Viruses produced by Nannochloropsis, and methods and compositions for producing them.
Nannochloropsis microalgae-based expression cassettes address scalability and cost issues in AAV vector production, providing efficient and cost-effective recombinant AAV vectors for gene therapy and vaccines.
JP2026517793APending Publication Date: 2026-06-02INSMED INC
Patent Information
- Authority / Receiving Office
- JP · JP
- Patent Type
- Applications
- Current Assignee / Owner
- INSMED INC
- Filing Date
- 2024-05-03
- Publication Date
- 2026-06-02
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Figure 2026517793000001_ABST
Abstract
This disclosure relates in part to a Nannochloropsis microalga that produces recombinant viruses. Expression cassettes, transgenes, and methods for producing recombinant viruses in Nannochloropsis are also provided. In particular, methods and materials for producing recombinant adeno-associated virus (AAV) in Nannochloropsis are provided. In some embodiments described herein, Nannochloropsis is Nannochloropsis oceanica.
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