Accessories for injection devices, including a pivotable cover.

Abstract

To provide an accessory that enables easier operation of the needle safety device. [Solution] An accessory 200 for an injection device 100, wherein the injection device 100 has a safety shield 150, at least one flange 155 adapted to allow a user to grasp the injection device 100, and a syringe sheath 120 movable from a pre-injection position to a lockout position relative to at least one flange 155. The accessory 200 comprises a main body portion having a recess adapted to receive the safety shield 150 of the injection device 100 and a slot adapted to receive at least one flange 155 of the injection device 100.

Description

Technical Field

[0001] The present disclosure relates to accessories for an injection device.

Background Art

[0002] Needle safety devices are commonly used in combination with syringes when performing injections to reduce the risk of accidental needle sticks that can lead to transmission of blood - borne pathogens. These needle safety devices are usually required to protect healthcare providers (HCPs), such as nurses, who often use syringes to inject patients. These needle safety devices can generally be classified into one of two types: (1) passive devices that automatically cover the needle after injection without requiring additional steps from the user to move the device, and (2) devices that require additional steps by the user to move the needle safety function part. For various reasons, users may fail to perform the additional actions required to operate non - passive devices. Therefore, needle safety devices are generally considered to be superior in terms of their ability to protect users from accidental needle sticks. Healthcare institutions and healthcare systems often require the use of needle safety devices in situations where HCPs perform injections. Furthermore, needle safety devices are desirable for reducing the risk of injury, infection, and spread of blood - borne pathogens to patients, family members, caregivers, and any person who may come into contact with the injection device during the injection process and when disposing of the used syringe, whether the injection is performed by the user themselves or by a caregiver.

[0003]

[0004] ​​​​​​​​​​​A commonly used example of a needle safety device is by Becton Dickinson. It is a device manufactured under the UltraSafe® family. fe (trademark) consists of two plastic components and a specially designed plunger rod. It consists of a spring that is assembled into the syringe. Once the injection is complete, the plunger rod Engage with the latch on the UltraSafe® housing component, move the device, This extends one of the housing components on the needle and locks it in place, locking out Set to the T position. An example of the UltraSafe (trademark) device is shown in Figures 1A and 1B.

[0005] Figure 1A shows the device in its ready-to-use state, i.e., in the pre-injection position, before the injection is administered. Figure 1B shows the device in a safe, used state, i.e., the lockout position, after the injection is complete. The device is shown.

[0006] Figures 2A, 2B, 2C, and 2D show the use of an UltraSafe® device. Typical instructions are shown below. Use UltraSafe® as shown in these instructions. The process for doing so is essentially the same as that for administering an injection using an exposed syringe. Yes. Pinching the skin and injecting at a 45-degree angle is essential to limit the depth of the injection. Therefore, the injection is administered subcutaneously and not intramuscularly (too deep) or intradermally (into the skin). Ensure that the injection is delivered correctly. Injections that are too shallow or too deep can cause problems for drugs intended for subcutaneous injection. It may affect the pharmacokinetics (PK) and pharmacodynamics (PD).

[0007] As shown in Figures 2A to 2D, to achieve subcutaneous injection, the syringe must be used appropriately. The injection process is complex, and the procedure varies from user to user, which can lead to differences in injection depth and drug administration. This can affect the efficacy of the injection. Health care professionals such as nurses should be aware of the importance of using syringes in injection procedures. They are proficient and have received this training. However, techniques vary from nurse to nurse, and this is the case. It can affect PK and PD. Furthermore, typical injection techniques require the use of both hands. The nurse holds the syringe with one hand and administers the injection with the other, but this can cause problems for children who may move during the injection. It becomes difficult to administer injections to any difficult patient. Furthermore, nurses have difficulty using syringes. Even when there are no problems, patients are often afraid of syringes and needles, and injections can be a source of anxiety for patients. It often results in an unpleasant experience.

[0008] It is particularly difficult for patients and caregivers to use syringes such as UltraSafe™. It is difficult. This is because the usage process is not only complicated, but the syringe with the exposed needle is This is because it tends to cause anxiety in patients. [Overview of the project] [Problems that the invention aims to solve]

[0009] Therefore, it enables easier operation of needle safety devices, such as UltraSafe™. We need to develop accessories to enable this functionality. [Means for solving the problem]

[0010] In one aspect of the present invention, a safety shield is provided, and the user is able to grasp the injection device. At least one flange adapted to the above, and injection into at least one flange An attachment for an injection device having a syringe sheath that is movable from the forward position to the lockout position. an article is provided, the accessory comprising a recess adapted to receive a safety shield of an injection device, and a slot adapted to receive at least one flange of the injection device, a body portion, and a cover coupled to the body portion, the recess and the slot being exposed in an open position to receive the safety shield and the flange of the injection device respectively, and the cover being pivotable between the open position where the recess and the slot are exposed to receive the safety shield and the flange of the injection device respectively, and a closed position where the recess and the slot are at least partially closed to hold the injection device in the body portion, the slot being shaped such that at least one flange is resisted from moving distally and proximally relative to the body portion, and the syringe sheath is movable proximally relative to the body portion from a pre-injection position to a lock-out position. In this way, the cover can be opened such that the recess and the slot can be more easily accessed. Then, when the cover is closed, the slot holds the flange in a predetermined position, but the syringe sheath is movable and thus does not interfere with the function of the injection device.

[0011]

[0012] In another aspect of the invention, an accessory for an injection device having a needle cap is provided, the accessory comprising a body portion having a recess adapted to receive the injection device, and a cover coupled to the body portion, the cover being pivotable between an open position where the recess is exposed to receive the injection device and a closed position where the cover at least partially closes the recess to hold the injection device in the body portion, and a cap removal device comprising a gripping portion adapted to hold the needle cap, the cap removal device being movable relative to the body portion. The cover is moved by a user between the open position and the closed position. ​ The proximal end is adapted to move the cover from the open position to the closed position. When moved, the gripping part is moved toward the end of the accessory, and the needle cap is removed from the syringe. It comprises a distal end adapted to be removed at least partially.

[0013] In this way, the needle cap can be automatically removed when the cover is closed. This is a lever that moves the cap removal device and allows the needle cap to be removed. This is achieved by a cover that functions in a way that is easy for less dexterous users to use. This method provides a simple and reliable mechanism for removing the needle cover. The bar is designed to reduce the amount of force required by the user when removing the cap. It offers mechanical advantages for moving the object.

[0014] In another aspect of the present invention, an accessory for an injection device having a needle cap is provided, and this accessory It comprises a main body portion having a recess adapted for receiving an injection device, and connected to the main body portion The cover has an open position in which a recess is exposed to receive the injection device, and the cover is A closed position that holds the injection device to the main body by at least partially closing the recess, and a pivot between these two positions. A cap removal device comprising a movable cover and a gripping part, the cap removal The device has an extended configuration that allows the needle cap to pass between the gripping parts, and the gripping parts are the needle cap It has a shrinkage configuration that holds the needle cap and removes it at least partially from the injection device. The cover and cap removal device are equipped with a cap removal device, and the cover and cap removal device are equipped with a cap removal device, and the cover is open When moved from the position towards the closed position, the cap removal device changes from an extended configuration to a retracted configuration. They are connected to each other in a way that allows them to transition to the next state.

[0015] In this way, the injection device can be loaded into the accessory without the gripping part interfering with the needle cap. It is possible. Next, when the cover is closed, the gripping part automatically removes the needle cap. It closes on the needle cap. Also, after the cover is removed, the gripping part is opened again. Release the cover so that it can be separated from the accessories.

[0016] In another aspect of the present invention, an accessory for an injection device having a needle cap is provided, and this accessory It comprises a main body portion having a recess adapted for receiving an injection device, and connected to the main body portion The cover has an open position in which a recess is exposed to receive the injection device, and the cover is A closed position that holds the injection device to the main body by at least partially closing the recess, and a pivot between these two positions. A cap comprising a movable cover and a gripping portion adapted to hold the needle cap. The removal device is a cap removal device that moves from the initial position to the forward position of the main body In contrast, it is movable in the axial direction and removes the needle cap from the injection device, cap removal device The main body is equipped with a cap removal device that moves axially relative to the main body. It is equipped with tracks that are positioned so as to when the injection device is positioned in the main body. The cap removal device is adapted to be pressed against the truck by the injection device. Yes, they are.

[0017] In this way, the injection device has the function of holding the needle cap removal device inside the track. This will eliminate the need for additional components and simplify the design and manufacturing process.

[0018] The needle cap (often also called the "needle boot" or "needle shield") is rigid. It may be a needle cap or a non-rigid needle cap. A rigid needle cap has at least two components It may be formed of constituent elements, for example, a rigid outer shell and a syringe when in a given position It may include an inner body surrounding the upper needle. The inner body may be a flexible inner body, an elastic inner body , or it may be a flexible inner body. This inner body may be a rubber inner body. Alternatively, a non-rigid needle cap may be used, in which case the needle cap is a single flexible The body may be a rigid body, an elastic body, or a flexible body, for example, a rubberized needle boot. [Brief explanation of the drawing]

[0019] Embodiments of the present invention will be described simply by reference to the following drawings. [Figure 1A] This is a perspective view of an injection device in a ready-to-use state before use. [Figure 1B] A perspective view of an injection device in a secure lockout state. [Figure 2A] Figure 1 is an example of a side view showing a typical use of the injection device. [Figure 2B] Figure 1 is an example of a side view showing a typical use of the injection device. [Figure 2C] Figure 1 is an example of a side view showing a typical use of the injection device. [Figure 2D] Figure 1 is an example of a side view showing a typical use of the injection device. [Figure 3] This is a perspective view of the accessories for the injection device, which are in a closed configuration. [Figure 4] This is a perspective view of the accessories in the open configuration. [Figure 5] This is a perspective view of an open-configuration accessory that includes an injection device within the accessory. [Figure 6] This is a perspective view of a closed-configuration accessory that includes an injection device within the accessory. [Figure 7] This is an internal diagram of the injection device and accessories without a cover. [Figure 8] This is an enlarged perspective view of the accessory cap removal device and cover in the open position; the main body is not shown. [Figure 9] This is a further enlarged perspective view of the cap removal device and cover; the main body is not shown. [Figure 10] This is a further perspective view of the accessories in an open configuration, with the injection device located inside the accessories. [Figure 11] This is a perspective view of the cap removal device and cover in the closed position; the main body is not shown. [Figure 12] This is a perspective view of the base of the accessory. [Figure 13] This is an internal diagram of the main unit of the accessory. [Figure 14] This is a plan view of the accessory cap removal device. [Figure 15] This is a further perspective view of the main body. [Modes for carrying out the invention]

[0020] Figures 1A and 1B show a manual injection device 100 suitable for use with the accessories of this disclosure. The injection device 100 extends from the proximal end, which has a needle 130, to the distal end with an opening. It is equipped with a syringe 110. The distal end of the syringe opening is sealed by a stopper 140. Needle The cap 190 is positioned to cover the needle 130.

[0021] The syringe 110 is fixed inside the syringe sheath 120 by the syringe locking element 125. The syringe lock element 125 is provided with contact surfaces that are opposite each other in the diametrical direction. The flange of a standard syringe is restricted between these surfaces. By restricting movement, the syringe 110 does not move relative to the syringe sheath 120. I'll do that.

[0022] The syringe sheath 120 is the distal end of the opening, into which the syringe 110 is inserted. A distal opening end and a proximal opening end that allow the syringe 110 to be inside the sheath 120 When fixed in place, it has an opening proximal end from which the needle 130 extends. The 150 is movably mounted on the syringe sheath 120. Lud 150 is in a retracted position where needle 130 extends beyond the proximal end of the safety shield (Figure) (Figure 1A) and the extension position where the safety shield extends beyond the proximal end of the needle 130 (Figure It is movable between (as shown in Figure 1B) and . In the second position shown in Figure 1B, needle 13 The 0 is covered by a safety shield 150, thereby shielding the user from the needle. This prevents injuries caused by needle punctures in accidents.

[0023] The user grasps the injection device 100 equipped with a conventional dirt grip (shown in Figure 2). Therefore, the safety shield 150 has a flange 155 at its distal end or in that direction. It is equipped with. The flange 155 shown in Figure 1 extends from the safety shield 150. .

[0024] The safety shield 150 is supported by the biasing element 160, which supports the syringe sheath 120 (Figure 1B). The biasing element is biased at its extended position relative to the (indicated). The biasing element is shown in Figures 1A and 1B. 160 is a coil positioned between the syringe sheath 120 and the safety shield 150. Taking the form of a pull, the safety shield 150 is thus positioned relative to the syringe sheath 120. It is biased towards its proximal position and its extended location.

[0025] The releaseable locking mechanism 180 is securely positioned in its retracted position relative to the syringe sheath 120. The entire shield 150 is held. The locking mechanism 180 ensures that the safety shield 150 is syringe-safe. A locked position (Figure 1A) in which the locking mechanism 180 prevents movement relative to the 120, and The locking mechanism 180 prevents the safety shield 150 from moving relative to the limb sheath 120. It is movable between the unlocked position and the unlocked position. Once the locking mechanism is engaged, When moved to the release position, the safety shield 150 is under the influence of the coil spring 160. It moves towards that extended position (Figure 1B).

[0026] In the apparatus shown in Figures 1A and 1B, the safety shield 150 and syringe sheath 120 The locking mechanism 180 between the two is provided on the safety shield 150 and a pair of flexible racks It takes the form of a latch arm 181, which is on the opposing latch surface 183 on the syringe sheath 120. The flexible latch arms 181 engage with their individual latch surfaces 183. It is biased to the first position, and thus the safety mechanism is applied to the syringe sheath 120. Movement of the holder 150 to the proximal position is prevented. The flexible latch arm 181 resists this bias. When moved, the latch arm 181 disengages from its individual latch surfaces 183. This allows the safety shield 150 to move proximal to the syringe sheath 120. do.

[0027] The latch arm 181 is moved by the plunger rod 170 from the first position to the second position It is configured to move to the following. The plunger rod 170 is located at its proximal end. An elongated member configured to engage with the stopper 140, and which disperses the volume of the drug from the needle 130. To deliver the required amount, move the stopper 140 proximal to the longitudinal axis of the syringe body. It is equipped with a member. At its distal end, or in that direction, the plunger rod 170 has The working surface 175 is configured to deliver the injectable drug by moving the plunger rod 170 in the proximal direction. An operating surface 175 is provided on which the user can place their thumb or finger to drive the mechanism. The plunger rod 170 approaches the end of its movement within the syringe body, or here When they reach the working surface 175 of the plunger rod 170, they are connected to the syringe sheath 1 The flexible latching arm extends outward to a position where it is no longer engaged with the latch surface 183 on 20. The Mu 181 is deflected. In this way, the locking mechanism is released at the end of the injection, and the safety shield is released. 150 moves to its extended position.

[0028] Although not visible in the attached drawings, the manual injection device shown in Figures 1A and 1B is used after the injection is complete. The safety shield 150 may further be provided with a safety lock to lock it in its extended position. can.

[0029] Referring to Figure 3, the UltraSafe™ device and other injection devices 100 are used in the injection device 100. There is an accessory 200. In this specification, accessory 200 is a specific example of the injection device 100 and The description uses UltraSafe (trademark). However, accessory 200 is It can be used with injection devices other than UltraSafe® devices. For example, accessories can be used with other injection devices. It can be used with UltraSafe Plus® devices. The structure of accessory 200 is, It can be modified to match the form factor of any suitable injection device.

[0030] The accessory 200 comprises the main body 202 and the cover 204. The accessory 200 is an injection The distal end 206 is positioned towards or over the injection site when performing the procedure. It has a proximal end 208 opposite the distal end 206. The accessory 200 is a cover 20 4 has a window 210 inside. The main body 202 on the opposite side of the accessory 200 also has another window.

[0031] Referring to Figure 4, the cover 204 is connected to the main body portion 202. Specifically, The bar 204 is pivotally connected to the main body portion 202 around a pair of pivot parts 216. Each of the moving parts 216 is positioned facing each side of the accessory 200. Part 216 includes an opening 218 in the main body part 202, and the protruding part 203 inside the cover 204 It penetrates this. Alternatively, the protruding part 203 is located in the main body part 202, and the opening 218 is It may be provided within the bar 204. The protrusion 203 is shown in detail in Figures 8 and 9. Part 203 is rotatable within the opening 218, thereby allowing the cover 204 to rotate within the main body. It can rotate relative to 202. In this way, the cover 204 is open to the position shown in Figure 4. It is movable between the open position and the closed position shown in Figure 3.

[0032] The opening 218 of each pivot part 216 is connected to the main body part 202 by an elastic mounting member 21 It is provided on 7. In this example, the elastic mounting member 217 is integral with the main body portion 202. The elastic mounting member 217 is formed. The elastic mounting member 217 is positioned to bend relative to the main body portion 202. As a result, the cover 204 can be inserted between the pivot parts 216. The process is simplified. In addition, each protrusion 203 on the cover 204 is on the longitudinal surface. It has a surface and sides. The sides are inclined with respect to the longitudinal surface. In other words, the sides are It is not perpendicular to the longitudinal surface. In this way, the protrusion is such that the cover 204 is part of the main body. The elastic mounting member 217 is assisted in bending when it is attached to part 202.

[0033] The main body portion 202 is provided with a recess 220 for receiving the injection device 100. Figure 5 shows the recess. The injection device 100 is located within section 220, and the length of the safety shield 150 is within the recess. It is located in the longitudinal direction within 220. Referring again to Figure 4, the main body portion 202 is It also features a slot 222. The length of the slot 222 is relative to the longitudinal axis of the accessory 200. They are positioned vertically. Slot 222 is the franc of the injection device 100, as shown in Figure 5. It is adapted to accept J155.

[0034] When the cover 204 is in the open position, the recess 220 and slot 222 are located in the injection device 10 It is exposed to receive 0. Specifically, the recess 220 receives the safety shield 150. The slot 222 receives the flange 155. As shown in Figure 6, the injection device 100 When positioned within the recess 220 and slot 222, the cover 204 moves from the open position to the closed position. It is moved to the chain position. The injection device 100 and its accessories 200 are now ready for injection. The setup is complete. The user places the accessory 200, which houses the injection device, on the injection site, for example, on the skin. To administer injections in a safe, simple, and reliable manner, the operating surface 175 is operated with one hand. It can be done.

[0035] When the cover 204 is in the closed position, the cover 204 protects the injection device 100 from the main body portion 20 To hold it in place, the recess 220 and slot 222 are closed. The injection device 100 is covered -When held within the accessory 200 by 204 and the main body portion 202, the injection device 100 This can be seen through the windows 210 provided on each side of the accessory 200. Before administering the injection, the user can examine the contents of the syringe.

[0036] Referring to Figures 4 and 5, slot 222 is distal to the flange 155 of accessory 200. It is molded to resist movement toward end 206. In other words, Lot 222 is molded to prevent flange 155 from moving distally. Slot 222 also moves flange 155 toward the proximal end 208 of attachment 200 It is molded to resist movement. In other words, slot 222 is franc The 155 is molded to prevent it from moving in the proximal direction. However, the slot T222 is that the syringe sheath 120 of the injection device 100 is in the proximal direction relative to the main body portion 202. It is molded to allow movement to the above. As shown, it becomes possible to move from the pre-injection position to the lockout position. In the embodiment, a cavity is formed within the main body portion 202 and the cover 204, and the syringe The creature can move through this cavity. However, the width of this cavity is flat. The 155 cannot move through the cavity, and therefore the cover 204 is in the closed position. While in this position, flange 155 is held within slot 222.

[0037] Referring again to Figure 3, the main body portion 202 and the cover 204 form a pair of opposing sides. They are connected together for this purpose. The right side 212 is shown in Figure 3. The opposite left side is not shown, but the right This is a mirror image of side 212. The accessory 200 has a pair of opposing surfaces. Front surface 214 is shown in Figure 3. The opposing back surfaces are not shown. Each of the opposing surfaces has a similar surface area, and each is... It has a larger surface area than each of the opposing sides. The cover 204 covers a portion of the front 214. The main body portion 202 forms the back surface. These surfaces and sides are the distal end of the accessory 200. The part 206 is connected to the proximal end 208 of the accessory 200.

[0038] The injection device 100 is lowered diagonally into the recess 220, It is positioned at 20. The injection device 100 is positioned in the recess 220. The direction in which 100 is moved toward accessory 200 is perpendicular to the longitudinal axis of accessory 200. The components are arranged in a straight direction, and the components are arranged in a direction parallel to the longitudinal axis of the accessory 200. It has. This direction extends toward the back of the main body portion 202. Specifically, slot 222 and recess 220 are parallel to the surface of accessory 200 from which the injection device 100 is lowered. It has an open surface. The surface of accessory 200 has a larger surface area than the side surface, When positioning the injection device 100 within the accessory 200, the user should target a different area than the accessory 200. It shows a large surface area. This allows users, especially those with dexterity issues, to use the injection device 1 00 can be positioned more easily.

[0039] Referring to Figure 4, the slot 222 has a pair of distal contact portions 2 on both sides of the main body portion 202. It comprises 24. The distal contact portion 224 is fixed to the main body portion 202, and the distal contact portion 224 Each of the flanges resists the distal movement of each of the flanges 155. The distal contact portion 224 is integrally formed with the main body portion 202, making manufacturing easy. , providing a secure connection. However, the main body portion 202 has a distal contact portion 224 that is the main body. It may be a modular component that is removable from part 202. Each distal contact portion 22 4 has a flat upper surface that extends into the curved lower surface. This is on the outside of the lower part of the flange. The shape of the surface is reflected, and the injection device 100 is securely fixed to the main body part 202. We will support you.

[0040] Slot 222 also includes a pair of proximal contact portions 226. The proximal contact portions 226 are Fixed to the body portion 202, one of each of the proximal contact portions 226 is that of the flange 155. Each resists movement in the proximal direction. The proximal contact portion 226 is the main body portion 202 Each is formed integrally, making manufacturing easy and resulting in a secure connection. However, The main body portion 202 has a proximal contact portion 226 that is detachable from the main body portion 202. It may be a Joule-type component. Each proximal contact portion 226 is one of the flanges 155 It has a flat lower surface for interacting with the upper surface. The proximal contact portion 226 is on the syringe sheath 1 They are spaced apart from each other to form a cavity through which 20 can move.

[0041] Referring to Figure 4, the cover 204 has a cover slot 228. Part 228 is when the cover 204 moves from the open position shown in Figure 4 to the closed position shown in Figure 6. Sometimes, it is positioned to hold the flange 155. The cover slot 228 is the cover When 204 is in the closed position, flange 155 faces the distal end 206 of accessory 200. It is molded to resist movement. In other words, cover slot 22 8 is molded to prevent flange 155 from moving distally. Lot 228 also moves flange 155 toward the proximal end 208 of attachment 200 It is molded to resist being flat. In other words, the cover slot 228 is flat The 155 is molded to prevent it from moving in the proximal direction. However, the cover - Slot 228 is the position of the syringe sheath 120 of the injection device 100 relative to the main body portion 202. It is shaped to allow movement in the proximal direction. This allows the injection device 100 to As mentioned above, it becomes possible to move from the pre-injection position to the lockout position. In a particular example, the cover slot 228 works in cooperation with the slot 222 of the main body portion 202. This forms a cavity through which the syringe sheath 120 can pass and move. However, the width of the cavity is Therefore, the flange 155 cannot move through the cavity, and thus the cover 204 is closed. While in the chain position, flange 155 is held within cover slot 228.

[0042] The cover slot 228 also includes a pair of distal contact portions 230 on both sides of the cover 204. The distal contact portion 230 is fixed to the cover 204, and each of the distal contact portions 230 This resists each flange 155 from moving distally. Distal contact portion 230 is integrally formed with cover 204, making it easy to manufacture and providing a secure connection. It brings about. However, the cover 204 is removed from the distal contact portion 230 It may be a removable, modular component. As shown in Figure 4, each distal contact portion 23 0 has ribs that extend along the length of cover 204, and thus structured in cover 204. To provide support.

[0043] The cover slot 228 also includes a pair of proximal contact portions 232. 2 is fixed to cover 204, and one of each of the proximal contact portions 232 is on flange 155 Each resists movement in the proximal direction. The proximal contact portion 232 is the cover 20 Each of the four components is integrally formed, making manufacturing easy and resulting in a secure connection. However, Furthermore, the cover 204 has a proximal contact portion 232 that is removable from the cover 204. It may be a turret-type component.

[0044] Referring to Figures 7 and 8, the accessory 200 extends the needle cap 190 from the injection device 100. It is equipped with a cap removal device 234 for removing the cap. The cap removal device 234 is In this example, a pair of gripping ends for interacting with the needle cap 190 It is equipped with a movable element 236. Each gripping end is attached to the outer surface of the needle cap 190. It is shaped to do so. Each gripping end is joined to the cylindrical outer shape of the needle cap 190. It has a concave end. In this example, the movable element 236 is connected to the cap removal device 234. They are formed as a single unit. However, the movable element 236 is attached to the cap removal device 234. In contrast, they may be provided as separate components that bend or rotate. For example, each movable element 23 6 may be mounted on the cap removal device 234 with the pivot part as the center. Needle cap 190 This may be a rigid needle cap or a non-rigid needle cap. The rigid needle cap is at least It may be formed of two components, for example, a rigid outer shell and when in a given position It may include an inner body surrounding the needle 130 on the syringe 110. The inner body is flexible It may be a side body, an elastic inner body, or a flexible inner body. This inner body is made of rubber. It may also be the side body. Alternatively, a non-rigid needle cap may be used, in which case the needle key A cap is a single flexible body, elastic body, or pliable body, for example, a rubberized needle boot. This may be the case. In the case of a non-rigid needle cap, the cap removal device 234 removes the cap. During removal, for example, the non-rigid needle cap is elastically gripped between a pair of movable elements 236. It is designed to fit in such a way. The cap is not rigid, so the grip is tight and snug. Therefore, to ensure that the cap is removed, the cap removal device 23 It deforms within part 4, especially within the gripping section.

[0045] In this example, the cap removal device 234 has an expanded configuration (as shown in Figure 8) and a contracted configuration. It has a configuration (not shown). In the extended configuration, the cap removal device 234 has a needle cap It does not interact with the pin 190. Specifically, the needle cap 190 does not interact with the cap removal device 2. When 34 is in an extended configuration, for example, when the injection device 100 is inserted into the recess 220 In addition, it can pass through the movable element 236, that is, it can pass through the movable element 236. In this configuration, the cap removal device 234 is connected to the injection device 10 The needle cap 190 is held in place so that it can be removed from the needle cap 190. Specifically, the movable element 236 is connected to the cap removal device 234 via the gripping end of the needle cap To assume a retractable configuration that grips the top 190, they move toward each other. Cover 204 When in the open position, the cap removal device 234 is in the extended position. Close the cover 204. By locking, the cap removal device 234 slides forward to remove the needle cap 190. When removed, it adopts a contracted configuration. However, the cap removal device 234 is (Figure 6) (As shown) When cover 204 is completely closed, release needle cap 190. To do this, we will take on an extended configuration again.

[0046] In this particular example, the gripping portion has two configurations: an expanded configuration and a contracted configuration. However, in another example, the gripping part may be in a retracted configuration by default. In this case, the gripping part The injection device 100 holds the needle cap 190 when it is placed inside the accessory 200, and expands There is no need to transition from a tensioned to a shrunk configuration. This option may make manufacturing simpler. However, when the gripping part takes an expanded configuration, the injection device 100 does not receive resistance from the gripping part. This allows for insertion into accessory 200. In another example, the gripping part is directed toward the non-movable element. It may have only one movable element, such as a push button.

[0047] The cap removal device 234 is positioned within the track of the main body portion 202. It is equipped with a pair of guides 240 that are positioned accordingly. The cap removal device 234 is the main body part It is positioned to slide within track 202.

[0048] Referring to Figures 9 and 10, the cap removal device 234 is a cap removal device Each of the 234 is provided with a pair of cap removal device slots 242. To move the cover 204 from the open position to the closed position, the cover 204 is used by the user. It includes a proximal end 244 that can be moved by a cap removal device 234 and a movable part. To move the gripping portion including element 236 distally, the cover 204 also removes the cap. It includes a distal end 246 that is operably connected to a detachment device 234.

[0049] In this example, a pair of distal ends 246 of the cover 204 are present, and the cap removal device Each of the lots 242 has a cover cam 243 located inside it. As the cover 204 pivots from the open position to the closed position, the cap removal mechanism To translate the position 234 distally, each distal end 246 is a cap removal device slot It connects to one of each of the T242. Figure 11 shows the cover 204 in the closed position. The cap removal device 234 is being moved distally.

[0050] Referring to Figure 9, each cover 204 is positioned distally from each pivot 216. It has a pair of distal extensions that extend outwards. The distal end 246 and the cover cam 243 are distal extensions It is located on the long part. A pair of proximal extensions are provided, each corresponding to one of the distal extensions. It exists. Each proximal extension extends proximally away from each pivot 216, thereby These form two sides of the proximal end 244 of the cover 204.

[0051] Each proximal extension is longer than each distal extension. This is related to the mechanical aspects of the pivot 216. This helps to bring about advantages, and therefore, the cover 204 can be closed more easily. Furthermore, the cap removal device 234 is moved distally to remove the needle cap 190. It is especially important for travel.

[0052] Referring to Figures 8 and 14, one of the movable elements 236 of the gripping section is a flexible elastic It is made of a material. This allows the gripping part to allow the needle cap 190 to pass between the gripping parts. An extended configuration that allows, that is, allows the needle cap 190 to pass through, and the injection device 100 The gripping part is a retractable configuration that holds the needle cap 190 in order to remove it, and can be moved between these two. A cap removal device cam 248 is located on one outer surface of each of the movable elements 236. Each cap removal device cam 248 is connected to the cap removal device 234, which is connected to the cover 204. When moved distally by the main body portion 202, the cap removal device cam surface 2 It connects to 50. The cap removal device cam surface 250 is shown in Figures 12 and 13. The cap removal device 234 also removes the cover 204 when it is in the closed position. It comprises a pair of receptive slots, each adapted to receive at least a portion of the .

[0053] The cap removal device cam 248 is pressed against the cap removal device cam surface 250. Then, the cap removal device 234 moves forward in the distal direction. This expands the gripping portion. To transition from the expanded to the contracted configuration, the movable elements 236 are pushed toward each other. When the injection device 100 is inside the recess 200, the movable element 236 grasps the needle cap 190. It holds. At the same time, the cap removal device 234 is moved distally, therefore Pull the needle cap 190 distally and away from the injection device 100. The needle cap 190 is removed from the injection device 100.

[0054] Referring to Figures 12 and 13, one of the cap removal device cam surfaces 250 When the cover 204 moves from the open position to the fully closed position, the gripping portion expands from its extended configuration. It is molded to transition to a contracted configuration and then back to an expanded configuration. In this example, the cap is removed. Each of the removal device cam surfaces 250 is one of the cap removal device cams 248 Proximal end 252 and distal end 254 that do not interact with one of them, and cap removal device 23 To move the movable element 236 when 4 moves distally, the cap removal device It has an intermediate portion 256 positioned to interact with one of each of the cams 248. ru.

[0055] Figure 8 shows the cover 204 in the fully open position, and the cam removal device 234 in an extended configuration. It is located in Figure 12, which shows the cover 204 in the fully closed position, and the cam removal device is located in the cover - When 204 moves from the fully open position to the fully closed position, it returns from the retracted configuration to the extended configuration. It is.

[0056] Referring to Figure 15, the main body portion 202 is the respective gas of the cap removal device 234 It is equipped with a pair of tracks 258 for receiving Id 240. Each track 258 is for injection When the device 100 is positioned on the main body portion 202, the cap removal device 234 is positioned on the trap. It is fitted so that it does not come out of the container. This is shown in Figure 10. Specifically, the injection device 100 When the injection device 100 is in the recess 220, the cap can be removed from each track 258. Hold device 234.

[0057] Each track 258 is used when the injection device 100 is not located on the main body 202. The top removal device 234 has components that are perpendicular to the axial direction (i.e.) (The accessory 200 moves in the longitudinal direction, extending from the proximal end 208 to the distal end 206.) It is configured so that it is possible. However, the injection device 100 is located in the main body part 202. When positioned, the cap removal device 234 is moved by the injection device 100 to each track 258 It is pressed against, and as a result, the cap removal device 234 is axially positioned relative to the main body portion 202. It can only slide in that direction.

[0058] As shown in Figure 7, each track is when the injection device 100 is positioned in the recess 220. The injection device 100 has a cap removal device 234 inside the track 258, at least partially. At least a portion of the cap removal device 234 is exposed so as to hold it in place. As shown in 10, each track 258 contacts the upper surface of the cap removal device 234. Since it does not include means adapted to such a purpose, track 258 does not include the cap removal device 234 To expose. In other words, the main body part 202 has a cap removal device 2 It does not have a lip or other such retaining means for holding 34. Instead, the injection device 1 00 holds the cap removal device 234 inside the track 258. Specifically, The top removal device 234, when the injection device 100 is positioned in the recess 220, It makes direct contact with 100. This simplifies the design of accessory 200.

[0059] Referring to Figure 15, each track 258 has a base 260 and a cap removal device 23 It comprises a pair of side walls 264, 266 adapted to guide each side of 4. In this example, the pair of side walls 264 and 266 are formed integrally with the main body portion 202. In another example, one or both of the side walls 264, 266 are separate from the main body portion 202. These are components. One of the first side walls 266 of each track 258 is fitted with an injection device 100. When inside item 200, define the wall of window 268 from which the injection device 100 can be seen. One of the second side walls 264 of each track 258 defines the outer side wall of the accessory 200. The base 260 and / or side walls 264, 266 of track 248 are integral with the main body portion 202. It is formed in this way.

[0060] The features of the above accessory 200 are that it is inexpensive, simple, and easy to use. In addition, in order to administer an injection using the injection device 100, the accessory 200 can be operated with one hand. This is possible.

[0061] When using the above injection device, it is used for rheumatoid arthritis, psoriatic arthritis, ankylosing spondylitis, and ulcerative colitis. Colitis, hormone deficiency, poisoning, pain, thrombosis, infection, diabetes, diabetic retinopathy, acute Coronary artery syndrome, angina pectoris, myocardial infarction, atherosclerosis, cancer, macular degeneration, allergy - For the treatment or prevention of hay fever, inflammation, anemia, or myelodysplasia, or for protective immunity Antibodies (monoclonal antibodies, ustekinumab, golimumab, etc.) for use in expression Fliximab, guselkumab, silkumab, adalimumab, rituximab, tocilizumab , centrizumab, centrizumab pegol, sarilumab, secukinumab, ixekizumab , or biosimilar versions thereof, etanercept, abatacept, ana Kinra, epoetin alfa, darbepoetin alfa, epoetin beta-methoxypo Ethylene glycol, peginesatide, hormones, antitoxins, pain control substances, thrombosis control Substances for use, substances for controlling or eliminating infectious diseases, peptides, proteins, human insulin or human Insulin analogs or derivatives, polysaccharides, DNA, RNA, enzymes, oligonucleotides Antiallergic drugs, antihistamines, anti-inflammatory drugs, corticosteroids, disease-modifying anti-inflammatory drugs It contains and is used to deliver substances such as anticoagulants, erythropoietin, or vaccines. Obtain. In addition to these substances, any drugs contained in the infusion device are also as those skilled in the art will understand. It may contain other substances such as inactive ingredients, as is expected. As is well known in the field, certain substances are used in the treatment or prevention of certain conditions. Those skilled in the art will understand that it is effective for this purpose. For example, anti-allergic Ghee drugs are effective in treating or preventing allergies, while antihistamines are used for pollen allergies. It is effective for use in the treatment or prevention of the disease, and anti-inflammatory drugs are used for the treatment or prevention of inflammation. It is known to be effective for [specific purpose]. Therefore, these substances (including multiple substances) are effective. For use in the treatment or prevention of one or more conditions that are known to be, Any selection of one or more substances listed in this specification or in the claims Other options are also conceivable. However, in certain cases, golimumab is used for rheumatoid arthritis , one or more of the following: psoriatic arthritis, ankylosing spondylitis, or ulcerative colitis, Or any combination of rheumatoid arthritis, psoriatic arthritis, ankylosing spondylitis, and ulcerative colitis. , or treatment of all rheumatoid arthritis, psoriatic arthritis, ankylosing spondylitis, and ulcerative colitis or It is known to be effective for use in prevention.

[0062] Golimumab contains L-histidine, L-histidine monohydrochloride monohydrate, sorbitol, and One or more inactive ingredients, such as Resorbate 80 and water, or all of them. It may be used in combination with other substances as desired. Golimumab is the sole active ingredient. It may be present in a certain composition. For example, golimumab may be SIMPONI®. It may be administered.

[0063] The term "comprising" includes "including" and "consisting of". "Consisting" means "to include," for example, a combination of "compositions" that "include" X. The resulting product may consist exclusively of X, and may include some additional components such as X + Y. Unless otherwise stated, each embodiment described herein is a different embodiment described herein. It may be combined with other forms. In the specific embodiment described above, in order to achieve a specific function, We provided pairs of components. However, at least one of these components These functions can be achieved using this method.

[0064] The above benefits and advantages may relate to one embodiment or to several embodiments. It will be understood that they may be linked. The embodiments may address any or all of the problems described. Limited to those that resolve the issue or have any or all of the stated benefits and advantages. It is not done. A reference to an item "an" refers to one or more of those items. .

[0065] The above description of preferred embodiments is given merely as examples and will be understood by those skilled in the art. It will be understood that various modifications may be made. Various embodiments, to a certain extent. As described above with respect to the specific characteristics of one or more individual embodiments, This involves making numerous modifications to the disclosed embodiments without departing from the scope of the present invention. It is possible.

[0066] List of numbered embodiments 1. Accessories for an injection device, the injection device includes a safety shield and a user-held injection device. At least one flange adapted to hold, and at least one flange It has a syringe sheath that is movable from the pre-injection position to the lockout position, and the accessories are , A recess adapted to receive the safety shield of the injection device, and at least one of the injection device A body portion comprising a slot adapted to receive two flanges, A cover connected to the main body, the cover having a recess and a slot exposed for the injection device The safety shield and flange are positioned in open positions, respectively, and the cover has recesses and slots. A closed position that holds the injection device to the main body by at least partially closing the valve, and a pivot between these two positions. It is possible, and equipped with a cover, The slot is such that at least one flange moves distally and proximal to the main body. It resists movement, and the syringe sheath moves from the pre-injection position to the lockout position. An accessory molded to move proximal to the minute. 2. The distal end of the accessory, which is adapted to be positioned toward the injection site, and the opposing The proximal end of the accessory, A pair of opposing surfaces and a pair of opposing side surfaces connecting the distal and proximal ends of the accessory, further The accessories described in Embodiment 1 are provided. 3. Each of the opposing surfaces has a larger surface area than each of the opposing sides. Accessories as described in Embodiment 2. 4. An accessory according to Embodiment 2 or Embodiment 3, wherein one of the opposing surfaces is provided with a cover. . 5. Each of the slots and recesses has an open surface that is parallel to the surface of the accessory, in the embodiment The accessory listed in one of items 2-4. 6. The recesses and slots are positioned so that the injection device is perpendicular to the longitudinal axis of the accessory. According to any one of Embodiments 1 to 5, the device is positioned to receive an injection device when it is in motion. Accessories. 7. The slot is such that at least one flange moves distally relative to the accessory. Embodiments 1 to 6 each have at least one distal contact portion positioned to resist the force. The accessories listed in one of the following items. 8. At least one distal contact portion of the slot is integrally formed with the main body portion. Accessories as described in Installation Form 7. 9. The shape of at least one distal contact portion is the shape of at least one lower surface of a flange. An accessory according to Embodiment 7 or Embodiment 8, which at least partially matches the accessory described above. 10. The slot is such that at least one flange moves proximally relative to the accessory. Embodiments 1 to include at least one proximal contact portion positioned to resist and The accessories listed in any one of the 9 items. 11. At least one proximal contact portion of the slot is integrally formed with the main body portion. Accessories as described in Embodiment 10. 12. The cover has at least one flange distally and proximal to the accessory. Although it resists movement, the syringe sheath moves from the pre-injection position to the lockout position. The implement includes a cover slot that is molded to allow movement in the proximal direction relative to the accessory. The accessories listed in one of Forms 1-11. 13. The accessory according to Embodiment 12, wherein the cover slot is formed inside the cover. 14. The cover slot is such that at least one flange moves distally relative to the accessory. An implementation comprising at least one distal contact portion positioned to resist doing so Accessories as described in item 13. 15. At least one distal contact portion of the cover slot is integrally formed with the cover. The accessories described in Embodiment 14. 16. The cover slot is such that at least one flange moves proximal to the accessory. An implementation comprising at least one proximal contact portion positioned to resist doing so Accessories listed in one of the following conditions (12-15). 17. At least one proximal contact portion of the cover slot is integrally formed with the cover. The accessories described in Embodiment 16. 18. The accessories are a pair of fittings adapted to allow the user to grasp the injection device. An accessory according to any one of embodiments 1 to 17, for use with an injection device having a flange. 19. The slot is located distal to the accessory, with each flange of the pair of flanges positioned distally to the accessory. The implement comprises a pair of distal contact portions, each positioned to resist movement. Accessories as described in Form 18. 20. The pair of distal contact portions are integrally formed with the main body portion, as described in Embodiment 19. accessories. 21. The shape of each of the pair of distal contact portions is the same as the shape of each of the pair of flanges. The lower surface shape of the attachment described in Embodiment 19 or Embodiment 20, which at least partially matches the shape of the lower surface. Accessories. 22. The slots are located in the direction of each flange of the pair of flanges, proximal to the main body. A real Accessories as described in one of the installation configurations 18-21. 23. The pair of proximal contact portions are integrally formed with the main body portion, as described in Embodiment 22. accessories. 24. The cover slot is formed by the distal movement of a pair of flanges relative to the main body. Embodiments 18 to 23 each have a pair of distal contact portions arranged to resist the force The accessories listed on one of the items. 25. The pair of distal contact portions of the cover slot are integrally formed with the cover, Accessories as described in item 24. 26. The cover slot is formed by the movement of a pair of flanges in a proximal direction relative to the main body. Embodiments 18 to 25 each include a pair of proximal contact portions arranged to resist the force The accessories listed on one of the items. 27. The pair of proximal contact portions of the cover slot are integrally formed with the cover, Accessories as described in item 26. 28. The cap removal device further comprises a gripping portion, and the cap removal device is: An extended configuration in which the needle cap of the firing device can pass between the gripping parts, and the gripping parts can hold the needle cap It has a shrinking mechanism that holds and at least partially removes the needle cap from the injection device, An accessory as described in any one of Embodiments 1 to 27. 29. The cover and cap removal device moves the cover from the open position to the closed position. When moved, the cap removal device can be operated to transition from an extended configuration to a retracted configuration. Accessories according to embodiment 28, which are connected to each other. 30. The cap removal device returns to its extended configuration when the cover reaches the closed position, and the needle An accessory according to embodiment 28 or embodiment 29, which is positioned to release the cap. 31. The gripping part holds the needle cap when the cap removal device is in its retracted configuration. The cap removal device is offset from the needle cap when it is in the extended configuration. One of embodiments 28 to 30, comprising a adapted, at least one movable element. The accessories listed. 32. At least one movable element is formed from a flexible elastic material, and the flexible elastic material The material has at least one movable element, in a position where the gripping part holds the needle cap, and the needle cap The attachment described in Embodiment 31 is movable between a position where it can pass between the gripping parts and Product. 33. At least one movable element is positioned such that the gripping part holds the needle cap, and the needle cap The implement is configured to bend between the gripping parts in a position where it can pass between them. Accessories as described in Form 32. 34. To transition the cap removal device from the expanded configuration to the contracted configuration, at least Another cap removal device is positioned to interact with the cam surface, at least one One of embodiments 28 to 33 further comprises a cap removal device cam. Accessories. 35. At least one cap removal device cam is connected to at least one movable element. Embodiments 31 and 3 are connected or provided on at least one movable element. 4. Accessories as described in Embodiment 32 and / or Embodiment 33, optionally. 36. The cap removal device cam surface is connected to the main body or on the main body. An accessory provided as described in Embodiment 34 or Embodiment 35. 37. At least one cap removal device cam surface is a cap removal device cam As it moves across the surface of the cap removal device cam, the cap removal device expands as it passes through. To transition from a taut configuration to a deflated configuration and then back to an expanded configuration, the cap removal device cam and An accessory according to any one of embodiments 34 to 36, arranged to interact with each other. 38. At least one cap removal device cam and at least one cap removal The cam surfaces of the removal device are offset from each other when the cover is in the open position, in practice. Accessories listed in one of the following descriptions (34-37). 39. The movement of the cover from the open position to the closed position moves the cap removal device cam. The cap removal device engages with the cam surface, and as a result, the cap removal device expands An accessory according to any one of embodiments 34 to 38, which transitions from a solid to a shrinkable configuration. 40. The gripping portion is molded to match the outer surface of the needle cap, at least one An accessory according to any one of embodiments 28 to 39, comprising a gripping end. 41. The gripping part holds the needle cap when the cap removal device is in its retracted configuration. The cap removal device is offset from the needle cap when it is in the extended configuration. An attachment described in any one of embodiments 28 to 40, comprising a pair of movable elements that are adapted. Product. 42. Each of the pair of movable elements is formed from a flexible elastic material, and is flexible elastic The material is such that each movable element is positioned such that the gripping part holds the needle cap, and the needle cap is part of the gripping part An accessory as described in Embodiment 41, which is movable between a position that can pass through and a position that can move between two positions. 43. Each of the pair of movable elements has a position where the gripping part holds the needle cap and the needle key The cap is configured to bend between a position where it can pass between the gripping parts. Accessories as described in Embodiment 41 or Embodiment 42. 44. A pair of soles are used to transition the cap removal device from an expanded configuration to a contracted configuration. Each is positioned to interact with one of the surfaces of the cap removal device cam. Any one of embodiments 28 to 38 further comprises a pair of cap removal device cams. Accessories as listed below. 45. Each cap removal device cam is connected to one of the movable elements. Alternatively, they are provided on each of the movable elements, Embodiment 41, Embodiment 4 4, and optionally the accessories described in Embodiment 42 and / or Embodiment 44. 46. ​​The cam surface of each cap removal device is connected to the main body or on the main body. An accessory provided in the embodiment 44 or embodiment 45. 47. The surface of the cap removal device cam is such that the cap removal device cam is on each cap The cap removal device moves along the surface of the cam, and as it passes, the cap removal device expands its configuration. Embodiments 44-46 are arranged to transition from a contracted configuration to an expanded configuration and then back to an expanded configuration. The accessories listed in one of the items. 48. Each cap removal device cam and the corresponding cap removal device cam surface are The bars are offset from each other when in the open position, and as a result, the cap removal process The cam and cap removal device are not joined to each other, in any of embodiments 44 to 47. Accessories listed on one item. 49. The movement of the cover from the open position to the closed position is controlled by each cap removal device. Move the cam to engage with the corresponding cap removal device cam surface, and as a result, the cap is removed. The removal device transitions from an extended configuration to a retracted configuration, in any one of embodiments 44 to 48. The accessories listed. 50. The gripping portions are a pair, each molded to match the outer surface of the needle cap. An accessory according to any one of embodiments 28 to 59, comprising a gripping end. 51. Cap remover with a gripping portion adapted to hold the needle cap of an injection device. The embodiment further includes a removal device, the cap removal device being movable relative to the main body. The accessory listed in one of the numbers from 1 to 50. 52. The cover is, In order to move the cover from the open position to the closed position, it is subject to user interaction. The end portion and When the cover moves from the open position to the closed position, the gripping part moves towards the end of the accessory. To remove the needle cap, at least partially, from the syringe. The accessory according to embodiment 51, comprising a distal end operably connected to the device. 53. The cover is connected to the main body portion around at least one pivot point, Embodiment 5 Accessories as described in item 2. 54. At least one pivot part, At least one opening in the main body, At least one protrusion within the cover, the at least one protrusion within the opening The accessory according to embodiment 53, comprising at least one rotatable projection. 55. The cover extends distally from at least one pivot, at least It has one distal extension, and the distal end of the cover is provided at the end of the distal extension, Accessories as described in embodiment 53 or embodiment 54. 56. The cover has a proximal extension that extends proximally away from at least one pivot point. The accessories provided are those described in any one of embodiments 53 to 55. 57. The distal extension is shorter than the proximal extension, as described in Embodiments 55 and 56. accessories. 58. The distal end of the cover is located within the cap removal device slot of the cap removal device. An accessory according to any one of embodiments 52 to 57, comprising a cover cam positioned at [location]. 59. To move the cap removal device within the accessory, a cover is used with a pivot axis. - The rotation of the cam causes the cover cam to act against the cap removal device slot. Accessories as described in Installation Form 58. 60. To move the cap removal device toward the distal end of the accessory, the cover is It pivots from the open position to the closed position, and covers the cap removal device slot. An accessory according to embodiment 58 or embodiment 59, which is arranged to actuate the cam. 61. The gripping part is such that the cap removal device slot moves toward the distal end of the accessory. While doing so, hold the needle cap and remove it at least partially from the syringe. The accessory described in embodiment 60, which is arranged in the same manner. 62. To move the cap removal device toward the proximal end of the accessory, the cover is It pivots from the closed position to the open position, and covers the cap removal device slot. An accessory, as described in any one of embodiments 58 to 61, arranged to actuate the cam. . 63. The cover is connected to the main body by a pair of pivots, as in Embodiments 52-62. The accessories listed in one of the items. 64. Each of the pair of pivot parts comprises an opening in the main body and a protruding part inside the cover. The accessory according to embodiment 63, wherein the protruding portion is rotatable within the opening. 65. The cover extends distally from each of the pair of pivots. The accessory according to embodiment 63 or embodiment 64, comprising a pair of distal extensions. 66. The cover extends proximal to each of the pair of pivots. An accessory according to any one of embodiments 63 to 65, comprising a pair of proximal extensions. 67. Embodiments 65 and 6, in which each distal extension is shorter than the corresponding proximal extension. Accessories as described in item 6. 68. A pair of distal ends of the cover, each provided at one end of the distal extension. It further comprises a section, one of which at each distal end, the cover moves from an open position to a closed position. Then, move the gripping part toward the end of the accessory and remove the needle cap from the injection device at least Embodiment 65, which is operably connected to a cap removal device to partially remove the cap, And optionally, the accessories described in Embodiment 66 and / or Embodiment 67. 69. Each distal end of the cover is the corresponding cap removal device. The accessory according to embodiment 68, comprising a cover cam positioned within a removal device slot. 70. To move the cap removal device within the accessory, each of the pivots around the pivot axis The rotation of the bar cam opposes the corresponding cap removal device slot for each cover An accessory described in embodiment 69 for operating the cam. 71. To move the cap removal device toward the distal end of the accessory, the cover is It pivots from the open position to the closed position, opposing the corresponding cap removal device slot. The cover cams are arranged to act in accordance with Embodiment 69 or Embodiment 70. accessories. 72. The gripping part is such that the cap removal device slot moves toward the distal end of the accessory. The needle cap is held in place while the needle cap is removed from the injection device. Accessories as described in Installation Form 71. 73. To move the cap removal device toward the proximal end of the accessory, the cover is It pivots from the closed position to the open position, opposing the corresponding cap removal device slot. As described in any one of embodiments 69 to 72, each cover cam is positioned to act. Included accessories. 74. The main body is equipped with tracks arranged so that the cap removal device moves in a translating manner. , The truck is located inside the truck when the syringe is positioned in the recess. The cap removal device is held at least partially, An accessory according to any one of embodiments 1 to 73, which also exposes a portion of itself. 75. The track is such that when the injection device is positioned in the recess, the cap removal device is An accessory according to embodiment 74, configured to be in direct contact with an injection device. 76. The track is equipped with means adapted to contact the upper surface of the cap removal device. Accessories described in Embodiment 74 or Embodiment 75 are not permitted. 77. The track comprises a base and at least one side wall, according to embodiments 74-76. The accessories listed in one of the items. 78. The track is, A base adapted to guide the underside of the cap removal device, At least one side wall adapted to guide the side of the cap removal device, An accessory according to any one of embodiments 74 to 77, comprising: 79. At least one side wall is visible when the syringe is inside the accessory. An accessory according to embodiment 78 that defines the wall of a window where it can be made. 80. At least one side wall defines the outer side wall of the accessory, as described in Embodiment 78. Accessory 81. The base and / or at least one side wall is integrally formed with the body part, the implementation The accessory according to any one of Embodiments 78 to 80 82. The track is adapted to guide each side surface of the cap removal device The accessory according to any one of Embodiments 78 to 81, comprising a pair of side walls 83. The pair of side walls is integrally formed with the body part, the implementation of any one of Embodiments 78 to 82 One of the accessories described 84. The body part includes a pair of tracks arranged such that the cap removal device translates Each track is configured such that when the injection device is positioned in the recess, the injection device holds at least a portion of the cap removal device within each track To at least partially expose the cap removal device, the accessory according to any one of Embodiments 74 to 83 At least a part of the cap removal device is exposed The accessory according to any one of Embodiments 74 to 83 85. Each track is configured such that when the injection device is positioned in the recess, the cap removal device Is in direct contact with the injection device, the accessory according to Embodiment 84 86. Each track does not include means adapted to contact the upper surface of the cap removal device The accessory according to Embodiment 84 or Embodiment 85 87. Each track includes a base and at least one side wall, the implementation of any one of Embodiments 84 to 86 One of the accessories described 88. Each track is A base adapted to guide the lower surface of the cap removal device At least one side wall adapted to guide the side surface of the cap removal device The accessory according to any one of Embodiments 84 to 87 89. At least one side wall of each track is such that when the injection device is within the accessory, the injection device An accessory according to embodiment 88 that defines the wall of a window from which the interior can be seen. 90. Each track has at least one side wall that defines the outer side wall of the accessory, Embodiment Accessories as listed on item 88. 91. The base and / or at least one side wall of each track is formed integrally with the main body. The accessory described in any one of embodiments 88 to 90. 92. Each track is fitted to guide each side of the cap removal device. An accessory according to any one of embodiments 88 to 91, comprising a pair of side walls. 93. The pair of side walls of each track are formed integrally with the main body portion, as in Embodiments 88-9 The accessories listed in one of item 2. 94. The cap removal device is fitted with a guide so that it can be positioned inside the truck. An accessory according to any one of embodiments 74 to 93, comprising: 95. The cap removal device, when the cover is in the closed position, removes at least the cover. Embodiment comprising at least one receptive slot adapted to receive a portion The accessory listed in one of the numbers 1 through 94. 96. The cap removal device, when the cover is in the closed position, removes at least the cover Embodiment 1 comprises a pair of receiving slots, each adapted to receive a portion. Accessories listed in any one of the ~95 items. 97. The main body is fitted to connect the cover to the main body, at least one An accessory according to any one of embodiments 1 to 96, comprising an elastic mounting member. 98. The main body is designed so that the cap removal device moves axially relative to the main body. It is equipped with a track that is positioned in the main body when the injection device is in position. The top removal device is adapted to be pressed against the truck by the injection device. An accessory as described in any one of Embodiments 1 to 97. 99. The track is located in the main body when the injection device is in position. An accessory as described in Embodiment 100, which is fitted to prevent it from coming loose from the rack. 100. The track is the cap removal device when the injection device is not positioned in the main body. However, it is adapted to be movable in a direction having components that are perpendicular to the axial direction. Accessories as described in embodiment 100 or embodiment 101. 101. The track is such that when the injection device is positioned in the main body, the cap removal device is The injection device presses against the truck, and as a result, the cap removal device is pressed against the main body Embodiments 100-10 are adapted to allow movement only in the axial direction relative to the minute. The accessories listed in one of item 2. 102. The main body is equipped with tracks on which the cap removal device slides. The accessories described in any one of embodiments 1 to 101. 103. At least one cap removal device cam is a cap removal device cam table. The surface is arranged to slide within the slot of the main body portion that accommodates the surface, Embodiment 1 and the embodiment Embodiment 34, and optionally one of Embodiments 2 to 33 and Embodiments 35 to 102 Accessories as listed. 104. A system for administering injections, the system comprising an injection device and Embodiment 1~ A system comprising the accessories listed in any one of 103. 105. The injection device is Rheumatoid arthritis, psoriatic arthritis, ankylosing spondylitis, ulcerative colitis, hormone deficiency poisoning, pain Pain, thrombosis, infection, diabetes, diabetic retinopathy, acute coronary syndrome, angina pectoris, myocardial infarction, For the treatment or prevention of atherosclerosis, cancer, macular degeneration, allergy, hay fever, inflammation, anemia, or myelodysplasia, or for use in the expression of defensive immunity, an antibody (mono clonal antibody, ustekinumab, golimumab, infliximab, guselkumab, sir cumab, adalimumab, rituximab, tocilizumab, certolizumab, certolizumab pegol, sarilumab, secukinumab, ixekizumab, or a biosimilar thereof such as John), etanercept, abatacept, anakinra, epoetin alfa, darb epoetin alfa, epoetin beta-methoxypolyethylene glycol, peginesatide, hormone, antitoxin, pain control substance, thrombosis control substance, infection control or elimination substance, peptide, protein, human insulin or human insulin analog or derivative, polysaccharide, DNA, RNA, enzyme, oligonucleotide, anti-allergy drug, antihistamine drug anti-inflammatory drug, corticosteroid, disease-modifying antirheumatic drug, erythropoietin, or vaccine, a system according to embodiment 104 containing a substance selected from the group consisting of. 106. A substance, made by delivery of a substance to a human subject using the system according to embodiment 104 where the substance is for the treatment or prevention of rheumatoid arthritis, psoriatic arthritis, ankylosing spondylitis, ulcerative colitis, hormone deficiency poisoning, pain, thrombosis, infection, diabetes, diabetic retinopathy, acute coronary syndrome, angina pectoris, myocardial infarction, atherosclerosis, cancer, macular degeneration, allergy, hay fever, inflammation, anemia, or myelodysplasia, or for use in the expression of defensive immunity, an anti body (monoclonal antibody, ustekinumab, golimumab, infliximab, guselkumab Br, silukumab, adalimumab, rituximab, tocilizumab, centrizumab, centrizumab Lizumab pegol, sarilumab, secukinumab, ixekizumab, or these biosimilar (e.g., Ra version), etanercept, abatacept, anakinra, epoetinalph a, darbepoetin alpha, epoetin beta-methoxypolyethylene glycol, pe Guinesatide, hormones, antitoxins, pain control substances, thrombosis control substances, infection control or Elimination substances, peptides, proteins, human insulin or human insulin analogs or Derivatives, polysaccharides, DNA, RNA, enzymes, oligonucleotides, antiallergic drugs, antihistamines Vitamins, anti-inflammatory drugs, corticosteroids, disease-modifying antirheumatic drugs, erythropoietin A substance selected from the group consisting of, or vaccines. 107. Using the system described in Embodiment 104, antibodies to human subjects (Monoclonal antibodies, ustekinumab, golimumab, infliximab, guselkumab) , silukumab, adalimumab, rituximab, tocilizumab, centrizumab, centr Zumab pegol, sarilumab, secukinumab, ixekizumab, or these biosimilars (Versions etc.), etanercept, abatacept, anakinra, epoetin alpha Darbepoetin alpha, epoetin beta-methoxypolyethylene glycol, Pegy Nesatides, hormones, antitoxins, pain control substances, thrombosis control substances, infection control or elimination Decontaminating substances, peptides, proteins, human insulin or human insulin analogs or inducers Conductors, polysaccharides, DNA, RNA, enzymes, oligonucleotides, anti-allergic drugs, antihistamines Min drugs, anti-inflammatory drugs, corticosteroids, disease-modifying antirheumatic drugs, erythropoietin, Rheumatoid arthritis, psoriatic arthritis, by delivery of a substance selected from the group consisting of or vaccines. Ankylosing spondylitis, ulcerative colitis, hormone deficiency poisoning, pain, thrombosis, infections, diabetes, Diabetic retinopathy, acute coronary syndrome, angina pectoris, myocardial infarction, atherosclerosis, cancer, Treatment or prevention of macular degeneration, allergies, hay fever, inflammation, anemia, or myelodysplasia An injection device for use in the expression of protective immunity.

Claims

1. An accessory for an injection device, wherein the injection device comprises a safety shield and a user-operated injection device At least one flange adapted to grip the and the at least one flange The syringe has a movable syringe sheath that moves from the pre-injection position to the lockout position relative to the syringe. The aforementioned accessories are, A recess adapted to receive the safety shield of the injection device, and the injection device Body portion comprising a slot adapted to receive at least one flange and, A cover connected to the main body portion, wherein the cover has the recess and the slot The opening is exposed and receives the safety shield and flange of the injection device, respectively. The cover then partially closes the recess and the slot, and the syringe It comprises a cover that is pivotable between a closed position that holds the object in the main body portion and a closed position, The slot is such that the at least one flange is distal to the main body portion and It resists moving in the proximal direction, and the syringe sheath moves from the pre-injection position to the lower It is molded to be able to move proximal to the main body portion towards the checkout position. accessories.

2. The distal end of the accessory, which is adapted to be positioned toward the injection site, and the opposing The proximal end of the aforementioned accessory, A pair of opposing surfaces, and a pair of connecting the distal end and proximal end of the accessory. The accessory according to claim 1, further comprising a facing side and

3. Each of the opposing surfaces has a larger surface area than each of the opposing surfaces. The accessory described in claim 2.

4. The accessory according to claim 2 or 3, wherein one of the opposing surfaces is provided with the cover. 。

5. The slot and the recess each have an open surface that is parallel to the surface of the accessory. or an accessory as described in any one of claims 2 to 4.

6. The recess and the slot are such that the injection device is perpendicular to the longitudinal axis of the accessory. Arranged to receive the injection device when moving in a certain direction, any of claims 1 to 5 Accessories as listed in any one of the items.

7. The slot allows at least one flange to move distally relative to the accessory. A claim comprising at least one distal contact portion arranged to resist doing so, Accessories listed in any one of items 1 to 6.

8. The at least one distal contact portion of the slot is integrally formed with the main body portion. The accessory described in claim 7.

9. The shape of the at least one distal contact portion is below the at least one flange. The accessory according to claim 7 or claim 8, which at least partially matches the shape of the surface.

10. The slot allows the at least one flange to move proximal to the accessory. A claim comprising at least one proximal contact portion positioned to resist doing so, Accessories listed in any one of items 1 through 9.

11. The at least one proximal contact portion of the slot is integrally formed with the main body portion. The accessory described in claim 10.

12. The cover is such that the at least one flange is distal and proximal to the accessory. Although it resists moving in the direction, the syringe sheath moves from the pre-injection position to the lock A cover molded to move proximal to the aforementioned accessory in the out position. An accessory according to any one of claims 1 to 11, comprising a slot.

13. The cover slot is formed within the cover, as described in claim 12.

14. The cover slot is located distal to the accessory, with at least one flange positioned distal to the accessory. It comprises at least one distal contact portion positioned to resist movement, The accessory described in claim 13.

15. The at least one distal contact portion of the cover slot is integrally formed with the cover. The accessory described in claim 14.

16. The cover slot is such that the at least one flange is in the proximal direction relative to the accessory. It comprises at least one proximal contact portion positioned to resist movement, The accessory according to any one of claims 12 to 15.

17. The at least one proximal contact portion of the cover slot is integrally formed with the cover. The accessory described in claim 16.

18. The aforementioned accessories include a pair of flanges adapted to allow the user to grasp the injection device. An accessory according to any one of claims 1 to 17, for use with an injection device.

19. The slot is located distal to the accessory where each flange of the pair of flanges is distal to the accessory. It comprises a pair of distal contact portions, each positioned to resist movement in a particular direction. , the accessory described in claim 18.

20. The pair of distal contact portions are integrally formed with the main body portion, as described in claim 19. accessories.

21. The shape of each of the pair of distal contact portions is the shape of each of the pair of flanges The shape of the lower surface of the lunge, as described in claim 19 or claim 20, which at least partially matches the shape of the lower surface of the lunge. accessories.

22. The slot is such that each flange of the pair of flanges is close to the main body portion. It comprises a pair of proximal contact portions, each positioned to resist movement in the lateral direction. The accessory described in any one of claims 18 to 21.

23. The pair of proximal contact portions are integrally formed with the main body portion, as described in claim 22. accessories.

24. The cover slot is such that the pair of flanges move distally relative to the main body portion. Claims 18 to 23, comprising a pair of distal contact portions arranged to resist the action Accessories listed in any one of the items.

25. The pair of distal contact portions of the cover slot are integrally formed with the cover. The accessory described in claim 24.

26. The cover slot is such that the pair of flanges move in a direction proximal to the main body portion. Claims 18 to 25, comprising a pair of proximal contact portions arranged to resist the action Accessories listed in any one of the items.

27. The pair of proximal contact portions of the cover slot are integrally formed with the cover. The accessory described in claim 26.

28. A system for administering injections, the system comprising a safety shield, and the user, the injection At least one flange adapted to grip the injection device, and the at least one A cylinder that is movable from the pre-injection position to the lockout position relative to one flange The injection device having an injection sheath and the accessory described in any one of claims 1 to 27 A system to prepare.

29. The injection device is Rheumatoid arthritis, psoriatic arthritis, ankylosing spondylitis, ulcerative colitis, hormone deficiency poisoning, pain Pain, thrombosis, infection, diabetes, diabetic retinopathy, acute coronary syndrome, angina pectoris, myocardial infarction, Atherosclerosis, cancer, macular degeneration, allergies, hay fever, inflammation, anemia, or Antibodies (mono) for use in the treatment or prevention of myelodysplasia, or for the expression of protective immunity. Clonal antibodies, ustekinumab, golimumab, infliximab, guselkumab, sil Kumab, adalimumab, rituximab, tocilizumab, centrizumab, centrizumab Pegol, sarilumab, secukinumab, ixekizumab, or biosimilar bars of these. John, et al., etanercept, abatacept, anakinra, epoetin alfa, dal Bepoetin alpha, epoetin beta-methoxypolyethylene glycol, Peginesati D, hormones, antitoxins, pain control substances, thrombosis control substances, substances for controlling or eliminating infections Proteins, peptides, proteins, human insulin or human insulin analogs or derivatives, Polysaccharides, DNA, RNA, enzymes, oligonucleotides, antiallergic drugs, antihistamines , anti-inflammatory drugs, corticosteroids, disease-modifying antirheumatic drugs, erythropoietin, or The system according to claim 28, comprising a substance selected from the group consisting of cutin.

30. A substance, the delivery of said substance to a human subject using the system described in claim 28. This is done by the substance, which is used in rheumatoid arthritis, psoriatic arthritis, ankylosing spondylitis, and ulcerative colon. Inflammation, hormone deficiency poisoning, pain, thrombosis, infection, diabetes, diabetic retinopathy, acute coronary artery disease Syndrome, angina pectoris, myocardial infarction, atherosclerosis, cancer, macular degeneration, allergies, flowers For the treatment or prevention of pollen allergies, inflammation, anemia, or myelodysplasia, or for the development of protective immunity. Antibodies for use (monoclonal antibodies, ustekinumab, golimumab, inflix) Simab, guselkumab, silukumab, adalimumab, rituximab, tocilizumab, sen Tolizumab, centrizumab pegol, sarilumab, secukinumab, ixekizumab, or These biosimilar versions include etanercept, abatacept, and anakinra. , epoetin alpha, darbepoetin alpha, epoetin beta-methoxypolyethylene Lenglycol, peginesatide, hormones, antitoxins, pain control substances, thrombosis control substances , substances for controlling or eliminating infectious diseases, peptides, proteins, human insulin or human insulin Phosphorus analogs or derivatives, polysaccharides, DNA, RNA, enzymes, oligonucleotides, anti-phosphorus compounds Allergy medications, antihistamines, anti-inflammatory drugs, corticosteroids, disease-modifying antirheumatic drugs , erythropoietin, or vaccine A substance selected from the group consisting of the following.

31. By using the system described in claim 28, an antibody (monoclorose) can be applied to a human subject. Naru antibody, ustekinumab, golimumab, infliximab, guselkumab, silkumab Adalimumab, rituximab, tocilizumab, centrizumab, centrizumab pegol sarilumab, secukinumab, ixekizumab, or their biosimilar versions (etc.), etanercept, abatacept, anakinra, epoetin alpha, dalbepoe Chin alpha, epoetin beta-methoxypolyethylene glycol, peginesatide, ho Lumon, antitoxins, pain control substances, thrombosis control substances, infection control or elimination substances, Butides, proteins, human insulin or human insulin analogs or derivatives, polysaccharides DNA, RNA, enzymes, oligonucleotides, anti-allergic drugs, antihistamines, anti-inflammatory drugs Symptomatic drugs, corticosteroids, disease-modifying antirheumatic drugs, erythropoietin, or vaccines Delivery of a substance selected from the group consisting of the following is used to treat rheumatoid arthritis, psoriatic arthritis, and ankylosing spine. Inflammation, ulcerative colitis, hormone deficiency poisoning, pain, thrombosis, infection, diabetes, diabetic retina Coronary artery disease, acute coronary syndrome, angina pectoris, myocardial infarction, atherosclerosis, cancer, macular degeneration, For the treatment or prevention of allergies, hay fever, inflammation, anemia, or myelodysplasia, or for prevention An injection device used for inducing immunity.

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