Detergents and cleaning compositions having stabilized enzymes

Abstract

The present invention relates to enzyme detergents and cleaning compositions having improved enzyme stability, comprising specific enzyme stabilizers. More specifically, the present invention relates to detergents and cleaning compositions comprising an enzyme, an effective amount of a specific type of enzyme stabilizer, such as an alkanediol having a carbon chain of 5 to 14 carbon atoms, glyceryl caprylate, 4-hydroxyacetophenone, ethylhexylglycerin, tropolone, or a mixture of the aforementioned enzyme stabilizers, and a surfactant, as well as the use of the aforementioned detergents and cleaning compositions for preparing detergents and cleaning products for household, institutional, and industrial applications. In addition, the present invention relates to the use of specific enzyme stabilizers, as defined herein, for stabilizing enzymes in detergents and cleaning compositions. Furthermore, the present invention relates to a method for stabilizing enzymes in detergents and cleaning compositions by adding an effective amount of a specific type of enzyme stabilizer, such as an alkanediol having a carbon chain of 5 to 14 carbon atoms, glyceryl caprylate, 4-hydroxyacetophenone, ethylhexylglycerin, tropolone, or a mixture of the aforementioned enzyme stabilizers to the aforementioned detergents and cleaning compositions. Finally, the present invention relates to enzyme compositions comprising a specific type of enzyme stabilizer.

Description

[Technical Field]

[0001] The present invention generally relates to the field of detergents and cleaning compositions. In particular, it relates to enzyme detergents and cleaning compositions comprising specific hydroxyl compounds and having improved enzyme stability.

[0002] More specifically, the present invention relates to detergents and cleaning compositions comprising an enzyme, an effective amount of 1,2-heptanediol and / or 2,3-heptanediol or a specific type of enzyme stabilizer, such as an alkanediol having a carbon chain of 5 to 14 carbon atoms, glyceryl caprylate, 4-hydroxyacetophenone, ethylhexylglycerin, tropolone, or a mixture of the aforementioned enzyme stabilizers, and a surfactant, as well as the use of the aforementioned detergents and cleaning compositions for preparing detergents and cleaning products for household, institutional and industrial applications. In addition, the present invention relates to the use of specific enzyme stabilizers as defined herein for stabilizing enzymes in detergents and cleaning compositions. Finally, the present invention relates to a method for stabilizing enzymes in detergents and cleaning compositions by adding an effective amount of a specific enzyme stabilizer, such as an alkanediol having a carbon chain of 5 to 14 carbon atoms, glyceryl caprylate, 4-hydroxyacetophenone, ethylhexylglycerin, tropolone, or a mixture of the aforementioned enzyme stabilizers to the aforementioned detergents and cleaning compositions. [Background technology]

[0003] Detergents and cleaning compositions, particularly those for laundry and textile cleaning, dishwashing, etc., are mainly composed of surfactants or mixtures of surfactants, whose primary role is to remove dirt and water-insoluble substances such as grease from surfaces such as fabrics, clothing, dishes, and garments, as well as hard surfaces such as metals, plastics, glass, and ceramics. In addition to surfactants, modern detergents and cleaning formulations consist of builders, chelating agents, co-builders, other polymer additives used for specific cleaning or cleaning effects such as stain release and wrinkle prevention, color transfer prevention and rheological modification, as well as enzyme stabilizers. In addition to the aforementioned components, one or more enzymes are added to detergents and cleaning compositions as further active substances having a cleaning action.

[0004] Enzymes have been used in detergents and cleaning compositions since the early 20th century. Enzymes can be used to enhance the performance of cleaning or detergents. Enzymes are known as effective chemicals for breaking down dirt when used with detergents and other cleaning agents. They improve the cleaning of substrates by breaking down dirt, making them more soluble, and allowing surfactants to remove them from surfaces. Specifically, enzymes can provide desirable activity for removing protein-based, carbohydrate-based, or triglyceride-based stains from substrates, for example. As a result, enzymes have been used in a variety of cleaning applications to digest or break down dirt such as grease, oil (e.g., vegetable oil or animal fat), proteins, and carbohydrates. For example, enzymes can be added as components to compositions for fabric care, textile cleaning, dishwashing, stationary cleaning, drain cleaning, floor cleaning, carpet cleaning, medical or dental instrument cleaning, meat cutting tool cleaning, hard surface cleaning, and personal care.

[0005] However, the use of enzymes in such detergents and cleaning compositions has proven difficult due to stability issues.

[0006] Proteins and / or enzymes can be damaged during storage, for example, by inactivation, denaturation, or disintegration, for example, by physical effects, oxidation, or proteolytic cleavage.

[0007] The stability issues encountered worsen over time and under storage or transport conditions exceeding standard ambient temperature (25°C), particularly above 35°C.

[0008] Most enzymes used are sensitive to components contained in detergents and cleaning compositions, leading to a loss of enzymatic performance. Enzymes tend to be affected by surfactants and bleaching agents in the formulation. In addition, proteases also hydrolyze themselves (autoproteolysis) and all other proteins, especially enzymes. This occurs particularly during the washing process, i.e., in aqueous washing solutions, when relatively favorable reaction conditions are present. This also occurs during storage of the aforementioned compositions, and for this reason, extended storage times also involve some loss of protease activity and the activity of other enzymes. This is particularly problematic in gel-like or liquid and aqueous recipes, as the reaction medium and hydrolysis reagents are water.

[0009] In the past, many methods have been employed to improve the stabilization of enzymes for storage. For example, borate-based stabilization systems have been used in attempts to address the stability of enzyme preparations.

[0010] However, the use of the aforementioned stabilization systems has several drawbacks. Firstly, borate-containing compositions have been scrutinized, and regulations limiting their formulation have been proposed, potentially leading to their complete exclusion. Secondly, borate-based compositions have not provided the desired level of stability. Boric acid derivatives, regardless of their stabilizing effect, have significant drawbacks: many of these, such as borates, form undesirable by-products with other cleaning and / or detergent components, resulting in them being no longer available in the relevant agent for the desired purpose, or even remaining as impurities on the article being cleaned.

[0011] Other attempts to stabilize enzymes in detergents and cleaning compositions include the use of components such as amine oxides and / or alkyl polyglucosides, which have undesirable effects. These components are problematic because they are foaming. In particular, in many cleaning situations, including the cleaning of medical and dental instruments, there is a need to minimize foam in detergents and cleaning compositions so that the surface being cleaned remains visible.

[0012] Loss of enzyme performance in detergents and cleaning compositions results in a loss of cleaning performance.

[0013] The detergent and cleaning industry is in a perpetual search for ingredients that can solve these negative aspects.

[0014] Therefore, there is still a need for substances that have the ability to improve enzyme stability in detergents and cleaning compositions.

[0015] Therefore, the object of the present invention is to provide a multipurpose enzyme-containing detergent and cleaning composition that has excellent enzyme stability in the detergent and cleaning composition and thus has improved cleaning performance.

[0016] Furthermore, an object of the present invention is to provide enzyme-containing detergents and cleaning compositions that offer better enzyme stabilization compared to detergents and cleaning compositions containing conventional enzyme stabilizers.

[0017] Another object of the present invention is to provide a substance that can stabilize enzymes or enzyme mixtures in detergents and cleaning compositions.

[0018] Finally, another object of the present invention is to provide a method for stabilizing enzymes in detergents and cleaning compositions.

[0019] Finally, a further object of the present invention is to provide an enzyme composition comprising an enzyme and an enzyme stabilizer.

[0020] Surprisingly, it has been found that adding an effective amount of a specific type of enzyme stabilizer, such as an alkanediol having a carbon chain of 5 to 14 carbon atoms, glyceryl caprylate, 4-hydroxyacetophenone, ethylhexylglycerin, tropolone, or a mixture of the aforementioned enzyme stabilizers as defined herein, to detergents and cleaning compositions containing an enzyme or enzyme mixture has a positive effect on enzyme performance by significantly slowing the rate of enzyme inactivation by efficiently stabilizing the enzyme or enzyme mixture. The enzymes in these detergents and cleaning compositions exhibit excellent stability during storage and therefore maintain their performance over time. More specifically, the enzyme detergents and cleaning compositions exhibit stability after being stored for at least two weeks at temperatures above standard ambient temperature (25°C), particularly above 35°C.

[0021] In addition, based on the improved enzyme stability, the enzyme can function for a longer period and therefore provide higher cleaning efficacy by effectively removing dirt and / or stains.

[0022] Conversely, due to the excellent stability of the enzyme, the amount of other components such as enzymes and enzyme stabilizers used to enhance the effectiveness of the enzyme in these detergents and cleaning compositions can be reduced in order to achieve a similar cleaning effect, i.e., without losing cleaning performance. [Overview of the project]

[0023] This invention has been made in view of the above problems. To solve the above problems, this invention provides an enzyme-containing detergent and cleaning composition having improved enzyme stability.

[0024] To achieve the above objectives, the present invention, in a first aspect, provides a detergent and a cleaning composition, (a) at least one enzyme or an enzyme preparation comprising at least one enzyme; (b) (b I(a) At least one straight-chain alkanediol having a carbon chain of 5 to 14 carbon atoms, or at least one first straight-chain alkanediol having a carbon chain of 5 to 14 carbon atoms and one or more second straight-chain alkanediols having a carbon chain of 5 to 14 carbon atoms different from the first straight-chain alkanediol, in a mixture; (b II (b) Glyceryl caprylate; (b III (c) 4-Hydroxyacetophenone; (b IV (d) Ethylhexylglycerin; (b V (e) Tropolone; and At least one enzyme stabilizer selected from the group consisting of any mixtures thereof; (c) A surfactant in an amount of more than 3% by weight based on the total weight of the composition; and [[ID=2"](d) A detergent and cleaning composition comprising, or consisting of, at least one further enzyme stabilizer different from the enzyme stabilizer (b).

[0025] In particular, the present invention relates to a detergent and cleaning composition, (a) At least one enzyme or an enzyme preparation containing at least one enzyme; (b (b I (b) At least one straight-chain alkanediol having a carbon chain of 6 to 14 carbon atoms, or at least one first straight-chain alkanediol having a carbon chain of 5 to 14 carbon atoms and one or more second straight-chain alkanediols having a carbon chain of 5 to 14 carbon atoms different from the first straight-chain alkanediol, in a mixture; (b II (c) Glyceryl caprylate; (b III (d) 4-Hydroxyacetophenone; (b IV (e) Ethylhexylglycerin; (b V (f) Tropolone; and At least one enzyme stabilizer selected from the group consisting of any mixtures thereof; (c) surfactants in an amount exceeding 3% by weight based on the total weight of the composition; and (d) The present invention relates to detergents and cleaning compositions comprising or comprising at least one further enzyme stabilizer different from enzyme stabilizer (b).

[0026] In a further embodiment, the present invention provides the use of detergent and cleaning compositions as detergents and cleaning products, or for the preparation of detergents and cleaning products.

[0027] In a further embodiment, the present invention provides detergents and cleaning products.

[0028] In a further embodiment, the present invention relates to the use of at least one enzyme stabilizer, (b I ) A mixture comprising at least one linear alkanediol having a carbon chain of 5 to 14 carbon atoms, or at least one first linear alkanediol having a carbon chain of 5 to 14 carbon atoms and one or more second linear alkanediols having carbon chains of 5 to 14 carbon atoms different from the first linear alkanediol; (b II ) Glyceryl caprylate; (b III )4-hydroxyacetophenone; (b IV Ethylhexylglycerin; (b V ) Tropolone; and Selected from the group consisting of any mixture thereof; This invention provides a use for stabilizing enzymes in detergents and cleaning compositions.

[0029] In another embodiment, the present invention relates to a method for stabilizing enzymes in detergents and cleaning compositions, (i) A step of providing a detergent and cleaning composition containing an enzyme; (ii) (b I) A mixture comprising at least one linear alkanediol having a carbon chain of 5 to 14 carbon atoms, or at least one first linear alkanediol having a carbon chain of 5 to 14 carbon atoms and one or more second linear alkanediols having carbon chains of 5 to 14 carbon atoms different from the first linear alkanediol; (b II ) Glyceryl caprylate; (b III )4-hydroxyacetophenone; (b IV Ethylhexylglycerin; (b V ) Tropolone; and The present invention provides a method comprising the step of adding an effective amount of at least one enzyme stabilizer selected from the group consisting of any mixtures thereof.

[0030] In the final aspect, the present invention relates to an enzyme composition, (A) at least one enzyme; (B) (B I A mixture comprising at least one first linear alkanediol having a carbon chain of 5 to 14 carbon atoms, and one or more second linear alkanediols having a carbon chain of 5 to 14 carbon atoms different from that of the first linear alkanediol; (B II ) Glyceryl caprylate; (B III )4-hydroxyacetophenone; (B IV Ethylhexylglycerin; (B V ) Tropolone; and At least one enzyme stabilizer selected from the group consisting of any mixture thereof; and (C) The present invention provides an enzyme composition comprising or comprising at least one further enzyme stabilizer different from enzyme stabilizer (B).

[0031] The present invention is defined in the appended claims. However, the invention itself, preferred variations thereof, other purposes and advantages are also evident from the following detailed description in conjunction with the appended examples and drawings.

[0032] All percentages are by weight unless otherwise specified.

[0033] Numerical ranges listed herein and given in the form "x~y" include the value that defines the range and each integer within the defined range. If multiple preferred numerical ranges are specified in this form, all ranges created by combining various endpoints are also included.

[0034] In the context of this invention, the term "comprising" means that the specified components are essential, but other components may be added and still be included in this invention.

[0035] The term "consisting of" as used in accordance with the present invention means that the total amount of components (a) to (d) in the composition totals 100% by weight based on the total weight of the composition, and that the subject matter is closed-ended and may only include the explicitly listed limitations.

[0036] Whenever the word "comprising" is used, it is intended to encompass both meanings as alternatives; that is, unless the context otherwise indicates, the meaning can be either "comprising" or "consisting of."

[0037] In the context of the present invention, the term "at least one" means that the detergents and cleaning compositions according to the present invention may contain one or a mixture of two, three, four, five, six or more different components from those following the aforementioned terms.

[0038] The terms "and / or" indicate that a combination exists or that an alternative is provided.

[0039] The term "optional" means that the following components may, but are not required to, be present in the detergent and cleaning composition, and that the description includes variants containing the compound or variants in which the compound is not present.

[0040] In the context of this invention, the term "stability" means resistance or degree of resistance to change, unfolding, disintegration, denaturation, or loss of activity. A non-limiting example of stability is storage stability, which reflects the stability of polypeptides such as enzymes as a function of time, and reflects, for example, the degree to which the performance of the aforementioned polypeptide is retained when it is held in a detergent or cleaning formulation. Stability is influenced by many factors, such as the presence of chelating agents, pH, temperature, and the detergent composition, such as the amount of builders and surfactants.

[0041] In the context of this invention, the term “boosting” means “improvement,” “enhancement,” or “increase.” Correspondingly, “boosting” is either a single agent or a mixture of agents that can “improve,” “enhance,” or “increase” certain features or properties as defined herein, particularly the stability of enzymes in the detergents and cleaning compositions according to the present invention. Certain enzyme stability can provide consistent cleaning power in the detergents and cleaning compositions.

[0042] As used herein, the term "alkyl" refers to saturated hydrocarbons having one or more carbon atoms, including linear alkyl groups (e.g., methyl, ethyl, propyl, butyl, pentyl, hexyl, heptyl, octyl, nonyl, decyl, undecyl, dodecyl, tridecyl, tetradecyl, pentadecyl, hexadecyl, heptadecyl, octadecyl, etc.), cyclic alkyl groups (or cycloalkyl, alicyclic, or carbocyclic groups) (e.g., cyclopropyl, cyclopentyl, cyclohexyl, cycloheptyl, cyclooctyl, etc.), branched alkyl groups (e.g., isopropyl, tert-butyl, sec-butyl, isobutyl, etc.), and alkyl-substituted alkyl groups (e.g., cycloalkyl-substituted alkyl groups).

[0043] Unless otherwise specified, the term "alkyl" includes both unsubstituted alkyls and substituted alkyls. As used herein, the term "substituted alkyl" refers to an alkyl group having substituents that substitute one or more hydrogens on one or more carbons of a hydrocarbon skeleton. Examples of such substituents include alkenyls, alkynyls, halogens, hydroxyls, alkylcarbonyloxys, arylcarbonyloxys, alkoxycarbonyloxys, aryloxycarbonyloxys, carboxylates, alkylcarbonyls, arylcarbonyls, alkoxycarbonyls, aminocarbonyls, alkylaminocarbonyls, dialkylaminocarbonyls, alkylthiocarbonyls, alkoxyls, phosphates, phosphonates, cyanos, aminos, iminos, sulfhydryls, alkylthios, arylthiols, thiocarboxylates, sulfates, alkylsulfinyls, sulfonates, and nitros. [Modes for carrying out the invention]

[0044] In a first aspect, the present invention relates to detergents and cleaning compositions, (a1) At least one enzyme or an enzyme preparation comprising at least one enzyme; (b1) 1,2-heptanediol; (c1) Surfactants exceeding 3% by weight based on the total weight of the composition; and (d1) The present invention relates to detergents and cleaning compositions comprising or comprising at least one further enzyme stabilizer.

[0045] Alternatively, in a first aspect of the present invention, the present invention relates to a detergent and a cleaning composition, (a2) At least one enzyme or an enzyme preparation comprising at least one enzyme; (b2) 2,3-heptanediol; (c2) Surfactants exceeding 3% by weight based on the total weight of the composition; and (d2) The present invention relates to detergents and cleaning compositions comprising or comprising at least one further enzyme stabilizer.

[0046] In a further alternative, the present invention, in a first aspect, is a detergent and a cleaning composition, (a3) At least one enzyme or an enzyme preparation comprising at least one enzyme; (b3) A mixture containing 1,2-heptanediol and 2,3-heptanediol; (c3) Surfactants exceeding 3% by weight based on the total weight of the composition; and (d3) The present invention relates to detergents and cleaning compositions comprising or comprising at least one further enzyme stabilizer.

[0047] Alternatively, in another embodiment, the present invention relates to detergents and cleaning compositions, (a) at least one enzyme or an enzyme preparation comprising at least one enzyme; (b) (b I ) A mixture comprising at least one linear alkanediol having a carbon chain of 5 to 14 carbon atoms, or at least one first linear alkanediol having a carbon chain of 5 to 14 carbon atoms and one or more second linear alkanediols having carbon chains of 5 to 14 carbon atoms different from the first linear alkanediol; (b II ) Glyceryl caprylate; (b III )4-hydroxyacetophenone; (b IV Ethylhexylglycerin; (b V ) Tropolone; and At least one enzyme stabilizer selected from the group consisting of any mixture thereof; (c) surfactants in an amount exceeding 3% by weight based on the total weight of the composition; and (d) The present invention relates to detergents and cleaning compositions comprising or comprising at least one further enzyme stabilizer different from enzyme stabilizer (b).

[0048] In particular, the present invention relates to detergents and cleaning compositions, (a) at least one enzyme or an enzyme preparation comprising at least one enzyme; (b) (b I A mixture comprising at least one linear alkanediol having a carbon chain of 6 to 14 carbon atoms, or at least one first linear alkanediol having a carbon chain of 5 to 14 carbon atoms, and one or more second linear alkanediols having carbon chains of 5 to 14 carbon atoms different from the first linear alkanediol; (b II ) Glyceryl caprylate; (b III )4-hydroxyacetophenone; (b IV Ethylhexylglycerin; (b V ) Tropolone; and At least one enzyme stabilizer selected from the group consisting of any mixture thereof; (b) surfactants in an amount greater than 3% by weight based on the total weight of the composition; and (c) The present invention relates to detergents and cleaning compositions comprising or comprising at least one further enzyme stabilizer different from enzyme stabilizer (b).

[0049] In a more preferable variation, at least one linear alkanediol in the detergent and cleaning composition according to the present invention has a carbon chain length of 7 to 12 carbon atoms, more preferably 7 to 11 carbon atoms, even more preferably 7 to 10 carbon atoms, and most preferably 7 to 9 carbon atoms. Most preferably, the linear alkanediol in the detergent and cleaning composition has a carbon chain length of 7 or 8 carbon atoms.

[0050] The term “detergents and cleaning compositions” as intended herein is understood to mean all products that are suitable for cleaning or washing and are commonly used. Detergents and cleaning compositions consist primarily of surfactants or mixtures of surfactants. In addition to surfactants, detergents and cleaning compositions typically consist of builders and chelators, cobuilders, and other polymer additives used for specific effects such as stain release, wrinkle prevention, color transfer prevention, and rheological modification. Detergents and cleaning compositions refer to compositions used to remove undesirable compounds from items to be cleaned, such as textiles (e.g., fabrics, clothing), dishes, floors, and hard surfaces (e.g., metals, plastics, and ceramics). These deposits can be caused by dirt or stains, bacteria, and other contaminants. Detergents are the most commonly used cleaning compositions for textiles. Detergents and cleaning compositions may be used for both household cleaning, facility cleaning, and industrial cleaning. Detergents and cleaning compositions also contain bactericides that kill all vegetative cells, including recognized pathogenic microorganisms. Detergents and cleaning compositions may be used by the detergent composition itself, by detergent products, or by their solutions.

[0051] Detergents and cleaning compositions according to the first and second embodiments of the present invention are preferably used to remove stains and / or dirt from textiles, fabrics, laundry, dishes, clothing, medical and dental instruments, hard surfaces, and the like.

[0052] Within the scope of the present invention, the terms “cleaning” and “washing” are used synonymously and refer to the reduction and / or removal of deposits, i.e., the removal of undesirable compounds from items being washed, such as tableware / dishes and other kitchenware, e.g., cutlery / silverware, pots, pans, bakeware, etc.

[0053] These deposits can be formed by stains caused by tea, chocolate, coffee, grass, red wine, grass / mud, fruit juice, blood, tomato puree, unused motor oil, balsamic salad dressing, cooked beef tallow, French squeeze mustard, makeup, etc., or by stains caused by grease, starch-based stains such as rice, pasta, protein-based stains such as egg yolk, chocolate, mayonnaise, lipstick starch-based stains, etc., and other stains remaining on the surface. Thus, deposits are any form of undesirable residue such as dirt, grime, food, and grease.

[0054] In the context of the present invention, the term “substrate” includes fabrics, textiles, laundry, dishes, clothing, any hard surface, medical and dental instruments, etc., which may be contaminated with dyes and / or stains and may be treated by washing or a washing process.

[0055] As used herein, the term “fabric cleaning” includes detergents and cleaning compositions or products designed for cleaning dyed and / or soiled materials. Such compositions or products include, but are not limited to, laundry detergent compositions, fabric softening compositions, fabric strengthening compositions, fabric freshening compositions, pre-washes, pre-wash treatments, laundry additives, spray products, dry cleaning agents or compositions, wash rinse additives, cleaning additives, post-rinse fabric treatments, ironing aids, unit-dose formulations, delayed-delivery formulations, detergents contained on or in porous substrates or nonwoven sheets, fibrous substrates, preferably the aforementioned fibers containing activators, and other suitable forms that may be apparent to those skilled in the art.

[0056] As used herein, the term “fabric care” refers to a variety of fabric benefits, including smoothness, shape retention, elasticity, color preservation, and pilling control.

[0057] As used herein, the terms “dishware” or “ware” refer to solid surfaces such as countertops, tiles, floors, walls, panels, windows, plumbing, kitchen and bathroom furniture, appliances, engines, circuit boards, and tableware. Examples of hard surfaces include healthcare surfaces such as medical or dental instruments, medical or dental devices, electronic devices used to monitor patient health, and the surfaces of floors, walls, or fixtures in structures where healthcare is performed, as well as food processing surfaces such as the surfaces of tools, machines, equipment, and structures used as part of food processing, preparation, or storage activities. In the context of the present invention, the term “ware” refers to items such as eating and cooking utensils, tableware, and other hard surfaces such as showers, sinks, toilet bathtubs, countertops, windows, mirrors, and floors.

[0058] As used herein, the term “surface” refers to solid surfaces such as countertops, tiles, floors, walls, panels, windows, plumbing, kitchen and bathroom furniture, appliances, engines, circuit boards, and tableware. Examples of hard surfaces include healthcare surfaces such as medical or dental instruments, medical or dental devices, electronic devices used to monitor patient health, and the surfaces of floors, walls, or fixtures in structures where healthcare is performed, as well as food processing surfaces such as the surfaces of tools, machinery, equipment, and structures used as part of food processing, preparation, or storage activities.

[0059] As used herein, “enzyme stabilizer” (b) is a substance that stabilizes enzymes in detergents and cleaning compositions at temperatures above standard ambient temperature (25°C), particularly above 35°C, for at least two weeks during storage. The aforementioned agents are generally known in the art and are different from “additional enzyme stabilizers” (d) used in addition to enzyme stabilizers to provide further enzyme stabilization effects.

[0060] Surprisingly, it has been found that the addition of enzyme stabilizers specified herein or mixtures of the aforementioned enzyme stabilizers to detergents and cleaning compositions stabilizes the enzymes in the detergents and cleaning compositions during storage. In this way, the enzyme performance, and therefore the cleaning performance, of such detergents and cleaning compositions can be kept stable.

[0061] Based on these advantageous effects, the detergents and cleaning compositions according to the present invention provide both enzyme stability during storage for at least two weeks and at temperatures above standard ambient temperature (25°C), particularly above 35°C, as well as improved cleaning performance.

[0062] Enzymes or enzyme preparations / components (a1, a2, a3, a) The enzyme detergent and cleaning composition according to the present invention includes at least one enzyme, or an enzyme preparation containing at least one enzyme, as components (a1, a2, a3, a) that provide cleaning performance by removing dyes and / or stains, and / or fabric care effects.

[0063] Enzymes are known as chemicals that are effective in breaking down dirt when used with detergents and other cleaning agents. Enzymes improve the cleaning of substrates by breaking down dirt, making them more soluble, and allowing surfactants to remove them from the surface. Specifically, enzymes can provide desirable activity for removing, for example, protein-based, carbohydrate-based, or triglyceride-based stains from substrates. In addition, enzymes also help improve cleaning results at lower temperatures. As a result, enzymes have been used in a variety of cleaning applications to digest or break down dirt such as grease, oil (e.g., vegetable oil or animal fat), proteins, and carbohydrates. For example, enzymes can be added as components to compositions for laundry, textiles, dishwashing, stationary cleaning, drain cleaning, floors, carpets, medical or dental instruments, meat cutting tools, hard surfaces, and personal care.

[0064] Enzymes suitable for detergents and cleaning compositions may act by breaking down or altering one or more types of dirt residue encountered on an instrument or device, thereby removing the dirt, or by making the dirt more easily removed by the surfactant or other components of the cleaning composition. Both the breakdown and alteration of dirt residue can improve cleaning power by reducing the physicochemical forces binding the dirt to the instrument or device being cleaned, for example, making the dirt more water-soluble. For example, one or more proteases can cleave complex high-molecular-weight protein structures present in the dirt residue into simpler short-chain molecules, which in turn are more easily desorbed or solubilized from the surface, or otherwise more easily removed by a cleaning solution containing the aforementioned proteases.

[0065] The cleaning enzyme according to the present invention, as a component of detergents and cleaning compositions, has cleaning, decolorizing, stain removal, or other beneficial effects, and is for instruments, devices, or apparatus, such as medical or dental instruments or apparatus; or for laundry, textiles, clothing cleaning, stationary cleaning, drain pipes, carpets, meat cutting tools, hard surfaces, personal care, etc.

[0066] Enzymes that can be used in detergents and cleaning compositions according to the present invention include enzymes that provide desirable activity for removing protein-based, carbohydrate-based, or lipid-based (fat or oil-based) stains and / or stains from substrates; for washing, decolorizing, stain removal, disinfection soaking, for example, for soaking medical and dental instruments, devices, and apparatus; for soaking flatware, cookware, and tableware; or for soaking meat cutting apparatus; for washing machineware; for washing and washing and decolorizing laundry and textiles; for washing and decolorizing carpets; for cleaning in-place (CIP) and in-place decolorization; for washing and decolorizing food processing surfaces and equipment; for drain cleaning; and for soaking for washing.

[0067] Suitable enzymes to be used according to the first and second aspects of the present invention are selected from the group consisting of proteases, amylases, lipases, cellulases, cutinases, gluconases, peroxidases, pectinases, mannanases, esterases, hemicellulases, xylanases, phospholipases, pectinate lyases, keratinases, reductases, nucleases (including DNase and / or Rnase), phenol oxidases, lipoxygenases, ligninases, pullulanases, tannases, pentosanases, maranases, β-glucanases, arabinosidases, hyaluronidases, chondroitinases, oxidoreductases, and any mixtures thereof.

[0068] More preferably, the enzyme in the detergent and cleaning composition according to the present invention is selected from the group consisting of protease, amylase, lipase, cellulase, mannanase, pectinate lyase, and any mixture thereof.

[0069] The enzymes used in accordance with the present invention may be of any suitable origin, such as from plants, animals, bacteria, fungi, or yeast.

[0070] Proteases: Any protease or protease mixture from any source can be used in detergents and cleaning compositions, provided that the selected enzyme is stable within the desired pH range (approximately 6 to 9). For example, protease enzymes may be derived from plants, animals, or microorganisms such as yeast, mold, or bacteria. Preferred protease enzymes include, but are not limited to, those derived from Bacillus subtilis, Bacillus licheniformis, and Streptomyces griseus. Protease enzymes derived from Bacillus subtilis are most preferred. Proteases can be purified or be components of microbial extracts, and may be either wild-type or mutant (either chemically or recombinantly). Exemplary proteases are available from Novozymes under the trade names Alcalase®, Blaze®, Savinase®, Esperase®, Progress UNO®, Liquanase®, and Pristine®, respectively; and are also commercially available from DuPont / IFF under the trade names Preferred® P and Excellent® P.

[0071] Amylase: Any amylase or amylase mixture from any source can be used in detergents and cleaning compositions, provided that the selected enzyme is stable within the desired pH range (approximately 6 to 9). For example, the amylase enzyme may be derived from plants, animals, or microorganisms such as yeast, mold, or bacteria. Preferred amylase enzymes include, but are not limited to, Bacillus, e.g., Bacillus licheniformis, Bacillus amyloliquefaciens, Bacillus subtilis, and Bacillus stearothermophilus. The amylase enzyme derived from Bacillus subtilis is most preferred. The amylase may be purified or be a component of a microbial extract, and may be either wild-type or mutant (either chemical or recombinant). Preferred amylases are commercially available under the trade names Stainzyme® and Amplify® from Novozymes, and Preferredz® S from DuPont / IFF.

[0072] Lipase: Any lipase or lipase mixture from any source can be used in detergents and cleaning compositions, provided that the selected enzyme is stable within the desired pH range (approximately 6 to 9). For example, lipase enzymes may be derived from plants, animals, or microorganisms such as fungi or bacteria. Preferred protease enzymes include, but are not limited to, those derived from Pseudomonas, e.g., Pseudomonas stutzeri ATCC 19.154, or Humicola, e.g., Humicola lanuginosa (typically produced recombinantly in Aspergillus oryzae). Lipase can be purified or be a component of a microbial extract, and may be either wild-type or mutant (either chemically or recombinantly). Preferred lipases are available from Novozymes under the trade names Lipex® and Preferenz® L from DuPont / IFF.

[0073] Cellulase: Any cellulase or cellulase mixture from any source can be used in detergents and cleaning compositions, provided that the selected enzyme is stable within the desired pH range (approximately 6 to 9). For example, the cellulase enzyme may be derived from plants, animals, or microorganisms such as fungi or bacteria. Preferred cellulase enzymes include, but are not limited to, those derived from Humicola insolens, Humicola strain DSM1800, or cellulase 212-producing fungi belonging to the genus Aeromonas, and those extracted from the hepatopancreas of the marine mollusk Dolabella Auricula Solander. The cellulase may be purified or be a component of a microbial extract, and may be either wild-type or mutant (either chemically or recombinant). Preferred cellulases are commercially available under the trade names Celluclean® and Carezyme® from Novozymes, and Revitalez® from DuPont / IFF, respectively.

[0074] The choice of enzyme depends on the end-use conditions, including the physical product form, pH of use, temperature of use, and the type of dirt to be decomposed or modified, and is influenced by factors such as pH activity and / or optimal stability, thermal stability, and stability against active detergents, builders, etc. Enzymes may be selected to provide optimal activity and stability for any given set of practical conditions. In this regard, bacterial or fungal enzymes are preferred.

[0075] Protease enzymes, amylase enzymes, and lipase enzymes are the most commonly used enzymes in detergents and cleaning compositions. Protease enzymes are particularly advantageous for cleaning stains containing proteins, such as egg, milk, and meat residues. Amylase enzymes are particularly advantageous for removing starch-based stains such as pasta and rice. Lipase enzymes are particularly advantageous for cleaning stains containing fat / grease.

[0076] As those skilled in the art will understand, enzymes are designed to act on specific types of stains. For example, according to one embodiment of the present invention, a protease enzyme may be used for dishwashing applications because it is effective at the high temperatures of a dishwasher and is effective in reducing protein-based stains. Protease enzymes are particularly advantageous for cleaning protein-containing stains such as blood, skin scales, mucus, grass, and food (e.g., eggs, milk, spinach, meat residue, tomato sauce).

[0077] According to the present invention, the enzyme composition may vary based on a specific cleaning application and the type of dirt to be cleaned. For example, the temperature of a particular cleaning application affects the enzyme selected for the enzyme composition according to the present invention. For dishwashing applications, e.g., cleaning substrates at temperatures above about 60°C, above about 70°C, or between about 65°C and 80°C, enzymes such as proteases are desirable due to their ability to maintain enzymatic performance at such high temperatures. For laundry applications, e.g., cleaning laundry at temperatures above about 40°C, above about 50°C, or between about 65°C and 90°C, enzymes such as proteases are desirable due to their ability to maintain enzymatic performance at such high temperatures.

[0078] Preferably, at least one enzyme in the detergent and cleaning composition is selected from the group consisting of protease, amylase, lipase, gluconase, cellulase, peroxidase, or a mixture thereof.

[0079] In some variations, the enzymes in the detergent and cleaning composition are proteases, amylases, lipases, cellulases, gluconases, peroxidases, mannanases, or any mixture thereof.

[0080] Preferably, the enzymes in the detergent and cleaning composition are a mixture of protease, amylase, lipase, cellulase and / or pectinate lyase.

[0081] Preferred cleaning enzymes in detergents and cleaning compositions include hydrolases such as proteases, amylases, lipases, or combinations thereof.

[0082] Preferably, the enzymes in the detergent and cleaning composition are protease, amylase, lipase, cellulose, peroxidase, gluconase, or any mixture thereof.

[0083] In a more preferred variation, the enzymes in the detergents and cleaning compositions disclosed herein are proteases, amylases, lipases, or any mixture thereof.

[0084] More preferably, the enzyme in the detergent and cleaning composition is a protease, amylase, or a mixture thereof.

[0085] More preferably, the enzyme in the detergent and cleaning composition is a protease, lipase, or a mixture thereof.

[0086] More preferably, the enzyme in the detergent and cleaning composition is selected from amylase, lipase, or a mixture thereof.

[0087] In some other embodiments, the enzyme in the detergent and cleaning composition is a protease.

[0088] In several other variations, the enzyme in detergents and cleaning compositions is amylase.

[0089] In several other variations, the enzyme in the detergent and cleaning composition is lipase.

[0090] In several other variations, the enzyme in the detergent and cleaning composition is cellulase.

[0091] Preferred enzymes in the detergents and cleaning compositions according to the present invention for cleaning medical or dental devices or instruments include proteases, amylases, cellulases, lipases, or combinations thereof.

[0092] Preferred enzymes in the detergents and cleaning compositions according to the present invention for food processing surfaces and equipment include proteases, lipases, amylases, gluconases, or combinations thereof.

[0093] Preferred enzymes in the detergents and compositions according to the present invention for laundry or textiles include proteases, cellulases, lipases, peroxidases, or combinations thereof.

[0094] Preferred enzymes in carpet detergents and compositions include proteases, amylases, or combinations thereof.

[0095] Preferred enzymes in the detergent and cleaning composition according to the present invention for meat cutting tools include proteases, lipases, or combinations thereof.

[0096] Preferred enzymes in the detergent and cleaning composition according to the present invention for hard surfaces include proteases, amylases, lipases, or combinations thereof.

[0097] Preferred enzymes in the detergent and cleaning composition according to the present invention for wastewater use include proteases, amylases, lipases, or combinations thereof.

[0098] In the case of stain removers, the enzyme is preferably selected from the group consisting of proteases, amylases, lipases, mannanases, and pectin lyases.

[0099] For fabric softeners, the enzyme is preferably cellulase.

[0100] To enhance the bleaching effect, oxidoreductase is optionally added to the detergent and cleaning composition according to the first and second embodiments of the present invention.

[0101] Oxidoreductase is selected from the group consisting of oxidases, oxygenases, catalases, peroxidases such as halo-, chloro-, bromo-, lignin-, glucose-, or manganese-peroxidases, dioxygenases, or laccases such as phenol oxidases and polyphenol oxidases, and any mixture thereof.

[0102] Commercially available enzymes are available in liquid or dry form (i.e., packs, powders, etc.) and are sold as raw material aqueous solutions or in various purified, processed, and formulated forms established in the prior art, generally containing about 0.1% to about 80% by weight of active enzymes in combination with stabilizers, buffers, cofactors, impurities, and inactive vehicles. Assuming that detergents and cleaning compositions have the desired enzymatic performance, the actual active enzyme content is not important and depends on the manufacturing method.

[0103] This includes, for example, solid enzyme preparations obtained by granulation, extrusion, or freeze-drying, or, particularly in the case of liquid or gel-like drugs, enzyme solutions that are advantageously as concentrated as possible, low in moisture, and / or containing added stabilizers. Alternatively, for both solid and liquid dosage forms, enzymes can be encapsulated, for example, by spray-drying or extruding the enzyme solution together with a natural polymer, or in the form of capsules, for example, with the enzyme enclosed in a coagulated gel, or in a core-shell type where the enzyme-containing core is coated with a protective layer that is impermeable to water, air, and / or chemicals. Further active substances, such as stabilizers, emulsifiers, pigments, bleaches, or dyes, may be applied to the superimposed layers. Such capsules are applied using methods known to themselves, for example, by vibration granulation or roll granulation, or by fluidized bed granulation. Advantageously, such granules are low in dust, for example, as a result of the application of polymer film-forming agents, and have storage stability due to the coating. Furthermore, it is possible to package two or more enzymes together so that a single granule exhibits multiple enzyme properties.

[0104] In the modification according to the present invention, the enzyme is added to the detergent and cleaning composition as a single enzyme.

[0105] In some other variations, the enzymes added to the detergent and cleaning composition are preferably an enzyme cocktail of two, three, four, or even more different enzymes. Typically, in the case of laundry detergents, the enzyme cocktail contains two (preferably proteases and amylases) to six enzymes. In the case of dishwashing detergents, a typical enzyme cocktail contains two enzymes (preferably proteases and amylases).

[0106] More preferably, the enzyme is mixed with an enzyme stabilizer, preferably in combination with one or more enzyme stabilizers (b1, b2, b3, b) as defined herein, and / or with one or more commonly used enzyme stabilizers such as the enzyme stabilizers (d1, d2, d3, d) described below, optionally a buffer, etc., to be added to detergents and cleaning compositions as an enzyme preparation.

[0107] Preferred combinations of enzymes with specific types of enzyme stabilizers (b), such as alkanediols having carbon chains of 5 to 14 carbon atoms, glyceryl caprylates, 4-hydroxyacetophenone, ethylhexylglycerin, tropolone, or mixtures of the aforementioned enzyme stabilizers, are described in detail below.

[0108] Enzyme stabilizers / components (b1, b2, b3, b) The enzyme detergent and cleaning composition according to the present invention further comprises at least one enzyme stabilizer as component (b1, b2, b3, b).

[0109] In a preferred variation, the enzyme detergent and cleaning composition according to the present invention comprises a mixture of enzyme stabilizers.

[0110] An enzyme stabilizer within the scope of the present invention is (b I (b) A mixture comprising at least one linear alkanediol having a carbon chain of 5 to 14 carbon atoms, or at least one first linear alkanediol having a carbon chain of 5 to 14 carbon atoms and one or more second linear alkanediols having a carbon chain of 5 to 14 carbon atoms different from the first linear alkanediol; (b) II ) Glyceryl caprylate; (b III )4-hydroxyacetophenone; (b IV ) Ethylhexylglycerin; (b V ) Tropolone; and any mixture of the aforementioned enzyme stabilizers.

[0111] The aforementioned enzyme stabilizers have been found to efficiently stabilize enzymes in detergents and cleaning compositions, and therefore to slow down the rate of enzyme inactivation during storage. In this way, the cleaning performance of detergents and cleaning compositions is maintained over time.

[0112] Alkanediol (b1, b2, b3, b I ) Component (b) in the enzyme detergent and cleaning composition according to the first aspect of the present invention is a mixture containing either 1,2-heptanediol (b1) or 2,3-heptanediol (b2), or both, i.e., 1,2-heptanediol + 2,3-heptanediol (b3).

[0113] 1,2-Heptanediol belongs to the category of alkanediols and is a linear alkanediol with the general formula:

[0114] [ka] It has a carbon chain with seven carbon atoms, and the two functional OH groups of the alkanediol are located at the alpha and beta positions, chemically bonded to the C1 and C2 carbon atoms in the alkanediol chain.

[0115] 2,3-Heptanediol belongs to the category of alkanediols and is a linear alkanediol with the general formula:

[0116] [ka] It has a carbon chain with seven carbon atoms, and the two functional OH groups of the alkanediol are located in the beta and gamma positions, chemically bonded to the C2 and C3 carbon atoms in the alkanediol chain.

[0117] Alternatively, the enzyme stabilizing component (b) in the detergent and cleaning composition according to another aspect of the present invention is (b I ) Selected from the group consisting of at least one linear alkanediol having a carbon chain of 5 to 14 carbon atoms, or a mixture comprising at least one first linear alkanediol having a carbon chain of 5 to 14 carbon atoms and one or more second linear alkanediols having a carbon chain of 5 to 14 carbon atoms different from the first linear alkanediol.

[0118] Alkanediols are a class of organic compounds belonging to the glycol family, i.e., the alcohol family, in which two hydroxyl (-OH) groups are bonded to different carbon atoms in the carbon chain of a glycol molecule.

[0119] Straight-chain 1,2-alkanediols have been used as multifunctional surfactants for over 15 years. Short-chain 1,2-alkanediols are amphiphilic compounds and are therefore soluble in both water and oil, as are 1,2-pentanediol, 1,2-hexanediol, and 1,2-heptanediol. In contrast, 1,2-octanediol is a solid and tends to precipitate or recrystallize in oily solutions and water at ≥0.5% concentrations. On the other hand, 1,2-decanediol is a solid and soluble only in oil. Apart from moisturizing, some 1,2-alkanediols are used as viscosity modifiers.

[0120] The enzyme stabilizer (b) of detergents and cleaning compositions according to another aspect of the present invention is, in the first option, at least one linear alkanediol having a carbon chain of 5 to 14 carbon atoms.

[0121] Preferably, at least one linear alkanediol has a carbon chain of 6 to 14 carbon atoms.

[0122] More preferably, the linear alkanediol has a carbon chain of 7 to 14 carbon atoms, more preferably 7 to 12 carbon atoms, even more preferably 7 to 11 carbon atoms, and even more preferably 7 to 10 carbon atoms. Most preferably, at least one linear alkanediol has a carbon chain of 7 to 9 carbon atoms. Most preferably, at least one linear alkanediol has a carbon chain of 7 or 8 carbon atoms.

[0123] Furthermore, in a second alternative of this other embodiment, the enzyme stabilizing component (b) is a first linear alkanediol in combination with a second linear alkanediol, preferably a carbon chain of 5 to 14 carbon atoms (preferably a carbon chain of 6 to 14 carbon atoms, more preferably a carbon chain of 7 to 14 carbon atoms, more preferably a carbon chain of 7 to 12 carbon atoms, even more preferably a carbon chain of 7 to 11 carbon atoms, even more preferably a carbon chain of 7 to 10 carbon atoms, most preferably a carbon chain of 7 to 9 carbon atoms, most preferably 7 or 8 carbon atoms). The present invention may also comprise at least one first linear alkanediol having a carbon chain of atoms, and at least one second linear alkanediol having a carbon chain of 5 to 14 carbon atoms (preferably a carbon chain of 6 to 14 carbon atoms, more preferably a carbon chain of 7 to 14 carbon atoms, more preferably a carbon chain of 7 to 12 carbon atoms, even more preferably a carbon chain of 7 to 11 carbon atoms, even more preferably a carbon chain of 7 to 10 carbon atoms, most preferably a carbon chain of 7 to 9 carbon atoms, most preferably a carbon chain of 7 or 8 carbon atoms). Accordingly, the present invention also comprises a mixture comprising the first and second alkanediols described herein.

[0124] Since the first linear alkanediol of the present invention can be selected from the same list and type of compounds as the first alternative linear alkanediol in other embodiments, the following refers to linear alkanediols in general, which may also be the first linear alkanediol. In mixtures of the first and second linear alkanediols, where they are specifically different, the terms "first" and "second" are used to distinguish the two alkanediol components.

[0125] As used herein, the phrases “at least one linear alkanediol” or “at least one first linear alkanediol” mean that the composition may contain one linear alkanediol having a carbon chain of 5 to 14 carbon atoms, or one first linear alkanediol having a carbon chain of 5 to 14 carbon atoms, or two or more linear alkanediols, or two or more linear alkanediols or two or more first linear alkanediols having carbon chains of 5 to 14 carbon atoms, i.e., two, three, four or more different linear alkanediols or first linear alkanediols having carbon chains of 5 to 14 carbon atoms.

[0126] The present invention provides for at least one linear alkanediol or at least one first linear alkanediol, which consists of a chain of 5 to 14 carbon atoms (preferably a carbon chain of 6 to 14 carbon atoms, more preferably a carbon chain of 7 to 14 carbon atoms, more preferably a carbon chain of 7 to 12 carbon atoms, even more preferably a carbon chain of 7 to 11 carbon atoms, even more preferably a carbon chain of 7 to 10 carbon atoms, most preferably a carbon chain of 7 to 9 carbon atoms, and most preferably a carbon chain of 7 or 8 carbon atoms).

[0127] The detergent and cleaning composition according to another aspect of the present invention contains at least one linear alkanediol or at least one first linear alkanediol having a carbon chain of 5 to 14 carbon atoms, selected from the group consisting of pentanediol, hexanediol, heptanediol, octanediol, nonanediol, decanediol, undecanediol, dodecanediol, tridecanediol, and tetradecanediol.

[0128] In a preferred variation, at least one linear alkanediol or at least one first linear alkanediol has a carbon chain of 5 to 13 carbon atoms and is selected from the group consisting of pentanediol, hexanediol, heptanediol, octanediol, nonanediol, decanediol, undecanediol, dodecanediol, and tridecanediol.

[0129] In a more preferred variation, at least one linear alkanediol or at least one first linear alkanediol has a carbon chain of 5 to 10 carbon atoms and is selected from the group consisting of pentanediol, hexanediol, heptanediol, octanediol, nonanediol, and decanediol.

[0130] In a more preferred variation, at least one linear alkanediol or at least one first linear alkanediol is selected from the group consisting of alkanediols having 5 to 8 fewer carbon atoms, i.e., pentanediol, hexanediol, heptanediol, octanediol, and any mixtures thereof; or selected from the group consisting of alkanediols having 6 to 8 carbon atoms, i.e., hexanediol, heptanediol, octanediol, and any mixtures thereof; or selected from the group consisting of alkanediols having 7 and 8 carbon atoms, i.e., heptanediol, octanediol, and any mixtures thereof.

[0131] In a preferred variation, at least one linear alkanediol or at least one first linear alkanediol has a carbon chain of 6 to 14 carbon atoms in the detergent and cleaning composition according to the present invention and is selected from the group consisting of hexanediol, heptanediol, octanediol, nonanediol, decanediol, undecanediol, dodecanediol, tridecanediol, and tetradecanediol.

[0132] In a preferred variation, at least one linear alkanediol or at least one first linear alkanediol has a carbon chain of 7 to 14 carbon atoms in the detergent and cleaning composition according to the present invention and is selected from the group consisting of heptanediol, octanediol, nonanediol, decanediol, undecanediol, dodecanediol, tridecanediol, and tetradecanediol.

[0133] In a more preferred variation, at least one linear alkanediol or at least one first linear alkanediol has a carbon chain of 7 to 12 carbon atoms in the detergent and cleaning composition according to the present invention and is selected from the group consisting of heptanediol, octanediol, nonanediol, decanediol, undecanediol, and dodecanediol.

[0134] In a more preferred variation, at least one linear alkanediol or at least one first linear alkanediol has a carbon chain of 7 to 10 carbon atoms in the detergent and cleaning composition according to the present invention and is selected from the group consisting of heptanediol, octanediol, nonanediol, and decanediol.

[0135] In the most preferred variation, at least one linear alkanediol or at least one first linear alkanediol has a carbon chain of 7 to 9 carbon atoms in the detergent and cleaning composition according to the present invention and is selected from the group consisting of heptanediol, octanediol, and nonanediol.

[0136] In the most preferred variation, at least one linear alkanediol or at least one first linear alkanediol has a carbon chain of 7 or 8 carbon atoms in the detergent and cleaning composition according to the present invention and is selected from the group consisting of heptanediol, octanediol, and nonanediol.

[0137] In a more preferred variation, at least one linear alkanediol or at least one first linear alkanediol is selected from the group consisting of alkanediols having 9 to 14 higher carbon atoms, i.e., nonanediols, decanediols, undecanediols, dodecanediols, tridecanediols, tetradecanediols and any mixtures thereof, or alkanediols having 9 to 13 carbon atoms, i.e., nonanediols, decanediols, undecanediols, dodecanediols, tridecanediols and any mixtures thereof. Selected from the group consisting of, or selected from the group consisting of alkanediols having 9 to 12 carbon atoms, i.e., nonanediols, decanediols, undecanediols, dodecanediols and any mixtures thereof, or selected from the group consisting of alkanediols having 9 to 11 carbon atoms, i.e., nonanediols, decanediols, undecanediols and any mixtures thereof, or selected from the group consisting of alkanediols having 9 and 10 carbon atoms, i.e., nonanediols, decanediols and any mixtures thereof.

[0138] In a more preferred variation, at least one linear alkanediol or at least one first linear alkanediol is one of pentanediol, hexanediol, heptanediol, or octanediol, or any mixture thereof.

[0139] In a more preferred variation, at least one linear alkanediol or at least one first linear alkanediol is one of heptanediol, octanediol, nonanediol, decanediol, undecanediol, or dodecanediol, or any mixture thereof.

[0140] In a more preferred variation, at least one linear alkanediol or at least one first linear alkanediol is any nonanediol, decanediol, undecanediol, or dodecanediol, or any mixture thereof.

[0141] In the most preferred variation, at least one linear alkanediol or at least the first linear alkanediol is a heptanediol.

[0142] In a second alternative, detergents and cleaning compositions according to another aspect of the present invention include a mixture comprising, as an enzyme stabilizer, at least one first linear alkanediol having a carbon chain of 5 to 14 carbon atoms (preferably a carbon chain of 6 to 14 carbon atoms, more preferably a carbon chain of 7 to 14 carbon atoms, more preferably a carbon chain of 7 to 12 carbon atoms, even more preferably a carbon chain of 7 to 11 carbon atoms, even more preferably a carbon chain of 7 to 10 carbon atoms, most preferably a carbon chain of 7 to 9 carbon atoms, most preferably a carbon chain of 7 or 8 carbon atoms), and one or more second linear alkanediols having a carbon chain of 5 to 14 carbon atoms (preferably a carbon chain of 6 to 14 carbon atoms, more preferably a carbon chain of 7 to 14 carbon atoms, more preferably a carbon chain of 7 to 12 carbon atoms, even more preferably a carbon chain of 7 to 11 carbon atoms, even more preferably a carbon chain of 7 to 10 carbon atoms, most preferably a carbon chain of 7 to 9 carbon atoms, most preferably a carbon chain of 7 or 8 carbon atoms).

[0143] This means that the enzyme stabilizer is an alkanediol mixture comprising at least one first linear alkanediol having a carbon chain of 5 to 14 carbon atoms and one or more, i.e., two, three, four or more second linear alkanediols having a carbon chain of 5 to 14 carbon atoms. In this alternative, the first linear alkanediol may be any of the alkanediols described herein, in general for linear alkanediols, and particularly for the first alternative in other embodiments.

[0144] For example, a mixture may contain one first linear alkanediol and one, two, three, or more second linear alkanediols; or a mixture may contain two first linear alkanediols and one, two, three, or more second linear alkanediols, provided that in each mixture, the first linear alkanediol and the second linear alkanediol are different from one another.

[0145] The second linear alkanediol preferably consists of a chain of 5 to 14 carbon atoms linked to each other by single covalent bonds, each having two OH functional groups bonded to two different carbon atoms in the chain.

[0146] The detergent and cleaning composition according to another aspect of the present invention includes at least one second linear alkanediol having a carbon chain of 5 to 14 carbon atoms, which is selected from the group consisting of pentanediol, hexanediol, heptanediol, octanediol, nonanediol, decanediol, undecanediol, dodecanediol, tridecanediol, and tetradecanediol.

[0147] In a preferred variation, at least one second linear alkanediol has a carbon chain of 5 to 13 carbon atoms and is selected from the group consisting of pentanediol, hexanediol, heptanediol, octanediol, nonanediol, decanediol, undecanediol, dodecanediol, and tridecanediol.

[0148] In a more preferred variation, at least one second linear alkanediol has a carbon chain of 5 to 10 carbon atoms and is selected from the group consisting of pentanediol, hexanediol, heptanediol, octanediol, nonanediol, and decanediol.

[0149] In a preferred variation, at least one second linear alkanediol has a carbon chain of 6 to 14 carbon atoms in the detergent and cleaning compositions according to other embodiments of the present invention and is selected from the group consisting of hexanediol, heptanediol, octanediol, nonanediol, decanediol, undecanediol, dodecanediol, tridecanediol, and tetradecanediol.

[0150] In a preferred variation, at least one second linear alkanediol has a carbon chain of 7 to 14 carbon atoms in the detergent and cleaning compositions according to other embodiments of the present invention and is selected from the group consisting of heptanediol, octanediol, nonanediol, decanediol, undecanediol, dodecanediol, tridecanediol, and tetradecanediol.

[0151] In a more preferred variation, at least one second linear alkanediol has a carbon chain of 7 to 12 carbon atoms in the detergent and cleaning compositions according to other embodiments of the present invention and is selected from the group consisting of heptanediol, octanediol, nonanediol, decanediol, undecanediol, and dodecanediol.

[0152] In a more preferred variation, at least one second linear alkanediol has a carbon chain of 7 to 11 carbon atoms in the detergent and cleaning compositions according to other embodiments of the present invention and is selected from the group consisting of heptanediol, octanediol, nonanediol, decanediol, and undecanediol.

[0153] In a more preferred variation, at least one second linear alkanediol has a carbon chain of 7 to 10 carbon atoms in the detergent and cleaning compositions according to other embodiments of the present invention and is selected from the group consisting of heptanediols, octanediols, nonanediols, and decanediols.

[0154] In the most preferred variation, at least one second linear alkanediol has a carbon chain of 7 to 9 carbon atoms in the detergent and cleaning compositions according to other embodiments of the present invention and is selected from the group consisting of heptanediols, octanediols, and nonanediols.

[0155] In the most preferred variation, at least one second linear alkanediol has a carbon chain of 7 or 8 carbon atoms in the detergent and cleaning compositions according to other embodiments of the present invention and is selected from the group consisting of heptanediols and octanediols.

[0156] In a more preferred variation, at least one second linear alkanediol is selected from the group consisting of pentanediol, hexanediol, heptanediol, octanediol, and nonanediol, most preferably hexanediol, heptanediol, octanediol, and nonanediol.

[0157] The phrase "different from each other" means that the first linear alkanediol and the second linear alkanediol in the mixture differ in terms of the length of their carbon chains, i.e., the number of carbon atoms, or in terms of their structural isomers.

[0158] Similarly, the number of carbon atoms in the first linear alkanediol and the second linear alkanediol in the mixture may be the same. For example, the first linear alkanediol and the second linear alkanediol may have a carbon chain of seven carbon atoms, but they may differ with respect to their structural isomers or their stereoisomers.

[0159] If both the first and second alkanediols are, for example, heptanediols, then according to the second option of the second embodiment, the second linear alkanediol, heptanediol, is a different structural isomer or stereoisomer from the first linear alkanediol.

[0160] In a preferred variation, the detergent and cleaning composition according to a second aspect of the present invention comprises a mixture of at least one first linear alkanediol having a carbon chain of 5 to 14 carbon atoms and one or more second linear alkanediols having a carbon chain of 5 to 14 carbon atoms, wherein the number of carbon atoms in the first and second alkanediols is the same or different.

[0161] When both the first and second alkanediols have the same number of carbon atoms, such a combination of alkanediols is also referred to herein as a “homoalkanediol mixture” or “homocombination.” For example, the first linear alkanediol and the second linear alkanediol have carbon chains of seven carbon atoms, but they differ with respect to their structural isomers or their stereoisomers.

[0162] When the first and second alkanediols have different numbers of carbon atoms, such a combination of alkanediols is also referred to herein as a “heteroalkanediol mixture” or “heterocombination.” For example, the first linear alkanediol has a carbon chain of seven carbon atoms, and the second linear alkanediol has a carbon chain of eight carbon atoms. However, beyond this, the first linear alkanediol and the second linear alkanediol may differ with respect to their structural isomers or their stereoisomers.

[0163] In a preferred variation, the present invention relates to detergents and cleaning compositions in which at least one linear alkanediol or a first linear alkanediol is selected from the group consisting of pentanediol, hexanediol, heptanediol, octanediol, nonanediol, decanediol, undecanediol, dodecanediol, tridecanediol and tetradecanediol, and / or a second linear alkanediol is selected from the group consisting of pentanediol, hexanediol, heptanediol, octanediol, nonanediol, decanediol, undecanediol, dodecanediol, tridecanediol and tetradecanediol.

[0164] Particularly preferred is an enzyme stabilizer mixture in which at least a first linear alkanediol is selected from alkanediols having a lower number of carbon atoms (5 to 8), and one or more second alkanediols are selected from alkanediols having a higher number of carbon atoms (9 to 14).

[0165] Most preferably, the enzyme stabilizer mixture comprises at least a first linear alkanediol selected from the group consisting of pentanediol, hexanediol, heptanediol, octanediol, and any mixtures thereof, and one or more second alkanediols selected from the group consisting of nonanediol, decanediol, undecanediol, dodecanediol, tridecanediol, and any mixtures thereof.

[0166] In the context of this invention, the term "alkanediol" also includes its structural isomers or positional isomers. Structural isomers are compounds having the same molecular formula and different bonding identities. Positional isomers, a specific form of structural isomerism, are structural isomers that can be considered to differ only in the position of a functional group on the parent structure, in this case in particular, in the position of two alcohol functional groups.

[0167] Depending on the number of carbon atoms in the carbon chain of the alkanediol, various positional isomers of the alkanediol exist: (x,x+1) structural isomer; (x,x+2) structural isomer; (x,x+3) structural isomer, etc.; and alpha and omega structural isomers when the alcohol functional group is at the end of the carbon chain, where x represents the number of carbon atoms in the alkanediol chain to which the OH group of the alkanediol is chemically bonded. For example, if x is 1, the two OH groups of the alkanediol are chemically bonded to carbon atoms C1 and C2 in the alkanediol chain; if x is 2, the two OH groups of the alkanediol are chemically bonded to carbon atoms C2 and C3 in the alkanediol chain, and so on.

[0168] In the (x,x+1) structural isomer, the two OH functional groups are vicinal, bonded to two different adjacent carbon atoms in the chain. In the (x,x+2) structural isomer, the two OH functional groups are bonded to two different carbon atoms in the chain, separated by one carbon atom. In the (x,x+3) structural isomer, the two OH functional groups are bonded to two different carbon atoms in the chain, separated by two carbon atoms. In the alpha and omega structural isomers, the two functional groups are bonded to the first carbon atom and the terminal carbon atom.

[0169] In preferred variations of the detergents and cleaning compositions according to the present invention, the linear alkanediol having a carbon chain of 5 to 14 carbon atoms is preferably a vicinal (x,x+1)diol selected from the group consisting of 1,2-diols, 2,3-diols, 3,4-diols, 4,5-diols, further (x,x+1)diols, and mixtures thereof, preferably an alpha,beta-1,2-structural isomer.

[0170] In a more preferred variation of the detergent and cleaning composition according to the present invention, the first linear alkanediol and / or second linear alkanediol having a carbon chain of 5 to 14 carbon atoms is a vicinal (x,x+1)diol selected from the group consisting of 1,2-diols, 2,3-diols, 3,4-diols, 4,5-diols, further (x,x+1)diols, and mixtures thereof, preferably an alpha, beta-1,2-structural isomer.

[0171] Preferably, the first linear alkanediol and / or the second linear alkanediol having a carbon chain of 5 to 14 carbon atoms is selected from 1,2-diols and / or 2,3-diols.

[0172] Therefore, according to a preferred modification of the detergent and cleaning composition according to the present invention, at least one linear alkanediol, a first linear alkanediol and / or a second linear alkanediol is an (x,x+1) structural isomer, where x represents the number of carbon atoms in the alkanediol chain to which the OH group of the alkanediol is chemically bonded, and is in particular a 1,2-alkanediol, a 2,3-alkanediol, a 3,4-alkanediol, or a mixture thereof, preferably a 1,2-alkanediol or a 2,3-alkanediol.

[0173] In a more preferred variation of the detergent and cleaning composition according to the present invention, the linear alkanediol having a carbon chain of 5 to 14 carbon atoms is preferably a non-vicinal (x,x+2)diol selected from the group consisting of 1,3-diols, 2,4-diols, 3,5-diols, further (x,x+2)diols, and mixtures thereof, preferably an alpha, gamma-1,3-structural isomer.

[0174] According to the present invention, vicinal (x,x+1) diols such as alpha, beta, or beta, gamma, or gamma, delta are most preferred.

[0175] In a more preferred variation of the detergent and cleaning composition according to the present invention, the linear alkanediol, particularly the first linear alkanediol and / or the second linear alkanediol, is a 1,2-alkanediol, a 2,3-alkanediol, a 3,4-alkanediol, or a mixture thereof, more preferably a 2,3-alkanediol.

[0176] 1,2-alkanediols of linear alkanediols, particularly a first linear alkanediol having a carbon chain of 5 to 14 carbon atoms and / or a second linear alkanediol having a carbon chain of 5 to 14 carbon atoms, may preferably be represented by the following formula:

[0177] [ka]

[0178] The linear alkanediols of the present invention, particularly the 2,3-alkanediols, and especially the first linear alkanediol having a carbon chain of 5 to 14 carbon atoms and / or the second linear alkanediol having a carbon chain of 5 to 14 carbon atoms, may preferably be represented by the following formula:

[0179] [ka]

[0180] A linear alkanediol, specifically a 3,4-alkanediol, preferably a first linear alkanediol having a carbon chain of 5 to 14 carbon atoms and / or a second linear alkanediol having a carbon chain of 5 to 14 carbon atoms, may preferably be represented by the following formula:

[0181] [ka]

[0182] In preferred variations of the detergent and cleaning composition according to the present invention, the linear alkanediol or the first linear alkanediol is 1,2-pentanediol, 2,3-pentanediol, 3,4-pentanediol, 1,2-Hexanediol, 2,3-Hexanediol, 3,4-Hexanediol, 1,2-heptanediol, 2,3-heptanediol, 3,4-heptanediol, 1,2-octanediol, 2,3-octanediol, 3,4-octanediol, 1,2-nonanediol, 2,3-nonanediol, 3,4-nonanediol, 1,2-decanediol, 2,3-decanediol, 3,4-decanediol, 1,2-Undecanediol, 2,3-Undecanediol, 3,4-Undecanediol 1,2-dodecanediol, 2,3-dodecanediol, 3,4-dodecanediol, 1,2-Tridecanediol, 2,3-Tridecanediol, 3,4-Tridecanediol, 1,2-tetradecanediol, 2,3-tetradecanediol, 3,4-tetradecanediol, Selected from the group consisting of and any mixture thereof.

[0183] In a more preferred variation of the detergent and cleaning composition according to the present invention, the linear alkanediol or the first linear alkanediol is 1,2-Hexanediol, 2,3-Hexanediol, 3,4-Hexanediol, 1,2-heptanediol, 2,3-heptanediol, 3,4-heptanediol, 1,2-octanediol, 2,3-octanediol, 3,4-octanediol, 1,2-nonanediol, 2,3-nonanediol, 3,4-nonanediol, 1,2-decanediol, 2,3-decanediol, 3,4-decanediol, 1,2-Undecanediol, 2,3-undecanediol, 3,4-undecanediol 1,2-Dodecanediol, 2,3-dodecanediol, 3,4-dodecanediol, 1,2-Tridecanediol, 2,3-tridecanediol, 3,4-tridecanediol, 1,2-Tetradecanediol, 2,3-tetradecanediol, 3,4-tetradecanediol, and is selected from the group consisting of any mixtures thereof.

[0184] In a further preferred variant of the detergent and cleaning composition according to the invention, the linear alkanediol or the first linear alkanediol is 1,2-Heptanediol, 2,3-heptanediol, 3,4-heptanediol, 1,2-Octanediol, 2,3-octanediol, 3,4-octanediol, 1,2-Nonanediol, 2,3-nonanediol, 3,4-nonanediol, 1,2-Decanediol, 2,3-decanediol, 3,4-decanediol, 1,2-Undecanediol, 2,3-undecanediol, 3,4-undecanediol 1,2-Dodecanediol, 2,3-dodecanediol, 3,4-dodecanediol, 1,2-Tridecanediol, 2,3-tridecanediol, 3,4-tridecanediol, 1,2-Tetradecanediol, 2,3-tetradecanediol, 3,4-tetradecanediol, and is selected from the group consisting of any mixtures thereof.

[0185] Even more preferably, the linear alkanediol or the first linear alkanediol is 1,2-Heptanediol, 2,3-heptanediol, 3,4-heptanediol, 1,2-Octanediol, 2,3-octanediol, 3,4-octanediol, 1,2-nonanediol, 2,3-nonanediol, 3,4-nonanediol, 1,2-decanediol, 2,3-decanediol, 3,4-decanediol, 1,2-Undecanediol, 2,3-Undecanediol, 3,4-Undecanediol 1,2-dodecanediol, 2,3-dodecanediol, 3,4-dodecanediol, Selected from the group consisting of and any mixture thereof.

[0186] More preferably, the linear alkanediol or the first linear alkanediol is 1,2-heptanediol, 2,3-heptanediol, 3,4-heptanediol, 1,2-octanediol, 2,3-octanediol, 3,4-octanediol, 1,2-nonanediol, 2,3-nonanediol, 3,4-nonanediol, 1,2-decanediol, 2,3-decanediol, 3,4-decanediol, 1,2-Undecanediol, 2,3-Undecanediol, 3,4-Undecanediol Selected from the group consisting of and any mixture thereof.

[0187] More preferably, the linear alkanediol or the first linear alkanediol is 1,2-heptanediol, 2,3-heptanediol, 3,4-heptanediol, 1,2-octanediol, 2,3-octanediol, 3,4-octanediol, 1,2-nonanediol, 2,3-nonanediol, 3,4-nonanediol, 1,2-decanediol, 2,3-decanediol, 3,4-decanediol, Selected from the group consisting of and any mixture thereof.

[0188] Most preferably, the linear alkanediol or the first linear alkanediol is 1,2-heptanediol, 2,3-heptanediol, 3,4-heptanediol, 1,2-octanediol, 2,3-octanediol, 3,4-octanediol, 1,2-nonanediol, 2,3-nonanediol, 3,4-nonanediol, Selected from the group consisting of and any mixture thereof.

[0189] Most preferably, the linear alkanediol or the first linear alkanediol is 1,2-heptanediol, 2,3-heptanediol, 3,4-heptanediol, 1,2-octanediol, 2,3-octanediol, 3,4-octanediol, Selected from the group consisting of and any mixture thereof.

[0190] According to a preferred modification, in the detergent and cleaning composition of the present invention, the linear alkanediol or the first linear alkanediol is selected from the group consisting of 1,2-pentanediol, 2,3-pentanediol, 1,2-hexanediol, 2,3-hexanediol, 1,2-heptanediol, 2,3-heptanediol, 1,2-octanediol, 2,3-octanediol, 1,2-nonanediol, 2,3-nonanediol, 1,2-decanediol, 2,3-decanediol, 1,2-undecanediol, 2,3-undecanediol, 1,2-dodecanediol, 2,3-dodecanediol, 1,2-tridecanediol, 2,3-tridecanediol, 1,2-tetradecanediol, 2,3-tetradecanediol, and any mixture thereof.

[0191] In a more preferred modification, in the detergent and cleaning composition according to the present invention, the linear alkanediol or the first linear alkanediol is selected from the group consisting of 1,2-hexanediol, 2,3-hexanediol, 1,2-heptanediol, 2,3-heptanediol, 1,2-octanediol, 2,3-octanediol, 1,2-nonanediol, 2,3-nonanediol, 1,2-decanediol, 2,3-decanediol, 1,2-undecanediol, 2,3-undecanediol, 1,2-dodecanediol, 2,3-dodecanediol, 1,2-tridecanediol, 2,3-tridecanediol, 1,2-tetradecanediol, 2,3-tetradecanediol, and any mixture thereof.

[0192] In a more preferred modification, in the detergent and cleaning composition according to the present invention, the linear alkanediol or the first linear alkanediol is selected from the group consisting of 1,2-heptanediol, 2,3-heptanediol, 1,2-octanediol, 2,3-octanediol, 1,2-nonanediol, 2,3-nonanediol, 1,2-decanediol, 2,3-decanediol, 1,2-undecanediol, 2,3-undecanediol, 1,2-dodecanediol, 2,3-dodecanediol, 1,2-tridecanediol, 2,3-tridecanediol, 1,2-tetradecanediol, 2,3-tetradecanediol, and any mixture thereof.

[0193] In a more preferred modification, in the detergent and cleaning composition according to the present invention, the linear alkanediol or the first linear alkanediol is selected from the group consisting of 1,2-heptanediol, 2,3-heptanediol, 1,2-octanediol, 2,3-octanediol, 1,2-nonanediol, 2,3-nonanediol, 1,2-decanediol, 2,3-decanediol, 1,2-undecanediol, 2,3-undecanediol, 1,2-dodecanediol, 2,3-dodecanediol, and any mixture thereof.

[0194] In a more preferred modification, in the detergent and cleaning composition according to the present invention, the linear alkanediol or the first linear alkanediol is selected from the group consisting of 1,2-heptanediol, 2,3-heptanediol, 1,2-octanediol, 2,3-octanediol, 1,2-nonanediol, 2,3-nonanediol, 1,2-decanediol, 2,3-decanediol, 1,2-undecanediol, 2,3-undecanediol, and any mixture thereof.

[0195] In a more preferred modification, in the detergent and cleaning composition according to the present invention, the linear alkanediol or the first linear alkanediol is selected from the group consisting of 1,2-heptanediol, 2,3-heptanediol, 1,2-octanediol, 2,3-octanediol, 1,2-nonanediol, 2,3-nonanediol, 1,2-decanediol, 2,3-decanediol, and any mixture thereof.

[0196] In the most preferred modification, in the detergent and cleaning composition according to the present invention, the linear alkanediol or the first linear alkanediol is selected from the group consisting of 1,2-heptanediol, 2,3-heptanediol, 1,2-octanediol, 2,3-octanediol, 1,2-nonanediol, 2,3-nonanediol, and any mixture thereof.

[0197] In the most preferred modification, in the detergent and cleaning composition according to the present invention, the linear alkanediol or the first linear alkanediol is selected from the group consisting of 1,2-heptanediol, 2,3-heptanediol, 1,2-octanediol, 2,3-octanediol, and any mixture thereof.

[0198] Among the aforementioned linear alkanediols or the first linear alkanediol, the following (x,x+1) structural isomers are preferred: 1,2-pentanediol, 2,3-pentanediol, 1,2-hexanediol, 2,3-hexanediol, 1,2-heptanediol, 2,3-heptanediol, 2,3-octanediol, 2,3-nonanediol, 2,3-decanediol, 2,3-undecanediol, 2,3-dodecanediol, 2,3-tridecanediol or a mixture thereof. The aforementioned alkanediol is a liquid with a purity of 90 to 99%.

[0199] Among the aforementioned liquid alkanediols, 1,2-pentanediol, 2,3-pentanediol, 1,2-hexanediol, 2,3-hexanediol, 1,2-heptanediol, 2,3-heptanediol, 2,3-octanediol, 2,3-nonanediol, or a mixture of the aforementioned liquid alkanediols is particularly preferred.

[0200] In a further preferred variant of the detergent and cleaning composition according to the invention, the linear alkanediol or the first linear alkanediol is 1,2-pentanediol, 2,3-pentanediol, 1,2-hexanediol, 2,3-hexanediol, 1,2-heptanediol, 2,3-heptanediol, 1,2-octanediol, 2,3-octanediol, and is selected from the group consisting of any mixture thereof.

[0201] In a further preferred variant of the detergent and cleaning composition according to the invention, the linear alkanediol or the first linear alkanediol is 1,2-hexanediol, 2,3-hexanediol, 1,2-heptanediol, 2,3-heptanediol, 1,2-octanediol, 2,3-octanediol, 1,2-nonanediol, 2,3-nonanediol 1,2-decanediol, 2,3-decanediol, 1,2-Undecanediol, 2,3-Undecanediol, 1,2-Dodecanediol, 2,3-Dodecanediol 1,2-Tridecanediol, 2,3-Tridecanediol, 1,2-tetradecanediol, 2,3-tetradecanediol, Selected from the group consisting of and any mixture thereof.

[0202] More preferably, in detergents and cleaning compositions according to a second aspect of the present invention, the linear alkanediol or the first linear alkanediol is selected from the group consisting of 1,2-pentanediol, 2,3-pentanediol, and mixtures thereof, or from the group consisting of 1,2-heptanediol, 2,3-heptanediol, and mixtures thereof. However, the linear alkanediol or the first linear alkanediol may also preferably be selected from the group consisting of 1,2-octanediol, 2,3-octanediol, and mixtures thereof.

[0203] More preferably, in the detergents and cleaning compositions according to the present invention, the linear alkanediol or the first linear alkanediol is an alpha, beta, or beta-gammadiol as one of 1,2-heptanediol or 2,3-heptanediol or a mixture thereof. However, the linear alkanediol or the first linear alkanediol may preferably be an alpha, beta, or beta-gammadiol as one of 1,2-octanediol or 2,3-octanediol or a mixture thereof. A mixture containing 1,2-heptanediol and 2,3-octanediol, or a mixture containing 1,2-octanediol and 2,3-heptanediol, is also possible.

[0204] Most preferably, the linear alkanediol or the first linear alkanediol is 1,2-pentanediol or 2,3-pentanediol or 1,2-hexanediol or 2,3-hexanediol or 1,2-heptanediol or 2,3-heptanediol or 1,2-octanediol or 2,3-octanediol or 1,2-nonanediol or 2,3-nonanediol.

[0205] Similarly, in a more preferred variation of the detergent and cleaning composition according to the present invention, the linear alkanediol or the first linear alkanediol is selected from the group consisting of 1,2-nonanediol, 2,3-nonanediol, 1,2-decanediol, 2,3-decanediol, 1,2-undecanediol, 2,3-undecanediol, 1,2-dodecanediol, 2,3-dodecanediol, and any mixture thereof.

[0206] More preferably, in the detergent and cleaning composition according to the present invention, the linear alkanediol or the first linear alkanediol is selected from the group consisting of 1,2-nonanediol, 2,3-nonanediol, and mixtures thereof, or preferably from the group consisting of 1,2-decanediol, 2,3-decanediol, and mixtures thereof, or preferably from the group consisting of 1,2-undecanediol, 2,3-undecanediol, and mixtures thereof.

[0207] In a more preferred variation, at least one linear alkanediol or at least one first linear alkanediol is selected from the group consisting of 1,2-alkanediols having 6 to 14 carbon atoms, namely 1,2-hexanediol, 1,2-heptanediol, 1,2-octanediol, 1,2-nonanediol, 1,2-decanediol, 1,2-undecanediol, 1,2-dodecanediol, 1,2-tridecanediol, 1,2-tetradecanediol, and any mixture thereof, or 7 to 14 1,2-alkanediols having 1,2 carbon atoms, namely 1,2-heptanediol, 1,2-octanediol, 1,2-nonanediol, 1,2-decanediol, 1,2-undecanediol, 1,2-dodecanediol, 1,2-tridecanediol, 1,2-tetradecanediol, and any mixture thereof, selected from the group, or 1,2-alkanediols having 7 to 12 carbon atoms, namely 1,2-heptanediol, 1,2-octanediol, 1,2-nonanediol, 1,2-decanediol A selection from the group consisting of ndiol, 1,2-undecanediol, 1,2-dodecanediol, and any mixture thereof, or a selection from the group consisting of 1,2-alkanediols having 7 to 11 carbon atoms, namely 1,2-heptanediol, 1,2-octanediol, 1,2-nonanediol, 1,2-decanediol, 1,2-undecanediol, and any mixture thereof, or a selection from the group consisting of 1,2-alkanediols having 7 to 10 carbon atoms, namely 1,2-heptanediol, 1,2-octanedi. The following are selected from the group consisting of anediols, 1,2-nonanediols, 1,2-decanediols, and any mixtures thereof; or selected from the group consisting of 1,2-alkanediols having 7 to 9 carbon atoms, namely 1,2-heptanediol, 1,2-octanediol, 1,2-nonanediols, and any mixtures thereof; or selected from the group consisting of 1,2-alkanediols having 7 and 8 carbon atoms, namely 1,2-heptanediol, 1,2-octanediol, and any mixtures thereof.

[0208] These 1,2-alkanediols were found to exhibit particularly remarkable enzyme-stabilizing properties. Therefore, the aforementioned alkanediols are efficient for use as enzyme stabilizers in detergents and cleaning compositions containing enzymes. Improved enzyme stability in detergents and cleaning compositions results in better cleaning performance, even when the compositions are stored.

[0209] In a more preferred variation, at least one linear alkanediol or at least one first linear alkanediol is selected from the group consisting of 1,2-alkanediols having 5 to 8 fewer carbon atoms, i.e., 1,2-pentanediol, 1,2-hexanediol, 1,2-heptanediol, 1,2-octanediol, and any mixtures thereof; or selected from the group consisting of 1,2-alkanediols having 6 to 8 carbon atoms, i.e., 1,2-hexanediol, 1,2-heptanediol, 1,2-octanediol, and any mixtures thereof; or selected from the group consisting of 1,2-alkanediols having 7 and 8 carbon atoms, i.e., 1,2-heptanediol, 1,2-octanediol, and any mixtures thereof.

[0210] In a more preferred variation, at least one linear alkanediol or at least one first linear alkanediol is any of 1,2-pentanediol, 1,2-hexanediol, 1,2-heptanediol, or 1,2-octanediol, or any mixture thereof.

[0211] In the most preferred variation, at least one linear alkanediol or at least the first linear alkanediol is 1,2-heptanediol.

[0212] These alkanediols were found to exhibit particularly remarkable enzyme-stabilizing properties. Therefore, 1,2-alkanediols with fewer carbon atoms are more efficient for use as enzyme stabilizers in detergents and cleaning compositions containing enzymes. Improved enzyme stability in detergents and cleaning compositions leads to better cleaning performance.

[0213] In a more preferred variation, at least one linear alkanediol or at least one first linear alkanediol is selected from the group consisting of 1,2-alkanediols having 9 to 14 higher carbon atoms, i.e., 1,2-nonanediol, 1,2-decanediol, 1,2-undecanediol, 1,2-dodecanediol, 1,2-tridecanediol, 1,2-tetradecanediol and any mixture thereof, or 1,2-alkanediols having 9 to 13 carbon atoms, i.e., 1,2-nonanediol, 1,2-decanediol, 1,2-undecanediol, 1,2-dodecanediol, 1,2-tridecanediol and any mixture thereof. Selected from the group consisting of substances, or selected from the group consisting of 1,2-alkanediols having 9 to 12 carbon atoms, i.e., 1,2-nonanediol, 1,2-decanediol, 1,2-undecanediol, 1,2-dodecanediol and any mixture thereof, or selected from the group consisting of 1,2-alkanediols having 9 to 11 carbon atoms, i.e., 1,2-nonanediol, 1,2-decanediol, 1,2-undecanediol and any mixture thereof, or selected from the group consisting of 1,2-alkanediols having 9 and 10 carbon atoms, i.e., 1,2-nonanediol, 1,2-decanediol and any mixture thereof.

[0214] In a more preferred variation, at least one linear alkanediol or at least one first linear alkanediol is any of 1,2-nonanediol, 1,2-decanediol, 1,2-undecanediol, or 1,2-dodecanediol, or any mixture thereof.

[0215] According to a preferred modification, at least one linear alkanediol or at least one first linear alkanediol is selected from the group consisting of 1,2-alkanediols having a higher number of carbon atoms, more specifically more than 10 carbon atoms, namely 1,2-undecanediol, 1,2-dodecanediol, 1,2-tridecanediol, or 1,2-tetradecanediol.

[0216] These alkanediols were found to exhibit remarkable enzyme stabilization properties. Therefore, 1,2-alkanediols with a higher number of carbon atoms, more specifically those with more than 10 carbon atoms, are efficient for use as enzyme stabilizers in detergents and cleaning compositions containing enzymes. Improved enzyme stability in detergents and cleaning compositions leads to better cleaning performance.

[0217] In a more preferred variation, at least one linear alkanediol or at least one first linear alkanediol is selected from the group consisting of 2,3-alkanediols having 6 to 14 carbon atoms, namely 2,3-hexanediol, 2,3-heptanediol, 2,3-octanediol, 2,3-nonanediol, 2,3-decanediol, 2,3-undecanediol, 2,3-dodecanediol, 2,3-tridecanediol, 2,3-tetradecanediol, and any mixture thereof, or 7 to 14 2,3-alkanediols having 1 carbon atom, namely 2,3-heptanediol, 2,3-octanediol, 2,3-nonanediol, 2,3-decanediol, 2,3-undecanediol, 2,3-dodecanediol, 2,3-tridecanediol, 2,3-tetradecanediol, and any mixture thereof, selected from the group, or 2,3-alkanediols having 7 to 12 carbon atoms, namely 2,3-heptanediol, 2,3-octanediol, 2,3-nonanediol, 2,3-decanediol A selection from the group consisting of diols, 2,3-undecanediol, 2,3-dodecanediol, and any mixture thereof, or a selection from the group consisting of 2,3-alkanediols having 7 to 11 carbon atoms, namely 2,3-heptanediol, 2,3-octanediol, 2,3-nonanediol, 2,3-decanediol, 2,3-undecanediol, and any mixture thereof, or a selection from the group consisting of 2,3-alkanediols having 7 to 10 carbon atoms, namely 2,3-heptanediol, 2,3-octanediol Selected from the group consisting of diols, 2,3-nonanediols, 2,3-decanediols, and any mixtures thereof; or selected from the group consisting of 2,3-alkanediols having 7 to 9 carbon atoms, namely 2,3-heptanediol, 2,3-octanediol, 2,3-nonanediols, and any mixtures thereof; or selected from the group consisting of 2,3-alkanediols having 7 and 8 carbon atoms, namely 2,3-heptanediol, 2,3-octanediol, and any mixtures thereof.

[0218] The aforementioned 2,3-alkanediols were found to exhibit particularly remarkable enzyme stabilization properties. Therefore, these alkanediols are efficient for use as enzyme stabilizers in detergents and cleaning compositions containing enzymes. Subsequently, the improved enzyme stability in the detergents and cleaning compositions results in better cleaning performance after storage compared to detergents and cleaning compositions without such alkanediols.

[0219] In a more preferred variation, the linear alkanediol or the first linear alkanediol is selected from the group consisting of 2,3-alkanediols having 5 to 8 fewer carbon atoms, i.e., 2,3-pentanediol, 2,3-hexanediol, 2,3-heptanediol, 2,3-octanediol, and any mixtures thereof; or selected from the group consisting of 2,3-alkanediols having 6 to 8 carbon atoms, i.e., 2,3-hexanediol, 2,3-heptanediol, 2,3-octanediol, and any mixtures thereof; or selected from the group consisting of 2,3-alkanediols having 7 and 8 carbon atoms, i.e., 1,2-heptanediol, 1,2-octanediol, and any mixtures thereof.

[0220] In a more preferred variation, at least one linear alkanediol or at least one first linear alkanediol is any of 2,3-pentanediol, 2,3-hexanediol, 2,3-heptanediol, or 2,3-octanediol, or any mixture thereof.

[0221] In the most preferred variation, at least one linear alkanediol or at least the first linear alkanediol is 2,3-heptanediol.

[0222] These alkanediols were found to exhibit particularly remarkable enzyme-stabilizing properties. Therefore, 2,3-alkanediols with fewer carbon atoms are more efficient for use as enzyme stabilizers in detergents and cleaning compositions containing enzymes. Improved enzyme stability in detergents and cleaning compositions results in better cleaning performance.

[0223] In a more preferred variation, at least one linear alkanediol or at least one first linear alkanediol is selected from the group consisting of 2,3-alkanediols having 9 to 14 higher carbon atoms, i.e., 2,3-nonanediol, 2,3-decanediol, 2,3-undecanediol, 2,3-dodecanediol, 2,3-tridecanediol, 2,3-tetradecanediol and any mixture thereof, or 2,3-alkanediols having 9 to 13 carbon atoms, i.e., 2,3-nonanediol, 2,3-decanediol, 2,3-undecanediol, 2,3-dodecanediol, 2,3-tetradecanediol and any mixture thereof Selected from the group consisting of compounds, or selected from the group consisting of 2,3-alkanediols having 9 to 12 carbon atoms, i.e., 2,3-nonanediol, 2,3-decanediol, 2,3-undecanediol, 2,3-dodecanediol and any mixture thereof, or selected from the group consisting of 2,3-alkanediols having 9 to 11 carbon atoms, i.e., 2,3-nonanediol, 2,3-decanediol, 2,3-undecanediol and any mixture thereof, or selected from the group consisting of 2,3-alkanediols having 9 and 10 carbon atoms, i.e., 2,3-nonanediol, 2,3-decanediol and any mixture thereof.

[0224] In a more preferred variation, at least one linear alkanediol or at least one first linear alkanediol is any of 2,3-nonanediol, 2,3-decanediol, 2,3-undecanediol, or 2,3-dodecanediol, or any mixture thereof.

[0225] According to a preferred modification, at least one linear alkanediol or at least one first linear alkanediol is selected from the group consisting of 2,3-alkanediols having a higher number of carbon atoms, more specifically more than 10 carbon atoms, namely 2,3-undecanediol, 2,3-dodecanediol, 2,3-tridecanediol, or 2,3-tetradecanediol.

[0226] These alkanediols were found to exhibit better enzyme stabilization properties. Therefore, 2,3-alkanediols with a higher number of carbon atoms, more specifically more than 10 carbon atoms, are efficient for use as enzyme stabilizers in detergents and cleaning compositions containing enzymes. Improved enzyme stability in detergents and cleaning compositions results in better cleaning performance.

[0227] In a preferred variation of the detergent and cleaning composition according to the present invention, the second linear alkanediol is 1,2-pentanediol, 2,3-pentanediol, 3,4-pentanediol, 1,2-Hexanediol, 2,3-Hexanediol, 3,4-Hexanediol, 1,2-heptanediol, 2,3-heptanediol, 3,4-heptanediol, 1,2-octanediol, 2,3-octanediol, 3,4-octanediol, 1,2-nonanediol, 2,3-nonanediol, 3,4-nonanediol, 1,2-decanediol, 2,3-decanediol, 3,4-decanediol, 1,2-Undecanediol, 2,3-Undecanediol, 3,4-Undecanediol, 1,2-dodecanediol, 2,3-dodecanediol, 3,4-dodecanediol, 1,2-Tridecanediol, 2,3-Tridecanediol, 3,4-Tridecanediol, 1,2-tetradecanediol, 2,3-tetradecanediol, 3,4-tetradecanediol, Selected from the group consisting of and any mixture thereof.

[0228] In a more preferred variation of the detergent and cleaning composition according to the present invention, the second linear alkanediol is 1,2-Hexanediol, 2,3-Hexanediol, 3,4-Hexanediol, 1,2-heptanediol, 2,3-heptanediol, 3,4-heptanediol, 1,2-octanediol, 2,3-octanediol, 3,4-octanediol, 1,2-nonanediol, 2,3-nonanediol, 3,4-nonanediol, 1,2-decanediol, 2,3-decanediol, 3,4-decanediol, 1,2-Undecanediol, 2,3-Undecanediol, 3,4-Undecanediol, 1,2-dodecanediol, 2,3-dodecanediol, 3,4-dodecanediol, 1,2-Tridecanediol, 2,3-Tridecanediol, 3,4-Tridecanediol, 1,2-tetradecanediol, 2,3-tetradecanediol, 3,4-tetradecanediol, Selected from the group consisting of and any mixture thereof.

[0229] In a more preferred variation of the detergent and cleaning composition according to the present invention, the second linear alkanediol is 1,2-heptanediol, 2,3-heptanediol, 3,4-heptanediol, 1,2-octanediol, 2,3-octanediol, 3,4-octanediol, 1,2-nonanediol, 2,3-nonanediol, 3,4-nonanediol, 1,2-decanediol, 2,3-decanediol, 3,4-decanediol, 1,2-Undecanediol, 2,3-Undecanediol, 3,4-Undecanediol, 1,2-dodecanediol, 2,3-dodecanediol, 3,4-dodecanediol, 1,2-Tridecanediol, 2,3-Tridecanediol, 3,4-Tridecanediol, 1,2-tetradecanediol, 2,3-tetradecanediol, 3,4-tetradecanediol, Selected from the group consisting of and any mixture thereof.

[0230] More preferably, the second linear alkanediol is 1,2-heptanediol, 2,3-heptanediol, 3,4-heptanediol, 1,2-octanediol, 2,3-octanediol, 3,4-octanediol, 1,2-nonanediol, 2,3-nonanediol, 3,4-nonanediol, 1,2-decanediol, 2,3-decanediol, 3,4-decanediol, 1,2-Undecanediol, 2,3-Undecanediol, 3,4-Undecanediol, 1,2-dodecanediol, 2,3-dodecanediol, 3,4-dodecanediol, Selected from the group consisting of and any mixture thereof.

[0231] More preferably, the second linear alkanediol is 1,2-heptanediol, 2,3-heptanediol, 3,4-heptanediol, 1,2-octanediol, 2,3-octanediol, 3,4-octanediol, 1,2-nonanediol, 2,3-nonanediol, 3,4-nonanediol, 1,2-decanediol, 2,3-decanediol, 3,4-decanediol, 1,2-Undecanediol, 2,3-Undecanediol, 3,4-Undecanediol, Selected from the group consisting of and any mixture thereof.

[0232] More preferably, the second linear alkanediol is 1,2-heptanediol, 2,3-heptanediol, 3,4-heptanediol, 1,2-octanediol, 2,3-octanediol, 3,4-octanediol, 1,2-nonanediol, 2,3-nonanediol, 3,4-nonanediol, 1,2-decanediol, 2,3-decanediol, 3,4-decanediol, Selected from the group consisting of and any mixture thereof.

[0233] Most preferably, the second linear alkanediol is 1,2-heptanediol, 2,3-heptanediol, 3,4-heptanediol, 1,2-octanediol, 2,3-octanediol, 3,4-octanediol, 1,2-nonanediol, 2,3-nonanediol, 3,4-nonanediol, Selected from the group consisting of and any mixture thereof.

[0234] Most preferably, the second linear alkanediol is 1,2-heptanediol, 2,3-heptanediol, 3,4-heptanediol, 1,2-octanediol, 2,3-octanediol, 3,4-octanediol, Selected from the group consisting of and any mixture thereof.

[0235] According to a preferred modification, in the detergent and cleaning composition of the present invention, the second linear alkanediol is selected from the group consisting of 1,2-pentanediol, 2,3-pentanediol, 1,2-hexanediol, 2,3-hexanediol, 1,2-heptanediol, 2,3-heptanediol, 1,2-octanediol, 2,3-octanediol, 1,2-nonanediol, 2,3-nonanediol, 1,2-decanediol, 2,3-decanediol, 1,2-undecanediol, 2,3-undecanediol, 1,2-dodecanediol, 2,3-dodecanediol, 1,2-tridecanediol, 2,3-tridecanediol, and any mixture thereof.

[0236] According to a preferred modification, in the detergent and cleaning composition of the present invention, the second linear alkanediol is selected from the group consisting of 1,2-hexanediol, 2,3-hexanediol, 1,2-heptanediol, 2,3-heptanediol, 1,2-octanediol, 2,3-octanediol, 1,2-nonanediol, 2,3-nonanediol, 1,2-decanediol, 2,3-decanediol, 1,2-undecanediol, 2,3-undecanediol, 1,2-dodecanediol, 2,3-dodecanediol, 1,2-tridecanediol, 2,3-tridecanediol, 1,2-tetradecanediol, 2,3-tetradecanediol, and any mixture thereof.

[0237] According to a preferred modification, in the detergent and cleaning composition of the present invention, the second linear alkanediol is selected from the group consisting of 1,2-heptanediol, 2,3-heptanediol, 1,2-octanediol, 2,3-octanediol, 1,2-nonanediol, 2,3-nonanediol, 1,2-decanediol, 2,3-decanediol, 1,2-undecanediol, 2,3-undecanediol, 1,2-dodecanediol, 2,3-dodecanediol, 1,2-tridecanediol, 2,3-tridecanediol, 1,2-tetradecanediol, 2,3-tetradecanediol, and any mixture thereof.

[0238] In a more preferred modification, in the detergent and cleaning composition according to the present invention, the second linear alkanediol is selected from the group consisting of 1,2-heptanediol, 2,3-heptanediol, 1,2-octanediol, 2,3-octanediol, 1,2-nonanediol, 2,3-nonanediol, 1,2-decanediol, 2,3-decanediol, 1,2-undecanediol, 2,3-undecanediol, 1,2-dodecanediol, 2,3-dodecanediol, and any mixture thereof.

[0239] In a more preferred modification, in the detergent and cleaning composition according to the present invention, the second linear alkanediol is selected from the group consisting of 1,2-heptanediol, 2,3-heptanediol, 1,2-octanediol, 2,3-octanediol, 1,2-nonanediol, 2,3-nonanediol, 1,2-decanediol, 2,3-decanediol, 1,2-undecanediol, 2,3-undecanediol, and any mixture thereof.

[0240] In a more preferred modification, in the detergent and cleaning composition according to the present invention, the second linear alkanediol is selected from the group consisting of 1,2-heptanediol, 2,3-heptanediol, 1,2-octanediol, 2,3-octanediol, 1,2-nonanediol, 2,3-nonanediol, 1,2-decanediol, 2,3-decanediol, and any mixture thereof.

[0241] In the most preferred modification, in the detergent and cleaning composition according to the present invention, the second linear alkanediol is selected from the group consisting of 1,2-heptanediol, 2,3-heptanediol, 1,2-octanediol, 2,3-octanediol, 1,2-nonanediol, 2,3-nonanediol, and any mixture thereof.

[0242] In the most preferred modification, in the detergent and cleaning composition according to the present invention, the second linear alkanediol is selected from the group consisting of 1,2-heptanediol, 2,3-heptanediol, 1,2-octanediol, 2,3-octanediol, and any mixture thereof.

[0243] Of the aforementioned second linear alkanediols, the following (x,x+1) structural isomers are preferred: 1,2-pentanediol, 2,3-pentanediol, 1,2-hexanediol, 2,3-hexanediol, 1,2-heptanediol, 2,3-heptanediol, 2,3-octanediol, 2,3-nonanediol, 2,3-decanediol, 2,3-undecanediol, 2,3-dodecanediol, or 2,3-tridecanediol. The aforementioned alkanediols are liquid with a purity of 90-99%.

[0244] Of the aforementioned liquid alkanediols, 1,2-pentanediol, 2,3-pentanediol, 1,2-hexanediol, 2,3-hexanediol, 1,2-heptanediol, 2,3-heptanediol, 2,3-octanediol, 2,3-nonanediol, or mixtures of the aforementioned liquid alkanediols are particularly preferred.

[0245] In a more preferred variation of the detergent and cleaning composition according to the present invention, the second linear alkanediol is 1,2-pentanediol, 2,3-pentanediol, 1,2-Hexanediol, 2,3-Hexanediol, 1,2-heptanediol, 2,3-heptanediol, 1,2-octanediol, 2,3-octanediol, 1,2-nonanediol, 2,3-nonanediol, 1,2-decanediol, 2,3-decanediol, 1,2-Undecanediol, 2,3-Undecanediol, 1,2-Dodecanediol, 2,3-Dodecanediol 1,2-Tridecanediol, 2,3-Tridecanediol, 1,2-tetradecanediol, 2,3-tetradecanediol, Selected from the group consisting of and any mixture thereof.

[0246] More preferably, in the detergents and cleaning compositions according to the present invention, the second linear alkanediol is selected from the group consisting of 1,2-pentanediol, 2,3-pentanediol, and mixtures thereof, or from the group consisting of 1,2-heptanediol, 2,3-heptanediol, and mixtures thereof. However, the second linear alkanediol may also preferably be selected from the group consisting of 1,2-octanediol, 2,3-octanediol, and mixtures thereof.

[0247] More preferably, in the detergents and cleaning compositions according to the present invention, the second linear alkanediol is an alpha, beta, or beta-gammadiol as either 1,2-pentanediol or 2,3-pentanediol or a mixture thereof. However, the second linear alkanediol may also preferably be an alpha, beta, or beta-gammadiol as either 1,2-hexanediol or 2,3-hexanediol or a mixture thereof. A mixture containing 1,2-pentanediol and 2,3-hexanediol, or a mixture containing 2,3-pentanediol and 1,2-hexanediol is also possible.

[0248] Most preferably, the second linear alkanediol is 1,2-pentanediol or 2,3-pentanediol or 1,2-hexanediol or 2,3-hexanediol or 1,2-heptanediol or 2,3-heptanediol or 2,3-octanediol or 2,3-nonanediol.

[0249] Similarly, in a more preferred variation of the detergent and cleaning composition according to the present invention, the second linear alkanediol is selected from the group consisting of 1,2-nonanediol, 2,3-nonanediol, 1,2-decanediol, 2,3-decanediol, 1,2-undecanediol, 2,3-undecanediol, 1,2-dodecanediol, 2,3-dodecanediol, and any mixture thereof.

[0250] More preferably, in the detergent and cleaning composition according to the present invention, the second linear alkanediol is selected from the group consisting of 1,2-nonanediol, 2,3-nonanediol, and mixtures thereof, or preferably from the group consisting of 1,2-decanediol, 2,3-decanediol, and mixtures thereof, or preferably from the group consisting of 1,2-undecanediol, 2,3-undecanediol, and mixtures thereof.

[0251] In a more preferred variation, at least one second linear alkanediol is selected from the group consisting of 1,2-alkanediols having 6 to 14 carbon atoms, namely 1,2-hexanediol, 1,2-heptanediol, 1,2-octanediol, 1,2-nonanediol, 1,2-decanediol, 1,2-undecanediol, 1,2-dodecanediol, 1,2-tridecanediol, 1,2-tetradecanediol, and any mixture thereof, or 1,2-alkanediols having 7 to 14 carbon atoms Alkanediols, namely 1,2-heptanediol, 1,2-octanediol, 1,2-nonanediol, 1,2-decanediol, 1,2-undecanediol, 1,2-dodecanediol, 1,2-tridecanediol, 1,2-tetradecanediol, and any mixture thereof, selected from the group, or 1,2-alkanediols having 7 to 12 carbon atoms, namely 1,2-heptanediol, 1,2-octanediol, 1,2-nonanediol, 1,2-decanediol, 1,2- Selected from the group consisting of undecanediol, 1,2-dodecanediol, and any mixture thereof, or selected from the group consisting of 1,2-alkanediols having 7 to 11 carbon atoms, namely 1,2-heptanediol, 1,2-octanediol, 1,2-nonanediol, 1,2-decanediol, 1,2-undecanediol, and any mixture thereof, or 1,2-alkanediols having 7 to 10 carbon atoms, namely 1,2-heptanediol, 1,2-octanediol Selected from the group consisting of 1,2-nonanediol, 1,2-decanediol, and any mixture thereof, or selected from the group consisting of 1,2-alkanediols having 7 to 9 carbon atoms, namely 1,2-heptanediol, 1,2-octanediol, 1,2-nonanediol, and any mixture thereof, or selected from the group consisting of 1,2-alkanediols having 7 and 8 carbon atoms, namely 1,2-heptanediol, 1,2-octanediol, and any mixture thereof.

[0252] These 1,2-alkanediols were found to exhibit particularly remarkable enzyme-stabilizing properties. Therefore, the aforementioned alkanediols are efficient for use as enzyme stabilizers in detergents and cleaning compositions containing enzymes. Improved enzyme stability in detergents and cleaning compositions results in better cleaning performance, even when the compositions are stored.

[0253] In a more preferred variation, the second linear alkanediol is selected from the group consisting of 1,2-alkanediols having fewer than 5 to 8 carbon atoms, i.e., 1,2-pentanediol, 1,2-hexanediol, 1,2-heptanediol, 1,2-octanediol, and any mixtures thereof; or selected from the group consisting of 1,2-alkanediols having 6 to 8 carbon atoms, i.e., 1,2-hexanediol, 1,2-heptanediol, 1,2-octanediol, and any mixtures thereof; or selected from the group consisting of 1,2-alkanediols having 7 and 8 carbon atoms, i.e., 1,2-heptanediol, 1,2-octanediol, and any mixtures thereof.

[0254] In a more preferred variation, the second linear alkanediol is any of 1,2-pentanediol, 1,2-hexanediol, 1,2-heptanediol, or 1,2-octanediol, or any mixture thereof. In a more preferred variation, the second linear alkanediol is any of 1,2-heptanediol, 1,2-octanediol, or any mixture thereof.

[0255] In the most preferred variation, the second linear alkanediol is 1,2-heptanediol.

[0256] These alkanediols were found to exhibit particularly remarkable enzyme-stabilizing properties. Therefore, 1,2-alkanediols with fewer carbon atoms are more efficient for use as enzyme stabilizers in detergents and cleaning compositions containing enzymes. Improved enzyme stability in detergents and cleaning compositions leads to better cleaning performance.

[0257] In a more preferred variation, the second linear alkanediol is selected from the group consisting of 1,2-alkanediols having a higher number of carbon atoms (9 to 14), namely 1,2-nonanediol, 1,2-decanediol, 1,2-undecanediol, 1,2-dodecanediol, 1,2-tridecanediol, 1,2-tetradecanediol and any mixture thereof, or from the group consisting of 1,2-alkanediols having a higher number of carbon atoms (9 to 13), namely 1,2-nonanediol, 1,2-decanediol, 1,2-undecanediol, 1,2-dodecanediol, 1,2-tridecanediol and any mixture thereof. or selected from the group consisting of 1,2-alkanediols having 9 to 12 carbon atoms, i.e., 1,2-nonanediol, 1,2-decanediol, 1,2-undecanediol, 1,2-dodecanediol and any mixture thereof, or selected from the group consisting of 1,2-alkanediols having 9 to 11 carbon atoms, i.e., 1,2-nonanediol, 1,2-decanediol, 1,2-undecanediol and any mixture thereof, or selected from the group consisting of 1,2-alkanediols having 9 and 10 carbon atoms, i.e., 1,2-nonanediol, 1,2-decanediol and any mixture thereof.

[0258] In a more preferred variation, the second linear alkanediol is one of 1,2-nonanediol, 1,2-decanediol, 1,2-undecanediol, or 1,2-dodecanediol, or any mixture thereof.

[0259] According to a preferred modification, the second linear alkanediol is selected from the group consisting of 1,2-alkanediols having a higher number of carbon atoms, more specifically more than 10 carbon atoms, namely 1,2-undecanediol, 1,2-dodecanediol, 1,2-tridecanediol, or 1,2-tetradecanediol.

[0260] These alkanediols were found to exhibit better enzyme stabilization properties. Therefore, 1,2-alkanediols with a higher number of carbon atoms, more specifically more than 10 carbon atoms, are efficient for use as enzyme stabilizers in detergents and cleaning compositions containing enzymes. Improved enzyme stability in detergents and cleaning compositions results in better cleaning performance.

[0261] In a more preferred variation, at least one second linear alkanediol is selected from the group consisting of 2,3-alkanediols having 6 to 14 carbon atoms, namely 2,3-hexanediol, 2,3-heptanediol, 2,3-octanediol, 2,3-nonanediol, 2,3-decanediol, 2,3-undecanediol, 2,3-dodecanediol, 2,3-tridecanediol, 2,3-tetradecanediol, and any mixture thereof, or 2,3-alkanediols having 7 to 14 carbon atoms Alkanediols, namely 2,3-heptanediol, 2,3-octanediol, 2,3-nonanediol, 2,3-decanediol, 2,3-undecanediol, 2,3-dodecanediol, 2,3-tridecanediol, 2,3-tetradecanediol, and any mixture thereof, selected from the group, or 2,3-alkanediols having 7 to 12 carbon atoms, namely 2,3-heptanediol, 2,3-octanediol, 2,3-nonanediol, 2,3-decanediol, 2,3- Selected from the group consisting of undecanediol, 2,3-dodecanediol, and any mixture thereof, or selected from the group consisting of 2,3-alkanediols having 7 to 11 carbon atoms, namely 2,3-heptanediol, 2,3-octanediol, 2,3-nonanediol, 2,3-decanediol, 2,3-undecanediol, and any mixture thereof, or 2,3-alkanediols having 7 to 10 carbon atoms, namely 2,3-heptanediol, 2,3-octanediol Selected from the group consisting of 2,3-nonanediol, 2,3-decanediol, and any mixture thereof, or selected from the group consisting of 2,3-alkanediols having 7 to 9 carbon atoms, namely 2,3-heptanediol, 2,3-octanediol, 2,3-nonanediol, and any mixture thereof, or selected from the group consisting of 2,3-alkanediols having 7 and 8 carbon atoms, namely 2,3-heptanediol, 2,3-octanediol, and any mixture thereof.

[0262] The aforementioned 2,3-alkanediols were found to exhibit particularly remarkable enzyme stabilization properties. Therefore, these alkanediols are efficient for use as enzyme stabilizers in detergents and cleaning compositions containing enzymes. Subsequently, the improved enzyme stability in the detergents and cleaning compositions results in better cleaning performance after storage compared to detergents and cleaning compositions without such alkanediols.

[0263] In a more preferred variation, the second linear alkanediol is selected from the group consisting of 2,3-alkanediols having fewer than 5 to 8 carbon atoms, namely 2,3-pentanediol, 2,3-hexanediol, 2,3-heptanediol, 2,3-octanediol, and any mixtures thereof; or selected from the group consisting of 2,3-alkanediols having 6 to 8 carbon atoms, namely 2,3-hexanediol, 2,3-heptanediol, 2,3-octanediol, and any mixtures thereof; or selected from the group consisting of 2,3-alkanediols having 7 and 8 carbon atoms, namely 1,2-heptanediol, 1,2-octanediol, and any mixtures thereof.

[0264] In a more preferred variation, the second linear alkanediol is any of 2,3-pentanediol, 2,3-hexanediol, 2,3-heptanediol, or 2,3-octanediol, or any mixture thereof. In a more preferred variation, the second linear alkanediol is any of 2,3-heptanediol, 2,3-octanediol, or any mixture thereof.

[0265] In the most preferred variation, the second linear alkanediol is 2,3-heptanediol.

[0266] These alkanediols were found to exhibit particularly remarkable enzyme-stabilizing properties. Therefore, 2,3-alkanediols with fewer carbon atoms are more efficient for use as enzyme stabilizers in detergents and cleaning compositions containing enzymes. Improved enzyme stability in detergents and cleaning compositions results in better cleaning performance.

[0267] In a more preferred variation, the second linear alkanediol is selected from the group consisting of 2,3-alkanediols having a higher number of carbon atoms (9 to 14), namely 2,3-nonanediol, 2,3-decanediol, 2,3-undecanediol, 2,3-dodecanediol, 2,3-tridecanediol, 2,3-tetradecanediol and any mixture thereof, or from the group consisting of 2,3-alkanediols having a higher number of carbon atoms (9 to 13), namely 2,3-nonanediol, 2,3-decanediol, 2,3-undecanediol, 2,3-dodecanediol, 2,3-tridecanediol and any mixture thereof. or selected from the group consisting of 2,3-alkanediols having 9 to 12 carbon atoms, i.e., 2,3-nonanediol, 2,3-decanediol, 2,3-undecanediol, 2,3-dodecanediol and any mixture thereof, or selected from the group consisting of 2,3-alkanediols having 9 to 11 carbon atoms, i.e., 2,3-nonanediol, 2,3-decanediol, 2,3-undecanediol and any mixture thereof, or selected from the group consisting of 2,3-alkanediols having 9 and 10 carbon atoms, i.e., 2,3-nonanediol, 2,3-decanediol and any mixture thereof.

[0268] In a more preferred variation, the second linear alkanediol is one of 2,3-nonanediol, 2,3-decanediol, 2,3-undecanediol, or 2,3-dodecanediol, or any mixture thereof.

[0269] According to a preferred modification, the second linear alkanediol is selected from the group consisting of 2,3-alkanediols having a higher number of carbon atoms, more specifically more than 10 carbon atoms, namely 2,3-undecanediol, 2,3-dodecanediol, 2,3-tridecanediol, or 2,3-tetradecanediol.

[0270] These alkanediols were found to exhibit better enzyme stabilization properties. Therefore, 2,3-alkanediols with a higher number of carbon atoms, more specifically more than 10 carbon atoms, are efficient for use as enzyme stabilizers in detergents and cleaning compositions containing enzymes. Improved enzyme stability in detergents and cleaning compositions results in better cleaning performance.

[0271] In a more preferred variation, in the detergent and cleaning composition according to the present invention, at least one linear alkanediol or a first linear alkanediol is selected from the group consisting of 1,2-pentanediol, 2,3-pentanediol, 1,2-hexanediol, 2,3-hexanediol, 1,2-heptanediol, 2,3-heptanediol, 1,2-octanediol, 2,3-octanediol, 1,2-nonanediol, 2,3-nonanediol, 1,2-decanediol, 2,3-decanediol, 1,2-undecanediol, 2,3-undecanediol, 1,2-dodecanediol, 2,3-dodecanediol, 1,2-tridecanediol, 2,3-tridecanediol, 1,2-tetradecanediol, 2,3-tetradecanediol, and any mixture thereof, and / or The second linear alkanediol is selected from the group consisting of 1,2-pentanediol, 2,3-pentanediol, 1,2-hexanediol, 2,3-hexanediol, 1,2-heptanediol, 2,3-heptanediol, 1,2-octanediol, 2,3-octanediol, 1,2-nonanediol, 2,3-nonanediol, 1,2-decanediol, 2,3-decanediol, 1,2-undecanediol, 2,3-undecanediol, 1,2-dodecanediol, 2,3-dodecanediol, 1,2-tridecanediol, 2,3-tridecanediol, 1,2-tetradecanediol, 2,3-tetradecanediol, and any mixture thereof.

[0272] Therefore, in a more preferred variation, the detergent and cleaning composition according to the present invention, comprising a mixture or combination containing at least one first linear alkanediol and one or more second linear alkanediols, comprises any one of the following mixtures / combinations: • A combination of 1,2-pentanediol and one of 1,2-hexanediol, 1,2-heptanediol, 1,2-octanediol, 1,2-nonanediol, 1,2-decanediol, 1,2-undecanediol, 1,2-dodecanediol, 1,2-tridecanediol, or 1,2-tetradecanediol; or • A combination of 1,2-hexanediol and one of 1,2-pentanediol, 1,2-heptanediol, 1,2-octanediol, 1,2-nonanediol, 1,2-decanediol, 1,2-undecanediol, 1,2-dodecanediol, 1,2-tridecanediol, or 1,2-tetradecanediol; or • A combination of 1,2-heptanediol and one of 1,2-pentanediol, 1,2-hexanediol, 1,2-octanediol, 1,2-nonanediol, 1,2-decanediol, 1,2-undecanediol, 1,2-dodecanediol, 1,2-tridecanediol, or 1,2-tetradecanediol; or • A combination of 1,2-octanediol and one of 1,2-pentanediol, 1,2-hexanediol, 1,2-heptanediol, 1,2-nonanediol, 1,2-decanediol, 1,2-undecanediol, 1,2-dodecanediol, 1,2-tridecanediol, or 1,2-tetradecanediol; or • A combination of 1,2-nonanediol and one of 1,2-pentanediol, 1,2-hexanediol, 1,2-heptanediol, 1,2-octanediol, 1,2-decanediol, 1,2-undecanediol, 1,2-dodecanediol, 1,2-tridecanediol, or 1,2-tetradecanediol; or • A combination of 1,2-decanediol and one of 1,2-pentanediol, 1,2-hexanediol, 1,2-heptanediol, 1,2-octanediol, 1,2-nonanediol, 1,2-undecanediol, 1,2-dodecanediol, 1,2-tridecanediol, or 1,2-tetradecanediol; or • A combination of 1,2-undecanediol and one of 1,2-pentanediol, 1,2-hexanediol, 1,2-heptanediol, 1,2-octanediol, 1,2-nonanediol, 1,2-decanediol, 1,2-dodecanediol, 1,2-tridecanediol or 1,2-tetradecanediol; or • A combination of 1,2-dodecanediol and one of 1,2-pentanediol, 1,2-hexanediol, 1,2-heptanediol, 1,2-octanediol, 1,2-nonanediol, 1,2-decanediol, 1,2-undecanediol, 1,2-tridecanediol, or 1,2-tetradecanediol; or • A combination of 1,2-tridecanediol and one of 1,2-pentanediol, 1,2-hexanediol, 1,2-heptanediol, 1,2-octanediol, 1,2-nonanediol, 1,2-decanediol, 1,2-undecanediol, 1,2-dodecanediol, or 1,2-tetradecanediol; or • A combination of 1,2-tetradecanediol and one of 1,2-pentanediol, 1,2-hexanediol, 1,2-heptanediol, 1,2-octanediol, 1,2-nonanediol, 1,2-decanediol, 1,2-undecanediol, 1,2-dodecanediol, or 1,2-tridecanediol; or • A combination of 1,2-pentanediol and one of the following: 2,3-pentanediol, 2,3-hexanediol, 2,3-heptanediol, 2,3-octanediol, 2,3-nonanediol, 2,3-decanediol, 2,3-undecanediol, 2,3-dodecanediol, 2,3-tridecanediol, or 2,3-tetradecanediol; or • A combination of 1,2-hexanediol and one of the following: 2,3-pentanediol, 2,3-hexanediol, 2,3-heptanediol, 2,3-octanediol, 2,3-nonanediol, 2,3-decanediol, 2,3-undecanediol, 2,3-dodecanediol, 2,3-tridecanediol, or 2,3-tetradecanediol; or • A combination of 1,2-heptanediol and one of the following: 2,3-pentanediol, 2,3-hexanediol, 2,3-heptanediol, 2,3-octanediol, 2,3-nonanediol, 2,3-decanediol, 2,3-undecanediol, 2,3-dodecanediol, 2,3-tridecanediol, or 2,3-tetradecanediol; or • A combination of 1,2-octanediol and one of the following: 2,3-pentanediol, 2,3-hexanediol, 2,3-heptanediol, 2,3-octanediol, 2,3-nonanediol, 2,3-decanediol, 2,3-undecanediol, 2,3-dodecanediol, 2,3-tridecanediol, or 2,3-tetradecanediol; or • A combination of 1,2-nonanediol and one of the following: 2,3-pentanediol, 2,3-hexanediol, 2,3-heptanediol, 2,3-octanediol, 2,3-nonanediol, 2,3-decanediol, 2,3-undecanediol, 2,3-dodecanediol, 2,3-tridecanediol, or 2,3-tetradecanediol; or • A combination of 1,2-decanediol and one of the following: 2,3-pentanediol, 2,3-hexanediol, 2,3-heptanediol, 2,3-octanediol, 2,3-nonanediol, 2,3-decanediol, 2,3-undecanediol, 2,3-dodecanediol, 2,3-tridecanediol, or 2,3-tetradecanediol; or • A combination of 1,2-undecanediol and one of the following: 2,3-pentanediol, 2,3-hexanediol, 2,3-heptanediol, 2,3-octanediol, 2,3-nonanediol, 2,3-decanediol, 2,3-undecanediol, 2,3-dodecanediol, 2,3-tridecanediol, or 2,3-tetradecanediol; or • A combination of 1,2-dodecanediol and one of the following: 2,3-pentanediol, 2,3-hexanediol, 2,3-heptanediol, 2,3-octanediol, 2,3-nonanediol, 2,3-decanediol, 2,3-undecanediol, 2,3-dodecanediol, 2,3-tridecanediol, or 2,3-tetradecanediol; or • A combination of 1,2-tridecanediol and one of the following: 2,3-pentanediol, 2,3-hexanediol, 2,3-heptanediol, 2,3-octanediol, 2,3-nonanediol, 2,3-decanediol, 2,3-undecanediol, 2,3-dodecanediol, 2,3-tridecanediol, or 2,3-tetradecanediol; or • A combination of 1,2-tetradecanediol and one of the following: 2,3-pentanediol, 2,3-hexanediol, 2,3-heptanediol, 2,3-octanediol, 2,3-nonanediol, 2,3-decanediol, 2,3-undecanediol, 2,3-dodecanediol, 2,3-tridecanediol, or 2,3-tetradecanediol; or • A combination of 2,3-pentanediol and one of 1,2-pentanediol, 1,2-hexanediol, 1,2-heptanediol, 1,2-octanediol, 1,2-nonanediol, 1,2-decanediol, 1,2-undecanediol, 1,2-dodecanediol, 1,2-tridecanediol, or 1,2-tetradecanediol; or • A combination of 2,3-hexanediol and one of 1,2-pentanediol, 1,2-heptanediol, 1,2-octanediol, 1,2-nonanediol, 1,2-decanediol, 1,2-undecanediol, 1,2-dodecanediol, 1,2-tridecanediol, or 1,2-tetradecanediol; or • A combination of 2,3-heptanediol and one of 1,2-pentanediol, 1,2-hexanediol, 1,2-octanediol, 1,2-nonanediol, 1,2-decanediol, 1,2-undecanediol, 1,2-dodecanediol, 1,2-tridecanediol or 1,2-tetradecanediol; or • A combination of 2,3-octanediol and one of 1,2-pentanediol, 1,2-hexanediol, 1,2-heptanediol, 1,2-nonanediol, 1,2-decanediol, 1,2-undecanediol, 1,2-dodecanediol, 1,2-tridecanediol, or 1,2-tetradecanediol; or • A combination of 2,3-nonanediol and one of 1,2-pentanediol, 1,2-hexanediol, 1,2-heptanediol, 1,2-octanediol, 1,2-decanediol, 1,2-undecanediol, 1,2-dodecanediol, 1,2-tridecanediol, or 1,2-tetradecanediol; or • A combination of 2,3-decanediol and one of 1,2-pentanediol, 1,2-hexanediol, 1,2-heptanediol, 1,2-octanediol, 1,2-nonanediol, 1,2-undecanediol, 1,2-dodecanediol, 1,2-tridecanediol, or 1,2-tetradecanediol; or • A combination of 2,3-undecanediol and one of 1,2-pentanediol, 1,2-hexanediol, 1,2-heptanediol, 1,2-octanediol, 1,2-nonanediol, 1,2-decanediol, 1,2-dodecanediol, 1,2-tridecanediol, or 1,2-tetradecanediol; or • A combination of 2,3-dodecanediol and one of 1,2-pentanediol, 1,2-hexanediol, 1,2-heptanediol, 1,2-octanediol, 1,2-nonanediol, 1,2-decanediol, 1,2-undecanediol, 1,2-tridecanediol, or 1,2-tetradecanediol; or • Combinations of 2,3-tridecanediol with one of the following: 1,2-pentanediol, 1,2-hexanediol, 1,2-heptanediol, 1,2-octanediol, 1,2-nonanediol, 1,2-decanediol, 1,2-undecanediol, 1,2-dodecanediol, or 1,2-tetradecanediol; • A combination of 2,3-tetradecanediol and one of 1,2-pentanediol, 1,2-hexanediol, 1,2-heptanediol, 1,2-octanediol, 1,2-nonanediol, 1,2-decanediol, 1,2-undecanediol, 1,2-dodecanediol, or 1,2-tridecanediol; or • A combination of 2,3-pentanediol and one of 2,3-hexanediol, 2,3-heptanediol, 2,3-octanediol, 2,3-nonanediol, 2,3-decanediol, 2,3-undecanediol, 2,3-dodecanediol, 2,3-tridecanediol, or 2,3-tetradecanediol; or • A combination of 2,3-hexanediol and one of 2,3-pentanediol, 2,3-heptanediol, 2,3-octanediol, 2,3-nonanediol, 2,3-decanediol, 2,3-undecanediol, 2,3-dodecanediol, 2,3-tridecanediol, or 2,3-tetradecanediol; or • A combination of 2,3-heptanediol and one of 2,3-pentanediol, 2,3-hexanediol, 2,3-octanediol, 2,3-nonanediol, 2,3-decanediol, 2,3-undecanediol, 2,3-dodecanediol, 2,3-tridecanediol, or 2,3-tetradecanediol; or • A combination of 2,3-octanediol and one of 2,3-pentanediol, 2,3-hexanediol, 2,3-heptanediol, 2,3-nonanediol, 2,3-decanediol, 2,3-undecanediol, 2,3-dodecanediol, 2,3-tridecanediol, or 2,3-tetradecanediol; or • A combination of 2,3-nonanediol and one of 2,3-pentanediol, 2,3-hexanediol, 2,3-heptanediol, 2,3-octanediol, 2,3-decanediol, 2,3-undecanediol, 2,3-dodecanediol, 2,3-tridecanediol, or 2,3-tetradecanediol; or • A combination of 2,3-decanediol and one of 2,3-pentanediol, 2,3-hexanediol, 2,3-heptanediol, 2,3-octanediol, 2,3-nonanediol, 2,3-undecanediol, 2,3-dodecanediol, 2,3-tridecanediol, or 2,3-tetradecanediol; or • A combination of 2,3-undecanediol and one of 2,3-pentanediol, 2,3-hexanediol, 2,3-heptanediol, 2,3-octanediol, 2,3-nonanediol, 2,3-decanediol, 2,3-dodecanediol, 2,3-tridecanediol, or 2,3-tetradecanediol; or • A combination of 2,3-dodecanediol and one of 2,3-pentanediol, 2,3-hexanediol, 2,3-heptanediol, 2,3-octanediol, 2,3-nonanediol, 2,3-decanediol, 2,3-undecanediol, 2,3-tridecanediol, or 2,3-tetradecanediol; or • A combination of 2,3-tridecanediol and one of 2,3-pentanediol, 2,3-hexanediol, 2,3-heptanediol, 2,3-octanediol, 2,3-nonanediol, 2,3-decanediol, 2,3-undecanediol, 2,3-dodecanediol, or 2,3-tetradecanediol; or • A combination of 2,3-tetradecanediol and one of the following: 2,3-pentanediol, 2,3-hexanediol, 2,3-heptanediol, 2,3-octanediol, 2,3-nonanediol, 2,3-decanediol, 2,3-undecanediol, 2,3-dodecanediol, or 2,3-tridecanediol.

[0273] In a particularly preferred modification, in the detergent and cleaning composition according to the present invention, the linear alkanediol is selected from the group consisting of 1,2-pentanediol, 1,2-hexanediol, 1,2-heptanediol, 1,2-octanediol, 1,2-nonanediol, 1,2-decanediol, 1,2-undecanediol, 1,2-dodecanediol, 1,2-tridecanediol, 1,2-tetradecanediol, and any mixture thereof.

[0274] In a more particularly preferred variation, the detergent and cleaning composition according to the present invention comprises a mixture or combination containing at least one first linear alkanediol and one or more second linear alkanediols, comprising any one of the following mixtures / combinations: • A mixture containing 1,2-pentanediol and 2,3-pentanediol; or • A mixture containing 1,2-hexanediol and 2,3-hexanediol; or • A mixture containing 1,2-heptanediol and 2,3-heptanediol; or • A mixture containing 1,2-octanediol and 2,3-octanediol; or • A mixture containing 1,2-nonanediol and 2,3-nonanediol, or • A mixture containing 1,2-decanediol and 2,3-decanediol; or • A mixture containing 1,2-undecanediol and 2,3-undecanediol; or • A mixture containing 1,2-dodecanediol and 2,3-dodecanediol; or • A mixture containing 1,2-tridecanediol and 2,3-tridecanediol; or A mixture containing 1,2-tetradecanediol and 2,3-tetradecanediol.

[0275] In the aforementioned homoalkanediol mixture, the first linear alkanediol and the second linear alkanediol have the same number of carbon atoms.

[0276] Particularly preferred are mixtures containing 1,2-pentanediol in combination with 2,3-pentanediol, or mixtures containing 1,2-heptanediol in combination with 2,3-heptanediol, or mixtures containing 1,2-octanediol in combination with 2,3-octanediol and / or 3,4-octanediol.

[0277] Due to their remarkable enzyme-stabilizing effects, homoalkanediol mixtures containing 1,2-nonanediol and 2,3-nonanediol, or homoalkanediol mixtures containing 1,2-decanediol and 2,3-decanediol, or homoalkanediol mixtures containing 1,2-undecanediol and 2,3-undecanediol are most preferred.

[0278] The specific homoalkanediol mixtures described above according to a second aspect of the present invention, comprising 1,2-alkanediols and 2,3-alkanediols, are characterized by a synergistically enhanced effect, namely, the alkanediol mixture synergistically stabilizes enzymes in detergents and cleaning compositions compared to each of their single 1,2-alkanediol or 2,3-alkanediol substances.

[0279] The aforementioned synergistic effects or actions in enzyme stabilization were observed in homomixtures containing 1,2-pentanediol and 2,3-pentanediol.

[0280] The aforementioned synergistic effect in enzyme stabilization is also observed in homomixtures containing 1,2-hexanediol and 2,3-hexanediol.

[0281] Homo-mixtures containing 1,2-heptanediol and 2,3-heptanediol are particularly beneficial because they exhibit a particularly remarkable synergistic effect on enzyme stabilization in detergents and cleaning compositions.

[0282] Alkanediol mixtures containing 1,2-octanediol and 2,3-octanediol, or alkanediol mixtures containing 1,2-nonanediol and 2,3-nonanediol, are particularly advantageous because they are effective in synergistically stabilizing enzymes in enzyme detergents and cleaning compositions.

[0283] Furthermore, an alkanediol mixture containing 1,2-decanediol and 2,3-decanediol, or an alkanediol mixture containing 1,2-undecanediol and 2,3-undecanediol, synergistically stabilizes enzymes in detergents and cleaning compositions.

[0284] The enzyme stabilization effect also applies to alkanediol mixtures containing 1,2-dodecanediol and 2,3-dodecanediol, or alkanediol mixtures containing 1,2-tridecanediol and 2,3-tridecanediol.

[0285] The aforementioned synergistic stabilizing effect on the performance of enzymes in detergents and cleaning compositions is particularly pronounced for homomixtures containing 1,2-heptanediol and 2,3-heptanediol, or homomixtures containing 1,2-octanediol and 2,3-octanediol, or homomixtures containing 1,2-nonanediol and 2,3-nonanediol.

[0286] The aforementioned specific homoalkanediol mixtures, containing 1,2-alkanediols and their corresponding 2,3-alkanediols, exhibit remarkable synergistic activity, clearly superior to the individual corresponding 1,2-alkanediols or 2,3-alkanediols, even at the same concentration.

[0287] Therefore, in a particularly preferred modification, a detergent and cleaning composition according to a second aspect of the present invention, comprising a mixture or combination of at least one first linear alkanediol and one or more second linear alkanediols, may comprise any of the following mixtures / combinations: • A mixture containing 1,2-hexanediol and 1,2-octanediol; or • A mixture containing 1,2-hexanediol and 2,3-octanediol; or • A mixture containing 1,2-octanediol and 2,3-hexanediol; or • A mixture containing 1,2-octanediol and 2,3-heptanediol; or • A mixture containing 1,2-pentanediol and 2,3-hexanediol; or • A mixture containing 1,2-pentanediol and 2,3-heptanediol; or • A mixture containing 1,2-pentanediol and 2,3-octanediol; or • A mixture containing 1,2-pentanediol and 1,2-nonanediol; or • A mixture containing 1,2-pentanediol and 2,3-nonanediol; or • A mixture containing 1,2-heptanediol and 1,2-pentanediol; or • A mixture containing 1,2-heptanediol and 1,2-hexanediol; or • A mixture containing 1,2-heptanediol and 1,2-octanediol; or • A mixture containing 1,2-heptanediol and 2,3-octanediol; or • A mixture containing 1,2-heptanediol and 1,2-nonanediol; or • A mixture containing 1,2-heptanediol and 2,3-nonanediol; or • A mixture containing 1,2-heptanediol and 1,2-decanediol; or • A mixture containing 1,2-heptanediol and 1,2-undecanediol; or • A mixture containing 1,2-heptanediol and 1,2-dodecanediol; or A mixture containing 1,2-heptanediol and 1,2-tridecanediol.

[0288] The particular alkanediol mixture according to the present invention, comprising a first linear alkanediol and a second linear alkanediol, is characterized by a synergistically enhanced effect, namely, the alkanediol mixture synergistically stabilizes enzymes in detergents and cleaning compositions compared to the corresponding individual 1,2-alkanediol or 2,3-alkanediol substances.

[0289] Therefore, in a particularly preferred modification, the detergent and cleaning composition according to the present invention, which comprises a mixture or combination containing at least one first linear alkanediol and one or more second linear alkanediols, may include the following mixtures / combinations: A mixture containing 1,2-hexanediol and 1,2-octanediol.

[0290] Surprisingly, the aforementioned alkanediol mixture exhibits a particularly remarkable enzyme-stabilizing effect.

[0291] More preferably, the enzyme stabilizer mixture comprises at least a first linear alkanediol selected from 1,2-alkanediols having 5 to 8 fewer carbon atoms, and one or more second alkanediols selected from 1,2-alkanediols having 9 to 14 more carbon atoms.

[0292] Most preferably, the enzyme stabilizer mixture comprises at least a first linear alkanediol selected from the group consisting of 1,2-pentanediol, 1,2-hexanediol, 1,2-heptanediol, 1,2-octanediol, and any mixtures thereof, and one or more second alkanediols selected from the group consisting of 1,2-nonanediol, 1,2-decanediol, 1,2-undecanediol, 1,2-dodecanediol, 1,2-tridecanediol, 1,2-tetradecanediol, and any mixtures thereof.

[0293] Most preferably, the enzyme stabilizer blend comprises at least one first linear alkanediol selected from the group consisting of 1,2-alkanediols having a lower number of carbon atoms (5 to 8), i.e., 1,2-pentanediol, 1,2-hexanediol, 1,2-heptanediol, 1,2-octanediol, and any mixtures thereof, and one or more second alkanediols selected from the group consisting of 1,2-alkanediols having a higher number of carbon atoms (9 to 13), i.e., 1,2-nonanediol, 1,2-decanediol, 1,2-undecanediol, 1,2-dodecanediol, 1,2-tridecanediol, and any mixtures thereof.

[0294] Surprisingly, such alkanediol mixtures, including short-chain and long-chain alkanediols, exhibit particularly remarkable enzyme stabilization effects.

[0295] More preferably are alkanediol mixtures in which the difference between the number of carbon atoms of at least one first linear alkanediol and the number of carbon atoms of one or more second alkanediols is at least two carbon atoms. In these alkanediol mixtures, short-chain and long-chain alkanediols combine with each other, resulting in improved enzyme stabilization.

[0296] More preferably, the enzyme stabilizer mixture is such that the difference between the number of carbon atoms of at least one first linear alkanediol and the number of carbon atoms of one or more second alkanediols is at least three carbon atoms. Such an alkanediol mixture exhibits a particularly pronounced enzyme stabilization effect.

[0297] Such combinations may include any of the following mixtures / combinations: • A combination of 1,2-pentanediol and one of 1,2-octanediol, 1,2-nonanediol, 1,2-decanediol, 1,2-undecanediol, 1,2-dodecanediol, 1,2-tridecanediol, or 1,2-tetradecanediol; or • A combination of 1,2-hexanediol and one of 1,2-nonanediol, 1,2-decanediol, 1,2-undecanediol, 1,2-dodecanediol, 1,2-tridecanediol, or 1,2-tetradecanediol; or • Combinations of 1,2-heptanediol with one of 1,2-decanediol, 1,2-undecanediol, 1,2-dodecanediol, 1,2-tridecanediol, and 1,2-tetradecanediol; and A combination of 1,2-octanediol and one of the following: 1,2-undecanediol, 1,2-dodecanediol, 1,2-tridecanediol, or 1,2-tetradecanediol.

[0298] In a more preferred variation of the present invention, in detergents and cleaning compositions, the linear alkanediol is selected from the group consisting of 2,3-pentanediol, 2,3-hexanediol, 2,3-heptanediol, 2,3-octanediol, 2,3-nonanediol, 2,3-decanediol, 2,3-undecanediol, 2,3-dodecanediol, 2,3-tridecanediol, 2,3-tetradecanediol, and mixtures thereof.

[0299] In a more preferred variation of detergents and cleaning compositions according to another aspect of the present invention, the linear alkanediol is selected from the group consisting of 2,3-pentanediol, 2,3-hexanediol, 2,3-heptanediol, 2,3-octanediol, 2,3-nonanediol, and mixtures thereof.

[0300] Surprisingly, the addition of 2,3-pentanediol, 2,3-hexanediol, 2,3-heptanediol, and other 2,3-alkanediols, such as 2,3-octanediol, 2,3-nonanediol, 2,3-decanediol, 2,3-undecanediol, 2,3-dodecanediol, 2,3-tridecanediol, and 2,3-tetradecanediol, to enzyme-containing detergents and cleaning compositions results in significant stabilization of the aforementioned enzymes compared to compositions without the addition of 2,3-alkanediols.

[0301] In a particularly preferred modification, the detergent and cleaning composition according to the present invention comprises at least one enzyme stabilizer selected from the group consisting of at least one linear 1,2-alkanediol having a carbon chain of 6 to 14 carbon atoms, or a mixture comprising at least one first linear 1,2-alkanediol having a carbon chain of 6 to 14 carbon atoms and one or more second linear 1,2-alkanediols having a carbon chain of 6 to 14 carbon atoms different from the first linear 1,2-alkanediol.

[0302] In a particularly preferred modification, the detergent and cleaning composition according to the present invention comprises at least one enzyme stabilizer selected from the group consisting of at least one linear 1,2-alkanediol having a carbon chain of 7 to 14 carbon atoms, or a mixture comprising at least one first linear 1,2-alkanediol having a carbon chain of 7 to 14 carbon atoms and one or more second linear 1,2-alkanediols having a carbon chain of 7 to 14 carbon atoms different from the first linear 1,2-alkanediol.

[0303] Surprisingly, these 1,2-alkanediols, having carbon chains of 6-14 or 7-14 carbon atoms, have been found to be particularly effective enzyme stabilizers and can be effectively incorporated into a wide range of detergent and cleaning compositions. Furthermore, the improved enzyme stability in detergents and cleaning compositions results in better cleaning performance after storage compared to detergents and cleaning compositions without such alkanediol stabilizers.

[0304] In a particularly preferred modification, the detergent and cleaning composition according to the present invention comprises at least one enzyme stabilizer selected from the group consisting of at least one linear 1,2-alkanediol having a carbon chain of 5 to 8 carbon atoms, or a mixture comprising at least one first linear 1,2-alkanediol having a carbon chain of 5 to 8 carbon atoms and one or more second linear 1,2-alkanediols having a carbon chain of 5 to 8 carbon atoms different from the first linear 1,2-alkanediol.

[0305] In a more preferred variation, the detergent and cleaning composition according to the present invention comprises at least one enzyme stabilizer selected from the group consisting of at least one linear 1,2-alkanediol having a carbon chain of 6 to 7 carbon atoms, or a mixture comprising at least one first linear 1,2-alkanediol having a carbon chain of 6 to 7 carbon atoms and one or more second linear 1,2-alkanediols having a carbon chain of 6 to 7 carbon atoms different from the first linear 1,2-alkanediol.

[0306] Surprisingly, these short-chain 1,2-alkanediols were found to be particularly suitable enzyme stabilizers and can be efficiently incorporated into a wide range of detergent and cleaning compositions. These substances exhibit remarkable enzyme-stabilizing properties, significantly slowing the rate of enzyme inactivation in detergent and cleaning compositions during storage. Such detergents and cleaning compositions exhibit improved cleaning properties compared to those without such substances.

[0307] In a particularly preferred modification, the detergent and cleaning composition according to the present invention comprises at least one enzyme stabilizer selected from the group consisting of at least one linear 1,2-alkanediol having a carbon chain of 9 to 14 carbon atoms, or a mixture comprising at least one first linear 1,2-alkanediol having a carbon chain of 9 to 14 carbon atoms and one or more second linear 1,2-alkanediols having a carbon chain of 9 to 14 carbon atoms different from the first linear 1,2-alkanediol.

[0308] In a more preferred variation, the detergent and cleaning composition according to the present invention comprises at least one enzyme stabilizer selected from the group consisting of at least one linear 1,2-alkanediol having a carbon chain of 10 to 13 carbon atoms, or a mixture comprising at least one first linear 1,2-alkanediol having a carbon chain of 10 to 13 carbon atoms and one or more second linear 1,2-alkanediols having a carbon chain of 10 to 13 carbon atoms different from the first linear alkanediol.

[0309] In a more preferred variation, the detergent and cleaning composition according to the present invention comprises at least one enzyme stabilizer selected from the group consisting of at least one linear 1,2-alkanediol having a carbon chain of 11 to 12 carbon atoms, or a mixture comprising at least one first linear 1,2-alkanediol having a carbon chain of 11 to 12 carbon atoms and one or more second linear 1,2-alkanediols having a carbon chain of 11 to 12 carbon atoms different from the first linear alkanediol.

[0310] Surprisingly, these long-chain 1,2-alkanediols were found to be particularly suitable enzyme stabilizers and can be efficiently incorporated into a wide range of detergent and cleaning compositions. These substances exhibit remarkable enzyme-stabilizing properties, significantly slowing the rate of enzyme inactivation in detergent and cleaning compositions during storage. Such detergents and cleaning compositions exhibit improved cleaning properties compared to those without such substances.

[0311] In the most preferred variation, the detergent and cleaning composition according to the present invention comprises at least one enzyme stabilizer selected from the group consisting of at least one linear 1,2-alkanediol having a log Pow value of ≤1, or a mixture comprising at least one first linear 1,2-alkanediol having a log Pow value of ≤1 and one or more second linear 1,2-alkanediols having a log Pow value of ≤1 that are different from the first linear 1,2-alkanediol.

[0312] 1,2-alkanediols having a log Pow value of ≤1 are selected from the group consisting of 1,2-pentanediol (0.06), 1,2-hexanediol (0.58), 1,2-heptanediol (0.9), and any mixture thereof. The aforementioned 1,2-alkanediols are soluble in water.

[0313] The Pow value is the partition coefficient of a compound in a two-phase system consisting of two immiscible solvents, n-octanol and water, in equilibrium. Therefore, this value represents a comparison of the solubility of the solute in these two liquids. Thus, the partition coefficient measures the degree to which a chemical substance is hydrophilic or hydrophobic.

[0314] The log Pow value is a constant defined as follows: Log Pow = log10 (distribution coefficient) Partition coefficient, P = [n-octanol] / [water] In the formula, [] indicates the concentration of the solute in the organic and / or aqueous partition. The log Pow value is determined at a standard temperature of 25°C.

[0315] A log Pow value of ≤ 1 means that the compound has a higher affinity for the aqueous phase (is more hydrophilic) and is therefore more soluble in water, while a log Pow value ≥ 1 indicates a higher concentration in the lipid phase (i.e., the compound is more lipophilic) and therefore more soluble in fatty solvents.

[0316] Surprisingly, it was found that 1,2-alkanediols with a log Pow value of ≤1 are particularly suitable enzyme stabilizers and can be efficiently incorporated into a wide range of detergent and cleaning compositions. Therefore, detergents and cleaning compositions containing 1,2-alkanediols with a log Pow value of ≤1 exhibit improved enzyme stability during storage compared to detergents and cleaning compositions without such 1,2-alkanediols.

[0317] In a more preferred variation, the detergent and cleaning composition according to the present invention comprises at least one enzyme stabilizer selected from the group consisting of at least one linear 1,2-alkanediol having a log Pow value of ≥1, or a mixture comprising at least one first linear 1,2-alkanediol having a log Pow value of ≥1 and one or more second linear 1,2-alkanediols having a log Pow value of ≥1 that are different from the first linear 1,2-alkanediol.

[0318] 1,2-alkanediols having a log Pow value of ≥1 are selected from the group consisting of 1,2-octanediol (log Pow = 2.1), 1,2-nonanediol, 1,2-decanediol, 1,2-undecanediol, 1,2-dodecanediol, 1,2-tridecanediol, 1,2-tetradecanediol, and any mixture thereof. The aforementioned 1,2-alkanediols are soluble in fatty solvents, such as n-octanol.

[0319] Surprisingly, it was found that 1,2-alkanediols having a log Pow value of ≥1 are particularly suitable enzyme stabilizers and can be efficiently incorporated into a wide range of detergent and cleaning compositions. Therefore, detergents and cleaning compositions containing 1,2-alkanediols having a log Pow value of ≥1 exhibit improved enzyme stability during storage compared to detergents and cleaning compositions without such 1,2-alkanediols.

[0320] In the context of this invention, the term "alkanediol" also includes its stereoisomers. Stereoisomers are molecules that have the same molecular formula but differ only in how their atoms are arranged in three-dimensional space. According to the definition above, the linear alkanediols of this invention, or the first linear alkanediol having a carbon chain of 5 to 14 carbon atoms, or the second linear alkanediol having a carbon chain of 5 to 14 carbon atoms, encompass the following stereoisomers, as described in detail above:

[0321] 1,2-Alkanediol stereoisomers: (2S)-pentane-1,2-diol, (2R)-pentane-1,2-diol, (2S)-hexane-1,2-diol, (2R)-hexane-1,2-diol, (2S)-heptane-1,2-diol, (2R)-heptane-1,2-diol, (2S)-Octane-1,2-diol, (2R)-Octane-1,2-diol, (2S)-Nonane-1,2-Diol, (2R)-Nonane-1,2-Diol, (2S)-decane-1,2-diol, (2R)-decane-1,2-diol, (2S)-Undecane-1,2-Diol, (2R)-Undecane-1,2-Diol, (2S)-Dodecane-1,2-diol, (2R)-Dodecane-1,2-diol, (2S)-Tridecane-1,2-diol, (2R)-Tridecane-1,2-diol, (2S)-tetradecane-1,2-diol, (2R)-tetradecane-1,2-diol,

[0322] 2,3-Alkanediol stereoisomers: (2S,3S)-pentane-2,3-diol, (2R,3R)-pentane-2,3-diol, (2S,3S)-hexane-2,3-diol, (2R,3R)-hexane-2,3-diol, (2S,3S)-heptane-2,3-diol, (2R,3R)-heptane-2,3-diol, (2S,3S)-octane-2,3-diol, (2R,3R)-octane-2,3-diol, (2S,3S)-Nonane-2,3-Diol, (2R,3R)-Nonane-2,3-Diol, (2S,3S)-decane-2,3-diol, (2R,3R)-decane-2,3-diol, (2S,3S)-Undecane-2,3-Diol, (2R,3R)-Undecane-2,3-Diol, (2S,3S)-dodecane-2,3-diol, (2R,3R)-dodecane-2,3-diol, (2S,3S)-Tridecane-2,3-diol, (2R,3R)-Tridecane-2,3-diol, (2S,3S)-tetradecane-2,3-diol, (2R,3R)-tetradecane-2,3-diol, (2S,3R)-pentane-2,3-diol, (2R,3S)-pentane-2,3-diol, (2S,3R)-hexane-2,3-diol, (2R,3S)-hexane-2,3-diol, (2S,3R)-heptane-2,3-diol, (2R,3S)-heptane-2,3-diol, (2S,3R)-octane-2,3-diol, (2R,3S)-octane-2,3-diol, (2S,3R)-nonane-2,3-diol, (2R,3S)-nonane-2,3-diol, (2S,3R)-decane-2,3-diol, (2R,3S)-decane-2,3-diol, (2S,3R)-Undecane-2,3-Diol, (2R,3S)-Undecane-2,3-Diol, (2S,3R)-dodecane-2,3-diol, (2R,3S)-dodecane-2,3-diol, (2S,3R)-tridecane-2,3-diol, (2R,3S)-tridecane-2,3-diol, (2S,3R)-tetradecane-2,3-diol, (2R,3S)-tetradecane-2,3-diol.

[0323] 3,4-Alkanediol stereoisomers: (3R,4R)-pentane-3,4-diol, (3S,4S)-pentane-3,4-diol, (3R,4R)-hexane-3,4-diol, (3S,4S)-hexane-3,4-diol, (3R,4R)-heptane-3,4-diol, (3S,4S)-heptane-3,4-diol, (3R,4R)-Octane-3,4-diol, (3S,4S)-Octane-3,4-diol, (3R,4R)-Nonane-3,4-Diol, (3S,4S)-Nonane-3,4-Diol, (3R,4R)-Decane-3,4-Diol, (3S,4S)-Decane-3,4-Diol, (3R,4R)-Undecane-3,4-Diol, (3S,4S)-Undecane-3,4-Diol, (3R,4R)-Dodecane-3,4-Diol, (3S,4S)-Dodecane-3,4-Diol, (3R,4R)-Tridecane-3,4-diol, (3S,4S)-Tridecane-3,4-diol, (3R,4R)-tetradecane-3,4-diol, (3S,4S)-tetradecane-3,4-diol, (3R,4S)-pentane-3,4-diol, (3S,4R)-pentane-3,4-diol, (3R,4S)-hexane-3,4-diol, (3S,4R)-hexane-3,4-diol, (3R,4S)-heptane-3,4-diol, (3S,4R)-heptane-3,4-diol, (3R,4S)-octane-3,4-diol, (3S,4R)-octane-3,4-diol, (3R,4S)-Nonane-3,4-Diol, (3S,4R)-Nonane-3,4-Diol, (3R,4S)-decane-3,4-diol, (3S,4R)-decane-3,4-diol, (3R,4S)-Undecane-3,4-Diol, (3S,4R)-Undecane-3,4-Diol, (3R,4S)-dodecane-3,4-diol, (3S,4R)-dodecane-3,4-diol, (3R,4S)-tridecane-3,4-diol, (3S,4R)-tridecane-3,4-diol, (3R,4S)-tetradecane-3,4-diol, (3S,4R)-tetradecane-3,4-diol.

[0324] In the context of this specification, the terms “1,2-diol,” “2,3-diol,” or “3,4-diol” include both the corresponding S-configuration enantiomer and R-enantiomer, as well as any mixture of these S and R-configuration enantiomers, i.e., a mixture of racemic mixtures of each diol.

[0325] The alkanediol mixture of detergents and cleaning compositions according to the first aspect of the present invention contains 1,2-heptanediol and 2,3-heptanediol in a ratio in the range of 50:50 to 99.9:0.1, preferably in the range of 75:25 to 99:1, more preferably in the range of 80:20 to 98:2, or even more preferably in the range of 90:10 to 95:5.

[0326] In the detergent and cleaning composition according to the first aspect of the present invention, 1,2-heptanediol and 2,3-heptanediol are contained in the mixture in a ratio preferably in the range of 98:2 to 99.9:0.1.

[0327] In the detergent and cleaning composition according to the first aspect of the present invention, 1,2-heptanediol and 2,3-heptanediol are included in the alkanediol mixture in a ratio preferably in the range of 95:5 to 99.9:0.1.

[0328] Preferably, 1,2-heptanediol and 2,3-heptanediol are included in the mixture of detergents and cleaning compositions according to the first embodiment of the present invention in a ratio of ≥95:≤5, more preferably ≥96:≤4, even more preferably ≥97:≤3, and most preferably ≥98:≤2.

[0329] The majority of the mixture of detergents and cleaning compositions according to the first aspect of the present invention contains 1,2-heptanediol and 2,3-heptanediol in a ratio of ≥95:≤5, including ratios of ≥95.5:≤4.5; ≥96:≤4; ≥96.5:≤3.5; ≥97:≤3; ≥97.5:2.5 and ≥98.0:≤2.0.

[0330] More preferably, the alkanediol mixture of the detergent and cleaning composition according to the first aspect of the present invention has 1,2-heptanediol and 2,3-heptanediol in a ratio of ≥98:≤2, such that ≥98.1:≤1.9; ≥98.2:≤1.8; ≥98.3:≤1.7; ≥98.4:≤1.6; ≥98.5:≤1.5; ≥98.6:≤1.4; The ratios include those of ≥98.7:≦1.3; ≥98.8:≦1.2; ≥98.9:≦1.1; ≥99:≦1.0; ≥99.1:≦0.9; ≥99.2:≦0.8, ≥99.3:≦0.7; ≥99.4:≦0.6; ≥99.5:≦0.5; ≥99.6:≦0.4; ≥99.7:≦0.3; ≥99.8:≦0.2 and ≥99.9:≦0.1.

[0331] The first linear alkanediol and the second linear alkanediol, as defined in detail above, are present in the alkanediol mixture according to other embodiments of the present invention in a ratio in the range of 50:50 to 99.9:0.1, preferably in the range of 75:25 to 99:1, more preferably in the range of 80:20 to 98:2, and even more preferably in the range of 90:10 to 95:5.

[0332] In detergents and cleaning compositions according to other embodiments of the present invention, the first linear alkanediol and the second linear alkanediol are preferably present in the mixture in a ratio of 98:2 to 99.9:0.1.

[0333] In detergents and cleaning compositions according to other embodiments of the present invention, the first linear alkanediol and the second alkanediol are contained in the alkanediol mixture in a ratio preferably in the range of 95:5 to 99.9:0.1.

[0334] Preferably, the first linear alkanediol and the second alkanediol are included in the mixture of detergents and cleaning compositions according to other embodiments of the present invention in a ratio of ≥95:≤5, more preferably ≥96:≤4, even more preferably ≥97:≤3, and most preferably ≥98:≤2.

[0335] Most of the mixtures of detergents and cleaning compositions according to other embodiments of the present invention contain a first linear alkanediol and a second linear alkanediol in a ratio of ≥95:≤5, including ratios of ≥95.5:≤4.5; ≥96:≤4; ≥96.5:≤3.5; ≥97:≤3; ≥97.5:2.5 and ≥98.0:≤2.0.

[0336] More preferably, the majority of the alkanediol mixtures of detergents and cleaning compositions according to other embodiments of the present invention have a ratio of ≥98:≤2 between the first linear alkanediol and the second alkanediol, such that ≥98.1:≤1.9; ≥98.2:≤1.8; ≥98.3:≤1.7; ≥98.4:≤1.6; ≥98.5:≤1.5; ≥98.6:≤1.4 The ratios include the following: ≧98.7:≦1.3;≧98.8:≦1.2;≧98.9:≦1.1;≧99:≦1.0;≧99.1:≦0.9;≧99.2:≦0.8, ≧99.3:≦0.7;≧99.4:≦0.6;≧99.5:≦0.5;≧99.6:≦0.4;≧99.7:≦0.3;≧99.8:≦0.2 and ≧99.9:≦0.1.

[0337] Alternatively, the aforementioned range of ratios of the first and second alkanediols can be switched so that the second alkanediol is the main component and the first alkanediol is the minor component.

[0338] In other advantageous modifications according to other aspects of the present invention, the alkanediol mixture may be a 1,2-alkanediol, such as 1,2-pentanediol, 1,2-hexanediol, 1,2-heptanediol, 1,2-octanediol, 1,2-nonanediol, 1,2-decanediol, 1,2-undecanediol, 1,2-dodecanediol, 1,2-tridecanediol, or 1,2-tetradecanediol, as the first linear alkanediol, and the corresponding 2,3-alkanediol as the second linear alkanediol. For example, it contains 2,3-pentanediol, 2,3-hexanediol, 2,3-heptanediol, 2,3-octanediol, 2,3-nonanediol, 2,3-decanediol, 2,3-undecanediol, 2,3-dodecanediol, 2,3-tridecanediol, or 2,3-tetradecanediol in a ratio in the range of 50:50 to 99.9:0.1, preferably in the range of 75:25 to 99:1, more preferably in the range of 80:20 to 98:2, and even more preferably in the range of 90:10 to 95:5.

[0339] In a more advantageous variation of the present invention, the alkanediol mixture includes a 1,2-alkanediol as the first linear alkanediol, such as 1,2-hexanediol, 1,2-heptanediol, 1,2-octanediol, 1,2-nonanediol, 1,2-decanediol, 1,2-undecanediol, 1,2-dodecanediol, 1,2-tridecanediol, or 1,2-tetradecanediol, and a corresponding 2,3-alkanediol as the second linear alkanediol. For example, it contains 2,3-hexanediol, 2,3-heptanediol, 2,3-octanediol, 2,3-nonanediol, 2,3-decanediol, 2,3-undecanediol, 2,3-dodecanediol, 2,3-tridecanediol, or 2,3-tetradecanediol in a ratio in the range of 50:50 to 99.9:0.1, preferably in the range of 75:25 to 99:1, more preferably in the range of 80:20 to 98:2, and even more preferably in the range of 90:10 to 95:5.

[0340] Similarly, for the aforementioned alkanediol mixture, the ratio of the first linear alkanediol to the second alkanediol, or the range of such ratios, is also applicable.

[0341] In a more advantageous variation, according to a second aspect of the present invention, the alkanediol mixture comprises a 2,3-alkanediol, such as 2,3-pentanediol, 2,3-hexanediol, 2,3-heptanediol, 2,3-octanediol, 2,3-nonanediol, 2,3-decanediol, 2,3-undecanediol, 2,3-dodecanediol, 2,3-tridecanediol, or 2,3-tetradecanediol as the first linear alkanediol, and the corresponding 1,2-alkanediol as the second linear alkanediol. The mixture contains an ol, such as 1,2-pentanediol, 1,2-hexanediol, 1,2-heptanediol, 1,2-octanediol, 1,2-nonanediol, 1,2-decanediol, 1,2-undecanediol, 1,2-dodecanediol, 1,2-tridecanediol, or 1,2-tetradecanediol, in a ratio in the range of 50:50 to 99.9:0.1, preferably in the range of 75:25 to 99:1, more preferably in the range of 80:20 to 98:2, and even more preferably in the range of 90:10 to 95:5.

[0342] In a more advantageous variation of the present invention, the alkanediol mixture includes a 2,3-alkanediol as the first linear alkanediol, such as 2,3-hexanediol, 2,3-heptanediol, 2,3-octanediol, 2,3-nonanediol, 2,3-decanediol, 2,3-undecanediol, 2,3-dodecanediol, 2,3-tridecanediol, or 2,3-tetradecanediol, and a corresponding 1,2-alkanediol as the second linear alkanediol. For example, it contains 1,2-hexanediol, 1,2-heptanediol, 1,2-octanediol, 1,2-nonanediol, 1,2-decanediol, 1,2-undecanediol, 1,2-dodecanediol, 1,2-tridecanediol, or 1,2-tetradecanediol in a ratio in the range of 50:50 to 99.9:0.1, preferably in the range of 75:25 to 99:1, more preferably in the range of 80:20 to 98:2, and even more preferably in the range of 90:10 to 95:5.

[0343] Similarly, for the aforementioned alkanediol mixture, the ratio of the first linear alkanediol to the second alkanediol, or the range of such ratios, is also applicable.

[0344] A more advantageous variation of the present invention includes an alkanediol mixture comprising a combination of a 1,2-alkanediol as a first linear alkanediol and a corresponding 2,3-alkanediol as a second linear alkanediol, for example, 1,2-pentanediol and 2,3-pentanediol, or 1,2-Hexanediol and 2,3-Hexanediol, or 1,2-heptanediol and 2,3-heptanediol, or 1,2-octanediol and 2,3-octanediol, or 1,2-nonanediol and 2,3-nonanediol, or 1,2-decanediol and 2,3-decanediol, or 1,2-Undecanediol and 2,3-Undecanediol, or 1,2-Dodecanediol and 2,3-Dodecanediol, or 1,2-Tridecanediol and 2,3-Tridecanediol, or 1,2-tetradecanediol and 2,3-tetradecanediol, The first linear alkanediol and the second linear alkanediol exist in a ratio in the range of 50:50 to 99.9:0.1, preferably in the range of 75:25 to 99:1, more preferably in the range of 80:20 to 98:90:2, and even more preferably in the range of 10 to 95:5.

[0345] Similarly, for the aforementioned alkanediol mixture, the ratio of the first linear alkanediol to the second alkanediol, or the range of such ratios, is also applicable.

[0346] Preferred variations according to the present invention also include mixtures comprising 1,2-hexanediol as the first linear alkanediol and 1,2-octanediol as the second linear alkanediol in any ratio in the range of 50:50 to 99.9:0.1, preferably in the range of 75:25 to 99:1, more preferably in the range of 80:20 to 98:2, or even more preferably in the range of 90:10 to 95:5.

[0347] Therefore, according to another preferred modification, the present invention relates to detergents and cleaning compositions, (i) A mixture containing 1,2-heptanediol and 2,3-heptanediol contains 1,2-heptanediol and 2,3-heptanediol in a ratio in the range of 50:50 to 99.9:0.1, preferably in the range of 75:25 to 99:1, more preferably in the range of 80:20 to 98:2, and even more preferably in the range of 90:10 to 95:5; or (ii) The present invention relates to detergents and cleaning compositions comprising a mixture containing at least one first linear alkanediol and one or more second linear alkanediols, wherein the first linear alkanediol and the second alkanediol are in a ratio in the range of 50:50 to 99.9:0.1, preferably in the range of 75:25 to 99:1, more preferably in the range of 80:20 to 98:2, and even more preferably in the range of 90:10 to 95:5.

[0348] These mixing ratios result in the aforementioned mixture exhibiting synergistic enzyme stabilization activity in enzyme-containing detergents and cleaning compositions, compared directly to the corresponding individual alkanediols.

[0349] Alkanediols are obtained by synthesis from petrochemical or other fossil fuel sources by known methods such as olefin bishydroxylation, hydrolysis from epoxides, or various chemical transformations, as described in U.S. Patent Application Publication No. 2019 / 0241491 and U.S. Patent Application Publication No. 2020 / 0189995, or from bio-derived raw materials by fermentation, or from bio-based natural and renewable raw materials such as biomass by catalytic synthesis. The alkanediols used in accordance with the present invention include either petrochemically derived alkanediols or alkanediols derived from bio-based natural and renewable raw materials. Preferably, the alkanediols are from bio-based sources and are therefore bioalkanediols.

[0350] In addition to the specific alkanediols mentioned above, the enzyme stabilizers for detergents and cleaning compositions according to the second aspect of the present invention include (b II ) Glyceryl caprylate, or (b III )4-hydroxyacetophenone, or (b IV ) Ethylhexylglycerin, or (b V ) Tropolone, or any mixture of the aforementioned drugs.

[0351] Glyceryl caprylate (b II )

[0352] [ka] It is a natural emollient derived from glycerin and plant fatty acids, and usually appears as a white, waxy solid. This ingredient is used in many skincare products due to its emollient and moisturizing properties to help maintain the moisture balance in the skin. In addition, glyceryl caprylate (b II ) is used as an antimicrobial active ingredient in cosmetic preparations.

[0353] Surprisingly, glyceryl caprylate, an oily surfactant coemulsifier, was found to be another suitable enzyme stabilizer within the scope of the present invention.

[0354] 4-Hydroxyacetophenone (4-HAP)(b III )

[0355] [ka] It possesses antioxidant, fungicidal, and bacterial growth inhibitory properties, and is therefore used to stabilize cosmetic preparations.

[0356] Surprisingly, 4-HAP was found to be another suitable enzyme stabilizer within the scope of the present invention.

[0357] Ethylhexylglycerin (EHG) (b IV )

[0358] [ka] Ethylhexylglycerin (EHG or octoxyglycerin) is a relatively new cosmetic ingredient used for its surfactant, dispersion, skin softening, skin conditioning, and antimicrobial properties. Ethylhexylglycerin is a glyceryl ether and vicinal diol.

[0359] Surprisingly, EHG was found to be suitable for stabilizing enzymes in detergents and cleaning compositions within the scope of the present invention.

[0360] Tropolone (b V )

[0361] [ka] It is known for its antibacterial, antifungal, anti-inflammatory, antioxidant, and chelating properties, and is therefore used in cosmetic formulations.

[0362] Surprisingly, troporon was found to act as an enzyme stabilizer in detergents and cleaning compositions within the scope of the present invention.

[0363] The above-mentioned specific enzyme stabilizers (b II )(b III ), (b IV ) and (b V ) may be used in detergents and cleaning compositions either individually or in the form of a mixture of two or more enzyme stabilizers.

[0364] In a particularly preferred modification, at least one enzyme stabilizer (b) in the detergent and cleaning composition according to the present invention comprises one of the following mixtures / combinations: ·(b II ) Glyceryl caprylate and (b III A mixture containing 4-hydroxyacetophenone; ·(b II ) Glyceryl caprylate and (b IV A mixture containing ethylhexylglycerin; ·(b II ) Glyceryl caprylate and (b V A mixture containing tropolone; ·(b III )4-hydroxyacetophenone and (b IV A mixture containing ethylhexylglycerin; ·(b III )4-hydroxyacetophenone and (b V ) A mixture containing tropolone; and ·-(b IV ) Ethylhexylglycerin and (b V A mixture containing tropolone.

[0365] Regarding the aforementioned enhancer mixture, even a synergistic enzyme stabilization effect may be observed.

[0366] Similarly, and more preferably, the specific single enzyme stabilizer described above (b II )(b III ), (b IV ) and (b V ) or two or three enzyme stabilizers (b II )(b III ), (b IV ) and (b V ) also includes one or two or more alkanediol enzyme stabilizers as defined herein (b I A mixture of ) can be used in detergents and cleaning compositions. Preferably, such a mixture contains two or more enzyme stabilizers as defined herein.

[0367] In a particularly preferred modification, the detergent and cleaning composition according to the present invention comprises any of the following enzyme stabilizer mixtures / combinations: ·(b I ) A mixture comprising at least one linear alkanediol having a carbon chain of 5 to 14 carbon atoms as defined above, or at least one first linear alkanediol having a carbon chain of 5 to 14 carbon atoms and one or more second linear alkanediols having carbon chains of 5 to 14 carbon atoms different from the first linear alkanediol, and (b II ) A mixture containing glyceryl caprylate; ·(b I ) A mixture comprising at least one linear alkanediol having a carbon chain of 5 to 14 carbon atoms as defined above, or at least one first linear alkanediol having a carbon chain of 5 to 14 carbon atoms and one or more second linear alkanediols having carbon chains of 5 to 14 carbon atoms different from the first linear alkanediol, and (b III A mixture containing 4-hydroxyacetophenone; ·(b I)As defined above, at least one linear alkanediol having a carbon chain of 5 to 14 carbon atoms, or at least one first linear alkanediol having a carbon chain of 5 to 14 carbon atoms and one or more second linear alkanediols having a carbon chain of 5 to 14 carbon atoms different from the first linear alkanediol, and (b IV )A mixture containing ethylhexyl glycerin; ·(b I )As defined above, at least one linear alkanediol having a carbon chain of 5 to 14 carbon atoms, or at least one first linear alkanediol having a carbon chain of 5 to 14 carbon atoms and one or more second linear alkanediols having a carbon chain of 5 to 14 carbon atoms different from the first linear alkanediol, and (b V )A mixture containing tropolone.

[0368] In a preferred variant, the detergents and cleaning compositions according to the invention contain any of the following enzyme stabilizer mixtures / combinations selected from the group consisting of: ·(b II )A mixture containing glyceryl caprylate and 1,2 - pentanediol; ·(b II )A mixture containing glyceryl caprylate and 1,2 - hexanediol; ·(b II )A mixture containing glyceryl caprylate and 1,2 - heptanediol; ·(b II )A mixture containing glyceryl caprylate and 1,2 - octanediol; ·(b II )A mixture containing glyceryl caprylate and 1,2 - nonanediol; ·(b II )A mixture containing glyceryl caprylate and 1,2 - decanediol; ·(b II )A mixture containing glyceryl caprylate and 1,2 - undecanediol; ·(b II)A mixture containing glyceryl caprylate and 1,2-dodecanediol; ·(b II )A mixture containing glyceryl caprylate and 1,2-tridecanediol; ·(b II )A mixture containing glyceryl caprylate and 1,2-tetradecanediol; ·(b III )A mixture containing 4-hydroxyacetophenone and 1,2-pentanediol; ·(b III )A mixture containing 4-hydroxyacetophenone and 1,2-hexanediol; ·(b III )A mixture containing 4-hydroxyacetophenone and 1,2-heptanediol; ·(b III )A mixture containing 4-hydroxyacetophenone and 1,2-octanediol; ·(b III )A mixture containing 4-hydroxyacetophenone and 1,2-nonanediol; ·(b III )A mixture containing 4-hydroxyacetophenone and 1,2-decanediol; ·(b III )A mixture containing 4-hydroxyacetophenone and 1,2-undecanediol; ·(b III )A mixture containing 4-hydroxyacetophenone and 1,2-dodecanediol; ·(b III )A mixture containing 4-hydroxyacetophenone and 1,2-tridecanediol; ·(b III )A mixture containing 4-hydroxyacetophenone and 1,2-tetradecanediol; ·(b IV )A mixture containing ethylhexylglycerin and 1,2-pentanediol; ·(b IV )A mixture containing ethylhexylglycerin and 1,2-hexanediol; ·(b IV )A mixture containing ethylhexylglycerin and 1,2-heptanediol; ·(b IV A mixture containing ethylhexylglycerin and 1,2-octanediol; ·(b IV A mixture containing ethylhexylglycerin and 1,2-nonanediol; ·(b IV A mixture containing ethylhexylglycerin and 1,2-decanediol; ·(b IV A mixture containing ethylhexylglycerin and 1,2-undecanediol; ·(b IV A mixture containing ethylhexylglycerin and 1,2-dodecanediol; ·(b IV A mixture containing ethylhexylglycerin and 1,2-tridecanediol; ·(b IV A mixture containing ethylhexylglycerin and 1,2-tetradecanediol; ·(b V ) A mixture containing tropolone and 1,2-pentanediol; ·(b V ) A mixture containing tropolone and 1,2-hexanediol; ·(b V A mixture containing tropolone and 1,2-heptanediol; ·(b V A mixture containing tropolone and 1,2-octanediol; ·(b V ) A mixture containing tropolone and 1,2-nonanediol; ·(b V ) A mixture containing tropolone and 1,2-decanediol; ·(b V ) A mixture containing tropolone and 1,2-undecanediol; ·(b V ) A mixture containing tropolone and 1,2-dodecanediol; ·(b V A mixture containing tropolone and 1,2-tridecanediol; ·(b VA mixture containing tropolone and 1,2-tetradecanediol.

[0369] Surprisingly, the specific combination described above was found to be a particularly effective enzyme stabilizer. Subsequently, the improved enzyme stability in detergents and cleaning compositions results in better cleaning performance, even after storage, compared to detergents and cleaning compositions without such enzyme stabilizer mixtures.

[0370] Surprisingly, with respect to the aforementioned mixture, even a synergistic enzyme stabilization effect can be observed compared to the stabilization effect of a single enzyme stabilizer.

[0371] Most preferably, the detergent and cleaning composition according to the present invention comprises a mixture of enzyme stabilizers containing a 1,2-alkanediol combined with 4-hydroxyacetophenone selected from the group consisting of: ·(b III A mixture containing 4-hydroxyacetophenone and 1,2-pentanediol; ·(b III A mixture containing 4-hydroxyacetophenone and 1,2-hexanediol; ·(b III A mixture containing 4-hydroxyacetophenone and 1,2-heptanediol; ·(b III A mixture containing 4-hydroxyacetophenone and 1,2-octanediol; ·(b III A mixture containing 4-hydroxyacetophenone and 1,2-nonanediol; ·(b III A mixture containing 4-hydroxyacetophenone and 1,2-decanediol; ·(b III A mixture containing 4-hydroxyacetophenone and 1,2-undecanediol; ·(b III A mixture containing 4-hydroxyacetophenone and 1,2-dodecanediol; ·(b IIIA mixture containing 4-hydroxyacetophenone and 1,2-tridecanediol; ·(b III A mixture containing 4-hydroxyacetophenone and 1,2-tetradecanediol;

[0372] An enzyme stabilizer mixture containing 4-hydroxyacetophenone in combination with a 1,2-alkanediol was found to exhibit a remarkable synergistic enzyme stabilization effect, significantly slowing the rate of enzyme inactivation in detergents and cleaning compositions during storage. Such detergents and cleaning compositions exhibit improved cleaning properties compared to those without such enzyme stabilizing mixtures.

[0373] Particularly significant stabilizing effects were observed when the aforementioned enzyme-stabilizing mixture containing 4-hydroxyacetophenone was added to detergents and cleaning compositions containing amylase.

[0374] However, particularly significant enzyme stabilization effects can be observed with the following enzyme stabilizers: • 1,2-pentanediol; • 1,2-Hexanediol; • 1,2-heptanediol; • 1,2-octanediol; • 1,2-nonanediol; • 1,2-decanediol; • 1,2-Undecanediol; • 1,2-dodecanediol; • 1,2-dodecanediol; • 1,2-tetradecanediol; Glyceryl caprylate; ·4-hydroxyacetophenone; Ethylhexylglycerin; • Tropolone; • A mixture containing 1,2-hexanediol and 1,2-octanediol; • A mixture containing 1,2-hexanediol, 1,2-octanediol, and tropolone; and A mixture containing 4-hydroxyacetophenone and 1,2-octanediol.

[0375] With respect to detergents and cleaning compositions according to the present invention, the list of enzyme stabilizers (b1, b2, b3, b) specified herein may be optionally combined with the list of enzymes specified herein.

[0376] In a particularly advantageous modification, the detergent and cleaning composition according to the present invention comprises one of the following combinations of components (a) and (b): • Protease + one or more of the following enzyme stabilizers: (b I ) A mixture comprising at least one linear alkanediol having a carbon chain of 5 to 14 carbon atoms as defined above, or at least one first linear alkanediol having a carbon chain of 5 to 14 carbon atoms and one or more second linear alkanediols having a carbon chain of 5 to 14 carbon atoms different from the first linear alkanediol; (b II ) Glyceryl caprylate; (b III )4-hydroxyacetophenone; (b IV ) Ethylhexylglycerin; or (b V ) Tropolon; or • Lipase + one or more of the following enzyme stabilizers: (b I ) A mixture comprising at least one linear alkanediol having a carbon chain of 5 to 14 carbon atoms as defined above, or at least one first linear alkanediol having a carbon chain of 5 to 14 carbon atoms and one or more second linear alkanediols having a carbon chain of 5 to 14 carbon atoms different from the first linear alkanediol; (b II ) Glyceryl caprylate; (b III )4-hydroxyacetophenone; (b IV ) Ethylhexylglycerin; or (b V ) Tropolon; or • Amylase + one or more of the following enzyme stabilizers: (b I) A mixture comprising at least one linear alkanediol having a carbon chain of 5 to 14 carbon atoms as defined above, or at least one first linear alkanediol having a carbon chain of 5 to 14 carbon atoms and one or more second linear alkanediols having a carbon chain of 5 to 14 carbon atoms different from the first linear alkanediol; (b II ) Glyceryl caprylate; (b III )4-hydroxyacetophenone; (b IV ) Ethylhexylglycerin; or (b V ) Tropolon; or • Cellulase + one or more of the following enzyme stabilizers: (b I ) A mixture comprising at least one linear alkanediol having a carbon chain of 5 to 14 carbon atoms as defined above, or at least one first linear alkanediol having a carbon chain of 5 to 14 carbon atoms and one or more second linear alkanediols having a carbon chain of 5 to 14 carbon atoms different from the first linear alkanediol; (b II ) Glyceryl caprylate; (b III )4-hydroxyacetophenone; (b IV ) Ethylhexylglycerin; or (b V ) Tropolon; or • Mannanase + one or more of the following enzyme stabilizers: (b I ) A mixture comprising at least one linear alkanediol having a carbon chain of 5 to 14 carbon atoms as defined above, or at least one first linear alkanediol having a carbon chain of 5 to 14 carbon atoms and one or more second linear alkanediols having a carbon chain of 5 to 14 carbon atoms different from the first linear alkanediol; (b II ) Glyceryl caprylate; (b III )4-hydroxyacetophenone; (b IV ) Ethylhexylglycerin; or (b V ) Tropolon; or • Pectin lyase + one or more of the following enzyme stabilizers: (b I) A mixture comprising at least one linear alkanediol having a carbon chain of 5 to 14 carbon atoms as defined above, or at least one first linear alkanediol having a carbon chain of 5 to 14 carbon atoms and one or more second linear alkanediols having a carbon chain of 5 to 14 carbon atoms different from the first linear alkanediol; (b II ) Glyceryl caprylate; (b III )4-hydroxyacetophenone; (b IV ) Ethylhexylglycerin; or (b V ) Tropolon.

[0377] In a more preferred variation, detergents and cleaning compositions according to a second aspect of the present invention include one of the following combinations of components (a) and (b): • Protease + 1,2-pentanediol; • Protease + 1,2-hexanediol; • Protease + 1,2-heptanediol; • Protease + 1,2-octanediol; • Protease + Glyceryl Caprylate; • Protease + 4-hydroxyacetophenone; • Protease + ethylhexylglycerin; • Protease + tropolone; • A mixture containing protease, 1,2-hexanediol, and 1,2-octanediol; • A mixture containing protease, 1,2-hexanediol, 1,2-octanediol, and tropolone; • A mixture containing protease + 4-hydroxyacetophenone and 1,2-alkanediols, such as 1,2-hexanediol, 1,2-heptanediol, 1,2-octanediol, 1,2-nonanediol, 1,2-decanediol, 1,2-undecanediol, 1,2-dodecanediol, 1,2-tridecanediol, or 1,2-tetradecanediol; • Amylase + 1,2-pentanediol; • Amylase + 1,2-Hexanediol; • Amylase + 1,2-heptanediol; • Amylase + 1,2-octanediol; • Amylase + Glyceryl Caprylate; Amylase + 4-hydroxyacetophenone; • Amylase + Ethylhexylglycerin; • Amylase + Tropolone; • A mixture containing amylase, 1,2-hexanediol, and 1,2-octanediol; • A mixture containing amylase, 1,2-hexanediol, 1,2-octanediol, and tropolone; • Amylase + 4-hydroxyacetophenone and a mixture containing 1,2-alkanediols, such as 1,2-hexanediol, 1,2-heptanediol, 1,2-octanediol, 1,2-nonanediol, 1,2-decanediol, 1,2-undecanediol, 1,2-dodecanediol, 1,2-tridecanediol, or 1,2-tetradecanediol; • Lipase + 1,2-pentanediol; • Lipase + 1,2-hexanediol; • Lipase + 1,2-heptanediol; • Lipase + 1,2-octanediol; • Lipase + Glyceryl Caprylate; • Lipase + 4-hydroxyacetophenone; • Lipase + ethylhexylglycerin; • Lipase + tropolone; • A mixture containing alipase, 1,2-hexanediol, and 1,2-octanediol; • A mixture containing lipase, 1,2-hexanediol, 1,2-octanediol, and tropolone; • A mixture containing lipase + 4-hydroxyacetophenone and 1,2-alkanediols, such as 1,2-hexanediol, 1,2-heptanediol, 1,2-octanediol, 1,2-nonanediol, 1,2-decanediol, 1,2-undecanediol, 1,2-dodecanediol, 1,2-tridecanediol, or 1,2-tetradecanediol; • Mannanase + 1,2-pentanediol; • Mannanase + 1,2-hexanediol; • Mannanase + 1,2-heptanediol; • Mannanase + 1,2-octanediol; Mannanase + Glyceryl Caprylate; Mannanase + 4-hydroxyacetophenone; Mannanase + ethylhexylglycerin; • Mannanase + Tropolone; • A mixture containing mannanase, 1,2-hexanediol, and 1,2-octanediol; • A mixture containing mannanase, 1,2-hexanediol, 1,2-octanediol, and tropolone; A mixture containing mannanase + 4-hydroxyacetophenone and 1,2-alkanediols, such as 1,2-hexanediol, 1,2-heptanediol, 1,2-octanediol, 1,2-nonanediol, 1,2-decanediol, 1,2-undecanediol, 1,2-dodecanediol, 1,2-tridecanediol, or 1,2-tetradecanediol; • Pectin lyase + 1,2-pentanediol; • Pectinate lyase + 1,2-hexanediol; • Pectin lyase + 1,2-heptanediol; • Pectin lyase + 1,2-octanediol; • Pectin lyase + glyceryl caprylate; • Pectin lyase + 4-hydroxyacetophenone; • Pectin lyase + ethylhexylglycerin; Pectin lyase + tropolone; • A mixture containing pectin lyase, 1,2-hexanediol, and 1,2-octanediol; • A mixture containing pectin lyase + 1,2-hexanediol and 1,2-octanediol and tropolone; or A mixture comprising pectin lyase + 4-hydroxyacetophenone and 1,2-alkanediols, such as 1,2-hexanediol, 1,2-heptanediol, 1,2-octanediol, 1,2-nonanediol, 1,2-decanediol, 1,2-undecanediol, 1,2-dodecanediol, 1,2-tridecanediol, or 1,2-tetradecanediol.

[0378] Particularly preferred is the use of any enzyme stabilizer mixture in detergents and cleaning compositions containing amylase selected from the group consisting of: 4-hydroxyacetophenone and 1,2-pentanediol, 4-hydroxyacetophenone and 1,2-hexanediol, 4-hydroxyacetophenone and 1,2-heptanediol, 4-hydroxyacetophenone and 1,2-octanediol, 4-hydroxyacetophenone and 1,2-nonanediol, 4-hydroxyacetophenone and 1,2-decanediol, 4-hydroxyacetophenone and 1,2-undecanediol, 4-hydroxyacetophenone and 1,2-dodecanediol, 4-Hydroxy-1,2-tridecanediol or 1,2-tetradecanediol.

[0379] Particularly preferred is the use of any enzyme stabilizer mixture in detergents and cleaning compositions containing a mannanase selected from the group consisting of: 4-hydroxyacetophenone and 1,2-pentanediol, 4-hydroxyacetophenone and 1,2-hexanediol, 4-hydroxyacetophenone and 1,2-heptanediol, 4-hydroxyacetophenone and 1,2-octanediol, 4-hydroxyacetophenone and 1,2-nonanediol, 4-hydroxyacetophenone and 1,2-decanediol, 4-hydroxyacetophenone and 1,2-undecanediol, 4-hydroxyacetophenone and 1,2-dodecanediol, 4-Hydroxy-1,2-tridecanediol or 1,2-tetradecanediol.

[0380] In a more preferred variation, the detergent and cleaning composition of the present invention comprises one of the following combinations of components (a) and (b): • Protease + 1,2-hexanediol; • Protease + 1,2-heptanediol; • Protease + 1,2-octanediol; • Protease + 1,2-nonanediol; • Protease + 1,2-decanediol; • Protease + 1,2-undecanediol; • Protease + 1,2-dodecanediol; • Protease + 1,2-tridecanediol; • Protease + 1,2-tetradecanediol; • Amylase + 1,2-nonanediol; • Amylase + 1,2-decanediol; • Amylase + 1,2-undecanediol; • Amylase + 1,2-dodecanediol; • Amylase + 1,2-Tridecanediol; • Amylase + 1,2-tetradecanediol; • Lipase + 1,2-nonanediol; • Lipase + 1,2-decanediol; • Lipase + 1,2-undecanediol; • Lipase + 1,2-dodecanediol; • Lipase + 1,2-tridecanediol; • Lipase + 1,2-tetradecanediol; • Mannanase + 1,2-nonanediol; • Mannanase + 1,2-decanediol; • Mannanase + 1,2-undecanediol; • Mannanase + 1,2-dodecanediol; • Mannanase + 1,2-tridecanediol; • Mannanase + 1,2-tetradecanediol; • Pectin lyase + 1,2-nonanediol; • Pectin lyase + 1,2-decanediol; • Pectin lyase + 1,2-undecanediol; Pectin lyase + 1,2-dodecanediol; • Pectin lyase + 1,2-tridecanediol; or Pectin lyase + 1,2-tetradecanediol.

[0381] The above-mentioned specific combinations of enzymes and enzyme stabilizers have been found to provide excellent enzyme stability in detergents and cleaning compositions during storage.

[0382] Surfactants / ingredients (c1, c2, c3, c) The detergent and cleaning composition according to the present invention comprises at least one surfactant (c1, c2, c3, c).

[0383] Surfactants are added for many reasons, primarily for their cleaning and surfactant properties. They remove dirt from clothing and surfaces during the washing and cleaning process, keeping it suspended in the cleaning solution. Some surfactants also perform other functions, such as anti-foaming.

[0384] The detergents and cleaning compositions according to the present invention may contain any type of surfactant, namely anionic surfactants, cationic surfactants, nonionic surfactants, amphoteric / zwitterionic surfactants, and any mixture thereof.

[0385] Suitable surfactants that can be incorporated into the detergent and cleaning composition according to the present invention are as follows:

[0386] Anionic surfactants Suitable anionic surfactants for detergents and cleaning compositions according to the present invention may include any conventional anionic surfactant. Typical examples of anionic surfactants include: C10-C18 alkylbenzene sulfonates; C10-C18 alkyl sulfates; C10-C18 alkyl sulfates ethoxylated with 1-3 moles of ethylene oxide; C10-C18 alpha-olefin sulfonates; C8-C18 alkyl carboxylates ethoxylated with 1-10 moles of ethylene oxide; and any mixture thereof.

[0387] In preferred variations of the detergent and cleaning composition according to the present invention, the anionic surfactant is, C10-C13 alkylbenzene sulfonates; C12-C15 alkyl sulfates; • C12-C14 alkyl sulfates ethoxylated with 1-3 moles of ethylene oxide; C12-C16 alpha-olefin sulfonates; C8-C18 alkyl carboxylates ethoxylated with 3-10 moles of ethylene oxide; Selected from the group consisting of and any mixture thereof.

[0388] In more preferred variations of the detergents and cleaning compositions according to the first and second embodiments of the present invention, the anionic surfactant is: Dodecylbenzenesulfonate; Dodecyl sulfate; • Dodecyl sulfate ethoxylated with 2 moles of ethylene oxide; C12-C14 alpha-olefin sulfonates; • C18 alkyl carboxylate ethoxylated with 9-10 moles of ethylene oxide; Selected from the group consisting of and any mixture thereof.

[0389] In the case of laundry detergents, the anionic surfactant is most preferably selected from the group consisting of dodecylbenzenesulfonate, dodecyl sulfate, dodecyl sulfate ethoxylated with 2 moles of ethylene oxide, and any mixture thereof.

[0390] For dishwashing detergents, the anionic surfactant is most preferably selected from the group consisting of dodecyl sulfate, dodecyl sulfate ethoxylated with 2 moles of ethylene oxide, and any mixture thereof.

[0391] For hard surface cleaning detergents, the anionic surfactant is most preferably selected from the group consisting of dodecyl sulfate, dodecyl sulfate ethoxylated with 2 moles of ethylene oxide, and any mixture thereof.

[0392] Cationic surfactants Suitable cationic surfactants for detergents and cleaning compositions according to the present invention may include any conventional cationic surfactant. Typical examples of cationic surfactants include: • Quaternary C8-C18 alkylethanolamines; • Quaternary C8-C18 alkylammonium compounds; C8-C18 alkylammonium methosulfate; and any mixture thereof.

[0393] In preferred variations of the detergent and cleaning composition according to the present invention, the cationic surfactant is • Quaternary C12-C18 alkylethanolamines; • Quaternary C12-C18 alkylammonium compounds; C12-C18 alkylammonium methosulfate; Selected from the group consisting of and any mixture thereof.

[0394] In more preferred variations of the detergents and cleaning compositions according to the first and second embodiments of the present invention, the cationic surfactant is • Quaternary C16-C18 alkylethanolamines; • Quaternary C16-C18 alkylammonium compounds; C14-C18 alkylammonium methosulfate; Selected from the group consisting of and any mixture thereof.

[0395] In the case of hard surface cleaning detergents, the cationic surfactant is most preferably selected from the group consisting of quaternary C16-C18 alkylammonium compounds and any mixture thereof.

[0396] In the case of fabric softeners, the cationic surfactant is most preferably selected from the group consisting of C14-C18 alkylammonium methosulfates and any mixture thereof.

[0397] Nonionic surfactants Suitable nonionic surfactants for detergents and cleaning compositions according to the present invention may include any conventional nonionic surfactant. Typical examples of nonionic surfactants include: C6-C18 fatty alcohols ethoxylated with 1-12 moles of ethylene oxide; • Alkoxylated C6-C18 fatty alcohols, for example C6-C18 fatty alcohols ethoxylated with 1-25 moles of ethylene oxide, C6-C18 fatty alcohols propoxylated with 1-15 moles of propylene oxide, C6-C18 fatty alcohols butoxylated with 1-10 moles of butylene oxide, and their combinations; • C6-C18 sophorolipids; • C6-C18 rhamnolipids; C5-C18 alkyl polyglycosides; C6-C18 alkanolamides; • C6-C18 fatty acid ester alkoxylates; and any mixture thereof.

[0398] In preferred variations of the detergent and cleaning composition according to the present invention, the nonionic surfactant is: C8-C15 fatty alcohols ethoxylated with 3-8 moles of ethylene oxide; • Alkoxylated C8-C15 fatty alcohols, for example C8-C15 fatty alcohols ethoxylated with 1-25 moles of ethylene oxide, C8-C15 fatty alcohols propoxylated with 1-15 moles of propylene oxide, C8-C15 fatty alcohols butoxylated with 1-10 moles of butylene oxide, and their combinations; • C8-C18 sophorolipids; • C8-C18 rhamnolipids; C7-C15 alkyl polyglycosides; C8-C15 alkanolamides; • C8-C15 fatty acid ester alkoxylates; Selected from the group consisting of and any mixture thereof.

[0399] In a more preferred variation of the detergent and cleaning composition according to the present invention, the nonionic surfactant is: • C10-C18 sophorolipids; • C10-C18 rhamnolipids; C8-C14 alkyl polyglycosides; Cocamide DEA / MEA; • C10-C14 fatty acid ester alkoxylates; Selected from the group consisting of and any mixture thereof.

[0400] In a more preferred variation of the detergent and cleaning composition according to the present invention, the nonionic surfactant is: • C10-C18 sophorolipids; • C10-C18 rhamnolipids; C8-C14 alkyl polyglycosides; Selected from the group consisting of and any mixture thereof.

[0401] The aforementioned nonionic detergents are particularly useful for preparing "green" detergents and cleaning compositions.

[0402] In the case of laundry detergents, dishwashing detergents, and hard surface cleaning detergents, the nonionic surfactant is most preferably selected from the group consisting of C10-C18 sophorolipids, C10-C18 rhamnolipids, C8-C14 alkyl polyglycosides, and any mixture thereof.

[0403] In a more preferred variation, for laundry detergents, the nonionic surfactant is selected from the group consisting of C12-C14 fatty alcohols ethoxylated with 7 moles of ethylene oxide, C13-C15 fatty alcohols ethoxylated with 7 moles of ethylene oxide, and any mixture thereof.

[0404] In a more preferred modification, for hard surface cleaning such as degreasing agents, the nonionic surfactant is selected from the group consisting of C9-C11 fatty alcohols ethoxylated with 3-8 moles of ethylene oxide, C10 fatty alcohols ethoxylated with 3-8 moles of ethylene oxide, and any mixture thereof.

[0405] In a more preferred variation, for automatic dishwashing, the nonionic surfactant is selected from the group consisting of C12-C14 fatty alcohols ethoxylated with 5 moles of ethylene oxide and / or propoxylated with 4 moles of propylene oxide.

[0406] Amphoteric / zwitterionic surfactants Suitable amphoteric / zwitterionic surfactants for detergents and cleaning compositions according to the present invention may include any conventional amphoteric / zwitterionic surfactant. Typical examples of amphoteric / zwitterionic surfactants include: C10-C18 N-(alkyl)-N,N-dimethylamine oxide; C10-C18 N-(alkyl)-N,N-bis(2-hydroxyethyl)amine oxide; C10-C18 alkylamidopropyl dimethylamine oxide; C10-C18 alkylbetaines; C10-C18 alkylamidobetaine; C10-C18 sulfobetaine; and any mixture of the above surfactants.

[0407] In preferred variations of the detergent and cleaning composition according to the present invention, the amphoteric / zwitterionic surfactant is C10-C15 N-(alkyl)-N,N-dimethylamine oxide; C10-C15 N-(alkyl)-N,N-bis(2-hydroxyethyl)amine oxide; C10-C15 alkylamidopropyl dimethylamine oxide; C10-C15 alkyl betaines; C10-C15 alkylamidobetaine; C10-C15 sulfobetaine; The group consists of the above surfactants and any mixture thereof.

[0408] In a more preferred variation of the detergent and cleaning composition according to the present invention, the amphoteric / zwitterionic surfactant is, C12-C14 N-(alkyl)-N,N-dimethylamine oxide; C12-C14 N-(alkyl)-N,N-bis(2-hydroxyethyl)amine oxide; C12-C14 alkylamidopropyl dimethylamine oxide; C12-C14 alkyl betaines; C12-C14 alkylamidobetaine; C12-C14 sulfobetaine; The group consists of the above surfactants and any mixture thereof.

[0409] For dishwashing detergents, the amphoteric / zwitterionic surfactant is most preferably selected from the group consisting of C12-C14 alkyl betaines and any mixture thereof.

[0410] In a preferred modification, the detergent and cleaning composition according to the present invention are C10-C18 alkylbenzene sulfonates; C10-C18 alkyl sulfates; C10-C18 alkyl sulfates ethoxylated with 1-3 moles of ethylene oxide; C10-C18 alpha-olefin sulfonates; • C8-C18 alkyl carboxylates ethoxylated with 1-10 moles of ethylene oxide; and • The mixture comprises an anionic surfactant selected from the group consisting of preferred variations thereof identified earlier, or a mixture of two or more anionic surfactants.

[0411] In a more preferred variation, the detergent and cleaning composition according to the present invention are • Quaternary C8-C18 alkylethanolamines; • Quaternary C8-C18 alkylammonium compounds; ·C8-C18 alkylammonium methosulfate; and • A cationic surfactant selected from the group consisting of preferred variations thereof identified above, or a mixture of two or more cationic surfactants.

[0412] In a more preferred variation, the detergent and cleaning composition according to the present invention are C8-C15 fatty alcohols ethoxylated with 3-8 moles of ethylene oxide; • Alkoxylated C8-C15 fatty alcohols, for example C8-C15 fatty alcohols ethoxylated with 1-25 moles of ethylene oxide, C8-C15 fatty alcohols propoxylated with 1-15 moles of propylene oxide, C8-C15 fatty alcohols butoxylated with 1-10 moles of butylene oxide, and their combinations; • C8-C18 sophorolipids; • C8-C18 rhamnolipids; C7-C15 alkyl polyglycosides; C8-C15 alkanolamides; • C8-C15 fatty acid ester alkoxylates; and • A nonionic surfactant selected from the group consisting of preferred variations thereof identified above, or a mixture of two or more nonionic surfactants.

[0413] The specific surfactants described above may be used either as a single surfactant from the same surfactant category (anionic, cationic, nonionic, or amphoteric / zwitterionic), or as a mixture of two, three, or more surfactants, or as a mixture of surfactants from different surfactant categories.

[0414] In the most preferred variation, the detergents and cleaning compositions according to the present invention include a combination mixture of one or more anionic surfactants and one or more nonionic surfactants as specified herein, i.e., a combination of one or more anionic surfactants and one or more nonionic surfactants.

[0415] Alternatively, the detergents and cleaning compositions according to the present invention include a combination mixture of one or more cationic surfactants and one or more nonionic surfactants as specified herein, i.e., a combination of one or more cationic surfactants and one or more nonionic surfactants.

[0416] The above numerical ranges, given in the form "Cx~Cy" and enumerated with respect to the number of carbon atoms in a surfactant, include the value defining the range and each integer within the defined range, such that the range C10~C18 includes C10, C11, C12, C13, C14, C15, C16, C17, and C18. For example, the term "C10~C18 alkyl" includes decyl, undecyl, dodecyl, tridecyl, tetradecyl, pentadecyl, hexadecyl, heptadecyl, and octadecyl. Similarly, the term "C12~C14 alkyl" includes dodecyl, tridecyl, and tetradecyl. For example, the term "C6~C18 fatty alcohol" includes fatty alcohols having carbon chains with 6, 7, 8, 9, 10, 11, 12, 13, 14, 15, 16, 17, or 18 carbon atoms. Similarly, the term "C6-C18 rhamnolipid" includes structures that contain rhamnolipids and carbon chains having 6, 7, 8, 9, 10, 11, 12, 13, 14, 15, 16, 17, or 18 carbon atoms.

[0417] Further enzyme stabilizers / components (d1, d2, d3, d) Enzyme detergents and cleaning compositions according to the first and second aspects of the present invention optionally include at least one additional enzyme stabilizer (d1, d2, d3, d) different from the enzyme stabilizers (b1, b2, b3, b) to further stabilize the enzymes in the detergents and cleaning compositions from loss of performance (i.e., to maintain proteolytic activity or enzyme retention). The enzymes are stabilized by the additional enzyme stabilizers via physical protection by a protective layer.

[0418] Negatively charged anionic surfactants capture Ca ions and / or Mg ions from the cleaning solution, forming complexes. This complex formation leads to a decrease in cleaning performance. To prevent this complex formation, chelating agents such as EDTA and HEDP are added to detergents and cleaning compositions. However, these chelating agents not only complexe Ca ions and / or Mg ions from the cleaning solution but also capture Ca ions and Mg ions from the surface of enzymes, which then leads to denaturation. Consequently, the enzymes lose their active form, which then leads to a decrease in enzyme activity. Therefore, enzyme stabilizers are added to detergents and cleaning compositions to protect the enzymes. Thus, chelating agents can capture only Ca ions and / or Mg ions from the cleaning solution but can no longer capture Ca ions and / or Mg ions from the surface of enzymes. Therefore, enzyme activity can be maintained by adding enzyme stabilizers.

[0419] The formulation of detergents and cleaning compositions may vary depending on the specific enzyme used.

[0420] The enzymes used herein are stabilized by the presence of a water-soluble source of calcium and / or magnesium ions in the final detergent and cleaning composition, which provides such ions to the enzyme. Calcium ions are generally somewhat more effective than magnesium ions and are preferred herein when only one type of cation is used. Typical detergent and cleaning compositions, especially liquids, contain 1 to 30 mmol, preferably 2 to 20 mmol, more preferably 5 to 15 mmol, and most preferably 8 to 12 mmol of calcium ions per liter of the final composition.

[0421] It should be understood that the aforementioned levels of calcium and / or magnesium ions are sufficient to provide enzyme stability. More calcium and / or magnesium ions may be added to the composition to provide an additional measure of grease removal performance. Therefore, as a general suggestion, the compositions herein typically contain 0.01% to 2% by weight of a water-soluble source of calcium or magnesium ions, or both. This amount may, of course, vary depending on the amount and type of enzyme used in the composition.

[0422] Additional enzyme stability may be provided by the presence of various other stabilizers disclosed in the art, particularly borate species, with reference to U.S. Patent No. 4,537,706, which is incorporated herein by reference in whole.

[0423] One group of stabilizers is reversible protease inhibitors. Benzamidine hydrochloride, borax, boric acid, boronic acid, or salts or esters thereof, including derivatives having aromatic groups, are frequently used for this purpose. Typically, such enzyme stabilizers are used in a composition at a level of 0.05% to 5% by weight, more preferably 0.075% to 3% by weight, of boric acid or other borate compounds capable of forming boric acid in the composition (calculated based on boric acid). While boric acid is preferred, other compounds such as boron oxide, borax, and other alkali metal borates (e.g., sodium orthoborate, sodium metaborate, and sodium pyroborate, and sodium pentaborate) are also suitable. Substituted boric acids (e.g., phenylboronic acid, butaneboronic acid, and p-bromophenylboronic acid) can also be used instead of boric acid.

[0424] Furthermore, peptaldehydes, i.e., oligopeptides with a reduced C-terminus, particularly those with 2 to 50 monomers, or their bisulfite adducts, can be used for this purpose. Examples of peptidically reversible protease inhibitors include, but are not limited to, ovomucoids and leupeptins. Specific reversible peptide inhibitors for the protease subtilisin, as well as fusion proteins from proteases and specific peptide inhibitors, are also suitable for this purpose.

[0425] Further enzyme stabilizers include amino alcohols, such as mono-, di-, triethanolamine, and propanolamine, and mixtures thereof; aliphatic carboxylic acids up to C12, such as succinic acid, other dicarboxylic acids, or salts of the above acids.

[0426] End-capped fatty acid amide alkoxylates are also suitable for this purpose.

[0427] Preferably, the further enzyme stabilizers (d1, d2, d3, d) in the detergents and cleaning compositions according to the present invention are selected from the group consisting of polyols, e.g., glycols, e.g., monopropylene glycol, glycerin, mannitol, isomaltol, sorbitol, xylitol, treitol, erythritol, arabitol; amino alcohols, e.g., mono-, di-, triethanolamine and -propanolamine; aliphatic carboxylic acids up to C12, e.g., succinic acid and its salts; dicarboxylic acids and their salts; terminally capped fatty acid amide alkoxylates; salts, preferably calcium and magnesium salts, e.g., calcium chloride, calcium formate, magnesium chloride, magnesium formate; reversible enzyme inhibitors, e.g., borate-containing compositions, e.g., 4-FBPA; boron-free inhibitors, e.g., disubstituted alaninamide, sodium formate; and any mixture thereof.

[0428] Most preferably, the further enzyme stabilizers (d1, d2, d3, d) in the detergent and cleaning composition according to the present invention are selected from the group consisting of calcium chloride, calcium formate, magnesium chloride, magnesium formate, and any mixture thereof.

[0429] Furthermore, the addition of the aforementioned enzyme stabilizers can prevent negatively charged anionic surfactants from forming complexes with Ca ions and / or Mg ions from the cleaning solution, thereby reducing or losing their cleaning performance.

[0430] Preferably, at least one enzyme (a1, a2, a3, a) is added to the detergent and cleaning compositions according to the first and second embodiments of the present invention as an enzyme preparation mixed with at least one further enzyme stabilizer (d1, d2, d3, d) identified above, and optionally a buffer.

[0431] In a more preferred variation, at least one enzyme (a1, a2, a3, a) is added to the detergent and cleaning composition according to the present invention as an enzyme preparation mixed with one or more further enzyme stabilizers (d1, d2, d3, d) and a specific type of enzyme stabilizer (b1, b2, b3, b), for example, an alkanediol, glyceryl caprylate, 4-hydroxyacetophenone, ethylhexylglycerin, tropolone, or a mixture of the aforementioned enzyme stabilizers different from the further enzyme stabilizers as defined herein, and optionally a buffer.

[0432] Surprisingly, the addition of enzyme stabilizers (b1, b2, b3, b) as defined herein was found to enhance or boost the enzyme-stabilizing effect of further enzyme stabilizers (d1, d2, d3, d3).

[0433] Unexpectedly, the combination of enzyme stabilizers (b1, b2, b3, b) and additional enzyme stabilizers (d1, d2, d3, d) results in a synergistic enzyme stabilization effect in enzyme-containing detergents and cleaning compositions compared to the use of enzyme stabilizers (b1, b2, b3, b) alone or the use of a single additional enzyme stabilizer (d1, d2, d3, d) alone.

[0434] We were able to observe specific enhancing effects when enzyme stabilizers (b1, b2, b3, b), such as alkanediols having carbon chains of 5 to 14 carbon atoms, glyceryl caprylate, 4-hydroxyacetophenone, ethylhexylglycerin, tropolone, or mixtures of the aforementioned enzyme stabilizers, were used in combination with enzyme stabilizers (d1, d2, d3, d), which include calcium chloride, calcium formate, magnesium chloride, magnesium formate, and any mixtures thereof.

[0435] With respect to detergents, cleaning compositions, and enzyme preparations according to the present invention, the list of enzyme stabilizers (b1, b2, b3, b) specified herein may be optionally combined with the list of further enzyme stabilizers (d1, d2, d3, d) specified herein.

[0436] When one or more of the following enzyme stabilizers (b1, b2, b3, b) are used in combination with one or more further enzyme stabilizers (d1, d2, d3, d) as defined herein, preferably calcium chloride, calcium formate, magnesium chloride, magnesium formate, and any mixture thereof, a significant synergistic enzyme stabilization effect is observed: • 1,2-pentanediol; • 1,2-Hexanediol; • 1,2-heptanediol; • 1,2-octanediol; • 1,2-nonanediol; • 1,2-decanediol; • 1,2-Undecanediol; • 1,2-dodecanediol; • 1,2-Tridecanediol; • 1,2-tetradecanediol; Glyceryl caprylate; ·4-hydroxyacetophenone; Ethylhexylglycerin; • Tropolone; • A mixture containing 1,2-hexanediol and 1,2-octanediol; • A mixture containing 1,2-hexanediol, 1,2-octanediol, and tropolone; and A mixture containing 4-hydroxyacetophenone and 1,2-octanediol.

[0437] Therefore, the combined addition of the enzyme stabilizer defined herein with further enzyme stabilizers results in improved enzyme stability compared to the enzyme stabilization effect of the single agent. Detergents and cleaning compositions containing the aforementioned mixtures exhibit improved cleaning properties compared to detergents and cleaning compositions without such mixtures.

[0438] Any further ingredients Within the context of the present invention, it is possible, and in some cases advantageous, to obtain ready-to-use compositions or formulations by combining detergents and cleaning compositions according to the first or second aspects of the present invention with other active substances and / or additives, depending on the purpose of the composition. The active ingredients provide the detergents and cleaning compositions according to the present invention with desired properties and functionality. The terms “functional ingredient” or “functional additive” include ingredients that provide beneficial properties in a particular use. Some specific examples of functional ingredients are described in more detail below. However, a wide variety of other functional ingredients can also be used.

[0439] The detergents and cleaning compositions according to the present invention may contain any of the components commonly found in such compositions, such as organic solvents, builders, and further auxiliary agents, such as antifouling agents, thickeners, colorants, and fragrances.

[0440] Preferably, the detergents and cleaning compositions according to the present invention may be advantageously combined with or modified by at least one active substance and / or at least one (functional) additive, such as solvents, builders, bleaches, stain removers, dispersants, anti-foaming agents, metal ion sequestering agents, chelating agents, anti-redeposition agents, anti-color transfer / color protection agents, dye scavengers, dyes, anti-graying agents, fluorescent whitening agents, ultraviolet light absorbers, thickeners or rheological modifiers, hydrotropes, solubility modifiers, pH adjusters, buffers, solvents, antistatic agents, anti-wrinkle agents, antimicrobial agents, odor removers / odor scavengers, ultraviolet light protection agents, fragrances, bactericides, disinfectants, water repellents, insect repellents, anti-pilling agents, scouring agents, antifungal agents, anti-allergic agents, and any mixtures thereof.

[0441] Chelating agents / metal ion sequestering agents The detergents and cleaning compositions disclosed herein may optionally contain one or more chelating agents capable of complexing iron, manganese, and / or calcium ions. This also allows for water softening. In addition, negatively charged anionic surfactants capture Ca ions and / or Mg ions from the cleaning solution, forming complexes. This complex formation leads to a decrease in cleaning performance. To prevent this complex formation, chelating agents, such as those described below, are also added to the detergents and cleaning compositions. Thus, the addition of chelating agents ensures that the performance of the anionic surfactants in the detergents and cleaning compositions is not reduced.

[0442] Chelating agents may exist in the form of acids or salts, including alkali metals, ammonium, and their substituted ammonium salts, as well as mixtures thereof.

[0443] Preferably, the chelating agent is selected from the group consisting of aminocarboxylates, phosphonates, or mixtures thereof.

[0444] The agents used herein include chemicals that interact with divalent ions, cations, and anions and tend to precipitate in saturated aqueous solutions thereof.

[0445] Useful aminocarboxylate chelating agents include, but are not limited to, the following: N-(1,2-dicarboxy-ethyl)-D,L-aspartic acid (IDS), N-(2-hydroxyethyl)iminodiacetic acid (EDG), aspartic acid-N-monoacetic acid (ASMA), aspartic acid-N,N-diacetic acid (ASDA), aspartic acid-N-monopropionic acid (ASMP), iminodisuccinic acid (IDA), N-(2-sulfomethyl)aspartic acid (SMAS), N-(2-sulfoethyl)aspartic acid (SEAS), N-(2-sulfomethyl)glutamic acid (SMGL), N-(2-sulfoethyl) Chil(glutamic acid) (SEGL), N-methyliminodiacetic acid (MIDA), α-alanine-N,N-diacetic acid (α-ALDA), serine-N,N-diacetic acid (SEDA), isoserine-N,N-diacetic acid (ISDA), phenylalanine-N,N-diacetic acid (PHDA), anthranilic acid-N,N-diacetic acid (ANDA), sulfanilic acid-N,N-diacetic acid (SLDA), taurine-N,N-diacetic acid (TUDA), sulfomethyl-N,N-diacetic acid (SMDA), N-(hydroxyethyl)-ethylidenediamine triacetate (HEDTA), diethanolglycine (DEG), aminotris(methylenephosphonic acid) (ATMP).

[0446] Preferred chelating agents may contain amino groups, for example, amino-polycarboxylates or phosphonates. They may be monomer molecules containing one, two, or three amino groups (typically secondary or tertiary amino groups), and they may contain two, three, four, or five carboxyl groups or even more. The chelating agent may or may not contain phosphorus. Suitable chelating agents include those based on carboxylate groups, such as EDTA (ethylenediaminetetraacetic acid), NTA (2,2',2''-nitrilotriacetic acid), citrate, 2-hydroxypropane 1,2,3-tricarboxylate, DTPA (diethylenetriaminepentaacetic acid), MGDA (methylglycine diacetic acid OT N,N'-bis(carboxymethyl)alanine), EGTA (ethylene glycol tetraacetic acid), EDDS (ethylenediamine N,W-nicuccinic acid), and GLDA (L-glutamic acid, N,N-diacetic acid). The composition may also preferably include other polycarboxylates such as PAA [poly(acrylic acid)], PAA / PMA [copoly(acrylic acid / maleic acid)], or mixtures thereof.

[0447] Another group of preferred chelating agents includes phosphonates. Aminoalkanes and / or hydroxyalkane phosphonates are preferably used as phosphonates. Suitable examples of these phosphonate chelating agents include HEDP (l-hydroxyethylidene 1,1-diphosphonic acid), EDTMP [ethylenediaminetetra(methylenephosphonic acid)], EDTMPA (ethylenediaminetetramethylene-tetraphosphonic acid), DTPMP (diethylenetriaminepenta(methylenephosphonic acid), DTMPA (diethylenetriaminepenta(methylenephosphonic acid))nitrilotris(methylenephosphonic acid)) (NTMP), 2-phosphonobutane-1,2,4-tricarboxylic acid (PBTC), ethylenediaminetetramethylenephosphonate (EDTMP), Examples include these and their higher homologues. Among hydroxyalkanephosphonates, 1-hydroxyethane-1,1-diphosphonate (HEDP) is particularly important. The chelating agents may be contained in nitrogen, for example, EDTA, NTA, DTPA, PDTA, GLDA, MGDA, EDDS, EDTMP, EDTMPA, and DTPMP, or in ASMA, ASDA, ASMP, IDA, SMAS, SEAS, SMGL, SEGL, MIDA, α-ALDA, SEDA, ISDA, PHDA, ANDA, SLDA, TUDA, SMDA, HEDTA, DEG, ATMP, or mixtures thereof.

[0448] Particularly preferred chelating agents include, but are not limited to, ethylenediaminetetraacetic acid (EDTA), diethylenetriaminepentamethylenephosphonic acid (DTMPA, DTPMP), hydroxyethanediphosphonic acid (HEDP), ethylenediamine N,N-nicuccinic acid (EDDS), methylglycinediacetic acid (MGDA), diethylenetriaminepentaacetic acid (DTPA), propylenediaminetetraacetic acid (PDTA), 2-hydroxypyridine-N-oxide (HPNO), methylglycinediacetic acid (MGDA), glutamic acid N,N-diacetic acid (N,N-dicarboxymethylglutamate tetrasodium salt (GLDA)), nitrilotriacetic acid (NTA), sodium citrate, or mixtures thereof. The chelating agents may exist in their acidic form or as salts, and preferably, the chelating agents may exist as sodium salts, ammonium salts, or potassium salts.

[0449] Particularly preferred chelating agents include diethylenetriaminepentaacetic acid (DTPA), ethylenediamine-N,N'-disuccinic acid (EDDS), and 1,1-hydroxyethanediphosphonic acid (HEDP) or their alkali metal salts, potassium salts, alkaline earth metal salts, ammonium salts, or substituted ammonium salts, or mixtures thereof. The most preferred chelating agent is phosphonate. Examples of phosphonate chelating agents include HEDP in its acidic form or in salt form with alkali metals, potassium, alkaline earth metals, ammonium, or substituted ammonium.

[0450] The most preferred chelation methods are: GLDA, MGDA, sodium citrate, HEDP, and any mixture thereof.

[0451] In the detergent and cleaning composition according to the present invention, the chelating agent is typically present in an amount of 0.1 to 10.0% by weight, preferably 0.1 to 5.0% by weight, and more preferably 0.1 to 3.0% by weight, based on the total weight of the composition.

[0452] Preferably, the detergents and cleaning compositions according to the present invention contain at least 0.2% by weight, more preferably at least 0.3% by weight, even more preferably at least 0.5% by weight, and most preferably at least 0.6% by weight of a chelating agent based on the total weight of the composition, but typically contain 3% by weight or less, more preferably 2% by weight or less, and most preferably 1% by weight or less of a chelating agent.

[0453] However, in some automatic dishwashing gels, the amount of GLDA can be 30-40% by weight based on the total weight of the composition.

[0454] Antimicrobial agents The detergent and cleaning composition may further contain one or more antimicrobial agents.

[0455] In the context of this invention, the term “antimicrobial component” refers to a group of substances, particularly agents that kill or stop or inhibit the growth of microorganisms such as bacteria, yeasts, and / or fungi, thereby preventing microbial contamination of a product. Without the addition of such agents, the product may spoil, exhibit changes in odor, discoloration, mold growth, gas formation, emulsion separation, or viscosity changes, making the product unacceptable to consumers.

[0456] Suitable antimicrobial agents include, but are not limited to, phenols, quaternary ammonium compounds, metal derivatives, amines, alkanolamines, nitro derivatives, analides, organosulfurs and sulfur-nitrogen compounds, and various other compounds. Exemplary phenolic agents include pentachlorophenol, orthophenylphenol, and phenoxyethanol. Exemplary quaternary antimicrobial agents include benzalkonium chloride, cetylpyridinium chloride, amine and nitro-containing antimicrobial compositions, such as hexahydro-1,3,5-tris(2-hydroxyethyl)-s-triazine, dithiocarbamates, such as sodium dimethyldithiocarbamate, and various other materials whose antimicrobial properties are known in the art. Other exemplary antimicrobial agents include glutaraldehyde, bronopol (2-bromo-2-nitropropane-1,3-diol), silver, and isothiazolone, such as methylisothiazolinone, ethyl HCl lauroyl alginate sold under the trade name Neolone®, sodium benzoate, benzyl alcohol, or methylbenzyl alcohol.

[0457] In preferred variations of the present invention, the detergent and cleaning composition are further combined with benzyl alcohol, methylbenzyl alcohol, phenoxyethanol, and any mixture thereof. The aforementioned substances have broad-spectrum activity against microorganisms and are added to the detergent composition to inhibit microbial decay and therefore for stabilization purposes.

[0458] In particular, antimicrobial agents are added to liquid detergents due to their higher water content, which makes such compositions susceptible to the invasion and growth of microorganisms.

[0459] If an antimicrobial agent is included in the detergent and cleaning composition of the present invention, it is preferably in an amount of about 0.0001% to about 15% by weight, particularly 0.001% to 10% by weight, and most particularly 0.001% to 5% by weight, based on the total weight of the composition.

[0460] Enzymes are typically incorporated into detergents and cleaning compositions according to this disclosure in an amount sufficient to provide effective cleaning during the cleaning procedure. An effective cleaning amount means an amount that provides a clean, hygienic, and preferably non-corrosive appearance to the cleaned material, particularly medical or dental devices or instruments. An effective cleaning amount may also mean an amount that produces a cleaning effect, stain removal effect, dirt removal effect, whitening effect, deodorizing effect, or freshness-improving effect on a substrate, such as medical or dental devices or instruments. Such cleaning effects can be achieved with a small amount of enzyme, approximately 0.02% by weight of the detergent or cleaning composition.

[0461] In the detergents and cleaning compositions of this disclosure, adequate cleaning can typically be achieved when the enzyme is present in an amount of about 0.0001 to about 35% by weight, preferably about 2 to about 15% by weight, preferably about 3 to about 10% by weight, preferably about 4 to about 8% by weight, preferably about 4, about 5, about 6, about 7, or about 8% by weight. Higher enzyme levels are typically desirable in highly concentrated cleaning formulations.

[0462] In the detergent and cleaning composition of the present invention, adequate cleaning can be achieved when the enzyme is present in an amount of 0.0001 to 5% by weight based on the total weight of the composition. Preferably, the enzyme is present in an amount of 0.0001 to 4% by weight based on the total weight of the composition. More preferably, the detergent and cleaning composition according to the present invention contains the enzyme in an amount of 0.001 to 3% by weight based on the total weight of the composition. Most preferably, the enzyme is present in the detergent and cleaning composition in an amount of 0.01 to 2% by weight based on the total weight of the composition. Even more preferably, the enzyme is present in the detergent and cleaning composition in an amount of 0.05 to 2% by weight based on the total weight of the composition.

[0463] Typically, enzymes are present in the detergent and cleaning compositions according to the present invention in an amount of 0.05 to 2.0% by weight. Usually, proteases and amylases are used in higher concentrations in the detergent and cleaning compositions, i.e., based on the total weight of the composition, proteases in an amount of 0.4 to 1.5% by weight and amylases in an amount of 0.05 to 0.6% by weight.

[0464] In the case of enzyme cocktails, the above amounts refer to the total amount of enzymes in the mixture; that is, the amount is the sum of the amounts of all enzymes in the mixture.

[0465] A mixture containing 1,2-heptanediol (b1) or 2,3-heptanediol (b2) or 1,2-heptanediol and 2,3-heptanediol (b3) according to a first aspect of the present invention is present in the detergent and cleaning composition in an amount of 0.001 to 15.0% by weight based on the total weight of the composition. In a preferred variation, the detergent and cleaning composition contains a mixture containing 1,2-heptanediol (b1) or 2,3-heptanediol (b2) or 1,2-heptanediol and 2,3-heptanediol (b3) in an amount of 0.01 to 10.0% by weight based on the total weight of the composition. In a more preferred variation, a mixture containing 1,2-heptanediol (b1) or 2,3-heptanediol (b2), or 1,2-heptanediol and 2,3-heptanediol (b3), is advantageously used in detergents and cleaning compositions in an amount of 0.1 to 5.0% by weight based on the total weight of the composition. In an even more preferred variation, a mixture containing 1,2-heptanediol (b1) or 2,3-heptanediol (b2), or 1,2-heptanediol and 2,3-heptanediol (b3), is advantageously used in detergents and cleaning compositions in an amount of 0.3 to 3.0% by weight based on the total weight of the composition. In the most preferred variation, a mixture containing 1,2-heptanediol (b1) or 2,3-heptanediol (b2) or 1,2-heptanediol and 2,3-heptanediol (b3) is advantageously used in detergent and cleaning compositions in an amount of 0.5 to 1.0% by weight based on the total weight of the composition.

[0466] With respect to the heptanediol mixture (b3), the above amount refers to the total content of 1,2-heptanediol and 2,3-heptanediol in the mixture; that is, this amount is the sum of the content of 1,2-heptanediol and 2,3-heptanediol in the mixture.

[0467] The at least one enzyme stabilizer (b) according to the present invention is present in the detergent and cleaning composition in an amount of 0.001 to 15.0% by weight based on the total weight of the composition. In a preferred variation, the detergent and cleaning composition contains at least one enzyme stabilizer (b) in an amount of 0.01 to 10.0% by weight based on the total weight of the composition. In a more preferred variation, at least one enzyme stabilizer (b) is favorably used in the detergent and cleaning composition in an amount of 0.1 to 5.0% by weight based on the total weight of the composition. In an even more preferred variation, at least one enzyme stabilizer (b) is favorably used in the detergent and cleaning composition in an amount of 0.3 to 3.0% by weight based on the total weight of the composition. In the most preferred variation, at least one enzyme stabilizer (b) is favorably used in the detergent and cleaning composition in an amount of 0.5 to 1.0% by weight based on the total weight of the composition.

[0468] For an alkanediol mixture containing at least one first linear alkanediol and one or more second linear alkanediols, the above amount is with respect to the total content of the first linear alkanediol and the second linear alkanediol in the mixture; that is, this amount is the sum of the content of the first linear alkanediol and the second linear alkanediol in the mixture.

[0469] With respect to an enzyme stabilizer mixture containing two or more enzyme stabilizers, the above amount refers to the total content of enzyme stabilizers in the mixture, i.e., the amount is the sum of the content of each individual enzyme stabilizer in the mixture.

[0470] In a particularly preferred variation according to the first aspect of the present invention, the detergent and cleaning composition contain, based on the total weight of the composition, 2,3-heptanediol (b3) of 2,3-heptanediol or a mixture containing 1,2-heptanediol and 2,3-heptanediol in an amount of 0.001 to 15.0% by weight, preferably 0.01 to 10.0% by weight, more preferably 0.1 to 5.0% by weight, even more preferably 0.3 to 3.0% by weight, and most preferably 0.5 to 1.0% by weight.

[0471] More preferably, the detergent and cleaning composition contains 2,3-heptanediol or 2,3-heptanediol (b3) of a mixture containing 1,2-heptanediol and 2,3-heptanediol in an amount of 0.001 to 0.5% by weight, preferably 0.005 to 0.1% by weight, and most preferably 0.01 to 0.075% by weight, based on the total weight of the composition or home care product.

[0472] In a particularly preferred variation of the present invention, the detergent and cleaning composition contains, based on the total weight of the composition or home care product, a 2,3-alkanediol as a linear alkanediol, or a mixture containing at least one first linear alkanediol and one or more second linear alkanediols, in an amount of 0.001 to 15.0% by weight, preferably 0.01 to 10.0% by weight, more preferably 0.1 to 5.0% by weight, even more preferably 0.3 to 3.0% by weight, and most preferably 0.5 to 1.0% by weight.

[0473] More preferably, the detergent and cleaning composition contains, based on the total weight of the composition or home care product, 2,3-alkanediol as a linear alkanediol, or a mixture containing at least one first linear alkanediol and one or more second linear alkanediols, in an amount of 0.001 to 0.5% by weight, preferably 0.005 to 0.1% by weight, and most preferably 0.01 to 0.075% by weight.

[0474] Typically, at least one surfactant is present in the detergent and cleaning composition according to the present invention in an amount of more than 3% by weight based on the total weight of the composition. Preferably, the surfactant is present in an amount of 4 to 90% by weight based on the total weight of the composition. More preferably, the detergent and cleaning composition according to the present invention contains a surfactant in an amount of 10 to 60% by weight, more preferably 20 to 50% by weight, and most preferably 30 to 40% by weight, based on the total weight of the composition.

[0475] In contrast, the light-duty compositions according to the first and second embodiments of the present invention contain at least one surfactant in an amount of more than 3% to 40% by weight based on the total weight of the composition. Preferably, the surfactant is present in an amount of 4 to 30% by weight based on the total weight of the composition. The dishwashing and / or rinsing compositions according to the present invention contain the surfactant in an amount of 5 to 20% by weight, preferably 6 to 15% by weight, based on the total weight of the composition.

[0476] At least one additional enzyme stabilizer is present in the detergent and cleaning compositions according to the first and second embodiments of the present invention in an amount of 0.0001 to 5% by weight based on the total weight of the composition. Preferably, the additional enzyme stabilizer is present in an amount of 0.001 to 4% by weight based on the total weight of the composition. Most preferably, the detergent and cleaning compositions according to the first and second embodiments of the present invention contain an additional enzyme stabilizer in an amount of 0.01 to 3% by weight based on the total weight of the composition.

[0477] The detergents and cleaning compositions according to the present invention have been found to possess remarkably excellent enzyme stability. The more stable the enzymes in the composition, the longer they remain effective in removing dirt and stains. As a result, the detergents and cleaning compositions according to the present invention are enzymatically more effective over time compared to detergents and cleaning compositions without the enzyme stabilizers of the present invention.

[0478] In particular, when an effective amount of a specific type of enzyme stabilizer, as defined in detail herein, such as alkanediols, glyceryl caprylates, 4-hydroxyacetophenone, ethylhexylglycerin, tropolone, or a mixture of the aforementioned enzyme stabilizers, is added to detergents and cleaning compositions, remarkable enzyme stabilization properties are obtained, as demonstrated in the following examples, and the rate of enzyme inactivation in the detergents and cleaning compositions during storage is found to be significantly delayed. Such detergents and cleaning compositions exhibit improved cleaning properties compared to detergents and cleaning compositions without such enzyme stabilizers.

[0479] Unexpectedly, it has been observed that the enzymes in detergents and cleaning compositions can be stabilized by adding the enzyme stabilizers or enzyme stabilization cocktails identified above. While not bound by theory, it is assumed that the addition of the enzyme stabilizers identified herein will result in the formation of a protective layer, particularly preferably a coating, around the enzymes, to keep them stable or resistant to irritating components in the detergents and cleaning compositions, as assumed with known enzyme stabilizer glycols.

[0480] In particular, adding the enzyme stabilizers or enzyme stabilization cocktails specified above to detergents and cleaning compositions containing enzymes can maintain enzyme activity for extended periods during storage of the compositions. The enzyme stabilizers according to the present invention have a positive effect on enzyme performance by significantly slowing the rate of enzyme inactivation during storage. Therefore, the enzyme activity remains higher than that of detergents and cleaning compositions that do not contain such enzyme stabilizers of the present invention. The more stable the enzymes are, the more effective they are at removing dirt, proteins, starch, and fats. As a result, the detergents and cleaning compositions disclosed herein exhibit better cleaning performance after storage compared to detergents and cleaning compositions that do not contain enzyme stabilizers or enzyme stabilization cocktails.

[0481] In addition, the addition of such enzyme stabilizers as defined herein can even further improve the enzyme stabilizing effect of any additional enzyme stabilizers added to detergents and cleaning compositions.

[0482] Therefore, enzyme stabilization makes it possible to store detergents and cleaning compositions without or with at least a significant reduction in enzymatic degradation and deterioration. Surprisingly, when using the enzyme stabilizer according to the present invention, the shelf life of detergents and cleaning compositions can be extended with little or no enzymatic inactivation compared to compositions that do not contain the enzyme stabilizer of the present invention.

[0483] Beneficially, the enzyme detergents and cleaning compositions according to the present invention exhibit storage stability while maintaining enzyme activity, compared to detergents and cleaning compositions that do not contain the enzyme stabilizer of the present invention.

[0484] Furthermore, the enzyme detergents and cleaning compositions according to the present invention exhibit improved storage stability, allowing them to be stored at temperatures higher than standard room temperature (25°C), preferably at least 30°C, more preferably at least 35°C, for at least 2 weeks, more preferably at least 4 weeks, even more preferably at least 6 weeks, most preferably at least 8 weeks, and most preferably at least 12 weeks, while retaining enzyme efficacy and thus providing better cleaning performance.

[0485] Remarkably, the enzyme stabilizer according to the present invention provides enzyme stability to detergents and cleaning compositions over a wide pH range of pH 3 to pH 12. Therefore, the enzyme stabilizer of the present invention enables the stabilization of enzymes in a variety of detergents and cleaning compositions having different pH values ​​in the acidic, basic, or neutral pH range. This is particularly advantageous for detergents and cleaning compositions with acidic or basic pH values, such as bathroom cleaners or kitchen cleaners, where enzymes tend to be inactive or unstable.

[0486] If the enzyme stabilizers specified herein are not used, the enzyme stability in detergents and cleaning compositions containing the enzymes defined herein will decrease during storage, resulting in a decrease in the cleaning performance of the detergents and cleaning compositions at the time of use.

[0487] The enzyme stabilization effect is demonstrated by actual washing / cleaning tests in the following examples. As shown in this disclosure, the solutions prepared from the detergents and cleaning compositions according to the present invention maintain their activity for a much longer time compared to the detergents and cleaning compositions without the enzyme stabilizer of the present invention.

[0488] This enzyme stabilization effect results in a more effective composition due to its extended activity for removing dirt or stains.

[0489] Beneficially, the improved stability further allows for a reduction in the use of enzymes, enzyme stabilizers, or some other components commonly used in detergents and cleaning compositions. Due to the superior stability of the enzymes in the detergents and cleaning compositions of this disclosure, it is possible to use fewer enzymes in the composition without losing cleaning performance.

[0490] For superior enzyme stability in the detergents and cleaning compositions disclosed herein, the compositions may reduce or even omit other enzyme stabilizers, such as glycerol, or other components commonly used in existing detergents and cleaning compositions. Some stabilizers may be difficult to include in detergents and cleaning compositions or may cause undesirable reactions with other components. Some stabilizers may pose health / safety / labeling concerns in concentrated compositions (e.g., undesirable GHS labeling icon warnings). Using no other enzyme stabilizers at all, or only in small amounts, to manufacture the detergents and cleaning agents disclosed herein is a particular advantage.

[0491] Therefore, in a preferred modification, the detergents and cleaning compositions according to the present invention have fewer other components or further enzyme stabilizers different from the enzyme stabilizers specified above, such as a reduced amount of borate-containing components.

[0492] According to further aspects of the present invention, the detergents and cleaning compositions according to the first and second aspects of the present invention can be used on their own or for the preparation of detergents and cleaning products.

[0493] The enzyme detergents and cleaning compositions or products specified herein can be used in a variety of cleaning methods. As used herein, the term “cleaning” means performing, facilitating, or assisting in the removal of dirt, bleaching, reduction of microbial populations, disinfection, etc. Preferably, the enzyme detergents and cleaning compositions or products are useful for textile cleaning, laundry, dishwashing, fabric care, household, institutional and industrial hard surface cleaning, such as clothing or other surfaces, and cleaning medical and dental instruments.

[0494] Preferably, the enzymatic detergent and cleaning composition or product may be used to clean, wash, or pre-soak medical or dental devices, instruments, or apparatus, including any of the various medical or dental instruments or devices that can benefit from cleaning with the enzymatic cleaning composition. Exemplary medical and dental instruments and devices include instruments, devices, tools, appliances, apparatus, and equipment used in medical or dental settings, including those that can be sterilized at low temperatures, immersed or washed and then heat-sterilized. Medical and / or dental instruments may be contaminated with blood, mammalian tissue including but not limited to human tissue, or other foreign matter.

[0495] Suitable examples of detergents and cleaning compositions or products include heavy-duty detergents, color care detergents, light-duty detergents, general-purpose detergents, fabric softeners, fabric laundry fragrances, fragrance lotions, laundry wipes, dyes and / or stain removers (Press Potter, Vanish type), degreasing cleaners, washing machine cleaners, general-purpose cleaners, hand dishwashing detergents, automatic dishwashing detergents, hard surface cleaners, glass and mirror cleaners, wet cleaning wipes, kitchen cleaners, cookware cleaners, oven cleaners, floor cleaners, wood floor cleaners, carpet cleaners, bathroom and shower cleaners, toilet cleaners, grout cleaners, disinfectants, drain cleaners, toilet rim block gels, air fresheners, furniture polishes, car shampoos, and medical cleaning products.

[0496] The aforementioned detergents and cleaning compositions or products refer to compositions or products in liquid, solid, tablet, encapsulated, diluted or concentrated form, and optionally in two-compartment or multi-compartment form.

[0497] As used herein, liquids include free-flowing liquids, as well as pastes, gels, foams, and mousses. Non-limiting examples of liquids include light-duty and heavy-duty liquid detergents and cleaning compositions, fabric conditioners, detergent gels commonly used in laundry, bleaches, and laundry additives. Gases, such as suspended bubbles, or solids, such as particles, may be contained within the liquids.

[0498] Solids used herein include powders, flakes, granules, pellets, tablets, microcapsules, beads, noodles, pearlescent balls, lozenges, packs, briquettes, bricks, blocks, or other solid forms known to those skilled in the art.

[0499] Solid detergents and cleaning compositions or products may be provided as compressed solid blocks, cast solid blocks, extruded pellets or blocks, or tablets. Furthermore, solid detergent compositions or products may be provided in unit dose form. A unit dose refers to a solid detergent or cleaning composition unit of a size such that the entire unit is used in a single cleaning cycle.

[0500] Solid detergents and cleaning compositions or products may be provided in the form of multi-use (e.g., multi-use) solids such as blocks or multiple pellets, which can be repeatedly used to produce aqueous use solutions of the detergent composition for multiple cycles or a predetermined number of dispensing cycles. Multi-use solid detergent compositions can be repeatedly used to produce aqueous detergent compositions, e.g., use solutions, for multiple cleaning cycles. Compressed solid detergent blocks are made suitable to provide stability such that the reactive components in the composition do not react with each other until the time of dilution and / or use. In some embodiments, the order in which the components are introduced to form a solid is not limited, as the amount of water introduced into the solid composition is minimal and / or no water. However, in some embodiments, compressed solid detergent blocks are made by using a binding system to minimize any damage to the coated granules that can be used. Advantageously, the compression process for producing compressed solid detergent blocks produces compressed solid detergent blocks and prevents the reaction or mixing of the components. In one embodiment of the present disclosure, the solid detergent composition remains unreacted or unmixed until use, e.g., until dilution.

[0501] In a compression solid process, a fluid solid, such as a granular solid or other particulate solid containing a binder, is mixed under pressure. In a compression solid process, the fluid solid of the composition is placed into a mold (e.g., a mold or container). The method may include gently pressing the fluid solid in form to produce a solid cleaning composition.

[0502] Enzyme detergents and cleaning compositions or products may be supplied in concentrated form and diluted in a solution of use, or supplied as a solution of use. Preferably, the composition of use is diluted to a concentration of about 500 ppm to about 5000 ppm, more preferably about 750 ppm to about 4500 ppm, and most preferably about 1000 ppm to about 4000 ppm.

[0503] The enzyme detergents and cleaning compositions or products according to the present invention are used for household cleaning, medical cleaning, facility cleaning such as cleaning in schools, airports, and hospitals, or industrial cleaning.

[0504] The enzyme detergents and cleaning compositions or products according to the present invention can be prepared by combining and mixing various components according to commonly known methods. Preferably, the enzyme is added last to prevent denaturation or inactivation of the enzyme. Mixing can be carried out by any suitable automatic or manual method. For example, automatic or manual stirring can be performed. The enzyme detergent compositions can be prepared in a batch process or a continuous process.

[0505] Based on the aforementioned advantageous effects, detergents and cleaning compositions according to the present invention, comprising a combination of an enzyme and an enzyme stabilizer such as an alkanediol, glyceryl caprylate, 4-hydroxyacetophenone, ethylhexylglycerin, and / or tropolone, are particularly efficient in cleaning and washing processes for efficiently removing dyes and / or stains from substrates.

[0506] Therefore, in a further embodiment, the present invention relates to a method for treating a stained and / or soiled substrate, - A step of treating a substrate with a detergent and cleaning composition or product according to the present invention; and -The method comprises the step of rinsing the aforementioned substrate in water to remove the aforementioned composition or product.

[0507] Preferably, the method for treating a soiled / stained substrate is carried out in a wash containing a washing solution comprising water and an enzymatic detergent and washing composition according to the present invention. The washing solution may be applied to the substrate or the substrate may be immersed in the washing solution.

[0508] Alternatively, the method may involve directly applying an enzyme detergent and cleaning composition, i.e., an enzyme detergent and cleaning composition not dissolved without water, to part or all of the substrate in order to directly treat stains and / or dirt on the substrate. Such a process is preferably a pretreatment, which may be followed by treatment with or in a cleaning solution.

[0509] The method according to the present invention is applicable to both higher and lower temperatures. For dishwashing applications, for example, washing substrates at temperatures above about 60°C, above about 70°C, or between about 65°C and 80°C. For laundry applications, for example, washing laundry at temperatures above about 40°C, above about 50°C, or between about 65°C and 90°C.

[0510] Preferably, this method is applied at a low temperature where staining and / or stain removal is more problematic. Preferably, the processing temperature is below 50°C, preferably below 40°C, and more preferably below 30°C.

[0511] The enzyme detergents and cleaning compositions according to the present invention are particularly efficient in removing stains and / or dirt at low temperatures as described above.

[0512] Therefore, the method allows for the enzymatic removal of stains and / or contaminants in a low-temperature range without considering the temperature sensitivity of the enzymes used.

[0513] This is particularly advantageous in the treatment of sensitive substrates that can only be washed or cleaned at low temperatures, such as wool, silk, and synthetic fibers like polyester, polyacrylic, and nylon.

[0514] Preferably, the base material is cotton.

[0515] More preferably, the base material is wool or silk.

[0516] More preferably, the base material is a blended fabric such as cotton and polyester, or a synthetic fiber such as polyester, polyacrylic, or nylon.

[0517] Advantageously, based on the enzyme stabilizing effect, as described above, the present invention further relates to enzyme stabilizers, (b I) A mixture comprising at least one linear alkanediol having a carbon chain of 5 to 14 carbon atoms as defined herein, or at least one first linear alkanediol having a carbon chain of 5 to 14 carbon atoms and one or more second linear alkanediols having carbon chains of 5 to 14 carbon atoms different from the first linear alkanediol; (b II ) Glyceryl caprylate; (bIII) 4-hydroxyacetophenone; (b IV Ethylhexylglycerin; (b V ) Tropolone; and Regarding the use of at least one enzyme stabilizer selected from the group consisting of any mixture thereof; Its use is to stabilize enzymes in detergents and cleaning compositions.

[0518] With regard to enzyme stabilizers and their preferred modifications, refer to the above description relating to detergents and cleaning compositions according to the present invention, which is equally effective with respect to the use of at least one enzyme stabilizer for stabilizing enzymes in detergents and cleaning compositions, in order to avoid repetition.

[0519] With respect to enzymes and their preferred modifications, refer to the above description of enzymes related to detergents and cleaning compositions according to the present invention, which is equally effective with respect to the use of at least one enzyme stabilizer (b) for stabilizing the enzymes in detergents and cleaning compositions, in order to avoid repetition.

[0520] Preferably, the enzyme is selected from the group consisting of proteases, amylases, lipases, cellulases, cutinases, gluconases, peroxidases, pectinases, mannanases, esterases, hemicellulases, xylanases, phospholipases, pectinate lyases, keratinases, reductases, nucleases (including DNases and / or RNases), phenol oxidases, lipoxygenases, ligninases, pullulanases, tannases, pentosanases, maranases, β-glucanases, arabinosidases, hyaluronidases, chondroitinases, oxidoreductases, and any mixtures thereof.

[0521] More preferably, the enzyme is selected from the group consisting of proteases, amylases, lipases, cellulases, mannanases, pectin lyases, and any mixture thereof.

[0522] Surprisingly, the use of at least one enzyme stabilizer identified herein has been found to stabilize enzymes in detergents and cleaning compositions during storage, resulting in better cleaning performance compared to detergents and cleaning compositions that do not contain the aforementioned enzyme stabilizers.

[0523] Therefore, the use of the aforementioned substances enables the stabilization of enzymes in detergents and cleaning compositions, particularly during storage. This excellent effect is based on the combination of enzymes and enzyme stabilizers that provides superior enzyme stabilization.

[0524] Due to the improved enzyme stabilization effect, the amount of enzyme in enzyme-containing detergents and cleaning compositions can be reduced, thereby largely eliminating or at least reducing the use of further enzyme stabilizers while providing stabilized enzyme detergents and cleaning compositions.

[0525] Furthermore, surprisingly, at least one of the enzyme stabilizers identified herein can be used as an enzyme stabilizer in place of a commercially available enzyme stabilizer (described earlier as a further enzyme stabilizer), and thus the composition can use fewer enzyme stabilizers, such as components containing borates, in smaller amounts.

[0526] As described above regarding enzyme stabilizers, based on their advantageous enzyme stabilization effect, the present invention finally provides a method for stabilizing enzymes in detergents and cleaning compositions, i. A step of providing detergents and cleaning compositions containing enzymes; ii. (b I ) A mixture comprising at least one linear alkanediol having a carbon chain of 5 to 14 carbon atoms as defined herein, or at least one first linear alkanediol having a carbon chain of 5 to 14 carbon atoms and one or more second linear alkanediols having carbon chains of 5 to 14 carbon atoms different from the first linear alkanediol; (b II ) Glyceryl caprylate; (b III )4-hydroxyacetophenone; (b IV Ethylhexylglycerin; (b V ) Tropolone; and The present invention relates to a method comprising the step of adding an effective amount of at least one enzyme stabilizer selected from the group consisting of any mixtures thereof.

[0527] With regard to enzyme stabilizers and their preferred modifications, refer to the above description relating to detergents and cleaning compositions according to the present invention, which is equally effective with respect to the use of at least one enzyme stabilizer for stabilizing enzymes in detergents and cleaning compositions, in order to avoid repetition.

[0528] With respect to enzymes and their preferred modifications, refer to the above description of enzymes related to detergents and cleaning compositions according to the present invention, which is equally effective with respect to methods for stabilizing enzymes in detergents and cleaning compositions to avoid repetition.

[0529] Preferably, the enzyme is selected from the group consisting of proteases, amylases, lipases, cellulases, cutinases, gluconases, peroxidases, pectinases, mannanases, esterases, hemicellulases, xylanases, phospholipases, pectinate lyases, keratinases, reductases, nucleases (including DNases and / or RNases), phenol oxidases, lipoxygenases, ligninases, pullulanases, tannases, pentosanases, maranases, β-glucanases, arabinosidases, hyaluronidases, chondroitinases, oxidoreductases, and any mixtures thereof.

[0530] More preferably, the enzyme is selected from the group consisting of proteases, amylases, lipases, cellulases, mannanases, pectin lyases, and any mixture thereof.

[0531] During storage, the enzymes contained in detergents and cleaning compositions are damaged, for example, by inactivation, denaturation, or disintegration, by physical influences such as temperatures exceeding 35°C, or by oxidation or proteolytic cleavage. Subsequently, the detergents and cleaning compositions lose their enzymatic properties.

[0532] Surprisingly, it has been found that adding at least one enzyme stabilizer in an effective amount as defined herein to enzyme-containing detergents and cleaning compositions has a positive effect in that it significantly slows the rate of enzyme inactivation by efficiently stabilizing the enzyme. The enzymes in these detergents and cleaning compositions exhibit excellent stability during storage and therefore maintain their performance over time. More specifically, the enzyme detergents and cleaning compositions exhibit stability after being stored for at least two weeks at temperatures above standard ambient temperature (25°C), particularly above 35°C.

[0533] Therefore, the addition of one of the aforementioned enzyme stabilizers to detergents and cleaning compositions is beneficial in a method for stabilizing the enzymes contained therein during storage. The combination of the enzyme stabilizer and enzyme of the present invention contributes to more effective enzyme stabilization during storage and results in improved cleaning performance of the detergents and cleaning compositions compared to detergents and cleaning compositions that do not contain the aforementioned enzyme stabilizer.

[0534] In addition, based on the improved enzyme stability, especially during storage, the enzyme can function for a longer period and therefore provide higher cleaning efficacy by effectively removing stains and / or dirt.

[0535] Conversely, due to the excellent stability of the enzyme, the amount of enzyme or further enzyme stabilizers and other components to increase enzyme stability in these detergents and cleaning compositions can be reduced without compromising cleaning performance.

[0536] In its final embodiment, the present invention provides an enzyme composition, (A) at least one enzyme; (B) (B I A mixture comprising at least one first linear alkanediol having a carbon chain of 5 to 14 carbon atoms, and one or more second linear alkanediols having a carbon chain of 5 to 14 carbon atoms different from that of the first linear alkanediol; (B II ) Glyceryl caprylate; (B III )4-hydroxyacetophenone; (B IV Ethylhexylglycerin; (B V ) Tropolone; and At least one enzyme stabilizer selected from the group consisting of any mixture thereof; and (C) The present invention relates to an enzyme composition comprising or comprising at least one further enzyme stabilizer different from enzyme stabilizer (B).

[0537] With respect to enzyme (A) and its preferred modifications, to avoid repetition, the above description of enzymes relating to detergents and cleaning compositions according to the present invention is provided for reference, which is equally valid in relation to enzyme compositions.

[0538] Preferably, the enzyme (A) in the enzyme composition is selected from the group consisting of proteases, amylases, lipases, cellulases, cutinases, gluconases, peroxidases, pectinases, mannanases, esterases, hemicellulases, xylanases, phospholipases, pectinate lyases, keratinases, reductases, nucleases (including DNase and / or RNase), phenol oxidases, lipoxygenases, ligninases, pullulanases, tannases, pentosanases, maranases, β-glucanases, arabinosidases, hyaluronidases, chondroitinases, oxidoreductases, and any mixtures thereof.

[0539] With regard to enzyme stabilizer (B) and its preferred modifications, refer to the above description of enzyme stabilizers relating to detergents and cleaning compositions according to the present invention, which is equally valid in relation to enzyme compositions, in order to avoid repetition.

[0540] In a preferred modification, the enzyme stabilizer (B) is selected from the group consisting of glyceryl caprylate, 4-hydroxyacetophenone, ethylhexylglycerin, tropolone, a mixture containing 1,2-alkanediol and 2,3-alkanediol, a mixture containing 1,2-hexanediol and 1,2-octanediol, a mixture containing 1,2-hexanediol and 1,2-octanediol and tropolone, a mixture containing 4-hydroxyacetophenone and 1,2-octanediol, and any mixture thereof.

[0541] In a favorable modification, the enzyme composition according to the present invention comprises one of the following combinations of components (A) and (B): • Protease + one or more of the following enzyme stabilizers: (B I) A mixture comprising at least one first linear alkanediol having a carbon chain of 5 to 14 carbon atoms as defined above, and one or more second linear alkanediols having a carbon chain of 5 to 14 carbon atoms different from that of the first linear alkanediol; (B II ) Glyceryl caprylate; (B III )4-hydroxyacetophenone; (B IV ) Ethylhexylglycerin; or (B V ) Tropolon; or • Lipase + one or more of the following enzyme stabilizers: (B I ) A mixture comprising at least one first linear alkanediol having a carbon chain of 5 to 14 carbon atoms as defined above, and one or more second linear alkanediols having a carbon chain of 5 to 14 carbon atoms different from that of the first linear alkanediol; (B II ) Glyceryl caprylate; (B III )4-hydroxyacetophenone; (B IV ) Ethylhexylglycerin; or (B V ) Tropolon; or • Amylase + one or more of the following enzyme stabilizers: (B I ) A mixture comprising at least one first linear alkanediol having a carbon chain of 5 to 14 carbon atoms as defined above, and one or more second linear alkanediols having a carbon chain of 5 to 14 carbon atoms different from that of the first linear alkanediol; (B II ) Glyceryl caprylate; (B III )4-hydroxyacetophenone; (B IV ) Ethylhexylglycerin; or (B V ) Tropolon; or • Cellulase + one or more of the following enzyme stabilizers: (B I ) A mixture comprising at least one first linear alkanediol having a carbon chain of 5 to 14 carbon atoms as defined above, and one or more second linear alkanediols having a carbon chain of 5 to 14 carbon atoms different from that of the first linear alkanediol; (B II ) Glyceryl caprylate; (B III)4-hydroxyacetophenone; (B IV ) Ethylhexylglycerin; or (B V ) Tropolon; or • Mannanase + one or more of the following enzyme stabilizers: (B I ) A mixture comprising at least one first linear alkanediol having a carbon chain of 5 to 14 carbon atoms as defined above, and one or more second linear alkanediols having a carbon chain of 5 to 14 carbon atoms different from that of the first linear alkanediol; (B II ) Glyceryl caprylate; (B III )4-hydroxyacetophenone; (B IV ) Ethylhexylglycerin; or (B V ) Tropolon; or • Pectin lyase + one or more of the following enzyme stabilizers: (B I ) A mixture comprising at least one first linear alkanediol having a carbon chain of 5 to 14 carbon atoms as defined above, and one or more second linear alkanediols having a carbon chain of 5 to 14 carbon atoms different from that of the first linear alkanediol; (B II ) Glyceryl caprylate; (B III )4-hydroxyacetophenone; (B IV ) Ethylhexylglycerin; or (B V ) Tropolon.

[0542] In a more preferred variation, the enzyme composition according to the present invention comprises one of the following combinations of components (A) and (B): • Protease + Glyceryl Caprylate; • Protease + 4-hydroxyacetophenone; • Protease + ethylhexylglycerin; • Protease + tropolone; • A mixture containing protease, 1,2-hexanediol, and 1,2-octanediol; • A mixture containing protease, 1,2-hexanediol, 1,2-octanediol, and tropolone; • A mixture containing protease, 4-hydroxyacetophenone, and 1,2-octanediol; • Amylase + Glyceryl Caprylate; Amylase + 4-hydroxyacetophenone; • Amylase + Ethylhexylglycerin; • Amylase + Tropolone; • A mixture containing amylase, 1,2-hexanediol, and 1,2-octanediol; • A mixture containing amylase, 1,2-hexanediol, 1,2-octanediol, and tropolone; • A mixture containing amylase, 4-hydroxyacetophenone, and 1,2-octanediol; • Lipase + Glyceryl Caprylate; • Lipase + 4-hydroxyacetophenone; • Lipase + ethylhexylglycerin; • Lipase + tropolone; • A mixture containing alipase, 1,2-hexanediol, and 1,2-octanediol; • A mixture containing lipase, 1,2-hexanediol, 1,2-octanediol, and tropolone; • A mixture containing lipase, 4-hydroxyacetophenone, and 1,2-octanediol; Mannanase + Glyceryl Caprylate; Mannanase + 4-hydroxyacetophenone; Mannanase + ethylhexylglycerin; • Mannanase + Tropolone; • A mixture containing mannanase, 1,2-hexanediol, and 1,2-octanediol; • A mixture containing mannanase, 1,2-hexanediol, 1,2-octanediol, and tropolone; • A mixture containing mannanase, 4-hydroxyacetophenone, and 1,2-octanediol; • Pectin lyase + glyceryl caprylate; • Pectin lyase + 4-hydroxyacetophenone; • Pectin lyase + ethylhexylglycerin; Pectin lyase + tropolone; • A mixture containing pectin lyase, 1,2-hexanediol, and 1,2-octanediol; • A mixture containing pectin lyase + 1,2-hexanediol and 1,2-octanediol and tropolone; or A mixture containing pectinate lyase, 4-hydroxyacetophenone, and 1,2-octanediol.

[0543] The combinations of enzyme (A) and enzyme stabilizer (B) identified above were found to provide excellent enzyme stability in the enzyme composition / formulation, particularly during storage.

[0544] With regard to further enzyme stabilizers (C) and preferred modifications thereof, refer to the above description of further enzyme stabilizers relating to detergents and cleaning compositions according to the present invention, which are equally valid in relation to enzyme compositions, in order to avoid repetition.

[0545] In preferred variations, the enzyme stabilizer (C) is selected from the group consisting of polyols, e.g., glycols, e.g., monopropylene glycol, glycerin, mannitol, isomaltol, sorbitol, xylitol, treitol, erythritol, arabitol; amino alcohols, e.g., mono-, di-, triethanolamine and -propanolamine; aliphatic carboxylic acids up to C12, e.g., succinic acid and its salts; dicarboxylic acids and their salts; terminally capped fatty acid amide alkoxylates; salts, preferably calcium and magnesium salts, e.g., calcium chloride, calcium formate, magnesium chloride, magnesium formate; reversible enzyme inhibitors, e.g., borate-containing compositions, e.g., 4-FBPA; boron-free inhibitors, e.g., disubstituted alaninamide, sodium formate; and any mixture thereof.

[0546] The present invention will be described in detail with reference to the following examples, but these examples are merely illustrative and the content of the present invention is not limited to the following examples. [Examples]

[0547] Example 1: The following tests are conducted to demonstrate the stabilizing effect of different enzyme stabilizers according to the present invention on the stability of different enzymes, and therefore on the cleaning performance of the detergents and cleaning compositions according to the present invention.

[0548] The detergents and cleaning compositions include laundry detergents, hand dishwashing detergents, and automatic dishwashing detergents.

[0549] For this purpose, samples of detergents and cleaning compositions according to the present invention, containing enzymes or enzyme mixtures and enzyme stabilizers, are stored for 2 weeks, 4 weeks, 6 weeks, and 12 weeks.

[0550] The enzymes in detergents and cleaning compositions are selected from proteases, amylases, lipases, or cellulases due to their different sensitivities (e.g., protease sensitivity, amylase sensitivity).

[0551] Each sample is also stored at different storage temperatures, namely 4°C, 20°C, and 35°C.

[0552] In parallel, the same comparative tests will be conducted under the same conditions for detergents and cleaning compositions containing the same enzyme or enzyme mixture but without an enzyme stabilizer.

[0553] The cleaning performance of the detergent and cleaning composition according to the present invention, as well as comparative detergent and cleaning compositions, is tested before storage and after storage for 2 weeks, 4 weeks, 6 weeks, and 12 weeks, as described below.

[0554] [Example 1.1] Laundry detergent The cleaning performance of laundry detergents will be analyzed according to the AISE standard (International Association of Soaps, Detergents and Maintenance Products) Laundry Detergent Testing Guidelines.

[0555] The washing performance test consists of evaluating the stain removal effectiveness of the tested laundry detergent against 14 different dyes.

[0556] Test conditions: Washing machine, Miele European Household front loader Water hardness: 2.5 mmol / l Water temperature: 40℃ Washing cycle: 6 cycles (heavy-duty detergent: cotton cycle; Light-duty detergent (for delicate cycles) Ballast load: 3kg, Clean White ballast load Ballast soil: 4 SBL 2004 sheets (100% cotton, approximately 8g of soiling per swatch) Dosage: Recommended dosage for normal / medium hardness soiling. Drying: Leave out overnight. Dyeing set: Brown, Chocolate, Coffee, Grass, Red Wine, Grass / Mud, Fruit Juice, Blood, Tomato Puree, Unused Motor Oil, Balsamic Salad Dressing, Cooked Beef Tallow, French Squeezed Mustard, and Makeup.

[0557] Measurement / evaluation is performed for each dye before washing (to verify the quality of the dyeing) and after washing.

[0558] The degree of stain removal can be evaluated by one of the following methods: (B) Sensory panel (Scale 1-10: Scale 1: No cleaning; Scale 10: Complete removal) (C) Spectrophotometer or digital image analysis system for determining the stain removal index (SRI) whiteness W

[0559] The results are statistically analyzed using Tukey's HSD test (HSD = truly significant difference) at a 95% confidence level. The HSD value highlights significant differences between each pair of products.

[0560] [Examples 1 and 2] Dishwashing detergent The cleaning performance of dishwashing detergents is analyzed in accordance with the IKW recommendations for quality assessment of the cleaning performance of dishwashing detergents.

[0561] The test involves measuring the efficiency of dishwashing detergents through the stability of their foam while washing plates coated with a typical mixture of liquids, proteins, and carbohydrates (foaming test; foam duration).

[0562] Test conditions: Water hardness: 16±2°d Water temperature: 45±1℃ Test stains: (1) Low-fat stains: Composition as specified in the IKW recommendations; and (2) Normal soiling: Composition as specified in the IKW Recommendations The dirt is coated onto the center of the plate by an automatic dispenser. Dishwashing process: As described in the IKW recommendations.

[0563] Endpoint Identification: The dishwashing solution was considered exhausted and the endpoint reached when the foam layer permanently decomposed on the surface of the dishwashing solution. Record the number of plates washed per wash test in the test protocol.

[0564] For each type of stain, five washing tests will be conducted on each test product.

[0565] The products are compared based on the number of plates washed until the bubbles collapsed. Turkey's HSD statistical test is performed with a 95% confidence level.

[0566] [Example 1.3] Dishwashing detergent The cleaning performance of dishwashing detergents is analyzed in accordance with the IKW recommendations for quality assessment of the cleaning performance of dishwashing detergents.

[0567] The washing performance test consists of evaluating the stain removal effectiveness of the tested laundry detergent against 14 different dyes.

[0568] Test conditions: Washing machine, Miele dishwasher GSL or Miele GSL 2 Water hardness: For classic products: 1.8 mmol / l For multi-functional products: 3.5 mmol / l Water temperature: 45℃ during the main wash cycle Wash cycle: at least 3 cycles Dosage: Recommended dosage for normal / medium hardness soiling. Dyeing kit: Black tea (bleachable), Milk, milk skin (persistent / alkaline sensitive), Starch mix, pasta (starch-containing, amylase-sensitive), Egg yolk, cream blue, ground meat (protein-containing, protease-sensitive) Number of soiled items: 6 of each type

[0569] Measurement / evaluation is performed for each stain by either visual inspection with reference to a photographic catalog or by gravimetric measurement, as described in the IKW recommendations.

[0570] The results obtained are statistically processed using Tukey's HSD test (HSD = truly significant difference) at a 95% confidence level. The HSD value highlights significant differences between each pair of products.

[0571] As can be seen from the above tests, the detergents and cleaning compositions according to the present invention exhibit superior cleaning performance even after 12 weeks of storage compared to the cleaning performance without the enzyme stabilizer of the present invention. Conversely, this means that the enzymes in the detergents and cleaning compositions are stabilized by the addition of the enzyme stabilizer of the present invention during storage, whereas the enzyme performance of detergents and cleaning compositions without the enzyme stabilizer deteriorates over time.

[0572] Example 2: Evaluation of the enzyme stability of the enzyme detergent and laundry composition according to the present invention regarding stain removal performance. The following tests were conducted to demonstrate the stabilizing effect of different enzyme stabilizers on the stability of different enzymes in detergents and cleaning compositions before and after a one-month storage period at 40°C, with respect to stain removal performance.

[0573] To evaluate the stain removal performance of laundry detergents, laundry detergent compositions were tested in combination with different enzyme stabilizers. The laundry detergent compositions were blended with different enzyme stabilizers as shown in the table below and evaluated compared to a laundry detergent composition without enzyme stabilizers (placebo) according to the spectrophotometric measurements described below.

[0574] The stain removal efficacy was tested according to the following test protocol.

[0575] Principle: The test consists of evaluating the stain removal efficacy of test detergents against 12 different dyes. The fabric dyes are artificially applied to specific fabric types and allowed to cure for a predetermined period of time. The size of each dye sample is specified to allow for reproducible readings (50 mm in diameter). These dye swatches are washed / immersed in the test detergents being compared, and the relative degree of stain removal is evaluated. The test allows for a comparison of the stain removal capabilities of products under the same conditions.

[0576] Dye selection: Standardized, off-the-shelf multi-sample and multi-spot monitors were used to test the effectiveness of the tested detergents (selected and manufactured by Warwick Equest and CFT).

[0577] Dyeing instructions: CS-44 Chocolate Drink, Pure, Cotton, ·CS-07 grass, pure, cotton top, • PC-05 Blood, milk, ink (BMI), polyester / cotton top, ·WE5DASB Double Application Sheep Blood, Knitted Cotton, CS-68 chocolate ice cream, aged, cottony, • E-165 Chocolate pudding, on top of cotton, E-161 starch, cotton, CS-27 potato starch, coloring, cotton, CS-62 lard, colored with Sudan Red, on cotton, ·C-H126 "Vegetable oil", colored with purple dye, on cotton, • C-H141 sugar-free pectin, on cotton, C-H147 "Jam," forest fruit, on cotton.

[0578] The stains are manufactured using a reproducible method and have consistent quality. The stains are a mixture of "natural stains" and "standardized stains." The stains are uniformly distributed and colored before and after washing. Therefore, 12 different stain formulations can be tested simultaneously in a single test process. Certain stains are particularly sensitive to the enzymes specified in the table below.

[0579] [Table 1]

[0580] Test conditions: Each of the 12 dyed test sample groups was immersed in a metal wash pot containing 833.3 g of test laundry detergent solution at a temperature of 40°C for 30 minutes.

[0581] 833.3g of laundry detergent solution is composed of the following dilutions: 3g of liquid laundry detergent with a hardness of 15°Hf.

[0582] Stir the test solution using Rotawash M228B / C.

[0583] After the test cycle is complete, remove the stained material from the wash pot and then lay it horizontally to dry.

[0584] Measurement / Evaluation: The average reflectance of the fabric is measured using a Ci62 spectrophotometer before the fabric is stained, after staining, and again after being treated with the test laundry detergent and washed. Three measurements are taken for each staining process. Product performance is evaluated by the instrument in terms of the Stain Removal Index (SRI). The SRI is on a scale of 0 to 100, where 0 means no stain removal and 100 means complete stain removal.

[0585] As stated in ASTM D4265, the SRI is calculated according to the following formula:

[0586]

number

[0587] The value ΔE (absolute color difference) is calculated as follows:

[0588]

number

[0589] The tested laundry detergent compositions were compared to each other as follows: The higher the SRI, the better the washing performance, i.e., the better the stain removal performance.

[0590] To test the stabilizing efficacy of different enzyme stabilizers, enzyme-containing laundry detergent formulations were used with the following compositions:

[0591] [Table 2]

[0592] The aforementioned laundry detergent formulations were mixed with different enzyme stabilizers according to the present invention, and their stain removal performance was evaluated according to the test method described above, as shown in the table below.

[0593] The stain removal performance of each test sample was measured before storage (t=0) and after a 1-month storage period (t=1 month). The test samples were stored in an oven (in the dark) at a temperature of 40°C.

[0594] Regarding the evaluation of enzyme stabilization effect: The lower the delta-SRI between SRI(t=0) and SRI(t=1 month), the better the enzyme stabilization effect of the tested enzyme stabilizer.

[0595] In the following table, the following abbreviations will be used: C5 = 1,2-pentanediol C6=1,2-Hexanediol C7 = 1,2-heptanediol C8 = 1,2-octanediol C10 = 1,2-decanediol 4HAP = 4-hydroxyacetophenone

[0596] 2.1 Stain removal performance of different 1,2-alkanediols against amylase-sensitive staining

[0597] [Table 3]

[0598] As can be seen from Table 1, the addition of 1,2-alkanediols to detergents and laundry compositions results in improved enzyme stability against amylase-sensitive stains compared to detergents and laundry compositions without enzyme stabilizers. Surprisingly, the addition of 1,2-hexanediol, 1,2-heptanediol, and 1,2-decanediol provides a better stabilization effect compared to 1,2-pentanediol. Therefore, the stability of enzyme-containing detergents and laundry compositions can be significantly improved by adding 1,2-hexanediol, 1,2-heptanediol, or 1,2-decanediol to detergents or laundry formulations. The best enzyme stabilization effect in terms of stain removal efficacy is shown for amylase-sensitive stains with respect to 1,2-hexanediol.

[0599] 2.2 Removal performance of different 1,2-alkanediols from lipase-sensitive stains

[0600] [Table 4]

[0601] As can be seen from Table 2, the addition of 1,2-alkanediols to detergents and laundry compositions results in improved enzyme stability for protease-sensitive staining compared to detergents and laundry compositions without enzyme stabilizers. Surprisingly, the addition of 1,2-hexanediol, 1,2-heptanediol, and 1,2-octanediol provides a better stabilizing effect compared to 1,2-pentanediol. Therefore, the stability of enzyme-containing detergents and laundry compositions can be significantly improved by adding 1,2-hexanediol, 1,2-heptanediol, or 1,2-octanediol to detergents or laundry formulations.

[0602] 2.3 Stain removal performance of a mixture of 4-HAP and 1,2-alkanediol against lipase-sensitive staining

[0603] [Table 5]

[0604] As can be seen from Table 3, the addition of either 4-hydroxyacetophenone alone or a mixture of 4-hydroxyacetophenone and 1,2-alkanediol to detergent and cleaning compositions results in an enzyme-stabilizing effect compared to detergent and cleaning compositions with any of the additions.

[0605] 2.4 Stain removal performance of 1,2-alkanediols or mixtures of 1,2-alkanediols against protease-sensitive staining

[0606] [Table 6]

[0607] As can be seen from Table 4, the addition of 1,2-alkanediols to detergents and laundry compositions results in improved enzyme stability for protease-sensitive staining compared to detergents and laundry compositions without enzyme stabilizers. Surprisingly, the addition of 1,2-heptanediol or 1,2-decanediol provides a better stabilizing effect compared to 1,2-pentanediol. Therefore, the stability of enzyme-containing detergents and laundry compositions can be significantly improved by adding 1,2-heptanediol or 1,2-decanediol to detergents or laundry formulations.

[0608] Surprisingly, mixtures of two different 1,2-alkanediols, such as a mixture of 1,2-pentanediol and 1,2-heptanediol or a mixture of 1,2-decanediol and 1,2-heptanediol, exhibit a synergistic enzyme stabilization effect compared to the use of a single 1,2-alkanediol.

[0609] 2.5 Stain removal performance of a mixture of 4-HAP and 1,2-alkanediol against protease-sensitive staining

[0610] [Table 7]

[0611] As can be seen from Table 5, the addition of either 4-hydroxyacetophenone alone or a mixture of 4-hydroxyacetophenone and 1,2-alkanediol to detergent and cleaning compositions provides an enzyme-stabilizing effect compared to detergent and cleaning compositions with the addition of any enzyme stabilizer. The enzyme-stabilizing effect of the mixture of 4-hydroxyacetophenone and 1,2-alkanediol is even better, i.e., synergistic, compared to the enzyme-stabilizing effect of using a single substance.

[0612] As can be seen from the results above, adding the enzyme stabilizers specified in this application to enzyme detergents and cleaning compositions, either alone or as a mixture of two enhancers, significantly improves enzyme stability. The detergents and cleaning compositions exhibit excellent enzyme stability after storage, even at low addition rates of the enzyme stabilizers or mixtures thereof. Due to the reduced enzyme inactivation after storage, the detergents and cleaning compositions according to the present invention show less or no decrease in cleaning performance compared to detergents and cleaning compositions without such enzyme stabilizers.

[0613] Example 3: Analytical enzyme stability The effects of different enzyme stabilizers and their concentrations on enzyme stability will be evaluated using enzyme assays.

[0614] Enzyme assays are established, standardized experimental protocols for measuring the activity or concentration of enzymes in biochemical systems. Most enzyme assays are based on the detection of fluorescence, luminescence, or spectrophotometric endpoint signals.

[0615] The enzyme stabilizers according to the present invention and the enzymes specified herein are tested in a suitable buffer solution.

[0616] Three different enzymes, namely protease, amylase, and lipase, will be tested.

[0617] Enzyme compositions were prepared by varying the concentration of the enzyme stabilizer. The amount of enzyme in the buffer system was kept constant.

[0618] The samples are analyzed for enzyme stability using an appropriate enzyme assay. The stability results for each enzyme tested are collected.

[0619] Next, the formulation samples were stored at different storage temperatures, namely 4°C, 20°C, and 35°C, for periods of 2 weeks, 4 weeks, 6 weeks, and 12 weeks. Then, each sample of the tested formulation was collected and analyzed by enzyme assay.

[0620] As can be seen from the results, the tested enzymes retained their enzymatic activity even after 12 weeks of storage. These results demonstrate that the enzyme stabilizer of the present invention provides enzyme activity retention. (a)

[0621] Example 4: Formulation Example

[0622] [Table 8]

[0623] [Table 9]

[0624] [Table 10]

[0625] [Table 11]

[0626] [Table 12]

[0627] [Table 13]

[0628] [Table 14]

[0629] [Table 15]

[0630] [Table 16]

Claims

1. Detergents and cleaning compositions, (a) at least one enzyme; (b) (b Ｉ A mixture comprising at least one linear alkanediol having a carbon chain of 6 to 14 carbon atoms, or at least one first linear alkanediol having a carbon chain of 5 to 14 carbon atoms, and one or more second linear alkanediols having carbon chains of 5 to 14 carbon atoms different from the first linear alkanediol; (b ＩＩ ) Glyceryl caprylate; (b ＩＩＩ ) 4-hydroxyacetophenone; (b ＩＶ Ethylhexylglycerin; (b Ｖ ) Tropolone; and At least one enzyme stabilizer selected from the group consisting of any mixture thereof; (c) a surfactant in an amount exceeding 3% by weight based on the total weight of the composition; and (d) A detergent and cleaning composition comprising or comprising at least one further enzyme stabilizer different from the enzyme stabilizer (b).

2. The detergent and cleaning composition according to claim 1, wherein the at least one enzyme is selected from the group consisting of protease, amylase, lipase, cellulase, cutinase, gluconase, peroxidase, pectinase, mannanase, esterase, hemicellulase, xylanase, phospholipase, pectinate lyase, keratinase, reductase, nuclease (including DNase and / or RNase), phenol oxidase, lipoxygenase, ligninase, pullulanase, tannase, pentosanase, maranase, β-glucanase, arabinosidase, hyaluronidase, chondroitinase, oxidoreductase, and any mixture thereof.

3. The at least one linear alkanediol or the first linear alkanediol is selected from the group consisting of 1,2-pentanediol, 2,3-pentanediol, 1,2-hexanediol, 2,3-hexanediol, 1,2-heptanediol, 2,3-heptanediol, 1,2-octanediol, 2,3-octanediol, 1,2-nonanediol, 2,3-nonanediol, 1,2-decanediol, 2,3-decanediol, 1,2-undecanediol, 2,3-undecanediol, 1,2-dodecanediol, 2,3-dodecanediol, 1,2-tridecanediol, 2,3-tridecanediol, 1,2-tetradecanediol, 2,3-tetradecanediol, and any mixture thereof; and / or The detergent and cleaning composition according to claim 1 or 2, wherein the second linear alkanediol is selected from the group consisting of 1,2-pentanediol, 2,3-pentanediol, 1,2-hexanediol, 2,3-hexanediol, 1,2-heptanediol, 2,3-heptanediol, 1,2-octanediol, 2,3-octanediol, 1,2-nonanediol, 2,3-nonanediol, 1,2-decanediol, 2,3-decanediol, 1,2-undecanediol, 2,3-undecanediol, 1,2-dodecanediol, 2,3-dodecanediol, 1,2-tridecanediol, 2,3-tridecanediol, 1,2-tetradecanediol, 2,3-tetradecanediol, and any mixture thereof.

4. The at least linear alkanediol is selected from the group consisting of 1,2-pentanediol, 1,2-hexanediol, 1,2-heptanediol, 1,2-octanediol, 1,2-nonanediol, 1,2-decanediol, 1,2-undecanediol, 1,2-dodecanediol, 1,2-tridecanediol, 1,2-tetradecanediol, and any mixture thereof; or The linear alkanediol is selected from the group consisting of 2,3-pentanediol, 2,3-hexanediol, 2,3-heptanediol, 2,3-octanediol, 2,3-nonanediol, 2,3-decanediol, 2,3-undecanediol, 2,3-dodecanediol, 2,3-tridecanediol, 2,3-tetradecanediol, and any mixture thereof; or The mixture comprising at least one first linear alkanediol and one or more second linear alkanediols A mixture containing 1,2-pentanediol and 2,3-pentanediol; A mixture containing 1,2-hexanediol and 2,3-hexanediol; A mixture containing 1,2-heptanediol and 2,3-heptanediol; A mixture containing 1,2-octanediol and 2,3-octanediol; A mixture containing 1,2-nonanediol and 2,3-nonanediol; A mixture containing 1,2-decanediol and 2,3-decanediol; A mixture containing 1,2-undecanediol and 2,3-undecanediol; A mixture containing 1,2-dodecanediol and 2,3-dodecanediol; A mixture containing 1,2-tridecanediol and 2,3-tridecanediol; A mixture containing 1,2-tetradecanediol and 2,3-tetradecanediol; A mixture containing 1,2-hexanediol and 1,2-octanediol; A mixture containing 1,2-hexanediol and 2,3-octanediol; A mixture containing 1,2-octanediol and 2,3-hexanediol; A mixture containing 1,2-octanediol and 2,3-heptanediol; A mixture containing 1,2-pentanediol and 2,3-hexanediol; A mixture containing 1,2-pentanediol and 2,3-heptanediol; A mixture containing 1,2-pentanediol and 2,3-octanediol; A mixture containing 1,2-pentanediol and 1,2-nonanediol; A mixture containing 1,2-pentanediol and 2,3-nonanediol; A mixture containing 1,2-heptanediol and 1,2-pentanediol; A mixture containing 1,2-heptanediol and 1,2-hexanediol; A mixture containing 1,2-heptanediol and 1,2-octanediol; A mixture containing 1,2-heptanediol and 2,3-octanediol; A mixture containing 1,2-heptanediol and 1,2-nonanediol; A mixture containing 1,2-heptanediol and 2,3-nonanediol; A mixture containing 1,2-heptanediol and 1,2-decanediol; A mixture containing 1,2-heptanediol and 1,2-undecanediol; A mixture containing 1,2-heptanediol and 1,2-dodecanediol; and The detergent and cleaning composition according to claim 3, selected from the group consisting of a mixture comprising 1,2-heptanediol and 1,2-tridecanediol.

5. The detergent and cleaning composition according to any one of claims 1 to 4, wherein the mixture comprising at least one first linear alkanediol and one or more second linear alkanediols comprises the first linear alkanediol and the second alkanediol in a ratio in the range of 50:50 to 99.9:0.1, preferably in the range of 75:25 to 99:1, more preferably in the range of 80:20 to 98:2, and even more preferably in the range of 90:10 to 95:

5.

6. The at least one surfactant is selected from the group consisting of anionic surfactants, cationic surfactants, nonionic surfactants, amphoteric / zwitterionic surfactants, and any mixture thereof; preferably - The anionic surfactant is C10-C18 alkylbenzene sulfonates; C10-C18 alkyl sulfates; - C10-C18 alkyl sulfates ethoxylated with 1-3 moles of ethylene oxide; C10-C18 alpha-olefin sulfonates; - C8-C18 alkylcarboxylates ethoxylated with 1-10 moles of ethylene oxide; and selected from the group consisting of any mixture thereof; The cationic surfactant, • Quaternary C8-C18 alkylethanolamines; • Quaternary C8-C18 alkylammonium compounds; C8-C18 alkylammonium methosulfates; and selected from the group consisting of any mixture thereof; - The nonionic surfactant is - C6-C18 fatty alcohols ethoxylated with 1-12 moles of ethylene oxide; ・Alkoxylated C6-C18 fatty alcohols, for example C6-C18 fatty alcohols ethoxylated with 1-25 moles of ethylene oxide, C6-C18 fatty alcohols propoxylated with 1-15 moles of propylene oxide, C6-C18 fatty alcohols butoxylated with 1-10 moles of butylene oxide, and their combinations; C6-C18 sophorolipids; C6-C18 rhamnolipids; C5-C18 alkyl polyglycosides; C6-C18 alkanolamides; C6-C18 fatty acid ester alkoxylates; and selected from the group consisting of any mixture thereof; and - The aforementioned amphoteric / zwitterionic surfactant, C10-C18 N-(alkyl)-N,N-dimethylamine oxide; C10-C18 N-(alkyl)-N,N-bis(2-hydroxyethyl)amine oxide; C10-C18 alkylamidopropyldimethylamine oxide; C10-C18 alkylbetaines; C10-C18 alkylamide betaines; C10-C18 sulfobetaine; Selected from the group consisting of any mixture thereof; The detergent and cleaning composition according to any one of claims 1 to 5, wherein the mixture is any mixture of the above-mentioned cationic, anionic, nonionic, and amphoteric / zwitterionic surfactants.

7. The detergent and cleaning composition according to any one of claims 1 to 6, wherein the at least one further enzyme stabilizer is selected from the group consisting of polyols, e.g. glycols, e.g. monopropylene glycol, glycerin, mannitol, isomaltol, sorbitol, xylitol, treitol, erythritol, arabitol; amino alcohols, e.g. mono-, di-, triethanolamine and -propanolamine; aliphatic carboxylic acids up to C12, e.g. succinic acid and its salts; dicarboxylic acids and their salts; terminally capped fatty acid amide alkoxylates; salts, preferably calcium and magnesium salts, e.g. calcium chloride, calcium formate, magnesium chloride, magnesium formate; reversible enzyme inhibitors, e.g. borate-containing compositions, e.g. 4-FBPA; boron-free inhibitors, e.g. disubstituted alaninamide, sodium formate; and any mixture thereof; preferably, the at least one further enzyme stabilizer is calcium chloride or sodium formate.

8. Detergents and cleaning compositions according to any one of claims 1 to 7, further comprising active substances and / or additives selected from the group consisting of solvents, builders, bleaches, stain removers, dispersants, anti-foaming agents, metal ion sequestering agents, chelating agents, anti-redeposition agents, anti-color transfer / color protection agents, dye scavengers, dyes, anti-graying agents, fluorescent whitening agents, ultraviolet light absorbers, thickeners or rheological modifiers, hydrotropes, solubility modifiers, pH adjusters, buffers, solvents, antistatic agents, anti-wrinkle agents, antimicrobial agents, odor removers / odor scavengers, ultraviolet light protection agents, fragrances, bactericides, disinfectants, water repellents, insect repellents, anti-pilling agents, scouring agents, antifungal agents, anti-allergic agents, and any mixtures thereof.

9. The chelating agent is selected from the group consisting of ethylenediaminetetraacetic acid (EDTA), diethylenetriaminepentamethylenephosphonic acid (DTMPA, DTPMP), hydroxyethanediphosphonic acid (HEDP), ethylenediamine N,N-disuccinic acid (EDDS), methylglycinediacetic acid (MGDA), diethylenetriaminepentaacetic acid (DTPA), propylenediaminetetraacetic acid (PDTA), 2-hydroxypyridine-N-oxide (HPNO), methylglycinediacetic acid (MGDA), glutamic acid N,N-diacetic acid (N,N-dicarboxymethylglutamate tetrasodium salt (GLDA)), nitrilotriacetic acid (NTA), citrate, and mixtures thereof; preferably, the chelating agent is hydroxyethanediphosphonic acid (HEDP); and / or The detergent and cleaning composition according to claim 8, wherein the antimicrobial agent is selected from the group consisting of benzyl alcohol, methylbenzyl alcohol, phenoxyethanol, and any mixture thereof.

10. The enzyme is included in an amount of 0.0001 to 5% by weight, preferably 0.0001 to 4% by weight, more preferably 0.001 to 3% by weight, even more preferably 0.01 to 2% by weight, and most preferably 0.05 to 2% by weight, based on the total weight of the composition; and / or Based on the total weight of the composition, the composition contains at least one enzyme stability enhancer (b) in an amount of 0.001 to 15.0% by weight, preferably 0.01 to 10.0% by weight, more preferably 0.1 to 5.0% by weight, even more preferably 0.3 to 3.0% by weight, and most preferably 0.5 to 1.0% by weight; and / or Based on the total weight of the composition, the composition contains at least one surfactant in an amount of 4 to 90% by weight, preferably 10 to 60% by weight, more preferably 20 to 50% by weight, and most preferably 30 to 40% by weight; and / or The detergent and cleaning composition according to any one of claims 1 to 9, comprising, based on the total weight of the composition, at least one further enzyme stabilizer in an amount of 0.0001 to 5% by weight, preferably 0.001 to 4% by weight, and most particularly 0.01 to 3% by weight.

11. Use of the detergent and cleaning composition according to any one of claims 1 to 10, preferably as a detergent and cleaning product for washing textiles, laundry, fabric care, dishwashing, household, institutional and industrial hard surface cleaning, and cleaning medical and dental instruments, or for the preparation of detergent and cleaning products.

12. A detergent and cleaning product comprising a detergent and cleaning composition according to any one of claims 1 to 11, wherein the detergent and cleaning composition or product is a heavy-duty detergent, a color care detergent, a light-duty detergent, a general-purpose detergent, a fabric softener, a fabric laundry fragrance, a fragrance lotion, laundry wipes, a dye and / or stain remover (Press Potter, Vanish type), a degreasing cleaner, a washing machine cleaner, a home care product, a general-purpose cleaner, a hand dishwashing detergent, an automatic dishwashing detergent, a hard surface cleaner, a glass and mirror cleaner, a wet cleaning wipe, a kitchen cleaner, a cookware cleaner. Detergents and cleaning products, including cleaners, oven cleaners, floor cleaners, wood floor cleaners, carpet cleaners, bathroom and shower cleaners, toilet cleaners, grout cleaners, disinfectants, drain cleaners, toilet rim block gels, air fresheners, furniture polishes, and car shampoos; medical cleaning products, all of the aforementioned products in liquid, solid, gel, stick, paste, spray, tablet, encapsulated, diluted or concentrated forms, and optionally in two-compartment or multi-compartment forms; and all of the aforementioned products for household, medical, institutional or industrial use.

13. The use of at least one enzyme stability enhancer, (b Ｉ ) A mixture comprising at least one linear alkanediol having a carbon chain of 5 to 14 carbon atoms as defined in any one of claims 3 to 5, or at least one first linear alkanediol having a carbon chain of 5 to 14 carbon atoms and one or more second linear alkanediols having carbon chains of 5 to 14 carbon atoms different from the first linear alkanediol; (b ＩＩ ) Glyceryl caprylate; (b ＩＩＩ ) 4-hydroxyacetophenone; (b ＩＶ ) ethylhexyl glycerin; (b Ｖ ) Tropolone; and Selected from the group consisting of any mixture thereof; Use for stabilizing enzymes in detergents and cleaning compositions.

14. A method for stabilizing enzymes in detergents and cleaning compositions, (i) A step of providing a detergent and cleaning composition containing an enzyme; (ii) In addition, an effective amount of 1,2-heptanediol or 2,3-heptanediol, or a mixture containing 1,2-heptanediol and 2,3-heptanediol, (b Ｉ ) A mixture comprising at least one linear alkanediol having a carbon chain of 5 to 14 carbon atoms as defined in any one of claims 3 to 5, or at least one first linear alkanediol having a carbon chain of 5 to 14 carbon atoms and one or more second linear alkanediols having carbon chains of 5 to 14 carbon atoms different from the first linear alkanediol; (b ＩＩ ) Glyceryl caprylate; (b ＩＩＩ ) 4-hydroxyacetophenone; (b ＩＶ Ethylhexylglycerin; (b Ｖ ) Tropolone; and A method comprising the step of adding at least one enzyme stabilizer (b) selected from the group consisting of any mixture thereof.

15. An enzyme composition, (A) at least one enzyme; (B) (B Ｉ A mixture comprising at least one first linear alkanediol having a carbon chain of 5 to 14 carbon atoms, and one or more second linear alkanediols having a carbon chain of 5 to 14 carbon atoms different from the first linear alkanediol; (B ＩＩ ) Glyceryl caprylate; (B ＩＩＩ ) 4-hydroxyacetophenone; (B ＩＶ Ethylhexylglycerin; (B Ｖ ) Tropolone; and At least one enzyme stabilizer selected from the group consisting of any mixture thereof; and (C) An enzyme composition comprising or comprising at least one further enzyme stabilizer different from the enzyme stabilizer (B).

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