Chemical sensor, reagent, and method for detecting methyl benzoate

A chemical sensor with a tropane derivative auxiliary ligand enhances the detection sensitivity and selectivity for benzoic acid and its derivatives by using an aptamer on a sensor element, addressing the lack of effective detection methods.

JP7869164B2Active Publication Date: 2026-06-02KK TOSHIBA

Patent Information

Authority / Receiving Office
JP · JP
Patent Type
Patents
Current Assignee / Owner
KK TOSHIBA
Filing Date
2023-02-20
Publication Date
2026-06-02

AI Technical Summary

Technical Problem

Existing technologies lack a chemical sensor and reagent with high affinity for benzoic acid and effective methods for detecting benzoic acid and its derivatives.

Method used

A chemical sensor comprising a sensor element with a first and second electrode, an aptamer on its surface, and a tropane derivative in a solution, which enhances the affinity for benzoic acid derivatives by using a tropane derivative as an auxiliary ligand to increase detection sensitivity.

Benefits of technology

The sensor achieves high selectivity and sensitivity in detecting benzoic acid and its derivatives, including methyl benzoate, by leveraging the enhanced affinity provided by the tropane derivative.

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Abstract

To provide a chemical sensor, a reagent having high affinity for a benzoic acid and a benzoic acid derivative, and a method for detecting the benzoic acid and the benzoic acid derivative.SOLUTION: A chemical sensor includes a sensor element, a first electrode electrically connected with the sensor element, a second electrode electrically connected with the sensor element, an aptamer located on a surface of the sensor element, a solution covering the surface of the sensor element and the aptamer, and a tropane derivative contained in the solution and having a tropane skeleton.SELECTED DRAWING: Figure 1
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