Method for producing fish bone meal for bone health and the manufacturing equipment thereof

The method for producing fish bone meal, through a mineral powder mix of fish bones, vitamin D3, and vinegar fermentation, addresses calcium absorption issues by achieving a balanced calcium-to-phosphorus ratio and enhancing bone health markers.

JP2026067794APending Publication Date: 2026-04-21NAT PINGTUNG UNIV OF SCI & TECH
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Patent Information

Authority / Receiving Office
JP · JP
Patent Type
Applications
Current Assignee / Owner
NAT PINGTUNG UNIV OF SCI & TECH
Filing Date
2025-04-15
Publication Date
2026-04-21

AI Technical Summary

Technical Problem

Existing methods for bone health care, such as calcium intake, do not reliably ensure calcium absorption due to imbalanced calcium-to-phosphorus ratios in the blood, leading to potential calcium loss from bones.

Method used

A method involving the preparation of a mineral powder from fish bones containing calcium and phosphorus, mixed with vitamin D3, heated in stages, and fermented with vinegar to convert vitamin D3 to calcitriol and break down nutrients into smaller, easily absorbable molecules.

Benefits of technology

The method enhances calcium absorption by achieving a favorable calcium-to-phosphorus ratio, increasing osteocalcin levels, and improving bone health indicators like alkaline phosphatase and total cholesterol levels, without adverse effects.

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Abstract

This invention provides a method for producing fish bone meal for bone health. [Solution] The method includes a preparation step of preparing a mineral powder made from fish bones and containing calcium and phosphorus, and a base powder containing vitamin D3; a mixing step of mixing the mineral powder and the base powder to obtain a mixed powder; a heating step including a first step of heating the mixed powder in an environment of 40°C to 60°C and a second step of heating the mixed powder in an environment of 60°C to 80°C; and an addition step of adding vinegar to the mixed powder to cause a fermentation reaction in at least a part of the mixed powder.
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Description

Technical Field

[0001] The present invention relates to a method for manufacturing a health food and its manufacturing equipment, and particularly to a method for manufacturing fish bone powder for bone health care and its manufacturing equipment.

Background Art

[0002] Regarding bone health care, the intake of calcium is mainly emphasized. For example, Patent Document 1 discloses a health food for calcium intake.

[0003] However, whether calcium is reliably absorbed by the human body even when calcium is ingested from food or health food is a key point for achieving effects such as strengthening bone mass and improving physical condition.

[0004] It has been reported that when the ratio of calcium to phosphorus in the blood is 235000:135000, the calcium in the blood can be reliably absorbed by the bone to achieve the purpose of strengthening bone mass.

[0005] If the ratio of calcium to phosphorus in the blood is not this value, on the contrary, calcium in the bone will flow out.

[0006] Therefore, regarding bone health care, in addition to ingesting vitamin D to improve calcium absorption, considering the ratio between calcium and phosphorus so that the ingested calcium can reliably achieve the bone health care effect is an issue in this technical field.

Prior Art Documents

Patent Documents

[0007]

Patent Document 1

Summary of the Invention

Problems to be Solved by the Invention

[0008] In view of the above, the object of the present invention is to provide a method for producing fish bone meal for bone health that allows ingested calcium to be more easily absorbed into the bones and reliably achieves the health benefits of improving bone quality, as well as the production equipment for the same. [Means for solving the problem]

[0009] The present invention comprises a preparation step of preparing a mineral powder made from fish bones and containing calcium and phosphorus, and a base powder containing vitamin D3, A mixing step of mixing the mineral powder and the base powder to obtain a mixed powder, A heating step comprising a first step of heating the mixed powder in an environment of 40°C to 60°C, and a second step of heating the mixed powder in an environment of 60°C to 80°C, The present invention provides a method for producing fish bone meal for bone health, characterized by comprising an addition step of adding vinegar to the mixed powder so that at least a portion of the mixed powder undergoes a fermentation reaction.

[0010] The present invention relates to a manufacturing apparatus for producing fish bone meal for bone health, A raw material feeding unit comprising: a first feeding module for storing and dispensing mineral powder containing calcium and phosphorus; and a second feeding module separate from the first feeding module for storing and dispensing base powder containing vitamin D3; A processing unit comprising a heating furnace installed downstream of the raw material supply unit and communicating with the first supply module and the second supply module, and a stirring mechanism installed inside the heating furnace, The present invention provides a manufacturing apparatus for producing fish bone meal for bone health, characterized by comprising an additive unit connected to the processing unit and also connected to the heating furnace, and including a material addition module for adding vinegar. [Effects of the Invention]

[0011] In the manufacturing method and equipment of the present invention, since fish bones contain tricalcium phosphate, after mixing the mediating powder and the base powder and heating, vitamin D3 is first subjected to a hydroxylation reaction to convert it into calcitriol, which has biological activity and promotes calcium absorption. Furthermore, a fermentation reaction with vinegar converts vitamin D3 and other nutrients that promote calcium absorption into smaller molecules that are more easily absorbed. Compared to using raw materials that do not contain phosphorus, the phosphorus content is increased, making it easier for users to achieve a calcium-to-phosphorus ratio of 2:1 in their blood after ingesting the fish bone meal for bone health according to the present invention. Experiments have demonstrated an increase in the amount of osteocalcin, an indicator of bone formation in the blood, and therefore, calcium absorption can be improved from multiple angles, and the bone health effect can be reliably achieved. [Brief explanation of the drawing]

[0012] [Figure 1] This is a flowchart illustrating an example of the method for producing fish bone meal for bone health maintenance according to the present invention. [Figure 2] This figure shows an example of the manufacturing equipment for fish bone meal for bone health according to the present invention. [Figure 3] This figure shows the difference between a control group fed with general feed and an experimental group fed with fish bone meal produced using the methods and equipment examples of the present invention. [Figure 4] This figure shows the differences in alkaline phosphatase (ALKP) and total cholesterol (TCHO) between the control group and the experimental group described above. The symbol "*" indicates that p < 0.05 compared to the control group. [Figure 5]This figure compares the differences in weight change and food intake after 12 weeks among four groups: a normal group (Ovarian removal and general feed), a control group (OV) (Ovarian removal and no calcium), an experimental group (FBC) (Ovarian removal and the above-mentioned fish bone meal), a first comparison group (SC) (Ovarian removal and seaweed calcium), a second comparison group (Carbonate) (Ovarian removal and calcium carbonate), and a third comparison group (Citrate) (Ovarian removal and calcium citrate). The symbol "*" indicates that p < 0.05 compared to the control group. [Figure 6] Figure 5 shows the data for alkaline phosphatase and total cholesterol measured at 12 weeks in the group divisions shown. The symbol "*" indicates that p<0.05 compared to the experimental group, and the symbol "**" indicates that p<0.01 compared to the experimental group. [Figure 7] Figure 5 shows the data obtained by measuring serum phosphorus, serum calcium, and osteocalcin at 12 weeks in the group divisions shown. The symbol "*" indicates that p<0.05 compared to the experimental group, the symbol "**" indicates that p<0.01 compared to the experimental group, and the symbol "***" indicates that p<0.001 compared to the experimental group. [Figure 8] This figure is similar to Figure 6, but shows the data measured after 16 weeks, and the symbol "*" indicates that p < 0.05 compared to the control group. [Figure 9] This figure is similar to Figure 7, but shows the data measured after 16 weeks, and the symbol "*" indicates that p<0.05 compared to the control group. [Figure 10] Similar to Figure 9, this figure shows the triglyceride data for each group, and the symbol "*" indicates that p < 0.05 compared to the experimental group. [Modes for carrying out the invention]

[0013] An example of the method for producing fish bone meal for bone health of the present invention, as shown in Figure 1, includes a pretreatment step 10, a preparation step 11, a mixing step 12, a heating step 13, and an addition step 14.

[0014] Examples of the manufacturing method of the present invention are carried out by examples of manufacturing equipment for manufacturing fish bone powder for bone health care of the present invention as shown in FIG. 2. Examples of the manufacturing equipment of the present invention include an autoclave 2, a raw material feeding unit 3 installed downstream of the autoclave 2, a processing unit 4 installed downstream of the raw material feeding unit 3, and an addition unit 5 connected to the processing unit 4.

[0015] As shown in FIGS. 1 and 2, in the pretreatment step 10, using the autoclave 2, different fish bones are treated with high-temperature steam at 80°C to 140°C for 50 minutes to 80 minutes at a pressure higher than the normal atmospheric pressure to form water-soluble mineral powder.

[0016] In this embodiment, different fish bones are treated with high-temperature steam at 130°C for 60 minutes at a pressure higher than the normal atmospheric pressure to form water-soluble mineral powder.

[0017] In addition to being rich in calcium, the fish bones contain tricalcium phosphate and collagen. Note that for fish bones, regardless of whether they are from aquaculture or wild sources, sufficient heavy metal detection is performed to ensure that they meet the relevant detection standards.

[0018] When treating a plurality of fish bones with high-temperature steam at a pressure higher than the normal atmospheric pressure, in addition to softening the bone structure by the interaction of pressure and temperature for a considerable period, the nutritional components of the bone are not lost, and it can be further pulverized into mineral powder.

[0019] [[ID=z2]] In addition, bacteria that may remain in the fish bones are killed by the treatment with high-temperature steam, thus maintaining the necessary food hygiene safety.

[0020] In the preparation step 11, mineral powder with a water content of less than 3% and containing calcium and phosphorus, base powder containing vitamin D3, and fish scale powder containing gelatin are prepared.

[0021] The raw material supply unit 3 includes a first supply module 31 for storing and supplying the mineral powder, a second supply module 32 separate from the first supply module 31 for storing and supplying the base powder, and a third supply module 33 that is in communication with the processing unit 4 for storing and supplying the fish scale powder.

[0022] The processing unit 4 includes a heating furnace 41 that is in communication with a first feeding module 31, a second feeding module 32, and a third feeding module 33, and a stirring mechanism 42 installed inside the heating furnace 41.

[0023] After the mineral powder, base powder, and fish scale powder are fed into the heating furnace 41 by the raw material feeding unit 3, the stirring mechanism 42 is activated to perform the mixing step 12, thereby mixing the mineral powder, base powder, and fish scale powder to obtain a mixed powder.

[0024] Furthermore, in the heating step 13, the heating furnace 41 can be set to a heating mode with multiple different temperature ranges, and the step includes a first stage of heating the mixed powder in an environment of 40°C to 60°C and a second stage of heating the mixed powder in an environment of 60°C to 80°C.

[0025] By heating in two stages, it is possible to avoid excessive heating that would destroy the structure of the nutrients in the mixed powder, depending on the characteristics of the calcium, phosphorus, vitamin D3, and other nutrients contained in the powder. Furthermore, for vitamin D3, a reaction is triggered that converts it to calcitriol, which is naturally produced in the human body, thereby achieving the effect of activating the component.

[0026] The additive unit 5 is in communication with the heating furnace 41 and includes a material addition module 51 for adding vinegar. Examples of vinegar include edible vinegar.

[0027] In heating step 13, an addition step 14 is performed to further convert the vitamin D3 and other nutrients in the mixed powder into smaller molecules that are more easily absorbed. In addition step 14, vinegar is added to the mixed powder by the material addition module 51, causing a fermentation reaction to break down the activated vitamin D3 and other nutrients into smaller molecules that are more easily absorbed by the human body. The fermentation reaction takes place for 1 to 2 hours.

[0028] The amount of vinegar solution added to the mixed powder is 1 wt% based on the total weight of the processed powder.

[0029] After vinegar is added and the reaction is complete, the mixed powder can be used to produce various fish bone meal foods by subsequently granulating it into capsules or tablets.

[0030] Examples General experimental materials 1. Laboratory mice The female mice used in the following experiments, BALB / C mice (8 weeks old, weighing 20g or more), were purchased from BioLASCO Taiwan Co., Ltd.

[0031] All experimental mice were housed in animal rooms equipped with independent air conditioning systems under laboratory conditions consisting of alternating 12-hour light and 12-hour dark periods, a temperature maintained at 24°C ± 2°C, and a relative humidity maintained at 60% to 70%. The experimental animals were given free access to water and food.

[0032] All experimental procedures involving laboratory animals complied with the legal provisions of Taiwan's Animal Protection Act and were carried out in accordance with the guidelines of the Animal Experimentation Committee of the Taiwan Council of Agriculture.

[0033] General Procedure 1. Statistical analysis All experiments described below were repeated three times. Experimental data for all test groups are expressed as mean ± standard deviation (SD) and analyzed using an analysis of variance (ANOVA) test with GraphPad Prism software to assess differences between groups. Statistical significance is indicated by p<0.05.

[0034] As shown in Figure 3, in order to demonstrate the effects of ingesting fish bone meal food, an experiment was conducted using a control group fed with general feed and an experimental group fed with fish bone meal food produced using the method and equipment of the present invention.

[0035] Example 1: Evaluation of the effects of the fish bone meal of the present invention on the absorption of calcium, phosphorus, and other biochemical markers in normal mice. To evaluate the effectiveness of the fish bone meal of the present invention on the absorption of calcium, phosphorus, and other biochemical markers (such as alkaline phosphatase and total cholesterol) in normal mice, the following experiment was conducted. Female mice described in Section 1 of "General Experimental Materials" were randomly divided into a control group and an experimental group (n=8 in each group). Before the start of feeding, a single blood sample was taken from the cheek pouch vein of each mouse as a baseline.

[0036] The control group of mice was orally administered a standard diet (purchased from Altromin Spezialfutter GmbH & Co.kg), while the experimental group of mice was orally administered the fish bone meal food containing the fish bone meal of the present invention. Each mouse was fed once a day for a total of 112 days (i.e., 16 weeks).

[0037] After completing 112 days of administration of either a general feed or a fish bone powder food containing the fish bone powder of the present invention, blood samples were collected from the cheek pouch veins of mice in each group by puncture and left at room temperature for 2 hours to coagulate.

[0038] Subsequently, the mixture was centrifuged at 3000 rpm and 4°C for 10 minutes, and the resulting supernatant was collected.

[0039] Subsequently, the collected supernatants were diluted with redistilled water to obtain serum samples.

[0040] Subsequently, serum samples were analyzed for calcium, phosphorus, alkaline phosphatase, and total cholesterol concentrations using a Catalyst One Veterinary Blood Chemistry Analyzer (manufactured by IDEXX Laboratories, Inc.).

[0041] As shown in Figure 3, which illustrates the results after a certain period of time, the calcium and phosphorus content in the serum of the experimental group were higher than those in the control group.

[0042] Referring to Figure 4, alkaline phosphatase (ALKP, ALP), an indicator of bone formation, is generally found to be higher in growing children and pregnant women. In normal adults, the level is typically between 20 IU / L and 140 IU / L, and excessively high levels may indicate bone cancer, multiple myeloma, or fractures.

[0043] Comparing the alkaline phosphatase data of the control group and the experimental group, the experimental group's data generally met the normal criteria and tended to be superior to that of the control group. This demonstrates that consuming the fish bone meal food according to the present invention does not cause abnormalities in alkaline phosphatase levels in the body.

[0044] Furthermore, in the fish bone meal food according to the present invention, vitamin D3 is pre-converted to calcitriol. Therefore, in order to ensure that consuming this fish bone meal food does not cause excessive cholesterol in the serum, total cholesterol (TCHO) levels were compared between the control group and the experimental group.

[0045] As shown in Figure 4, both groups had cholesterol levels within the normal range of 200 mH / dl or less. Furthermore, the values ​​in the experimental group that consumed the fish bone meal food were relatively low and showed a superior trend compared to the control group. Therefore, it has been proven that consuming the fish bone meal food according to the present invention does not adversely affect total cholesterol.

[0046] Furthermore, in order to compare the differences between the fish bone meal food according to the present invention and other calcium supplement foods, mice were used as experimental subjects, and the differences in data were compared between a normal group (Normal) in which the ovaries were removed and fed a normal diet, a control group (OV) in which the ovaries were removed and no calcium was given, an experimental group (FBC) in which the ovaries were removed and fed the fish bone meal food according to the present invention, a first comparison group (SC) in which the ovaries were removed and seaweed calcium was given, a second comparison group (Carbonate) in which the ovaries were removed and calcium carbonate was given, and a third comparison group (Citrate) in which the ovaries were removed and calcium citrate was given.

[0047] Example 2: Evaluation of the effects of the fish bone meal food of the present invention on body weight, food intake, and absorption of calcium, phosphorus, and other biochemical markers in ovariectomized mice. The following experiments were conducted to evaluate the effectiveness of the fish bone meal food of the present invention on the absorption of calcium, phosphorus, and other biochemical markers such as alkaline phosphatase, total cholesterol, osteocalcin, and triglycerides in ovariectomized mice, and to compare the effectiveness of the fish bone meal food with other types of calcium supplements.

[0048] A. Effects of fish bone meal diet over 12 weeks in ovariectomized mice. The ovaries of female mice, as described in Section 1 of "General Experimental Materials," were removed by ovariectomy when the mice reached 8 weeks of age. The resulting ovariectomized mice were randomly divided into six groups: a normal group, a control group, an experimental group, and three comparison groups (n=8 in each group).

[0049] Before administering each group of mice the diets shown in Table 1, weight gain and food intake were measured, and a single blood sample was taken from the cheek pouch vein of each mouse as a baseline. Each mouse was fed orally once daily for a total of 12 weeks.

[0050] [Table 1]

[0051] After completing 12 weeks of administration of each diet, the weight gain rate of mice in each group was measured to eliminate any differences between administration of the standard diet and administration of the standard diet supplemented with a different type of calcium.

[0052] Since changes in body weight are related to calcium absorption and food intake, we also examined the differences in food intake between the groups.

[0053] Subsequently, blood samples were collected by puncturing the veins in the cheek pouches of the mice in each group.

[0054] Subsequently, the blood sample was centrifuged at 3000 rpm at 4°C for 10 minutes, and the resulting supernatant was collected.

[0055] Subsequently, the collected supernatants were diluted with redistilled water to obtain serum samples.

[0056] Subsequently, the concentrations of calcium, phosphorus, alkaline phosphatase, and total cholesterol were measured using a Catalyst One Veterinary Blood Chemistry Analyzer (manufactured by IDEXX Laboratories, Inc.), and the concentrations of osteocalcin and triglycerides in the serum samples were measured using an enzyme-linked immunosorbent assay (ELISA) kit.

[0057] The obtained data was analyzed according to the procedure described in Section 1 of "General Procedures".

[0058] B. Effects of fish bone meal over 16 weeks in ovariectomized mice The administration of each diet to mice, as described in Section A of this example, was extended until the end of week 16.

[0059] Subsequently, for each group of mice, excluding the normal group, the concentrations of calcium, phosphorus, osteocalcin, alkaline phosphatase, total cholesterol, and triglycerides in serum samples were measured as described in Section A of this example.

[0060] The obtained data was analyzed according to the procedure described in Section 1 of "General Procedures".

[0061] Figure 5 compares the differences in weight changes and food intake among the groups.

[0062] To eliminate the influence of general feed and calcium supplements, we first compared the percentage of weight gain. As shown in Figure 5, the percentage of weight gain was similar for the normal group, experimental group, and the first to third comparison groups, with the exception of the control group that did not receive calcium.

[0063] Furthermore, since changes in body weight are related to calcium absorption and food intake, we also compare them with food intake.

[0064] According to the data shown in Figure 5, there were no significant differences in food intake among the groups, and therefore, the conditions set for each group should not affect the changes in calcium absorption in each group.

[0065] The data shown in Figures 5 to 7 represent the results of an experiment conducted over 12 weeks.

[0066] Figure 6 shows the data obtained after 12 weeks of measurement of alkaline phosphatase and total cholesterol for the group divisions shown in Figure 5.

[0067] As shown in Figure 6, alkaline phosphatase is closely related to bone formation, and total cholesterol is also involved in calcium absorption; therefore, measurements were performed for both alkaline phosphatase and total cholesterol.

[0068] According to the data shown in Figure 6, regarding alkaline phosphatase, except for the third comparison group given calcium citrate, whose values ​​were relatively low, the experimental group's values ​​were close to those of the first and second comparison groups, considering that the control group showed elevated values ​​relative to the normal group.

[0069] Furthermore, while total cholesterol is involved in calcium absorption, the data showed that the experimental group had significantly lower total cholesterol levels compared to the other groups.

[0070] Therefore, the experimental group showed no adverse effects in alkaline phosphatase data and performed better than the other groups in total cholesterol data.

[0071] Figure 7 shows the data obtained from measuring serum phosphorus, serum calcium, and osteocalcin after 12 weeks, based on the groupings shown in Figure 5.

[0072] As shown in Figure 7, serum phosphorus and calcium levels were significantly lower in the control group of mice that were not given calcium, according to the serum phosphorus and calcium data.

[0073] The serum phosphorus and calcium levels in the experimental group were clearly higher than those in the control group.

[0074] Furthermore, osteocalcin is the second most abundant compound in bone after collagen, and is mainly secreted by osteoblasts. Therefore, it is expected that measuring osteocalcin levels will reveal whether bone is actually growing.

[0075] As a result, according to the data shown in Figure 7, the experimental group's data was higher than the control group's data, as expected, and better than the performance of the first to third comparison groups who consumed other calcium supplements.

[0076] Figure 8 is similar to Figure 6, but it shows the data measured after each group of mice was given their respective diet for 16 weeks.

[0077] Figure 9 is similar to Figure 7, but it shows the data measured after each group of mice was given their respective diet for 16 weeks.

[0078] Referring to Figures 8 and 9, which combine Figures 6 and 7, data from experiments conducted for the control group, experimental group, and the first to third comparison groups for an extended period of 16 weeks showed that the experimental group was able to maintain its alkaline phosphatase expression even after the extended experimental period.

[0079] Despite showing an increase in total cholesterol levels at the end of week 16 compared to the values ​​measured at the end of week 12, the experimental group remained lower than the other groups.

[0080] Regarding the main indicators of serum phosphorus, serum calcium, and osteocalcin, the expression of serum phosphorus and serum calcium remained superior to the data from the first to third comparison groups even after the extension of the experimental period. In particular, the osteocalcin data was significantly superior to the data from the first to third comparison groups. Therefore, even when the period is extended to 16 weeks, it can be proven that the fish bone meal food according to the present invention has superior expression compared to seaweed calcium, calcium carbonate, and calcium citrate.

[0081] Figure 10 is similar to Figure 6, but shows serum triglyceride data measured after each group of mice was fed their respective diet for 16 weeks.

[0082] Furthermore, according to the data in Figure 10, the experimental group showed a superior effect in reducing triglycerides.

[0083] According to the above, the present invention provides a method for producing fish bone meal for bone health and the production equipment thereof. By combining the effects of vitamin D3 and vinegar with fish bone containing tricalcium phosphate and collagen, components that aid in calcium absorption are formed, and the molecules are pre-processed to make them easier to absorb. Furthermore, experiments have demonstrated that after ingestion of the produced fish bone meal, osteocalcin levels in the blood increased, demonstrating that it has the effect of aiding in bone growth and formation and strengthening bone quality.

[0084] Therefore, the objectives of the present invention can be reliably achieved.

[0085] The above embodiments are illustrative in illustrating the principles and effects of the present invention and do not limit it. A person skilled in the art can make some modifications and alterations to the above embodiments, provided that they do not deviate from the spirit and scope of the invention. Therefore, all modifications and alterations made by a person skilled in the art, provided that they do not deviate from the spirit of the invention, should also be considered to fall within the scope of protection of the present invention. [Industrial applicability]

[0086] The method for producing fish bone meal for bone health and the production equipment for the same that of the present invention are suitable for producing fish bone meal for bone health. [Explanation of symbols]

[0087] 10 Pre-treatment steps 11 Preparation Steps 12 Mixing Steps 13. Heating step 14 Addition Step 2. Pressure cooker 3. Raw material feeding unit 31 First feeding module 32 Second feeding module 33 Third feeding module 4 Processing Units 41 Heating furnace 42 Stirring mechanism 5 Addition Unit 51 Material Addition Module

Claims

1. A preparation step involves preparing a mineral powder made from fish bones and containing calcium and phosphorus, and a base powder containing vitamin D3. A mixing step of mixing the mineral powder and the base powder to obtain a mixed powder, A heating step comprising a first step of heating the mixed powder in an environment of 40°C to 60°C, and a second step of heating the mixed powder in an environment of 60°C to 80°C, A method for producing fish bone meal for bone health, comprising an addition step of adding vinegar to the mixed powder to cause a fermentation reaction in at least a portion of the mixed powder.

2. The method for producing fish bone powder for bone health according to claim 1, further comprising a pretreatment step of heating the fish bones with high-temperature steam before the preparation step to form the fish bones as water-soluble mineral powder.

3. A method for producing fish bone meal for bone health according to claim 1 or 2, characterized in that, in the preparation step, fish scale meal containing gelatin is further prepared, and in the mixing step, the fish scale meal, the mineral powder and the base powder are mixed to obtain the mixed powder.

4. The method for producing fish bone meal for bone health according to claim 3, characterized in that the mineral powder is bone meal with a water content of less than 3%.

5. A manufacturing facility for producing fish bone meal for bone health, A raw material feeding unit comprising: a first feeding module for storing and dispensing mineral powder containing calcium and phosphorus; and a second feeding module separate from the first feeding module for storing and dispensing base powder containing vitamin D3; A processing unit comprising a heating furnace installed downstream of the raw material supply unit and communicating with the first supply module and the second supply module, and a stirring mechanism installed inside the heating furnace, A manufacturing apparatus for producing fish bone meal for bone health, characterized by comprising an additive unit connected to the processing unit and also connected to the heating furnace, and including a material addition module for adding vinegar.

6. The manufacturing equipment for producing fish bone meal for bone health according to claim 5, further comprising a pressure vessel installed upstream of the raw material supply unit and for processing multiple fish bones with high-temperature steam to form mineral powder.

7. The manufacturing equipment for producing fish bone meal for bone health according to claim 5 or 6, characterized in that the raw material supply unit is in communication with the heating furnace and further includes a third supply module for storing and supplying fish scale meal containing gelatin.

8. The manufacturing equipment for producing fish bone meal for bone health according to claim 5 or 6, characterized in that the heating furnace of the processing unit can be set to a plurality of different temperature range heating modes.

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