Accessories for injection devices, including a pivotable cover.

Abstract

To provide an accessory that enables easier operation of the needle safety device. [Solution] An accessory 200 for an injection device having a needle cap, the accessory 200 comprises a main body portion 202 having a recess 220 adapted to receive the injection device, and a cover 204 connected to the main body portion 202. The cover 204 is pivotable between an open position in which the recess 220 is exposed and the injection device is received, and a closed position in which the cover 204 at least partially closes the recess and holds the injection device to the main body portion 202. The accessory 200 further comprises a cap removal device having a gripping portion adapted to hold the needle cap. The cap removal device is movable relative to the main body portion 202.

Description

Technical Field

[0001] The present disclosure relates to accessories for an injection device.

Background Art

[0002] Needle safety devices are commonly used in combination with syringes when performing injections to reduce the risk of accidental needle sticks that could result in transmission of blood - borne pathogens. These needle safety devices are typically required to protect healthcare providers (HCPs), such as nurses, who often use syringes to inject patients. These needle safety devices can generally be classified as one of two types: (1) passive devices that automatically cover the needle after injection without requiring additional steps from the user to move the device, and (2) devices that require additional steps by the user to move the needle safety feature.

[0003] For various reasons, users may fail to perform the additional actions required to operate non - passive devices, so needle safety devices are generally considered to be superior in terms of their ability to protect users from accidental needle sticks. Healthcare institutions and healthcare systems often require the use of needle safety devices in situations where HCPs perform injections. Furthermore, it is desirable for needle safety devices to reduce the risk of injury, infection, and spread of blood - borne pathogens to patients, family members, caregivers, and any person who may come into contact with the injection device during the process of injection and when disposing of the used syringe.

[0004] A commonly used example of a needle safety device is by Becton Dickinson. It is a device manufactured under the UltraSafe® family. fe (trademark) consists of two plastic components and a specially designed plunger rod. It consists of a spring that is assembled into the syringe. Once the injection is complete, the plunger rod Engage with the latch on the UltraSafe® housing component, move the device, This extends one of the housing components on the needle and locks it in place, locking out Set to the T position. An example of the UltraSafe (trademark) device is shown in Figures 1A and 1B.

[0005] Figure 1A shows the device in its ready-to-use state, i.e., in the pre-injection position, before the injection is administered. Figure 1B shows the device in a safe, used state, i.e., the lockout position, after the injection is complete. The device is shown.

[0006] Figures 2A, 2B, 2C, and 2D show the use of an UltraSafe® device. Typical instructions are shown below. Use UltraSafe® as shown in these instructions. The process for doing so is essentially the same as that for administering an injection using an exposed syringe. Yes. Pinching the skin and injecting at a 45-degree angle is essential to limit the depth of the injection. Therefore, the injection is administered subcutaneously and not intramuscularly (too deep) or intradermally (into the skin). Ensure that the injection is delivered correctly. Injections that are too shallow or too deep can cause problems for drugs intended for subcutaneous injection. It may affect the pharmacokinetics (PK) and pharmacodynamics (PD).

[0007] As shown in Figures 2A to 2D, to achieve subcutaneous injection, the syringe must be used appropriately. The injection process is complex, and the procedure varies from user to user, which can lead to differences in injection depth and drug administration. This can affect the efficacy of the injection. Health care professionals such as nurses should be aware of the importance of using syringes in injection procedures. They are proficient and have received this training. However, techniques vary from nurse to nurse, and this is the case. It can affect PK and PD. Furthermore, typical injection techniques require the use of both hands. The nurse holds the syringe with one hand and administers the injection with the other, but this can cause problems for children who may move during the injection. It becomes difficult to administer injections to any difficult patient. Furthermore, nurses have difficulty using syringes. Even when there are no problems, patients are often afraid of syringes and needles, and injections can be a source of anxiety for patients. It often results in an unpleasant experience.

[0008] It is particularly difficult for patients and caregivers to use syringes such as UltraSafe™. It is difficult. This is because the usage process is not only complicated, but the syringe with the exposed needle is This is because it tends to cause anxiety in patients. [Overview of the Initiative] [Problems that the invention aims to solve]

[0009] Therefore, it enables easier operation of needle safety devices, such as UltraSafe™. We need to develop accessories to enable this functionality. [Means for solving the problem]

[0010] In one aspect of the present invention, an accessory for an injection device having a needle cap is provided, the accessory is , a main body portion having a recess adapted for receiving an injection device, and connected to the main body portion A cover, the cover having an open position where a recess is exposed to receive an injection device, and the cover having a recess A cover that can be pivoted between an open position and a closed position where the cover at least partially closes a portion to hold the injection device in the body portion and a cap removal device having a gripping portion adapted to hold a needle cap, the cap removal device being movable relative to the body portion where the cap removal device is provided with a cap removal device, and the cover is moved by the user and has a proximal end adapted to move the cover from the open position to the closed position and a distal end adapted to move the gripping portion towards the end of the accessory to at least partially remove the needle cap from the injection device when the cover is moved from the open position to the closed position In this way, the needle cap can be automatically removed when the cover is closed This is achieved by a cover that functions as a lever to move the cap removal device and remove the needle cap This provides a simple and reliable mechanism for removing the needle cap in a way that is easy for users who are not very dexterous

[0011] Moreover, the cover provides a mechanical advantage for moving the cap removal device to reduce the amount of force required by the user

[0012] In another aspect of the present invention, an accessory for an injection device having a needle cap is provided, the accessory having a body portion with a recess adapted to receive the injection device and a cover connected to the body portion, the cover being pivotable between an open position where the recess is exposed to receive the injection device and a closed position where the cover at least partially closes the recess to hold the injection device in the body portion and a cap removal device having a gripping portion where the cap removal device is movable relative to the body portion ​​​​​​The device has an extended configuration that allows the needle cap to pass between the gripping parts, and the gripping parts are the needle cap It has a shrinkage configuration that holds the needle cap and removes it at least partially from the injection device. The cover and cap removal device are equipped with a cap removal device, and the cover and cap removal device are equipped with a cap removal device, and the cover is open When moved from the position towards the closed position, the cap removal device changes from an extended configuration to a retracted configuration. They are connected to each other in a way that allows them to transition to the next state.

[0013] In this way, the injection device can be loaded into the accessory without the gripping part interfering with the needle cap. It is possible. Next, when the cover is closed, the gripping part automatically removes the needle cap. It closes on the needle cap. Also, after the cover is removed, the gripping part is opened again. Release the cover so that it can be separated from the accessories.

[0014] In another aspect of the present invention, a safety shield and a mechanism that allows the user to grasp the injection device At least one flange adapted to the above, and at least one flange An injection device having a syringe sheath that is movable from the pre-inlet position to the lockout position. Accessories are provided, and the accessories have recesses that are fitted to receive the safety shield of the injection device. , comprising a slot adapted to receive at least one flange of an injection device, A main body and a cover connected to the main body, the recess and slot exposed for injection The device has open positions for receiving the safety shield and flange, respectively, and recesses and slots are provided to reduce the number of openings. Even if not, it is pivotable between a closed position that partially closes and holds the injection device in the main body, and A cover and a slot comprising at least one flange distal to the main body portion It resists movement in the direction and proximal direction, and locks the syringe sheath from the pre-injection position. It is molded to allow movement in the proximal direction relative to the main body towards the "out" position.

[0015] In this way, the cover opens so that the recesses and slots can be more easily accessed. It can be released. Then, when the cover is closed, the slot holds the flange in place. However, the syringe sheath is movable and therefore does not interfere with the function of the injection device. .

[0016] In another aspect of the present invention, an accessory for an injection device having a needle cap is provided, and this accessory It comprises a main body portion having a recess adapted for receiving an injection device, and connected to the main body portion The cover has an open position in which a recess is exposed to receive the injection device, and the cover is A closed position that holds the injection device to the main body by at least partially closing the recess, and a pivot between these two positions. A cap comprising a movable cover and a gripping portion adapted to hold the needle cap. A removal device, the cap removal device removes the needle cap from the injection device. Therefore, the cap is removable, which is movable axially relative to the main body from the initial position to the forward position. The device includes a track, and the main body is equipped with a cap removal device, and the cap removal device is equipped with a track, and the main body is equipped with a track. The track is positioned inside to move axially, and the injector is located in the main body. When doing so, the cap removal device is held against the track by the syringe. It conforms to the requirements.

[0017] In this way, the injection device has the function of holding the needle cap removal device inside the track. This will eliminate the need for additional components and simplify the design and manufacturing process.

[0018] The needle cap (often also called the "needle boot" or "needle shield") is rigid. It may be a needle cap or a non-rigid needle cap. A rigid needle cap has at least two components It may be formed of constituent elements, for example, a rigid outer shell and a syringe when in a given position It may include an inner body surrounding the upper needle. The inner body may be a flexible inner body, an elastic inner body , or it may be a flexible inner body. This inner body may be a rubber inner body. Alternatively, a non-rigid needle cap may be used, in which case the needle cap is a single flexible The body may be a rigid body, an elastic body, or a flexible body, for example, a rubberized needle boot. [Brief explanation of the drawing]

[0019] Embodiments of the present invention will be described simply by reference to the following drawings. [Figure 1A] This is a perspective view of an injection device in a ready-to-use state before use. [Figure 1B] A perspective view of an injection device in a secure lockout state. [Figure 2A] Figure 1 is an example of a side view showing a typical use of the injection device. [Figure 2B] Figure 1 is an example of a side view showing a typical use of the injection device. [Figure 2C] Figure 1 is an example of a side view showing a typical use of the injection device. [Figure 2D] Figure 1 is an example of a side view showing a typical use of the injection device. [Figure 3] This is a perspective view of the accessories for the injection device, which are in a closed configuration. [Figure 4] This is a perspective view of the accessories in the open configuration. [Figure 5] This is a perspective view of an open-configuration accessory that includes an injection device within the accessory. [Figure 6]This is a perspective view of a closed-configuration accessory that includes an injection device within the accessory. [Figure 7] This is an internal diagram of the injection device and accessories without a cover. [Figure 8] This is an enlarged perspective view of the accessory cap removal device and cover in the open position; the main body is not shown. [Figure 9] This is a further enlarged perspective view of the cap removal device and cover; the main body is not shown. [Figure 10] This is a further perspective view of the accessories in an open configuration, with the injection device located inside the accessories. [Figure 11] This is a perspective view of the cap removal device and cover in the closed position; the main body is not shown. [Figure 12] This is a perspective view of the base of the accessory. [Figure 13] This is an internal diagram of the main body of the accessory. [Figure 14] This is a plan view of the accessory cap removal device. [Figure 15] This is a further perspective view of the main body. [Modes for carrying out the invention]

[0020] Figures 1A and 1B show a manual injection device 100 suitable for use with the accessories of this disclosure. The injection device 100 extends from the proximal end, which has a needle 130, to the distal end with an opening. It is equipped with a syringe 110. The distal end of the syringe opening is sealed by a stopper 140. Needle The cap 190 is positioned to cover the needle 130.

[0021] The syringe 110 is fixed inside the syringe sheath 120 by the syringe locking element 125. The syringe lock element 125 is provided with contact surfaces that are opposite each other in the diametrical direction. The flange of a standard syringe is restricted between these surfaces. By restricting movement, the syringe 110 does not move relative to the syringe sheath 120. I'll do that.

[0022] The syringe sheath 120 is the distal end of the opening, into which the syringe 110 is inserted. A distal opening end and a proximal opening end that allow the syringe 110 to be inside the sheath 120 When fixed in place, it has an opening proximal end from which the needle 130 extends. The 150 is movably mounted on the syringe sheath 120. Lud 150 is in a retracted position where needle 130 extends beyond the proximal end of the safety shield (Figure) (Figure 1A) and the extension position where the safety shield extends beyond the proximal end of the needle 130 (Figure It is movable between (as shown in Figure 1B) and . In the second position shown in Figure 1B, needle 13 The 0 is covered by a safety shield 150, thereby shielding the user from the needle. This prevents injuries caused by needle punctures in accidents.

[0023] The user grasps the injection device 100 equipped with a conventional dirt grip (shown in Figure 2). Therefore, the safety shield 150 has a flange 155 at its distal end or in that direction. It is equipped with. The flange 155 shown in Figure 1 extends from the safety shield 150. .

[0024] The safety shield 150 is supported by the biasing element 160, which supports the syringe sheath 120 (Figure 1B). The biasing element is biased at its extended position relative to the (indicated). The biasing element is shown in Figures 1A and 1B. 160 is a coil positioned between the syringe sheath 120 and the safety shield 150. Taking the form of a pull, the safety shield 150 is thus positioned relative to the syringe sheath 120. It is biased towards its proximal position and its extended location.

[0025] The releaseable locking mechanism 180 is securely positioned in its retracted position relative to the syringe sheath 120. The entire shield 150 is held. The locking mechanism 180 ensures that the safety shield 150 is syringe-safe. A locked position (Figure 1A) in which the locking mechanism 180 prevents movement relative to the 120, and The locking mechanism 180 prevents the safety shield 150 from moving relative to the limb sheath 120. It is movable between the unlocked position and the unlocked position. Once the locking mechanism is engaged, When moved to the release position, the safety shield 150 is under the influence of the coil spring 160. It moves towards that extended position (Figure 1B).

[0026] In the apparatus shown in Figures 1A and 1B, the safety shield 150 and syringe sheath 120 The locking mechanism 180 between the two is provided on the safety shield 150 and a pair of flexible racks It takes the form of a latch arm 181, which is on the opposing latch surface 183 on the syringe sheath 120. The flexible latch arms 181 engage with their individual latch surfaces 183. It is biased to the first position, and thus the safety mechanism is applied to the syringe sheath 120. Movement of the holder 150 to the proximal position is prevented. The flexible latch arm 181 resists this bias. When moved, the latch arm 181 disengages from its individual latch surfaces 183. This allows the safety shield 150 to move proximal to the syringe sheath 120. do.

[0027] The latch arm 181 is moved by the plunger rod 170 from the first position to the second position It is configured to move to the following. The plunger rod 170 is located at its proximal end. An elongated member configured to engage with the stopper 140, and which disperses the volume of the drug from the needle 130. To deliver the required amount, move the stopper 140 proximal to the longitudinal axis of the syringe body. It is equipped with a member. At its distal end, or in that direction, the plunger rod 170 has The working surface 175 is configured to deliver the injectable drug by moving the plunger rod 170 in the proximal direction. An operating surface 175 is provided on which the user can place their thumb or finger to drive the mechanism. The plunger rod 170 approaches the end of its movement within the syringe body, or here When they reach the working surface 175 of the plunger rod 170, they are connected to the syringe sheath 1 The flexible latching arm extends outward to a position where it is no longer engaged with the latch surface 183 on 20. The Mu 181 is deflected. In this way, the locking mechanism is released at the end of the injection, and the safety shield is released. 150 moves to its extended position.

[0028] Although not visible in the attached drawings, the manual injection device shown in Figures 1A and 1B is used after the injection is complete. The safety shield 150 may further be provided with a safety lock to lock it in its extended position. can.

[0029] Referring to Figure 3, the UltraSafe™ device and other injection devices 100 are used in the injection device 100. There is an accessory 200. In this specification, accessory 200 is a specific example of the injection device 100 and The description uses UltraSafe (trademark). However, accessory 200 is It can be used with injection devices other than UltraSafe® devices. For example, accessories can be used with other injection devices. It can be used with UltraSafe Plus® devices. The structure of accessory 200 is, It can be modified to match the form factor of any suitable injection device.

[0030] The accessory 200 comprises the main body 202 and the cover 204. The accessory 200 is an injection The distal end 206 is positioned towards or over the injection site when performing the procedure. It has a proximal end 208 opposite the distal end 206. The accessory 200 is a cover 20 4 has a window 210 inside. The main body 202 on the opposite side of the accessory 200 also has another window.

[0031] Referring to Figure 4, the cover 204 is connected to the main body portion 202. Specifically, The bar 204 is pivotally connected to the main body portion 202 around a pair of pivot parts 216. Each of the moving parts 216 is positioned facing each side of the accessory 200. Part 216 includes an opening 218 in the main body part 202, and the protruding part 203 inside the cover 204 It penetrates this. Alternatively, the protruding part 203 is located in the main body part 202, and the opening 218 is It may be provided within the bar 204. The protrusion 203 is shown in detail in Figures 8 and 9. Part 203 is rotatable within the opening 218, thereby allowing the cover 204 to rotate within the main body. It can rotate relative to 202. In this way, the cover 204 is open to the position shown in Figure 4. It is movable between the open position and the closed position shown in Figure 3.

[0032] The opening 218 of each pivot part 216 is connected to the main body part 202 by an elastic mounting member 21 It is provided on 7. In this example, the elastic mounting member 217 is integral with the main body portion 202. The elastic mounting member 217 is formed. The elastic mounting member 217 is positioned to bend relative to the main body portion 202. As a result, the cover 204 can be inserted between the pivot parts 216. The process is simplified. In addition, each protrusion 203 on the cover 204 is on the longitudinal surface. It has a surface and sides. The sides are inclined with respect to the longitudinal surface. In other words, the sides are It is not perpendicular to the longitudinal surface. In this way, the protrusion is such that the cover 204 is part of the main body. The elastic mounting member 217 is assisted in bending when it is attached to part 202.

[0033] The main body portion 202 is provided with a recess 220 for receiving the injection device 100. Figure 5 shows the recess. The injection device 100 is located within section 220, and the length of the safety shield 150 is within the recess. It is located in the longitudinal direction within 220. Referring again to Figure 4, the main body portion 202 is It also features a slot 222. The length of the slot 222 is relative to the longitudinal axis of the accessory 200. They are positioned vertically. Slot 222 is the franc of the injection device 100, as shown in Figure 5. It is adapted to accept J155.

[0034] When the cover 204 is in the open position, the recess 220 and slot 222 are located in the injection device 10 It is exposed to receive 0. Specifically, the recess 220 receives the safety shield 150. The slot 222 receives the flange 155. As shown in Figure 6, the injection device 100 When positioned within the recess 220 and slot 222, the cover 204 moves from the open position to the closed position. It is moved to the chain position. The injection device 100 and its accessories 200 are now ready for injection. The setup is complete. The user places the accessory 200, which houses the injection device, on the injection site, for example, on the skin. To administer injections in a safe, simple, and reliable manner, the operating surface 175 is operated with one hand. It can be done.

[0035] When the cover 204 is in the closed position, the cover 204 protects the injection device 100 from the main body portion 20 To hold it in place, the recess 220 and slot 222 are closed. The injection device 100 is covered -When held within the accessory 200 by 204 and the main body portion 202, the injection device 100 This can be seen through the windows 210 provided on each side of the accessory 200. Before administering the injection, the user can examine the contents of the syringe.

[0036] Referring to Figures 4 and 5, slot 222 is distal to the flange 155 of accessory 200. It is molded to resist movement toward end 206. In other words, Lot 222 is molded to prevent flange 155 from moving distally. Slot 222 also moves flange 155 toward the proximal end 208 of attachment 200 It is molded to resist movement. In other words, slot 222 is franc The 155 is molded to prevent it from moving in the proximal direction. However, the slot T222 is that the syringe sheath 120 of the injection device 100 is in the proximal direction relative to the main body portion 202. It is molded to allow movement to the above. As shown, it becomes possible to move from the pre-injection position to the lockout position. In the embodiment, a cavity is formed within the main body portion 202 and the cover 204, and the syringe The creature can move through this cavity. However, the width of this cavity is flat. The 155 cannot move through the cavity, and therefore the cover 204 is in the closed position. While in this position, flange 155 is held within slot 222.

[0037] Referring again to Figure 3, the main body portion 202 and the cover 204 form a pair of opposing sides. They are connected together for this purpose. The right side 212 is shown in Figure 3. The opposite left side is not shown, but the right This is a mirror image of side 212. The accessory 200 has a pair of opposing surfaces. Front surface 214 is shown in Figure 3. The opposing back surfaces are not shown. Each of the opposing surfaces has a similar surface area, and each is... It has a larger surface area than each of the opposing sides. The cover 204 covers a portion of the front 214. The main body portion 202 forms the back surface. These surfaces and sides are the distal end of the accessory 200. The part 206 is connected to the proximal end 208 of the accessory 200.

[0038] The injection device 100 is lowered diagonally into the recess 220, It is positioned at 20. The injection device 100 is positioned in the recess 220. The direction in which 100 is moved toward accessory 200 is perpendicular to the longitudinal axis of accessory 200. The components are arranged in a straight direction, and the components are arranged in a direction parallel to the longitudinal axis of the accessory 200. It has. This direction extends toward the back of the main body portion 202. Specifically, slot 222 and recess 220 are parallel to the surface of accessory 200 from which the injection device 100 is lowered. It has an open surface. The surface of accessory 200 has a larger surface area than the side surface, When positioning the injection device 100 within the accessory 200, the user should target a different area than the accessory 200. It shows a large surface area. This allows users, especially those with dexterity issues, to use the injection device 1 00 can be positioned more easily.

[0039] Referring to Figure 4, the slot 222 has a pair of distal contact portions 2 on both sides of the main body portion 202. It comprises 24. The distal contact portion 224 is fixed to the main body portion 202, and the distal contact portion 224 Each of the flanges resists the distal movement of each of the flanges 155. The distal contact portion 224 is integrally formed with the main body portion 202, making manufacturing easy. , providing a secure connection. However, the main body portion 202 has a distal contact portion 224 that is the main body. It may be a modular component that is removable from part 202. Each distal contact portion 22 4 has a flat upper surface that extends into the curved lower surface. This is on the outside of the lower part of the flange. The shape of the surface is reflected, and the injection device 100 is securely fixed to the main body part 202. We will support you.

[0040] Slot 222 also includes a pair of proximal contact portions 226. The proximal contact portions 226 are Fixed to the body portion 202, one of each of the proximal contact portions 226 is that of the flange 155. Each resists movement in the proximal direction. The proximal contact portion 226 is the main body portion 202 Each is formed integrally, making manufacturing easy and resulting in a secure connection. However, The main body portion 202 has a proximal contact portion 226 that is detachable from the main body portion 202. It may be a Joule-type component. Each proximal contact portion 226 is one of the flanges 155 It has a flat lower surface for interacting with the upper surface. The proximal contact portion 226 is on the syringe sheath 1 They are spaced apart from each other to form a cavity through which 20 can move.

[0041] Referring to Figure 4, the cover 204 has a cover slot 228. Part 228 is when the cover 204 moves from the open position shown in Figure 4 to the closed position shown in Figure 6. Sometimes, it is positioned to hold the flange 155. The cover slot 228 is the cover When 204 is in the closed position, flange 155 faces the distal end 206 of accessory 200. It is molded to resist movement. In other words, cover slot 22 8 is molded to prevent flange 155 from moving distally. Lot 228 also moves flange 155 toward the proximal end 208 of attachment 200 It is molded to resist being flat. In other words, the cover slot 228 is flat The 155 is molded to prevent it from moving in the proximal direction. However, the cover - Slot 228 is the position of the syringe sheath 120 of the injection device 100 relative to the main body portion 202. It is shaped to allow movement in the proximal direction. This allows the injection device 100 to As mentioned above, it becomes possible to move from the pre-injection position to the lockout position. In a particular example, the cover slot 228 works in cooperation with the slot 222 of the main body portion 202. This forms a cavity through which the syringe sheath 120 can pass and move. However, the width of the cavity is Therefore, the flange 155 cannot move through the cavity, and thus the cover 204 is closed. While in the chain position, flange 155 is held within cover slot 228.

[0042] The cover slot 228 also includes a pair of distal contact portions 230 on both sides of the cover 204. The distal contact portion 230 is fixed to the cover 204, and each of the distal contact portions 230 This resists each flange 155 from moving distally. Distal contact portion 230 is integrally formed with cover 204, making it easy to manufacture and providing a secure connection. It brings about. However, the cover 204 is removed from the distal contact portion 230 It may be a removable, modular component. As shown in Figure 4, each distal contact portion 23 0 has ribs that extend along the length of cover 204, and thus structured in cover 204. To provide support.

[0043] The cover slot 228 also includes a pair of proximal contact portions 232. 2 is fixed to cover 204, and one of each of the proximal contact portions 232 is on flange 155 Each resists movement in the proximal direction. The proximal contact portion 232 is the cover 20 Each of the four components is integrally formed, making manufacturing easy and resulting in a secure connection. However, Furthermore, the cover 204 has a proximal contact portion 232 that is removable from the cover 204. It may be a turret-type component.

[0044] Referring to Figures 7 and 8, the accessory 200 extends the needle cap 190 from the injection device 100. It is equipped with a cap removal device 234 for removing the cap. The cap removal device 234 is In this example, a pair of gripping ends for interacting with the needle cap 190 It is equipped with a movable element 236. Each gripping end is attached to the outer surface of the needle cap 190. It is shaped to do so. Each gripping end is joined to the cylindrical outer shape of the needle cap 190. It has a concave end. In this example, the movable element 236 is connected to the cap removal device 234. They are formed as a single unit. However, the movable element 236 is attached to the cap removal device 234. In contrast, they may be provided as separate components that bend or rotate. For example, each movable element 23 6 may be mounted on the cap removal device 234 with the pivot part as the center. Needle cap 190 This may be a rigid needle cap or a non-rigid needle cap. The rigid needle cap is at least It may be formed of two components, for example, a rigid outer shell and when in a given position It may include an inner body surrounding the needle 130 on the syringe 110. The inner body is flexible It may be a side body, an elastic inner body, or a flexible inner body. This inner body is made of rubber. It may also be the side body. Alternatively, a non-rigid needle cap may be used, in which case the needle key A cap is a single flexible body, elastic body, or pliable body, for example, a rubberized needle boot. This may be the case. In the case of a non-rigid needle cap, the cap removal device 234 removes the cap. During removal, for example, the non-rigid needle cap is elastically gripped between a pair of movable elements 236. It is designed to fit in such a way. The cap is not rigid, so the grip is tight and snug. Therefore, to ensure that the cap is removed, the cap removal device 23 It deforms within part 4, especially within the gripping section.

[0045] In this example, the cap removal device 234 has an expanded configuration (as shown in Figure 8) and a contracted configuration. It has a configuration (not shown). In the extended configuration, the cap removal device 234 has a needle cap It does not interact with the pin 190. Specifically, the needle cap 190 does not interact with the cap removal device 2. When 34 is in an extended configuration, for example, when the injection device 100 is inserted into the recess 220 In addition, it can pass through the movable element 236, that is, it can pass through the movable element 236. In this configuration, the cap removal device 234 is connected to the injection device 10 The needle cap 190 is held in place so that it can be removed from the needle cap 190. Specifically, the movable element 236 is connected to the cap removal device 234 via the gripping end of the needle cap To assume a retractable configuration that grips the top 190, they move toward each other. Cover 204 When in the open position, the cap removal device 234 is in the extended position. Close the cover 204. By locking, the cap removal device 234 slides forward to remove the needle cap 190. When removed, it adopts a contracted configuration. However, the cap removal device 234 is (Figure 6) (As shown) When cover 204 is completely closed, release needle cap 190. To do this, we will take on an extended configuration again.

[0046] In this particular example, the gripping portion has two configurations: an expanded configuration and a contracted configuration. However, in another example, the gripping part may be in a retracted configuration by default. In this case, the gripping part The injection device 100 holds the needle cap 190 when it is placed inside the accessory 200, and expands There is no need to transition from a tensioned to a shrunk configuration. This option may make manufacturing simpler. However, when the gripping part takes an expanded configuration, the injection device 100 does not receive resistance from the gripping part. This allows for insertion into accessory 200. In another example, the gripping part is directed toward the non-movable element. It may have only one movable element, such as a push button.

[0047] The cap removal device 234 is positioned within the track of the main body portion 202. It is equipped with a pair of guides 240 that are positioned accordingly. The cap removal device 234 is the main body part It is positioned to slide within track 202.

[0048] Referring to Figures 9 and 10, the cap removal device 234 is a cap removal device Each of the 234 is provided with a pair of cap removal device slots 242. To move the cover 204 from the open position to the closed position, the cover 204 is used by the user. It includes a proximal end 244 that can be moved by a cap removal device 234 and a movable part. To move the gripping portion including element 236 distally, the cover 204 also removes the cap. It includes a distal end 246 that is operably connected to a detachment device 234.

[0049] In this example, a pair of distal ends 246 of the cover 204 are present, and the cap removal device Each of the lots 242 has a cover cam 243 located inside it. As the cover 204 pivots from the open position to the closed position, the cap removal mechanism To translate the position 234 distally, each distal end 246 is a cap removal device slot It connects to one of each of the T242. Figure 11 shows the cover 204 in the closed position. The cap removal device 234 is being moved distally.

[0050] Referring to Figure 9, each cover 204 is positioned distally from each pivot 216. It has a pair of distal extensions that extend outwards. The distal end 246 and the cover cam 243 are distal extensions It is located on the long part. A pair of proximal extensions are provided, each corresponding to one of the distal extensions. It exists. Each proximal extension extends proximally away from each pivot 216, thereby These form two sides of the proximal end 244 of the cover 204.

[0051] Each proximal extension is longer than each distal extension. This is related to the mechanical aspects of the pivot 216. This helps to bring about advantages, and therefore, the cover 204 can be closed more easily. Furthermore, the cap removal device 234 is moved distally to remove the needle cap 190. It is especially important for travel.

[0052] Referring to Figures 8 and 14, one of the movable elements 236 of the gripping section is a flexible elastic It is made of a material. This allows the gripping part to allow the needle cap 190 to pass between the gripping parts. An extended configuration that allows, that is, allows the needle cap 190 to pass through, and the injection device 100 The gripping part is a retractable configuration that holds the needle cap 190 in order to remove it, and can be moved between these two. A cap removal device cam 248 is located on one outer surface of each of the movable elements 236. Each cap removal device cam 248 is connected to the cap removal device 234, which is connected to the cover 204. When moved distally by the main body portion 202, the cap removal device cam surface 2 It connects to 50. The cap removal device cam surface 250 is shown in Figures 12 and 13. The cap removal device 234 also removes the cover 204 when it is in the closed position. It comprises a pair of receptive slots, each adapted to receive at least a portion of the .

[0053] The cap removal device cam 248 is pressed against the cap removal device cam surface 250. Then, the cap removal device 234 moves forward in the distal direction. This expands the gripping portion. To transition from the expanded to the contracted configuration, the movable elements 236 are pushed toward each other. When the injection device 100 is inside the recess 200, the movable element 236 grasps the needle cap 190. It holds. At the same time, the cap removal device 234 is moved distally, therefore Pull the needle cap 190 distally and away from the injection device 100. The needle cap 190 is removed from the injection device 100.

[0054] Referring to Figures 12 and 13, one of the cap removal device cam surfaces 250 When the cover 204 moves from the open position to the fully closed position, the gripping portion expands from its extended configuration. It is molded to transition to a contracted configuration and then back to an expanded configuration. In this example, the cap is removed. Each of the removal device cam surfaces 250 is one of the cap removal device cams 248 Proximal end 252 and distal end 254 that do not interact with one of them, and cap removal device 23 To move the movable element 236 when 4 moves distally, the cap removal device It has an intermediate portion 256 positioned to interact with one of each of the cams 248. ru.

[0055] Figure 8 shows the cover 204 in the fully open position, and the cam removal device 234 in an extended configuration. It is located in Figure 12, which shows the cover 204 in the fully closed position, and the cam removal device is located in the cover - When 204 moves from the fully open position to the fully closed position, it returns from the retracted configuration to the extended configuration. It is.

[0056] Referring to Figure 15, the main body portion 202 is the respective gas of the cap removal device 234 It is equipped with a pair of tracks 258 for receiving Id 240. Each track 258 is for injection When the device 100 is positioned on the main body portion 202, the cap removal device 234 is positioned on the trap. It is fitted so that it does not come out of the container. This is shown in Figure 10. Specifically, the injection device 100 When the injection device 100 is in the recess 220, the cap can be removed from each track 258. Hold device 234.

[0057] Each track 258 is used when the injection device 100 is not located on the main body 202. The top removal device 234 has components that are perpendicular to the axial direction (i.e.) (The accessory 200 moves in the longitudinal direction, extending from the proximal end 208 to the distal end 206.) It is configured so that it is possible. However, the injection device 100 is located in the main body part 202. When positioned, the cap removal device 234 is moved by the injection device 100 to each track 258 It is pressed against, and as a result, the cap removal device 234 is axially positioned relative to the main body portion 202. It can only slide in that direction.

[0058] As shown in Figure 7, each track is when the injection device 100 is positioned in the recess 220. The injection device 100 has a cap removal device 234 inside the track 258, at least partially. At least a portion of the cap removal device 234 is exposed so as to hold it in place. As shown in 10, each track 258 contacts the upper surface of the cap removal device 234. Since it does not include means adapted to such a purpose, track 258 does not include the cap removal device 234 To expose. In other words, the main body part 202 has a cap removal device 2 It does not have a lip or other such retaining means for holding 34. Instead, the injection device 1 00 holds the cap removal device 234 inside the track 258. Specifically, The top removal device 234, when the injection device 100 is positioned in the recess 220, It makes direct contact with 100. This simplifies the design of accessory 200.

[0059] Referring to Figure 15, each track 258 has a base 260 and a cap removal device 23 It comprises a pair of side walls 264, 266 adapted to guide each side of 4. In this example, the pair of side walls 264 and 266 are formed integrally with the main body portion 202. In another example, one or both of the side walls 264, 266 are separate from the main body portion 202. These are components. One of the first side walls 266 of each track 258 is fitted with an injection device 100. When inside item 200, define the wall of window 268 from which the injection device 100 can be seen. One of the second side walls 264 of each track 258 defines the outer side wall of the accessory 200. The base 260 and / or side walls 264, 266 of track 248 are integral with the main body portion 202. It is formed in this way.

[0060] The features of the above accessory 200 are that it is inexpensive, simple, and easy to use. In addition, in order to administer an injection using the injection device 100, the accessory 200 can be operated with one hand. This is possible.

[0061] When using the above injection device, it is used for rheumatoid arthritis, psoriatic arthritis, ankylosing spondylitis, and ulcerative colitis. Colitis, hormone deficiency, poisoning, pain, thrombosis, infection, diabetes, diabetic retinopathy, acute Coronary artery syndrome, angina pectoris, myocardial infarction, atherosclerosis, cancer, macular degeneration, allergy - For the treatment or prevention of hay fever, inflammation, anemia, or myelodysplasia, or for protective immunity Antibodies (monoclonal antibodies, ustekinumab, golimumab, etc.) for use in expression Fliximab, guselkumab, silkumab, adalimumab, rituximab, tocilizumab , centrizumab, centrizumab pegol, sarilumab, secukinumab, ixekizumab , or biosimilar versions thereof, etanercept, abatacept, ana Kinra, epoetin alfa, darbepoetin alfa, epoetin beta-methoxypo Ethylene glycol, peginesatide, hormones, antitoxins, pain control substances, thrombosis control Substances for use, substances for controlling or eliminating infectious diseases, peptides, proteins, human insulin or human Insulin analogs or derivatives, polysaccharides, DNA, RNA, enzymes, oligonucleotides Antiallergic drugs, antihistamines, anti-inflammatory drugs, corticosteroids, disease-modifying anti-inflammatory drugs It contains and is used to deliver substances such as anticoagulants, erythropoietin, or vaccines. Obtain. In addition to these substances, any drugs contained in the infusion device are also as those skilled in the art will understand. It may contain other substances such as inactive ingredients, as is expected. As is well known in the field, certain substances are used in the treatment or prevention of certain conditions. Those skilled in the art will understand that it is effective for this purpose. For example, anti-allergic Ghee drugs are effective in treating or preventing allergies, while antihistamines are used for pollen allergies. It is effective for use in the treatment or prevention of the disease, and anti-inflammatory drugs are used for the treatment or prevention of inflammation. It is known to be effective for [specific purpose]. Therefore, these substances (including multiple substances) are effective. For use in the treatment or prevention of one or more conditions that are known to be, Any selection of one or more substances listed in this specification or in the claims Other options are also conceivable. However, in certain cases, golimumab is used for rheumatoid arthritis , one or more of the following: psoriatic arthritis, ankylosing spondylitis, or ulcerative colitis, Or any combination of rheumatoid arthritis, psoriatic arthritis, ankylosing spondylitis, and ulcerative colitis. , or treatment of all rheumatoid arthritis, psoriatic arthritis, ankylosing spondylitis, and ulcerative colitis or It is known to be effective for use in prevention.

[0062] Golimumab contains L-histidine, L-histidine monohydrochloride monohydrate, sorbitol, and One or more inactive ingredients, such as Resorbate 80 and water, or all of them. It may be used in combination with other substances as desired. Golimumab is the sole active ingredient. It may be present in a certain composition. For example, golimumab may be SIMPONI®. It may be administered.

[0063] The term "comprising" includes "including" and "consisting of". "Consisting" means "to include," for example, a combination of "compositions" that "include" X. The resulting product may consist exclusively of X, and may include some additional components such as X + Y. Unless otherwise stated, each embodiment described herein is a different embodiment described herein. It may be combined with other forms. In the specific embodiment described above, in order to achieve a specific function, We provided pairs of components. However, at least one of these components These functions can be achieved using this method.

[0064] The above benefits and advantages may relate to one embodiment or to several embodiments. It will be understood that they may be linked. The embodiments may address any or all of the problems described. Limited to those that resolve the issue or have any or all of the stated benefits and advantages. It is not done. A reference to an item "an" refers to one or more of those items. .

[0065] The above description of preferred embodiments is given merely as examples and will be understood by those skilled in the art. It will be understood that various modifications may be made. Various embodiments, to a certain extent. As described above with respect to the specific characteristics of one or more individual embodiments, This involves making numerous modifications to the disclosed embodiments without departing from the scope of the present invention. It is possible.

[0066] List of numbered embodiments 1. An accessory for an injection device having a needle cap, the accessory is, A main body portion having a recess adapted for receiving an injection device, A cover connected to the main body, the cover having a recess that is exposed to receive the injection device. The open position and the cover holding the injection device to the main body by at least partially closing the recess. A cover that can pivot between a closed position and a closed position, A cap removal device comprising a gripping portion adapted to hold a needle cap, The cap removal device is movable relative to the main body, and Prepare, The cover is, The cover is adapted to be moved by the user, from the open position to the closed position. The proximal end, When the cover moves from the open position to the closed position, the gripping part moves towards the end of the accessory. The distal end is fitted to at least partially remove the needle cap from the injection device. Accessories that include a part.

[0067] 2. The cover is connected to the main body portion around at least one pivot point, in Embodiment 1. The accessories listed.

[0068] 3. At least one pivot part, At least one opening in the main body, At least one protrusion within the cover, the at least one protrusion within the opening The accessory according to Embodiment 2, further comprising at least one rotatable projection.

[0069] 4. The cover extends distally from at least one pivot point, at least one It has two distal extensions, and the distal end of the cover is provided at the end of the distal extension, Accessories as described in Embodiment 2 or Embodiment 3.

[0070] 5. The cover comprises a proximal extension that extends proximal to at least one pivot point. The accessories described in any one of embodiments 2 to 4.

[0071] 6. The distal extension is shorter than the proximal extension, as described in Embodiments 4 and 5. .

[0072] 7. The distal end of the cover is located inside the cap removal device slot of the cap removal device. An accessory according to any one of embodiments 1 to 6, comprising a positioned cover cam.

[0073] 8. To move the cap removal device within the accessory, the cover is pivoted around the pivot axis. The rotation of the cam causes the cover cam to act against the cap removal device slot, Accessories as described in Form 7.

[0074] 9. To move the cap removal device toward the distal end of the accessory, the cover is moved. It pivots from the open position to the closed position, and the cover cap is opposed to the cap removal device slot. An accessory according to Embodiment 7 or Embodiment 8, which is arranged to activate the mechanism.

[0075] 10. The gripping part moves toward the distal end of the accessory when the cap removal device slot moves toward the distal end of the accessory. While doing so, hold the needle cap and remove it at least partially from the syringe. The accessory described in Embodiment 9, which is arranged in the same manner.

[0076] 11. To move the cap removal device toward the proximal end of the accessory, the cover is It pivots from the closed position to the open position, and covers the cap removal device slot. An accessory according to any one of embodiments 7 to 10, which is positioned to actuate the cam.

[0077] 12. The cover is connected to the main body by a pair of pivot parts, as in Embodiments 1 to 11. The accessories listed in one of the items.

[0078] 13. Each of the pair of pivot parts is provided with an opening in the main body and a protrusion inside the cover. The accessory according to embodiment 12, wherein the protruding portion is rotatable within the opening.

[0079] 14. The cover extends distally from each of the pair of pivots. The accessory according to Embodiment 12 or Embodiment 13, comprising a pair of distal extensions.

[0080] 15. The cover extends proximal to each of the pair of pivots. An accessory according to any one of embodiments 12 to 14, comprising a pair of proximal extensions.

[0081] 16. Each distal extension is shorter than the corresponding proximal extension in Embodiments 14 and 1 Accessories as listed in item 5.

[0082] 17. A pair of distal ends of the cover, each provided at one end of the distal extension. It further comprises a section, one of which at each distal end, the cover moves from an open position to a closed position. Then, move the gripping part toward the end of the accessory and remove the needle cap from the injection device at least Embodiment 14, which is operably connected to a cap removal device to partially remove the cap, And optionally, the accessories described in Embodiment 15 and / or Embodiment 16.

[0083] 18. Each distal end of the cover is connected to the corresponding cap removal device. The accessory according to embodiment 17, comprising a cover cam positioned within a removal device slot.

[0084] 19. To move the cap removal device within the accessory, each of the pivots around the pivot axis The rotation of the bar cam opposes the corresponding cap removal device slot for each cover An accessory described in Embodiment 18 for operating the cam.

[0085] 20. To move the cap removal device toward the distal end of the accessory, the cover is It pivots from the open position to the closed position, opposing the corresponding cap removal device slot. The respective cover cams are arranged to act, as described in Embodiment 18 or Embodiment 19. accessories.

[0086] 21. The gripping part moves toward the distal end of the accessory when the cap removal device slot moves toward the distal end of the accessory. The needle cap is held in place while the needle cap is removed from the injection device. Accessories as described in Installation Form 20.

[0087] 22. To move the cap removal device toward the proximal end of the accessory, the cover is It pivots from the closed position to the open position, opposing the corresponding cap removal device slot. As described in any one of embodiments 18 to 21, each cover cam is positioned to act. Included accessories.

[0088] 23. The cap removal device has an extended configuration that allows the needle cap to pass between the gripping parts. The gripping part holds the needle cap and removes at least partially the needle cap from the injection device. An accessory according to any one of embodiments 1 to 22, having a removable shrinkage configuration.

[0089] 24. The cover and cap removal device moves the cover from the open position to the closed position. When moved, the cap removal device can be operated to transition from an extended configuration to a retracted configuration. Accessories according to embodiment 23, which are connected to each other.

[0090] 25. The cap removal device returns to its extended configuration when the cover reaches the closed position, and the needle An accessory according to embodiment 23 or embodiment 24, which is positioned to release the cap.

[0091] 26. The gripping part holds the needle cap when the cap removal device is in its retracted configuration. The cap removal device is offset from the needle cap when it is in the extended configuration. A modified, at least one movable element is provided in any one of embodiments 23 to 25. The accessories listed.

[0092] 27. At least one movable element is formed from a flexible elastic material, and the flexible elastic material The material has at least one movable element, which is positioned so that the gripping part holds the needle cap, and the needle cap The attachment described in Embodiment 26 is movable between a position where it can pass between the gripping parts and Item.

[0093] 28. At least one movable element is positioned such that the gripping part holds the needle cap, and the needle cap The implement is configured to bend between the gripping parts in a position where it can pass between them. Accessories as described in Form 27.

[0094] 29. To transition the cap removal device from the expanded configuration to the contracted configuration, at least Another cap removal device is positioned to interact with the cam surface, at least one One of embodiments 23 to 28 further comprises a cap removal device cam. Accessories.

[0095] 30. At least one cap removal device cam is connected to at least one movable element. Embodiments 26 and 2 are connected or provided on at least one movable element. 9, and optionally the accessories described in Embodiment 28 and / or Embodiment 27.

[0096] 31. The cap removal device cam surface is connected to the main body or on the main body. An accessory provided as described in Embodiment 29 or Embodiment 30.

[0097] 32. At least one cap removal device cam surface is a cap removal device cam As it moves across the surface of the cap removal device cam, the cap removal device expands as it passes through. To transition from a taut configuration to a deflated configuration and then back to an expanded configuration, the cap removal device cam and An accessory according to any one of embodiments 29 to 31, arranged to interact with each other.

[0098] 33. At least one cap removal device cam and at least one cap removal device The cam surfaces of the removal device are offset from each other when the cover is in the open position, in practice. Accessories listed in one of the following descriptions (29-32).

[0099] 34. The movement of the cover from the open position to the closed position moves the cap removal device cam. The cap removal device engages with the cam surface, and as a result, the cap removal device expands An accessory according to any one of embodiments 29 to 33, which transitions from a solid state to a shrinkable state.

[0100] 35. The gripping portion is molded to match the outer surface of the needle cap, and at least one An accessory according to any one of embodiments 23 to 34, comprising a gripping end.

[0101] 36. The gripping part holds the needle cap when the cap removal device is in its retracted configuration. The cap removal device is offset from the needle cap when it is in the extended configuration. An attachment described in any one of embodiments 23 to 35, comprising a pair of movable elements that have been adapted. Item.

[0102] 37. Each of the pair of movable elements is formed from a flexible elastic material and is flexible elastic The material is such that each movable element is positioned such that the gripping part holds the needle cap, and the needle cap is part of the gripping part An accessory according to embodiment 36, which is movable between a position that can pass through and a position that can move between two positions.

[0103] 38. Each of the pair of movable elements is positioned such that the gripping part holds the needle cap, and the needle The cap is configured to bend between a position where it can pass between the gripping parts. Accessories as described in Embodiment 36 or Embodiment 37.

[0104] 39. A pair of such devices are used to transition the cap removal device from an expanded configuration to a contracted configuration. Each is positioned to interact with one of the surfaces of the cap removal device cam. Any one of embodiments 23 to 36 further comprises a pair of cap removal device cams. Accessories as listed below.

[0105] 40. Each cap removal device cam is connected to one of the movable elements. Alternatively, they are provided on each of the movable elements, Embodiment 36, Embodiment 3 9, and optionally the accessories described in Embodiment 37 and / or Embodiment 38.

[0106] 41. The cam surface of each cap removal device is connected to the main body or on the main body. An accessory provided in the embodiment described in embodiment 39 or embodiment 40.

[0107] 42. The surface of the cap removal device cam is such that the cap removal device cam is on each cap The cap removal device moves along the surface of the cam, and as it passes, the cap removal device expands its configuration. Embodiments 39-41 are arranged to transition from a contracted configuration to an expanded configuration and then back to an expanded configuration. The accessories listed in one of the items.

[0108] 43. Each cap removal device cam and the corresponding cap removal device cam surface are The bars are offset from each other when in the open position, and as a result, the cap removal process The cam and cap removal device are not joined to each other, as in any of embodiments 39 to 42. Accessories listed on one item.

[0109] 44. The movement of the cover from the open position to the closed position is controlled by each cap removal device. Move the cam to engage with the corresponding cap removal device cam surface, and as a result, the cap is removed. The removal device transitions from an expanded configuration to a contracted configuration, in any one of embodiments 39 to 43. The accessories listed.

[0110] 45. The holding part is a pair of holding end parts, each of which is shaped to conform to the outer surface of the needle cap, and is the accessory according to any one of Embodiments 23 to 44.

[0111] 46. The accessory is for an injection device having a safety shield, at least one flange adapted to allow a user to hold the injection device, and a syringe sheath movable from a pre-injection position to a locked-out position with respect to the at least one flange, and the body portion further comprises a slot adapted to receive at least one flange of the injection device, and is the accessory according to any one of Embodiments 1 to 45.

[0112] 47. The recess and the slot are for receiving the exposed safety shield and at least one flange respectively when the cover is in the open position, and are the accessory according to Embodiment 46.

[0113] 48. The cover is for at least partially closing the recess and the slot when the cover is in the closed position to hold the injection device within the accessory, and is the accessory according to Embodiment 46 or Embodiment 47.

[0114] 49. The slot is shaped to resist movement of the at least one flange in the distal and proximal directions with respect to the body portion and to allow the syringe sheath to move proximally with respect to the body portion from the pre-injection position to the locked-out position, and is the accessory according to any one of Embodiments 46 to 48. [[ID=3—6]]

[0115] 50. The distal end of the accessory adapted to be positioned towards the injection site and the proximal end of the opposing accessory ​​​​​​​​​A pair of opposing surfaces, and a pair of opposing side surfaces connecting the distal end of the proximal end of the accessory, further The accessories provided are those described in any one of embodiments 46 to 49.

[0116] 51. Each of the opposing surfaces has a larger surface area than each of the opposing sides. , accessories as described in Embodiment 50.

[0117] 52. One of the opposing surfaces is provided with a cover, as in Embodiment 50 or Embodiment 51. accessories.

[0118] 53. Each slot and recess has an open surface parallel to the surface of the accessory, The accessories listed in one of the following descriptions (50-52).

[0119] 54. The recesses and slots are positioned so that the injection device is perpendicular to the longitudinal axis of the accessory. One of embodiments 46 to 53, which is positioned to receive the injection device when it is moved. Accessories as listed.

[0120] 55. The slot is such that at least one flange moves distally relative to the accessory. Embodiment 46, comprising at least one distal contact portion positioned to resist and Accessories listed in any one of the items ~54.

[0121] 56. At least one distal contact portion of the slot is integrally formed with the main body portion. Accessories as described in Embodiment 55.

[0122] 57. The shape of at least one distal contact portion is the shape of at least one lower surface of a flange. An accessory according to Embodiment 55 or Embodiment 56, which at least partially matches the shape.

[0123] 58. The slot includes at least one proximal abutment portion arranged to resist movement of at least one flange in the proximal direction relative to the accessory. The accessory according to any one of Embodiments 46 to 57, which includes at least one proximal abutment portion arranged to resist movement of at least one flange in the proximal direction relative to the accessory.

[0124] 59. The accessory according to Embodiment 58, wherein at least one proximal abutment portion of the slot is integrally formed with the body portion. The accessory according to Embodiment 58.

[0125] 60. The cover includes a cover slot formed in the cover and arranged to resist movement of at least one flange in both the distal and proximal directions relative to the accessory, while the syringe sheath is shaped to be movable in the proximal direction relative to the accessory from the pre-injection position to the lockout position. The accessory according to any one of Embodiments 46 to 59. The accessory according to any one of Embodiments 46 to 59, which includes a cover slot formed in the cover and arranged to resist movement of at least one flange in both the distal and proximal directions relative to the accessory, while the syringe sheath is shaped to be movable in the proximal direction relative to the accessory from the pre-injection position to the lockout position. The accessory according to any one of Embodiments 46 to 59, which includes a cover slot formed in the cover and arranged to resist movement of at least one flange in both the distal and proximal directions relative to the accessory, while the syringe sheath is shaped to be movable in the proximal direction relative to the accessory from the pre-injection position to the lockout position. The accessory according to any one of Embodiments 46 to 59, which includes a cover slot formed in the cover and arranged to resist movement of at least one flange in both the distal and proximal directions relative to the accessory, while the syringe sheath is shaped to be movable in the proximal direction relative to the accessory from the pre-injection position to the lockout position.

[0126] 61. The accessory according to Embodiment 60, wherein the cover slot is formed within the cover.

[0127] 62. The accessory according to Embodiment 61, wherein the cover slot includes at least one distal abutment portion arranged to resist movement of at least one flange in the distal direction relative to the accessory. The accessory according to Embodiment 61, which includes at least one distal abutment portion arranged to resist movement of at least one flange in the distal direction relative to the accessory. The accessory according to Embodiment 61, which includes at least one distal abutment portion arranged to resist movement of at least one flange in the distal direction relative to the accessory.

[0128] 63. The accessory according to Embodiment 62, wherein at least one distal abutment portion of the cover slot is integrally formed with the cover. The accessory according to Embodiment 62.

[0129] 64. The accessory according to any one of Embodiments 60 to 63, wherein the cover slot includes at least one proximal abutment portion arranged to resist movement of at least one flange in the proximal direction relative to the accessory. The accessory according to any one of Embodiments 60 to 63, which includes at least one proximal abutment portion arranged to resist movement of at least one flange in the proximal direction relative to the accessory. The accessory according to any one of Embodiments 60 to 63, which includes at least one proximal abutment portion arranged to resist movement of at least one flange in the proximal direction relative to the accessory.

[0130] 65. At least one proximal contact portion of the cover slot is integrally formed with the cover. The accessories described in Embodiment 64.

[0131] 66. The accessories are a pair of fittings adapted to allow the user to grasp the injection device. Accessories described in any one of embodiments 46 to 65, for use with a flanged injection device. .

[0132] 67. The slot is located distal to the accessory, with each flange of the pair of flanges positioned distally to the accessory. The implement comprises a pair of distal contact portions, each positioned to resist movement. Accessories as described in Form 66.

[0133] 68. The pair of distal contact portions are integrally formed with the main body portion, as described in Embodiment 67. accessories.

[0134] 69. The shape of each of the pair of distal contact portions is the shape of each of the pair of flanges. The attachment described in Embodiment 67 or Embodiment 68, which at least partially matches the shape of the lower surface. Accessories.

[0135] 70. The slots are located in the direction of each flange of the pair of flanges, proximal to the main body. A real Accessories listed in any one of the installation configurations 66 to 69.

[0136] 71. The pair of proximal contact portions are integrally formed with the main body portion, as described in Embodiment 70. accessories.

[0137] 72. The cover slot is formed by a pair of flanges moving distally relative to the main body. One of embodiments 60 to 71, which includes a pair of distal contact portions arranged to resist the force The accessories listed on one of the items.

[0138] 73. The pair of distal contact portions of the cover slot are integrally formed with the cover, Accessories as described in item 72.

[0139] 74. The cover slot is formed by a pair of flanges moving proximal to the main body. One of embodiments 60 to 73 comprises a pair of proximal contact portions arranged to resist the force The accessories listed on one of the items.

[0140] 75. The pair of proximal contact portions of the cover slot are integrally formed with the cover, Accessories as described in item 74.

[0141] 76. The main body is equipped with tracks arranged so that the cap removal device moves in a translating manner. , The truck is located inside the truck when the syringe is positioned in the recess. The cap removal device is held at least partially, An accessory described in any one of embodiments 1 to 75 that exposes a portion of itself.

[0142] 77. The track is such that when the injection device is positioned in the recess, the cap removal device is An accessory according to embodiment 76, configured to be in direct contact with an injection device.

[0143] 78. The track is equipped with means adapted to contact the upper surface of the cap removal device. Accessories that are not permitted, as described in Embodiment 76 or Embodiment 77.

[0144] 79. The track comprises a base and at least one side wall, according to embodiments 76-78. The accessories listed in one of the items.

[0145] 80. Track is, A base adapted to guide the underside of the cap removal device, At least one side wall adapted to guide the side of the cap removal device, An accessory according to any one of embodiments 76 to 79, comprising:

[0146] 81. At least one side wall is visible when the syringe is inside the accessory. An accessory according to embodiment 80 that defines the wall of a window where it can be made.

[0147] 82. At least one side wall defines the outer side wall of the accessory, as in Embodiment 80. accessories.

[0148] 83. The base and / or at least one side wall is formed integrally with the main body portion. Accessories listed in any one of Forms 80-82.

[0149] 84. The track is adapted to guide each side of the cap removal device. The accessory according to any one of embodiments 80 to 83, comprising a pair of side walls.

[0150] 85. A pair of side walls are integrally formed with the main body portion, in any of embodiments 80 to 84. Accessories listed on one item.

[0151] 86. The main body consists of a pair of tracks arranged so that the cap removal device moves in a translating manner. Equipped with, Each track is where the injection device is positioned in the recess, and the injection device is located within each track. To hold the cap removal device at least partially, An accessory according to any one of embodiments 76 to 85, which exposes at least a portion of the cord.

[0152] 87. Each track is a cap removal device when the injection device is positioned in the recess. The accessory according to embodiment 86, which is configured to be in direct contact with the injection device.

[0153] 88. Each track has means adapted to contact the upper surface of the cap removal device. Accessories described in Embodiment 86 or Embodiment 87 that are not provided.

[0154] 89. Each track comprises a base and at least one side wall, embodiments 86-88 The accessories listed in one of the following items.

[0155] 90. Each track is, A base adapted to guide the underside of the cap removal device, At least one side wall adapted to guide the side of the cap removal device, An accessory according to any one of embodiments 86 to 89, comprising:

[0156] 91. At least one side wall of each track is the injection device when the injection device is inside the accessory. An accessory according to embodiment 90 that defines the wall of a window from which the interior can be seen.

[0157] 92. Each track has at least one side wall that defines the outer side wall of the accessory, Embodiment Accessories as listed in item 90.

[0158] 93. The base and / or at least one side wall of each track is formed integrally with the main body. The accessory described in any one of embodiments 90 to 92.

[0159] 94. Each track is fitted to guide each side of the cap removal device. An accessory according to any one of embodiments 90 to 93, comprising a pair of side walls.

[0160] 95. The pair of side walls of each track are formed integrally with the main body portion, Embodiments 90-9 The accessories listed in any one of the four items.

[0161] 96. The cap removal device is fitted with a guide so that it can be positioned inside the truck. An accessory according to any one of embodiments 76 to 95, comprising:

[0162] 97. The cap removal device, when the cover is in the closed position, at least Embodiment comprising at least one receptive slot adapted to receive a portion The accessory listed in one of the numbers 1 through 96.

[0163] 98. The cap removal device, when the cover is in the closed position, removes at least the cover Embodiment 1 comprises a pair of receiving slots, each adapted to receive a portion. Accessories listed in any one of the ~97 items.

[0164] 99. The main body is fitted with at least one cover that connects to the main body. An accessory according to any one of embodiments 1 to 98, comprising an elastic mounting member.

[0165] 100. The main body part is such that the cap removal device moves axially relative to the main body part. It is equipped with a track that is positioned such that when the injection device is in the main body, The cap removal device is adapted to be pressed against the truck by an injection device. , accessories as described in any one of embodiments 1 to 99.

[0166] 101. The track is such that when the injection device is positioned in the main body, the cap removal device is Accessories as described in Embodiment 100, which are adapted to prevent them from coming off the truck.

[0167] 102. The track is the cap removal device when the injection device is not positioned in the main body. However, it is adapted to be movable in a direction having components that are perpendicular to the axial direction. Accessories as described in embodiment 100 or embodiment 101.

[0168] 103. The track is such that when the injection device is positioned in the main body, the cap removal device is The injection device presses against the truck, and as a result, the cap removal device is pressed against the main body Embodiments 100-10 are adapted to allow movement only in the axial direction relative to the minute. The accessories listed in one of item 2.

[0169] 104. The main body is equipped with tracks on which the cap removal device slides. The accessories described in any one of embodiments 1 to 103.

[0170] 105. At least one cap removal device cam is a cap removal device cam table. The surface is arranged to slide within the slot of the main body portion that accommodates the surface, Embodiment 1 and the embodiment Embodiment 29, and optionally one of Embodiments 2 to 28 and Embodiments 30 to 104 Accessories as listed.

[0171] 106. A system for administering an injection, the system comprising an injection device having a needle cap. A system comprising a stand and an accessory as described in any one of embodiments 1 to 105.

[0172] 107. The injection device is Rheumatoid arthritis, psoriatic arthritis, ankylosing spondylitis, ulcerative colitis, hormone deficiency poisoning, pain Pain, thrombosis, infection, diabetes, diabetic retinopathy, acute coronary syndrome, angina pectoris, myocardial infarction, Atherosclerosis, cancer, macular degeneration, allergies, hay fever, inflammation, anemia, or Antibodies (mono) for use in the treatment or prevention of myelodysplasia, or for the expression of protective immunity. Clonal antibodies, ustekinumab, golimumab, infliximab, guselkumab, sil Kumab, adalimumab, rituximab, tocilizumab, centrizumab, centrizumab Pegol, sarilumab, secukinumab, ixekizumab, or biosimilar bars of these. John (etc.), etanercept, abatacept, anakinra, epoetin alfa, dal Bepoetin alpha, epoetin beta-methoxypolyethylene glycol, Peginesati D, hormones, antitoxins, pain control substances, thrombosis control substances, substances for controlling or eliminating infections Proteins, peptides, proteins, human insulin or human insulin analogs or derivatives, Polysaccharides, DNA, RNA, enzymes, oligonucleotides, antiallergic drugs, antihistamines , anti-inflammatory drugs, corticosteroids, disease-modifying antirheumatic drugs, erythropoietin, or The system according to embodiment 106, comprising a substance selected from the group consisting of cutin.

[0173] 108. Delivery of the substance to a human subject using the system described in Embodiment 106 At night, rheumatoid arthritis, psoriatic arthritis, ankylosing spondylitis, ulcerative colitis, hormone deficiency poisoning. Pain, thrombosis, infection, diabetes, diabetic retinopathy, acute coronary syndrome, angina pectoris, myocardial infarction Cerebrospinal fluid, atherosclerosis, cancer, macular degeneration, allergies, hay fever, inflammation, anemia, if or antibodies used for the treatment or prevention of myelodysplasia, or for the expression of protective immunity. Monoclonal antibodies, ustekinumab, golimumab, infliximab, guselkumab, Silkumab, adalimumab, rituximab, tocilizumab, centrizumab, centriz Mab pegol, sarilumab, secukinumab, ixekizumab, or their biosimilars (Versions, etc.) Etanercept, Abatacept, Anakinra, Epoetin Alpha, Darbepoetin alpha, epoetin beta-methoxypolyethylene glycol, Peguine Saturates, hormones, antitoxins, pain control substances, thrombosis control substances, infection control or elimination Substances, peptides, proteins, human insulin or human insulin analogs or derivatives Body, polysaccharides, DNA, RNA, enzymes, oligonucleotides, anti-allergic drugs, antihistamines Anti-inflammatory drugs, corticosteroids, disease-modifying antirheumatic drugs, erythropoietin, and This is a substance selected from a group consisting of vaccines.

[0174] 109. Using the system described in Embodiment 106, antibodies to human subjects (Monoclonal antibodies, ustekinumab, golimumab, infliximab, guselkumab) , silukumab, adalimumab, centrizumabrituximab, tocilizumab, centriz Mab, centrizumab pegol, sarilumab, secukinumab, ixekizumab, or these Biosimilar versions of (such as) etanercept, abatacept, anakinra, epoxidil Ethin alfa, darbepoetin alfa, epoetin beta-methoxypolyethylene Recall, peginesatide, hormones, antitoxins, pain control substances, thrombosis control substances, infection Substances for controlling or eliminating the disease, peptides, proteins, human insulin, or human insulin derivatives. Related compounds or derivatives, polysaccharides, DNA, RNA, enzymes, oligonucleotides, anti-allergens - Drugs, antihistamines, anti-inflammatory drugs, corticosteroids, disease-modifying antirheumatic drugs, erythrocytes Rheumatoid arthritis by delivery of a substance selected from the group consisting of thropoietin or vaccines. Psoriatic arthritis, ankylosing spondylitis, ulcerative colitis, hormone deficiency poisoning, pain, thrombosis, infection Infections, diabetes, diabetic retinopathy, acute coronary artery syndrome, angina pectoris, myocardial infarction, atherosclerosis Treatment for vascular sclerosis, cancer, macular degeneration, allergies, hay fever, inflammation, anemia, or myelodysplasia An injection device for use in treatment or prevention, or for the expression of protective immunity.

Claims

1. An accessory for an injection device having a needle cap, wherein the accessory is A main body portion having a recess adapted for receiving the injection device, A cover connected to the main body portion, wherein the cover has the recess exposed and the note An open position for receiving the injection device, and a position in which the recess is at least partially closed to allow the injection device to be placed in front of the recess. A closed position held by the main body and a cover that can pivot between these positions, A cap removal device comprising a gripping portion adapted to hold the aforementioned needle cap. The cap removal device is movable relative to the main body portion, and the cap removal The device includes, The aforementioned cover is The user moves the cover from the open position to the closed position. The proximal end is adapted to the shape, When the cover is moved from the open position to the closed position, the gripping portion is attached Move the accessory toward the end, and at least partially remove the needle cap from the injection device. An accessory comprising a distal end adapted for removal.

2. The cover is connected to the main body portion around at least one pivot point, claim 1 Accessories as listed.

3. The at least one pivot part is, The main body portion has at least one opening, At least one protrusion within the cover, wherein the at least one protrusion is front The attachment according to claim 2, comprising at least one projection that is rotatable within the opening. Accessories.

4. The cover extends distally from at least one pivot portion, and It also has a distal extension, and the distal end of the cover is at the end of the distal extension. The accessory provided according to claim 2 or 3.

5. The cover has a proximal extension that extends proximally away from the at least one pivot portion. An accessory according to any one of claims 2 to 4, comprising:

6. The distal extension is shorter than the proximal extension, as described in claims 4 and 5. 。

7. The distal end of the cover is the cap removal device slot of the cap removal device. An accessory according to any one of claims 1 to 6, comprising a cover cam disposed within a set.

8. To move the cap removal device within the accessory, the front of the pivot axis The rotation of the cover cam moves the cover cam against the slot of the cap removal device. The accessory described in claim 7, which is used to perform an action.

9. To move the cap removal device toward the distal end of the accessory, the cap The bar pivots from the open position to the closed position, and the cap removal device slot The attachment according to claim 7 or 8, which is arranged to act in opposition to the cover cam. Accessories.

10. The gripping portion is such that the cap removal device slot faces the distal end of the accessory. While moving, the needle cap is held and the needle cap is removed from the injection device. The accessory according to claim 9, which is arranged to be partially removable.

11. To move the cap removal device toward the proximal end of the accessory, the cap The bar pivots from the closed position to the open position, and the cap removal device slot Arranged to act in opposition to the cover cam, any one of claims 7 to 10 Accessories as described in item 1.

12. The cover is connected to the main body portion by a pair of pivots, according to claims 1 to 11. Any of the accessories listed in item 1.

13. Each of the pair of pivot parts has an opening in the main body and a protruding part inside the cover. The accessory according to claim 12, comprising the above, wherein the protruding portion is rotatable within the opening.

14. The cover extends distally from each of the pair of pivot parts. The accessory according to claim 12 or claim 13, comprising a pair of distal extensions.

15. The cover extends proximal to each of the pair of pivots. An accessory according to any one of claims 12 to 14, comprising a pair of proximal extensions.

16. Each distal extension is shorter than the corresponding proximal extension, as described in claims 14 and 15. Included accessories.

17. A pair of covers are provided at each of the ends of the distal extension. It further comprises distal ends, one of which of the distal ends is positioned in front of the cover from the open position. When moved to the closed position, the gripping portion moves toward the end of the accessory, To remove the needle cap from the injection device, remove the cap at least partially. Claim 14, which is operably connected to a detachment device, and optionally claim 15 and / or The accessory is as described in claim 16.

18. Each distal end of the cover is connected to the corresponding cap removal device of the cap removal device. The accessory according to claim 17, comprising a cover cam positioned within a removal device slot.

19. To move the cap removal device within the accessory, each of the pivot axes The rotation of the cover cam is opposed to the corresponding cap removal device slots. The accessory according to claim 18, which activates the cover cam.

20. To move the cap removal device toward the distal end of the accessory, the cap The bar pivots from the open position to the closed position, and the corresponding cap removal mechanism Arranged to cause each cover cam to act in opposition to the mounting slot, claim 18 or claim Accessories as described in item 19.

21. The gripping portion is such that the cap removal device slot faces the distal end of the accessory. While moving, hold the needle cap and remove the needle cap from the injection device. The accessory according to claim 20, which is arranged in such a manner.

22. To move the cap removal device toward the proximal end of the accessory, the cap The bar pivots from the closed position to the open position, and the corresponding cap removal mechanism The cover cams are arranged to act in opposition to the mounting slots, according to claims 18 to 21. Accessories listed in any one of the items.

23. A system for administering an injection, wherein the system comprises the needle having the needle cap. A system comprising a firing device and an accessory as described in any one of claims 1 to 22.

24. The injection device is Rheumatoid arthritis, psoriatic arthritis, ankylosing spondylitis, ulcerative colitis, hormone deficiency poisoning, pain Pain, thrombosis, infection, diabetes, diabetic retinopathy, acute coronary syndrome, angina pectoris, myocardial infarction, Atherosclerosis, cancer, macular degeneration, allergies, hay fever, inflammation, anemia, or Antibodies (mono) for use in the treatment or prevention of myelodysplasia, or for the expression of protective immunity. Clonal antibodies, ustekinumab, golimumab, infliximab, guselkumab, sil Kumab, adalimumab, rituximab, tocilizumab, centrizumab, centrizumab Pegol, sarilumab, secukinumab, ixekizumab, or biosimilar bars of these. John, et al., etanercept, abatacept, anakinra, epoetin alfa, dal Bepoetin alpha, epoetin beta-methoxypolyethylene glycol, Peginesati D, hormones, antitoxins, pain control substances, thrombosis control substances, substances for controlling or eliminating infections Proteins, peptides, proteins, human insulin or human insulin analogs or derivatives, Polysaccharides, DNA, RNA, enzymes, oligonucleotides, anti-allergic drugs, antihistamines , anti-inflammatory drugs, corticosteroids, disease-modifying antirheumatic drugs, erythropoietin, or The system according to claim 23, comprising a substance selected from the group consisting of cutin.

25. A substance, the delivery of the substance to a human subject using the system described in claim 23. This is done by the substance, which is used in rheumatoid arthritis, psoriatic arthritis, ankylosing spondylitis, and ulcerative colon. Inflammation, hormone deficiency poisoning, pain, thrombosis, infection, diabetes, diabetic retinopathy, acute coronary artery disease Syndrome, angina pectoris, myocardial infarction, atherosclerosis, cancer, macular degeneration, allergies, flowers For the treatment or prevention of pollen allergies, inflammation, anemia, or myelodysplasia, or for the development of protective immunity. Antibodies for use (monoclonal antibodies, ustekinumab, golimumab, inflix) Simab, guselkumab, silukumab, adalimumab, rituximab, tocilizumab, sen Tolizumab, centrizumab pegol, sarilumab, secukinumab, ixekizumab, or These biosimilar versions include etanercept, abatacept, and anakinra. , epoetin alpha, darbepoetin alpha, epoetin beta-methoxypolyethylene Lenglycol, peginesatide, hormones, antitoxins, pain control substances, thrombosis control substances , substances for controlling or eliminating infectious diseases, peptides, proteins, human insulin or human insulin Phosphorus analogs or derivatives, polysaccharides, DNA, RNA, enzymes, oligonucleotides, anti-phosphorus compounds Allergy medications, antihistamines, anti-inflammatory drugs, corticosteroids, disease-modifying antirheumatic drugs A substance selected from the group consisting of erythropoietin or vaccines.

26. By using the system described in claim 23, an antibody (monoclorose) can be applied to a human subject. Naru antibody, ustekinumab, golimumab, infliximab, guselkumab, silkumab Adalimumab, rituximab, tocilizumab, centrizumab, centrizumab pegol sarilumab, secukinumab, ixekizumab, or their biosimilar versions (etc.), etanercept, abatacept, anakinra, epoetin alpha, dalbepoe Chin alpha, epoetin beta-methoxypolyethylene glycol, peginesatide, ho Lumon, antitoxins, pain control substances, thrombosis control substances, infection control or elimination substances, Butides, proteins, human insulin or human insulin analogs or derivatives, polysaccharides DNA, RNA, enzymes, oligonucleotides, anti-allergic drugs, antihistamines, anti-inflammatory drugs Symptomatic drugs, corticosteroids, disease-modifying antirheumatic drugs, erythropoietin, or vaccines Delivery of a substance selected from the group consisting of the following is used to treat rheumatoid arthritis, psoriatic arthritis, and ankylosing spine. Inflammation, ulcerative colitis, hormone deficiency poisoning, pain, thrombosis, infection, diabetes, diabetic retina Coronary artery disease, acute coronary syndrome, angina pectoris, myocardial infarction, atherosclerosis, cancer, macular degeneration, For the treatment or prevention of allergies, hay fever, inflammation, anemia, or myelodysplasia, or for prevention An injection device used for inducing immunity.

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