IKAROS Zinc Finger Family Degrading Agent and its Use

JP2026095542APending Publication Date: 2026-06-11GILEAD SCIENCES INC

Patent Information

Authority / Receiving Office
JP · JP
Patent Type
Applications
Current Assignee / Owner
GILEAD SCIENCES INC
Filing Date
2026-03-30
Publication Date
2026-06-11

Smart Images

  • Figure 2026095542000001
    Figure 2026095542000001
  • Figure 2026095542000002
    Figure 2026095542000002
  • Figure 2026095542000003
    Figure 2026095542000003
Patent Text Reader

Abstract

To provide a method for treating a disease. [Solution] This disclosure generally relates to compounds that bind to IKAROS family zinc finger (IKZF) proteins such as IKZF2 (Helios) and / or IKZF4 (Eos) and act as degrading agents thereof. This disclosure further relates to the use of compounds for the preparation of pharmaceuticals for the treatment of diseases and / or conditions, including cancer, through the binding and degradation of IKZF proteins such as IKZF2 and / or IKZF4. Surprisingly, remarkable effects are achieved according to the present invention, as described in detail and specifically demonstrated herein, and these remarkable effects could not be readily predicted by those skilled in the art from the prior art.
Need to check novelty before this filing date? Find Prior Art

Claims

[Claim 1] The invention described in the specification.