Denture cleanser and denture cleaning method

Abstract

To provide a denture cleaning agent and a denture cleaning method that collectively solve multiple problems such as dental calculi, staining, and odors, thereby mitigating the burden of cleaning dentures.SOLUTION: As a result of conducting extensive studies, the inventors have completed this invention, specifically a denture cleaning agent and a denture cleaning method that can collectively solve multiple problems including the removal of dental calculi, staining, and odors, by means of the denture cleaning agent containing a solid chlorine-based bleaching agent and an amino carboxylic acid-based chelator.SELECTED DRAWING: None

Description

[Technical Field]

[0001] The present invention relates to a denture cleanser and a method for cleaning dentures that simultaneously have multiple effects such as removal of tartar, stains, and odors. [Background technology]

[0002] Various detergent compositions are used to clean dentures. Dentures are made of various materials, such as ceramic, resin, and metal. Typical denture cleansers contain cleaning ingredients such as bleaching agents and surfactants, which can remove or reduce the visibility of stains adhering to dentures, which are the target of cleaning. However, dentures can sometimes suffer from problems such as the buildup of tartar (scale) and plaque, or odors caused by the formation of biofilms and other deposits caused by bacteria adhering to dentures.

[0003] For example, dental clinics sometimes choose to perform multiple cleaning processes using dedicated cleaners to remove tartar, stains, and odors, but repeatedly using multiple cleaners to remove various stains and odors from dentures places a burden on the cleaning staff. Also, when the stains cannot be sufficiently removed using cleaners alone, physical cleaning procedures such as brushing, scaling, and polishing must be performed, which also places a burden on the cleaning staff.

[0004] For example, Patent Document 1 describes a denture cleanser for dentures containing a gold-silver-palladium alloy in the metal portion, which contains chlorinated isocyanuric acid and / or its salts, perborate and / or percarbonate, and a benzotriazole-based compound represented by a specific chemical formula, and describes that the cleanser is expected to have the effect of effectively inhibiting rust on the metal portion of dentures due to bleaching ingredients, but is insufficient to solve multiple problems caused by various stains, such as discoloration and stains adhering to dentures, scale such as tartar, and odors.

[0005] Patent Document 2 reports a solid bleach-containing product in which bleach particles are protected by a coating layer. It is said that such a solid bleach-containing product can be stably blended with various detergent ingredients and does not cause deterioration, inactivation, or decomposition of the bleach. [Prior art documents] [Patent documents]

[0006] [Patent Document 1] Japanese Patent Application Laid-Open No. 2011-213639 [Patent Document 2] International Publication No. 2017 / 183726 Summary of the Invention [Problem to be solved by the invention]

[0007] Bacteria adhering to the surfaces of teeth and dentures in the oral cavity can grow, forming plaque. Such plaque can cause caries and periodontal disease, so it must be removed by brushing. If plaque is not removed sufficiently and remains on the denture surface for a long period of time, calcium and phosphate in saliva can deposit on the plaque, calcifying it and forming tartar. Tartar removal is widely performed at dental clinics to remove tartar buildup. However, even at dental clinics, various cleaning methods may be used, depending on the denture stain. Dental clinics may also employ physical or mechanical methods such as brushing, scaling, and polishing to remove tartar and stains from dentures, increasing the workload. Furthermore, if bacteria and other contaminants adhering to dentures are not sufficiently removed, cleaning workers may be exposed to droplets that come into contact with the dentures during cleaning, posing a risk of bacterial infection. Furthermore, bacteria adhering to dentures can cause odors, and the unpleasant odor that occurs when adjusting or cleaning dentures is also a burden for workers.

[0008] Strong acidic cleaning agents are sometimes used to remove tartar. On the other hand, chlorine bleach is sometimes used to remove stains and kill bacteria. However, mixing acidic cleaning agents with chlorine bleach generates chlorine gas, making their simultaneous use unsafe. It is also difficult to simultaneously address multiple issues, such as tartar, stains, and odors on dentures.

[0009] In response to these various problems, an object of the present invention is to provide a denture cleanser and a denture cleaning method that can reduce the burden of denture cleaning work by simultaneously solving multiple problems such as tartar, stains, and odor. Another object of the present invention is to provide a denture cleanser and a denture cleaning method that have a high cleaning effect so as to also reduce the burden of physical cleaning such as brushing, scaling, and polishing. The denture cleanser and denture cleaning method of the present invention can be used for daily denture cleaning in ordinary households, and can also be used for professional purposes such as denture maintenance in dental clinics, etc. [Means for solving the problem]

[0010] As a result of intensive research aimed at solving the above problems, the present inventors have discovered a denture cleanser and a method for cleaning dentures that can simultaneously solve multiple problems, namely, removal of tartar, stains, and odors, by using a cleanser composition containing a solid chlorine bleaching agent and an aminocarboxylic acid chelating agent. Furthermore, the denture cleanser and method for cleaning dentures that contain a solid chlorine bleaching agent and an aminocarboxylic acid chelating agent have excellent cleaning effects, and therefore can reduce the workload of cleaning workers, such as brushing, scaling, and polishing.

[0011] Furthermore, it was discovered that the detergent composition of the present invention uses a solid chlorine bleach-containing material having a coating layer as the solid chlorine bleach, thereby enabling the chlorine bleach and the aminocarboxylic acid chelating agent to be stably blended, thereby resulting in a denture cleanser that can maintain excellent cleaning effects for a long period of time. Based on these findings, the present inventors conducted further studies and have now completed the present invention.

[0012] That is, the present invention relates to the following denture cleanser and a method for cleaning dentures using the same. Item 1. Denture cleanser containing solid chlorine bleach and aminocarboxylic acid chelating agent. Item 2. The denture cleanser according to Item 1, wherein all or part of the solid chlorine bleaching agent is a solid chlorine bleaching agent-containing material having a coating layer. Item 3. The denture cleanser according to Item 2, wherein the coating layer of the solid chlorine bleach-containing product having a coating layer contains a metal salt of an aromatic carboxylic acid. Item 4. The denture cleanser according to any one of Items 1 to 3, wherein the solid chlorine bleach contains one or more selected from the group consisting of metal salts of dichloroisocyanuric acid, hydrates of metal salts of dichloroisocyanuric acid, and mixtures thereof. Item 5. The denture cleanser according to any one of Items 1 to 4, wherein the aminocarboxylic acid chelating agent is one or more selected from the group consisting of ethylenediaminetetraacetic acid, metal salts of ethylenediaminetetraacetic acid, hydrates of metal salts of ethylenediaminetetraacetic acid, and mixtures thereof. Item 6. The denture cleanser according to any one of Items 1 to 5, wherein the content ratio of the aminocarboxylic acid chelating agent to the solid chlorine bleach is 1 or more and 7 or less. Item 7. The denture cleanser according to any one of Items 1 to 6, wherein the total content of the solid chlorine bleach and the aminocarboxylic acid chelating agent is 45% by weight or more. Item 8. The denture cleanser according to any one of Items 1 to 7, wherein the pH of a 1% by weight aqueous solution of the denture cleanser is 4 or more and 8 or less. Item 9. A method for cleaning dentures, comprising the steps of: dissolving the denture cleanser according to any one of Items 1 to 8 in water to prepare an aqueous solution; and contacting the aqueous solution with dentures. Item 10. A denture cleaning method according to Item 9, wherein the concentration of the aminocarboxylic acid chelating agent contained in the aqueous solution is 1% by weight or more and 20% by weight or less. [Effects of the Invention]

[0013] The denture cleanser of the present invention contains a solid chlorine bleaching agent and an aminocarboxylic acid chelating agent, and thus has excellent effects on removing tartar, stains, and odors at the same time. Furthermore, by using a solid chlorine bleach-containing material having a coating layer on the solid chlorine bleaching agent, the solid chlorine bleaching agent and aminocarboxylic acid chelating agent in the denture cleanser are stably maintained, allowing for excellent shelf life and maintaining a high cleaning effect for a long period of time.

[0014] "The solid chlorine bleach and aminocarboxylic acid chelating agent in the denture cleanser are maintained stably" means that after the denture cleanser is stored for a certain period of time under specified conditions, the degree of deterioration due to changes over time, such as swelling or breakage, of the packaging material in which the denture cleanser is packaged is less than that of a comparison object. [Brief explanation of the drawings]

[0015] [Figure 1] 1 is a graph showing the relationship between pH and the amount of dissolved tricalcium phosphate in each aqueous solution shown in Table 1. DETAILED DESCRIPTION OF THE INVENTION

[0016] (denture cleanser) The denture cleanser of the present invention contains a solid chlorine-based bleaching agent and an aminocarboxylic acid-based chelating agent. The denture cleanser of the present invention can be suitably used to remove scale stains such as tartar, stains, odors, etc., adhering to dentures (including partial dentures and full dentures).

[0017] In the denture cleaning method of the present invention, the denture cleanser may be added to water before the denture is placed in the water, or water may be collected in advance, the denture may be placed in the water, and the denture cleanser may then be added. An ultrasonic cleaning step may also be provided. The denture cleaning method of the present invention includes the steps of dissolving the denture cleanser in water to prepare an aqueous solution, and bringing the aqueous solution into contact with the denture. If necessary, steps such as heating and stirring may also be combined. Cleaning may also be performed by spraying, wiping, or other methods using an aqueous solution containing the denture cleanser.

[0018] (Solid chlorine bleach) Examples of solid chlorine bleaching agents used in the denture cleanser of the present invention include trichloroisocyanuric acid, metal salts of dichloroisocyanuric acid, hydrates of metal salts of dichloroisocyanuric acid, dichlorohydantoin, chlorobromohydantoin, calcium hypochlorite, and crystallized sodium hypochlorite. Trichloroisocyanuric acid, metal salts of dichloroisocyanuric acid, and hydrates of metal salts of dichloroisocyanuric acid are preferred because they have excellent bleaching effects, are easy to handle, and are readily available, while sodium dichloroisocyanurate and hydrates of sodium dichloroisocyanurate are more preferred because they have excellent solubility in water. These solid chlorine bleaching agents may be used alone or in combination of two or more.

[0019] The available chlorine content (Cl2 equivalent) of solid chlorine bleach can be calculated using iodometric titration. That is, the iodine liberated by the reaction of active chlorine with potassium iodide is titrated with an aqueous sodium thiosulfate solution, and the available chlorine content is calculated using the following formula:

[0020] (Number 1) Available chlorine content (%) = a × f × 0.35452 / b (Formula 1) a: 0.1N sodium thiosulfate aqueous solution required for titration (ml) b: Sample (g) f: Factor of 0.1N sodium thiosulfate solution

[0021] The theoretical available chlorine content of trichloroisocyanuric acid is 91.5%, that of sodium dichloroisocyanurate is 64.5%, and that of sodium dichloroisocyanurate dihydrate is 55.4%.

[0022] The content of solid chlorine bleach in the denture cleanser is preferably 1% by weight or more, more preferably 5% by weight or more, even more preferably 7% by weight or more, particularly preferably 10% by weight or more, and most preferably 12% by weight or more, based on 100% by weight of the total amount of the denture cleanser, in order to achieve a certain level of available chlorine content in the denture cleanser to achieve the effects of removing stains, odors, and sterilizing or disinfecting microorganisms. Furthermore, the content of solid chlorine bleach in the denture cleanser is preferably 80% by weight or less, more preferably 50% by weight or less, and even more preferably 30% by weight or less, based on 100% by weight of the total amount of the denture cleanser, in order to enable the inclusion of compounds useful as cleaners, such as aminocarboxylic acid chelating agents and other additives, and to reduce corrosion of metal components of dentures due to excessive solid chlorine bleach.

[0023] The cleaning composition of the present invention may contain a solid oxygen bleaching agent in addition to the solid chlorine bleaching agent. Examples of solid oxygen bleaching agents include organic peroxides such as sodium percarbonate, sodium perborate, and benzoic acid peroxide, and potassium monopersulfate double salts. From the viewpoints of availability and ease of handling, sodium percarbonate and potassium monopersulfate double salts are preferred. These solid oxygen bleaching agents may be used alone or in combination.

[0024] (Solid chlorine bleach-containing material with a coating layer) The solid chlorine bleach used in the present invention is preferably a solid chlorine bleach-containing product having a coating layer. In the solid chlorine bleach-containing product having a coating layer, the solid chlorine bleach is protected by the coating layer. The compound used in the coating layer is not particularly limited as long as it can coat the solid chlorine bleach and suppress the interaction between the solid chlorine bleach and other detergent components during storage. Examples of compounds that can be used for the coating layer include metal salts of carboxylic acids, surfactants, polysaccharides, higher fatty acids, paraffin wax, zeolites, and resins. These compounds may be used alone or in combination of two or more compounds. In an embodiment where two or more compounds are used in combination, two or more compounds may be mixed to form a coating layer containing multiple compounds, or a multi-layer structure may be formed by forming a coating layer with one compound and then forming a coating layer with another compound. The coating layer may be formed so as to completely cover the solid chlorine bleach, or may be formed partially within a range that does not impair the effects of the present invention. Among the compounds that can be used for the coating layer, metal salts of carboxylic acids and surfactants are preferred because they have good solubility in water and excellent stability with solid chlorine bleach. Metal salts of carboxylic acids are more preferred because they are easy to process into a coating layer, have excellent protection properties for the solid chlorine bleach as a coating layer, and are easy to obtain and handle.

[0025] Examples of metal salts of carboxylic acids include one or more selected from the group consisting of metal salts of aromatic carboxylic acids, metal salts of acyclic dicarboxylic acids, metal salts of acyclic monocarboxylic acids, metal salts of other carboxylic acids, and mixtures thereof. Metal salts of carboxylic acids may be those in which the carboxyl group of a carboxylic acid has been completely neutralized as a metal salt, or may be those in which the carboxyl group has been partially neutralized as a metal salt, or may contain carboxylic acid that has not been converted into a metal salt. By using a metal salt of carboxylic acid, a solid chlorine bleach-containing product having a coating layer and a denture cleanser containing the same can be stabilized by protecting the solid chlorine bleach from deterioration, inactivation, and decomposition. Furthermore, the coating layer containing the metal salt of carboxylic acid is stable even when in contact with the solid chlorine bleach, and no undesirable side reactions occur between the solid chlorine bleach and the coating layer, so there is no need to provide a separate layer to isolate the solid chlorine bleach from the coating layer, and the coating layer can be provided directly on the surface of the solid chlorine bleach. In addition, the coating layer containing the metal salt of carboxylic acid is preferred because it is less likely to agglomerate and has excellent processability.

[0026] The metal salt of an aromatic carboxylic acid refers to a metal salt of a compound having an aromatic ring and a carboxyl group in its structure. The metal salt of an aromatic carboxylic acid is preferably one or more selected from the group consisting of metal salts of benzoic acid, phthalic acid (ortho-form), isophthalic acid (meta-form), terephthalic acid (para-form), trimellitic acid, and para-t-butylbenzoic acid, and mixtures thereof. Examples of the metal salt include alkali metal salts such as lithium salt, sodium salt, and potassium salt, and alkaline earth metal salts such as calcium salt and magnesium salt. Alkali metal salts are preferred from the viewpoint of availability, and sodium salts and potassium salts are more preferred from the viewpoint of solubility in water. The metal salt of an aromatic carboxylic acid is particularly preferably one or more selected from the group consisting of alkali metal salts of benzoic acid, alkali metal salts of para-t-butylbenzoic acid, and mixtures thereof. Sodium benzoate is preferred as the alkali metal salt of benzoic acid, and sodium para-t-butylbenzoate is preferred as the alkali metal salt of para-t-butylbenzoic acid.

[0027] The term "metal salt of acyclic dicarboxylic acid" refers to a metal salt of a compound having two carboxyl groups and no cyclic structure within its structure. Examples of metal salts of acyclic dicarboxylic acids include oxalic acid, malonic acid, succinic acid, fumaric acid, maleic acid, D-tartaric acid, L-tartaric acid, D-malic acid, L-malic acid, D-aspartic acid, L-aspartic acid, glutaric acid, D-glutamic acid, L-glutamic acid, itaconic acid, adipic acid, pimelic acid, suberic acid, azelaic acid, sebacic acid, undecanedioic acid, dodecanedioic acid, and tetradecanedioic acid, as well as mixtures thereof. Metal salts include, for example, alkali metal salts such as lithium salt, sodium salt, and potassium salt, and alkaline earth metal salts such as calcium salt and magnesium salt. Alkali metal salts are preferred from the viewpoint of availability, and sodium salts and potassium salts are more preferred from the viewpoint of water solubility. The metal salt of acyclic dicarboxylic acid is more preferably at least one selected from the group consisting of alkali metal salts of adipic acid, alkali metal salts of sebacic acid, alkali metal salts of undecanedioic acid, alkali metal salts of dodecanedioic acid, and mixtures thereof. Disodium adipate is suitable as the alkali metal salt of adipic acid, disodium sebacic acid is suitable as the alkali metal salt of sebacic acid, disodium undecanedioate is suitable as the alkali metal salt of undecanedioic acid, and disodium dodecanedioate is suitable as the alkali metal salt of dodecanedioic acid.

[0028] The term "metal salt of acyclic monocarboxylic acid" refers to a metal salt of a compound having one carboxyl group and no cyclic structure in its structure. Examples of metal salts of acyclic monocarboxylic acids include, for example, one or more selected from the group consisting of metal salts of formic acid, acetic acid, propionic acid, butyric acid, valeric acid, hexanoic acid (caproic acid), heptanoic acid (enanthic acid), octanoic acid, nonanoic acid, decanoic acid, dodecanoic acid, lauric acid, myristic acid, palmitic acid, stearic acid, arachidic acid, behenic acid, oleic acid, linoleic acid, linolenic acid, acrylic acid, methacrylic acid, isobutyric acid, and isovaleric acid, and mixtures thereof. Metal salts include, for example, alkali metal salts such as lithium salt, sodium salt, and potassium salt, and alkaline earth metal salts such as calcium salt and magnesium salt. Alkali metal salts are preferred from the viewpoint of availability, and sodium salts and potassium salts are more preferred from the viewpoint of solubility in water. The metal salt of acyclic monocarboxylic acid is more preferably at least one selected from the group consisting of alkali metal salts of heptanoic acid (enanthic acid), alkali metal salts of octanoic acid, alkali metal salts of nonanoic acid, alkali metal salts of decanoic acid, alkali metal salts of dodecanoic acid, alkali metal salts of lauric acid, alkali metal salts of myristic acid, alkali metal salts of palmitic acid, alkali metal salts of stearic acid, and mixtures thereof. As the alkali metal salt of heptanoic acid (enanthic acid), sodium heptanoate is preferred, as the alkali metal salt of octanoic acid, sodium octanoate is preferred, as the alkali metal salt of nonanoic acid, sodium nonanoate is preferred, as the alkali metal salt of decanoic acid, sodium decanoate is preferred, as the alkali metal salt of dodecanoic acid, sodium dodecanoate is preferred, as the alkali metal salt of lauric acid, sodium myristate is preferred, as the alkali metal salt of myristic acid, sodium palmitate is preferred, and as the alkali metal salt of stearic acid, sodium stearate is preferred.

[0029] The metal salt of other carboxylic acids refers to a metal salt of a compound that may have a cyclic structure in the compound structure and has three or more carboxyl groups. A preferred example of a metal salt of other carboxylic acids is a metal salt of citric acid. Examples of metal salts include alkali metal salts such as lithium salt, sodium salt, and potassium salt, and alkaline earth metal salts such as calcium salt. From the viewpoint of availability, alkali metal salts are preferred, and from the viewpoint of solubility in water, sodium salt and potassium salt are more preferred. Trisodium citrate is a suitable alkali metal salt of citric acid.

[0030] The metal salts of aromatic carboxylic acids, metal salts of acyclic dicarboxylic acids, metal salts of acyclic monocarboxylic acids, and metal salts of other carboxylic acids may be used alone or in combination of two or more compounds.

[0031] The content of the solid chlorine-based bleach-containing material having a coating layer in the denture cleanser is preferably 1% by weight or more, more preferably 5% by weight or more, even more preferably 7% by weight or more, particularly preferably 10% by weight or more, and most preferably 15% by weight or more, based on the total amount of denture cleanser being 100% by weight, in order to ensure that the denture cleanser has a certain level of available chlorine content to remove stains, odors, and disinfect or eliminate microorganisms. Furthermore, the content of the solid chlorine-based bleach-containing material having a coating layer in the denture cleanser is preferably 80% by weight or less, more preferably 50% by weight or less, and even more preferably 30% by weight or less, based on the total amount of denture cleanser being 100% by weight, in order to enable the inclusion of compounds useful as cleaning agents, such as aminocarboxylic acid chelating agents and other additives, and to reduce corrosion of metal components of dentures due to excessive chlorine bleach.

[0032] The content of the metal salt of carboxylic acid contained in the coating layer of a solid chlorine bleach-containing product having a coating layer is preferably 30% by weight or more, more preferably 50% by weight or more, and even more preferably 70% by weight or more, when the total amount of the coating layer is taken as 100% by weight, from the viewpoint of facilitating the formation of a coating layer on the solid chlorine bleach.

[0033] The coating layer of the solid chlorine bleach-containing product having a coating layer may contain various compounds, such as inorganic and organic compounds, as long as the effects of the present invention are not impaired. Examples of inorganic compounds include, but are not limited to, phosphates, sulfates, silicates, chlorides, iodides, and bromides. Examples of organic compounds include, but are not limited to, polysaccharides, polymeric compounds, surfactants, and salts of organic compounds.

[0034] The proportion (wt%) of the coating layer in the solid chlorine bleach-containing product having a coating layer, when the total amount of the solid chlorine bleach-containing product having a coating layer is taken as 100 wt%, is preferably 5 wt% or more, more preferably 10 wt% or more, and even more preferably 15 wt% or more, from the viewpoint of obtaining the stabilizing effect of the coating layer on the solid chlorine bleach. Also, from the viewpoint of obtaining a sufficient stabilizing effect on the solid chlorine bleach without making the proportion of the coating layer excessive, the upper limit is preferably 70 wt% or less, more preferably 50 wt% or less, and even more preferably 45 wt% or less.

[0035] In order to calculate the proportion of the coating layer in the solid chlorine bleach-containing product having the coating layer, the calculation method according to the following Equation 2 can be used.

[0036] (Number 2) Coating layer ratio (wt%) = Q1 × 100 / Q2 (Equation 2) Q1: Weight of the coating layer in the solid chlorine bleach-containing product (g) Q2: Weight of solid chlorine bleach-containing product with coating layer (g)

[0037] For example, if 1 g of a solid chlorine bleach-containing product having a coating layer contains 0.3 g of the coating layer, the proportion (wt%) of the coating layer is calculated as 0.3 × 100 / 1 = 30, or 30 wt%, according to Equation 2. The weight of the coating layer in a solid chlorine bleach-containing product having a coating layer can be determined by, for example, dissolving the solid chlorine bleach-containing product having a coating layer in a solvent such as water and analyzing the solution using a known analytical method such as liquid chromatography to quantify the weight of the compound used in the coating layer, or by subtracting the weight of the solid chlorine bleach from the weight of the solid chlorine bleach-containing product having a coating layer. The weight of the solid chlorine bleach can also be determined using a known analytical method such as liquid chromatography.

[0038] The coating layer can be identified and quantified by known methods. For example, if the absorbance of the compound used in the coating layer is known, the proportion (wt%) of the coating layer can be calculated by a method (absorbance method) in which the compound used in the coating layer is adjusted to a known concentration and a calibration curve is prepared, or the coating layer can be measured using widely known methods such as liquid chromatography and gas chromatography. If it is easier to quantify the solid chlorine bleach than the coating layer, the weight of the coating layer can be calculated from the weight of the solid chlorine bleach.

[0039] The proportion of the coating layer can be calculated from the available chlorine content of the solid chlorine bleach-containing material using the following formula 3.

[0040] (Number 3) Coating layer ratio (wt%) = (P1 - P2) x 100 / P1 (Equation 3) P1: Available chlorine content (%) of solid chlorine bleach used as raw material P2: Available chlorine content (%) of solid chlorine bleach containing coating layer

[0041] For example, if a solid chlorine bleach-containing product with a coating layer is prepared using sodium dichloroisocyanurate with an available chlorine content of 64.5% as the solid chlorine bleach, and the available chlorine content of the solid chlorine bleach-containing product with a coating layer is 40.0%, the proportion of the coating layer can be calculated as 38.0% by weight using Equation 3.

[0042] The content of the metal salt of carboxylic acid in the coating layer of a solid chlorine bleach-containing product having a coating layer may be quantified using a known analytical method such as liquid chromatography. For example, if the content of the metal salt of carboxylic acid in the solid chlorine bleach-containing product having a coating layer is 5% by weight and the proportion of the coating layer in the solid chlorine bleach-containing product having a coating layer is 30% by weight, the content of the metal salt of carboxylic acid in the coating layer is calculated to be 16.7% by weight, assuming that the total amount of the coating layer is 100% by weight.

[0043] The method for quantifying the proportion of the coating layer in a solid chlorine bleach-containing product having a coating layer and the content of the compound contained in the coating layer can be any of the above-mentioned methods or any other conventionally known methods. Even if an error occurs in the result depending on the measurement method, as long as the numerical value of the measurement result by any one method is within the specified range, the requirement can be considered to be met even if the result of the measurement by another measurement method is outside the specified range.

[0044] In addition to the solid chlorine bleach-containing material having a coating layer, the denture cleanser can further contain a solid bleach without a coating layer (sometimes simply referred to as a solid bleach) to the extent that the effects of the present invention are not impaired. The solid bleach may be a chlorine bleach or an oxygen bleach. When a solid bleach is contained, the content ratio of the solid bleach to the solid chlorine bleach-containing material having a coating layer in the denture cleanser (content of solid bleach / content of solid chlorine bleach-containing material having a coating layer) is preferably 1 or less, more preferably 0.8 or less, and even more preferably 0.5 or less. When this content ratio is 1 or less, the content of the solid chlorine bleach-containing material having a coating layer in the denture cleanser is the same as or higher than the content of the solid bleach, making it easier to obtain the effect of excellent storage stability due to the solid chlorine bleach-containing material having a coating layer and more economically advantageous than when the entire denture cleanser contains solid chlorine bleach-containing material having a coating layer.

[0045] A conventionally known manufacturing method can be used to manufacture a solid chlorine bleach-containing material having a coating layer. The manufacturing apparatus can be one or more devices selected from the group consisting of a stirring apparatus, a tumbling granulator, a fluidized bed granulator, or a combination thereof. Multiple steps can be carried out in separate processing apparatuses. From the viewpoint of ease of processing, one or more devices selected from the group consisting of a tumbling granulator, a fluidized bed granulator, or a combination thereof are preferred. The manufacturing method described in Patent Document 2 can also be used.

[0046] The solid chlorine bleach-containing material having a coating layer is preferably in the form of a powder or particles, and the average particle size is preferably 1 to 5000 μm, more preferably 10 to 3000 μm, and even more preferably 100 to 1500 μm. This average particle size can be measured using the method for measuring the average particle size of denture cleanser powders described below.

[0047] (chelating agent) The denture cleanser of the present invention contains an aminocarboxylic acid chelating agent. Examples of aminocarboxylic acid chelating agents include one or more selected from the group consisting of nitrilotriacetic acid, ethylenediaminetetraacetic acid, β-alaninediacetic acid, aspartic acid diacetic acid, methylglycine diacetic acid, iminodisuccinic acid, glutamic acid diacetic acid, serine diacetic acid, hydroxyiminodisuccinic acid, hydroxyethylethylenediaminetriacetic acid, dihydroxyethylglycine, metal salts thereof, hydrates thereof, and mixtures thereof. From the standpoints of availability, ease of handling, and tartar removal effect, sodium salts are preferred as metal salts of aminocarboxylic acid chelating agents. The sodium salt of ethylenediaminetetraacetic acid is preferred as the sodium salt. The sodium salt of ethylenediaminetetraacetic acid is more preferably one or more selected from the group consisting of tetrasodium ethylenediaminetetraacetate, disodium ethylenediaminetetraacetate, hydrates thereof, and mixtures thereof. Metal salts of ethylenediaminetetraacetic acid, such as tetrasodium ethylenediaminetetraacetate and disodium ethylenediaminetetraacetate, can be considered to be salts of ethylenediaminetetraacetic acid neutralized with an alkaline compound containing sodium ions, such as sodium hydroxide. Ethylenediaminetetraacetic acid dissociates in multiple stages when the pH of the aqueous solution is changed by adding an acid or alkali. Therefore, even if ethylenediaminetetraacetic acid, disodium ethylenediaminetetraacetate, or tetrasodium ethylenediaminetetraacetate is used, these compounds can change their dissociation state depending on the pH of the aqueous solution, and therefore can be considered to be in the same dissociation state at the same pH. Furthermore, the denture cleanser of the present invention can contain, in addition to the aminocarboxylic acid chelating agent, a phosphate chelating agent and a phosphonocarboxylic acid chelating agent. Phosphate chelating agents include one or more selected from the group consisting of tripolyphosphate, hexametaphosphate, their metal salts, their hydrates, and mixtures thereof. The phosphonocarboxylic acid chelating agent may be one or more selected from the group consisting of 1-diphosphonic acid, α-methylphosphonosuccinic acid, 2-phosphonobutane-1,2-dicarboxylic acid, metal salts thereof, hydrates thereof, and mixtures thereof.

[0048] The content of the aminocarboxylic acid chelating agent in the denture cleanser must be at least a specified amount from the perspective of tartar removal effect, and therefore, when the total amount of the denture cleanser is taken as 100% by weight, it is preferably at least 1% by weight, more preferably at least 5% by weight, even more preferably at least 10% by weight, particularly preferably at least 20% by weight, and most preferably at least 30% by weight. On the other hand, since further improvement in effect cannot be expected even if an excessive amount of aminocarboxylic acid chelating agent is contained, when the total amount of the denture cleanser is taken as 100% by weight, it is preferably at most 90% by weight, more preferably at most 85% by weight, and even more preferably at most 80% by weight.

[0049] (Ratio of aminocarboxylic acid chelating agent to solid chlorine bleach) The inventors have found that the ratio of the solid chlorine bleaching agent to the aminocarboxylic acid chelating agent contained in the denture cleanser of the present invention is preferably within a specific range from the viewpoint of simultaneously solving the problems of removing tartar, stains, and odors. The ratio of the aminocarboxylic acid chelating agent to the solid chlorine bleaching agent is calculated by dividing the content of the aminocarboxylic acid chelating agent in the denture cleanser by the content of the solid chlorine bleaching agent. If the ratio of the aminocarboxylic acid chelating agent to the solid chlorine bleaching agent is too small, the content of the solid chlorine bleaching agent will be relatively higher than the content of the aminocarboxylic acid chelating agent. Therefore, the ratio of the aminocarboxylic acid chelating agent to the solid chlorine bleaching agent is preferably 1 or more, more preferably 1.7 or more, even more preferably 2 or more, particularly preferably 3 or more, and most preferably 4 or more. On the other hand, if the ratio of the aminocarboxylic acid chelating agent to the solid chlorine bleach is too large, the content of the aminocarboxylic acid chelating agent will be relatively too high compared to the content of the solid chlorine bleach, so the ratio of the aminocarboxylic acid chelating agent to the solid chlorine bleach is preferably 7 or less, more preferably 6 or less, and even more preferably 5.7 or less. When a solid chlorine bleach-containing product having a coating layer is used as the solid chlorine bleach, the content of the solid chlorine bleach in the solid chlorine bleach-containing product having a coating layer can be used as the basis for calculation. For example, if the solid chlorine bleach-containing product having a coating layer is manufactured using sodium dichloroisocyanurate with an available chlorine content of 63.0% as the solid chlorine bleach and has an available chlorine content of 46.2%, the content of the solid chlorine bleach (sodium dichloroisocyanurate) in the solid chlorine bleach-containing product having a coating layer can be calculated as 73.3% by dividing 46.2 by 63.0 and multiplying by 100. Therefore, the content of the solid chlorine bleach (sodium dichloroisocyanurate) in a denture cleanser containing 10.0 wt% of the solid chlorine bleach-containing product having a coating layer can be calculated as 7.33 wt%. In this way, when a solid chlorine bleach-containing material having a coating layer is used in a denture cleanser, the net content of solid chlorine bleach in the denture cleanser is calculated, and then the content ratio of aminocarboxylic acid chelating agent to the solid chlorine bleach is calculated.

[0050] (Total content of solid chlorine bleach and aminocarboxylic acid chelating agent) The inventors have discovered that the total content of the solid chlorine bleaching agent and aminocarboxylic acid chelating agent contained in the denture cleanser of the present invention is preferably at least a specified value, from the viewpoint of simultaneously solving the problems of removing tartar, stains, and odors. That is, from the viewpoint of increasing the content of the solid chlorine bleaching agent and aminocarboxylic acid chelating agent, which are important active ingredients in denture cleansers, the total content of the solid chlorine bleaching agent and aminocarboxylic acid chelating agent is preferably at least 45% by weight, more preferably at least 60% by weight, and even more preferably at least 75% by weight. The total content of the solid chlorine bleach and the aminocarboxylic acid chelating agent is calculated by adding the content of the solid chlorine bleach and the content of the aminocarboxylic acid chelating agent in the denture cleanser. When the solid chlorine bleach is a solid chlorine bleach-containing material having a coating layer, the content of the solid chlorine bleach in the solid chlorine bleach-containing material having a coating layer can be used as the basis for calculation, as in the case of calculating the content ratio of the aminocarboxylic acid chelating agent to the solid chlorine bleach.

[0051] Furthermore, by setting both the content ratio of the aminocarboxylic acid chelating agent to the solid chlorine bleach and the total content of the solid chlorine bleach and the aminocarboxylic acid chelating agent within the preferred ranges, the content ratio of the solid chlorine bleach to the aminocarboxylic acid chelating agent in the denture cleanser can be maintained within the preferred range, while the contents of the solid chlorine bleach and the aminocarboxylic acid chelating agent, which are important as active ingredients, can be maintained within the preferred ranges for achieving the desired effects of the present application.

[0052] (Other ingredients) The denture cleanser of the present invention can contain a combination of various compounds that are useful for cleaning. The denture cleanser of the present invention can also contain other additives, such as alkaline compounds, surfactants, organic acids, organic acid salts, organic polymers, rust inhibitors, fragrances, colorants, enzymes, and inorganic substances, to the extent that the effects of the present invention are not impaired. Not only solid additives but also liquid additives can be used. For example, a liquid additive may be mixed in advance with a porous inorganic powder such as zeolite, and the liquid component may be supported on the inorganic substance before being added.

[0053] An alkaline compound refers to a metal salt of an inorganic or organic substance that exhibits alkalinity when dissolved in water. Examples of alkaline compounds include one or more compounds selected from the group consisting of metal silicates, metal phosphates, alkali metal hydroxides, alkaline earth metal hydroxides, metal carbonates, hydrates thereof, and mixtures thereof. The metal salt is preferably an alkali metal or alkaline earth metal salt, with alkali metal salts being preferred from the viewpoints of alkalinity, availability, and ease of handling. Among alkali metal salts, sodium salts and potassium salts are particularly preferred from the viewpoints of water solubility and availability. Two or more alkaline compounds may be combined and contained in the denture cleanser.

[0054] Examples of alkali metal hydroxides include one or more selected from the group consisting of lithium hydroxide, sodium hydroxide, potassium hydroxide, and mixtures thereof. Examples of alkaline earth metal hydroxides include one or more selected from the group consisting of beryllium hydroxide, calcium hydroxide, magnesium hydroxide, and mixtures thereof. Examples of metal carbonates include one or more selected from the group consisting of sodium carbonate (hereinafter sometimes referred to as soda ash), sodium bicarbonate (hereinafter sometimes referred to as baking soda), potassium carbonate, potassium bicarbonate, sodium sesquicarbonate, and mixtures thereof. In terms of availability and ease of handling, one or more selected from the group consisting of sodium carbonate, sodium bicarbonate, and mixtures thereof is more preferred. Examples of metal silicates include one or more selected from the group consisting of metal orthosilicates, hydrates of metal orthosilicates, metal metasilicates, hydrates of metal metasilicates, and mixtures thereof. In terms of handleability, availability, and alkaline strength, sodium metasilicate and hydrates of sodium metasilicate are more preferred. The hydrate of sodium metasilicate is preferably one or more selected from the group consisting of sodium metasilicate pentahydrate, sodium metasilicate nonahydrate, and mixtures thereof. The metal salt of phosphoric acid is preferably one or more selected from the group consisting of metal hydrogen phosphate, metal phosphate, metal pyrophosphate, metal tetrapolyphosphate, metal pentapolyphosphate, metal metaphosphate, hydrates thereof, and mixtures thereof, and more preferably one or more selected from the group consisting of sodium tripolyphosphate, sodium diphosphate, hydrates thereof, and mixtures thereof. The metal salt of phosphoric acid used as the above-mentioned phosphoric acid-based chelating agent may also be used as the alkaline compound.

[0055] The alkaline compound content in the denture cleanser is not particularly limited, but is preferably within a specified range, since excessive alkaline compound addition will relatively reduce the content of solid chlorine bleach and aminocarboxylic acid chelating agent. From the perspective of cleaning effectiveness as a denture cleanser, the content is preferably 50 wt% or less, more preferably 40 wt% or less, and even more preferably 30 wt% or less, based on the total amount of the denture cleanser being 100 wt%. Furthermore, from the perspective that a too low alkaline compound content results in insufficient pH adjustment effect, the alkaline compound content is preferably 0.1 wt% or more, more preferably 0.5 wt% or more, and even more preferably 1 wt% or more. Alkaline compounds can be used as pH adjusters to adjust the pH of denture cleanser aqueous solutions, and among alkaline compounds, carbonates such as sodium carbonate and sodium bicarbonate in particular can be used as foaming agents, since they generate carbon dioxide gas and foam when the pH of the aqueous solution is adjusted to neutral or acidic.

[0056] As the surfactant, anionic surfactants, nonionic surfactants, cationic surfactants, amphoteric surfactants, etc. can be used, but anionic surfactants are preferred from the viewpoint of ease of availability, etc. The inclusion of a surfactant makes it easier for the cleanser components to come into contact with the dentures, and the surfactant itself contributes to removing stains from the dentures.

[0057] If the surfactant content is too high, the content of other detergent components may be limited, and even if an excessive amount is added, further contribution to the cleaning effect cannot be expected. Therefore, the surfactant content in the denture cleanser is preferably 20% by weight or less, more preferably 10% by weight or less, and even more preferably 8% by weight or less, assuming the total amount of the denture cleanser to be 100% by weight. On the other hand, if the surfactant content is too low, improvement in the cleaning effect due to the surfactant cannot be expected, so it is preferably 0.1% by weight or more, more preferably 0.5% by weight or more, and even more preferably 1% by weight or more.

[0058] Alternatively, the surfactant may not be included in the denture cleanser, but may be added separately. For example, the surfactant may be added to the water into which the denture cleanser will be added, and then the denture cleanser may be added. In this case, the amount of the surfactant added separately is not particularly limited and may be, for example, in the same range as when the surfactant is included in the denture cleanser. The surfactant added separately may be one or more selected from the group consisting of anionic surfactants, nonionic surfactants, cationic surfactants, amphoteric surfactants, and mixtures thereof.

[0059] Examples of anionic surfactants include fatty acid salts such as potassium oleate soap, castor oil potassium soap, partially hydrogenated tallow fatty acid sodium soap, partially hydrogenated tallow fatty acid potassium soap; alkyl sulfate ester salts such as sodium lauryl sulfate, higher alcohol sodium sulfate, triethanolamine lauryl sulfate, and ammonium lauryl sulfate; alkyl benzene sulfonates such as sodium C12-C14 branched or linear alkyl benzene sulfonate; sulfonates such as sodium C14-C18 α-olefin sulfonate; alkyl naphthalene sulfonates such as sodium alkyl naphthalene sulfonate; and dialkyl sodium sulfosuccinate. alkyl diaryl ether sulfonates such as sodium alkyl diphenyl ether disulfonate; alkyl phosphates such as potassium alkyl phosphate; naphthalene sulfonate-formalin condensates such as the sodium salt of β-naphthalene sulfonate-formalin condensate; aromatic sulfonate-formalin condensates such as the sodium salt of aromatic sulfonate-formalin condensate; polyoxyethylene alkyl ether sulfate ester salts such as sodium polyoxyethylene lauryl ether sulfate; alkyl sulfosuccinates such as sodium alkyl sulfosuccinate; and mixtures thereof.

[0060] Examples of nonionic surfactants include alkyl ethers such as lauryl alcohol alkoxylate (e.g., lauryl alcohol ethoxylate), oleyl alcohol ethoxylate, and primary alcohol ethoxylate; polyoxyethylene alkyl ethers such as polyoxyethylene cetyl ether, polyoxyethylene stearyl ether, polyoxyethylene oleyl ether, and polyoxyethylene higher alcohol ether; EO·PO block polymers such as polyoxyethylene-polyoxypropylene block polymers, reverse-type polyoxyethylene-polyoxypropylene block polymers, polyoxyethylene-polyoxypropylene condensates, polyoxyethylene-polyoxypropylene block polymers of ethylenediamine, and reverse-type polyoxyethylene-polyoxypropylene block polymers of ethylenediamine; sorbitan fatty acid esters such as sorbitan laurate, sorbitan palmitate, sorbitan stearate, and sorbitan oleate; polyoxyethylene sorbitan laurate, polyoxyethylene sorbitan palmitate, and polyoxyethylene sorbitan polyethylene glycol fatty acid esters such as polyethylene glycol laurate, polyethylene glycol stearate, and polyethylene glycol oleate; polyoxyethylene alkylamines such as polyoxyethylene laurylamine, polyoxyethylene stearylamine, and ethylenediamine-polyoxyethylene-polyoxypropylene block polymers; alkyl alkanolamides such as lauric acid monoethanolamide, lauric acid diethanolamide, myristic acid monoethanolamide, myristic acid diethanolamide, stearic acid monoethanolamide, stearic acid diethanolamide, coconut oil fatty acid monoethanolamide, and coconut oil fatty acid diethanolamide; glycerin fatty acid esters such as stearic acid monoglyceride, stearic acid diglyceride, palmitic acid monoglyceride, palmitic acid diglyceride, oleic acid monoglyceride, and oleic acid diglyceride; sucrose fatty acid esters; and mixtures thereof.

[0061] Examples of cationic surfactants include one or more selected from the group consisting of alkylamine salts such as coconut amine acetate and stearyl amine acetate; quaternary ammonium salts such as lauryl trimethyl ammonium salt, stearyl trimethyl ammonium salt, distearyl dimethyl ammonium salt, alkyl benzyl dimethyl ammonium salt, cetyl trimethyl ammonium salt, stearyl trimethyl ammonium salt, behenyl trimethyl ammonium salt, distearyl dimethyl ammonium salt, diisotetradecyl dimethyl ammonium salt, cetyl pyridinium chloride, benzethonium chloride, benzalkonium chloride, and didecyl dimethyl ammonium chloride; and mixtures thereof.

[0062] Examples of amphoteric surfactants include alkyl betaines such as lauryl betaine, stearyl betaine, and 2-alkyl-N-carboxymethyl-N-hydroxyethyl imidazolinium betaine; amine oxides such as lauryl dimethylamine oxide; and one or more selected from the group consisting of these.

[0063] The surfactant is preferably an anionic surfactant from the viewpoints of availability and excellent blending stability with solid chlorine bleaches such as sodium dichloroisocyanurate. From the viewpoints of particularly excellent blending stability with solid chlorine bleaches and fine foam, it is more preferable to use, for example, one or more surfactants selected from the group consisting of linear alkylbenzene sodium sulfonate, sodium α-olefin sulfonate, sodium alkyl sulfate, and mixtures thereof.

[0064] The organic acid is not particularly limited, but examples thereof include one or more selected from the group consisting of oxalic acid, malonic acid, succinic acid, fumaric acid, maleic acid, D-tartaric acid, L-tartaric acid, D-malic acid, L-malic acid, D-aspartic acid, L-aspartic acid, glutaric acid, D-glutamic acid, L-glutamic acid, formic acid, acetic acid, propionic acid, butyric acid, valeric acid, hexanoic acid, heptanoic acid, octanoic acid, nonanoic acid, decanoic acid, undecanoic acid, dodecanoic acid, myristic acid, stearic acid, palmitic acid, citric acid, and mixtures thereof. At least one selected from oxalic acid, malonic acid, succinic acid, fumaric acid, maleic acid, D-tartaric acid, L-tartaric acid, D-malic acid, L-malic acid, D-aspartic acid, L-aspartic acid, glutaric acid, D-glutamic acid, L-glutamic acid, citric acid, and mixtures thereof is preferred because it is solid and easy to handle at room temperature and normal pressure, and at least one selected from succinic acid, fumaric acid, and mixtures thereof is more preferred because it has excellent blend stability with solid chlorine bleaches (hypochlorous acid generating sources) such as sodium dichloroisocyanurate.

[0065] The organic acid content in the denture cleanser is not particularly limited, but because adding an excessive amount of organic acid will relatively reduce the content of solid chlorine bleach and aminocarboxylic acid chelating agent, it is preferable that it be within a specified range. From the perspective of cleaning effectiveness as a denture cleanser, the organic acid content is preferably 50% by weight or less, more preferably 40% by weight or less, and even more preferably 30% by weight or less, assuming the total amount of the denture cleanser to be 100% by weight. Furthermore, because a too low organic acid content results in insufficient pH adjustment effect, the organic acid content is preferably 0.1% by weight or more, more preferably 0.5% by weight or more, and even more preferably 1% by weight or more.

[0066] The denture cleanser of the present invention may contain, as the organic acid salt, a metal salt of the organic acid described above, or a metal salt of the organic acid used in the coating layer of the solid chlorine-based bleach-containing product having a coating layer, or may contain an acetate salt. Examples of the metal salt include alkali metal salts such as potassium salts and sodium salts, and alkaline earth metal salts such as calcium salts and magnesium salts. Sodium salts are preferred as the metal salts of organic acids from the viewpoints of availability and ease of handling.

[0067] Examples of organic polymers include one or more selected from the group consisting of polysaccharides such as carrageenan, guar gum, locust bean gum, alginic acid, alkali metal salts of alginic acid, dextrin, xanthan gum, pectin, starch, and derivatives thereof; methylcellulose, carboxymethylcellulose, alkali metal salts of carboxymethylcellulose, ethylcellulose, hydroxypropylcellulose, hydroxyethylcellulose, other cellulose derivatives, and mixtures thereof. Alternatively, examples include synthetic polymers selected from the group consisting of polyvinyl alcohol, polyacrylamide, polyethylene glycol, polyacrylic acid, polymaleic acid, olefin-maleic anhydride copolymer, acrylic acid-maleic acid copolymer, acrylic acid-sulfonic acid copolymer, diallyldimethylammonium-acrylic acid copolymer, diallylmethylamine-maleic acid copolymer, alkali metal salts thereof, and mixtures thereof. Multiple organic polymers may also be used in combination.

[0068] Among organic polymers, polysaccharides are preferred from the viewpoint of preventing soil redeposition. Among polysaccharides, from the viewpoint of blending stability with solid chlorine bleaches, for example, one or more selected from the group consisting of carrageenan, guar gum, locust bean gum, xanthan gum, and mixtures thereof are preferred, with guar gum being more preferred. Furthermore, synthetic polymers are preferred from the viewpoint of imparting dispersibility to hardness components contained in water. Among synthetic polymers, for example, one or more selected from the group consisting of polyacrylic acid, polymaleic acid, olefin-maleic anhydride copolymer, acrylic acid-maleic acid copolymer, alkali metal salts thereof, and mixtures thereof are preferred. The synthetic polymers and alkali metal salts thereof preferably have a weight-average molecular weight of 5,000 to 200,000, more preferably 10,000 to 180,000.

[0069] The content of organic polymer in a denture cleanser is not particularly limited, but because adding an excessive amount of organic polymer will relatively reduce the content of solid chlorine bleach and aminocarboxylic acid chelating agent, it is preferable that it be within a specified range. From the perspective of cleaning effectiveness as a denture cleanser, the content is preferably 50% by weight or less, more preferably 40% by weight or less, and even more preferably 30% by weight or less, assuming the total amount of denture cleanser to be 100% by weight. Furthermore, if the organic polymer content is too low, even if it is present, the effect of preventing dirt redeposition and the dispersibility of hardness components contained in water will be insufficient. Therefore, the content is preferably 0.1% by weight or more, more preferably 0.5% by weight or more, and even more preferably 1% by weight or more.

[0070] Dentures contain metal components, and denture cleansers can contain anti-rust agents. Examples of anti-rust agents include benzotriazole, tolyltriazole, 4- or 5-carboxybenzotriazole, nitrobenzotriazole, and mercaptobenzothiazole. Benzotriazole is more preferred due to its availability and anti-rust effect.

[0071] If the content of the rust inhibitor in the denture cleanser is too high, the content of other cleanser components may be limited, and even if the content is excessive, further improvement in the rust-preventing effect cannot be expected. Therefore, the content of the rust inhibitor in the denture cleanser, when the total amount of the denture cleanser is taken as 100% by weight, is preferably 20% by weight or less, more preferably 10% by weight or less, and even more preferably 8% by weight or less. On the other hand, if the content of the rust inhibitor is too low, improvement in the rust-preventing effect cannot be expected even if the rust inhibitor is included, so it is preferably 0.1% by weight or more, more preferably 0.5% by weight or more, and even more preferably 1% by weight or more.

[0072] Examples of dyes include Scarlet G Conc, Permanent Red GY, Seika First (registered trademark) Carmine 3870, Seika First Yellow 2200, Seika First Yellow 2700(B) (all trade names, manufactured by Dainichiseika Color & Chemicals Mfg. Co., Ltd.), Acid Blue 9, Direct Yellow 12 (all trade names, manufactured by Tokyo Chemical Industry Co., Ltd.), Phthalocyanine Blue, Riboflavin (all trade names, manufactured by Fujifilm Wako Pure Chemical Industries, Ltd.), and Ultramarine Blue (all trade names, manufactured by Hayashi Pure Chemical Industries, Ltd.). These dyes may be contained alone or in combination of two or more. The content of the dye in the denture cleanser is preferably 0.1 to 5% by weight.

[0073] As the flavoring, conventionally known natural flavorings and synthetic flavorings can be used. For example, flavorings with various scents such as mint, lime, and citrus can be used. The content of the flavoring in the denture cleanser is preferably 0.1 to 8% by weight.

[0074] As the enzyme, various enzymes useful for cleaning can be used.

[0075] Examples of inorganic substances (excluding alkaline compounds) include sulfates, chlorides of alkali metals, aluminum sulfates, siloxanes, clay minerals, boron compounds, etc. When an inorganic substance (excluding alkaline compounds) is contained in a denture cleanser, the content of the inorganic substance in the denture cleanser is preferably 0.1 to 60% by weight, more preferably 1 to 40% by weight, and even more preferably 1 to 20% by weight, based on the total amount of the denture cleanser being 100% by weight, because if the content is too low the desired effect cannot be achieved, while if the content is excessive the content of the solid chlorine bleach and aminocarboxylic acid chelating agent will be limited.

[0076] Examples of sulfates include alkali metal sulfates such as sodium sulfate and potassium sulfate, and alkaline earth metal sulfates such as magnesium sulfate and calcium sulfate. Examples of alkali metal chlorides include sodium chloride and potassium chloride. Examples of aluminum sulfates include aluminum potassium sulfate (sometimes called alum). Examples of clay minerals include hectorite. Examples of boron compounds include borax, boric acid, metaboric acid, and boron oxide. Examples of siloxanes include dimethylpolysiloxane. These inorganic substances may be contained in the detergent composition either alone or in combination of two or more.

[0077] (Denture cleanser formulation) The denture cleanser of the present invention is solid and may take the form of, for example, a powder, tablet, or solid. Powder, tablet, and solid forms may also be combined. Furthermore, the powder, tablet, and solid forms may each be a composition containing multiple components, or a combination of powder, tablet, and solid forms may be used, with some of the components being powder and specific components, the same or different from the powder, being tablet or solid. The denture cleanser of the present invention is preferably in powder form, as it can be rapidly dissolved in water and exert its effect. The powder can be prepared by mixing multiple powdered ingredients containing a solid chlorine bleach (e.g., a solid chlorine bleach-containing product with a coating layer) and an aminocarboxylic acid chelating agent using a commonly known method such as a mixer. Alternatively, the mixing step can be omitted and the multiple ingredients can be directly placed in a packaging material.

[0078] As used herein, "powder" refers to a collection of particles. The shape of the particles is not particularly limited, and examples include amorphous, spherical, and spheroidal shapes. Powder also includes those obtained by secondary processing into granules, such as when fine powder is processed by a conventionally known method such as fluidized bed granulation, or when powder is compressed and molded by a conventionally known method such as a chilsonator and then pulverized. The raw material compounds may be mixed in advance and then subjected to secondary processing such as granulation, or raw materials that have already been subjected to secondary processing such as granulation may be mixed to prepare the powder.

[0079] The average particle size of the powder is preferably 1 to 5000 μm, more preferably 10 to 3000 μm, and even more preferably 100 to 1500 μm. When the average particle size is 5000 μm or less, the particles are not too large and are easy to handle and use. When the average particle size is 1 μm or more, the particles are less likely to scatter due to slight wind or static electricity during handling, making them easy to use.

[0080] The average particle size of powders can be measured as follows. Using 13 sieves and a tray with openings of 75 μm, 106 μm, 150 μm, 250 μm, 425 μm, 600 μm, 710 μm, 850 μm, 1000 μm, 1180 μm, 1400 μm, 1700 μm, and 2000 μm, stack the sieves on top of the tray with the larger openings on top. The sample is placed on top of the topmost sieve with a 2000 μm opening, and then stacked on top of the tray with the larger openings on top. The stacked sieves are placed in a sieve shaker and shaken for 10 minutes to perform sieving. The sieve shaker can be used at a frequency of 3600 rpm with an amplitude of 1 mm. The particle size distribution may be measured using the method and tools (sieves) described in JIS Z 8815 and JIS Z 8801.

[0081] The sieve shaker can be, for example, the "AS200CONTROL" manufactured by Retsch, but is not limited to this. If a sieve shaker is not available, support the stacked sieves with one hand and tap the sieve frame at a rate of approximately 120 times per minute. Occasionally, place the sieve horizontally and tap the sieve frame several times firmly. Repeat this operation to thoroughly sieve the sample. If the sample is clumped or if fine powder adheres to the inside or back of the sieve, gently loosen the sample with a brush and repeat the sieving operation. Any material that passes through the sieve mesh is considered to be under-sieved. Note that "under-sieved" refers to the test sample that has passed through the sieve mesh by the end of sieving.

[0082] If the sample contains particles with a diameter greater than 2000 μm, multiple sieves with gradually increasing mesh sizes greater than 2000 μm may be added. For example, sieves with mesh sizes of 2360 μm, 2800 μm, 3350 μm, 4000 μm, 4750 μm, 5600 μm, or larger may be added. If the sample contains a large number of particles with a diameter of 75 μm or less, multiple sieves with gradually increasing mesh sizes less than 75 μm may be added. For example, sieves with mesh sizes of 63 μm, 53 μm, 45 μm, 38 μm, or smaller may be added. Sieves with other mesh sizes may also be selected.

[0083] The weight of the particles remaining on each sieve and on the tray is measured, and the weight percentage (%) of the particles on each sieve is calculated. The weight percentage of the particles on the sieves with smaller openings is added together, starting from the tray, to calculate the total. If the opening of the first sieve where the total weight percentage is 50% or more is a μm, and the opening of the sieve one size larger than a μm is b μm, the total weight percentage from the tray to the sieve with a μm opening is c%, and the weight percentage on the sieve with a μm opening is d%, the average particle size can be calculated using the following formula 4.

[0084]

number

[0085] (pH of aqueous solution of denture cleanser) The denture cleanser of the present invention preferably has a pH within a predetermined range when dissolved in water from the viewpoints of removing stains, removing scale, and suppressing chlorine gas generation. When using a solid chlorine bleach, it is considered that an alkaline pH is advantageous for removing stains, while an acidic pH is advantageous for removing scale. Furthermore, since chlorine gas is generated when an aqueous solution of a solid chlorine bleach is acidic, it is advantageous to have a pH in the neutral to alkaline range from the viewpoint of suppressing the generation of chlorine gas. After comprehensively considering these viewpoints, the inventors have found that the lower limit of the pH of a 1 wt% aqueous solution of the denture cleanser is preferably 3 or more, more preferably 4 or more, and even more preferably 4.5 or more, and the upper limit of the pH is preferably 10 or less, more preferably 9 or less, even more preferably 8.5 or less, and particularly preferably 8 or less.

[0086] (Preferred embodiment of denture cleanser) The denture cleanser of the present invention is preferably in the form of a powder from the viewpoint of solubility in water. As the solid chlorine bleaching agent, it is preferable to use a solid chlorine bleaching agent-containing material having a coating layer. As the solid chlorine bleaching agent in the solid chlorine bleaching agent-containing material having a coating layer, sodium dichloroisocyanurate, sodium dichloroisocyanurate hydrate, and potassium dichloroisocyanurate are preferred, and sodium dichloroisocyanurate is more preferred.

[0087] As the coating layer of a solid chlorine bleach-containing product having a coating layer, a metal salt of a carboxylic acid is preferred due to its good solubility in water. Examples of the metal salt of a carboxylic acid include one or more selected from the group consisting of metal salts of aromatic carboxylic acids, alkali metal salts of acyclic dicarboxylic acids, alkali metal salts of acyclic monocarboxylic acids, and mixtures thereof. As the metal salt of a carboxylic acid, a metal salt of an aromatic carboxylic acid is particularly preferred because it is easy to process as a coating layer and is readily available. As the metal salt of an aromatic carboxylic acid, sodium benzoate and sodium para-t-butylbenzoate are suitable.

[0088] From the viewpoint of removing or inhibiting scale stains, the aminocarboxylic acid chelating agent used in the present invention is preferably one or more selected from the group consisting of ethylenediaminetetraacetic acid, metal salts of ethylenediaminetetraacetic acid, hydrates of metal salts of ethylenediaminetetraacetic acid, and mixtures thereof. The metal salt of ethylenediaminetetraacetic acid is preferably sodium salt. The sodium salt of ethylenediaminetetraacetic acid is preferably one or more selected from the group consisting of disodium ethylenediaminetetraacetate, tetrasodium ethylenediaminetetraacetate, hydrates thereof, and mixtures thereof.

[0089] (Suitable method for producing a solid chlorine bleach-containing product having a coating layer) The solid chlorine bleach-containing product having a coating layer can be manufactured by a conventionally known method. For example, the compound to be used for the coating layer is dissolved in a solvent such as water or alcohol, and the solid chlorine bleach is fluidized in a tumbling granulator or a fluidized bed granulator to form a solution, and the aqueous solution of the compound to be used for the coating layer is sprayed onto the solid chlorine bleach, thereby forming a coating layer. Other manufacturing methods may also be used.

[0090] (Suitable method for producing denture cleanser) The denture cleanser of the present invention can be produced by mixing a solid chlorine bleach-containing material having a coating layer as a solid chlorine bleach with an aminocarboxylic acid chelating agent, and may further contain other additives. The components contained in the denture cleanser may be placed in a known mixer, mixed, and then packaged in small containers such as films, pouches, or bottles. Alternatively, the components contained in the denture cleanser may be placed directly in small containers such as films, pouches, or bottles without using a mixer.

[0091] (How to clean dentures) Denture cleaning methods may involve adding the denture cleanser to water and then adding the dentures, or adding the dentures to water and then adding the denture cleanser. After adding either or both the dentures and denture cleanser, the aqueous solution may be sonicated using an ultrasonic cleaner. For example, water may be placed in a glass beaker, the denture cleanser may be added, the dentures may then be added, and the glass beaker may be placed in an ultrasonic cleaner to perform ultrasonic cleaning. While the denture cleanser of the present invention has excellent cleaning effects, even short immersion periods can be effective. Since longer immersion times result in improved cleaning results, immersion times of 1 minute or more are preferred, 5 minutes or more are more preferred, and 8 minutes or more are even more preferred. Since excessively long immersion times do not provide any significant improvement in cleaning effectiveness, immersion times of 12 hours or less are preferred, and 3 hours or less are even more preferred, from the perspective of ease of cleaning.

[0092] In order to effectively exert the effects of the denture cleanser of the present invention, it is preferable that the concentration of the aminocarboxylic acid chelating agent contained in the aqueous solution after the denture cleanser has been added be within a predetermined range. The higher the concentration of the aminocarboxylic acid chelating agent, the easier it is to achieve tartar removal effects, but adding an excessive amount does not provide any further improvement in effectiveness. From this perspective, the lower limit of the concentration of the aminocarboxylic acid chelating agent contained in the aqueous solution after the denture cleanser has been added is preferably 1% by weight or more, more preferably 3% by weight or more, and even more preferably 5% by weight or more, and the upper limit of the concentration is preferably 20% by weight or less, more preferably 15% by weight or less, and even more preferably 12% by weight or less.

[0093] (tartar) Tartar is known to be composed mostly of calcium phosphate, with other components including proteins, carbohydrates, and bacteria. For example, the explanation of "tartar" in the health terminology dictionary on the Ministry of Health, Labor, and Welfare's health information website for preventing lifestyle-related diseases, "e-Health Net" (https: / / www.e-healthnet.mhlw.go.jp / information / dictionary / teeth / yh-034.html), states that approximately 80% of tartar is calcium phosphate. Therefore, the effectiveness of tartar removal can be evaluated by measuring the ability to dissolve tricalcium phosphate, which is inherently insoluble in water, in water (tricalcium phosphate dissolution amount) using tricalcium phosphate (Ca3(PO4)2), a form of calcium phosphate. In other words, the more effective a denture cleanser is at dissolving or dispersing insoluble tricalcium phosphate in water (higher tricalcium phosphate dissolution amount), the more effective it can be in removing tartar.

[0094] (Other uses) The denture cleanser of the present invention not only has high descaling, bleaching, and deodorizing effects, but also is expected to have the effect of sterilizing and disinfecting microorganisms due to the solid chlorine bleach, and therefore can be widely used as a cleaner in a variety of applications other than denture cleansers. For example, in facilities that have a mechanism for circulating water through a circulation path with a heat exchanger, such as bath facilities such as public baths, swimming pools, circulating water for landscape use, and cooling tower treated water, problems such as the formation of biofilms by microorganisms in the circulation path, scale stains due to the precipitation of hardness components in the water over long periods of water circulation, and the generation of odors associated with water contamination can sometimes be encountered, and the denture cleanser of the present invention is expected to provide a cleaning effect. When the denture cleanser of the present invention is used as a cleaner for a circulating water circulation path, the cleanser may be added to the circulating water at any point in the circulation path to a predetermined concentration, and the aqueous solution in which the cleanser is dissolved may be circulated through the circulation path to perform cleaning. [Example]

[0095] The present invention will be specifically described below using examples and comparative examples, but the present invention is not limited to these. The raw materials and experimental equipment used in the examples and comparative examples are as follows.

[0096] [raw materials] Sodium dichloroisocyanurate: Shikoku Chemicals Corporation, product name "Neochlor 60G" (available chlorine content 63.0%) Sodium benzoate: Reagent (Fujifilm Wako Pure Chemical Industries, Ltd.) Succinic acid: Reagent (Fujifilm Wako Pure Chemical Industries, Ltd.) Sodium bicarbonate: Reagent (Fujifilm Wako Pure Chemical Industries, Ltd.) Tetrasodium ethylenediaminetetraacetate tetrahydrate: Reagent (Dojindo Laboratories) Disodium ethylenediaminetetraacetate dihydrate: Reagent (Dojindo Laboratories) Sodium hexametaphosphate: Reagent (Fujifilm Wako Pure Chemical Industries, Ltd.) Tricalcium phosphate: Reagent (Fujifilm Wako Pure Chemical Industries, Ltd.)

[0097] [Materials] [Aluminum laminate film] ·Material composition (μm) PET12 / AL7 / CPP50 [Equipment, appliances] [Gas detection tube] Gastec Gas Detector Tube No. 71 Methyl Mercaptan [Sieve shaker] Recce AS200CONTROL [Tumbling Granulator] AS ONE "DPZ-1" [pH meter] Horiba F-51 [pH electrode] Horiba Ltd. "9615S-10D" [Ultrasonic cleaner] Shibata Scientific "SU-9TH" [High frequency inductively coupled plasma optical emission spectrometer] PerkinElmer "Optima 8300 ICP-OES"

[0098] (Production of solid chlorine bleach-containing material having a coating layer) ·Solid chlorine bleach-containing product with a coating layer 1 Sodium benzoate, the compound used for the coating layer, was dissolved in water to a concentration of 30% by weight to prepare an aqueous coating solution. Powdered sodium dichloroisocyanurate was placed in a tumbling granulator and rotated while heated to 60°C. The aqueous coating solution was sprayed onto the sodium dichloroisocyanurate flowing within the tumbling granulator. The spraying was stopped when a predetermined amount of coating layer was formed, yielding solid chlorine bleach-containing product 1 with a coating layer. The available chlorine content of the dried solid chlorine bleach-containing product 1 with a coating layer was 46.2%, and the coating layer ratio was 26.7% by weight. The solid chlorine bleach-containing product with a coating layer may be used without drying, even if it still contains a small amount of moisture. The average particle size was within the range of 500 to 1000 μm.

[0099] (Manufacturing denture cleansers) Powdered denture cleansers were produced by mixing the raw materials (A) solid chlorine bleach, (B) aminocarboxylic acid chelating agent, (C) alkaline compound, and (D) organic acid in the proportions shown in Tables 2 and 4. The average particle size of the powders was measured using the method described herein. The average particle size of all of the raw material powders used in the present invention was within the range of 200 to 1000 μm.

[0100] (Tartar removal test (tricalcium phosphate dissolution test)) The tartar removal effect was evaluated by measuring the dissolution effect (tricalcium phosphate dissolution amount) of tricalcium phosphate, which is inherently difficult to dissolve in water, using tricalcium phosphate (Ca3(PO4)2), a form of calcium phosphate, the main component of tartar. 100 g of water was placed in a glass beaker, and 12.3 g of the denture cleanser described in Examples 1 to 10, 15.6 g of the denture cleanser described in Example 11, 12.8 g of the denture cleanser described in Example 12, and 15.0 g of the denture cleanser described in Example 13 were each dissolved in 100 g of water. The concentrations of Comparative Examples 1 to 5 were as described below. Subsequently, tricalcium phosphate was gradually added to the aqueous solution until residual tricalcium phosphate was visually confirmed. The glass beaker was placed in an ultrasonic cleaner and ultrasonicated for 10 minutes to confirm the presence of residual tricalcium phosphate. The aqueous solution was then filtered through a 0.45 μm filter. The calcium concentration in the filtrate was measured using an inductively coupled plasma atomic emission spectrometer. From the measurement results, the amount of dissolved tricalcium phosphate was calculated as the amount of scale dissolved in the aqueous solution.

[0101] (Stain removal test) Dentures were soaked in a 0.5% albumin aqueous solution, a tannin extract, and a 0.6% iron chloride aqueous solution, in that order, for 30 minutes each. The tannin extract was prepared by adding approximately 50 g of Japanese tea leaves, approximately 9 g of black tea leaves, and 12 g of instant coffee powder to 1.2 L of boiling ion-exchanged water. This soaking procedure was repeated 10 times, and the dentures were then dried at room temperature for at least 24 hours to prepare test specimens. The test specimens were soaked in 100 g of water at 25°C in a glass beaker. Immediately after soaking, 12.3 g of the denture cleanser described in Examples 1 to 10, 15.6 g of the denture cleanser described in Example 11, 12.8 g of the denture cleanser described in Example 12, and 15.0 g of the denture cleanser described in Example 13 were added to the glass beaker. The glass beakers were then placed in an ultrasonic cleaner and subjected to ultrasonic cleaning for 10 minutes. The concentrations of the solutions used in Comparative Examples 1 to 5 were as described below. The appearance of the test pieces after ultrasonic cleaning was visually inspected and compared with a test piece from a blank test in which ultrasonic cleaning was performed using only water without any denture cleaner. If the stains were clearly removed, it was evaluated as ◯; if some of the stains were removed but some stains remained, it was evaluated as △; if there was no difference from the test piece from the blank test, it was evaluated as ×.

[0102] (Odor removal test (deodorization test)) Approximately 1 g of resin was immersed in a 15 wt% aqueous solution of methyl mercaptan for 30 minutes, then removed and used as a test specimen. The test specimen (resin) was immersed in 100 g of water at 25°C in a glass beaker. 12.3 g of the denture cleanser described in Examples 1 to 10, 15.6 g of the denture cleanser described in Example 11, 12.8 g of the denture cleanser described in Example 12, and 15.0 g of the denture cleanser described in Example 13 were placed in the glass beaker. The glass beaker was then placed in an ultrasonic cleaner and subjected to ultrasonic cleaning for 10 minutes. The concentrations of the solutions used in Comparative Examples 1 to 5 were as described below. After cleaning, the test specimen (resin) was removed from the aqueous solution, placed in a sealed container, and allowed to stand for 10 minutes. The methyl mercaptan gas concentration in the sealed container was measured using a gas detector tube.

[0103] (Storage stability test) Each denture cleanser (12.3 to 15.6 g) with the composition listed in Table 4 was placed in an aluminum laminate film and heat-sealed to obtain a denture cleanser packaged in a bag shape. The denture cleanser was then placed in an oven set at 50°C and stored for four weeks. After four weeks, the expansion rate of the aluminum laminate film in which the denture cleanser was sealed was evaluated. The expansion rate was calculated by dividing the volume of the packaged denture cleanser after four weeks by the volume of the packaged denture cleanser before the test, assuming the volume of the packaged denture cleanser before the test to be 100%. The volume was measured by immersing the sealed package in water measured in a measuring cylinder and reading the volume of the water surface that rose. A higher expansion rate (>100%) indicates greater swelling of the packaging material.

[0104] (pH measurement) Powdered denture cleansers with the compositions shown in Tables 2 and 4 were dissolved in distilled water to a concentration of 1% by weight, and the solution was adjusted to 25°C. After stirring, approximately 50 ml of the resulting solution was used to measure the pH using a pH meter. The pH meter was calibrated immediately before the measurement using pH 4, pH 7, and pH 9 standard solutions.

[0105] (Effect of chelating agents on tartar removal (amount of dissolved tricalcium phosphate)) Aqueous solutions of 10% by weight of tetrasodium ethylenediaminetetraacetate tetrahydrate (hereinafter sometimes referred to as EDTA4Na), an aminocarboxylic acid chelating agent, and sodium hexametaphosphate, a phosphate chelating agent, were prepared and evaluated for tricalcium phosphate dissolution using the method described in the previously described calculus removal test (tricalcium phosphate dissolution test). The results are shown in Table 1 and Figure 1. The pH of each chelating agent solution was adjusted by adding succinic acid or sodium bicarbonate. EDTA4Na exhibited higher tricalcium phosphate solubility than sodium hexametaphosphate across both alkaline and acidic pH ranges. Metal salts of ethylenediaminetetraacetic acid, such as tetrasodium ethylenediaminetetraacetate, can be considered salts of ethylenediaminetetraacetic acid neutralized with alkaline compounds containing sodium ions, such as sodium hydroxide. However, when the pH of an aqueous solution of tetrasodium ethylenediaminetetraacetate is altered by adding acid or alkali, ethylenediaminetetraacetic acid dissociates in multiple stages. Therefore, it is understood that even if tetrasodium ethylenediaminetetraacetate is used, the dissociation state of ethylenediaminetetraacetic acid may vary depending on the pH.

[0106] [Table 1]

[0107] (Examples 1 to 13, Comparative Examples 1 to 5) Powdered denture cleansers (Examples 1 to 13) were prepared with the compositions shown in Tables 2 and 4. Aqueous solutions of these denture cleansers were used to conduct stain removal tests, tartar removal tests, and deodorizing tests, as well as pH measurements. Additionally, as shown in Table 3, commercially available denture cleansers (Comparative Examples 1 to 5) were used to conduct stain removal tests, tartar removal tests, and deodorizing tests. Aqueous solutions of the following concentrations were used for each test for the commercially available denture cleansers, in accordance with the instructions for use for each product. Commercial product 1: 0.017g / ml (dissolve 2.6g tablets in 150ml of water) Commercial product 2: 0.018g / ml (dissolve 2.7g tablets in 150ml of water) Commercial product 3: 0.017g / ml (dissolve 2.5g of granules in 150ml of water) Commercial product 4: 0.020g / ml (dissolve 3.0g of powder in 150ml of water for one dose) Commercial product 5: 0.020g / ml (dissolve 3.0g tablets in 150ml of water) The results are shown in Tables 2 to 4. The denture cleanser of the present invention exhibited high tartar removal, stain removal, and deodorizing effects compared to commercially available denture cleansers that did not contain either a solid chlorine bleach or an aminocarboxylic acid chelating agent.

[0108] [Table 2]

[0109] [Table 3]

[0110] [Table 4]

[0111] The commercially available denture cleansers used were as follows: Ingredient information is listed based on the ingredient label of each product, and if the product does not have an ingredient label, the ingredient information is listed based on the product's website. Commercially available product 1: Trade name "Toughdent (registered trademark)" (manufactured by Kobayashi Pharmaceutical Co., Ltd.), ingredients: foaming agent (carbonate, organic acid), oxygen bleach (persulfate, perborate), excipient, anti-tartar agent, surfactant (alpha olefin sulfonate), bleaching activator (TAED), enzyme, fragrance, rust inhibitor, pigment. Commercially available product 2: Brand name "Polident® with Enzymes" (manufactured by GlaxoSmithKline Consumer Healthcare Japan), ingredients: foaming agent (sodium bicarbonate, citric acid), bleaching / disinfecting agent (potassium persulfate, sodium percarbonate), stabilizer (sodium carbonate), lubricant (sodium benzoate, polyethylene glycol), bleaching activator (tetraacetylethylenediamine (TAED)), surfactant (sodium lauryl sulfate), binder (vinylpyrrolidone / vinyl acetate copolymer, cellulose gum), fragrance, enzyme, color. Commercially available product 3: "Dent Elac® Denture Cleanser" (manufactured by Lion Dental Materials Co., Ltd.), ingredients: oxygen-based cleaning ingredients, proteolytic enzymes. (https: / / www.lion-dent.com / dental / products / basic / erac_senjho.htm) Commercially available product 4: "Denshi Soukai" (manufactured by Wada Precision Dental Laboratory Co., Ltd.), ingredients: citric acid, malic acid, sulfamic acid. (http: / / www.labowada.co.jp / lineup / ireba_soukai.html) Commercially available product 5: "Physio® Clean Tartar Kurin Denture Cleanser" (manufactured by Nissin Co., Ltd.), ingredients: organic acid, sulfamic acid, carbonate, oxygen bleach, pigment, binder, disintegrant. (http: / / www.nissin―dental.jp / products / materials / allmaterials / kurin / index.html)

[0112] (Example 5, Examples 11 to 13: Storage Stability Test) The raw materials were mixed to obtain the denture cleansers (Examples 5, 11 to 13) at the content ratios shown in Table 4. The denture cleanser described in Example 5 was 12.3 g, the denture cleanser described in Example 11 was 15.6 g, the denture cleanser described in Example 12 was 12.8 g, and the denture cleanser described in Example 13 was 15.0 g. Each was placed in an aluminum laminate film and heat-sealed to obtain a denture cleanser packaged in a bag shape with aluminum laminate film. Examples 5 and 12, and Examples 11 and 13 each share the same aminocarboxylic acid chelating agent and alkaline compound or organic acid, and can be compared between a solid chlorine bleach-containing product with a coating layer and a solid chlorine bleach-containing product with sodium dichloroisocyanurate (without a coating layer). The solid chlorine bleach content differs between Examples 5 and 12 because the available chlorine content of the solid chlorine bleach differs depending on whether or not it has a coating layer, so the content was adjusted so that the available chlorine content as a denture cleanser would be similar.The solid chlorine bleach content differs between Examples 11 and 13 for the same reason. The packaged denture cleansers were stored at 50°C for four weeks, and the results showed that Example 5, which used a solid chlorine bleach-containing product with a coating layer, had a lower expansion rate than Example 12, which used sodium dichloroisocyanurate. Also, Example 11, which used a solid chlorine bleach-containing product with a coating layer, had a lower expansion rate than Example 13, which used sodium dichloroisocyanurate. Therefore, it was confirmed that denture cleansers using a solid chlorine bleach-containing product with a coating layer on the solid chlorine bleach have superior storage stability to denture cleansers using sodium dichloroisocyanurate (which does not have a coating layer).

[0113] From the above results, it was confirmed that the denture cleanser of the present invention is superior to the comparative example in the effects of removing tartar, stains, and odors. Furthermore, it was confirmed that the storage stability is improved by using a solid chlorine bleach containing material with a coating layer. [Industrial Applicability]

[0114] The present invention has industrial applicability because it can provide a denture composition and a denture cleaning method that have a high cleaning effect and are highly effective in removing stains, scale stains, and odors.

Claims

1. A denture cleanser containing a solid chlorine bleach and an aminocarboxylic acid chelating agent, wherein the content ratio of the aminocarboxylic acid chelating agent to the solid chlorine bleach is 1 or more and 7 or less.

2. 2. The denture cleanser according to claim 1, wherein the solid chlorine bleaching agent is a solid chlorine bleaching agent-containing material, the solid chlorine bleaching agent having a coating layer in whole or in part.

3. 3. The denture cleanser according to claim 2, wherein the coating layer of the solid chlorine bleach-containing product having a coating layer contains a metal salt of an aromatic carboxylic acid.

4. 4. The denture cleanser according to claim 3, wherein the solid chlorine bleaching agent contains one or more selected from the group consisting of metal salts of dichloroisocyanuric acid, hydrates of metal salts of dichloroisocyanuric acid, and mixtures thereof.

5. 5. The denture cleanser according to claim 1, wherein the aminocarboxylic acid chelating agent is one or more selected from the group consisting of ethylenediaminetetraacetic acid, metal salts of ethylenediaminetetraacetic acid, hydrates of metal salts of ethylenediaminetetraacetic acid, and mixtures thereof.

6. 5. The denture cleanser according to claim 1, wherein the content ratio of the aminocarboxylic acid chelating agent to the solid chlorine bleaching agent is 1 or more and 7 or less.

7. 5. The denture cleanser according to claim 1, wherein the total content of the solid chlorine bleaching agent and the aminocarboxylic acid chelating agent is 45% by weight or more.

8. 5. The denture cleanser according to claim 1, wherein the pH of a 1% by weight aqueous solution of the denture cleanser is 3 or more and 10 or less.

9. 6. The denture cleanser according to claim 5, wherein the content ratio of said aminocarboxylic acid chelating agent to said solid chlorine bleaching agent is 1 or more and 7 or less.

10. 6. The denture cleanser according to claim 5, wherein the total content of said solid chlorine bleaching agent and said aminocarboxylic acid chelating agent is 45% by weight or more.

11. 6. The denture cleanser according to claim 5, wherein the pH of a 1% by weight aqueous solution of the denture cleanser is 3 or more and 10 or less.

12. 7. The denture cleanser according to claim 6, wherein the total content of said solid chlorine bleaching agent and said aminocarboxylic acid chelating agent is 45% by weight or more.

13. 10. The denture cleanser according to claim 9, wherein the total content of said solid chlorine bleaching agent and said aminocarboxylic acid chelating agent is 45% by weight or more.

14. 14. The denture cleanser according to claim 13, wherein the pH of a 1% by weight aqueous solution of the denture cleanser is 3 or more and 10 or less.

15. A method for cleaning dentures, comprising the steps of: dissolving the denture cleanser according to any one of claims 1 to 4 in water to prepare an aqueous solution; and bringing the aqueous solution into contact with dentures.

16. 16. The method for cleaning dentures according to claim 15, wherein the concentration of the aminocarboxylic acid chelating agent contained in the aqueous solution is 1% by weight or more and 20% by weight or less.

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