Containment structure with sterile working room

Abstract

The subject of the present invention is a containment (1) structure comprising a sterile work chamber (14) and a decontamination device (6) associated with the work chamber (14). The work chamber (14) is defined below by a base (12). Above the work chamber (14) is a circulating air area (15) in which circulating air filters (2, 2') are arranged together with a circulating air fan (3). The circulating air area (15) and the work chamber (14) are delimited from the outside by a housing (10). At least one return air duct (16) leads from the work chamber (14) to the circulating air area (15). Return air filters (5, 5') are fluidically connected to the return air duct (16), i.e., are arranged facing the circulating air area (15). The return air filters (5, 5') can be arranged at the opening of the return air duct (16) to the recirculation air area (15) or recessed within the return air duct (16). The return air filters (5, 5') or recirculation air filters (2, 2') can have the form of plate filters or replaceable filter cartridges (5', 2') or replaceable filter inserts. In this case, a single return air filter (5, 5') or a series of interacting return air filters (5, 5') or a single recirculation air filter (2, 2') or a series of interacting recirculation air filters (2, 2') can be installed. Containments (1) that can process a larger volume of air additionally have a second return air duct (17) in which or within which a return air filter (5, 5') is also installed.

Description

[Technical field]

[0001] Use of the invention The subject of the invention is a containment design with a sterile work chamber and a decontamination device associated with the work chamber. The work chamber is delimited below by a bottom, and a circulation air area is located above the work chamber, in which a circulation air filter is arranged together with a circulation air fan. The circulation air area and the work chamber are delimited from the outside by a housing. From the work chamber, at least one first return air duct leads to the circulation air area. A return air filter is connected in a fluid technical manner to the return air duct. Such an installation is used for processing sterilized objects. During the processing, contaminating particles must not reach the processed object from the outside. In particular, isolators, for example for the pharmaceutical chemical industry, are recognized as containments. The term further includes all types of RABS (Restricted Access Barrier System). [Background technology]

[0002] In the applicant's EP 3170545 A1 an exemplary construction of the containment is shown. On the front side, a transparent shield is fitted with a glove grip so that the user can see through and has an approach to the work chamber with gloves. The laminar air flow introduced into the work chamber is purified by a filter unit via a return air duct and led into a circulating air area located above the work chamber. The filter unit, for example in the form of a filter cartridge, is inserted in the return air duct at the enlarged inlet, thus allowing convenient handling when changing the filters. If the dimensions of the enlarged inlet are set larger, however, this may not result in completely ideal ergonomics for the user at the work area in front of the containment.

[0003] EP 2 666 532 discloses a somewhat different construction of containment, in which two return air ducts are provided to return the laminar air flow introduced into the working chamber to a circulating air area arranged above the working chamber, and at the inlet openings of the return air ducts a filter unit is installed in each case, the filter units being located at the bottom of the working chamber. However, this reduces the space available in the working chamber for the equipment positioned therein, and the user must stretch further forward with his gloves beyond the filter units to reach any point, for example a processing machine. [Prior art documents] [Patent documents]

[0004] [Patent Document 1] European Patent Application Publication No. 3170545 [Patent Document 2] European Patent No. 2666532 Summary of the Invention [Problem to be solved by the invention]

[0005] Starting from the known background art, the problem underlying the present invention is to design the constructional structure of a containment with a sterile working chamber in a more ergonomically optimal manner for the user working in the containment, while optimally utilizing the space available in the working chamber for operation and installation of equipment. Ultimately, the design of clean room technology should lead to efficient operation and installation costs. [Means for solving the problem]

[0006] The subject of the present invention is a containment design with a sterile work chamber and a decontamination device associated with the work chamber. The work chamber is delimited below by a bottom, and above the work chamber a circulation air area is located, in which a circulation air filter is arranged together with a circulation air fan. The circulation air area and the work chamber are delimited from the outside by a housing. From the work chamber, at least one first return air duct leads to the circulation air area. The return air filter is connected in a fluid technical sense to the return air duct, i.e. is arranged facing the circulation air area.

[0007] In the following, special embodiments of the invention are defined: the return air filter can be arranged at the opening of the return air duct to the circulation air area or recessed from the opening in the return air duct, the opening of the return air duct which accommodates the return air filter can be configured as a protrusion which extends the circulation air area or protrudes into the circulation air area, or can have no protrusion and transition to the circulation air area with an approximately straight cross section.

[0008] The return air filter or circulating air filter may have the form of a plate filter or an exchangeable filter cartridge or a replaceable filter insert, whereby a single return air filter or a series of interacting return air filters may be provided, or a single circulating air filter or a series of interacting circulating air filters may be installed.

[0009] At least a first return air duct comprises as components a transparent front shield and a transparent duct shield spaced apart from the front shield, and has an inlet opening located above and near the base.

[0010] Between the circulating air area and the working chamber an air guide element extends, which serves to generate a uniform exhaust flow (laminar flow) flowing downstream in the working chamber.

[0011] The decontamination device has a vaporizer or at least one spray nozzle positioned in the circulating air area, to which the decontamination agent is supplied by a pump via a substance conduit, the spray nozzle spraying the decontamination agent as an aerosol by compressed air.

[0012] At least one spray nozzle comprises: Directed into the workroom, and / or into an intermediate space located between the circulating air area and the air guide element, and / or Directed into at least one return air duct.

[0013] When operating the containment in decontamination mode with the vaporizer as part of the decontamination system, the circulating air fan is controlled at reduced power, for example 50%.

[0014] Depending on the size and purpose of the working chamber, it is possible to provide a series of spray nozzles directed into the working chamber. When operating the containment in the decontamination mode with the spray nozzles in the decontamination device, the circulating air fan is controlled at least to the extent that no volume flow is sent. Advantageously, the spray nozzles are arranged offset from one another so that the aerosol introduced as decontamination agent circulates in the working chamber.

[0015] To further perfect the structure, the cleaning nozzle is Directed into the workroom, and / or into an intermediate space located between the circulating air area and the air guide element, and / or It is directed against the flow direction at least in the first return air duct, i.e. before the return air filter.

[0016] Return air duct The cleaning nozzles directed into the working chamber and / or into the intermediate space are advantageously mounted in a fixed position, while the cleaning nozzles directed into the working chamber are alternatively attached to the spray gun.

[0017] In particular, containments for special purposes or with a larger amount of treated air additionally have a second return air duct, which has a wall portion of the housing and a duct wall spaced apart from the wall portion, and which also has an inlet opening located above and close to the bottom. The return air filter associated with the second return air duct is also arranged facing the circulation air area, i.e. at the opening of the second return air duct into the circulation air area or directly in the second return air duct. The opening of the second return air duct, which accommodates the return air filter, can likewise be formed as a protrusion extending the circulation air area or protruding into the circulation air area, or does not have a protrusion and transitions into the circulation air area with an approximately straight cross section. As for the first return air duct, the return air filter for the second return air duct has the form of a plate filter or an exchangeable filter cartridge or a replaceable filter insert.

[0018] When a second return air duct is provided, the circulating air filter can also be provided as a plate filter or an exchangeable filter cartridge or a replaceable filter insert. In this case, a single return air filter or a series of interacting return air filters can be provided, or a single circulating air filter or a series of interacting circulating air filters can be installed. As in the first return air duct, spray nozzles and washing nozzles can also be installed in the second return air duct. [Brief description of the drawings]

[0019] The containment structure with a sterile working chamber according to the invention is shown in various embodiments, each as a principle diagram. [Figure 1] A first embodiment is shown having one return air duct having a protrusion that protrudes into the circulating air area, a return air filter installed therein, a circulating air filter, and a vaporizer as components of the decontamination apparatus. [Diagram 2] 2 shows a second embodiment of the structure according to FIG. 1 with two return air ducts. [Diagram 3]A third embodiment is shown having one return air duct with a protrusion that expands the circulating air area, a return air filter installed therein, a circulating air filter, and a spray nozzle as components of the decontamination device. [Figure 4] A fourth embodiment is shown having two return air ducts, each having a protrusion that protrudes into the circulating air area, a return air filter installed therein, a circulating air filter, and a spray nozzle as components of the decontamination device. [Diagram 5] A fifth embodiment of the structure according to FIG. 4 is shown, which has two return air ducts, each having a protrusion that expands the circulating air area, a return air filter installed therein, and a spray nozzle as a component of the decontamination device. [Figure 6] FIG. 6 shows a sixth embodiment of the arrangement according to FIG. 5 with one replaceable filter cartridge in each case as return air filter. [Figure 7] FIG. 7 shows a seventh embodiment having two return air ducts each with one replaceable filter cartridge as return air filters, an arranged series of replaceable filter cartridges as circulating air filters, and a spray nozzle as a component part of the decontamination device. DETAILED DESCRIPTION OF THE PREFERRED EMBODIMENTS

[0020] With reference to the accompanying drawings, a detailed description of the structure of a containment with a sterile working chamber according to the invention in various exemplary embodiments is given below.

[0021] In all the following description, the following provisions apply: In the figures, reference numbers are provided for clarity of illustration, whereby if it is clearly discernible that a "repeated" component from the figures is not mentioned in the directly corresponding description, this is for the sake of brevity, and reference is made to the description of the preceding figures.

[0022] FIG. 1. First embodiment In a vertical position, seen from below, the containment 1 is structured in a substructure 13, a working chamber 14 located thereon, an intermediate space 11 located thereon and a circulation air area 15 arranged at the very top. The working chamber 14, the intermediate space 11 and the circulation air area 15 are delimited towards the outside by the housing 10. On the lower side, the working chamber 14 ends in a bottom 12 and on the upper side in an air guide element 9 configured as a laminar flow device, here a so-called CG distributor in the form of a mesh-type sterile air distributor. An air supply unit 18 and an exhaust unit 19, each consisting of a fan and a filter, are connected to the circulation air area 15. Via the air supply unit 18, the air circulating in the containment 1 in the operating mode is supplied with a portion of treated fresh air into the circulation air area 15, and a portion of the fresh air is led off from the circulation air area 15 via the exhaust unit 19. In the circulating air area 15, a circulating air fan 3 and a circulating air filter 2 (here in the form of a plate filter) are arranged. In the operating mode, the circulating air fan 3 draws air from the circulating air area 15, feeds it through the circulating air filter 2 into the intermediate space 11 and subsequently through the air guide element 9 tensioned therebelow as a uniform discharge flow, called laminar flow for short LF, which flows downstream in the working chamber 14 towards the bottom 12. In the working chamber 14, at least one processing machine 8, for example a filling machine, is often arranged vertically, usually on the bottom 12.

[0023] The containment 1 has at least a first return air duct 16, which is surrounded at the front 100 by a part of the housing 10 and a transparent front shield 4 on the one hand, and by a transparent duct shield 40 on the other hand, the front shield 4 and the duct shield 40 together are often referred to in the industry as a double shield. On the front 100, a pair of work gloves 7 is usually attached, which allows the user to enter the work room 14 in a protected manner. The return air duct 16 extends from near the bottom 12, which here has an inlet opening 160, to the circulation air area 15. The opening of the return air duct 16 into the circulation air area 15, i.e. the protrusion 161 protruding into the circulation air area 15 in this example, is currently fitted with a HEPA plate filter ( H igh E efficiencies P Articulate A A return air filter 5 in the form of a return air filter (return air filter) is installed in the containment 1. Due to the feeding action of the return air fan 3, air circulates in the containment 1 in the operating mode from the return air area 15 via the working room 14 and back to the return air area 15 through the return air duct 16, with the air led off via the exhaust unit 19 being partially replaced by treated fresh air introduced by the intake unit 18. In this case, the return air filter 5 has two functions. Firstly, particles containing impurities possibly carried with the return air flow from the working room 14 are separated in the return air filter 5. Secondly, particles containing impurities possibly occurring cannot pass from the return air area 15 through the return air filter 5, which also acts as a backflow prevention device, in particular against the circulating air flow, into the working room 14 via the return air duct 16.

[0024] To carry out the decontamination steps, the containment 1 is equipped with a decontamination device 6. In the depicted embodiment, it is provided with a vaporizer 60 positioned in the circulating air area 15, into which a decontamination agent, preferably H 2 , is pumped by a pump 64 from a storage container 63 via a substance conduit 62. 2 O 2In the decontamination mode, the circulating air fan 3 is controlled at reduced power, for example 50%.

[0025] FIG. 2 Second embodiment The difference with respect to the first embodiment according to Fig. 1 is only that here a second return air duct 17 is additionally provided, which has a wall part of the housing 10 and a duct wall 4' spaced apart therefrom and has an inlet opening 170. The inlet opening 170 is again located above and close to the bottom 12. In this case a return air filter 5 is also installed at the opening of the second return air duct 17 into the circulation air area 15, i.e. also at the projection 171 projecting into the circulation air area 15. Such a second return air duct 17 is designed in containments 1 in which larger air quantities are treated.

[0026] FIG. 3 Third embodiment The difference with respect to the first embodiment according to FIG. 1 lies in the form of the opening of the return air duct 16 into the circulation air area 15, i.e. here as a protrusion 161 in which the return air filter 5 is installed, which extends the circulation air area 15, so that the circulation air filter 2 can extend in a fluid-technically advantageous manner over the entire width of the working chamber 14 here.

[0027] Furthermore, the decontamination device 6 is based here on a spray nozzle 61, by means of which the supply of decontamination agent and compressed air +P, which is fed via a substance conduit 62 and a pump 64, is sprayed as an aerosol. Depending on the design of the containment 1, at least one spray nozzle 61 directed into the working chamber 14 may be of primary importance. When the working chamber 14 is larger, it may be necessary to provide several spray nozzles 61 opening into the working chamber 14. In this case, the spray nozzles 61 are advantageously arranged offset from one another so that the aerosol introduced as decontamination agent circulates in the working chamber 14. When operating the containment 1 in the decontamination mode with the spray nozzle 61, the circulating air fan 3 is switched off completely or controlled to such an extent that no volume flow is fed. Depending on the size and use of the containment 1, in the intermediate space 11 and / or in the return air duct 16, a further spray nozzle 61 each with a feed conduit 62 for the substance and compressed air +P can additionally be positioned.

[0028] FIG. 4 Fourth embodiment Here, mixed forms of construction of the containment 1 are depicted. Due to the second embodiment according to Fig. 2, two return air ducts 16, 17 with respective inlet openings 160, 170 and two projections 161, 171 projecting into the circulating air area 15, each with a return air filter 5 mounted therein, are provided. Due to the third embodiment according to Fig. 3, a decontamination device 6 is provided with a spray nozzle 61, a conduit 62 for the substance and a supply of compressed air +P.

[0029] FIG. 5 Fifth embodiment In contrast to the preceding design according to Figure 4, here, like the principle based on the design according to Figure 3, the openings of the two return air ducts 16, 17 into the circulation air area 15 are configured as projections 161, 171 which widen the circulation air area 15, in which the return air filters 5 are respectively arranged. This allows the circulation air filters 2 to be arranged here too optimally over the entire width of the working chamber 14 in terms of fluid technology.

[0030] FIG. 6 Sixth embodiment This construction is a variant of the arrangement according to Fig. 5, where instead of the return air filter 5 in the form of a plate filter, which was previously mounted in the respective expanding projection 161, 171, an exchangeable filter cartridge 5' is used here. Furthermore, a cleaning nozzle 69 opens out into each projection 161, 171 respectively on the underside of the filter cartridge 5'. In addition, at least one cleaning nozzle 69 is directed into the working chamber 14.

[0031] FIG. 7 Seventh embodiment In this design, there are again two return air ducts 16, 17. The return air ducts 16, 17, however, do not have any protrusions and transition into the circulation air area 15 with an approximately straight cross section. In each return air duct 16, 17, recessed at the transition to the circulation air area 15, a replaceable filter cartridge is installed as the return air filter 5'. The circulation air filter 2' here consists of a series of arranged replaceable filter cartridges. Here too, a cleaning nozzle 69 is directed into the corresponding return air duct 16, 17, respectively, below the filter cartridge 5', i.e. against the flow direction. In addition to the embodiment according to FIG. 6, at least one cleaning nozzle 69 is also provided here, which is directed into the intermediate space 11. In this case, instead of the air guide element in the form of a CG distributor, which was used up until now, an air guide element 9' in the form of a perforated plate is used here, due to its relatively high resistance to cleaning fluids. For ease of handling, the cleaning nozzles 69 directed towards the return air ducts 16, 17 or towards the intermediate space 11 are mounted in a fixed position, while the cleaning nozzles 69 directed into the working chamber 14 are preferably mounted on spray guns. The overall decontamination device 6 is identical to the configuration according to figures 3 to 6. This application relates to the invention described in the claims, but also includes the following as other aspects. 1. A containment structure (1) comprising a sterile work chamber (14) and a decontamination device (6) associated with the work chamber (14), a) the working chamber (14) has a bottom (12) at its lower side; b) a circulating air area (15) is located above the working chamber (14), in which circulating air filters (2, 2') are arranged together with a circulating air fan (3), c) the circulating air area (15) and the working chamber (14) are defined with respect to the outside by the housing (10); d) from the working room (14) at least one return air duct (16) leads to the circulating air area (15); e) the return air filter (5, 5') is fluidically connected to the return air duct (16); In the structure, f) A construction of the containment (1), characterized in that the return air filters (5, 5') are arranged facing the circulating air area (15). 2. 2. The structure according to claim 1, characterized in that the return air filter (5, 5') is arranged at the opening of the return air duct (16) into the circulating air area (15) or in the return air duct (16). 3. An opening of the return air duct (16) that houses the return air filter (5, 5') a) it is configured as a protrusion (161) which extends the circulating air area (15) or which protrudes into the circulating air area (15), or b) transition into the circulating air area (15) with a substantially straight cross section without any protrusions 3. The structure of claim 2. 4. a) the return air filter (5, 5') is in the form of a plate filter or an exchangeable filter cartridge (5') or a replaceable filter insert; b) The circulating air filters (2, 2') have the form of plate filters or exchangeable filter cartridges (2') or replaceable filter inserts. 4. Any one of the structures 1 to 3 above. 5. a) a single return air filter (5, 5') or a series of interacting return air filters (5, 5') are provided, b) A single circulating air filter (2, 2') or a series of interacting circulating air filters (2, 2') are installed; 5. Any one of the structures 1 to 4 above. 6. At least the first return air duct (16) a) having as its components a transparent front shield (4) and a transparent duct shield (40) spaced apart from the front shield (4); b) having an inlet opening (160), the inlet opening (160) being located above and near the bottom (12); 6. Any one of the structures 1 to 5 above, characterized in that 7. 7. The construction according to any one of claims 1 to 6, characterized in that between the circulating air area (15) and the working chamber (14) an air guide element (9, 9') extends, which serves to generate a uniform discharge flow (LF) flowing downstream in the working chamber (14). 8. The decontamination device (6) a) having a vaporizer (60) positioned in the circulating air area (15) to which the decontamination agent is supplied via a substance conduit (62); or b) having at least one spray nozzle (61), to which a decontamination agent is supplied via a conduit (62) for the substance; At this time, at least one spray nozzle (61) c) directed into the working chamber (14); and / or d) directed into the intermediate space (11) located between the circulating air area (15) and the air guide element (9, 9'), and / or e) directed into at least one return air duct (16); 8. Any one of the structures 1 to 7 above, characterized in that 9. The structure of claim 8, wherein when the containment (1) is operated in a decontamination mode using the vaporizer (60) in the decontamination apparatus (6), the output of the circulating air fan (3) is controlled to be reduced, for example, to 50%. 10. a) a series of spray nozzles (61) directed into the working chamber (14); b) when the containment (1) is operated in decontamination mode using the spray nozzles (61) in the decontamination device (6), the circulating air fan (3) is controlled at least to such an extent that no volumetric flow is delivered, c) The spray nozzles (61) are offset from one another so that the aerosol introduced as the decontamination agent circulates within the working chamber (14). 9. The structure of claim 8. 11. a) the decontamination agent is fed by a pump (64) via a substance conduit (62) to a vaporizer (60) positioned in the circulating air area (15), or b) A decontamination agent is supplied to at least one spray nozzle (61) via a substance conduit (62), which is then pumped by a pump (64) and sprayed as an aerosol by compressed air (+P). 11. The structure of any one of claims 8 to 10. 12. A cleaning nozzle (69) a) directed into the working chamber (14); and / or b) directed into the intermediate space (11) located between the circulating air area (15) and the air guide element (9, 9'), and / or c) directed against the flow direction at least in the first return air duct (16), i.e. before the return air filter (5, 5'); 12. The structure of any one of claims 1 to 11 above. 13. a) the cleaning nozzles (69) directed into the return air duct (16) and / or into the intermediate space (11) are fixed in position, while b) The cleaning nozzle (69) directed into the working chamber (14) is fixed in position or attached to a spray gun. 12. The structure of claim 12, 14. A second return air duct (17) is additionally provided, a) the second return air duct (17) has a wall portion of the housing (10) and a duct wall portion (4') spaced apart from the wall portion, and has an inlet opening (170) located above and near the bottom portion (12); b) the return air filter (5, 5') faces the circulating air area (15), i.e. is located at the opening of the second return air duct (17) to the circulating air area (15) or in the second return air duct (17), c) the opening of the second return air duct (17), which accommodates the return air filter (5, 5'), can be formed as a protrusion (171) extending the circulating air area (15) or protruding into the circulating air area (15), or it does not have a protrusion and transitions into the circulating air area (15) with an approximately straight cross section; d) the return air filter (5, 5') is in the form of a plate filter or an exchangeable filter cartridge (5') or a replaceable filter insert; e) the circulating air filter (2, 2') is in the form of a plate filter or an exchangeable filter cartridge (2') or a replaceable filter insert; f) a single return air filter (5, 5') or a series of interacting return air filters (5, 5') are provided, g) A single circulating air filter (2, 2') or a series of interacting circulating air filters (2, 2') are installed. 14. The structure of any one of claims 1 to 13. 15. a) the spray nozzle (61) is directed into the second return air duct (17); b) The cleaning nozzle (69) is directed into the second return air duct (17), i.e. before the return air filter (5, 5') against the flow direction. 15. The structure of claim 14,

Claims

1. A containment structure (1) comprising a sterile work chamber (14) and a decontamination device (6) associated with the work chamber (14), a) the working chamber (14) has a bottom (12) at the bottom, b) a circulating air area (15) is located above the working chamber (14), in which a circulating air filter (2, 2') is arranged together with a circulating air fan (3), c) the circulating air area (15) and the working chamber (14) are delimited with respect to the outside by the housing (10), d) from the working room (14) at least one return air duct (16) leads to the circulating air area (15); e) the return air filter (5, 5') is fluidically connected to the return air duct (16); In the structure, f) A construction of the containment (1), characterized in that the return air filter (5, 5') is arranged facing the circulation air area (15) at the opening of the return air duct (16) into the circulation air area (15).

2. an opening of the return air duct (16) housing the return air filter (5, 5'), a) is configured as a protrusion (161) which extends the circulating air area (15) or protrudes into the circulating air area (15), or b) transition into the circulating air area (15) with a substantially straight cross section without any protrusions 2. The structure of claim 1 .

3. a) the return air filter (5, 5') is in the form of a plate filter or an exchangeable filter cartridge (5') or a replaceable filter insert; b) the circulating air filter (2, 2') has the form of a plate filter or an exchangeable filter cartridge (2') or a replaceable filter insert; 3. A structure according to claim 1 or 2, characterized in that

4. a) a single return air filter (5, 5') or a series of interacting return air filters (5, 5') are provided, b) A single circulating air filter (2, 2') or a series of interacting circulating air filters (2, 2') are installed. A structure according to any one of claims 1 to 3, characterized in that

5. At least a first return air duct (16) comprises: a) comprising as components a transparent front shield (4) and a transparent duct shield (40) spaced apart from the front shield (4); b) having an inlet opening (160), the inlet opening (160) being located above and near the bottom (12); A structure according to any one of claims 1 to 4, characterized in that

6. 6. The arrangement according to claim 1, characterized in that between the circulating air area (15) and the working chamber (14) there extend air guide elements (9, 9'), which serve to generate a laminar flow (LF) downstream in the working chamber (14).

7. The decontamination device (6) a) having a vaporizer (60) positioned in the circulating air area (15), the vaporizer (60) being supplied with a decontamination agent via a substance conduit (62), or b) having at least one spray nozzle (61), to which a decontamination agent is supplied via a conduit (62) for the substance; At this time, at least one spray nozzle (61) c) directed into the working chamber (14); and / or d) directed into the intermediate space (11) located between the circulating air area (15) and the air guide element (9, 9'), and / or e) directed into at least one return air duct (16); A structure according to any one of claims 1 to 6, characterized in that

8. 8. The arrangement according to claim 7, characterized in that when the containment (1) is operated in a decontamination mode using the vaporizer (60) in the decontamination device (6), the circulating air fan (3) is controlled at reduced power.

9. a) a series of spray nozzles (61) directed into the working chamber (14); b) when the containment (1) is operated in decontamination mode using the spray nozzles (61) in the decontamination device (6), the circulating air fan (3) is controlled at least to such an extent that no volumetric flow is delivered, c) The spray nozzles (61) are arranged offset from one another so that the aerosol introduced as the decontamination agent circulates in the working chamber (14).

8. The structure of claim 7.

10. a) the decontamination agent is fed by a pump (64) via a substance conduit (62) to a vaporizer (60) positioned in the circulating air area (15), or b) the decontamination agent is fed via a substance conduit (62) to at least one spray nozzle (61), which is pumped by a pump (64) and sprayed as an aerosol by compressed air (+P); A structure according to any one of claims 7 to 9, characterized in that

11. A cleaning nozzle (69) a) directed into the working chamber (14); and / or b) directed into the intermediate space (11) located between the circulating air area (15) and the air guide element (9, 9'), and / or c) directed against the flow direction at least in the first return air duct (16), i.e. before the return air filter (5, 5'); A structure according to any one of claims 1 to 10, characterized in that

12. a) the cleaning nozzles (69) directed into the return air duct (16) and / or into the intermediate space (11) are installed in a fixed position, while b) A cleaning nozzle (69) directed into the working chamber (14) is fixedly mounted or attached to a spray gun.

12. The structure of claim 11.

13. A second return air duct (17) is additionally provided, a) the second return air duct (17) has a wall portion of the housing (10) and a duct wall portion (4') spaced apart from the wall portion, and has an inlet opening (170) located above and near the bottom portion (12); b) the return air filter (5, 5') faces the circulating air area (15), i.e. is arranged at the opening of the second return air duct (17) to the circulating air area (15) or in the second return air duct (17), c) the opening of the second return air duct (17), which accommodates the return air filter (5, 5'), can be formed as a protrusion (171) which extends the circulation air area (15) or protrudes into the circulation air area (15), or does not have a protrusion and transitions into the circulation air area (15) with an approximately straight cross section; d) the return air filter (5, 5') is in the form of a plate filter or an exchangeable filter cartridge (5') or a replaceable filter insert; e) the circulating air filter (2, 2') is in the form of a plate filter or an exchangeable filter cartridge (2') or a replaceable filter insert; f) a single return air filter (5, 5') or a series of interacting return air filters (5, 5') are provided, g) A single circulating air filter (2, 2') or a series of interacting circulating air filters (2, 2') are installed. A structure according to any one of claims 1 to 12, characterized in that

14. a) the spray nozzle (61) is directed into the second return air duct (17); b) the cleaning nozzle (69) is directed into the second return air duct (17), i.e. before the return air filter (5, 5') against the flow direction; 14. The structure of claim 13.

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