Cosmetics

Abstract

Providing a cosmetic that is not sticky, has excellent skin affinity, and has a smooth feeling. 【Solution means】The cosmetic according to the present disclosure contains (A) 0.1% by mass to 5% by mass of a glycine derivative represented by formula (1) or a salt thereof, (B) niacin or a derivative thereof, (C) a higher alcohol having 14 to 22 carbon atoms, (D) a hydrophilic polyoxyethylene alkyl ether, and (E) a glycerin monoalkyl ether. TIFF2026105749000006.tif43169 (In the formula, R 1 and R 2 each independently represents H, an alkyl group, an alkenyl group, an aryl group, an aralkyl group, an aminomethylcarbonyl group, an amidino group, an alkylcarbonyl group, an alkenylcarbonyl group, etc., and R 3 represents H, an alkyl group, an alkenyl group, an aryl group, or an aralkyl group. However, R 1 , R 2 , R 3 do not simultaneously become H.)

Description

[Technical Field]

[0001] This disclosure relates to cosmetics. [Background technology]

[0002] Oil-in-water emulsions are favored as cosmetic bases because their outer phase (continuous phase), i.e., the phase that first touches the skin, is the aqueous phase, resulting in a refreshing feel. Various attempts are being made to improve these oil-in-water emulsion bases to create cosmetics with an even better feel, while taking advantage of their characteristics.

[0003] For example, it has been disclosed that an oil-in-water emulsion composition containing a higher alcohol, a polyoxyethylene alkyl ether, and a glycerin monoalkyl ether in specific ratios has a refreshing, non-sticky feel and can also provide excellent firmness (see Patent Document 1).

[0004] On the other hand, niacinamide, a type of vitamin B, is used as an ingredient in topical medications to treat acne (acne vulgaris) and is also incorporated into cosmetics for cosmetic purposes. In Japan, it is approved as an effective ingredient in quasi-drug cosmetics for improving blemishes and wrinkles. It is known that niacinamide needs to be included at a concentration of 3% by mass or more to improve blemishes and wrinkles. [Prior art documents] [Patent Documents]

[0005] [Patent Document 1] Japanese Patent Publication No. 2012-31088 [Overview of the project] [Problems that the invention aims to solve]

[0006] The objective of this disclosure is to provide a cosmetic product that is non-sticky, blends well with the skin, and has a smooth feel. [Means for solving the problem]

[0007] To solve the above problems, the cosmetic composition according to this disclosure contains (A) 0.1% to 5% by mass of a glycine derivative represented by formula (1) or a salt thereof, (B) niacin or a derivative thereof, (C) a higher alcohol having 14 to 22 carbon atoms, (D) a hydrophilic polyoxyethylene alkyl ether, and (E) a glycerin monoalkyl ether.

[0008] [ka] (In the formula, R 1 and R 2 Each of these independently represents a hydrogen atom, an alkyl group, an alkenyl group, an aryl group, an aralkyl group, an aminomethylcarbonyl group, an amidino group, an alkylcarbonyl group, an alkenylcarbonyl group, an arylcarbonyl group, or an aralkylcarbonyl group, and R 3 R represents a hydrogen atom, an alkyl group, an alkenyl group, an aryl group, or an aralkyl group. However, the R 1 , the R 2 , and the R 3 (They cannot all become hydrogen atoms at the same time.) [Effects of the Invention]

[0009] According to this disclosure, it is possible to provide a cosmetic product that is non-sticky, blends well with the skin, and has a smooth feel. [Modes for carrying out the invention]

[0010] The embodiments of this disclosure will be described in detail below. However, the embodiments are not limited to the following description and can be modified as appropriate without departing from the gist of this disclosure. Furthermore, in this specification, the "~" indicating a numerical range means that the numbers before and after it are included as the lower and upper limits, respectively, unless otherwise specified.

[0011] (Cosmetics) The cosmetic according to one embodiment contains (A) 0.1% to 5% by mass of a glycine derivative represented by formula (1) or a salt thereof, (B) niacin or a derivative thereof, (C) a higher alcohol having 14 to 22 carbon atoms, (D) a hydrophilic polyoxyethylene alkyl ether, and (E) a glycerin monoalkyl ether. The cosmetic according to one embodiment may further contain other components as needed.

[0012] The present inventor has found that when niacin or a derivative thereof is blended into the oil-in-water emulsion composition described in Patent Document 1, the feeling of use such as stickiness and skin affinity deteriorates. On the other hand, by blending a specific amount of the glycine derivative represented by formula (1) or a salt thereof, it has been found that the feeling of use such as stickiness and skin affinity can be significantly improved, and the smoothness is excellent.

[0013] <(A) Glycine derivative represented by formula (1) or a salt thereof> The cosmetic according to one embodiment contains a glycine derivative represented by formula (1) or a salt thereof (hereinafter sometimes referred to as “component (A)”).

[0014]

Chem.

[0015] In the present disclosure, “each independently” means that R 1 and R 2However, this means that they may be the same or different.

[0016] In equation (1), R 1 and R 2 Preferably, one of them is a hydrogen atom and the other is an alkyl group, an aminomethylcarbonyl group, or an alkylcarbonyl group, R 1 and R 2 It is more preferable that one of them is a hydrogen atom and the other is an alkyl group having 1 to 3 carbon atoms, an aminomethyl carbonyl group, or an alkylcarbonyl group having 1 to 8 carbon atoms, R 1 and R 2 It is even more preferable that one of them is a hydrogen atom and the other is a methyl group, an aminomethyl carbonyl group, or a benzyl carbonyl group.

[0017] In equation (1), R 3 It is preferably a hydrogen atom or an alkyl group, more preferably a hydrogen atom or an alkyl group having 1 to 3 carbon atoms, and even more preferably a hydrogen atom or a methyl group.

[0018] (A) If component (A) is a salt of a glycine derivative represented by formula (1), there are no particular restrictions on the type of salt, as long as it is a pharmacologically acceptable salt, and it may be an inorganic salt or an organic salt. Examples of inorganic salts include hydrochloride, sulfate, phosphate, hydrobromide, sodium salt, potassium salt, magnesium salt, calcium salt, magnesium salt, and ammonium salt. Examples of organic salts include acetate, lactate, maleate, fumarate, tartrate, methanesulfonate, p-toluenesulfonate, triethanolamine salt, and amino acid salt.

[0019] Specific examples of component (A) include sarcosine (N-methylglycine), N-ethylglycine, N-propylglycine, N-diethylglycine, N-dimethylglycine, N-amidinoglycine, N-amidino-N-methylglycine, glycylglycine, phenacetulic acid, glycine methyl ester hydrochloride, glycine ethyl ester hydrochloride, glycine n-butyl ester hydrochloride, glycine t-butyl ester hydrochloride, glycine n-propyl ester hydrochloride, glycine n-pentyl ester hydrochloride, and glycine benzyl ester hydrochloride. These may be used individually or in combination of two or more. Among these, glycylglycine or a salt thereof is preferred as component (A). In formula (1), R 1 and R 2 Either one of them is a hydrogen atom, and the other is an aminomethylcarbonyl group, R 3 That is a hydrogen atom.

[0020] (A) Component may be synthesized using known methods or a commercially available product.

[0021] In a cosmetic composition according to one embodiment, the content of component (A) is 0.1% to 5% by mass, preferably 1% to 5% by mass, and more preferably 1% to 2% by mass, based on the total mass of the cosmetic composition. If the content of component (A) is less than 0.1% by mass, stickiness occurs, it does not blend well with the skin, and a smooth feeling is not obtained. Furthermore, even if component (A) is added in excess, a significant effect commensurate with the increase may not be obtained, so it is 5% by mass or less.

[0022] (B) Niacin or its derivatives A cosmetic composition according to one embodiment contains niacin or a derivative thereof (hereinafter sometimes referred to as "component (B)").

[0023] Niacin is a general term for niacin (nicotinic acid) and niacinamide (nicotinic acid amide). There are no particular restrictions on niacin derivatives, and they can be appropriately selected depending on the purpose. For example, nicotinic acid esters can be used. Examples of nicotinic acid esters include benzyl nicotinate, tocopherol nicotinate, methyl nicotinate, ethyl nicotinate, and β-butoxy nicotinate. These may be used individually or in combination of two or more. Among these, nicotinic acid amide is preferred as component (B).

[0024] Niacin is a water-soluble vitamin and is widely known as one of the B vitamins. Niacin can be obtained by extraction from natural materials such as rice bran using known methods, or by synthesis using known methods. For example, niacin listed in the 18th edition of the Japanese Pharmacopoeia can be used. Commercially available niacin can also be used.

[0025] Niacin derivatives can be obtained by synthesizing them from niacin obtained by the above method using known methods. Alternatively, commercially available niacin derivatives may be used.

[0026] In the cosmetic composition according to one embodiment, there is no particular limit to the lower limit of the content of component (B), and it can be appropriately selected according to the purpose, but it is preferably 2% by mass or more, and more preferably 3% by mass or more, relative to the total mass of the cosmetic composition. When the content of component (B) is 2% by mass or more, the non-stickiness, good absorption into the skin, and smoothness can be suitably improved. Similarly, in the cosmetic composition according to one embodiment, there is no particular limit to the upper limit of the content of component (B), and it can be appropriately selected according to the purpose, but even if it is added in excess, a remarkable effect commensurate with the increase may not be obtained, so it is preferably 10% by mass or more, and more preferably 8% by mass or more, relative to the total mass of the cosmetic composition. In the cosmetic composition according to one embodiment, the lower limit and upper limit of the content of component (B) can be appropriately combined, but it is preferably 2% by mass or more and 10% by mass or more, and more preferably 3% by mass or more and 8% by mass or more, relative to the total mass of the cosmetic composition.

[0027] <(C) Higher alcohols with 14-22 carbon atoms> A cosmetic composition according to one embodiment contains a higher alcohol having 14 to 22 carbon atoms (hereinafter sometimes referred to as "component (C)").

[0028] Component (C) is not particularly limited as long as it has 14 to 22 carbon atoms, and can be appropriately selected depending on the purpose, but from the viewpoint of gel formation, it is preferable to have a linear saturated alkyl chain.

[0029] (C) There are no particular restrictions on the number of carbon atoms in the alkyl chain of component (C), as long as it is between 14 and 22, and can be appropriately selected depending on the purpose, but 18 to 22 is preferred.

[0030] Specific examples of component (C) include myristyl alcohol, cetyl alcohol, stearyl alcohol, behenyl alcohol, and oleyl alcohol. These may be used individually or in combination of two or more. Among these, behenyl alcohol is preferred as component (C).

[0031] Component (C) may be synthesized by any known method as appropriate, or a commercially available product may be used. (C) Commercially available products containing this component include, for example, myristyl alcohol such as NCC-43 (manufactured by NOF Corporation), Conol 1495 (manufactured by Shin-Nippon Rika Co., Ltd.), and Hynol 14SS (manufactured by Kofu Alcohol Industry Co., Ltd.); cetyl alcohol such as NCC-44 (manufactured by NOF Corporation), Conol 1695 (manufactured by Shin-Nippon Rika Co., Ltd.), Cetanol, Hynol 16SS (manufactured by Kofu Alcohol Industry Co., Ltd.); stearyl alcohol such as NCC-45, NCC-46 (both manufactured by NOF Corporation), Conol 30F, Conol 30SS (both manufactured by Shin-Nippon Rika Co., Ltd.), Stearyl alcohol, Hynol 18SS (both manufactured by Kofu Alcohol Industry Co., Ltd.); behenyl alcohol such as Behenyl Alcohol (manufactured by Kofu Alcohol Industry Co., Ltd.), NCC-422 (manufactured by NOF Corporation), NIKKOL Behenyl Alcohol 65, and NIKKOL Behenyl Alcohol 80 (both manufactured by Nikko Chemicals Co., Ltd.); NOFCBLE Examples include oleyl alcohols such as CO-85S (manufactured by NOF Corporation), Oleyl Alcohol VP (manufactured by Higher Alcohol Industry Co., Ltd.), Rikakoll 85BJ, Rikakoll 90B, and Rikakoll 90BHR (all manufactured by Shin Nippon Rika Co., Ltd.).

[0032] There are no particular restrictions on the content of component (C) in the cosmetic composition according to one embodiment, and it can be appropriately selected depending on the purpose, but it is preferably 0.01% to 10% by mass, more preferably 0.01% to 5% by mass, and even more preferably 0.1% to 3% by mass, relative to the total mass of the cosmetic composition.

[0033] <(D) Hydrophilic polyoxyethylene alkyl ether> A cosmetic composition according to one embodiment contains a hydrophilic polyoxyethylene alkyl ether (hereinafter sometimes referred to as "component (D)"). Component (D) has a structure in which an alkyl chain and a polyoxyethylene chain are linked by an ether bond, and exhibits hydrophilicity.

[0034] There are no particular restrictions on the alkyl chain of component (D), and it can be appropriately selected depending on the purpose. It may be a linear alkyl chain or a branched alkyl chain. Furthermore, the alkyl chain of component (D) may be a saturated alkyl chain or an unsaturated alkyl chain. Among these, a linear saturated alkyl chain is preferred for component (D) from the viewpoint of gel formation.

[0035] In a cosmetic composition according to one embodiment, "hydrophilic" means that the HLB, which is determined by the relative strength of the hydrophilic group and the hydrophobic group, is greater than 10.

[0036] There are no particular restrictions on the number of carbon atoms in the alkyl chain of component (D), and it can be appropriately selected depending on the purpose, but 16 to 22 is preferred, and 18 to 22 is more preferred.

[0037] There are no particular restrictions on the average number of moles of ethylene oxide added to the polyoxyethylene chain in component (D), and it can be appropriately selected depending on the purpose, but 10 moles to 30 moles is preferred, and 15 moles to 25 moles is more preferred.

[0038] Specific examples of component (D) include Steareth-10, Steareth-11, Steareth-20, Steareth-30, Beheneth-10, Beheneth-20, and Beheneth-30. These may be used individually or in combination of two or more. Among these, Steareth-20 and Beheneth-20 are preferred, with Beheneth-20 being more preferred.

[0039] Component (D) may be synthesized by any known method as appropriate, or a commercially available product may be used. Examples of commercially available products of component (D) include polyoxyethylene stearyl ethers such as the EMALEX 600 series (manufactured by Nippon Emulsion Co., Ltd.) and the NIKKOL BS series (manufactured by Nikko Chemicals Co., Ltd.); and polyoxyethylene behenyl ethers such as the EMALEX BHA series (manufactured by Nippon Emulsion Co., Ltd.) and the NIKKOL BB series (manufactured by Nikko Chemicals Co., Ltd.).

[0040] There are no particular restrictions on the content of component (D) in the cosmetic composition according to one embodiment, and it can be appropriately selected depending on the purpose, but it is preferably 0.01% to 10% by mass, more preferably 0.01% to 5% by mass, and even more preferably 0.1% to 1% by mass, relative to the total mass of the cosmetic composition.

[0041] <(E) Glycerin monoalkyl ether> A cosmetic composition according to one embodiment contains glycerin monoalkyl ether (hereinafter sometimes referred to as "component (E)"). Component (E) has a structure in which an alkyl chain and glycerin are linked by an ether bond.

[0042] There are no particular restrictions on the alkyl chain of component (E), and it can be appropriately selected depending on the purpose. It may be a linear alkyl chain or a branched alkyl chain. Furthermore, the alkyl chain of component (E) may be a saturated alkyl chain or an unsaturated alkyl chain. Among these, a linear saturated alkyl chain is preferred for component (E) from the viewpoint of gel formation.

[0043] There are no particular restrictions on the number of carbon atoms in the alkyl chain of component (E), and it can be appropriately selected depending on the purpose, but 16 to 22 is preferred, and 16 to 18 is more preferred.

[0044] Specific examples of component (E) include glycerin monocetyl ether (chymyl alcohol) and glycerin monostearyl ether (batyl alcohol). These may be used individually or in combination of two or more. Among these, glycerin monostearyl ether is preferred.

[0045] Component (E) may be synthesized by any known method as appropriate, or a commercially available product may be used. Examples of commercially available products of component (E) include glycerin monocetyl ether such as NIKKOL Kimyl Alcohol 100 (manufactured by Nikko Chemicals Co., Ltd.); NIKKOL Batyl Alcohol 100, NIKKOL Batyl Alcohol EX (both manufactured by Nikko Chemicals Co., Ltd.).

[0046] There are no particular restrictions on the content of component (E) in the cosmetic composition according to one embodiment, and it can be appropriately selected depending on the purpose, but it is preferably 0.01% to 10% by mass, more preferably 0.01% to 5% by mass, and even more preferably 0.01% to 1% by mass, relative to the total mass of the cosmetic composition.

[0047] <<Mass ratio [(A+B) / (C+D+E)]>> The mass ratio of the total content of components (A) and (B) to the total content of components (C), (D), and (E) [(A+B) / (C+D+E)] is not particularly limited and can be appropriately selected depending on the purpose, but 1.7 to 4.5 is preferred, 1.8 to 3.0 is more preferred, and 2.0 to 3.0 is even more preferred. When the mass ratio [(A+B) / (C+D+E)] is 1.7 to 4.5, the product has good non-stickiness, blends well with the skin, and provides a smooth feeling.

[0048] <Other ingredients> A cosmetic composition according to one embodiment may contain other components other than components (A), (B), (C), (D), and (E).

[0049] Other components are not particularly limited as long as they do not impair the effect of the cosmetic composition according to one embodiment, and can be appropriately selected according to the purpose. Examples include components used in topical skin preparations such as cosmetics and pharmaceuticals. Specific examples of other components include whitening agents, moisturizers, antioxidants, oily components other than components (C) and (E), UV absorbers, surfactants other than component (D), thickeners, alcohols other than component (C), powder components, colorants, aqueous components other than components (A) and (B), solvents, chelating agents, pharmaceuticals, sugars, synthetic emulsions, amino acids, organic amines, preservatives, chelating agents, pH adjusters, various skin nutrients, etc. These may be used individually or in combination of two or more.

[0050] The content of other ingredients is not particularly limited as long as it does not impair the effect of the cosmetic composition according to one embodiment, and can be appropriately selected depending on the purpose.

[0051] <<Whitening agent>> There are no particular restrictions on the whitening agent, and they can be appropriately selected depending on the purpose. Examples include arbutin, 4-methoxysalicylic acid, tranexamic acid, alkoxysalicylic acid, glutathione, ethyl vitamin C, L-ascorbic acid, magnesium ascorbate phosphate, ascorbate glucoside, kojic acid, derivatives or salts thereof. These may be used individually or in combination of two or more.

[0052] L-ascorbic acid, commonly known as vitamin C, possesses strong reducing properties that promote cell respiration, enzyme activation, collagen formation, and melanin reduction. Examples of L-ascorbic acid derivatives include L-ascorbic acid monoesters such as L-ascorbic acid monophosphate and L-ascorbic acid 2-sulfate; L-ascorbic acid triesters such as L-ascorbic acid triphosphate; and L-ascorbic acid glucosides such as L-ascorbic acid 2-glucoside.

[0053] Examples of tranexamic acid derivatives include tranexamic acid dimers such as trans-4-(trans-aminomethylcyclohexanecarbonyl)aminomethylcyclohexanecarboxylic acid hydrochloride; esters of tranexamic acid and hydroquinone such as 4'-hydroxyphenyl ester of 4-(trans-aminomethylcyclohexanecarboxylic acid); esters of tranexamic acid and gentisic acid such as 2-(trans-4-aminomethylcyclohexylcarbonyloxy)-5-hydroxybenzoic acid; and amides of tranexamic acid such as trans-4-aminomethylcyclohexanecarboxylic acid methylamide, trans-4-(p-methoxybenzoyl)aminomethylcyclohexanecarboxylic acid, and trans-4-guanidinomethylcyclohexanecarboxylic acid.

[0054] Alkoxysalicylic acids are, for example, salicylic acid in which the hydrogen atoms at the 3rd, 4th, or 5th position are substituted with an alkoxy group. The alkoxy group substituent is preferably a methoxy group, ethoxy group, propoxy group, isopropoxy group, butoxy group, or isobutoxy group, with methoxy or ethoxy group being more preferred. Specific examples of alkoxysalicylic acids include 3-methoxysalicylic acid, 3-ethoxysalicylic acid, 4-methoxysalicylic acid, 4-ethoxysalicylic acid, 4-propoxysalicylic acid, 4-isopropoxysalicylic acid, 4-butoxysalicylic acid, 5-methoxysalicylic acid, 5-ethoxysalicylic acid, and 5-propoxysalicylic acid.

[0055] There are no particular restrictions on the type of salt used for the drug; examples include alkali metal salts or alkaline earth metal salts such as sodium salts, potassium salts, and calcium salts; ammonium salts; and amino acid salts.

[0056] <<Moisturizer>> Examples of humectants include cholesteryl-12-hydroxystearate, sodium lactate, dl-pyrrolidone carboxylate, urea, diglycerin ethylene oxide / propylene oxide adduct, chondroitin sulfate, and hyaluronic acid. In addition, alcohols other than component (C) described later can also be used as humectants. These may be used individually or in combination of two or more.

[0057] <<Antioxidant>> Examples of antioxidants include ascorbic acid, α-tocopherol, carotenoids, and sodium pyrosulfite. These may be used individually or in combination of two or more.

[0058] <<Oily components other than components (C) and (E)>> Examples of oily components other than components (C) and (E) include semi-solid oils, natural oils and fats, hydrocarbon oils and fats, synthetic oily components, and silicones. These may be used individually or in combination of two or more. Among these, it is preferable to include semi-solid oil.

[0059] -Semi-solid oil- Examples of semi-solid oils include petrolatum, hydrogenated palm oil, palm kernel oil, macadamia nut oil phytosteryl, tetra(behenic acid / benzoic acid / ethylhexanoic acid) pentaerythritol, and bis-diglyceryl polyacyladipate-2. These may be used individually or in combination of two or more.

[0060] There are no particular restrictions on the content of semi-solid oil in the cosmetic composition according to one embodiment, and it can be appropriately selected depending on the purpose, but 0.1% to 5% by mass is preferred.

[0061] Furthermore, it is preferable to adjust the content of semi-solid oil in the cosmetic composition according to one embodiment so that it is in the range of 1% to 50% by mass relative to the total amount of liquid oil.

[0062] -Natural oils and fats- Examples of natural oils and fats include camellia oil, macadamia nut oil, olive oil, castor oil, safflower oil, soybean oil, tea seed oil, cocoa butter, coconut oil, hydrogenated coconut oil, palm oil, Japanese wax, hydrogenated castor oil, beeswax, candelilla wax, carnauba wax, lanolin, liquid lanolin, jojoba wax, hard lanolin, polyoxyethylene lanolin alcohol ether, and polyoxyethylene cholesterol ether. These may be used individually or in combination of two or more.

[0063] -Hydroxide-based oils and fats- Examples of hydrocarbon oils and fats include liquid paraffin, ozokerite, squalene, paraffin, ceresin, petrolatum, microcrystalline wax, and hydrogenated polydecene. These may be used individually or in combination of two or more.

[0064] -Synthetic oil components- Examples of synthetic oily components include isopropyl myristate, octyldodecyl myristate, isopropyl palmitate, cholesteryl 12-hydroxystearate, ethylene glycol di-2-ethylhexylate, dipentaerythritol fatty acid ester, pentaerythritol tetra-2-ethylhexylate, glycerin tri-2-ethylhexylate, trimethylolpropane triisostearate, cetyl-2-ethylhexanoate, castor oil fatty acid methyl ester, pentaerythrityl tetraethylhexanoate, cetyl ethylhexanoate, triethylhexanoin, and caprylic / capric triglyceride. These may be used individually or in combination of two or more.

[0065] -Silicones- Examples of silicones include linear polysiloxanes such as dimethylpolysiloxane (dimethicone), methylphenylpolysiloxane, and methylhydrogenpolysiloxane; cyclic polysiloxanes such as decamethylpolysiloxane, dodecamethylpolysiloxane, and tetramethyltetrahydrogenpolysiloxane; silicone resins capable of forming a three-dimensional network structure; and silicone rubber. These may be used individually or in combination of two or more types.

[0066] In the cosmetic composition according to one embodiment, there are no particular restrictions on the content of oily components, and they can be appropriately selected depending on the purpose, but the liquid oil content is preferably 1% to 30% by mass, and more preferably 1% to 10% by mass.

[0067] <<UV absorber>> Examples of UV absorbers include benzoic acid-based UV absorbers such as para-aminobenzoic acid, para-aminobenzoic acid monoglycerol ester, N,N-dipropoxypara-aminobenzoate ethyl ester, and N,N-dimethylpara-aminobenzoate ethyl ester; anthranilic acid-based UV absorbers such as homomenthyl-N-acetylanthranilate; and amyl salicylate, homomenthyl salicylate, octyl salicylate, phenyl salicylate, benzyl salicylate, and p-isopropanolphenyl salicylate. Salicylic acid-based UV absorbers such as: octyl cinnamate, ethyl-4-isopropyl cinnamate, methyl-2,5-diisopropyl cinnamate, ethyl-2,4-diisopropyl cinnamate, propyl-p-methoxy cinnamate, isoamyl-p-methoxy cinnamate, octyl-p-methoxy cinnamate (2-ethylhexyl-p-methoxy cinnamate), 2-ethoxyethyl-p-methoxy cinnamate, 2-ethylhexyl-α-cyano-β-phenyl cinnamate, glyceryl Cinnamic acid-based UV absorbers such as mono-2-ethylhexanoyl-di-p-methoxycinnamate; benzophenone-based UV absorbers such as 2,4-dihydroxybenzophenone, 2,2'-dihydroxy-4-methoxybenzophenone, 2,2',4,4'-tetrahydroxybenzophenone, 2-hydroxy-4-methoxybenzophenone, 2-hydroxy-4-methoxybenzophenone-5-sulfonate, 4-phenylbenzophenone, and 2-ethylhexyl-4'-phenylbenzophenone-2-carboxylate. Examples of external radiation absorbers include 3-(4'-methylbenzylidene)-d,l-camphor, 3-benzylidene-d,l-camphor, urocanic acid, ethyl urocanic acid, 2,2'-hydroxy-5-methylphenylbenzotriazole, 2-(2'-hydroxy-5'-t-octylphenyl)benzotriazole, dibenzarazine, dianisioylmethane, 4-methoxy-4'-t-butyldibenzoylmethane, and 5-(3,3-dimethyl-2-norbornylidene)-3-pentan-2-one. These may be used individually or in combination of two or more.

[0068] <<Surfactants other than component (D)>> Examples of surfactants other than component (D) include lipophilic nonionic surfactants, anionic surfactants, cationic surfactants, and amphoteric surfactants. These may be used individually or in combination of two or more types.

[0069] -Lipophilic nonionic surfactant- Examples of lipophilic nonionic surfactants include sorbitan fatty acid esters such as sorbitan monooleate, sorbitan monoisostearate, sorbitan monolaurate, sorbitan monopalmitate, sorbitan monostearate, sorbitan sesquioleate, and sorbitan penta-2-ethylhexyl diglycerol; glycerin or polyglycerin esters such as glycerin monostearate, glycerin pyroglutamate α,α'-oleate, and glycerin monostearate malate; propylene glycol fatty acid esters such as propylene glycol monostearate; and hydrogenated castor oil derivatives.

[0070] -Anionic surfactant- Examples of anionic surfactants include fatty acid soaps such as sodium laurate and sodium palmitate; higher alkyl sulfate salts such as sodium lauryl sulfate and potassium lauryl sulfate; alkyl ether sulfate salts such as polyoxyethylene lauryl sulfate triethanolamine and polyoxyethylene lauryl sulfate sodium; N-acyl sarcosinates such as sodium lauroyl sarcosinate; higher fatty acid amide sulfonates such as sodium N-myristoyl-N-methyl taurate, sodium coconut oil fatty acid methyl taulide, and sodium lauryl methyl taulide; phosphate salts such as sodium polyoxyethylene oleyl ether phosphate and sodium polyoxyethylene stearyl ether phosphate; sodium di-2-ethylhexyl sulfosuccinate, monolauroyl monoethanolamide, sodium polyoxyethylene sulfosuccinate, and Examples include sulfosuccinates such as sodium uryl polypropylene glycol sulfosuccinate; alkylbenzene sulfonates such as sodium linear dodecylbenzenesulfonate and linear dodecylbenzenesulfonate triethanolamine; N-acyl glutamates such as monosodium N-lauroyl glutamate and disodium N-stearoyl glutamate; higher fatty acid ester sulfates such as sodium hydrogenated coconut oil fatty acid glycerin sulfate; polyoxyethylene alkyl ether carboxylates; α-olefin sulfonates; higher fatty acid ester sulfonates; secondary alcohol sulfates; higher fatty acid alkylolamide sulfates; sodium lauroyl monoethanolamide succinate; N-palmitoyl aspartic acid; ditriethanolamine; hydrolyzed alkali salts of coconut oil fatty acid collagen; and stearoyl methyl taurate.

[0071] - Cationic surfactants - Examples of cationic surfactants include alkyltrimethylammonium salts such as stearyltrimethylammonium chloride and lauryltrimethylammonium chloride; dialkyldimethylammonium salts such as distearyldimethylammonium chloride; alkylpyridinium salts such as poly(N,N'-dimethyl-3,5,-methylenepiperidinium) chloride and cetylpyridinium chloride; alkylquaternary ammonium salts and alkyldimethylbenzylammonium salts; alkylisoquinolinium salts; dialkylmolyphonium salts; polyoxyethylene alkylamines; alkylamine salts; polyamine fatty acid derivatives; amyl alcohol fatty acid derivatives; benzalkonium chloride; benzethonium chloride; cationic polymers; and β-NN-dimethyl-N-ethylammonium ethyl vinylpyrrolidone chloride copolymer.

[0072] - Amphoteric surfactants - Examples of amphoteric surfactants include imidazoline-based amphoteric surfactants such as 2-undecyl-N,N,N,-(hydroxyethylcarboxymethyl)-2-imidazoline sodium and 2-cocoyl-2-imidazolinium hydroxide-1-carboxyethyloxy disodium salt; and betaine-based amphoteric surfactants such as 2-heptadecyl-N-carboxymethyl-N-hydroxyethylimidazolinium betaine, lauryldimethylaminoacetic acid betaine, alkyl betaine, amide betaine, and sulfobetaine.

[0073] <<Thickening agent>> Examples of thickening agents include gum arabic, carrageenan, tragacanth gum, quince seed (marmelo), casein, sodium caseinate, dextrin, gelatin, sodium alginate, methylcellulose, ethylcellulose, carboxymethylcellulose, hydroxyethylcellulose, hydroxypropylcellulose, polyvinyl alcohol, sodium polyacrylate, carboxyvinyl polymer (carbomer), guar gum, xanthan gum, magnesium aluminum silicate, bentonite, and hectorite. These may be used individually or in combination of two or more.

[0074] <<(C) Alcohols other than ingredient>> Examples of alcohols other than component (C) include polyhydric alcohols such as ethylene glycol, propylene glycol, dipropylene glycol (DPG), 1,3-butylene glycol (BG), glycerin, erythritol, trimethylolpropane, pentaerythritol, sorbitol, maltitol, diglycerin, and polyethylene glycol.

[0075] <<Powdered ingredients>> The powdered components may be inorganic or organic. These may be used individually or in combination of two or more.

[0076] Examples of inorganic powder components include mica, talc, kaolin, mica, sericite, muscovite, phlogopite, synthetic mica, rose mica, biotite, thiamite, synthetic mica, anhydrous silicic acid (silica), magnesium carbonate, calcium carbonate, aluminum silicate, barium silicate, calcium silicate, magnesium silicate, strontium silicate, silica, calcined calcium sulfate (calcined gypsum), aluminum oxide, barium sulfate, zeolite, calcium phosphate, fluorapatite, hydroxyapatite, ceramic powder, titanium dioxide, zinc oxide, metal soaps (zinc myristate, calcium palmitate, aluminum stearate, etc.), and boron nitride.

[0077] Examples of organic powders include polyamide resin powder (nylon powder), polyethylene powder, polymethyl methacrylate powder, polystyrene powder, calcium carbonate powder, magnesium carbonate powder, styrene-acrylic acid copolymer resin powder, polymethylsesquioxane powder, and cellulose powder.

[0078] <<Colorants>> Examples of colorants include pigments and dyes.

[0079] -Pigment- Examples of pigments include inorganic pigments, organic pigments, pearl pigments, and metal powder pigments.

[0080] Examples of inorganic pigments include titanium dioxide, zinc oxide, iron oxide (red iron oxide), iron titanate, yellow iron oxide, black iron oxide, carbon black, lower titanium oxide, mango violet, cobalt violet, chromium oxide, ultramarine, and Prussian blue.

[0081] Examples of organic pigments include Red No. 3, Red No. 104, Red No. 106, Red No. 201, Red No. 202, Red No. 204, Red No. 205, Red No. 220, Red No. 226, Red No. 227, Red No. 228, Red No. 230, Red No. 401, Red No. 405, Red No. 505, Orange No. 203, Orange No. 204, Orange No. 205, Yellow No. 4, Yellow No. 5, Yellow No. 202, Yellow No. 203, Yellow No. 205, Yellow No. 401, Blue No. 1, Blue No. 404, Green No. 3, and their zirconium lake, barium lake, or aluminum lake forms.

[0082] Examples of pearl pigments include titanium dioxide-coated mica, colored titanium dioxide-coated mica, titanium dioxide-coated bismuth oxychloride, bismuth oxychloride, and fish scale foil.

[0083] Examples of metal powder pigments include aluminum powder and copper powder.

[0084] -Dye- Examples of pigments include natural pigments such as chlorophyll and beta-carotene.

[0085] <<Solvent>> Examples of solvents include water and lower alcohols. Examples of lower alcohols include alcohols with 5 or fewer carbon atoms. Specific examples of lower alcohols include methanol, ethanol, propyl alcohol, isopropyl alcohol, 2-amino-2-methyl-1-propanol, and 2-amino-2-methyl-1,3-propanediol.

[0086] <<Metal sequestering agent>> Examples of chelating agents include disodium edetate, trisodium edetate, sodium citrate, sodium polyphosphate, sodium metaphosphate, and gluconic acid.

[0087] <<Medications>> Examples of drugs include caffeine, tannins, verapamil, licorice extract, glabridin, hot water extract of the fruit of Pyracantha, various herbal medicines, tocopherol acetate, glycyrrhizic acid, derivatives thereof, or salts thereof.

[0088] <<Sugars>> Examples of sugars include glucose, fructose, mannose, sucrose, and trehalose.

[0089] <<Synthetic resin emulsion>> Examples of synthetic resin emulsions include acrylic resin emulsions and polyvinyl acetate resin emulsions.

[0090] <<Amino Acids>> Examples of amino acids include glycine, leucine, phenylalanine, tyrosine, aspartic acid, glutamic acid, sodium glutamate, arginine, histidine, lysine, cystine, cysteine, sodium acyl sarcosinate (sodium lauroyl sarcosinate), acyl glutamate, glutathione, and pyrrolidone carboxylic acid.

[0091] <<Organic amines>> Examples of organic amines include monoethanolamine, diethanolamine, triethanolamine, morpholine, triisopropanolamine, 2-amino-2-methyl-1,3-propanediol, and 2-amino-2-methyl-1-propanol.

[0092] <<Preservatives>> Examples of preservatives include benzoic acid, salicylic acid, paraoxybenzoic acid esters (such as methyl paraben, ethyl paraben, butyl paraben, etc.), sorbic acid, parachlorometacresol, hexachlorophene, benzalkonium chloride, chlorhexidine chloride, trichlorocarbanilide, photosensitizer, phenoxyethanol, and the like.

[0093] <<Chelating agent>> Examples of chelating agents include citramalic acid, agaric acid, glyceric acid, shikimic acid, hinokitiol, gallic acid, tannic acid, caffeic acid, trisodium ethylenediamine-N,N,N',N'-tetraacetate dihydrate (EDTA-2Na·2H2O), ethylene glycol diamine tetraacetic acid, diethylenetriamine pentaacetic acid, phytic acid, polyphosphoric acid, metaphosphoric acid, their analogs, their alkali metal salts, their carboxylic acid esters, and the like.

[0094] <<pH adjuster>> Examples of pH adjusters include acid agents such as lactic acid, citric acid, glycolic acid, succinic acid, tartaric acid, malic acid, etc.; and alkali agents such as sodium hydrogen carbonate, ammonium hydrogen carbonate, etc.

[0095] [Dosage form] The dosage form of the cosmetic according to one embodiment is not particularly limited and can be appropriately selected according to the purpose, but it is preferably a liquid cosmetic, more preferably a liquid emulsified cosmetic, and even more preferably an oil-in-water emulsified cosmetic.

[0096] There are no particular restrictions on the product form of the cosmetic composition according to one embodiment, and it can be appropriately selected according to the purpose. Examples include skincare cosmetics such as lotions, creams, emulsions, and serums; makeup cosmetics such as foundations and makeup bases; sunscreen cosmetics; suntan cosmetics; skin cleansing cosmetics such as facial cleansers and makeup removers; and ointments. Furthermore, the product form of the cosmetic composition according to one embodiment may be in the form of impregnating a base material such as a pack. Among these, the product form of the cosmetic composition according to one embodiment is preferably an emulsion because it is not sticky and has excellent skin compatibility and smoothness.

[0097] [viscosity] The viscosity of the cosmetic composition according to one embodiment at 30°C is not particularly limited and can be appropriately selected depending on the purpose. However, when it is a liquid cosmetic composition, a viscosity of 0 mPa·s to 15,000 mPa·s is preferred, and 1,500 mPa·s to 10,000 mPa·s is more preferred. The viscosity of the cosmetic composition according to one embodiment can be measured, for example, using a B-type viscometer at 30°C under the conditions of rotor No. 3, rotation speed of 12 rpm, and for 1 minute.

[0098] [pH] There are no particular restrictions on the pH of the cosmetic composition according to one embodiment, and it can be appropriately selected depending on the purpose, but from the viewpoint of application to the skin, 5 to 8 is preferred.

[0099] [Manufacturing method] There are no particular limitations on the method for producing a cosmetic composition according to one embodiment, and it can preferably be produced according to a method commonly used for liquid cosmetics, and more preferably for oil-in-water emulsion cosmetics. For example, one method involves heating and dissolving an aqueous component and mixing it uniformly, then adding an oily component that has been similarly heated, dissolved, and mixed uniformly, and mixing to emulsify it.

[0100] There are no particular restrictions on the heating temperature of the aqueous and oil phase components, and they can be appropriately selected depending on the purpose, but 70°C to 80°C is preferred.

[0101] There are no particular restrictions on the emulsification method, and known methods can be used. Examples include mechanical emulsification using high-pressure emulsifiers such as high-pressure homogenizers, high-shear dispersers, and colloid mills; phase inversion emulsification; coagulation; liquid crystal emulsification; and D-phase emulsification. These methods can be used individually or in combination.

[0102] A specific example of a method for producing a cosmetic composition according to one embodiment is as follows: First, an aqueous phase is prepared by dissolving components (A) and (B), and optionally other components appropriately selected from among water-soluble components, in water. Next, an oil phase is prepared by mixing components (C), (D), and (E), and optionally other components appropriately selected from among water-insoluble components. Finally, the oil phase is added to the aqueous phase and stirred to produce a cosmetic composition according to one embodiment. [Examples]

[0103] The embodiments will be described in more detail below with reference to examples and comparative examples, but the embodiments are not limited to these examples and comparative examples. In the examples and comparative examples, the content of each component shown in Table 1 is expressed as "mass %" relative to the total mass of the oil-in-water emulsion cosmetic, and all values ​​are converted to pure content unless otherwise specified. The mass ratio [(A+B) / (C+D+E)] is rounded to two decimal places.

[0104] (Examples 1-3 and Comparative Examples 1-2) Oil-in-water emulsion cosmetics (lotions) with the compositions and content (mass%) shown in Table 1 were prepared by conventional methods. For each of the oil-in-water emulsion cosmetics in Examples 1-3 and Comparative Examples 1-2, the particle size of the dispersed oil droplets was measured using a microscope, and it was confirmed that particles of 10 μm or less were dispersed.

[0105] <Rating> The oil-in-water emulsion cosmetic compositions prepared in Examples 1-3 and Comparative Examples 1-2 were evaluated for "non-stickiness," "good absorption," and "smoothness" using the following method. The evaluation results are shown in Table 1.

[0106] <<Evaluation of non-stickiness>> The non-greasy feel of each oil-in-water emulsion cosmetic composition in Examples 1-3 and Comparative Examples 1-2 was evaluated using the following method. Five expert evaluators confirmed the non-greasy feel of each oil-in-water emulsion cosmetic composition in Examples 1-3 and Comparative Examples 1-2 when applied to the skin, and evaluated them based on the evaluation criteria below. [Evaluation criteria for non-stickiness] A (Excellent): 5 out of 5 people reported no stickiness. B (Good): 4 out of 5 people reported that it was not sticky. C (Fair): 3 out of 5 people reported no stickiness. D (Poor): Two or fewer out of five people reported that it was not sticky.

[0107] <<Evaluation of ease of use>> The skin-friendly properties of each oil-in-water emulsion cosmetic composition in Examples 1-3 and Comparative Examples 1-2 were evaluated using the following method. Five expert evaluators confirmed the skin-friendly properties of each oil-in-water emulsion cosmetic composition in Examples 1-3 and Comparative Examples 1-2 when applied to the skin, and evaluated them based on the evaluation criteria below. [Evaluation criteria for ease of use] A (Very Good): 5 out of 5 people responded that it was easy to get used to. B (Good): 4 out of 5 people responded that they found it easy to get used to. C (Fairly Good): 3 out of 5 people responded that it was easy to get used to. D (Poor): Two or fewer out of five people answered that they found it easy to get used to.

[0108] <<Evaluation of smoothness>> The smoothness of each oil-in-water emulsion cosmetic composition in Examples 1-3 and Comparative Examples 1-2 was evaluated using the following method. Five expert evaluators confirmed the smoothness of each oil-in-water emulsion cosmetic composition in Examples 1-3 and Comparative Examples 1-2 when applied to the skin, and evaluated them based on the evaluation criteria below. [Criteria for evaluating smoothness] A (Very Good): 5 out of 5 people reported a smooth feeling. B (Good): 4 out of 5 people reported a smooth feeling. C (Fairly Good): 3 out of 5 people reported a smooth feeling. D (Poor): Two or fewer out of five people reported a smooth feeling.

[0109] [Table 1]

[0110] Examples of the types of disclosures include the following: <1> (A) A glycine derivative represented by formula (1) or a salt thereof in an amount of 0.1% to 5% by mass,

[0111] [ka] (In the formula, R 1 and R 2 Each of these independently represents a hydrogen atom, an alkyl group, an alkenyl group, an aryl group, an aralkyl group, an aminomethylcarbonyl group, an amidino group, an alkylcarbonyl group, an alkenylcarbonyl group, an arylcarbonyl group, or an aralkylcarbonyl group, and R 3 R represents a hydrogen atom, an alkyl group, an alkenyl group, an aryl group, or an aralkyl group. However, the R 1 , the R 2 , and the R 3 (They cannot all become hydrogen atoms at the same time.) (B) Niacin or its derivatives, (C) Higher alcohols with 14 to 22 carbon atoms, (D) Hydrophilic polyoxyethylene alkyl ether, (E) Glycerin monoalkyl ether, It is a cosmetic product containing [a specific ingredient]. <2> The above (A) component is glycylglycine or a salt thereof. <1> It is a cosmetic product as described above. <3> The content of component (A) is 1% by mass to 2% by mass, <1> or <2> It is a cosmetic product as described above. <4> The above (C) higher alcohol having 14 to 22 carbon atoms has a linear saturated alkyl chain, <1> from <3> It is a cosmetic product as described in any of the following. <5> The alkyl chain of the hydrophilic polyoxyethylene alkyl ether (D) is a linear saturated alkyl chain, <1> from <4> It is a cosmetic product as described in any of the following. <6> The average number of moles of ethylene oxide added to the polyoxyethylene chain of the hydrophilic polyoxyethylene alkyl ether (D) is 10 to 30. <1> from <5> It is a cosmetic product as described in any of the following. <7> The alkyl chain of the (E) glycerin monoalkyl ether is a linear saturated alkyl chain, <1> from <6> It is a cosmetic product as described in any of the following. <8> The above (E) component is glycerin monostearyl ether, <1> from <7> It is a cosmetic product as described in any of the following. <9> The mass ratio of the total content of component (A) and component (B) to the total content of component (C), component (D), and component (E) [(A+B) / (C+D+E)] is 1.7 to 4.5. <1> from <8> It is a cosmetic product as described in any of the following.

[0112] As described above, this disclosure has been explained based on specific embodiments and examples, but these embodiments and examples are merely presented as examples, and this disclosure is not limited to the above embodiments and examples. The above embodiments can be implemented in various other forms, and various combinations, omissions, substitutions, additions, modifications, etc., are possible without departing from the spirit of the invention. These embodiments and their variations are included in the scope and spirit of the invention, as well as in the claims of the invention and its equivalents.

Claims

1. (A) A glycine derivative represented by formula (1) or a salt thereof in an amount of 0.1% to 5% by mass, 【Chemistry 1】 (In the formula, R １ and R ２ Each of these independently represents a hydrogen atom, an alkyl group, an alkenyl group, an aryl group, an aralkyl group, an aminomethylcarbonyl group, an amidino group, an alkylcarbonyl group, an alkenylcarbonyl group, an arylcarbonyl group, or an aralkylcarbonyl group, R ３ R represents a hydrogen atom, an alkyl group, an alkenyl group, an aryl group, or an aralkyl group. However, the R １ , the R ２ , and the R ３ (They cannot all become hydrogen atoms at the same time.) (B) Niacin or its derivatives, (C) Higher alcohols with 14 to 22 carbon atoms, (D) Hydrophilic polyoxyethylene alkyl ether and (E) Glycerin monoalkyl ether and Cosmetics containing [a specific ingredient].

2. The cosmetic composition according to claim 1, wherein component (A) is glycylglycine or a salt thereof.

3. The cosmetic composition according to claim 1 or 2, wherein the content of component (A) is 1% by mass to 2% by mass.

4. The cosmetic composition according to claim 1 or 2, wherein the (C) higher alcohol having 14 to 22 carbon atoms has a linear saturated alkyl chain.

5. The cosmetic composition according to claim 1 or 2, wherein the alkyl chain of the hydrophilic polyoxyethylene alkyl ether (D) is a linear saturated alkyl chain.

6. The cosmetic composition according to claim 1 or 2, wherein the average number of moles of ethylene oxide added to the polyoxyethylene chain of the hydrophilic polyoxyethylene alkyl ether (D) is 10 to 30.

7. The cosmetic composition according to claim 1 or 2, wherein the alkyl chain of the (E) glycerin monoalkyl ether is a linear saturated alkyl chain.

8. The cosmetic composition according to claim 1 or 2, wherein the (E) component is glycerin monostearyl ether.

9. The cosmetic composition according to claim 1 or 2, wherein the mass ratio of the total content of component (A) and component (B) to the total content of component (C), component (D), and component (E) [(A + B) / (C + D + E)] is 1.7 to 4.5.

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