Silicon phthalocyanine dyes and silicon tribenzophthalocyanine dyes, and their use in diagnosis and therapy

JP2026521099APending Publication Date: 2026-06-26ALBERT LUDWIGS UNIV FREIBURG

Patent Information

Authority / Receiving Office
JP · JP
Patent Type
Applications
Current Assignee / Owner
ALBERT LUDWIGS UNIV FREIBURG
Filing Date
2024-03-21
Publication Date
2026-06-26

AI Technical Summary

Technical Problem

Existing silicon phthalocyanine dyes for photodynamic therapy lack the ability to effectively penetrate deep into tissue and target specific biological structures, limiting their therapeutic efficacy.

Method used

Development of novel silicon tribenzophthalocyanine dyes with a 3:1 naphthalocyanine/phthalocyanine hybrid core, covalently bonded to molecules like antibodies, which absorb light in the red to near-infrared region and are water-soluble, allowing deeper tissue penetration and targeted photodynamic therapy.

Benefits of technology

The new dyes enable deeper tissue penetration and enhanced therapeutic effects by generating singlet oxygen, effectively destroying targeted cells and inducing an immune response, particularly in tumors.

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Patent Text Reader

Abstract

This application relates to a novel A3B type silicon phthalocyanine containing a new silicon tribenzophthalocyanine dye.
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