfer adapter 80 includes only a single fixing member 18. The body 12 may be cylindrical, having a side wall 82 extending between a first end 20 and a second end 22 of the body 12. The connector 16 extends from the body 12 at a position midway between the first and second ends 20, 22 of the body 12. The body 12 may include a first grip surface 84 and a second grip surface 86 located opposite the first grip surface 84, and the first and second grip surfaces 84, 86 are each arched. The extension 30 of the fixing member 18 extends along the side wall 82 of the body 12. The adhesive surface of the extension portion 30 of the fixing member 18 is in contact with the side wall 82 of the main body 12 in order to fix the fixing member 18 to the main body 12.

[0020] Referring to Figures 9-11, the drug transfer adapter 80 is shown fixed to the spike port 90 of the IV bag 92 (Figures 9 and 10) and to the drug vial or container 96 (Figure 11). As shown in Figures 9 and 10, the transfer spike 14 penetrates the closure of the spike port 90 with at least a portion of the transfer spike 14 received within the spike port 90. After the transfer spike 14 is inserted into the spike port 90, the fixing member 18, in particular the rectangular portion 34 of the fixing member 18, is wrapped around the spike port 90 of the IV bag 92, and the drug transfer adapter 80 is fixed to the IV bag 92 by engaging the adhesive surface on the first side surface 26 of the fixing member 18 with the spike port 90. The syringe adapter 94 is fixed to the connector 16 so that the IV bag 92 is in fluid communication with the syringe adapter 94 via the transfer spike 14, the body 12, and the connector 16. The side wall 82 of the main body 12 surrounds a portion of the syringe adapter 94 when the syringe adapter 94 is secured to the connector 16. A syringe barrel (not shown) may be secured to the syringe adapter 94. The syringe adapter 94 may operate in the same manner as the syringe adapter described in U.S. Patent Application Publication No. 2015 / 0297454, which is entirely incorporated herein by reference. As shown in Figure 11, the drug transfer adapter 80 is connected to the drug vial 96 in a similar manner to how it connects to the IV bag 92. The transfer spike 14 penetrates the closure of the drug vial 96 so that the transfer spike 14 is in fluid communication with the drug vial 96, and the rectangular portion 34 of the fixing member 18 is pressed against a portion of the drug vial 96 such as the cap 98, securing the drug transfer adapter 80 to the drug vial 96 via engagement between the adhesive surface on the first side surface 26 of the fixing member 18 and the drug vial 96.

[0021] Referring to Figures 12-14, a drug transfer adapter 100 according to a fourth aspect or embodiment is shown. The drug transfer adapter 100 is similar to the drug transfer adapter 80 in Figures 7-11, except for the differences which are discussed below. The fixing member 18 of the drug transfer adapter 100 includes only the extension portion 30; that is, the single fixing member 18 is rectangular. As shown in Figure 14, the drug transfer adapter 100 is connected to the drug vial 96 in a similar manner to the drug transfer adapter 80 discussed above and shown in Figure 11. The transfer spike 14 penetrates the closure of the drug vial 96 so that the transfer spike 14 is in fluid communication with the drug vial 96, and the extension portion 30 of the fixing member 18 is pressed against a part of the drug vial 96, thereby fixing the drug transfer adapter 100 to the drug vial 96 through engagement between the adhesive surface of the fixing member 18 and the drug vial 96.

[0022] Referring to Figures 15 and 16, a drug transfer adapter 110 according to a fifth aspect or embodiment is shown. The drug transfer adapter 110 is similar to the drug transfer adapter 100 of Figures 12-14, with the differences discussed below. The fixing member 18 further includes a mounting portion 112 extending perpendicularly from the extension portion 30 of the fixing member 18. The mounting portion 112 provides an additional surface area to further secure the attachment of the fixing member 18 to the body 12 of the drug transfer adapter 110. The mounting portion 112 is rectangular, but other suitable shapes and configurations can be utilized.

[0023] Referring to Figures 17-19, a drug transfer adapter 120 according to a sixth aspect or embodiment is shown. The drug transfer adapter 120 is similar to the drug transfer adapter 100 of Figures 12-14, with the differences discussed below. Rather than providing a single fixing member 18, the drug transfer adapter 120 includes two fixing members 122, 124 in a similar manner to the drug transfer adapter 10 shown in Figures 1-3. The first fixing member 122 and the second fixing member 124 define an opening 126 that receives a connector 16. As shown in Figure 18, the drug transfer adapter 120 is connected to the drug vial 96 in a similar manner to the drug transfer adapter 80 discussed above and shown in Figure 11. The transfer spike 14 penetrates the closure of the drug vial 96 so that the transfer spike 14 is in fluid communication with the drug vial 96, and the extension portion 30 of the fixing member 18 is pressed against a portion of the drug vial 96, thereby fixing the drug transfer adapter 120 to the drug vial 96 through the engagement between the adhesive surface of the fixing member 18 and the drug vial 96. As shown in Figure 19, when fixing the drug transfer adapter 120 to the IV bag 92, the transfer spike 14 penetrates the closure of the spike port 90 with at least a portion of the transfer spike 14 received within the spike port 90. After the transfer spike 14 is inserted into the spike port 90, the extension portions 30 of the fixing members 122, 124 are pressed onto the spike port 90 of the IV bag 92, and the drug transfer adapter 120 is fixed to the IV bag 92 through the engagement between the adhesive surfaces on the fixing members 122, 124 and the spike port 90. The extensions 30 of the fixing members 122 and 124 are aligned with the longitudinal axis of the transport spike 14.

[0024] While this disclosure has been described to have an exemplary structure, it is subject to further modification within its spirit and scope. Therefore, this application is intended to encompass any variation, use, or adaptation of this disclosure using its general principles. Furthermore, this application is intended to cover any deviations from this disclosure that fall within the scope of the appended claims, within the scope of known or customary practices in the relevant art. Wherever possible, one or more features of any aspect or embodiment described above can be combined with one or more features of any other aspect or embodiment.

Claims

1. A drug transport adapter, A body having a first end and a second end positioned on the opposite side of the first end, A transfer spike extending from the first end of the main body and defining an opening, the transfer spike configured to penetrate the closing portion of the container, A connector extending from the second end of the main body, A fixing member extending from the main body, having a first side surface and a second side surface located opposite to the first side surface, wherein the first side surface of the fixing member has an adhesive surface configured to fix the main body to the container, Equipped with, When the transfer spike penetrates the closing portion of the container and the transfer spike is fully inserted into the container and the first end of the main body is at least partially in contact with the container, the fixing member is In order to avoid interference by the fixing member when the transfer spike penetrates the closing portion, the fixing member is positioned at a first non-fixed position substantially perpendicular to the longitudinal axis of the transfer spike, A drug transfer adapter wherein the fixing member is positioned substantially parallel to the longitudinal axis of the transfer spike, is at least partially wrapped around the container or a portion of the container, and is movable between a second fixing position in which the adhesive surface engages with the container and a second fixing position.

2. The drug transfer adapter according to claim 1, wherein the fixing member comprises an extension portion extending from the main body, a tapered portion extending from the extension portion, and a rectangular portion extending from the tapered portion.

3. The drug transfer adapter according to claim 2, wherein the rectangular portion is wider than the extended portion.

4. The drug transfer adapter according to claim 1, wherein the fixing member is flexible.

5. The drug transfer adapter according to claim 1, wherein the transfer spike extends from the first end of the main body.

6. The drug transfer adapter according to claim 5, wherein the connector extends from the second end of the main body.

7. The drug transfer adapter according to claim 1, wherein the main body is rectangular and includes a first grip surface and a second grip surface located on the opposite side of the first grip surface.

8. The drug transfer adapter according to claim 7, wherein the first and second grip surfaces are each arched.

9. The drug transfer adapter according to claim 1, wherein the main body is disc-shaped.

10. The drug transfer adapter according to claim 1, wherein the main body is cylindrical in shape and has a side wall extending between the first end and the second end of the main body.

11. The drug transfer adapter according to claim 10, wherein the connector extends from the main body at a position midway between the first and second ends of the main body.

12. The drug transfer adapter according to claim 10, wherein the main body includes a first grip surface and a second grip surface located on the opposite side of the first grip surface, and the first and second grip surfaces are each curved.

13. The drug transfer adapter according to claim 10, wherein the fixing member comprises an extension portion extending from the main body, a tapered portion extending from the extension portion, and a rectangular portion extending from the tapered portion.

14. The drug transfer adapter according to claim 10, wherein the extended portion of the fixing member extends along the side wall of the main body.

15. The drug transfer adapter according to claim 14, wherein the adhesive surface of the extension portion of the fixing member is in contact with the side wall of the main body in order to fix the fixing member to the main body.

16. The drug transfer adapter according to claim 1, wherein the fixing member comprises a first fixing member and a second fixing member disposed on the opposite side of the first fixing member.

17. The drug transfer adapter according to claim 16, wherein the first fixing member and the second fixing member are integrally formed.

18. The drug transfer adapter according to claim 17, wherein the first fixing member and the second fixing member define an opening for receiving the connector and have a portion of the adhesive surface on the first side of the first fixing member and the second fixing member that contacts the main body in order to fix the first fixing member and the second fixing member to the main body.

19. The drug transfer adapter according to claim 1, wherein the length of the fixing member is at least 50% of the length of the transfer spike.

20. The drug transfer adapter according to claim 1, wherein the length of the fixing member is at least 90% of the length of the transfer spike.

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