Functional articles, methods for confirming active ingredients, and coating liquids.

Abstract

The present invention provides a functional article and an active ingredient confirmation method whereby the presence or absence of an action by the active ingredient adhered on a base material can be accurately confirmed. A functional product according to the present invention is a functional article including a base material and an adhering body of an action composition which is adhered to the base material and contains an active ingredient and a light-emitting substance. The functional product is characterized in that if at least an effective usage amount of the active ingredient adhered to the base material is present, the luminance of the surface of the functional article is changed by radiation light radiated from the light-emitting substance due to the adhering body of the action composition being illuminated with ultraviolet rays of the UVA range.

Description

[Technical Field]

[0001] This invention relates to functional articles, methods for identifying active ingredients, and coating liquids. [Background technology]

[0002] In recent years, in addition to seasonal influenza virus outbreaks, the novel coronavirus (COVID-19) has become a global pandemic.

[0003] With highly pathogenic avian influenza viruses mutating and showing signs of transmission between humans, and with concerns also rising about the extremely lethal SARS virus, anxiety about viruses is only increasing.

[0004] In addition to inhaling viruses contained in saliva, it is known that viral infections can also occur when hands come into contact with objects contaminated with the virus, and then these hands are used to eat food or touch mucous membranes such as the eyes or mouth.

[0005] To reduce viral infections through such transmission routes, antiviral agents are applied to the surfaces of items that people may come into contact with, so that when a virus adheres to an item, its viral activity is inactivated by the antiviral agent.

[0006] On the other hand, while antiviral agents applied to the surface of an object are usually made colorless and transparent so as not to impair the appearance of the object, as mentioned above, because they are applied to places that people may come into contact with, the antiviral agent applied to the surface of the object may decrease over time due to friction when people come into contact with it, or by dissolving in the moisture and oil present on the surface of people's hands, and there is a risk that the antiviral agent may not maintain its antiviral properties.

[0007] Therefore, Patent Document 1 discloses an antimicrobial composition comprising about 10% to about 75% by weight of at least one acid, at least one sulfonate, sulfate and / or carboxylate anionic surfactant, and water, wherein the composition is a dilutable liquid concentrate having an acidic pH that is nonflammable, and the composition is disclosed to contain a fluorescent substance. [Prior art documents] [Patent Documents]

[0008] [Patent Document 1] Special Publication No. 2020-535155 [Overview of the Initiative] [Problems that the invention aims to solve]

[0009] However, even if a fluorescent substance is included in the composition, if there is a difference in the rate of decrease over time due to contact with hands, etc., between the active ingredient that exhibits antibacterial properties in the composition and the fluorescent substance, there is a problem that the user may mistakenly perceive the presence of the active ingredient due to the fluorescence of the fluorescent substance used as an indicator, even though the active ingredient has disappeared.

[0010] The present invention provides a functional article and a method for confirming the active ingredient that can confirm that the effective effect of the active ingredient attached to the substrate has been lost or that the time of loss of the effective effect is approaching.

[0011] The present invention provides a coating liquid that can be used to manufacture functional articles by coating it onto a substrate. [Means for solving the problem]

[0012] The functional product of the present invention is Substrate and A functional article comprising an attachment of an active composition containing an active ingredient and a luminescent substance, which is attached to the above-mentioned substrate, When the content of the active ingredient adhered to the above-mentioned substrate is less than the effective usage amount, the brightness change of the surface of the above-mentioned functional article due to the radiation light emitted from the above-mentioned luminescent substance is lost by irradiating the adherent of the above-mentioned action composition with ultraviolet rays in the UVA region.

[0013] The method for confirming the active ingredient of the present invention is It includes a substrate and an adherent of an action composition containing an active ingredient and a luminescent substance adhered to the above-mentioned substrate. When the content of the active ingredient adhered to the above-mentioned substrate is less than the effective usage amount, the adherent of the above-mentioned action composition is irradiated with ultraviolet rays in the UVA region, and the brightness change of the surface of the above-mentioned functional article due to the radiation light emitted from the above-mentioned luminescent substance is lost. An ultraviolet irradiation step of irradiating the adherent of the above-mentioned action composition of the functional article with ultraviolet rays in the UVA region; Confirming the brightness change of the surface of the above-mentioned functional article irradiated with the ultraviolet rays in the UVA region, and when the brightness of the surface of the above-mentioned functional article changes, including a confirmation step of confirming that the content of the above-mentioned active ingredient is not less than the effective usage amount.

[0014] The coating liquid of the present invention is It contains an action composition containing an active ingredient and a luminescent substance, The adherent of the above-mentioned action composition can be formed on a substrate, When the content of the active ingredient in the above-mentioned adherent is less than the effective usage amount, the adherent of the above-mentioned action composition is irradiated with ultraviolet rays in the UVA region, and the brightness change of the surface of the above-mentioned substrate on which the above-mentioned adherent is formed due to the radiation light emitted from the above-mentioned luminescent substance is lost. It is characterized by being configured as such.

Effect of the Invention

[0015] When the content of the active ingredient in the functional article of the present invention is not less than the effective usage amount or exists in excess of the effective usage amount, by irradiating the action composition containing the active ingredient and the luminescent substance with ultraviolet rays in the UVA region, radiation light can be emitted from the luminescent substance to change the brightness of the surface of the functional article.

[0016] On the other hand, in the functional article of the present invention, if the content of the active ingredient is less than the effective usage amount, even if the working composition containing the active ingredient and the luminescent substance is irradiated with ultraviolet light in the UVA range, the brightness change on the surface of the functional article due to synchrotron radiation emitted from the luminescent substance is lost.

[0017] Therefore, according to the functional article of the present invention, when ultraviolet light in the UVA range is irradiated onto the adhering active composition on the substrate surface of the functional article, and the change in brightness of the surface of the functional article is lost (no change in brightness), the content of the active ingredient is at or near the effective usage amount. In other words, it is easy to confirm that the effective effect of the active ingredient has been lost in the functional article, or that the time when the effective effect of the active ingredient will be lost is approaching.

[0018] According to the paint of the present invention, the above-mentioned functional article can be easily manufactured by coating it onto the surface of a substrate and forming an adhesion of the active composition on the substrate surface. [Modes for carrying out the invention]

[0019] The functional article of the present invention comprises a base material and an attachment body which adheres to the base material and contains an active composition comprising an active ingredient and a luminescent substance.

[0020] The base material constituting the functional article is not particularly limited as long as it is something that people come into contact with, on which harmful substances such as viruses, bacteria, and allergens may adhere, and on which the active composition can be applied. Examples include building components such as doorknobs and sliding doors, furniture such as chairs, desks, and closets, building interior materials, synthetic resin molded products, paints, wallpaper, decorative sheets, flooring materials, textile products (woven fabrics, nonwoven fabrics, knitted fabrics), interior accessories and interior materials for vehicles (e.g., cars, airplanes, ships, etc.) (seats, child seats, and the foams that make them up, etc.), kitchenware, baby products, and the like.

[0021] The active composition adheres to the surface of the substrate as an adsorbent. The active composition contains an active ingredient and a luminescent substance.

[0022] The active ingredient is not particularly limited as long as it is a compound that exhibits a predetermined effect such as antiviral, antibacterial, or anti-allergenic properties. The active ingredient may be used alone or in combination of two or more.

[0023] Examples of active ingredients in antiviral agents include water-soluble compounds such as sulfonic acid compounds, carboxylic acid compounds (e.g., polyacrylic acid, sodium polyacrylate, etc.), dimethyloctadecyl-3-trimethoxysilylpropylammonium chloride, and non-water-soluble compounds such as zincpyridione 2-(4-thiazolyl)-benzimidazole, 10,10-oxybisphenoxanodine, organic nitrogen-sulfur halogens, and pyridine-2-thiol oxide, with water-soluble compounds being preferred. Among these, the active ingredient of the antiviral agent is preferably a sulfonic acid compound or a carboxylic acid compound, and more preferably a sulfonic acid compound, because it exhibits excellent antiviral activity.

[0024] In the present invention, a water-soluble compound refers to a compound whose solubility in 10 g of a mixed medium containing 40% by mass of ethanol and 60% by mass of water at 1 atmosphere and 25°C is 0.01 g / 10 g or more.

[0025] The amount of active ingredient dissolved in 10 g of a mixed medium containing 40% by mass of ethanol and 60% by mass of water at 1 atmosphere and 25°C can be measured, for example, by the following procedure: Prepare a mixture by adding 0.1 g of the active ingredient to 10 g of a mixed medium containing 40% by mass of ethanol and 60% by mass of water. Stir the mixture with a stirrer for 1 hour at 25°C and 1 atmosphere. Next, filter 1 mL of the mixture through a polytetrafluoroethylene (PTFE) filter with a pore size of 0.2 μm to obtain a filtrate. After measuring the mass (g) of the filtrate, quantify the amount of active ingredient in the filtrate by high-performance liquid chromatography (HPLC) and calculate the amount of active ingredient dissolved per 10 g of mixed medium. For example, in the case of the antiviral agent sodium dodecylbenzenesulfonate, the HPLC conditions are as follows: Prepare a standard by dissolving sodium dodecylbenzenesulfonate in pure water to a concentration of 0.1 g / 10 g. Calculate the concentration of the active ingredient in the filtrate from a calibration curve created using the standard. Column: Shodex brand, product name "Asahipak GF-310HQ" Column size: 7.5 x 300 mm Mobile phase: 50% by volume acetonitrile, 50% by volume 50 mM sodium chloride aqueous solution Flow rate: 0.6mL / min Column temperature: 40℃ Detection wavelength: 254nm

[0026] The above-mentioned sulfonic acid compounds have a sulfonic acid group (-SO3H) and / or a sulfonic acid group derivative (hereinafter, the sulfonic acid group and the sulfonic acid group derivative may be collectively referred to as the "sulfonic acid-derived group") in their molecules. The sulfonic acid compounds exert their viral infection-inhibiting effect from the molecular structural portion containing the sulfonic acid group (-SO3H) and / or the sulfonic acid group derivative.

[0027] The sulfonic acid group derivative is not particularly limited and includes, for example, salts of the sulfonic acid group, esterified products such as -SO3CH3 and -SO3C2H5, with salts of the sulfonic acid group being preferred.

[0028] The salt of the sulfonic acid group is not particularly limited, and examples include sodium sulfonate salt, calcium sulfonate salt, ammonium sulfonate salt, magnesium sulfonate salt, and barium sulfonate salt, with sodium sulfonate salt being preferred.

[0029] The sulfonic acid compound is preferably an organic compound. In the present invention, an organic compound is defined as a compound that contains at least one (preferably two or more) carbon atoms in its molecule and contains a carbon-hydrogen bond (CH bond).

[0030] Sulfonic acid compounds are not particularly limited as long as they have either or both a sulfonic acid group and / or a sulfonic acid derivative in their molecule. Examples include linear alkylbenzene sulfonic acid, linear alkylbenzene sulfonate, α-olefin sulfonic acid, alkyl diphenyl ether sulfonic acid, alkyl diphenyl ether sulfonate, α-olefin sulfonate, polyoxyalkylene alkyl ether sulfate salt, and polymers having sulfonic acid-derived groups in the side chains of linear polymers.

[0031] Examples of linear alkylbenzenesulfonic acids include dodecylbenzenesulfonic acid, decylbenzenesulfonic acid, undecylbenzenesulfonic acid, tridecylbenzenesulfonic acid, and tetradecylbenzenesulfonic acid.

[0032] Examples of linear alkylbenzene sulfonates include sodium dodecylbenzenesulfonate, calcium dodecylbenzenesulfonate, ammonium dodecylbenzenesulfonate, magnesium dodecylbenzenesulfonate, barium dodecylbenzenesulfonate, sodium decylbenzenesulfonate, ammonium decylbenzenesulfonate, sodium undecylbenzenesulfonate, ammonium decylbenzenesulfonate, sodium undecylbenzenesulfonate, ammonium undecylbenzenesulfonate, sodium tridecylbenzenesulfonate, ammonium tridecylbenzenesulfonate, sodium tetradecylbenzenesulfonate, and ammonium tetradecylbenzenesulfonate, with sodium dodecylbenzenesulfonate being preferred.

[0033] In polymers having sulfonic acid-derived groups in the side chains of linear polymers, the linear polymer is not particularly limited, but is preferably vinyl polymer, polyester, or polyurethane, with vinyl polymer being preferred.

[0034] Polymers having sulfonic acid-derived groups in the side chains of linear polymers are not particularly limited, and examples include polymers containing styrene sulfonic acid components, polymers containing styrene sulfonic acid derivative components, sulfonic acid derivatives of polymers containing styrene sulfonic acid components, copolymers containing styrene sulfonate components and styrene sulfonic acid derivative components, styrene sulfonic acid homopolymers, styrene sulfonate homopolymers, styrene sulfonic acid derivative homopolymers, styrene-styrene sulfonate copolymers, styrene-styrene sulfonic acid copolymers, compounds in which the benzene ring of polystyrene is sulfonated, sulfonic acid derivatives of compounds in which the benzene ring of polystyrene is sulfonated, compounds in which the benzene ring of a polymer containing a styrene component is sulfonated, and sulfonic acid derivatives of compounds in which the benzene ring of a polymer containing a styrene component is sulfonated.

[0035] Furthermore, polymers having sulfonic acid-derived groups in the side chains of linear polymers are preferably homopolymers or copolymers of monomers having sulfonic acid-derived groups. Examples of monomers having sulfonic acid-derived groups include p-styrenesulfonic acid, m-styrenesulfonic acid, o-styrenesulfonic acid, sodium p-styrenesulfonate, sodium m-styrenesulfonate, sodium o-styrenesulfonate, calcium p-styrenesulfonate, calcium m-styrenesulfonate, calcium o-styrenesulfonate, ammonium p-styrenesulfonate, ammonium m-styrenesulfonate, ammonium o-styrenesulfonate, ethyl p-styrenesulfonate, ethyl m-styrenesulfonate, ethyl o-styrenesulfonate, 4-vinylbenzoic acid, sodium 4-vinylbenzoate, methyl 4-vinylbenzoate, 4-vinylaniline, aminostyrene hydrochloride, N-acetylaminostyrene, N-benzoylaminostyrene, naphthalenesulfonic acid, sodium naphthalenesulfonate, calcium naphthalenesulfonate, etc. Sodium styrenesulfonate is preferred, and sodium p-styrenesulfonate is more preferred because it exhibits less steric hindrance in reactivity with viruses.

[0036] Monomers having sulfonic acid-derived groups may form copolymers with other monomers. Examples of copolymerizable monomers include alkyl acrylates, alkyl methacrylates, vinyl alkyl ethers, vinyl acetate, ethylene, propylene, butylene, butadiene, diisobutylene, vinyl chloride, vinylidene chloride, 2-vinylnaphthalene, styrene, acrylonitrile, acrylic acid, sodium acrylate, methacrylic acid, maleic acid, fumaric acid, maleic anhydride, acrylamide, methacrylamide, diacetone acrylamide, vinyltoluene, xylene sulfonic acid, vinylpyridine, vinyl sulfonic acid, vinyl alcohol, methyl methacrylate, sodium methacrylate, and hydroxyethyl methacrylate, but styrene is preferred.

[0037] Polymers having sulfonic acid-derived groups in the side chains of linear polymers can be produced by general methods, such as radical polymerization of monomers having sulfonic acid-derived groups, radical polymerization of monomers having sulfonic acid-derived groups and monomers copolymerizable with this monomer, and neutralization of the sulfonic acid in a polymer containing a monomer component having sulfonic acid-derived groups using an alkali such as sodium hydroxide, calcium hydroxide, potassium hydroxide, or ammonium hydroxide.

[0038] Examples of active ingredients in antibacterial agents include quaternary ammonium salts such as tetramethylammonium chloride, tetraethylammonium chloride, tetramethylammonium hydroxide, and tetraethylammonium hydroxide; phenolic compounds such as 3-methyl-4-isopropylphenol and ortho-phenylphenol; benzothiazoles such as 5-chloro-2-methyl-4-isothiazolin-3-one and 2-mercaptobenzothiazole; and isothiazolines such as 2-n-octyl-4-isothiazolin-3-one and 5-chloro-2-methyl-4-isothiazolin-3-one.

[0039] Examples of active ingredients in anti-allergen agents include aromatic hydroxy compounds such as tannic acid and polyvinylphenol, and the sulfonic acid compounds mentioned above. Among these, aromatic hydroxy compounds are preferred, and polyvinylphenol is more preferred, due to their excellent allergen-reducing effect.

[0040] As aromatic hydroxy compounds, compounds containing at least one structure shown in formulas (1) to (6) are preferred. In formulas (1) to (6), * represents a bond that is a single bond.

[0041] [ka]

[0042] In equations (1) to (6), each of the multiple Rs is either a hydrogen atom or a hydroxyl group (-OH), and at least one of them represents a hydroxyl group. n is an integer from 0 to 5.

[0043] Aromatic hydroxy compounds are preferably compounds having at least one structure shown in formulas (1) to (6) in the side chain of the linear polymer. Examples of linear polymers include vinyl polymers, polyesters, and polyamides.

[0044] The chemical bond between at least one structure represented by formulas (1) to (6) and the linear polymer is not particularly limited and includes carbon-carbon bonds, ester bonds, ether bonds, amide bonds, and the like.

[0045] Compounds having at least one structure represented by formulas (1) to (6) in the side chain of a linear polymer are not particularly limited, and examples include poly(3,4,5-hydroxybenzoate vinyl), polyvinylphenol, polytyrosine, poly(1-vinyl-5-hydroxynaphthalene), poly(1-vinyl-6-hydroxynaphthalene), and poly(1-vinyl-5-hydroxyanthracene).

[0046] The position of the hydroxyl group (-OH) in polyvinylphenol is not particularly limited. Poly(p-vinylphenol) is preferred because it has excellent allergen-reducing effects.

[0047] Aromatic hydroxy compounds can be produced by polymerizing or copolymerizing a monomer composition containing monomers having at least one structure represented by formulas (1) to (6). Examples of monomers copolymerizable with monomers having at least one structure represented by formulas (1) to (6) include ethylene, acrylate, methacrylate, methyl methacrylate, hydroxyethyl methacrylate, hydroxyethyl acrylate, hydroxypropyl acrylate, hydroxypropyl methacrylate, and styrene.

[0048] Polyvinylphenol can be produced by radical polymerization of vinylphenol using a general procedure. Polyvinylphenol refers to a polymer of vinylphenol from which the vinylphenol oligomer has been removed. In other words, polyvinylphenol refers to a polymer of vinylphenol with a degree of polymerization of 6 or higher.

[0049] Here, an anti-allergen agent refers to a substance that has an allergen-reducing effect. "Allergen-reducing effect" refers to the effect of denaturing or adsorbing allergens such as dust mite allergens (Der1, Der2), airborne cedar pollen allergens (Cryj1, Cryj2), and allergens caused by dogs and cats (Can f1, Fel d1), thereby reducing the reactivity of the allergen to specific antibodies. Methods for confirming such an allergen-reducing effect include, for example, measuring the amount of allergen by ELISA using an ELISA kit commercially available from Nichinichi Pharmaceutical Co., Ltd., and evaluating allergenicity using an allergen measuring device (product name "Mighty Checker" manufactured by Sumika Enviroscience Co., Ltd.).

[0050] Examples of active ingredients in deodorants include cyclodextrin compounds, betaine compounds, plant extracts, and seaweed extracts.

[0051] The active ingredient contains a luminescent substance. A luminescent substance is a compound that, when irradiated with ultraviolet light in the UVA region (330-385 nm), produces synchrotron radiation (e.g., fluorescence, phosphorescence, etc.) with wavelengths in the visible light region (420-800 nm). Examples of luminescent substances include fluorescent substances and phosphorescent substances. Fluorescence refers to the light emitted when transitioning from an excited singlet state to the ground state. Phosphorescence refers to the light emitted when transitioning from an excited triplet state to the ground state, and industrially, luminescent materials that utilize this phenomenon are widely used as phosphorescent materials.

[0052] The fluorescent substance is not particularly limited as long as it is a compound that produces fluorescence when irradiated with ultraviolet light in the UVA range. Examples of fluorescent substances include fluorescent whitening agents, methylene blue, Nile blue, anthraquinone derivatives, naphthalene derivatives, metal ammine complexes, and compounds with redox activity such as metal complexes containing organic ligands such as bipyridine derivatives, phenanthroline derivatives, and dipyridofenadine derivatives. Fluorescent whitening agents are preferred because their reduction rate is similar to that of the active ingredient.

[0053] The fluorescent whitening agent is not particularly limited, and examples include diaminostilbene type fluorescent whitening agents such as fluorescent 260, bisstyrylbiphenyl type fluorescent whitening agents such as fluorescent 351, fluorescent 134, fluorescent 90, and fluorescent 213. Preferably, the fluorescent whitening agent is one or more fluorescent whitening agents selected from the group consisting of fluorescent 134, fluorescent 90, and fluorescent 213.

[0054] Commercially available fluorescent substances can be used. Examples of such fluorescent substances include "Special Phosphor No. 490-E" (Fluorescent 90) from Nippon Fluorescent Chemicals Co., Ltd., and "LeuchMarker R-70," "LeuchMarker R-50," and "LeuchMarker MR-30" from Shinloihi Co., Ltd.

[0055] The phosphorescent material can be a commercially available product. Examples of phosphorescent materials include phosphorescent pigments such as zinc oxide-zinc systems, zinc silicate-manganese systems, yttrium oxide-europium systems, zinc sulfide-manganese systems, zinc sulfide-copper systems, samarium, iridium, and organic complexes of europium.

[0056] The active composition is attached to the substrate (surface of the substrate) as an adhesive, and when the amount of active ingredients contained in this active composition is greater than or equal to the effective usage amount described later, or exceeds the effective usage amount (preferably 1.2 times or more the effective usage amount), the brightness of the surface of the functional article is configured to change due to the synchrotron radiation emitted from the light-emitting substance in the active composition.

[0057] On the other hand, if the amount of active ingredient contained in the active composition attached to the substrate is less than the effective usage amount, the system is configured so that no change in the brightness of the surface of the functional article occurs due to the synchrotron radiation emitted from the light-emitting substance in the active composition.

[0058] In other words, in an attachment of a functional composition formed on a functional article, if the amount of active ingredients contained in the functional composition is equal to or greater than the effective usage amount (preferably 1.2 times or more the effective usage amount), the composition is configured such that the amount of luminescent material contained in the functional article is equal to or greater than the standard content described later, which is the amount by which the brightness of the surface of the functional article changes due to the synchrotron light emitted from the luminescent material in the functional composition.

[0059] On the other hand, if the amount of active ingredients contained in the active composition attached to the substrate decreases over time with use and falls below the effective usage amount, the amount of luminescent substance in the active composition will be below the standard amount, and the composition is configured so that the brightness of the surface of the functional article does not change due to the synchrotron radiation emitted from the luminescent substance in the active composition.

[0060] In detail, the functional article has an adsorbent of the active composition on the surface of the base material, and is configured to exhibit a desired effect (effective action) through the active ingredients contained in this adsorbent of the active composition.

[0061] The surface of a functional article comes into contact with human hands, clothing, and other objects. The frictional force resulting from such contact gradually removes the active composition adhering to the surface of the base material. Additionally, the active composition dissolves in the moisture and oil contained in human hands, further gradually removing it from the base material surface. Therefore, the amount of active composition adhering to the surface of a functional article decreases over time with use.

[0062] On the other hand, the adhering bodies of the active composition formed on the surface of functional articles are usually made colorless and transparent so as not to impair the appearance of the substrate, making it difficult to confirm under normal use conditions whether the active composition is present on the substrate in a way that allows the active ingredients to exert the desired effect.

[0063] Therefore, the above-mentioned functional article contains a light-emitting substance along with the active ingredient in the active composition, and is configured so that it is possible to confirm whether or not the amount of active ingredient has fallen below the effective usage amount based on the change in brightness of the substrate surface due to the light emitted from the light-emitting substance.

[0064] The functional article contains a luminescent substance in which the degree of decrease is similar to the degree of decrease of the active ingredient contained in the deposit of the functional composition formed on the substrate surface of the functional article.

[0065] The degree of decrease in the active ingredient and the degree of decrease in the luminescent substance are determined to be approximately the same according to the following procedure: The dry friction test and the wet friction test described below are each performed five times separately. In both the dry friction test and the wet friction test, the content of the active ingredient and the luminescent substance are measured before and after the test. For each of the dry friction test and the wet friction test, the degree of decrease in the active ingredient and the degree of decrease in the luminescent substance are calculated based on the decrease formula below. In both the dry friction test and the wet friction test, if the degree of decrease in the luminescent substance is greater than the degree of decrease in the active ingredient, and the absolute value of the difference between the degree of decrease in the luminescent substance and the degree of decrease in the active ingredient is 30% or less, then it is considered that "the degree of decrease in the active ingredient and the degree of decrease in the luminescent substance are approximately the same." The target compound refers to the active ingredient or the luminescent substance. Degree of reduction (%) = 100 × (Amount of target compound before the test - Amount of target compound after the test) / Amount of target compound before testing

[0066] The absolute difference between the degree of decrease in the active ingredient and the degree of decrease in the luminescent substance is preferably 30% or less, more preferably 20% or less, more preferably 15% or less, and more preferably 10% or less.

[0067] The above dry friction test refers to a dry test conducted in accordance with JIS L0849:2013 using a Type I friction tester (clock meter), in which the active composition is rubbed back and forth 20 times against the substrate. When performing the dry friction test multiple times, a new white cotton cloth for friction shall be used for each dry friction test.

[0068] The above wet friction test refers to a wet test conducted in accordance with JIS L0849:2013 using a Type I friction tester (clock meter), in which the active composition is rubbed back and forth 20 times against the substrate. When performing the wet friction test multiple times, a new white cotton cloth for friction shall be used for each wet friction test.

[0069] The active ingredient and luminescent substance can be easily selected by combining compounds that can produce an aqueous solution of 0.5% by mass or more at 1 atmosphere (1013.25 hPa) and 25°C, thereby ensuring that the degree of reduction of the active ingredient and luminescent substance is similar. Even if the active ingredient and luminescent substance cannot be dissolved in water at a concentration of 0.5% by mass or more on their own, they may still be able to produce an aqueous solution of 0.5% by mass or more by using dissolving aids such as surfactants, solubilizers, solvents, solubilizers, stabilizers, and pH adjusters. In such cases, the active ingredient or luminescent substance may be used together with the dissolving aid. Examples of surfactants include anionic surfactants, cationic surfactants, nonionic surfactants, and silicone surfactants. Examples of solubilizers include acetone, isopropanol, soybean oil, hydrogenated castor oil, isostearic acid, and medium-chain triglyceride. Examples of solvents include squalane, squalene, stearyl alcohol, isostearyl alcohol, oleyl oleate, rapeseed oil, potassium bromide, and petroleum benzine. Examples of solubilizers include meglumine, glycerin, adipic acid, ether, olive oil, isopropyl myristate, sodium benzoate, diisopropanolamine, monoethanolamine, ethylenediamine, oleyl alcohol, pric acid, diisopropyl sebacate, triacetin, methanol, and propionic acid. Examples of pH adjusters include acetic acid, potassium acetate, sodium acetate, ammonium carbonate, citric acid, sodium citrate, lactic acid, phosphoric acid, hydrochloric acid, tartaric acid, boric acid, and gluconic acid.

[0070] The amount of active ingredient or luminescent substance dissolved in water can be measured, for example, according to the following procedure. Specifically, 0.5 g of the active ingredient or luminescent substance is added to 10 g of water, and the mixture is stirred with a stirrer for 1 hour at 25°C and 1 atm to prepare a mixture. 1 mL of the mixture is filtered through a polytetrafluoroethylene (PTFE) filter with a pore size of 0.2 μm to obtain a filtrate. After measuring the mass (g) of the filtrate, the amount of active ingredient or luminescent substance in the filtrate is quantified by high-performance liquid chromatography (HPLC), and the amount of active ingredient or luminescent substance dissolved in water (mass%) is calculated. For example, in the case of a fluorescent whitening agent, which is one of the luminescent substances, the HPLC conditions are as follows: A standard is prepared by dissolving the fluorescent whitening agent in acetonitrile to a concentration of 0.5 mass%. The substance concentration of the fluorescent whitening agent in the filtrate is calculated from a calibration curve prepared using the standard. Column: Agilent Corporation, product name "InfinityLabPoroshell 120 Phenyl-Hexyl 4μm" Column size: 4.6 x 150 mm Mobile phase: A) 20 mM ammonium acetate aqueous solution, B) 80% by volume acetonitrile, 20% by volume methanol The flow rate is 1.0 mL / min. Column temperature: 25℃ Detection wavelength: 430nm

[0071] The active ingredients and luminescent substances in the active composition attached to the substrate of the functional article decrease at a similar rate with use. When the amount of active ingredients attached to the substrate surface of the functional article falls below the minimum amount necessary for the active ingredients to exert a predetermined effect (effective usage amount), the amount of luminescent substances is adjusted so that there is no change in the brightness of the substrate surface due to the synchrotron radiation emitted from the luminescent substances by irradiation with ultraviolet light in the UVA range.

[0072] On the other hand, if the amount of active ingredient attached to the substrate surface of a functional article is equal to or exceeds the effective usage amount, the amount of luminescent material is adjusted so that the amount of luminescent light emitted from the luminescent material by irradiation with ultraviolet light in the UVA range causes a change in the brightness of the substrate surface.

[0073] When the amount of active ingredient is greater than or equal to the effective usage amount, the amount of luminescent material may be adjusted so that the amount of luminescent light emitted from the luminescent material causes a change in the brightness of the substrate surface. On the other hand, when the amount of active ingredient is less than the effective usage amount, the amount of luminescent material may be adjusted so that the amount of luminescent light emitted from the luminescent material causes no change in the brightness of the substrate surface (the brightness change is lost). In this case, when it is confirmed that the brightness change of the substrate surface has been lost, it means that the amount of active ingredient is less than the effective usage amount.

[0074] Therefore, when the amount of active ingredient is several times the effective usage amount (preferably 1.2 times or more the effective usage amount, more preferably 1.25 times or more the effective usage amount, and more preferably 1.3 times or more the effective usage amount), it is preferable to adjust the amount of luminescent material so that the amount of luminescent light emitted from the luminescent material causes a change in the brightness of the substrate surface. On the other hand, when the amount of active ingredient is less than several times the effective usage amount (preferably less than 1.2 times the effective usage amount, more preferably less than 1.25 times the effective usage amount, and more preferably less than 1.3 times the effective usage amount), it is preferable to adjust the amount of luminescent material so that the amount of luminescent light emitted from the luminescent material causes no change in the brightness of the substrate surface (the brightness change is lost). This allows for sufficient time to check the amount of active ingredient and take appropriate action before the amount of active ingredient falls below the effective usage amount. In this invention, "several times the effective usage amount" means n times the effective usage amount (n is a number of 1 or more). n is preferably 1 to 5, and more preferably 1.5 to 3.

[0075] The amounts of active ingredients and luminescent substances in the active composition can be adjusted, for example, in the following manner. For example, the effective amount of active ingredient to be attached to the substrate surface is measured in advance. This effective amount is the minimum amount necessary for the active ingredient to exert the desired effect (hereinafter sometimes referred to as "effective effect") on the substrate to which the active ingredient is attached. The amount of active ingredient to be attached to the substrate before use of the functional article (initial amount of active ingredient) is determined, and the number of times the initial amount of active ingredient is compared to the effective amount is calculated, and this value (initial amount of active ingredient / effective amount used) is defined as the "content index".

[0076] On the other hand, in the case of the luminescent material, the minimum amount of luminescent material that causes a change in the brightness of the substrate surface due to the synchrotron radiation emitted from the luminescent material by irradiation with ultraviolet light in the UVA range and that adheres to the substrate surface is measured in advance as the "standard content," and the amount obtained by multiplying this standard content of luminescent material by the content index of the above-mentioned active ingredient is set as the initial amount of luminescent material.

[0077] After determining the initial amounts of the active ingredient and the luminescent substance according to the procedure described above, the active ingredient is further added to the initial amount of the active ingredient. According to this procedure, when the amount of the active ingredient is several times the effective usage amount, the amount of the luminescent substance can be adjusted so that the amount of luminescent light emitted from the luminescent substance causes a change in the brightness of the substrate surface. On the other hand, when the amount of the active ingredient is less than several times the effective usage amount, the amount of the luminescent substance can be adjusted so that the amount of luminescent light emitted from the luminescent substance does not cause a change in the brightness of the substrate surface (the brightness change is lost).

[0078] In this invention, the units for the effective amount used, initial amount, and adjusted content of the active ingredient are appropriately selected depending on the type of active ingredient. The units for the standard content, initial amount, and adjusted content of the luminescent substance are appropriately selected depending on the type of luminescent substance. Examples of units for the effective amount used, initial amount, and adjusted content of the active ingredient include mass per unit area. Examples of units for the standard content, initial amount, and adjusted content of the luminescent substance include mass per unit area.

[0079] The minimum amount of the active ingredient required to exert the desired effect (effective action) can be determined according to the criteria corresponding to the effect of the active ingredient.

[0080] For example, if the active ingredient is an antiviral agent, the minimum required amount of the active ingredient (effective usage amount) is defined as the amount of antiviral agent that achieves 99% antiviral efficacy as measured in accordance with ISO 18184.

[0081] If the active ingredient is an antibacterial agent, the minimum required amount of the active ingredient (effective usage amount) shall be the amount of antibacterial agent that yields 99% antibacterial activity as measured in accordance with ISO 20743.

[0082] If the active ingredient is an anti-allergen, the minimum necessary amount (effective dose) of the anti-allergen should be determined according to the following procedure.

[0083] For example, an allergen solution with a protein content of 10 μg / ml is prepared by dissolving the cold-dried powder of the allergen in phosphate buffer (pH 7.6). As the allergen, for example, a commercially available product from Cosmo Bio under the trade name "Mite Extract-Df" can be used.

[0084] Dilute the anti-allergen agent with deionized water to prepare a 1% by mass solution of the anti-allergen agent.

[0085] Next, prepare a test tube containing 1 milliliter of the above allergen solution, add 100 microliters of the above anti-allergen agent dilution to the test tube, and shake at 37°C for 16 hours.

[0086] Next, the amount of Der f1 present in the liquid in the test tube, W1 (ng / milliliter), is measured using a measuring device. The measuring device used can be the one commercially available from Nichinichi under the product name "ELISA kit".

[0087] Next, an allergen solution is supplied to another test tube, and the amount W0 (ng / milliliter) of Der f1 present in the liquid in the test tube is measured in the same manner as described above, except that a phosphate buffer (pH 7.6) is supplied to this test tube.

[0088] Then, the allergen inhibition rate (%) is calculated based on the following formula, and the amount of the anti-allergen agent at which the allergen inhibition rate reaches 60% is defined as the minimum required amount (effective usage amount) of the active ingredient. Allergen inhibition rate (%) = 100 - (W1 / W0) × 100

[0089] Since it is easy to adjust the amount of the active ingredient to be not less than the effective usage amount, the mass per unit area of the active ingredient adhering to the substrate surface is preferably 0.001 mg / cm 2 or more, more preferably 0.002 mg / cm 2 or more, still more preferably 0.01 mg / cm 2 or more, and even more preferably 0.05 mg / cm 2 or more. The mass per unit area of the active ingredient adhering to the substrate surface is preferably 10 mg / cm 2 or less.

[0090] When the active ingredient is an antiviral agent, since it is easy to adjust the amount to be not less than the effective usage amount, the mass per unit area of the antiviral agent adhering to the substrate surface is preferably 0.001 mg / cm 2 or more, more preferably 0.002 mg / cm 2 or more, still more preferably 0.01 mg / cm 2 or more, and even more preferably 0.05 mg / cm 2 or more. The mass per unit area of the antiviral agent adhering to the substrate surface is preferably 10 mg / cm 2 or less.

[0091] When the active ingredient is an anti-allergen agent, since it is easy to adjust the amount to be not less than the effective usage amount, the mass per unit area of the anti-allergen agent adhering to the substrate surface is preferably 0.002 mg / cm 2 or more, and 0.004 mg / cm2 The above is more preferable, 0.01 mg / cm³ 2 The above is more preferable, 0.05 mg / cm³ 2 The above is more preferable. The mass per unit area of ​​the anti-allergen agent adhering to the substrate surface is 10 mg / cm². 2 The following are preferable.

[0092] When the active ingredient is an antibacterial agent, it is easy to adjust the amount to exceed the effective usage amount, so the mass of the antibacterial agent per unit area attached to the substrate surface is 0.001 mg / cm². 2 The above is preferable, and 0.002 mg / cm³ 2 The above is more preferable, 0.01 mg / cm³ 2 The above is more preferable, 0.05 mg / cm³ 2 The above is more preferable. The mass of the antibacterial agent per unit area attached to the substrate surface is 10 mg / cm². 2 The following are preferable.

[0093] Since it is easy to adjust the content of the luminescent substance to be above the standard content, the mass of the luminescent substance per unit area attached to the substrate surface is 0.0001 mg / cm². 2 The above is preferable, and 0.0002 mg / cm³ 2 The above is more preferable, 0.005 mg / cm³ 2 The above is more preferable. The mass per unit area of ​​the luminescent material attached to the substrate surface is 1 mg / cm². 2 The following are preferable.

[0094] To more accurately confirm the presence or absence of an effective effect due to the active ingredient, the ratio of the mass per unit area of ​​the active ingredient attached to the substrate surface to the mass per unit area of ​​the luminescent substance attached to the substrate surface (mass per unit area of ​​the active ingredient attached to the substrate surface / mass per unit area of ​​the luminescent substance attached to the substrate surface) is preferably 100 or less, more preferably 50 or less, and more preferably 25 or less. The ratio of the mass per unit area of ​​the active ingredient attached to the substrate surface to the mass per unit area of ​​the luminescent substance attached to the substrate surface (mass per unit area of ​​the active ingredient attached to the substrate surface / mass per unit area of ​​the luminescent substance attached to the substrate surface) is preferably 1 or more, more preferably 5 or more, and more preferably 8 or more.

[0095] Furthermore, in functional articles, the active composition is removed and reduced with use, but it is preferable that, after performing a dry friction test of 20 back-and-forth cycles (considered as one cycle) on the adhering body of the active composition on the substrate using a Type I friction tester (clock meter) in accordance with JIS L0849:2013, five times, the brightness of the surface of the functional article changes due to the synchrotron radiation emitted from the luminescent material when the adhering body of the active composition is irradiated with ultraviolet light in the UVA range. It is preferable that the functional article is configured such that the brightness of the surface of the functional article changes due to the synchrotron radiation emitted from the luminescent material after the above friction test, as this allows the effect of the active ingredient to be sustained over a long period of time.

[0096] Next, we will explain the method for creating functional articles and the method for confirming the active ingredients using these functional articles.

[0097] A coating solution is prepared for adhering a working composition to a substrate constituting a functional article. The coating solution is prepared by dissolving or dispersing the working composition in a solvent. The solvent is not particularly limited and includes, for example, aqueous media, toluene, methyl ethyl ketone, ethyl acetate, and alcohol. Examples of aqueous media include water or a mixture of water and an organic solvent (e.g., a lower alcohol).

[0098] The amounts of active ingredients and luminescent substances in the coating solution can be adjusted, for example, in the following manner. First, measure the effective amount of active ingredients and the standard amount of luminescent substances. Determine the amount of active ingredients to be greater than or equal to the effective amount (hereinafter sometimes referred to as the "adjusted amount"). Based on the rate of decrease of the active ingredients, simulate the amount of friction until the amount of active ingredients reaches the effective amount or several times the effective amount (for example, 1.2 times, 1.25 times, 1.3 times, etc.). Next, based on the rate of decrease of the luminescent substances, determine the amount of luminescent substances (hereinafter sometimes referred to as the "adjusted amount") so that the amount of luminescent substances becomes the standard amount when the friction amount assumed above is reached. Then, prepare the coating solution by dissolving or dispersing the active ingredients and luminescent substances in a solvent in a general manner so that the ratio of the amount of active ingredients to the amount of luminescent substances (amount of active ingredients / amount of luminescent substances) is the same as the ratio of the adjusted amount of active ingredients to the adjusted amount of luminescent substances (adjusted amount of active ingredients / adjusted amount of luminescent substances).

[0099] The method for attaching the active composition to the substrate of a functional article is not particularly limited. For example, a coating solution can be prepared by uniformly dissolving or dispersing (suspending or emulsifying, etc.) both the active ingredient and the luminescent substance in a solvent, spraying this coating solution onto the substrate or applying it using a coating tool (e.g., brush, cloth, etc.), and then drying and removing the solvent to form an adherent body of the active composition on the surface of the substrate.

[0100] Furthermore, the initial amounts of the active ingredient and luminescent substance contained in the adsorbent of the active composition formed on the surface of the substrate must exceed the effective usage amount of the active ingredient and the standard content of the luminescent substance, respectively.

[0101] Furthermore, any residue of the active composition formed on the substrate of a functional article is removed and reduced over time by contact with human hands, clothing, and other items during use. Since the active ingredients and luminescent substances in the active composition are combined in such a way that their rates of decrease are roughly the same, the rate of decrease of the active ingredients and luminescent substances on the substrate over time is generally similar. For example, when the amount of the active ingredient becomes half of the initial amount, the amount of the luminescent substance becomes half of the initial amount or less than half of the initial amount.

[0102] Furthermore, while the rate of decrease of the active ingredient and the luminescent substance in the active composition on the substrate is roughly the same, the rate of decrease (degree of decrease) of the luminescent substance is set to be slightly faster than the rate of decrease (degree of decrease) of the active ingredient. Therefore, when the remaining amount of the luminescent substance reaches the standard content, the remaining amount of the active ingredient is close to the effective usage amount, and is greater than the effective usage amount, so it can be expected that the remaining amount of the active ingredient will soon fall below the effective usage amount.

[0103] The threshold for the amount of luminescent material present in a functional article is the reference content, which determines whether or not the brightness of the substrate surface changes due to the synchrotron radiation emitted from the luminescent material. By checking whether or not a change in brightness occurs on the substrate surface due to the synchrotron radiation emitted from the luminescent material, if no change occurs in brightness on the substrate surface, the remaining amount of the active ingredient on the substrate surface is close to the effective usage amount, and is greater than the effective usage amount. This indicates that the remaining amount of the active ingredient will soon fall below the effective usage amount, or that the remaining amount of the active ingredient has already fallen below the effective usage amount.

[0104] Specifically, ultraviolet light in the UVA range is irradiated onto the area where the active composition is attached to the substrate of the functional article (ultraviolet irradiation step). Synchrotron radiation is emitted from the light-emitting material by this ultraviolet irradiation, and it is checked whether the brightness of the substrate surface of the functional article changes due to this synchrotron radiation. If there is no change in the brightness of the substrate surface, that is, if the change in brightness of the substrate surface is lost, it can be confirmed that the amount of active ingredient is close to the effective usage amount, but greater than the effective usage amount, and that the remaining amount of active ingredient will soon fall below the effective usage amount, or that the remaining amount of active ingredient has already fallen below the effective usage amount.

[0105] On the other hand, when ultraviolet light in the UVA range is irradiated onto the area where the active composition is attached to the substrate of the functional article, and synchrotron radiation is emitted from the light-emitting material as a result of this ultraviolet irradiation, and the brightness of the surface of the substrate of the functional article changes as a result of this synchrotron radiation, it can be confirmed that the remaining amount of the active ingredient is greater than or equal to the effective amount used, and that the active ingredient of the functional article is exerting its effective effect (confirmation step).

[0106] The presence or absence of a change in the brightness of the substrate surface is determined according to the following procedure. First, a substrate (hereinafter referred to as the "reference substrate") is prepared before any deposits of the active composition are formed on its surface. On the surface of this reference substrate, a mercury lamp light source is used to expose it to ultraviolet light in the UVA region with a wavelength of 330-385 nm at an irradiance of 70 mW / cm². 2 The substrate is irradiated with ultraviolet light, and while under this ultraviolet irradiation state, the brightness of the surface of the reference substrate is measured as the "reference brightness" using visible light with wavelengths of 420 to 800 nm emitted from the light-emitting material.

[0107] Next, a mercury lamp light source was used to illuminate the surface of the substrate (hereinafter referred to as the "measurement substrate") on which the active composition had been deposited, with ultraviolet light in the UVA region with a wavelength of 330-385 nm at an irradiance of 70 mW / cm². 2 The substrate is irradiated with ultraviolet light, and while under this ultraviolet irradiation state, the brightness of the surface of the substrate is measured as "measured brightness" using visible light with wavelengths of 420 to 800 nm emitted from the light-emitting material.

[0108] The above reference brightness and measured brightness can be measured using, for example, the following equipment: A mercury lamp sold by Olympus under the product name "U-RFL-T" can be used. A mirror unit sold by Olympus under the product name "U-MWU2" can be used. A polarizing microscope sold by Olympus under the product name "BX-51" (5x objective) can be used. Image analysis software sold by Olympus under the product name "Stream" can be used, and the brightness of the quantified image obtained by adjusting the exposure to the maximum level at which the peaks of each wavelength of RGB do not saturate can be used as the brightness of the substrate surface.

[0109] Then, the amount of change in brightness is calculated based on the following formula. If the amount of change in brightness is 15 or more, it is considered that a change in brightness has occurred on the substrate surface. Conversely, if the amount of change in brightness is less than 15, it is considered that the change in brightness on the substrate surface has been lost. Change in luminance = Measured luminance - Reference luminance

[0110] Thus, with the above-described functional article, it is possible to confirm whether a sufficient amount of the active ingredient remains on the substrate to exert its effect by simply irradiating the substrate with UVA ultraviolet light.

[0111] If it is confirmed that sufficient amounts of the active ingredient remain on the substrate to exert its effect, the functional article can be used continuously. However, if sufficient amounts of the active ingredient do not remain on the substrate to exert its effect, a new deposit of the active composition should be formed on the substrate in the same manner as described above, and then the use of the functional article should be continued.

[0112] Furthermore, when forming a new adhesion of the active composition on a substrate, it is preferable to remove any remaining adhesion of the active composition on the substrate before forming the new adhesion of the active composition on the substrate, in order to eliminate the influence of any old active composition remaining on the substrate and to accurately confirm the amount of active ingredient remaining. [Examples]

[0113] The present invention will be described more specifically below with reference to examples, but the present invention is not limited thereto.

[0114] The following active ingredients and fluorescent substances were used in the examples and comparative examples. [Active ingredients] • Antiviral agent (sodium dodecylbenzenesulfonate, water-soluble) • Antiallergen agent (polyvinylphenol, water-soluble) • Antibacterial agent (fumaric acid, water-soluble)

[0115] [Luminescent material] • Fluorescent substance 1 (manufactured by Nippon Fluorescent Chemicals Co., Ltd., product name "Special Phosphor No. 490-E") • Fluorescent substance 2 (manufactured by Shinloihi Co., Ltd., product name "LeuchiMarker R70") • Fluorescent substance 3 (manufactured by Shinloihi Co., Ltd., product name "MLCB-12 GREEN")

[0116] Table 1 shows the effective usage amount of the active ingredient. Table 2 shows the standard content of fluorescent substances in a flat, square test specimen [black polyvinyl chloride sheet (black PVC sheet), transparent polyethylene sheet (transparent PE sheet)] with sides of 10 cm.

[0117] The above-mentioned antiviral agent, anti-allergen agent, and antibacterial agent were all compounds that could be dissolved alone in water at 1 atmosphere (1013.25 hPa) and 25°C to produce an aqueous solution of 0.5% by mass or more. The above-mentioned fluorescent substances 1 to 3 were all compounds that could be dissolved alone in water at 1 atmosphere (1013.25 hPa) and 25°C to produce an aqueous solution of 0.5% by mass or more.

[0118] (Examples 1-3, Comparative Examples 1 and 2) A coating solution was prepared by mixing the specified amounts of the active ingredient, fluorescent substance, water, and ethanol shown in Table 3, and dissolving the active composition containing the active ingredient and fluorescent substance in an aqueous medium containing water and ethanol.

[0119] The obtained coating solution was sprayed onto a flat, square test piece [black polyvinyl chloride sheet (black PVC sheet)] with sides of 10 cm, and the coating solution was uniformly applied to the entire surface of one side of the test piece to adhere the active composition and produce a functional article.

[0120] The ratio of the mass per unit area of ​​the active ingredient attached to the surface of the test specimen (substrate) to the mass per unit area of ​​the luminescent substance attached to the surface of the test specimen (substrate) (mass per unit area of ​​the active ingredient attached to the surface of the test specimen / mass per unit area of ​​the luminescent substance attached to the surface of the test specimen) is recorded in the "Mass Ratio" column.

[0121] (Examples 4-6, Comparative Examples 3 and 4) A coating solution was prepared by mixing the specified amounts of the active ingredient, fluorescent substance, water, and ethanol shown in Table 4, and dissolving the active composition containing the active ingredient and fluorescent substance in an aqueous medium containing water and ethanol.

[0122] The obtained coating solution was sprayed onto a flat, square test piece [transparent polyethylene sheet (transparent PE sheet)] with sides of 10 cm, and the coating solution was uniformly applied to the entire surface of one side of the test piece to adhere the active composition and produce a functional article.

[0123] The ratio of the mass per unit area of ​​the active ingredient attached to the surface of the test specimen (substrate) to the mass per unit area of ​​the luminescent substance attached to the surface of the test specimen (substrate) (mass per unit area of ​​the active ingredient attached to the surface of the test specimen / mass per unit area of ​​the luminescent substance attached to the surface of the test specimen) is recorded in the "Mass Ratio" column.

[0124] (Difference in the degree of decrease of active ingredients and fluorescent substances) In the functional articles obtained in the examples and comparative examples, dry friction tests and wet friction tests were performed in accordance with the above procedure, and the degree of reduction of the active ingredient and the degree of reduction of the fluorescent substance were measured.

[0125] Dry friction tests revealed that in both the examples and comparative examples, the difference between the rate of decrease of the active ingredient and the rate of decrease of the fluorescent substance was 30% or less, and the rate of decrease of the fluorescent substance was greater than the rate of decrease of the active ingredient.

[0126] The results of the wet friction test showed that in both the examples and comparative examples, the difference between the rate of decrease of the active ingredient and the rate of decrease of the fluorescent substance was 10% or less, and the rate of decrease of the fluorescent substance was greater than the rate of decrease of the active ingredient.

[0127] (Initial amounts of active ingredients and fluorescent substances) The content of active ingredients and fluorescent substances in the adhesion of the active composition formed on the substrate surface of the functional article immediately after its manufacture was measured, and the results are shown in the "Initial amount of active ingredients" and "Initial amount of fluorescent substances" columns of "Before testing" in Tables 3 and 4.

[0128] (Change in brightness before the test) The change in brightness of the substrate surface of the functional article immediately after fabrication was measured using the procedure described above, and the results are shown in the "Change in Brightness" column under "Before Test" in Tables 3 and 4.

[0129] (Efficacy test of active ingredients after dry friction test) The above dry friction test was performed 5 or 10 times in the manner described above. Next, the presence or absence of the effective action of the active ingredients in the adhering substances of the functional composition present on the substrate surface of the functional article was measured.

[0130] For antiviral agents, antiviral activity was measured in accordance with ISO 18184. Agents with an antiviral activity of 99% or higher were classified as "effective," while those with an antiviral activity of less than 99% were classified as "ineffective."

[0131] For anti-allergen agents, the allergen suppression rate was measured according to the procedure described above. If the allergen suppression rate was 90% or higher, it was considered "effective," and if the allergen suppression rate was less than 90%, it was considered "ineffective."

[0132] For antibacterial agents, antibacterial activity was measured in accordance with ISO 20743. Agents with an antibacterial activity of 99% or higher were classified as having "effective activity," while those with an antibacterial activity of less than 99% were classified as having "no effective activity."

[0133] If the active ingredient does not have an effective effect, it can be determined that the amount of the active ingredient is less than the effective dose.

[0134] (Effective action test of active ingredients after wet friction test) The wet friction test described above was performed five times in the manner described above. Next, the presence or absence of the active ingredient's effective action in the adhering substance of the active composition present on the substrate surface of the functional article was measured. The determination of the presence or absence of the effective action was made in the same manner as in the effective action test of the active ingredient after the drying test.

[0135] (Change in brightness after the test) For each of the above-mentioned dry friction tests and wet friction tests, the change in brightness of the substrate surface of the functional article was measured in the manner described above, and the results are shown in the "Change in Brightness" column of Tables 3 and 4.

[0136] [Table 1]

[0137] [Table 2]

[0138] [Table 3]

[0139] [Table 4] [Industrial applicability]

[0140] In the functional article of the present invention, when ultraviolet light in the UVA range is irradiated onto the surface of the substrate containing the active composition, and the change in brightness of the surface of the functional article is lost (no change in brightness), it can be easily confirmed that the amount of active ingredient is less than the effective amount used, and that the active ingredient is not exerting its effective effect.

[0141] The coating liquid of the present invention can be applied to a substrate to form an adherent body of the active composition on the substrate, thereby manufacturing the functional article described above.

[0142] (Cross-reference of related applications) This application claims priority under Japanese Patent Application No. 2021-84226, filed on 18 May 2021, and Japanese Patent Application No. 2022-17316, filed on 7 February 2022, the disclosures of this application being incorporated herein by reference to those applications in their entirety.

Claims

1. Substrate and A functional article comprising an attachment of an active composition containing an active ingredient and a luminescent substance, which is attached to the above-mentioned substrate, If the amount of active ingredient adhering to the above substrate is less than the effective usage amount, the change in brightness of the surface of the functional article caused by synchrotron radiation emitted from the light-emitting substance due to irradiation of the adherent body of the active composition with ultraviolet light in the UVA range will be lost. A functional article characterized in that, in dry friction tests and wet friction tests, the degree of decrease of the luminescent substance is greater than the degree of decrease of the active ingredient, and the absolute value of the difference between the degree of decrease of the luminescent substance and the degree of decrease of the active ingredient is 30% or less.

2. The functional article according to claim 1, characterized in that, after performing a friction test of 20 back-and-forth movements on the adherent surface of the functional composition on the substrate by a dry test using a Type I friction tester (clock meter) in accordance with JIS L0849:2013, the brightness of the surface of the functional article changes due to synchrotron radiation emitted from the luminescent substance when the adherent surface of the functional composition is irradiated with ultraviolet light in the UVA range.

3. The mass of the active ingredient per unit area attached to the substrate surface is 0.001 mg / cm². 2 The functional article according to claim 1 or 2, characterized in that it is as described above.

4. The mass per unit area of ​​the luminescent material attached to the substrate surface is 0.0001 mg / cm². 2 The functional article according to claim 1 or 2, characterized in that it is as described above.

5. A functional article according to claim 1 or 2, characterized in that the ratio of the mass per unit area of ​​the active ingredient attached to the substrate surface to the mass per unit area of ​​the luminescent substance attached to the substrate surface (mass per unit area of ​​the active ingredient attached to the substrate surface / mass per unit area of ​​the luminescent substance attached to the substrate surface) is 1 to 100.

6. The functional article according to claim 1 or 2, characterized in that the active ingredient is an antiviral agent, an antibacterial agent, an anti-allergen agent, or a deodorant.

7. The functional article according to claim 6, characterized in that the active ingredient is an antiviral agent, and the antiviral agent is a sulfonic acid compound.

8. The functional article according to claim 6, characterized in that the active ingredient is an anti-allergen agent, and the anti-allergen agent is an aromatic hydroxy compound.

9. The functional article according to claim 1 or 2, characterized in that the luminescent material contains a fluorescent material.

10. The functional article according to claim 9, characterized in that the luminescent substance is a fluorescent whitening agent.

11. A functional article characterized in that the fluorescent substance is one or more fluorescent substances selected from the group consisting of fluorescein 134, fluorescein 90, and fluorescein 213.

12. The functional article according to claim 1 or 2, characterized in that the active ingredient and the luminescent substance are compounds capable of producing an aqueous solution of 0.5% by mass or more at 1 atmosphere (1013.25 hPa) and 25°C.

13. A functional article comprising a substrate and an attachment of a functional composition containing an active ingredient and a luminescent substance, wherein if the amount of the active ingredient attached to the substrate is less than the effective usage amount, the attachment of the functional composition loses surface brightness due to synchrotron radiation emitted from the luminescent substance when the attachment of the functional composition is irradiated with ultraviolet light in the UVA range, and The process includes a confirmation step of checking the change in brightness of the surface of the functional article after it has been irradiated with ultraviolet light in the UVA range, and confirming that the amount of the active ingredient present is equal to or greater than the effective usage amount if the brightness of the surface of the functional article has changed. A method for confirming the active ingredient in the above-mentioned functional article, characterized in that, in a dry friction test and a wet friction test, the degree of decrease of the luminescent substance is greater than the degree of decrease of the active ingredient, and the absolute value of the difference between the degree of decrease of the luminescent substance and the degree of decrease of the active ingredient is 30% or less.

14. The method for confirming the active ingredient according to claim 13, characterized in that the luminescent substance contains a fluorescent substance.

15. It contains an active composition comprising an active ingredient and a luminescent substance, The above-mentioned active composition can be attached to a substrate. When the amount of the active ingredient in the adherent body of the above-mentioned active composition is less than the effective usage amount, irradiation of the adherent body of the above-mentioned active composition with ultraviolet light in the UVA range causes the change in brightness of the substrate surface on which the adherent body is formed, which was caused by synchrotron radiation emitted from the light-emitting substance, to be lost. A coating liquid characterized in that, in dry friction tests and wet friction tests, the degree of decrease of the luminescent substance is greater than the degree of decrease of the active ingredient, and the absolute value of the difference between the degree of decrease of the luminescent substance and the degree of decrease of the active ingredient is 30% or less.

Images