Therapeutic device for controlling deep transcranial magnetic stimulation

Abstract

To provide a treatment device for deep part transcranial magnetic stimulatory adjustment.SOLUTION: Regarding a field of medical equipment, upper-level computer control software transmits a stimulation command to a system main control module in accordance with set parameter data and, when the system main control module receives the stimulation command, transmits a control enable signal to a stimulation coil excitation power supply module, and a stimulation coil excitation power supply module supplies a deep part stimulation coil module with current in accordance with a control enable signal. The deep part stimulation coil module generates an overlapping magnetic field and transmits it to a target area. The deep part stimulation coil module includes coil groups of multi-group. Each of the coil groups includes two coils. Magnetic fields of the coil groups of multi-group have overlapping parts, and the overlapping parts are installed in correspondence with a set target area.SELECTED DRAWING: Figure 1

Description

[Technical Field]

[0001] The present invention relates to the field of medical devices, and more particularly to a therapeutic device for deep transcranial magnetic stimulation control. [Background technology]

[0002] Transcranial magnetic stimulation (TMS) is a non-invasive human brain stimulation technique that modulates neural tissue function by delivering overlapping pulsed magnetic fields. Extensive clinical studies have demonstrated its effectiveness and safety in treating brain dysfunction. Conventional magnetic stimulation modules, including ring coils, "eight"-shaped coils, double-cone coils, and H-shaped coils, typically provide stimulation depths of 2-3 cm, with the deepest reaching no more than 6 cm (H-shaped coils). Therefore, current magnetic stimulation methods cannot effectively reach deep brain tissues, such as the temporal lobe, basal ganglia, and thalamus. They can only be used to modulate superficial brain regions, limiting their clinical applications.

[0003] Currently, all modulation technologies that can reach deep brain tissues such as the temporal lobe, basal ganglia, and thalamus are creative technologies. For example, deep brain stimulation (DBS) is expensive and cannot adjust the target once implanted. There is no non-invasive neuromodulation technology that can replace DBS. Summary of the Invention [Problem to be solved by the invention]

[0004] The present invention aims to provide a therapeutic device for deep transcranial magnetic stimulation regulation, which generates a superposed electromagnetic field to achieve precise delivery of a non-invasive transcranial magnetic field into the skull. [Means for solving the problem]

[0005] In order to achieve the above object, the present invention provides the following solutions.

[0006] The therapeutic device for controlling deep transcranial magnetic stimulation includes host computer control software, a system main control module, a stimulation coil excitation power supply module, and a deep stimulation coil module.

[0007] The output terminal of the upper computer control software is connected to the input terminal of the system main control module, the output terminal of the system main control module is connected to the control terminal of the stimulation coil excitation power supply module, and the output terminal of the stimulation coil excitation power supply module is connected to the input terminal of the deep stimulation coil module.

[0008] The host computer control software is used to send stimulation commands to the system main control module according to set parameter data, which includes target area, excitation time and excitation current.

[0009] The system master control module is used to send a control enable signal to the stimulation coil excitation power supply module when it receives a stimulation command.

[0010] The stimulation coil excitation power supply module is used to provide current to the deep stimulation coil module in response to a control enable signal.

[0011] The deep stimulation coil module is used to generate and transmit a superposed magnetic field to a target region.

[0012] The deep stimulation coil module includes multiple coil groups, each of which includes two coils, and the magnetic fields of the multiple coil groups have overlapping portions, which are positioned corresponding to the set target area. [Effects of the Invention]

[0013] According to specific embodiments provided by the present invention, the present invention discloses the following technical effects: The present invention realizes that the non-invasive transcranial magnetic field accurately reaches the deep brain region by controlling the deep stimulation coil module to generate and transmit the superimposed magnetic field to the target region. [Brief explanation of the drawings]

[0014] In order to more clearly describe the embodiments of the present invention or the technical solutions in the prior art, the following briefly describes the figures that need to be used in the embodiments. Obviously, the figures in the following description are only some embodiments of the present invention, and those skilled in the art can further obtain other figures based on these figures without any creative efforts.

[0015] [Figure 1] 1 is a structural diagram of a therapeutic device for controlling deep transcranial magnetic stimulation in an embodiment of the present invention. [Figure 2] FIG. 2 is a structural diagram of a stimulation module in an embodiment of the present invention. DETAILED DESCRIPTION OF THE INVENTION

[0016] The following provides a clear and complete description of the technical solutions in the embodiments of the present invention with reference to the figures in the embodiments of the present invention, and it is obvious that the described embodiments are only some of the embodiments of the present invention, and not all of the embodiments, and all other embodiments obtained by those skilled in the art based on the embodiments of the present invention without any creative efforts fall within the scope of protection of the present invention.

[0017] The present invention aims to deliver non-invasive transcranial magnetic fields accurately into the skull, generating induced currents and biological effects in the target area without damaging the neural tissue in the area through which the magnetic field passes. Multiple magnetic stimulation modules are intended to focus on the same target deep in the brain from different directions (similar to the principle of radiation therapy), with the cumulative magnetic field on each path being much smaller than the magnetic field at the target, resulting in a weak effect and generating a magnetic field and induced current with physiological effects in the target. By registering individualized brain magnetic resonance structural images, the design software can simulate pre-stimulation stimulation parameters, allowing for prediction of the target location and physiological effects under the stimulation magnetic field approach and stimulation parameter conditions.

[0018] The present invention aims to provide a therapeutic device for deep transcranial magnetic stimulation regulation, which generates a superposed electromagnetic field to achieve precise delivery of a non-invasive transcranial magnetic field into the skull.

[0019] In order to make the above objects, features and advantages of the present invention more apparent and comprehensible, the present invention will be described in more detail below with reference to the drawings and detailed description of the invention.

[0020] As shown in FIG. 1, the therapeutic device for controlling deep transcranial magnetic stimulation according to the present invention includes an upper computer control software, a system main control module, a stimulation coil excitation power supply module, and a deep stimulation coil module.

[0021] The output terminal of the upper computer control software is connected to the input terminal of the system main control module, the output terminal of the system main control module is connected to the control terminal of the stimulation coil excitation power supply module, and the output terminal of the stimulation coil excitation power supply module is connected to the input terminal of the deep stimulation coil module.

[0022] The upper computer control software is used to send stimulation commands to the system main control module according to set parameter data, which includes target area, excitation time, excitation current, etc.

[0023] In a specific implementation, the target area is determined by the physician through examination of the patient, and stimulation parameters such as excitation time and excitation current are determined by the physician according to the treatment adjustment solution, which is not the focus of the present invention and will not be further described herein.

[0024] The system master control module is used to send a control enable signal to the stimulation coil excitation power supply module when it receives a stimulation command.

[0025] The stimulation coil excitation power supply module is used to provide current to the deep stimulation coil module in response to a control enable signal.

[0026] The deep stimulation coil module is used to generate and transmit a superposed magnetic field to a target region.

[0027] The deep stimulation coil module includes multiple coil groups, each of which includes two coils, and the magnetic fields of the multiple coil groups have overlapping portions, which are positioned corresponding to the set target area.

[0028] In a specific implementation, a simulation experiment is performed according to the acquired position of the target region, thereby determining position data for each coil group, and adjusting each coil group according to the position data of each coil group so that there is an overlapping portion in the magnetic fields generated by the multiple coil groups, and the overlapping portion corresponds to the acquired position of the target region. After the adjustment of the multiple coil groups is completed, the target region is stimulated using the therapeutic device for adjusting deep transcranial magnetic stimulation provided by the present invention. The position data includes three-dimensional coordinates and / or angle data.

[0029] In Figure 2, the same number represents one group of coil groups, all of which have the same current size and direction. Multiple coil groups are arranged in different orientations within the brain, and the superimposed electromagnetic fields generated by each coil group are used to provide modulated stimulation to a target region of the brain. The position and angle of each coil group can be adjusted according to different target regions (the target regions are pre-existing and pre-defined regions in the medical field) to allow the generated electromagnetic fields to be superimposed within the target region. At the same time, the number of multiple coil groups can be increased to provide greater intensity modulated stimulation. The use of multiple coil groups also reduces the requirements for the coil excitation power supply, improving power efficiency and reducing safety risks.

[0030] In one embodiment, the therapeutic device for regulating deep transcranial magnetic stimulation further includes a coil temperature detection module.

[0031] The coil temperature detection module is connected to the system main control module, and the coil temperature detection module is internal to the deep stimulation coil module.

[0032] The coil temperature detection module is used to collect the temperature of the deep stimulation coil module in real time and transmit the temperature to the system main control module, which controls the switch of the stimulation coil excitation power supply module according to the temperature, and the system main control module further transmits the temperature to the upper computer control software, which is used to send a stop command to the system main control module and display temperature fault information when the temperature is greater than a predetermined temperature threshold.

[0033] After the deep stimulation coil module is energized, it generates the electromagnetic field required for modulation to stimulate the brain region. At the same time, the coil temperature detection module is used to detect the temperature of the deep stimulation coil module in real time and transmit the temperature to the system main control module, which uses hardware to control (open / close) the stimulation coil excitation power supply module. The system main control module then transmits the temperature to the upper computer control software, which performs threshold comparison according to the temperature. If the temperature is greater than the predetermined temperature threshold, it will send a stop command to the system main control module. The upper computer control software will also display temperature fault information and alert the fault.

[0034] The deep transcranial magnetic stimulation regulated therapeutic device further includes a power failure detection module.

[0035] The power supply failure detection modules are respectively connected to the system master control module and the stimulation coil excitation power supply module.

[0036] The power supply failure detection module is used to collect the operating status of the stimulation coil excitation power supply module in real time and transmit the operating status to the system main control module, which controls the switch of the stimulation coil excitation power supply module according to the operating status, and when the system main control module controls the closing of the stimulation coil excitation power supply module, it is further used to transmit the closing status of the stimulation coil excitation power supply module to the upper computer control software, which displays the closing status of the stimulation coil excitation power supply module and sends a stop command to the system main control module.

[0037] The stimulation coil excitation power supply module provides an operating current to the deep stimulation coil module according to a signal sent from the system main control module, and at the same time, the power supply failure detection module is used to detect the operating status of the stimulation coil excitation power supply module, and detects an abnormal status signal (detects a power supply digital signal, and determines an abnormal status when the detected digital signal is 0, and determines an abnormal status when the detected digital signal is 1), and then sends it to the system main control module. The system main control module realizes control (open / close) to the stimulation coil excitation power supply module according to the signal sent from the power supply failure detection module.

[0038] By generating superimposed electromagnetic fields, the present invention enables non-invasive transcranial magnetic fields to accurately reach deep brain regions, which are brain regions greater than 6 centimeters deep.

[0039] Each embodiment in this specification is described in stages, and what each embodiment mainly describes is the difference from other embodiments. The same or similar parts between the embodiments may be referred to each other.

[0040] In this specification, specific examples are used to explain the principles and embodiments of the present invention, and the description of the above examples is only useful for understanding the method of the present invention and its core idea, and at the same time, those skilled in the art will be able to change the form and application scope of the invention according to the idea of ​​the present invention. Therefore, the contents of this specification should not be understood as a limitation on the present invention.

Claims

[Claim 1] A therapeutic device for controlling deep transcranial magnetic stimulation, the therapeutic device for controlling deep transcranial magnetic stimulation comprising: a host computer control software, a system main control module, a stimulation coil excitation power supply module, and a deep stimulation coil module; The output end of the host computer control software is connected to the input end of the system main control module, the output end of the system main control module is connected to the control end of the stimulation coil excitation power supply module, and the output end of the stimulation coil excitation power supply module is connected to the input end of the deep stimulation coil module; The host computer control software is used to send stimulation commands to the system main control module according to set parameter data, the parameter data including target area, excitation time and excitation current; the system master control module is adapted to send a control enable signal to the stimulation coil excitation power supply module upon receiving the stimulation command; the stimulation coil excitation power supply module is used to provide current to the deep stimulation coil module in response to the control enable signal; the deep stimulation coil module is used to generate and transmit a superposed magnetic field to a target region; The deep stimulation coil module includes multiple coil groups, each of which includes two coils, and the magnetic fields of the multiple coil groups have overlapping portions, which are located corresponding to the set target region, and the currents introduced into the multiple coil groups are all the same in size and direction, and the multiple coil groups are arranged in different orientations of the brain region; According to the target area, the position and angle of each coil group are adjusted, and the electromagnetic fields generated by each coil group are superimposed in the target area to generate a superimposed electromagnetic field, thereby realizing the non-invasive transcranial magnetic field to accurately reach the deep brain region, which is the brain region with a depth of more than 6 cm. At the same time, by increasing the number of coil groups in multiple groups, it is possible to achieve greater intensity of regulated stimulation. The use of multiple coil groups also reduces the requirements for the coil excitation power supply, improves power usage efficiency, and reduces safety risks. The deep transcranial magnetic stimulation regulated therapeutic device further includes a coil temperature detection module; The coil temperature detection module is connected to the system main control module, and the coil temperature detection module is installed inside the deep stimulation coil module; The coil temperature detection module is used to collect the temperature of the deep stimulation coil module in real time and transmit the temperature to the system main control module, and the system main control module controls the switch of the stimulation coil excitation power supply module according to the temperature, and the system main control module transmits the temperature to the upper computer control software, and the upper computer control software is used to send a stop command to the system main control module and display temperature fault information when the temperature is greater than a predetermined temperature threshold; The deep transcranial magnetic stimulation regulated therapeutic device further includes a power failure detection module; the power supply failure detection module is respectively connected to the system main control module and the stimulation coil excitation power supply module; a power supply failure detection module for collecting the operating status of the stimulation coil excitation power supply module in real time and transmitting the operating status to the system main control module; the system main control module controls a switch of the stimulation coil excitation power supply module according to the operating status; and when controlling the closure of the stimulation coil excitation power supply module, transmits the closure status of the stimulation coil excitation power supply module to the host computer control software; and the host computer control software displays the closure status of the stimulation coil excitation power supply module and sends a stop command to the system main control module.

Images