Small molecule enhancer for adeno-associated virus production
Small molecule enhancers like compound A to G and SAHA improve AAV production efficiency and stability across serotypes and cell variants, addressing the limitations of serotype-specific enhancers and enhancing compatibility with transfection reagents.
JP2026517819APending Publication Date: 2026-06-02MIRUS BIO CORP
Patent Information
- Authority / Receiving Office
- JP · JP
- Patent Type
- Applications
- Current Assignee / Owner
- MIRUS BIO CORP
- Filing Date
- 2024-05-01
- Publication Date
- 2026-06-02
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Figure 2026517819000001_ABST
Abstract
This specification describes a method for producing adeno-associated virus (AAV) using an enhancer that enables increased AAV production. The use of such enhancers to increase AAV production using transfection reagents is also described herein.
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