product

Abstract

To provide an aerosolizable product comprising an aerosol forming material, where the aerosol forming material is infused with smoke from tobacco.SOLUTION: There is further provided an aerosolizable product comprising an aerosol forming material, where the aerosol forming material is selected from polyhydric alcohols (such as glycerol, propylene glycol and triethylene glycol), esters (such as triethyl citrate and triacetin), high boiling point hydrocarbons, non-polyols (such as glycols, sorbitol and lactic acid), and mixtures thereof, and where the aerosol forming material is infused with smoke from a plant material.SELECTED DRAWING: None

Description

FIELD OF THE INVENTION

[0001] The present disclosure relates to aerosolizable products, containers containing the aerosolizable products, and electronic vapor delivery systems, such as electronic delivery systems (e.g., e-cigarettes), that incorporate the aerosolizable products.

[0002] Electronic vapor delivery systems, such as e-cigarettes, generally contain a reservoir of liquid to be vaporized, typically containing nicotine. When a user inhales on the device, a heater is activated, causing a small amount of liquid to vaporize and thus be inhaled by the user.

[0003] E-cigarette use in the UK is growing rapidly, with an estimated 3 million people now using e-cigarettes in the UK.

[0004] One challenge faced in providing such a system is providing a vapor to be inhaled from the vapor delivery device that provides a consumer-satisfying experience. Some consumers may prefer e-cigarettes that generate an aerosol that closely "mimics" the smoke inhaled from a tobacco product, such as a cigarette. The aerosol from an e-cigarette and the smoke from a tobacco product, such as a cigarette, produce a complex cascade of flavors in the user's mouth. These various aspects are described by users in terms of flavor, intensity / quality, impact, and sharpness / smoothness. Each of these elements and their balance can strongly contribute to the consumer's satisfaction with an e-cigarette. Therefore, it is desirable for e-cigarette manufacturers to provide a means to optimize the overall e-cigarette smoking experience. To address these demands, most "e-liquids" are imparted with flavors / aromas by adding specific flavorings to the e-liquid. However, it is still contemplated that these base materials can be improved in terms of the flavors / aromas they provide. Overview

[0005] In one aspect, an aerosolizable product is provided that includes an aerosol-forming material, wherein the aerosol-forming material is infused with tobacco-derived smoke.

[0006] In one aspect, an aerosolizable product is provided that includes an aerosol-forming material, wherein the aerosol-forming material is selected from polyhydric alcohols (e.g., glycerol, propylene glycol, and triethylene glycol), esters (e.g., triethyl citrate and triacetin), high-boiling hydrocarbons, non-polyols (e.g., glycol, sorbitol, and lactic acid), and mixtures thereof (preferably, the aerosol-forming material is selected from glycerol, propylene glycol, and mixtures thereof), and wherein the aerosol-forming material is infused with smoke derived from plant material.

[0007] The aerosol generating means preferably comprises an aerosol forming means and may be, for example, a polyol such as glycerol, propylene glycol and triethylene glycol, or an ester such as triethyl citrate or triacetin, or a high boiling hydrocarbon, or a non-polyol such as glycol, sorbitol or lactic acid.

[0008] In one aspect, (a) a container; (b) an aerosolizable product containing an aerosol-forming material, wherein the aerosol-forming material is infused with tobacco-derived smoke; An aerosolizable product is provided in a container comprising:

[0009] In one aspect, (a) a container; (b) An aerosolizable product comprising an aerosol-forming material, wherein the aerosol-forming material is selected from polyhydric alcohols (e.g., glycerol, propylene glycol, and triethylene glycol), esters (e.g., triethyl citrate and triacetin), high-boiling hydrocarbons, non-polyols (e.g., glycol, sorbitol, and lactic acid), and mixtures thereof, preferably selected from glycerol, propylene glycol, and mixtures thereof, and wherein the aerosol-forming material is infused with smoke derived from plant material. An aerosolizable product is provided in a container comprising:

[0010] In one aspect, (i) an aerosolization device for aerosolizing an aerosolizable product for inhalation by a user of the electronic aerosol delivery system; (ii) a power source, including a cell or battery, for powering the aerosolization device; (iii) an aerosolizable product containing an aerosol-forming material, wherein the aerosol-forming material is infused with tobacco-derived smoke; An electronic aerosol delivery system is provided that includes:

[0011] In one aspect, (i) an aerosolization device for aerosolizing an aerosolizable product for inhalation by a user of the electronic aerosol delivery system; (ii) a power source, including a cell or battery, for powering the aerosolization device; (iii) An aerosolizable product comprising an aerosol-forming material, wherein the aerosol-forming material is selected from polyhydric alcohols (e.g., glycerol, propylene glycol, and triethylene glycol), esters (e.g., triethyl citrate and triacetin), high-boiling hydrocarbons, non-polyols (e.g., glycol, sorbitol, and lactic acid), and mixtures thereof, preferably selected from glycerol, propylene glycol, and mixtures thereof, and wherein the aerosol-forming material is infused with smoke derived from a plant material. An electronic aerosol delivery system is provided that includes:

[0012] In one aspect, there is provided a method for improving the sensory properties of an aerosolizable product, comprising: (a) providing an aerosol-forming material; (b) injecting tobacco smoke into the aerosol-forming material; A method is provided, comprising:

[0013] In one aspect, there is provided a method for improving the sensory properties of an aerosolizable product, comprising: (a) providing an aerosol-forming material selected from polyhydric alcohols (e.g., glycerol, propylene glycol, and triethylene glycol), esters (e.g., triethyl citrate and triacetin), high-boiling hydrocarbons, non-polyols (e.g., glycol, sorbitol, and lactic acid), and mixtures thereof (preferably, the aerosol-forming material is selected from glycerol, propylene glycol, and mixtures thereof); (b) injecting smoke from plant material into the aerosol-forming material; A method is provided, comprising:

[0014] In one aspect, there is provided a use of smoke to improve the sensory properties of an aerosol-forming material.

[0015] As discussed herein, the present invention provides an aerosolizable product comprising an aerosol-forming material, wherein the aerosol-forming material is infused with tobacco-derived smoke; and the present invention provides an aerosolizable product comprising an aerosol-forming material, wherein the aerosol-forming material is selected from polyhydric alcohols (e.g., glycerol, propylene glycol, and triethylene glycol), esters (e.g., triethyl citrate and triacetin), high-boiling hydrocarbons, non-polyols (e.g., glycol, sorbitol, and lactic acid), and mixtures thereof (preferably, the aerosol-forming material is selected from glycerol, propylene glycol, and mixtures thereof), and wherein the aerosol-forming material is infused with smoke derived from plant material.

[0016] The inventors have discovered that the flavor and / or aroma provided by the aerosol-forming material in an aerosolizable product can be enhanced by subjecting the aerosol-forming material, such as glycerol, to smoke derived from plant material, particularly tobacco-derived smoke. Smoke can be generated using various combinations of plant material, such as tobacco alone, tobacco and wood, and wood alone. The generated smoke is then contacted with an aerosol-forming material, such as glycerol.

[0017] For ease of reference, these and further aspects of the present invention are discussed below under appropriate section headings, although the teachings in each section are not necessarily limited to each particular section.

[0018] Aerosol-forming materials

[0019] As discussed herein, when tobacco-derived smoke is injected into the aerosol-forming material, the aerosol-forming material may be any suitable material. As discussed herein, the aerosolizable product comprises an aerosol-forming material. As will be understood by those skilled in the art, "the aerosolizable product comprises an aerosol-forming material" means that the aerosolizable product contains at least one aerosol-forming material. In this specification, reference to an aerosol-forming material can be read as relating to at least one aerosol-forming material.

[0020] The aerosol-forming material can be selected from water, polyhydric alcohols such as glycerol, propylene glycol, and triethylene glycol, or esters such as triethyl citrate or triacetin, or high-boiling hydrocarbons, or non-polyols such as glycol, sorbitol, or lactic acid. The aerosol-forming material can be selected from polyhydric alcohols such as glycerol, propylene glycol, and triethylene glycol, or esters such as triethyl citrate or triacetin, or high-boiling hydrocarbons, or non-polyols such as glycol, sorbitol, or lactic acid. In one aspect, the aerosol-forming material is selected from polyhydric alcohols (e.g., glycerol, propylene glycol, and triethylene glycol), esters (e.g., triethyl citrate and triacetin), high-boiling hydrocarbons, non-polyols (e.g., glycol, sorbitol, and lactic acid), and mixtures thereof. [Preferably, the aerosol-forming material is selected from glycerol, propylene glycol, and mixtures thereof.]

[0021] The aerosol-forming material may be selected from water, triethylene glycol, triethyl citrate, triacetin, glycol, sorbitol, lactic acid, glycerol, propylene glycol, and mixtures thereof.The aerosol-forming material may be selected from triethylene glycol, triethyl citrate, triacetin, glycol, sorbitol, lactic acid, glycerol, propylene glycol, and mixtures thereof.

[0022] In one aspect, the aerosol-forming material is selected from water, glycerol, propylene glycol, and mixtures thereof.In one aspect, the aerosol-forming material is selected from glycerol, propylene glycol, and mixtures thereof.

[0023] In one embodiment, the aerosol-forming material is at least water. In this embodiment, additional aerosol-forming materials may or may not be present. In a further embodiment, the aerosol-forming material comprises water and at least one aerosol-forming material other than water. In one embodiment, the one or more aerosol-forming materials is a mixture of (a) water and (b) glycerol, propylene glycol, or a mixture thereof.

[0024] The aerosol-forming material may be provided in any suitable physical form. In one aspect, the aerosol-forming material is in the form of a gel, liquid, or paste. In one aspect, the aerosol-forming material is in the form of a liquid.

[0025] The one or more aerosol-forming materials may be present in the aerosolizable product in any suitable amount. In one embodiment, the one or more aerosol-forming materials are present in a total amount of at least 5 wt.% of the aerosolizable product. In one embodiment, the one or more aerosol-forming materials are present in a total amount of at least 10 wt.% of the aerosolizable product. In one embodiment, the one or more aerosol-forming materials are present in a total amount of at least 15 wt.% of the aerosolizable product. In one embodiment, the one or more aerosol-forming materials are present in a total amount of at least 20 wt.% of the aerosolizable product. In one embodiment, the one or more aerosol-forming materials are present in a total amount of at least 25 wt.% of the aerosolizable product. In one embodiment, the one or more aerosol-forming materials are present in a total amount of at least 30 wt.% of the aerosolizable product. In one embodiment, the one or more aerosol-forming materials are present in a total amount of at least 35 wt.% of the aerosolizable product. In one embodiment, the one or more aerosol-forming materials are present in a total amount of at least 40 wt.% of the aerosolizable product. In one embodiment, the one or more aerosol-forming materials are present in a total amount of at least 45 wt.% of the aerosolizable product. In one embodiment, the one or more aerosol-forming materials are present in a total amount of at least 50 wt.% of the aerosolizable product. In one embodiment, the one or more aerosol-forming materials are present in a total amount of at least 55 wt.% of the aerosolizable product. In one embodiment, the one or more aerosol-forming materials are present in a total amount of at least 60 wt.% of the aerosolizable product. In one embodiment, the one or more aerosol-forming materials are present in a total amount of at least 65 wt.% of the aerosolizable product. In one embodiment, the one or more aerosol-forming materials are present in a total amount of at least 70 wt.% of the aerosolizable product. In one embodiment, the one or more aerosol-forming materials are present in a total amount of at least 75 wt.% of the aerosolizable product. In one embodiment, the one or more aerosol-forming materials are present in a total amount of at least 80 wt.% of the aerosolizable product.In one embodiment, the one or more aerosol-forming materials are present in a total amount of at least 85 wt.% of the aerosolizable product. In one embodiment, the one or more aerosol-forming materials are present in a total amount of at least 90 wt.% of the aerosolizable product.

[0026] In one embodiment, the one or more aerosol-forming materials are present in a total amount of 5-99 wt.% of the aerosolizable product. In one embodiment, the one or more aerosol-forming materials are present in a total amount of 10-99 wt.% of the aerosolizable product. In one embodiment, the one or more aerosol-forming materials are present in a total amount of 15-99 wt.% of the aerosolizable product. In one embodiment, the one or more aerosol-forming materials are present in a total amount of 20-99 wt.% of the aerosolizable product. In one embodiment, the one or more aerosol-forming materials are present in a total amount of 25-99 wt.% of the aerosolizable product. In one embodiment, the one or more aerosol-forming materials are present in a total amount of 30-99 wt.% of the aerosolizable product. In one embodiment, the one or more aerosol-forming materials are present in a total amount of 35-99 wt.% of the aerosolizable product. In one embodiment, the one or more aerosol-forming materials are present in a total amount of 40-99 wt.% of the aerosolizable product. In one embodiment, the one or more aerosol-forming materials are present in a total amount of 45-99 wt.% of the aerosolizable product. In one embodiment, the one or more aerosol-forming materials are present in a total amount of 50-99 wt.% of the aerosolizable product. In one embodiment, the one or more aerosol-forming materials are present in a total amount of 55-99 wt.% of the aerosolizable product. In one embodiment, the one or more aerosol-forming materials are present in a total amount of 60-99 wt.% of the aerosolizable product. In one embodiment, the one or more aerosol-forming materials are present in a total amount of 65-99 wt.% of the aerosolizable product. In one embodiment, the one or more aerosol-forming materials are present in a total amount of 70-99 wt.% of the aerosolizable product. In one embodiment, the one or more aerosol-forming materials are present in a total amount of 75-99 wt.% of the aerosolizable product. In one embodiment, the one or more aerosol-forming materials are present in a total amount of 80-99 wt.% of the aerosolizable product. In one embodiment, the one or more aerosol-forming materials are present in a total amount of 85-99 wt.% of the aerosolizable product.In one embodiment, the one or more aerosol-forming materials are present in a total amount of 90-99 wt.% of the aerosolizable product.

[0027] In one embodiment, the one or more aerosol-forming materials are present in a total amount of 5-95 wt.% of the aerosolizable product. In one embodiment, the one or more aerosol-forming materials are present in a total amount of 10-95 wt.% of the aerosolizable product. In one embodiment, the one or more aerosol-forming materials are present in a total amount of 15-95 wt.% of the aerosolizable product. In one embodiment, the one or more aerosol-forming materials are present in a total amount of 20-95 wt.% of the aerosolizable product. In one embodiment, the one or more aerosol-forming materials are present in a total amount of 25-95 wt.% of the aerosolizable product. In one embodiment, the one or more aerosol-forming materials are present in a total amount of 30-95 wt.% of the aerosolizable product. In one embodiment, the one or more aerosol-forming materials are present in a total amount of 35-95 wt.% of the aerosolizable product. In one embodiment, the one or more aerosol-forming materials are present in a total amount of 40-95 wt.% of the aerosolizable product. In one embodiment, the one or more aerosol-forming materials are present in a total amount of 45-95 wt.% of the aerosolizable product. In one embodiment, the one or more aerosol-forming materials are present in a total amount of 50-95 wt.% of the aerosolizable product. In one embodiment, the one or more aerosol-forming materials are present in a total amount of 55-95 wt.% of the aerosolizable product. In one embodiment, the one or more aerosol-forming materials are present in a total amount of 60-95 wt.% of the aerosolizable product. In one embodiment, the one or more aerosol-forming materials are present in a total amount of 65-95 wt.% of the aerosolizable product. In one embodiment, the one or more aerosol-forming materials are present in a total amount of 70-95 wt.% of the aerosolizable product. In one embodiment, the one or more aerosol-forming materials are present in a total amount of 75-95 wt.% of the aerosolizable product. In one embodiment, the one or more aerosol-forming materials are present in a total amount of 80-95 wt.% of the aerosolizable product. In one embodiment, the one or more aerosol-forming materials are present in a total amount of 85-95 wt.% of the aerosolizable product.In one embodiment, the one or more aerosol-forming materials are present in a total amount of 90-95 wt.% of the aerosolizable product.

[0028] As discussed herein, in one embodiment, the aerosol-forming material is at least water. Water may be present in the aerosolizable product in any suitable amount. In one embodiment, water is present in a total amount of at least 5 wt.% of the aerosolizable product. In one embodiment, water is present in a total amount of at least 10 wt.% of the aerosolizable product. In one embodiment, water is present in a total amount of at least 15 wt.% of the aerosolizable product. In one embodiment, water is present in a total amount of at least 20 wt.% of the aerosolizable product. In one embodiment, water is present in a total amount of at least 25 wt.% of the aerosolizable product.

[0029] In one embodiment, water is present in a total amount of 5-30 wt.% of the aerosolizable product. In one embodiment, water is present in a total amount of 10-30 wt.% of the aerosolizable product. In one embodiment, water is present in a total amount of 15-30 wt.% of the aerosolizable product. In one embodiment, water is present in a total amount of 20-30 wt.% of the aerosolizable product. In one embodiment, water is present in a total amount of 25-30 wt.% of the aerosolizable product.

[0030] As discussed herein, in one embodiment, the aerosol-forming material is at least glycerol. Glycerol may be present in the aerosolizable product in any suitable amount. In one embodiment, glycerol is present in a total amount of at least 5 wt.% of the aerosolizable product. In one embodiment, glycerol is present in a total amount of at least 10 wt.% of the aerosolizable product. In one embodiment, glycerol is present in a total amount of at least 15 wt.% of the aerosolizable product. In one embodiment, glycerol is present in a total amount of at least 20 wt.% of the aerosolizable product. In one embodiment, glycerol is present in a total amount of at least 25 wt.% of the aerosolizable product. In one embodiment, glycerol is present in a total amount of at least 30 wt.% of the aerosolizable product. In one embodiment, glycerol is present in a total amount of at least 35 wt.% of the aerosolizable product.

[0031] In one embodiment, glycerol is present in a total amount of 5-40 wt.% of the aerosolizable product. In one embodiment, glycerol is present in a total amount of 10-40 wt.% of the aerosolizable product. In one embodiment, glycerol is present in a total amount of 15-40 wt.% of the aerosolizable product. In one embodiment, glycerol is present in a total amount of 20-40 wt.% of the aerosolizable product. In one embodiment, glycerol is present in a total amount of 25-40 wt.% of the aerosolizable product. In one embodiment, glycerol is present in a total amount of 30-40 wt.% of the aerosolizable product. In one embodiment, glycerol is present in a total amount of 35-40 wt.% of the aerosolizable product.

[0032] As discussed herein, in one embodiment, the aerosol-forming material is at least propylene glycol. The propylene glycol may be present in the aerosolizable product in any suitable amount. In one embodiment, the propylene glycol is present in a total amount of at least 5 wt.% of the aerosolizable product. In one embodiment, the propylene glycol is present in a total amount of at least 10 wt.% of the aerosolizable product. In one embodiment, the propylene glycol is present in a total amount of at least 15 wt.% of the aerosolizable product. In one embodiment, the propylene glycol is present in a total amount of at least 20 wt.% of the aerosolizable product. In one embodiment, the propylene glycol is present in a total amount of at least 25 wt.% of the aerosolizable product. In one embodiment, the propylene glycol is present in a total amount of at least 30 wt.% of the aerosolizable product. In one embodiment, the propylene glycol is present in a total amount of at least 35 wt.% of the aerosolizable product.

[0033] In one embodiment, propylene glycol is present in a total amount of 5-40 wt.% of the aerosolizable product. In one embodiment, propylene glycol is present in a total amount of 10-40 wt.% of the aerosolizable product. In one embodiment, propylene glycol is present in a total amount of 15-40 wt.% of the aerosolizable product. In one embodiment, propylene glycol is present in a total amount of 20-40 wt.% of the aerosolizable product. In one embodiment, propylene glycol is present in a total amount of 25-40 wt.% of the aerosolizable product. In one embodiment, propylene glycol is present in a total amount of 30-40 wt.% of the aerosolizable product. In one embodiment, propylene glycol is present in a total amount of 35-40 wt.% of the aerosolizable product.

[0034] smoke

[0035] As discussed herein, the aerosol-forming material is infused with smoke derived from plant material.

[0036] In one aspect, the plant material is selected from tobacco, wood, plant matter, cannabis, and combinations thereof.

[0037] In one aspect, the plant material is selected from tobacco, wood, and combinations thereof.

[0038] In one aspect, the plant material is at least wood. In one aspect, the plant material is only wood.

[0039] In one aspect, the plant material is at least tobacco. In one aspect, the plant material is exclusively tobacco.

[0040] In one aspect, the plant material is at least tobacco and wood. In one aspect, the plant material is exclusively tobacco and wood.

[0041] In one embodiment, the wood is selected from oak, cherry, hickory, beech, and combinations thereof.

[0042] The aerosol-forming material can be infused with smoke from one plant material or smoke from two or more plant materials. When the aerosol-forming material is infused with smoke from two or more plant materials, the infusions can be sequential or can be by combining the smokes and injecting the combined smoke into the aerosol-forming material.

[0043] In one aspect, the aerosol-forming material is infused with tobacco-derived smoke and wood-derived smoke. In one aspect, the aerosol-forming material is infused with tobacco-derived smoke and cherry wood-derived smoke. In one aspect, the aerosol-forming material is infused with tobacco-derived smoke and oak wood-derived smoke.

[0044] In one embodiment, the smoke is injected according to the method as described in WO 2015 / 007742.

[0045] Prior to injection of the smoke into the aerosol-forming material, the smoke may be treated between its formation and injection. However, in one embodiment, the smoke may remain untreated between its formation and injection. If the smoke is treated, the treatment may be to remove undesirable components. In one embodiment, the smoke is treated to selectively remove toxic substances. In one embodiment, the aerosol-forming material is injected with smoke that has been treated to selectively remove toxic substances. In one embodiment, the aerosol-forming material is injected with smoke that has been treated to selectively remove one or more aromatic hydrocarbons. In one embodiment, the aerosol-forming material is injected with smoke that has been treated to selectively remove benzene or its derivatives. In one embodiment, the aerosol-forming material is injected with smoke that has been treated to selectively remove toluene. In one embodiment, the aerosol-forming material is injected with smoke that has been treated to selectively remove phenol. In one embodiment, the aerosol-forming material is injected with smoke that has been treated to selectively remove one or more polycyclic aromatic hydrocarbons containing four or more benzene rings. In one embodiment, an aerosol-forming material is injected with smoke that has been treated to selectively remove benzo(a)pyrene. In one embodiment, an aerosol-forming material is injected with smoke that has been treated to selectively remove one or more toxic substances selected from toluene, phenol, and polycyclic aromatic hydrocarbons containing four or more benzene rings. In one embodiment, an aerosol-forming material is injected with smoke that has been treated to selectively remove one or more toxic substances selected from toluene, phenol, and benzo(a)pyrene. In one embodiment, an aerosol-forming material is injected with smoke that has been treated to selectively remove toluene and benzo(a)pyrene. In one embodiment, an aerosol-forming material is injected with smoke that has been treated to selectively remove toluene, phenol, and polycyclic aromatic hydrocarbons containing four or more benzene rings. In one embodiment, an aerosol-forming material is injected with smoke that has been treated to selectively remove toluene, phenol, and benzo(a)pyrene.

[0046] In one aspect, the smoke may be treated according to the method as described in WO 2015 / 007742.

[0047] Aerosolizable Products

[0048] The aerosolizable product of the present invention may contain one or more additional ingredients. These ingredients can be selected depending on the nature of the formulation. In one embodiment, the aerosolizable product further comprises an active agent. "Active agent" refers to an agent that has a biological effect on a subject when the vapor is inhaled. The one or more active agents can be selected from nicotine, botanicals, cannabinoids, and mixtures thereof.

[0049] In one embodiment, the active agent is at least nicotine. The nicotine may be provided in any suitable amount depending on the desired dose to be inhaled by the user. In one embodiment, the nicotine is present in an amount of 6 wt.% or less, based on the total weight of the aerosolizable product. In one embodiment, the nicotine is present in an amount of 0.4-6 wt.% based on the total weight of the aerosolizable product. In one embodiment, the nicotine is present in an amount of 0.8-6 wt.% based on the total weight of the aerosolizable product. In one embodiment, the nicotine is present in an amount of 1-6 wt.% based on the total weight of the aerosolizable product. In one embodiment, the nicotine is present in an amount of 1.8-6 wt.% based on the total weight of the aerosolizable product. In one embodiment, the nicotine is present in an amount of 0.4-5 wt.% based on the total weight of the aerosolizable product. In one embodiment, the nicotine is present in an amount of 0.8-5 wt.% based on the total weight of the aerosolizable product. In one embodiment, nicotine is present in an amount of 1-5 wt.% based on the total weight of the aerosolizable product. In one embodiment, nicotine is present in an amount of 1.8-5 wt.% based on the total weight of the aerosolizable product. In one embodiment, nicotine is present in an amount of 4 wt.% or less based on the total weight of the aerosolizable product. In one embodiment, nicotine is present in an amount of 0.4-4 wt.% based on the total weight of the aerosolizable product. In one embodiment, nicotine is present in an amount of 0.8-4 wt.% based on the total weight of the aerosolizable product. In one embodiment, nicotine is present in an amount of 1-4 wt.% based on the total weight of the aerosolizable product. In one embodiment, nicotine is present in an amount of 1.8-4 wt.% based on the total weight of the aerosolizable product. In one embodiment, nicotine is present in an amount of 3 wt.% or less based on the total weight of the aerosolizable product. In one embodiment, nicotine is present in an amount of 0.4-3 wt.% based on the total weight of the aerosolizable product. In one embodiment, nicotine is present in an amount of 0.8-3 wt.% based on the total weight of the aerosolizable product. In one embodiment, nicotine is present in an amount of 1-3 wt.% based on the total weight of the aerosolizable product. In one embodiment, nicotine is present in an amount of 1.8-3 wt.% based on the total weight of the aerosolizable product.In one embodiment, nicotine is present in an amount of 1.9 wt.% or less, based on the total weight of the aerosolizable product. In one embodiment, nicotine is present in an amount of 1.8 wt.% or less, based on the total weight of the aerosolizable product. In one embodiment, nicotine is present in an amount of 0.4-1.9 wt.% based on the total weight of the aerosolizable product. In one embodiment, nicotine is present in an amount of 0.4-1.8 wt.% based on the total weight of the aerosolizable product. In one embodiment, nicotine is present in an amount of 0.5-1.9 wt.% based on the total weight of the aerosolizable product. In one embodiment, nicotine is present in an amount of 0.5-1.8 wt.% based on the total weight of the aerosolizable product. In one embodiment, nicotine is present in an amount of 0.8-1.9 wt.% based on the total weight of the aerosolizable product. In one embodiment, nicotine is present in an amount of 0.8-1.8 wt.% based on the total weight of the aerosolizable product. In one embodiment, nicotine is present in an amount of 1-1.9 wt.% based on the total weight of the aerosolizable product. In one embodiment, nicotine is present in an amount of 1-1.8 wt.% based on the total weight of the aerosolizable product. In one embodiment, nicotine is present in an amount less than 1.9 wt.% based on the total weight of the aerosolizable product. In one embodiment, nicotine is present in an amount less than 1.8 wt.% based on the total weight of the aerosolizable product. In one embodiment, nicotine is present in an amount of 0.4-1.9 wt.% based on the total weight of the aerosolizable product. In one embodiment, nicotine is present in an amount of 0.4-1.8 wt.% based on the total weight of the aerosolizable product. In one embodiment, nicotine is present in an amount of 0.5-1.9 wt.% based on the total weight of the aerosolizable product. In one embodiment, nicotine is present in an amount of 0.5-1.8 wt.% based on the total weight of the aerosolizable product. In one embodiment, nicotine is present in an amount of 0.8 to less than 1.9 wt.% based on the total weight of the aerosolizable product. In one embodiment, nicotine is present in an amount of 0.8 to less than 1.8 wt.% based on the total weight of the aerosolizable product. In one embodiment, nicotine is present in an amount of 1 to less than 1.9 wt.% based on the total weight of the aerosolizable product.In one embodiment, the nicotine is present in an amount of less than 1-1.8 wt.% based on the total weight of the aerosolizable product.

[0050] The aerosol formed from the aerosolizable product can have a pH of 3.5 to 7.5.

[0051] method

[0052] The present invention provides a method for forming a vapor, comprising: (a) providing an aerosolizable product including an aerosol-forming material, wherein tobacco-derived smoke is infused into the aerosol-forming material; (b) vaporizing the aerosolizable product; The present invention further provides a method comprising:

[0053] The present invention provides a method for forming a vapor, comprising: (a) providing an aerosolizable product comprising an aerosol-forming material, the aerosol-forming material being selected from glycerol, propylene glycol, and mixtures thereof, and wherein smoke derived from a plant material is infused into the aerosol-forming material; (b) vaporizing the aerosolizable product; The present invention further provides a method comprising:

[0054] The present invention provides a method for improving the sensory properties of an aerosolizable product, comprising: (a) providing an aerosol-forming material; (b) injecting tobacco smoke into the aerosol-forming material; The present invention further provides a method comprising:

[0055] The present invention provides a method for improving the sensory properties of an aerosolizable product, comprising: (a) providing an aerosol-forming material selected from glycerol, propylene glycol, and mixtures thereof; (b) injecting smoke from plant material into the aerosol-forming material; The present invention further provides a method comprising:

[0056] Further Aspects

[0057] The aerosolizable product may be contained or delivered by any means. In one aspect, the present invention provides a method for administering aerosolizable products comprising: (a) a container; (b) an aerosolizable product containing an aerosol-forming material, wherein the aerosol-forming material is infused with tobacco-derived smoke; The present invention provides an aerosolizable product in a container comprising:

[0058] In a further aspect, the present invention provides a method for producing a pharmaceutical composition comprising: (a) a container; (b) an aerosolizable product comprising an aerosol-forming material, the aerosol-forming material being selected from glycerol, propylene glycol, and mixtures thereof, and the aerosol-forming material being infused with smoke derived from a plant material; and The present invention provides an aerosolizable product in a container comprising:

[0059] The container may be, for example, any suitable container that allows for the storage or delivery of an aerosolizable product. In one aspect, the container is configured to engage an electronic vapor delivery system. The container may be configured to be in fluid communication with an electronic vapor delivery system such that the aerosolizable product can be delivered to the electronic vapor delivery system. As noted above, the present disclosure relates to containers that can be used in electronic vapor delivery systems, such as e-cigarettes. Throughout the following description, the term "e-cigarette" is used; however, this term can be used interchangeably with electronic vapor delivery system.

[0060] As discussed herein, the container of the present invention is typically provided for delivering an aerosolizable product to or within an e-cigarette. The aerosolizable product may be retained within the e-cigarette or may be sold as a separate container for subsequent use with or within the e-cigarette. As will be understood by those skilled in the art, an e-cigarette may contain a unit known as a removable cartomizer, which typically comprises an aerosolizable product reservoir, a wick material, and a device for vaporizing the aerosolizable product. In some e-cigarettes, the cartomizer is part of a single-piece device and is not removable. In one aspect, the container is the cartomizer or part of the cartomizer. In one aspect, the container is not a cartomizer or part of a cartomizer, but rather a container, such as a tank, that can be used to deliver an aerosolizable product to or within the e-cigarette.

[0061] In one aspect, the container is part of an e-cigarette. (a) a vaporizer for converting a liquid into a vapor for inhalation by a user of the electronic vapor delivery system; (b) a power source, including a cell or battery, for powering the vaporizer; (c) an aerosolizable product containing an aerosol-forming material, wherein the aerosol-forming material is infused with tobacco-derived smoke; There is further provided an electronic vapor delivery system including:

[0062] In a further aspect, the present invention provides a method for producing a pharmaceutical composition comprising: (a) a vaporizer for converting a liquid into a vapor for inhalation by a user of the electronic vapor delivery system; (b) a power source, including a cell or battery, for powering the vaporizer; (c) an aerosolizable product comprising an aerosol-forming material, the aerosol-forming material being selected from glycerol, propylene glycol, and mixtures thereof, and the aerosol-forming material being infused with smoke derived from a plant material; and There is further provided an electronic vapor delivery system including:

[0063] The methods of the present invention may include additional steps either before the listed steps, after the listed steps, or between one or more of the listed steps.

[0064] In addition to the aerosolizable products of the present invention and systems, such as containers and electronic aerosol delivery systems, containing same, the present invention provides for the use of smoke to improve the sensory properties of aerosol-forming materials.

[0065] The invention will now be described with reference to the following non-limiting examples. [Example]

[0066] compound

[0067] To prepare the flavoring liquid, 500 g of tobacco (Virginia) was smoked with 500 g of selected wood (oak) for a total of 4 hours. The resulting smoke was then divided into two samples. One sample was filtered according to the method described in WO 2015 / 007742, while the other sample was not filtered. The smoke sample was then exposed to a selected aerosolizable material (propylene glycol).

[0068] Sample A was a sample processed according to WO 2015 / 007742. Sample B was a sample that did not go through a filtration step before exposure to the aerosolizable material (propylene glycol).

[0069] Sample analysis

[0070] A series of analytical tests were required to quantify the compounds of interest. The liquid was tested for nicotine, water, glycerol, N-nitrosonornicotine (NNN), N'-nitrosoanatabine (NAT), N-nitrosoanabasine (NAB), nicotine-derived nitrosamine ketone (NNK, also known as 4-(methylnitrosamino)-1-(3-pyridyl)-1-butanone), benzo(a)pyrene, toluene, phenol, and propylene glycol. The aerosol was tested for formaldehyde, acetaldehyde, acetone, propionaldehyde, isobutyraldehyde, methyl ethyl ketone, acetol, glyoxal, methylglyoxal, 2,3-butanedione, acrolein, n-butyraldehyde, crotonaldehyde, glycolaldehyde, acetoin, 2,3-pentanedione, 2,3-hexanedione, and 2,3-heptanedione.

[0071] For emissions testing, the following formulation matrix was used to fill Vype e-Tank devices, which were tested for the presence and levels of the carbonyls listed in 1 above.

[0072] Vegetable glycerol 47% w / w Propylene glycol (treated smoke) 35% w / w Water 18% w / w

[0073] The devices containing Samples A and B were then blown in a linear smoke machine using an 80 / 3 / 30 regime. A total of 100 blows were taken, captured in 25 blow blocks for both samples. The resulting average was 3 reps per blow block.

[0074] Liquid Test

[0075] The following analytes were not detected in either sample solution (A or B): Nicotine, glycerol, NNN, NAT, NAB and NNK.

[0076] The following is also noted: Sample A - Sample B: Benzo(a)pyrene ( <LOD) Toluene ( <LOD) Sample A - significantly lower phenol levels compared to Sample B

[0077] Aerosol Testing

[0078] The following analytes were not detected in the aerosols formed from either sample (A or B): Acrolein, n-butyraldehyde, crotonaldehyde, glycolaldehyde, acetoin, 2,3-pentanedione, 2,3-hexanedione and 2,3-heptanedione.

[0079] User Test

[0080] Each of Samples A and B is tested by a user panel and found to provide a pleasant experience. Each of Samples A and B is found to provide an aerosol with enhanced flavor and aroma compared to the unsmoked product.

[0081] Various modifications and variations of the present invention will be apparent to those skilled in the art without departing from the scope and spirit of the invention. Although the invention has been described in connection with specific preferred embodiments, it should be understood that the invention as claimed should not be unduly limited to such specific embodiments. Indeed, various modifications of the described modes for carrying out the invention that are obvious to those skilled in chemistry or related fields are intended to be within the scope of the following claims.

Claims

1. 1. An aerosolizable product comprising an aerosol-forming material, wherein the aerosol-forming material is infused with tobacco-derived smoke, the smoke being treated to selectively remove toxic substances.

2. 10. The aerosolizable product of claim 1, wherein the smoke is treated between its formation and injection.

3. 3. The aerosolizable product of claim 1 or 2, wherein the aerosol-forming material is selected from polyhydric alcohols, esters, high-boiling hydrocarbons, non-polyols, and mixtures thereof.

4. 4. The aerosolizable product of claim 3, wherein the polyhydric alcohol is selected from glycerol, propylene glycol, and triethylene glycol, the ester is selected from triethyl citrate and triacetin, and the non-polyol is selected from glycol, sorbitol, and lactic acid.

5. 5. The aerosolizable product of any one of claims 1 to 4, further comprising nicotine.

6. 6. The aerosolizable product of claim 5, comprising nicotine in an amount of 2 wt. % or less, based on the total weight of the aerosolizable product.

7. 6. The aerosolizable product of claim 5, comprising nicotine in an amount of 1.8 wt.% or less, based on the total weight of the aerosolizable product.

8. 8. The aerosolizable product of any one of claims 1 to 7, further comprising water.

9. 9. An aerosolizable product according to any one of claims 1 to 8, wherein the aerosol-forming material is infused with smoke that has been treated to selectively remove benzene or its derivatives.

10. 10. The aerosolizable product of claim 9, wherein the aerosol-forming material is infused with smoke that has been treated to selectively remove toluene.

11. 9. The aerosolizable product of any one of claims 1 to 8, wherein the aerosol-forming material is infused with smoke that has been treated to selectively remove one or more polycyclic aromatic hydrocarbons containing four or more benzene rings.

12. 12. The aerosolizable product of claim 11, wherein the aerosol-forming material is infused with smoke that has been treated to selectively remove benzo(a)pyrene.

13. 9. The aerosolizable product of any one of claims 1 to 8, wherein the aerosol-forming material is infused with smoke that has been treated to selectively remove toluene and benzo(a)pyrene.

14. 14. The aerosolizable product of any one of claims 1 to 13, wherein the aerosol formed from the aerosolizable product has a pH of 3.5 to 7.

5.

15. 15. An aerosolizable product according to any one of claims 1 to 14, wherein the aerosol-forming material is selected from glycerol, propylene glycol and mixtures thereof.

16. 16. The aerosolizable product of any one of claims 1 to 15, wherein the aerosol-forming material is present in an amount of at least 5 wt. %, based on the total weight of the aerosolizable product.

17. (a) a container; (b) an aerosolizable product according to any one of claims 1 to 16; Aerosolizable products in containers containing:

18. 20. The packaged aerosolizable product of claim 17, wherein the container is configured to engage an electronic aerosol delivery system.

19. 20. The packaged aerosolizable product of claim 18, wherein the electronic aerosol delivery system is an electronic vapor delivery system.

20. 20. The packaged aerosolizable product of claim 18, wherein the container is a cartomizer or part of a cartomizer.

21. 21. The packaged aerosolizable product of claim 20, wherein the cartomizer comprises a wicking material and a device for vaporizing the aerosolizable product.

22. 21. The packaged aerosolizable product of claim 20, wherein the cartomizer is a removable cartomizer.

23. 21. The packaged aerosolizable product of claim 20, wherein the cartomizer is part of a single-piece device.

24. (i) an aerosolization device for aerosolizing an aerosolizable product for inhalation by a user of the electronic aerosol delivery system; (ii) a power source including a cell or battery for powering the aerosolization device; (iii) an aerosolizable product according to any one of claims 1 to 16; 1. An electronic aerosol delivery system comprising:

25. (a) a vaporizer for converting a liquid into a vapor for inhalation by a user of the electronic vapor delivery system; (b) a power source including a cell or battery for powering the vaporizer; (c) an aerosolizable product according to any one of claims 1 to 16; Electronic vapor delivery system including:

26. 1. A method for improving the sensory properties of an aerosolizable product, comprising: (a) providing an aerosol-forming material; (b) injecting tobacco-derived smoke into the aerosol-forming material; wherein the smoke has been treated to selectively remove toxic substances.

27. The method of claim 26, wherein the aerosolizable product is according to any one of claims 2 to 16.

28. 1. Use of smoke to improve the sensory properties of an aerosol-forming material, wherein the aerosol-forming material is infused with tobacco-derived smoke, the smoke having been treated to selectively remove toxic substances.