Blood purification device

Abstract

To improve workability in attaching a conduit line.SOLUTION: In a blood purification device 1, a first valve 1V is provided in a dialysis fluid conduit line 110 and opens / closes the dialysis fluid conduit line 110. A second valve 2V is provided in a drainage conduit line 120 and opens / closes the drainage conduit line 120. A cover 210 covers at least part of the dialysis fluid conduit line 110, at least part of the drainage conduit line 120, the first valve 1V and the second valve 2V in a closed state. A control part 420 brings the first valve 1V and the second valve 2V into an open state when a signal on a change in the cover 210 from a closed state to an open state is input by a detection part 410, and brings the first valve 1V and the second valve 2V into a closed state when a signal on a change in the cover 210 from an open state to a closed state is input by the detection part 410.SELECTED DRAWING: Figure 1

Description

[Technical Field]

[0001] The present invention relates to a blood purification device. [Background technology]

[0002] The blood purification device is provided with a conduit for flowing a medical fluid. An example of a document disclosing a device equipped with a conduit for flowing a medical fluid is International Publication No. 2013 / 047185 (Patent Document 1). [Prior art documents] [Patent documents]

[0003] [Patent Document 1] International Publication No. 2013 / 047185 Summary of the Invention [Problem to be solved by the invention]

[0004] In blood purification devices, the conduits through which various liquids flow are attached to the valves of the blood purification device before treatment begins. When attaching the conduits, the valves must be opened. After attaching the conduits to the valves, the valves are closed and a bag containing a specific liquid, such as saline, is attached to the conduits. If the bag is attached to the conduits with the valves still open, a so-called free flow occurs, whereby liquid unintentionally flows into the conduits. Thus, in conventional blood purification devices, the valve operation required when attaching the conduits is cumbersome.

[0005] The present invention has been made in view of the above problems, and an object of the present invention is to provide a blood purification apparatus that can improve the workability of pipe installation. [Means for solving the problem]

[0006] A blood purification device according to the present invention comprises a blood purifier, a dialysate line, a drain line, a first valve, a second valve, a main body, a cover, a detection unit, and a control unit. The dialysate line supplies dialysate to the blood purifier. The drain line carries drained fluid discharged from the blood purifier. The first valve is provided in the dialysate line and opens and closes the dialysate line. The second valve is provided in the drain line and opens and closes the drain line. The main body has one side, and the first and second valves are attached to the one side. The cover is attached to cover at least a portion of the one side of the main body so as to be openable and closable. In a closed state, the cover covers at least a portion of the dialysate line, at least a portion of the drain line, the first valve, and the second valve. The detection unit can detect whether the cover is in an open state or a closed state. The control unit is electrically connected to the detection unit, the first valve, and the second valve. The control unit opens each of the first valve and the second valve when a signal indicating that the cover has changed from a closed state to an open state is input from the detection unit, and closes each of the first valve and the second valve when a signal indicating that the cover has changed from an open state to a closed state is input from the detection unit.

[0007] In one embodiment of the present invention, the blood purification device further includes an arterial blood circuit, a venous blood circuit, a fluid replacement line, and a third valve. The arterial blood circuit is connected to the blood purifier and allows blood to flow into the blood purifier. The venous blood circuit is connected to the blood purifier and allows blood to flow out of the blood purifier. The fluid replacement line is connected to the arterial blood circuit or the venous blood circuit and supplies fluid replacement. The third valve is provided in the fluid replacement line and opens and closes the fluid replacement line. The third valve is further attached to one side of the main body. The cover covers at least a portion of the fluid replacement line and the third valve in the closed state. The control unit is further electrically connected to the third valve. The control unit opens the third valve when a signal indicating that the cover has changed from the closed state to the open state is input from the detection unit, and closes the third valve when a signal indicating that the cover has changed from the open state to the closed state is input from the detection unit.

[0008] In one embodiment of the present invention, the blood purification apparatus further includes a connecting conduit, a measuring bag, and a fourth valve. The connecting conduit is connected to a drainage conduit upstream of the second valve. The measuring bag is connected to the end of the connecting conduit opposite the drainage conduit side and is capable of temporarily storing drainage. The fourth valve is provided in the connecting conduit and opens and closes the connecting conduit. The fourth valve is further attached to one side of the main body. The cover covers at least a portion of the connecting conduit and the fourth valve in the closed state. The control unit is further electrically connected to the fourth valve. The control unit opens the fourth valve when a signal indicating that the cover has changed from a closed state to an open state is input from the detection unit, and closes the fourth valve when a signal indicating that the cover has changed from an open state to a closed state is input from the detection unit. [Effects of the Invention]

[0009] According to the present invention, the workability of installing a pipeline can be improved. [Brief explanation of the drawings]

[0010] [Figure 1] 1 is a circuit diagram showing the configuration of a blood purification device according to one embodiment of the present invention. [Figure 2] 1 is a side view of a blood purification device according to an embodiment of the present invention, viewed from one direction. [Figure 3] 1 is a side view of a blood purification apparatus according to an embodiment of the present invention, viewed from one direction, with the cover in a closed state. [Figure 4] FIG. 2 is a perspective view showing a state in which each of the first to fourth valves is in a closed state in one embodiment of the present invention. [Figure 5] FIG. 2 is a perspective view showing a state in which each of the first to fourth valves is in an open state in one embodiment of the present invention. [Figure 6] 1 is a block diagram showing the electrical relationships in the configuration of a blood purification device according to one embodiment of the present invention. DETAILED DESCRIPTION OF THE INVENTION

[0011] A blood purification apparatus according to one embodiment of the present invention will be described below with reference to the drawings. In the following description of the embodiment, the same or corresponding parts in the drawings will be given the same reference numerals, and their description will not be repeated.

[0012] In the following description of the embodiments, a blood purification device used in Continuous Renal Replacement Therapy (CRRT) will be described. However, the blood purification device may also be a blood purification device used in any of continuous hemodiafiltration (CHDF), continuous hemofiltration (CHF), continuous hemodialysis (CHD), and slow continuous ultrafiltration (SCUF).

[0013] First, the circuitry of the blood purification device according to this embodiment will be mainly described. Fig. 1 is a circuit diagram showing the configuration of a blood purification device according to one embodiment of the present invention. As shown in Fig. 1, the blood purification device 1 according to this embodiment includes a blood purifier 100, a dialysate line 110, a drainage line 120, an arterial blood circuit 130, a venous blood circuit 140, a replacement fluid line 150, a (first) connecting line 160, a (first) measuring bag 165, a second connecting line 170, a second measuring bag 175, a scale 180, a syringe pump 190, a first valve 1V, a second valve 2V, a third valve 3V, and a fourth valve 4V.

[0014] The blood purifier 100 includes a semipermeable membrane, such as a hollow fiber membrane, inside. The blood purifier 100 has a dialysate inlet 101, a waste fluid outlet 102, a blood inlet 103, and a blood outlet 104.

[0015] The dialysate conduit 110 is connected to a dialysate inlet 101 of the blood purifier 100 and supplies the dialysate to the blood purifier 100. The upstream end of the dialysate conduit 110 is connected to a first supply source 115 that supplies a first fluid 10, which is a replacement fluid and a dialysate. A dialysate pump 111 that pumps the dialysate is connected to the dialysate conduit 110. The dialysate pump 111 is a peristaltic pump, but may be a roller pump. A first heater 112 that heats the dialysate is provided downstream of the dialysate pump 111 in the dialysate conduit 110. The first heater 112 does not necessarily have to be provided. The dialysate that flows through the dialysate conduit 110 is supplied into the blood purifier 100. The dialysate conduit 110 and the other conduits described below are soft tubes made of, for example, polyvinyl chloride or polybutadiene.

[0016] The drainage pipeline 120 is connected to the drainage outlet 102 of the blood purifier 100, and carries the drainage discharged from the drainage outlet 102 of the blood purifier 100. The drainage discharged from the blood purifier 100 is discharged from the downstream end of the drainage pipeline 120. A drainage pump 121 is connected to the drainage pipeline 120, and sends out the drainage flowing through the drainage pipeline 120. The drainage pump 121 is a peristaltic pump, but may also be a roller pump. A drainage pressure measuring device 122 that measures the pressure inside the drainage pipeline 120 is provided upstream of the drainage pump 121 in the drainage pipeline 120.

[0017] The arterial blood circuit 130 is connected to the blood inlet 103 of the blood purifier 100, and is a circuit for allowing blood to flow into the blood purifier 100. The arterial blood circuit 130 is provided with a blood pump 131 that pumps out blood. In the arterial blood circuit 130, an arterial air trap chamber 132 is provided between the blood pump 131 and the blood purifier 100. The arterial air trap chamber 132 is provided with an arterial pressure measuring device 133 that measures the pressure inside the arterial air trap chamber 132. The arterial blood circuit 130 is provided with an arterial on-off valve 135 that opens and closes the arterial blood circuit 130.

[0018] Blood collected from a patient's artery flows through the arterial blood circuit 130, has its pressure measured as it passes through the arterial air trap chamber 132, and then flows into the blood purifier 100 from the blood inlet 103. The arterial air trap chamber 132 is provided to prevent air from mixing with the blood in the arterial blood circuit 130.

[0019] A priming solution line 136 is further connected to the arterial blood circuit 130. The priming solution line 136 is connected between the arterial on-off valve 135 and the blood pump 131 in the arterial blood circuit 130, and supplies the priming solution 20. The priming solution line 136 is provided with a priming solution valve 137 that opens and closes the priming solution line 136. The priming solution 20 is, for example, physiological saline.

[0020] An airless monitor 138 is also connected to the arterial blood circuit 130. Specifically, the airless monitor 138 is connected between the connection part of the arterial blood circuit 130 with the priming solution line 136 and the blood pump 131. A venting blood pressure measuring device 139 is connected to the airless monitor 138, and measures the venting blood pressure of the patient flowing into the arterial blood circuit 130.

[0021] The venous blood circuit 140 is connected to the blood outlet 104 of the blood purifier 100, and is a circuit for allowing blood to flow out of the blood purifier 100. The venous blood circuit 140 is provided with a venous air trap chamber 141. The venous air trap chamber 141 is provided with a venous pressure measuring device 142 that measures the pressure inside the venous air trap chamber 141. The venous blood circuit 140 is provided with a venous on-off valve 144 that opens and closes the venous blood circuit 140.

[0022] The blood purified by the blood purifier 100 flows through the venous blood circuit 140, has its pressure measured as it passes through the venous air trap chamber 141, and is then returned to the patient's veins. The venous air trap chamber 141 is provided to prevent air from mixing with the blood in the venous blood circuit 140.

[0023] The replacement fluid line 150 is connected to the arterial blood circuit 130 or the venous blood circuit 140 and supplies replacement fluid. In this embodiment, the replacement fluid line 150 is connected to the venous blood circuit 140 and supplies the first fluid 10 as replacement fluid to the venous blood circuit 140. That is, in this embodiment, the blood purification apparatus 1 employs a so-called post-dilution method. Specifically, the replacement fluid line 150 is connected to the venous air trap chamber 141. The replacement fluid that flows through the replacement fluid line 150 is supplied into the venous air trap chamber 141. The blood purification apparatus 1 can also employ a so-called pre-dilution method. When the pre-dilution method is employed, the replacement fluid line 150 is connected to the arterial blood circuit 130.

[0024] A replacement fluid pump 151 that pumps replacement fluid is connected to the replacement fluid line 150. The replacement fluid pump 151 is a peristaltic pump, but may also be a roller pump. A second heater 152 that heats the replacement fluid is provided downstream of the replacement fluid pump 151 in the replacement fluid line 150. Note that the second heater 152 does not necessarily have to be provided.

[0025] The first connecting conduit 160 is connected to the drainage conduit 120. Specifically, the first connecting conduit 160 is connected to the drainage conduit 120 downstream of the drainage pump 121. The first measuring bag 165 is connected to the end of the first connecting conduit 160 opposite to the drainage conduit 120 side, and is capable of temporarily storing the drainage liquid and discharging the stored drainage liquid. The first measuring bag 165 is a soft bag without any holes for venting air.

[0026] The second connecting conduit 170 is connected to the replacement fluid conduit 150. Specifically, the second connecting conduit 170 is connected to the replacement fluid conduit 150 on the upstream side of the replacement fluid pump 151. The second measuring bag 175 is connected to the end of the second connecting conduit 170 opposite to the replacement fluid conduit 150 side, and is capable of temporarily storing the first liquid 10 (as replacement fluid) and discharging the stored first liquid 10 (as replacement fluid). The second measuring bag 175 is a soft bag without any holes for venting air.

[0027] The scale 180 has an attachment portion 181 and a measuring portion (not shown). The first weighing bag 165 and the second weighing bag 175 are attached to the attachment portion 181. The measuring portion is connected to the attachment portion 181 and measures the overall change in weight of the first weighing bag 165 and the second weighing bag 175 attached to the attachment portion 181. In this embodiment, the scale 180 is a load cell. However, the scale 180 is not limited to a load cell and may be a spring balance or the like.

[0028] The syringe pump 190 is connected to the arterial blood circuit 130 via a syringe pump line 191. Specifically, the syringe pump line 191 is connected to the arterial blood circuit 130 upstream of the arterial on-off valve 135. The syringe pump 190 supplies a medicinal liquid 30 into the arterial blood circuit 130. The medicinal liquid 30 is, for example, an anticoagulant such as heparin or nafamostat.

[0029] The first valve 1V is provided in the dialysate line 110 and opens and closes the dialysate line 110. Specifically, the first valve 1V is provided in the dialysate line 110 upstream of the connection position with the replacement fluid line 150.

[0030] The second valve 2V is provided in the drainage pipeline 120 and opens and closes the drainage pipeline 120. Specifically, the second valve 2V is provided in the drainage pipeline 120 downstream of the connection position with the first connecting pipeline 160. In other words, the first connecting pipeline 160 is connected to the drainage pipeline 120 upstream of the second valve 2V.

[0031] The third valve 3V is provided in the fluid replacement line 150, and opens and closes the fluid replacement line 150. The third valve 3V is provided in the fluid replacement line 150 upstream of the connection position with the second connection line 170.

[0032] The fourth valve 4V is provided in the first connecting pipe 160 and opens and closes the first connecting pipe 160. When the fourth valve 4V closes the first connecting pipe 160, the measurement unit of the scale 180 can measure the change in weight of the second weighing bag 175.

[0033] Next, the configuration of the blood purification device 1 will be mainly described. Fig. 2 is a side view of a blood purification device according to one embodiment of the present invention, viewed from one direction. As shown in Fig. 2, the blood purification device 1 according to this embodiment further includes a main body 200 and a cover 210. The main body 200 has one side surface 201, to which a first valve 1V, a second valve 2V, a third valve 3V, and a fourth valve 4V are attached.

[0034] The scale 180 is incorporated into the main body 200, and the mounting portion 181 is positioned on the main body 200 so as to face the same side as the one side 201. The mounting portion 181 is positioned so as to form approximately the same plane as the one side 201. The mounting portion 181 is positioned above the first valve 1V, the second valve 2V, the third valve 3V, and the fourth valve 4V. Therefore, the first weighing bag 165 and the second weighing bag 175 are also positioned above the first valve 1V, the second valve 2V, the third valve 3V, and the fourth valve 4V.

[0035] A first housing section 202 and a second housing section 203 are further attached to one side surface 201 of the main body section 200. The first housing section 202 houses the dialysis fluid pump 111, the drainage pump 121, and the replacement fluid pump 151. This prevents the various pumps from coming into contact with other objects or people. The first housing section 202 is positioned approximately horizontally when viewed from the first valve 1V, the second valve 2V, the third valve 3V, and the fourth valve 4V. The second housing section 203 houses the first heater 112 and the second heater 152. This prevents heat from escaping from the various heaters to the outside of the blood purification device 1, improving the thermal efficiency of the various heaters.

[0036] Fig. 3 is a side view of a blood purification apparatus according to one embodiment of the present invention, viewed from one direction, with the cover in a closed state. As shown in Figs. 2 and 3, cover 210 is attached to main body 200 so as to be openable and closable, covering at least a portion of one side surface 201 of main body 200. Cover 210 is attached to main body 200 by, for example, a hinge. Fig. 2 shows blood purification apparatus 1 with cover 210 in an open state.

[0037] When the main body 200 is viewed from one side 201, the cover 210, in the closed state, covers at least a portion of the dialysis fluid line 110, at least a portion of the drainage line 120, at least a portion of the replacement fluid line 150, at least a portion of the first connecting line 160 (specifically, the entire first connecting line 160), the first measuring bag 165, at least a portion of the second connecting line 170 (specifically, the entire second connecting line 170), the second measuring bag 175, the mounting portion 181 of the scale 180, the first valve 1V, the second valve 2V, the third valve 3V, the fourth valve 4V, and the first storage section 202 (i.e., the dialysis fluid pump 111, the drainage pump 121, and the replacement fluid pump 151).

[0038] Covering the first valve 1V, the second valve 2V, the third valve 3V, and the fourth valve 4V with the cover 210 prevents the operator or patient from coming into contact with each valve during operation, thereby improving safety for the operator and the patient. Covering the entire first connecting conduit 160, the entire first measuring bag 165, the entire second connecting conduit 170, and the mounting portion 181 of the scale 180 with the cover 210 prevents the operator or patient from touching these bags or the scale during operation of the blood purification apparatus 1, thereby enabling more accurate measurement of the weights of the first measuring bag 165 and the second measuring bag 175. Covering the first housing portion 202 (i.e., the dialysate pump 111, the drainage pump 121, and the replacement fluid pump 151) with the cover 210 improves safety for the operator or patient operating the blood purification apparatus 1, even during pump operation.

[0039] The second housing section 203 is attached to one side surface 201 at a position that is not covered by the cover 210 even when the cover 210 is in the closed state. This makes it possible to prevent the heat from the first heater 112 and the second heater 152 housed in the second housing section 203 from being excessively trapped inside the cover 210 when the cover 210 is in the closed state.

[0040] The cover 210 further has a light-transmitting panel 211, and is configured so that the interior of the cover 210 can be seen from the outside of the cover 210 through the light-transmitting panel 211 even when the cover 210 is closed. When the blood purification apparatus 1 is viewed from one side surface 201 with the cover 210 closed, the light-transmitting panel 211 is located in a position such that at least the first weighing bag 165 and the second weighing bag 175 are visible from the outside.

[0041] The cover 210 is further formed with a first notch 212 and a second notch 213. When the blood purification apparatus 1 is viewed from the one side surface 201, the first notch 212 is located on the side surface of the cover 210. When the cover 210 is in the closed state, a portion of the dialysate line 110 that is downstream from the dialysate pump 111 and a portion of the replacement fluid line 150 that is downstream from the replacement fluid pump 151 are arranged to face the hole formed by the first notch 212 and the one side surface 201. This allows the dialysate line 110 and the replacement fluid line 150 to be easily inserted into the hole formed by the first notch 212 and the one side surface 201.

[0042] When the blood purification apparatus 1 is viewed from the one side surface 201 side, the second cutout 213 is located below the cover 210. In addition, a guide portion 214 is further provided on the one side surface 201, and an upstream portion of the drainage pipeline 120 as seen from the drainage pump 121 is fixed to the guide portion 214. The guide portion 214 also positions the upstream portion of the drainage pipeline 120 as seen from the drainage pump 121 so that it faces downward as it moves away from the drainage pump 121. As a result, when the cover 210 is in the closed state, the upstream portion of the drainage pipeline 120 as seen from the drainage pump 121 is positioned so that it faces the hole formed by the second cutout 213 and the one side surface 201. As a result, the drainage pipeline 120 can be easily inserted into the hole formed by the second cutout 213 and the one side surface 201. When the cover 210 is in the closed state, the upstream portion of the dialysis fluid line 110 as viewed from the first valve 1V and the downstream portion of the drainage line 120 as viewed from the second valve 2V are also positioned to face the hole formed by the second cutout portion 213 and one side surface 201.

[0043] As described above, for each of the three pipelines extending directly from each pump, the dialysate pipeline 110 and the replacement fluid pump 151 are led out from the first notch 212, and the drainage pipeline 120 is led out from the second notch 213. This prevents the operator from confusing these pipelines.

[0044] Note that the components of the blood purification apparatus 1 that are attached to one side surface 201 are not limited to the above-described components. In this embodiment, components of the blood purification apparatus 1 other than the above-described components may be attached to other side surfaces or the top surface of the main body 200, or may be separate components from the main body 200.

[0045] Fig. 4 is a perspective view showing a state in which each of the first to fourth valves is in a closed state in one embodiment of the present invention. Fig. 5 is a perspective view showing a state in which each of the first to fourth valves is in an open state in one embodiment of the present invention. In the following, the detailed structure of the first valve 1V will be described, and for the second valve 2V, third valve 3V, and fourth valve 4V, the same components as those of the first valve 1V will be assigned the same reference numerals, and description thereof will not be repeated.

[0046] As shown in FIGS. 4 and 5, the first valve 1V includes an open end 310, a plate-shaped portion 320, a connecting portion 330, and a biasing portion 340.

[0047] Open end 310 has a substantially rectangular outer shape when main body 200 is viewed from one side surface 201. Open end 310 is provided on one side surface 201, and forms a substantially rectangular opening 311 in one side surface 201.

[0048] Plate-shaped portion 320 has a substantially rectangular outer shape when main body 200 is viewed from one side surface 201. Plate-shaped portion 320 is positioned to be spaced apart from opening edge 310 and to face opening 311.

[0049] Connection portion 330 connects open end portion 310 and plate-shaped portion 320. Plate-shaped portion 320 extends in the vertical direction, and connects only one side of open end portion 310 to only one side of plate-shaped portion 320 when main body portion 200 is viewed from one side surface 201. This makes it easy to attach dialysate pipeline 110 to first valve 1V.

[0050] At least a portion of the biasing unit 340 is located inside the opening 311. The biasing unit 340 is configured to be movable along the opposing direction between the opening 311 and the plate-shaped unit 320 by a drive mechanism such as an air cylinder or an actuator. The dialysate pipe 110 is disposed between the opening 311 and the plate-shaped unit 320. The biasing unit 340 is configured to be able to bias the dialysate pipe 110 disposed at the above position in the direction from the opening 311 toward the plate-shaped unit 320. When the biasing unit 340 biases the dialysate pipe 110 so as to press it against the plate-shaped unit 320, the first valve 1V is in a closed state in which it closes the dialysate pipe 110. Then, the biasing unit 340 moves relatively away from the plate-shaped unit 320, thereby releasing the bias of the dialysate pipe 110 by the biasing unit 340. At this time, the first valve 1V is in an open state in which it opens the dialysate pipe 110.

[0051] The dialysate line 110 in the first valve 1V corresponds to the drain line 120, the replacement fluid line 150, and the first connecting line 160 in the second valve 2V, the third valve 3V, and the fourth valve 4V, respectively.

[0052] Next, the control of the blood purification device 1 will be mainly described. FIG. 6 is a block diagram showing the electrical relationships in the configuration of a blood purification device according to one embodiment of the present invention. As shown in FIG. 6, the blood purification device 1 according to this embodiment further includes a detection unit 410 and a control unit 420. As shown in FIGS. 2, 3, and 6, the detection unit 410 can detect whether the cover 210 is open or closed. In this embodiment, the detection unit 410 is provided on the main body 200, but it may also be provided on the cover 210. The specific type of the detection unit 410 is not particularly limited. In this embodiment, the detection unit 410 is a magnetic sensor, more specifically, a Hall element. A magnet (not shown) is provided on the cover 210 at a position corresponding to the detection unit 410. As a result, the detection unit 410, which is a magnetic sensor, can detect the open / closed state of the cover 210 by detecting the magnet on the cover 210. The detection unit 410 may be, for example, a distance sensor. Examples of distance sensors include a reflective photoelectric sensor, a capacitance sensor, or an ultrasonic sensor.

[0053] The control unit 420 is electrically connected to the detection unit 410, the first valve 1V, the second valve 2V, the third valve 3V, and the fourth valve 4V. In this embodiment, the control unit 420 may also be electrically connected to other valves, various pumps, the scale 180, and the like in the blood purification apparatus 1. The control unit 420 includes, for example, a CPU (Central Processing Unit) and memory (neither of which is shown). The CPU executes a program stored in the memory to input signals to open or close the first valve 1V, the second valve 2V, the third valve 3V, and the fourth valve 4V, depending on the status of each mode of the blood purification apparatus 1. The CPU may be realized as the CPU of a microcomputer.

[0054] When the blood purification apparatus 1 is not performing blood purification and is in a preparation mode for attaching each pipeline, the control unit 420 opens each of the first valve 1V, the second valve 2V, the third valve 3V, and the fourth valve 4V upon receiving a signal from the detection unit 410 indicating that the cover 210 has changed from the closed state to the open state, and closes each of the first valve 1V, the second valve 2V, the third valve 3V, and the fourth valve 4V upon receiving a signal from the detection unit 410 indicating that the cover 210 has changed from the open state to the closed state. Specifically, the memory of the control unit 420 stores a program for transmitting an open / close signal to each valve based on the input signal from the detection unit 410, as described above.

[0055] As described above, in the blood purification apparatus 1 according to this embodiment, the first valve 1V is provided in the dialysate line 110 and opens and closes the dialysate line 110. The second valve 2V is provided in the drain line 120 and opens and closes the drain line 120. In the closed state, the cover 210 covers at least a portion of the dialysate line 110, at least a portion of the drain line 120, the first valve 1V, and the second valve 2V. When the control unit 420 receives a signal from the detection unit 410 indicating that the cover 210 has changed from the closed state to the open state, the control unit 420 opens each of the first valve 1V and the second valve 2V, and when the control unit 420 receives a signal from the detection unit 410 indicating that the cover 210 has changed from the open state to the closed state, the control unit 420 closes each of the first valve 1V and the second valve 2V.

[0056] The above configuration improves the workability of attaching the dialysate line 110 and the drain line 120. This work will be described below.

[0057] First, when attaching the dialysate conduit 110 to the first valve 1V and the drain conduit 120 to the second valve 2V, the operator changes the cover 210 from the closed state to the open state. When the cover 210 changes from the closed state to the open state, the control unit 420 opens the first valve 1V and the second valve 2V, eliminating the need for the operator to open the valves. After attaching the dialysate conduit 110 to the first valve 1V and the drain conduit 120 to the second valve 2V, the operator changes the cover 210 to the closed state. When the cover 210 changes to the closed state, the control unit 420 closes the first valve 1V and the second valve 2V, eliminating the need for the operator to close the valves. Furthermore, if a bag containing dialysate is attached to the dialysate conduit 110 thereafter, free flow to the dialysate conduit 110 and the drain conduit 120 is suppressed. As described above, in the blood purification device 1 according to this embodiment, the workability of attaching the dialysate line 110 and the drain line 120 is improved.

[0058] Furthermore, in the blood purification apparatus 1 according to this embodiment, the third valve 3V is provided in the fluid replacement line 150 and opens and closes the fluid replacement line 150. In the closed state, the cover 210 covers at least a portion of the fluid replacement line 150 and the third valve 3V. When a signal indicating that the cover 210 has changed from the closed state to the open state is input from the detection unit 410, the third valve 3V is set to the open state, and when a signal indicating that the cover 210 has changed from the open state to the closed state is input from the detection unit 410, the third valve 3V is set to the closed state.

[0059] The above configuration can improve the workability of attaching the fluid replacement line 150. This work will be described below.

[0060] First, when attaching the fluid replacement line 150 to the third valve 3V, the operator opens the cover 210. When the cover 210 is open, the control unit 420 opens the third valve 3V, eliminating the need for the operator to open the valve. After attaching the fluid replacement line 150 to the third valve 3V and attaching the fluid replacement line 150 to the third valve 3V, the operator closes the cover 210. When the cover 210 is closed, the control unit 420 closes the third valve 3V, eliminating the need for the operator to close the valve. Furthermore, if a bag containing a fluid replacement line 150 is subsequently attached to the fluid replacement line 150, free flow into the fluid replacement line 150 is suppressed. Thus, in the blood purification device 1 according to this embodiment, the ease of attaching the fluid replacement line 150 is improved.

[0061] Furthermore, in the blood purification apparatus 1 according to this embodiment, the first connecting conduit 160 is connected to the drainage conduit 120 at a position upstream of the second valve 2V. A first measuring bag 165 is connected to the end of the first connecting conduit 160 opposite the drainage conduit 120 and is capable of temporarily storing the drainage. A fourth valve 4V is provided in the first connecting conduit 160 and opens and closes the first connecting conduit 160. In the closed state, the cover 210 covers at least a portion of the first connecting conduit 160 and the fourth valve 4V. The controller 420 opens the fourth valve 4V when a signal indicating that the cover 210 has changed from the closed state to the open state is input from the detector 410, and closes the fourth valve 4V when a signal indicating that the cover 210 has changed from the open state to the closed state is input from the detector 410.

[0062] The above configuration improves the workability of attaching the first connecting pipeline 160. This work will be described below.

[0063] First, when attaching the first connecting conduit 160 to the fourth valve 4V, the operator opens the cover 210. When the cover 210 is open, the controller 420 opens the fourth valve 4V, eliminating the need for the operator to open or close the valve. After attaching the first connecting conduit 160 to the fourth valve 4V and attaching the first connecting conduit 160 to the fourth valve 4V, the operator closes the cover 210. When the cover 210 is closed, the controller 420 closes the fourth valve 4V, eliminating the need for the operator to open or close the valve. Furthermore, when a bag containing dialysate is subsequently attached to the dialysate conduit 110, free flow into the first connecting conduit 160 is further suppressed. As described above, the blood purification apparatus 1 according to this embodiment improves the ease of attaching the first connecting conduit 160.

[0064] The embodiments disclosed herein should be considered to be illustrative in all respects and not restrictive. The scope of the present invention is defined by the claims, not by the above description, and is intended to include all modifications within the meaning and scope of the claims. [Explanation of symbols]

[0065] 1 Blood purification device, 1V First valve, 2V Second valve, 3V Third valve, 4V Fourth valve, 10 First fluid, 20 Priming fluid, 30 Drug solution, 100 Blood purifier, 101 Dialysis fluid inlet, 102 Drainage fluid outlet, 103 Blood inlet, 104 Blood outlet, 110 Dialysis fluid line, 111 Dialysis fluid pump, 112 First heater, 115 First supply source, 120 Drainage fluid line, 121 Drainage fluid pump, 122 Drainage fluid pressure measuring device, 130 Arterial side blood circuit, 131 Blood pump, 132 Arterial side air trap chamber, 133 Arterial side pressure measuring device, 135 Arterial side opening / closing valve, 136 Priming fluid line, 137 Priming fluid valve, 138 Airless monitor, 139 Venous blood pressure measuring device, 140 Venous side blood circuit, 141 Venous side air trap chamber, 142 venous side pressure measuring device, 144 venous side on-off valve, 150 infusion line, 151 infusion pump, 152 second heater, 160 (first) connecting line, 165 (first) measuring bag, 170 second connecting line, 175 second measuring bag, 180 scale, 181 mounting portion, 190 syringe pump, 191 syringe pump line, 200 main body portion, 201 one side surface, 202 first storage portion, 203 second storage portion, 210 cover, 211 light-transmitting panel, 212 first notch portion, 213 second notch portion, 214 guide portion, 310 opening end, 311 opening, 320 plate-shaped portion, 330 connecting portion, 340 biasing portion, 410 detection portion, 420 control portion.

Claims

1. Blood purifier and a dialysate line for supplying dialysate to the blood purifier; a drainage pipe through which the drainage liquid discharged from the blood purifier flows; a first valve provided in the dialysate line for opening and closing the dialysate line; a second valve provided in the drainage pipe line for opening and closing the drainage pipe line; a main body having one side surface to which the first valve and the second valve are attached; a cover that is attached to cover at least a portion of the one side surface of the main body in an openable and closable manner, and that covers at least a portion of the dialysate line, at least a portion of the drain line, the first valve, and the second valve in a closed state; a detection unit capable of detecting whether the cover is in an open state or a closed state; a control unit electrically connected to the detection unit, the first valve, and the second valve, the control unit opening each of the first valve and the second valve when a signal indicating that the cover has changed from a closed state to an open state is input from the detection unit, and closing each of the first valve and the second valve when a signal indicating that the cover has changed from an open state to a closed state is input from the detection unit.

2. an arterial blood circuit connected to the blood purifier for allowing blood to flow into the blood purifier; a venous blood circuit connected to the blood purifier for allowing blood to flow out of the blood purifier; a fluid replacement line connected to the arterial blood circuit or the venous blood circuit for supplying a replacement fluid; a third valve provided in the fluid replacement line for opening and closing the fluid replacement line; the third valve is further attached to the one side surface of the main body, the cover covers at least a portion of the replacement fluid line and the third valve in a closed state; 2. The blood purification apparatus according to claim 1, wherein the control unit is further electrically connected to the third valve, and opens the third valve when a signal indicating that the cover has changed from a closed state to an open state is input from the detection unit, and closes the third valve when a signal indicating that the cover has changed from an open state to a closed state is input from the detection unit.

3. a connecting pipe connected to the drainage pipe upstream of the second valve; a measuring bag connected to an end of the connecting pipe line opposite to the drainage pipe line side, the measuring bag being capable of temporarily storing the drainage liquid; a fourth valve provided in the connecting pipe line for opening and closing the connecting pipe line, the fourth valve is further attached to the one side surface of the main body, the cover covers at least a portion of the connecting pipe line and the fourth valve in a closed state; 3. The blood purification apparatus according to claim 1, wherein the control unit is further electrically connected to the fourth valve, and opens the fourth valve when a signal indicating that the cover has changed from a closed state to an open state is input from the detection unit, and closes the fourth valve when a signal indicating that the cover has changed from an open state to a closed state is input from the detection unit.

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