Silicon phthalocyanine dyes and silicon tribenzophthalocyanine dyes, and their use in diagnosis and therapy
JP2026521099APending Publication Date: 2026-06-26ALBERT LUDWIGS UNIV FREIBURG
Patent Information
- Authority / Receiving Office
- JP · JP
- Patent Type
- Applications
- Current Assignee / Owner
- Filing Date
- 2024-03-21
- Publication Date
- 2026-06-26
AI Technical Summary
Technical Problem
Existing silicon phthalocyanine dyes for photodynamic therapy lack the ability to effectively penetrate deep into tissue and target specific biological structures, limiting their therapeutic efficacy.
Method used
Development of novel silicon tribenzophthalocyanine dyes with a 3:1 naphthalocyanine/phthalocyanine hybrid core, covalently bonded to molecules like antibodies, which absorb light in the red to near-infrared region and are water-soluble, allowing deeper tissue penetration and targeted photodynamic therapy.
Benefits of technology
The new dyes enable deeper tissue penetration and enhanced therapeutic effects by generating singlet oxygen, effectively destroying targeted cells and inducing an immune response, particularly in tumors.
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Abstract
This application relates to a novel A3B type silicon phthalocyanine containing a new silicon tribenzophthalocyanine dye.
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Citation Information
Patent Citations
Phthalocyanine dyes
US7005518B2
Phthalocyanine dye compounds, conjugates and methods of use thereof
WO2021207691A1