Device for administering fluids

Abstract

To provide a device capable of administering a liquid medicine to an animal.SOLUTION: The present invention relates to a device for administering a fluid, comprising: a cylinder (16) which has an open dispensing end (17); a plunger (36) which can be moved between a front and a rear final position in the cylinder (16) and is connected to a plunger rod that protrudes beyond the rear cylinder (16) end opposite the open dispensing end (17) along a first direction and is guided in a receiving block (10); a non-return valve (18) which closes the open dispensing end (17); and a tensioning device which is connected to the plunger rod and is arranged in the receiving block (10).SELECTED DRAWING: Figure 4

Description

[Technical Field]

[0001] The present invention relates to a device for administering fluids, the device being, for example, a needle-free self-administered device. It may be in the form of a pre-filled syringe, which allows for the administration of liquid medication to an animal. [Background technology]

[0002] Such devices for administering fluids should be as light as possible, have a long lifespan, and It is intended that the system will be simple to install and result in low maintenance and overhead costs. Summary of the Invention [Problem to be solved by the invention]

[0003] The object of the present invention is to provide a method for administering fluids that achieves at least one of the mentioned properties. The object of the present invention is to provide an apparatus for

[0004] The invention is defined in claim 1. Advantageous refinements are defined in the dependent claims. [Means for solving the problem]

[0005] The device according to the invention for administering a fluid comprises a cylinder having an open dispensing end; a piston displaceable between a front end position and a rear end position in the A piston protruding in a first direction beyond the rear end of the cylinder and guided in a receiving block. A piston connected to the rod, a check valve (or intake valve) that closes the open dispensing end, and a piston and a tensioning device connected to the tension rod and disposed on the receiving block. In tensioning operation, when the piston is at its front end position, the piston is at its rear end position. the piston rod along the first direction until the fluid to be dispensed reaches the target fluid level. Filling the cylinder and pretensioning the piston rod towards the open dispensing end. Furthermore, the tensioning device can be configured to operate in the dispensing operation when the piston is in its rear end position. The piston rod can then be released, and the applied pretension will cause the piston to In the process, the fluid in the cylinder is dispensed. According to the invention, the cylinder, together with the check valve, is a replaceable assembly. A form of interchangeable front assembly releasably connected to the receiving block, which may also be called a solid. It could be.

[0006] The front assembly is subject to the greatest amount of wear during operation of the device for dispensing fluids (preferably liquids). The entire volume can then be replaced with a new (preferably structurally identical) front assembly, which This is then connected to the receiving block. Thus, the entire device for administering fluid Durability is greatly improved.

[0007] The replaceable assembly can be arranged at the front end of the device according to the invention, in particular, e.g. During proper use of the device according to the invention, the replaceable part of the assembly is adapted to administer the fluid. In this respect, at least one of the replaceable assemblies can be in contact with the animal for which it is intended. This part protrudes from the rest of the device according to the invention. For this reason, for example, The replaceable assembly may also be referred to as a replaceable front assembly.

[0008] A replaceable front assembly is used herein to mean, in particular, a front assembly that can be replaced entirely from a receiving block. It is placed by a structurally identical front assembly that is separated and connected to a receiving block for replacement. However, the front part separated from the receiving block is understood to mean that the Maintain the assembly (e.g., by replacing worn parts such as seals) and then It is also possible to connect it back to the receptor block.

[0009] The front assembly is completely separated from the receiving block and can then be maintained or replaced. This allows for reliable avoidance of unwanted contamination. The subassembly is positioned so that it cannot be separated from the rest of the administration device without being destroyed. If you replace only the O-ring seals individually, which wear out first in the front assembly, the This makes it more difficult and increases costs.

[0010] The releasable connection between the front assembly and the receiving block may in particular be a screw connection. However, any other type of releasable connection is also possible, such as for example a bayonet connection.

[0011] The dispensing device according to the invention may have a nozzle for dispensing fluid without a needle. The nozzle is connected to the open dispensing end of the cylinder through a check valve and is part of the front assembly. Therefore, the nozzle can be replaced at the same time as the front assembly is replaced.

[0012] Alternatively, the device may be connected to the open dispensing end of the cylinder via a check valve and the front assembly The needle and cannula may be part of the may be interchangeable for some of the

[0013] The dosing device according to the invention has exactly one piston rod and exactly one front assembly. However, the dosing device may have exactly one cylinder with the same Two or more piston rods and two or more front assemblies are designed to It is also possible to have multiple cylinders, so that two or more of the same or different fluids can be injected simultaneously. The individual cylinders can have the same or different volumes.

[0014] The dispensing device according to the invention is particularly adapted to use a tensioning action to apply a fluid to be dispensed (e.g. It is in the form of a self-filling dosing device that allows the cylinder to be filled with the liquid to be administered. .

[0015] This can be achieved, for example, in such a way that the filling of the cylinder already takes place during the entire tensioning operation. Alternatively, the dosing device may be configured such that negative pressure builds up in the cylinder during the tensioning operation. Then, when the piston is at its rear end position, the negative pressure is used to For this purpose, the pump can be designed so that the fluid is drawn into the pump. The distal end of the piston may have a blind hole extending longitudinally of the piston rod. One or more radial bores branch off from this blind hole. The rear end position of the stone creates a fluid connection to a reservoir of fluid to be administered.

[0016] The dosing device according to the invention may comprise a motor used to perform the tensioning action. The motor provides the energy required to build up pretension in the piston rod. The motor may in particular be mounted on a receiving block.

[0017] To operate the motor and possible additional equipment, an energy source is provided, e.g. For example, the energy source may be a battery and / or a storage battery. The energy source can be formed as the base of the administration device. It can be mounted or fixed.

[0018] The tensioning device tensions the piston rod toward the open dispensing end when the piston is in the rearward position. The device may have a spring that pretensions the device.

[0019] The dosing device according to the invention is rotatable by a motor and extends along a helical line. The slope may further include a slope having a slope path extending from a first slope along the slope region. can rise from one plateau or level to a second plateau or level , and can descend from the second plateau to the first plateau via the transition side. Thus, the ramp can be called a spiral with a single turn and a step. .

[0020] The tensioning device is a roller that contacts the slope and has a piston that protrudes out of the cylinder. a roller rotatably mounted on a driver connected to the end of the rod; Therefore, when the slope rotates, the slope runs under the rollers, The roller rotates. The roller has its rotation axis perpendicular to the first direction (or the piston Preferably, the head is mounted so that the axis of the head is perpendicular to the longitudinal axis of the head.

[0021] In tensioning operation, the ramp that starts when the roller contacts the first plateau is The roller travels on the sloped region to a second plateau, which causes the piston to reach its rear end position. In the dispensing operation, the roller contacts the second plateau. The ramp starts with the roller passing through the transition side and then reaches the first plateau. This allows the piston to rotate until it moves to its forward end position.

[0022] The distance of the second plateau from the first plateau along the axis of rotation of the inclined plane is preferably The distance from the front end position to the rear end position of the piston along the direction of Corresponds to Roke.

[0023] Therefore, the rotational motion of the motor is transferred by the ramps and rollers to the longitudinal axis of the piston rod. The motor then applies tension to the dosing device, which is then converted into a translational movement along the axial direction. This allows the user to control the triggering element, e.g., a push button, switch, or lock. Simply actuate the switch or button to release the dispense action and thus dispense the fluid. In this way, for example, it is possible to rapidly inject a drug into many animals in succession.

[0024] The sloped area of ​​the sloped road includes a first portion adjacent to the first plateau and a second portion adjacent to the first plateau. wherein the slope of the second portion is greater than the slope of the first portion.

[0025] Advantageously, therefore, at the start of the tensioning operation, the ramp has a relatively small slope, The result is that the motor needs to apply less force or torque. This is advantageous during starting of the motor, as more current is used during starting. As soon as the first part joins the second part, the starting problem mentioned above is overcome, so Larger inclinations can now be easily achieved, which improves the durability of the motor. To rise.

[0026] The slope of the ramp should be designed so that both sections are linear with respect to the angle of rotation of the screw. However, if the first part and / or the second part are nonlinear with respect to the rotation angle, It is also possible to have a file, in which case the slope of each part is the average slope of the parts. Preferably, the nonlinear profile of each section has a local slope as the rotation angle increases. A non-linear profile of each part is preferred. It may be a concave curved profile.

[0027] In particular, the rotation angle area (or rotation angle length) of the first part is larger than the rotation angle area ( The rotation angle area of ​​the first part and the rotation angle length of the second part can be smaller than the rotation angle area of ​​the first part. The ratio of the rotation angle area of ​​the part is preferably less than or equal to 4 / 6 and greater than or equal to 1 / 9.

[0028] In the case of the dosing device according to the invention, the roller has a support area that rests on the inclined area of ​​the ramp and a support At least one side wall having an outer diameter smaller than the outer diameter of the sloped area and not resting on the sloped area of ​​the ramp. During a dispensing operation, the support region and the side region may be adjacent to each other. Both of these can contact the edge of the slope, which then forms the second plateau on the transition side. This is because in the area of ​​the slope, the rolling resistance or friction between the roller and the slope This provides the advantage of a relatively low resistance. Both the upper and side areas then rest on the edges, so that the support surface is now enlarged and present This is because the greatest force acts on the roller during its transition through the edge. , and therefore advantageously reduces unwanted pressure peaks. Thus, the durability of the roller is improved.

[0029] In particular, the roller has an outer diameter on either side of the support area that is smaller than the outer diameter of the support area. This allows for a smooth transition through the edges. The pressure on the roller is further reduced.

[0030] The rollers can be designed so that the outer diameter of the support area is constant. The diameter increases in the direction toward the side of the roller (or away from the support area or may decrease (as the distance from the area increases).

[0031] The rollers may be in the form of plastic rollers. The ramps may be constructed from metal.

[0032] In the case of the administration device according to the invention, the receiving block is a one-piece receiving block manufactured by additive manufacturing. The endothelial cell may be in the form of a tubular block.

[0033] Such additive manufacturing methods may also be called 3D printing, and are, for example, laser sintering methods. could be.

[0034] This allows for the production of a receiving block that is relatively light in weight and has high stiffness and strength. The total weight of the dosing device is therefore kept as low as possible, making it convenient for the user. This makes the operation comfortable and durable.

[0035] Furthermore, the integrated formation of the receiving block by additive manufacturing allows the receiving block to be made extremely small. This advantageously allows for the creation of features that are not possible with conventional machining manufacturing methods.

[0036] The material used for the receiving block is preferably a metal (or metal alloy), in particular titanium. Therefore, the receiving block is made of a metal (or metal alloy), in particular titanium. Furthermore, the material of the receiving block may be aluminum, steel (e.g., maraging steel), ), stainless steel, titanium, nickel alloys and / or cobalt chromium alloys Further possible materials are AlSiMg alloys, CoCrMo alloys and nickel. Furthermore, weldable materials can be used. These materials are In both cases, a receiving block is produced from them by additive manufacturing (particularly by laser sintering). It may be in a form such that it can be manufactured (for example, as a powder).

[0037] The receiving block contains the motor bearing, the guide cylinder for the piston rod, and the small At least one receptacle, a receptacle for fluid connection of a fluid container, and / or at least The housing may also have one or more fixing points, which are integrally formed with the receiving block. do.

[0038] The piston may be integrally formed with the piston rod. The front end of the cylinder forms the piston. However, the piston is connected to a separate piston rod. It is also possible that the element

[0039] It goes without saying that the above features and those not yet described below are not necessarily part of the described composition. may be used in combination with other components or by themselves without departing from the scope of the present invention. It is available.

[0040] The present invention will now be described in detail with reference to the accompanying drawings, which likewise disclose the essential features of the invention. These exemplary embodiments are merely examples. These are illustrative and should be construed as limiting. A description of an exemplary embodiment having an element or component may include all of the elements or components. This should not be construed as meaning that all of the above are required for implementation purposes. Alternative embodiments may also include alternative elements and components, fewer elements or components, or may include additional elements or components. Elements or components of the embodiments may be combined with one another. The modifications and variations described for one may also be applied to the other exemplary embodiments. To avoid repetition, identical or mutually corresponding elements in the various figures are designated by the same reference numerals. are shown and not repeated. [Brief explanation of the drawings]

[0041] [Figure 1] 1 shows a perspective view of an exemplary embodiment of a dosing device 1 according to the invention. [Figure 2] 2 shows a schematic cross-sectional view of the administration device 1 of FIG. 1. [Figure 3] A schematic enlarged cross-sectional view of the first front assembly 13 is shown. [Figure 4] A schematic cross-sectional view of the first front assembly 13 and the distal end 30 of the receiving block 10 is shown when not connected to each other. [Figure 5] 1 shows a schematic cross-sectional view of the first front assembly 13 screwed onto the distal end of the receiving block 10, with the piston 36 in its rearmost position. [Figure 6]A cross-sectional view according to FIG. 5 is shown, where, for a dosing operation, the piston 36 is in its forward end position and the trigger cage 21 is in its release position. [Figure 7] 1 shows a perspective view of the receiving block 10 together with the tensioning device S, which is in its basic position with the piston 36 in its front end position. [Figure 8] 7 shows a perspective view of the receiving block 10 together with the tensioning device S according to FIG. 7, where the tensioning device S is in its tensioning position with the piston 36 in its rear end position. [Figure 9] 8 shows a cross-sectional view of a receiving block 10 together with a tensioning device S according to FIG. [Figure 10] 1 shows an enlarged perspective detail view of the rear part of the tensioning device S with roller 51 and bevel 52 of a variant of the dosing device 1 according to the invention with only one cylinder-piston arrangement. [Figure 11A] A diagram showing the profile of the ramp 53 is shown, where the angle of rotation is plotted along the x-axis and the stroke along the longitudinal axis of the piston rod 36 is plotted along the y-axis. [Figure 11B] A diagram showing the modified profile of the ramp 53 is shown, where the rotation angle is plotted along the x-axis and the stroke along the longitudinal axis of the piston rod 36 is plotted along the y-axis. [Figure 12] A perspective view of the roller 51 is shown. [Figure 13] A top view of the roller 51 is shown. [Figure 14] A perspective view of the receiving block 10 is shown. [Figure 15] A perspective view of the receiving block 10 is shown. [Figure 16] A top view of the receiving block 10 is shown. [Figure 17] A cross-sectional view of the receiving block 10 is shown. DETAILED DESCRIPTION OF THE INVENTION

[0042] In an exemplary embodiment shown in FIG. 1, a device according to the present invention for dispensing a fluid (e.g., a liquid) is provided. The device 1 comprises a housing 2 with a base 3, which may also be in the form of a standing base 3, and a holder 4 for holding the device 1. a gripping portion 4 for holding the device; a trigger 5 disposed on the gripping portion 4 for actuating the device 1; It comprises a head region 6 having a dispensing region 7 and a receiving portion 8 at the upper end of the head region 6 .

[0043] In the exemplary embodiment described herein, a dispensing device according to the present invention, which may also be referred to as a dispensing device 1, is provided. The device 1 is designed to simultaneously administer two different drugs to an animal, and the administration of the drugs is performed by needles. The procedure is performed through the skin without the use of a needle.

[0044] In the case of the administration device 1 according to the invention, as will be explained in more detail below, a separate drug is administered for each drug. In each case, a cylinder-piston arrangement is provided, , the fluid is injected by moving the piston towards the dispensing end, and the fluid is injected by moving the piston in the opposite direction. a self-filling device in which the cylinder is filled for the next injection operation by moving It is a type of form.

[0045] As can be gathered from the schematic cross-sectional view of the administration device 1 in FIG. A receiving block 10 supporting a base plate 11 and a motor 12, and two front assemblies 13, 14 In the view of FIG. 2, only the front assembly 13 of the two front assemblies 13 and 14 is visible. Since the front assemblies 13 and 14 are identically constructed, the front assembly 13 is essentially The medication container M containing the liquid medication for the front assembly 13 is This is shown diagrammatically in section 8.

[0046] A cross-sectional view of the front assembly 13 is shown in Figure 3. The front assembly 13 is a dispenser with an open dispensing end 17. The ejector cylinder 16 is formed in an insert 15. A check valve 18 (or intake valve 18) ) is located on the outlet side of the open dispensing end 17. When the check valve 18 is opened, the open dispensing end 17 is connected to a nozzle 18 through which the fluid to be dispensed (here, the corresponding liquid drug) is dispensed. It makes sense.

[0047] The check valve 18 is pretensioned towards the open dispensing end 17 via a spring 20 to prevent the check valve Valve 18 closes open dispensing end 17 with check valve 18 in the position shown in FIG.

[0048] Additionally, the front assembly 13 extends over the nozzle 19 and is secured to the open dispensing end 1 by a spring 22. 7 toward the nozzle 19, and a trigger cage 21 to which pretension is applied. The trigger cage 21 is displaced along the longitudinal axis of the front assembly 13 (from left to right in FIG. 3). When the administration device 1 is placed on the corresponding skin site of an animal, The trigger cage is positioned in a direction from the nozzle 19 towards the open dispensing end 17, and in the process For example, a contact sensor (not shown) may be triggered, as will be described in more detail below. , allowing the triggering of the dosing action.

[0049] The insert 15 is inserted into the proximal end 24 of the syringe cylinder 16 opposite the open dispensing end 17. The nozzle has radially extending supply channels 25 through which the fluid to be administered or or liquid medication enters the syringe cylinder 16 for the next injection action.

[0050] The proximal end 26 of the front assembly 13 is formed with an external thread 27 and has a guide bushing 28 disposed therein. , and therefore the distal end 30 is provided with an internal thread 31 for mating with the external thread 27 of the front assembly 13. 4, so that the front assembly 13 can be threaded onto the distal end 30 (FIG. 4) of the receiving block 10. Figure 4 shows the front assembly 13 and the distal end 30 of the receiver block 10 prior to the screwing operation. In FIG. 5, the two elements 13, 30 are screwed together, so that the receiving block 10 is The piston rod 35 is inserted into the syringe shaft together with the piston 36 formed at its distal end. The piston rod 35 protrudes slightly into the cylinder 16 and is guided through the guide bush 28. As will be explained in detail below, the piston rod 35 can be moved from the basic position shown in FIG. 6 in a direction toward the open dispensing end 17. From this position, the robot can return to the basic position shown in FIG.

[0051] When the piston rod 35 is in its distal end, which is its base position, the piston 36 is When the piston rod 35 is in the dispensing position, the piston 36 It is in the end position (Figure 6).

[0052] When the piston rod 35 is in the basic position shown in FIG. 5, the syringe cylinder 16 The piston rod 35 is then inserted into the open dispensing end 17. When the drug is moved toward the skin, the check valve 18 opens, thus allowing the drug to be injected into the skin through the incision. through the nozzle 19 as a jet that cuts into the skin of the animal to the extent that it can be applied. The liquid is dispensed.

[0053] Backward movement (movement along the first direction) from the dispensing position shown in FIG. 6 to the base position shown in FIG. 5 During this time, the check valve 18 closes, creating a negative pressure in the syringe cylinder 16, which then The further the piston rod 35 is from the open dispensing end 17, the larger it becomes. Once in this position, at least one of the syringe cylinder 16 and the supply channel 25 To achieve this fluid connection, the distal end of the piston 36 A blind hole 37 is formed in the inner wall of ... , the end thereof pointing away from the blind bore 37 leads to one of the supply channels 25. At least one transverse bore 38 is formed through the grooves 34. As shown only in FIG. A supply channel 25 for the components is provided between the insert 15 and the distal end 30 of the receiving block 10. and communicates with a chamber 32 which is formed in the chamber 32 and is connected to the drug container M via a connecting element 33. The negative pressure present in the syringe cylinder 16 causes the drug container M to be drawn through the connecting element 33 and the channel. the bar 32, one or more feed channels 25, the transverse bore(s) 38 and the Through the lined bore 37, the liquid medication is drawn into the syringe cylinder 16, resulting in an injection. The ejector cylinder 16 is filled with the liquid drug, thus releasing the drug during the next trigger stroke. It can be administered again, where the movement of the piston rod 35 from the base position to the injection position At the start of the This allows the piston 36 or piston rod 35 to be accelerated more easily. This creates a high pressure that acts on the remainder of the medication in the syringe cylinder 16, This push back is advantageous as this is desirable for needleless injections as described above.

[0054] In particular, the front assembly 13, which includes the syringe cylinder 16, check valve 18 and nozzle 19, The front assembly 13 is designed to be replaceable as a whole. and threaded into a corresponding internal thread 31 formed in the distal end 30 of the receiving block 10. The front assembly 13 is subject to wear during operation of the dispensing device 1 and can be removed again from the internal thread 31. Therefore, a worn front assembly 13 can be easily replaced with a new, structurally identical front assembly 13. This allows for easy removal of the components of the administration device 1 that are most susceptible to wear. Advantageously, the administration device 1 as a whole can be used for a longer period of time, since the You will be able to do this.

[0055] The front assembly 13 is completely replaceable, ensuring that unwanted contamination is avoided. This undesirable contamination can occur, for example, when the first The O-ring seals, which wear out over time, are fixed and non-replaceable to the rest of the device known in the art. If the cylinders are replaced separately in the area where they are connected to the This increases costs.

[0056] As best seen in FIGS. 7-9, the receiving block 10 is a first front assembly 13 The first receiving cylinder 40 in which the piston rod 35 is guided and the piston of the second front assembly 14 and a second receiving cylinder 140 in which the stone rod 135 is guided. - the piston configuration and therefore the configuration of the two receiving cylinders 40, 140 are identical In the description of the receiving block 10, essentially a first cylinder having a first receiving cylinder 40 is shown. Only the inner piston configuration is described below. The elements of the first receiving cylinder 40 are designated by reference numerals which are 100 higher than those of the elements of the first receiving cylinder 40. are shown in the figure but will not be explained again.

[0057] The piston rod 35 moves from a tensioned base position shown in FIG. 5 to an injection position shown in FIG. A first receiving cylinder 40 containing a spring 41 for moving the piston rod 35 is provided. The distal end 42 of the spring 41 abuts against a stop 43 of the piston rod 35. As shown in FIG. 9, the proximal end 44 of the spring 41 is connected to the proximal end of the first receiving cylinder 40. Since the screwed guide bush 45 is in contact with the injection position shown in FIG. While the piston rod moves along the spring 41 is compressed and thereby pretensioned.

[0058] As can be seen particularly from the enlarged perspective view of FIG. 10, the proximal end of the receiving cylinder 40 The end of the piston rod 35 that projects outwards has a rotatably mounted roller 51. The roller 51 is connected to a driver 50 which rotates the piston rod 35. It extends substantially perpendicular to the manual axis.

[0059] The perspective view of Figure 10 shows a variant of the administration device 1 according to the invention. In this variant, a single Only the cylinder-piston arrangement is formed, and the driver 50 is connected to the proximal end of the piston rod 35. and the proximal end of a guide rod 39 displaceably mounted on the receiving block 10. can be.

[0060] The roller 51 rotates under the roller 51 and is driven by the motor 12 to rotate the piston rod 3 The vehicle runs on a ramp 52 that rotates around an axis parallel to the longitudinal axis of the vehicle. Batteries and / or accumulators are provided to supply current to the motor. can be arranged, for example, in the base 3 or as the base 3 of the administration device 1.

[0061] The slope 52 is a spiral, as can be seen from Figures 7, 8 and 10 in particular. It has a slope road 53 that runs in a single turn along the line.

[0062] In FIG. 11A, the rotation angle α is determined with respect to the pitch difference z parallel to the longitudinal direction of the piston rod 35. At the rotation angle α0 = 0°, the minimum pitch height z0 exists, and the piston The starting point is when the ramp 52 is at its front end position. 3 runs under the roller 51, and the rotational movement of the slope 53 moves the piston rod 35 in the longitudinal direction. along the axis, which is converted into a translational movement of the roller 51 together with the driver 50, resulting in a piston 5. The injection rod 35 moves from its injection position shown in FIG. 6 to its home position shown in FIG.

[0063] For this purpose, the unwound ramp 53 according to FIG. 11A is rotated from the angle of rotation α0 to the angle of rotation α1. First plateau (slope = 0 or slightly greater than or slightly less than zero) up to α1 The slope 53 is formed from a turning angle α1 to a turning angle α2. At a rotation angle α2 (and corresponding pitch height z1), The pitch has a slope greater than that of the first linear slope portion S1 (between the rotation angles α1 and α2). The second slope exists up to a rotation angle α3, and then If the rotation angle α4 is less than 360°, the pitch height z2 will not increase even if the rotation angle is further increased. No (or only a slight increase or a slight decrease) merges into a second plateau do.

[0064] At a rotation angle α5, the transition side 46 connecting the second plateau to the first plateau creates an edge A portion 54 is formed.

[0065] In the region from α3 to α4, the piston rod 35 is in its tensioned state according to FIG. In the basic position, the administration device 1 is therefore ready to administer a liquid medication.

[0066] Then, when the trigger 5 is actuated and the trigger cage 21 is in the trigger position, the motor 12 causes the inclined surface 52 to rotate further, so that the rotation angle α5 is exceeded, and the roller 51 4, and the tension of the spring 41 causes the pitch height z2 to be reduced to the pitch of the first plateau. The fluid in the syringe cylinder 16 drops sharply to a height z0 as described above. It is injected.

[0067] Motor 12 then further rotates ramp 52 to a second plateau where rotational motion The syringe cylinder 16 is then stopped, allowing the syringe cylinder 16 to be refilled with the liquid medication and the piston The tension rod 35 is returned to its tensioned base position. This allows the dosing device 1 to be repeatedly wound up and It can be triggered.

[0068] The two sloped sections S1 and S2 are sloped regions running from the first plateau to the second plateau. The two inclined portions S1 and S2 do not need to run linearly with respect to the rotation angle. They can also have a concave curvature (concave curve), as shown by way of example in FIG. 11B. (In the case of a curve, the local tilt increases as the rotation angle increases.) However, even in this case, The average slope of the first slope portion S1 is smaller than the average slope of the second slope portion S2.

[0069] A motor 12, a ramp 52, a driver 50 having a roller 51, and springs 41, 141. The combination of the guide bushes 45, 145 can be called a tensioning device S.

[0070] As can be seen from Figures 12 and 13, the roller 51 has a constant outer diameter. The central region 55 has a diameter of 1 / 2 mm, and is flanked by side regions 56 having a diameter that decreases toward the sides. Areas 56 and 57 are adjacent.

[0071] The two side regions 56 and 57 are each rounded so that the roller 51 has no edges. Upon rotation of the ramp 52, the central region 55 is adjacent to the ramped end regions 58, 59. In the rotation angle range from α0 to α3 (especially from α0 to α5), the road is on a slope 53, whereas in the side area Regions 56 and 57 are not in the rotation angle region, but rather are in the region of the rotation angle when traveling beyond edge 54. Only the roller 51 contacts the ramp 53. Thus, the roller 51 during tensioning of the piston rod 35 The rolling resistance (the rotation of the slope from the first plateau to the second plateau) should be as low as possible. The second or upper plateau of the ramp 53 (the rotation angle region α3 to α4 ) to the lower plateau (rotation angle region α1 to α2), side regions 56 and 57 51 also contacts the edge 54 of the ramp 52. The force is advantageously distributed over a larger support surface (central region 55 and two side regions 56, 57). This reduces the resistance of the device 1, and in particular the rollers 51. Durability is improved.

[0072] The slope characteristics of the ramp 53 described in connection with FIGS. 11A and 11B are The tilt angle range α1 to α2 has a small slope and therefore needs to be provided by the motor 50. This is advantageous because less torque is required in this region. Since the motor 50 always draws a relatively large amount of current, it is difficult to accurately measure the current during the start-up of the motor 50 from the first plateau. When the pitch height z1 is reached, the relatively high rotation angle range from α2 to α3 is reached. The tilt can be easily overcome by the motor 50.

[0073] These characteristics of the slope of the ramp 52 advantageously improve the durability of the motor 50 .

[0074] As can best be seen from the diagrams of FIGS. 14 to 17, the receiving block 10 As used herein, for example, laser sintering, selective laser sintering or direct metal sintering are used. Additive manufacturing methods such as metal laser sintering are used, which allow for finer and more precise manufacturing than mechanical machining methods. In this way, relatively light receiving blocks can be fabricated. A closure 10 can be provided to ensure that the administration device 1 is highly durable.

[0075] Examples of materials that can be used for the receiving block 10 include aluminum, steel (e.g., maraging steel), and Examples include: steel, stainless steel, titanium, nickel alloys and / or cobalt chromium alloys. Herein, the material for laser sintering is preferably in the form of a metal powder. Additive manufacturing or layer-by-layer manufacturing of the receiver block 10 involves depositing thin layers of powder material onto the build platform. The laser beam can be applied to the computer-generated image of the receiving block 10. The powder is precisely melted at points predetermined by the part design data. The foam is lowered and an additional thin layer of powder material is applied. The material melts again and forms a defined These steps are repeated until the entire receptor block 10 is formed. Repeat.

[0076] In addition to the previously mentioned receiving cylinders 40, 140, the receiving block 10 has four substrate receiving points. 60, 61, 62 and 63, on which the substrate 11 is placed, e.g., a receiving block It can be screwed onto 10.

[0077] Additionally, the receiving block includes a motor bearing 64 for receiving and mounting the motor 12. can.

[0078] Furthermore, four fixing points 65, 66, 67 and 68 are attached to the outer housing 2 of the administration device 1. Corresponding receiving portions 265, 266, 267 of the outer housing 2 and Portions of 268 are shown in FIGS.

[0079] The distal end of the receiving block 10 is provided with an umbrella-shaped dispensing area 7, which is 2. In addition to the corresponding internal threads 31 and 131 for the front assemblies 13 and 14, the trigger cable Receptacles 69 and 121 for respective trigger sensors (not shown) for detecting the positions of the pages 21 and 121. It has 69.

[0080] Further, an O-ring receiving portion 70 (for example, FIG. 9, FIG. 16 and 17) are formed in the dispensing area 7, and in the installed state, the adjacent housing 2 Ensure a tight seal against

[0081] Furthermore, the receiving block 10 for each receiving cylinder 40, 140 is also called a fluid adapter. and a receiving portion 72, 172 into which a corresponding connecting element 33, 133 can be inserted. do.

[0082] The connecting elements 33, 133 are preferably manufactured by machining.

[0083] Titanium is preferably used as the material for the receiving block 10. This material is Firstly, it is relatively light, and secondly, it has the required strength. Any other material may be used.

[0084] The above explanation is based on the idea of ​​administering two different drugs simultaneously, except The dosing device 1 according to the invention is such that the receiving block 10 only has one individual receiving cylinder 40. and thus administering only a single drug during triggering. Then, the second receiving cylinder 140 and the second cylinder-piston rod It is preferable that the combination of the codes be omitted.

[0085] The exemplary embodiment described above is based on an administration device 1 in the form of a needle-free administration device 1. However, this may also be in the form of an administration device 1 with a needle or cannula. Well, in this case, the needle or cannula is intended to penetrate the skin of the animal. and then administration of the liquid drug is carried out in the manner described.

Claims

1. a cylinder (16, 116) having an open dispensing end (17); a piston (36) displaceable in said cylinder (16, 116) between a front end position and a rear end position, said piston (36) projecting in a first direction beyond the rear end of said cylinder (16, 116) opposite said open dispensing end (17) and connected to a piston rod (35, 135) guided in a receiving block (10); a check valve (18) closing the open dispensing end (17); a tensioning device (S) connected to the piston rod (35, 135) and arranged on the receiving block (10); 1. A device for administering a fluid, comprising: wherein the tensioning operation of the tensioning device (S) is such that, when the piston (36) is in the front end position, the tensioning device (S) moves the piston rod (35, 135) along the first direction until the piston (36) is in the rear end position, thereby filling the cylinder (16, 116) with the fluid to be administered and pretensioning the piston rod (35, 135) towards the open dispensing end (17); wherein, in a dispensing operation, the tensioning device (S) can release the piston rod (35, 135) when the piston (36) is at the rear end position, so that the pretensioning force causes the piston (36) to move in the opposite direction to the front end position, and in the process, the fluid in the cylinder (16, 116) is dispensed through the check valve (18) for administration; wherein the cylinder (16, 116) is in the form of a replaceable front assembly (13, 14) releasably connected only to the receiving block (10) together with the check valve (18) and a seal which contacts the piston (36) when the piston moves from the forward end position to the rear end position; The apparatus wherein the piston (36) is not part of the replaceable front assembly (13, 14).

2. 2. The device according to claim 1, wherein the releasable connection between the front assembly (13, 14) and the receiving block (10) is a threaded connection.

3. 2. The device of claim 1, wherein the device has a nozzle (19) for administering the fluid without a needle, the nozzle being connected to the open dispensing end of the cylinder (16, 116) via the check valve (18) and being part of the front assembly (13, 14).

4. 2. The device according to claim 1, wherein the tensioning device (S) comprises a spring (41, 141) that pretensions the piston rod (35, 135) towards the open dispensing end when the piston (36) is in the rear end position.

5. 10. The apparatus of claim 1, The tensioning device (S) is rotatable by a motor (12) and has a ramp (52) having a ramp path (53) extending along a spiral line; wherein said ramp (53) rises from a first plateau to a second plateau along an inclined region (S1, S2) and descends from said second plateau to said first plateau via a transition side (46); wherein the tensioning device (S) further comprises a roller (51) in contact with the ramp (53), the roller (51) being rotatably mounted on a driver (50) connected to the end of the piston rod (35, 135) protruding out of the cylinder (16, 116), so that when the ramp (52) rotates, the ramp (53) runs under the roller (51), thereby rotating the roller (51); wherein, in the tensioning operation, the ramp (53), which starts from the roller (51) contacting the first plateau, rotates so that the roller (51) travels on the inclined region to the second plateau, thereby moving the piston (36) to its rear end position; Here, in the dispensing operation, the ramp (53) starts from the contact of the roller (51) with the second plateau and rotates until the roller (51) reaches the first plateau via the transition side (46), thereby moving the piston (36) to its front end position.

6. 6. The device according to claim 5, wherein the motor (12) is mounted on the receiving block (10).

7. 6. The device of claim 5, wherein the sloped area of ​​the ramp (53) has a first portion (S1) adjacent to the first plateau and a second portion (S2) adjacent to the first portion (S1), wherein the slope of the second portion (S2) is greater than the slope of the first portion (S1).

8. 8. The device according to claim 7, wherein the first and second portions (S1, S2) run linearly relative to the angle of rotation of the helical line.

9. 9. The device of claim 8, wherein the angular length of the first portion (S1) is smaller than the angular length of the second portion (S2).

10. 6. The apparatus of claim 5, the roller (51) has a support region (55) that rests on the inclined region (S1, S2) of the ramp (53) and at least one laterally adjacent side region (56, 57) that has an outer diameter smaller than that of the support region (55) and does not rest on the inclined region (S1, S2) of the ramp (53), wherein during the dispensing operation, both the support area (55) and the at least one laterally adjacent side area (56, 57) contact an edge (54) of the ramp (53), said edge connecting the second plateau to the transition side (46).

11. 11. The apparatus of claim 10, The roller (51) has, on either side of the support area (55), at least one laterally adjacent side area (56, 57) having an outer diameter smaller than the outer diameter of the support area (55).

12. 11. The apparatus of claim 10, Device wherein the outer diameter of said at least one laterally adjacent side region (56, 57) decreases in a direction towards the side of said roller (51).

13. 6. The apparatus of claim 5, The roller (51) is mounted on the driver (50) such that the axis of rotation of the roller is perpendicular to the first direction.

14. 2. The device according to claim 1, wherein the receiving block (10) is in the form of a one-piece receiving block (10) manufactured by additive manufacturing.

15. 15. The apparatus of claim 14, The device wherein said receiving block (10) is in the form of a metal receiving block (10).

16. 15. The apparatus of claim 14, The receiving block (10) has a motor bearing (64), a guide cylinder (40, 140) for the piston rod (35, 135), at least one receiving portion (60, 61, 62, 63) for a control board (11), a receiving portion (72, 172) for a fluid connection (33) of a fluid container (M), and / or at least one housing fixing point (65, 66, 67, 68), which are integrally formed with the receiving block (10).

17. 2. The device of claim 1, further comprising at least one supply channel (25), The device, wherein said at least one supply channel (25) is in fluid communication with a cylinder (16, 116) when said piston (36) is in said rear end position.

18. 18. The device of claim 17, wherein the fluid connection between the supply channel (25) and the cylinder (16, 116) comprises an axial blind hole (37) at the distal end of the piston (36) and at least one transverse bore (38) extending radially from the blind hole (37), the end of the at least one transverse bore facing away from the blind hole (37) and leading to one of the at least one supply channel (25).

19. a cylinder (16, 116) having an open dispensing end (17); a piston (36) displaceable within the cylinder (16, 116) between a forward end position and a rear end position, the piston (36) projecting in a first direction beyond the rear end of the cylinder (16, 116) opposite the open dispensing end (17) and connected to a piston rod (35, 135) disposed in a receiving block (10); a check valve (18) closing the open dispensing end (17); a tensioning device (S) connected to the piston rod (35, 135) and arranged on the receiving block (10); At least one supply channel (25) 1. A device for administering a fluid, comprising: wherein the tensioning operation of the tensioning device (S) is such that, when the piston (36) is in the front end position, the tensioning device (S) moves the piston rod (35, 135) along the first direction until the piston (36) is in the rear end position, thereby filling the cylinder (16, 116) with the fluid to be administered and pretensioning the piston rod (35, 135) towards the open dispensing end (17); wherein, in a dispensing operation, the tensioning device (S) can release the piston rod (35, 135) when the piston (36) is at the rear end position, so that the applied pretension causes the piston (36) to move in the opposite direction to the front end position, and in the process, the fluid in the cylinder (16, 116) is dispensed through the check valve (18) for administration; wherein the cylinder (16, 116) together with the check valve (18) are in the form of an exchangeable front assembly (13, 14) releasably connected to the receiving block (10), wherein the piston (36) is not part of the front assembly (13, 14), wherein when the piston (36) is in the rear end position, the at least one supply channel (25) is in fluid communication with the cylinder (16, 116); wherein the fluid connection between the supply channel (25) and the cylinder (16, 116) comprises an axial blind hole (37) at the distal end of the piston (36) and at least one lateral bore (38) extending radially from the blind hole (37), the end of the at least one lateral bore facing away from the blind hole (37) and leading to one of the at least one supply channel (25).

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