Combined closure apparatus

Abstract

A combined closure apparatus (1), comprising connecting parts (20) and at least two closure modules (10). The at least two closure modules (10) are sequentially arranged at intervals. The connecting parts (20) are arranged between two adjacent closure modules. The connecting part (20) comprises at least two connecting members. The at least two connecting members comprise a first connecting member (101) and a second connecting member (201). The first connecting member (101) and the second connecting member (201) are connected to the adjacent closure modules (10), respectively. The closure apparatus enables a doctor to freely combine the closure modules (10) of different structures and sizes with the connecting parts (20) on the basis of the structure and size of a defect of an actual anatomical structure of a patient and to set the number of the closure modules (10), thereby improving the matching degree and the closure stability of the closure apparatus (1) and thus the closure effect.

Description

Combined sealing device

[0001] This application claims the benefit of Chinese patent application No. 2023114155952, filed on October 27, 2023. This application incorporates the entirety of the aforementioned Chinese patent application. Technical Field

[0002] The present invention relates to a combined blocking device, and in particular to a blocking device for blocking defects in anatomical structures. Background Art

[0003] In minimally invasive surgery for structural heart disease, selecting the appropriate sized occlusion device based on the morphology, location, size, and marginal tissue characteristics of the cardiac anatomical defect is crucial for surgical success. Preoperatively, transthoracic echocardiography (TTE) or X-ray imaging is used to comprehensively observe the morphology, location, size, margins, and relationship with surrounding tissue structures of the cardiac anatomical defect from multiple sections. Based on the ultrasound or X-ray findings, an appropriately sized occlusion device is selected for occlusion treatment. Currently, in clinical practice, occlusion devices are typically selected based on the maximum diameter of the cardiac anatomical defect as measured by TTE or X-ray imaging, with the size appropriately increased.

[0004] The anatomical defects of different patients may vary in structure and size. The structure and size of standardized occlusion devices cannot be suitable for the anatomical defects of all patients, but can only meet the anatomical defects of most patients, which will cause postoperative complications and risks. For example: in the occlusion treatment of atrial septal defect, an overly large occlusion device may result in incomplete endothelialization of the surface of the occlusion device or mitral regurgitation, or occlusion device abrasion may cause aorta-left atrium / right atrium fistula, mitral valve perforation / regurgitation and cardiac tamponade, etc., or a large atrial septal defect or a thin and short edge stump may cause the occlusion device to shift or fall off; in the occlusion treatment of patent ductus arteriosus, the occlusion device If the occluder protrudes too far into the pulmonary artery, it will cause stenosis of the left pulmonary artery. If the occluder protrudes too far into the descending aorta, it will cause stenosis of the descending aorta. In the closure treatment of patent foramen ovale, an oversized occluder can abrade the atrial or aortic wall, causing postoperative cardiac perforation or pericardial tamponade. Mechanical tension generated by mismatched occluder devices may cause atrial fibrillation. If the occluder device is not designed properly or the model is not matched, blood flow can easily pass through the gap between the tissue and the occluder device, resulting in residual shunt. In the closure treatment of ventricular septal defect, an oversized occluder can compress the tissue surrounding the membranous defect, causing edema and inflammation of the surrounding tissue, followed by fibrosis and atrioventricular block and left bundle branch block. All of the above shows that existing standardized occluders cannot fully meet the requirements of all patients with diverse anatomical defects, which may cause postoperative complications and risks.

[0005] Traditional occlusion devices feature a mesh-like structure with a disc and waist support. The disc and waist support are fixed in size and cannot be adjusted separately. The waist support is fixedly connected to both the left and right discs. This necessitates a wide variety of occlusion device sizes to meet the needs of diverse patients, requiring extensive training for doctors. During minimally invasive surgery, if the initially selected occlusion device is found to be inappropriately sized, a larger or smaller device must be replaced and re-implanted. This prolongs the procedure, wastes an entire occlusion device, and increases costs.

[0006] In clinical applications, due to the variability of cardiac anatomical defects among patients, doctors need to adjust the structure and size of the occlusion device's disc and waist during surgery. Currently, hospitals can only achieve this by stocking a large number of occlusion devices of varying specifications. These issues apply not only to the use of occlusion devices in structural heart disease but also to their application in the respiratory system, peripheral blood vessels, fistulas, or other bloodless cavities.

[0007] Currently, medical devices are manufactured on a large scale, in a regular, and batch basis, which ensures better quality control. However, customized products are not only costly but also difficult to control. This application aims to achieve industrialized production of customized products with high quality, enabling modular occlusion devices to better match individual anatomical defects.

[0008] Summary of the Invention

[0009] The technical problem to be solved by the present invention is to provide a combined blocking device in order to overcome the defect of poor adaptability of the blocking device in the prior art.

[0010] The present invention solves the above technical problems through the following technical solutions:

[0011] A combined sealing device, which is a multi-section combined structure, includes a connecting portion and at least two sealing modules; at least two of the sealing modules are arranged in sequence at intervals, and the connecting portion is provided between two adjacent sealing modules; the connecting portion includes at least two connecting members, the at least two connecting members include a first connecting member and a second connecting member, the first connecting member and the second connecting member are respectively connected to the adjacent sealing modules, and the first connecting member and the second connecting member are connected.

[0012] In the present solution, the blocking device is a multi-section combination structure, that is, the blocking modules are multiple relatively independent components, which have no influence on each other, that is, the change in shape of one blocking module will not cause the change in shape of the adjacent blocking modules, thus eliminating the problem of easy mutual influence between the blocking modules in the prior art, so that the distal blocking module is easily deformed into a gourd-shaped blocking module with an enlarged axial length, thus avoiding the damage caused to the implanted part of the human body by the gourd-shaped blocking module with an enlarged axial length, thereby increasing the safety and effectiveness of the blocking. At least two blocking modules are arranged in sequence at intervals, which can match the blocking of anatomical defects and improve the blocking effect. The blocking modules are connected by a first connecting member and a second connecting member. During the operation, blocking modules of appropriate structure and size are selected according to needs, and are connected into an integrated blocking device through the connecting part, and then the blocking device is implanted into the part that needs to be blocked during the operation, so that the blocking device can adapt to defects of different anatomical structures and make the blocking module more closely attached to the defects of the anatomical structure.

[0013] With the occlusion device of this solution, doctors can freely combine occlusion modules of different structures and sizes based on the structure and size of the anatomical defect, and set the number of occlusion modules, thereby increasing the compatibility and occlusion stability of the occlusion device and improving the occlusion effect. It can also reduce the chance of replacing the occlusion device during surgery, shorten the patient's bleeding time, and reduce the difficulty for doctors to select the occlusion device. The operation is simpler and more reliable, increasing the flexibility of the surgery and improving the success rate of the surgery. Furthermore, there is no need to prepare a large number of occlusion devices of different specifications. Instead, occlusion modules and connectors of different structures and sizes are independently manufactured first, and then, based on the structure and size of the patient's actual anatomical defect, more compatible occlusion modules and connectors are reassembled to form a modular occlusion device. In this way, a single device can treat a variety of anatomical defects, improving the compatibility of the occlusion device with the patient's anatomical defect, such as with cardiac anatomical defects, while increasing the flexibility of the surgery and improving the success rate of the surgery. The occlusion device of the present application can be used to treat defects in various anatomical structures of patients, and can be used not only for structural heart diseases, but also for the respiratory system, peripheral blood vessels, fistulas or cavities without blood passing through.

[0014] Preferably, the blocking module includes one of a disc-shaped structure, a cylindrical structure and a truncated cone-shaped structure.

[0015] In this approach, when the occlusion module is used to block anatomical defects, the disc-shaped occlusion module's end faces lie on the same plane, facilitating endothelial cell migration and accelerating endothelialization and postoperative recovery. Cylindrical or truncated cone-shaped occlusion modules can adapt to the structure of anatomical defects, improving occlusion effectiveness.

[0016] Preferably, the end surface of the blocking module is a plane or a curved surface, wherein the curved surface is a curved surface convex outward along the axial direction of the blocking module, or a curved surface concave inward along the axial direction of the blocking module.

[0017] In this solution, the end face of the occlusion module is flat, making it easy for endothelial cells to climb over it, accelerating endothelialization and postoperative recovery; the outward-convex curved surface can make the occluder have better shape recovery after being released from the delivery sheath; the inward-concave curved surface can make the occluder stably and firmly positioned and blocked during use, and not easy to shift, such as blocking the atrial septal defect in the heart.

[0018] Preferably, the blocking modules in the blocking device are all disc-shaped structures;

[0019] Alternatively, at least one of the blocking modules in the blocking device is a cylindrical structure, and the rest are disc-shaped structures;

[0020] Alternatively, at least one of the blocking modules in the blocking device is a truncated cone structure, and the rest are disc structures.

[0021] In this solution, different structural forms of the occlusion device are provided above, so as to be adaptable to diverse anatomical structures.

[0022] Preferably, the outer diameter of the connecting portion is smaller than the outer diameter of the blocking module.

[0023] In this solution, the above structural form can reduce the impact of deformation on the occlusion module's shape recovery, making it easier to return to its initial set shape after passing through a thinner delivery sheath. If the occlusion device enters a small anatomical defect, the occlusion module can adaptively reduce its radial diameter and extend its axial direction, thereby better accommodating longer anatomical defects and stably securing it within the implanted anatomical defect, ensuring effective occlusion and long-term implant safety.

[0024] Preferably, the diameters of the blocking modules of the blocking device are all different.

[0025] In this solution, the diameters of the occlusion modules are all different. When used in defects (cavities) of anatomical structures with varying inner diameters, such as the left atrial appendage, they can adapt to the inner diameters of various locations within the defects (cavities) of the anatomical structure, thereby improving the implantation and occlusion effects.

[0026] Preferably, the diameters of the blocking modules of the blocking device are all the same.

[0027] In this solution, the diameters of the occluding modules are all the same. When used in defects (cavities) of anatomical structures whose inner diameters do not change, such as when occluding a section of blood vessels with the same inner diameters, they can adapt to the inner diameters of various locations in the blood vessels, thereby improving the implantation and occluding effects.

[0028] Preferably, the diameters of the blocking modules of the blocking device are partially the same and others are different.

[0029] In this solution, the diameters of the occlusion module are partially the same and others are different. When used in defects (cavities) of anatomical structures with varying inner diameters and partially the same inner diameters, such as the left atrial appendage, it can adapt to the inner diameters of various parts of the defects (cavities) of the anatomical structure, thereby improving the implantation effect and the occlusion effect.

[0030] Preferably, the end surface where the blocking device is connected to the conveying device is a flat disk surface, or is provided with a connecting piece.

[0031] In this solution, the end surface where the occluding device connects to the delivery device is flat and smooth, allowing endothelial cells to easily crawl over it, accelerating endothelialization and postoperative recovery. Alternatively, a connector can be provided on the end surface where the occluding device connects to the delivery device, facilitating connection to an external delivery device.

[0032] Preferably, the axial length of the occlusion device is configured to adapt to the defect in the anatomical structure to be occluded.

[0033] In this solution, occluding modules and connecting parts of different axial lengths can be independently manufactured first, and then appropriate occluding modules and connecting parts can be selected and combined according to the structure and size of the anatomical defects actually measured in the patient, so that the occluding device can adapt to the patient's diverse anatomical structure.

[0034] Preferably, the connection portion is connected by means of chiseling, mortise and tenon or latch.

[0035] In this solution, the connection part can be connected in any of the above methods. During actual implementation, the corresponding connection method can be selected according to needs, thereby improving the convenience and flexibility of implementation.

[0036] Preferably, the occlusion device is used to treat defects in various anatomical structures of patients. Preferably, the occlusion device is used in structural heart disease, respiratory system, peripheral blood vessels, fistulas or cavities without blood passing through.

[0037] In this solution, the occluding device can be used to occlude defects in a variety of anatomical structures of patients. The occluding modules can be sequentially arranged in the defects of the anatomical structure, and the structure and size of the occluding modules can be selected according to the structure and size of the corresponding position in the defect of the anatomical structure, and the occluding modules can be combined together with the connecting part, so that the occluding modules can better fit the defects of the anatomical structure and improve the occluding effect of the defects of the anatomical structure. When applied to the left atrial appendage, the left atrial appendage can be regarded as a kind of anatomical defect, and a plurality of occluding modules can be abutted against the inner diameter of the left atrial appendage at various locations, thereby forming a stable connection with the left atrial appendage and improving the occluding effect. When applied to blood vessels, the occluding modules of corresponding sizes can be matched and formed into corresponding lengths according to the requirements of the occlusion, thereby improving the occluding effect.

[0038] Preferably, the first connecting member is provided with a telescopic portion, and the second connecting member has a first limiting portion; the second connecting member moves along the axial direction of the first connecting member and compresses the telescopic portion along the radial direction of the first connecting member; until the telescopic portion recovers and extends into the first limiting portion, so that the second connecting member is connected to the first connecting member.

[0039] In this solution, the second connector and the first connector can be connected to each other through relative movement along their axial directions. As the second connector and the first connector approach each other, the second connector can first compress the telescopic portion. When it moves to a position where the first limit portion and the telescopic portion are opposite, the telescopic portion can recover and extend into the first limit portion, thereby achieving the mutual connection and fixation of the first connector and the second connector. This type of connection is simple to operate, and when the first connector and the second connector are connected, a stable connection is formed, improving the reliability of the occlusion device after implantation in the patient's body.

[0040] Preferably, the second connecting member is sleeved on the outside of the first connecting member, and the first limiting portion is a first groove recessed from the inner wall of the second connecting member; a first accommodating cavity is provided in the first connecting member, and the telescopic portion is provided in the first accommodating cavity; the telescopic portion includes a protruding member passing through the side wall of the first accommodating cavity, the protruding member is telescopic along the radial direction of the first connecting member, and the protruding member is extended and connected to the first groove.

[0041] In this solution, the second connector is sleeved onto the outside of the first connector, enhancing the structural strength of the connection and making the axial dimensions of the connection more compact, shortening the distance between adjacent blocking modules and improving the blocking effect. The first accommodating cavity accommodates the telescopic portion, allowing the extension of the telescopic portion to extend or retract relative to the sidewall of the first accommodating cavity, thereby achieving axial connection between the second connector and the first connector.

[0042] Preferably, a second accommodating cavity is provided in the first connecting member, the second connecting member extends into the second accommodating cavity, and the first limiting portion is a second groove recessed from the outer wall of the second connecting member; the telescopic portion is located in the second accommodating cavity and connected to the inner wall of the second accommodating cavity, and the telescopic portion includes a protrusion protruding toward the interior of the second accommodating cavity, and the protrusion abuts against the second groove.

[0043] In this solution, the second connector extends into the second accommodating cavity of the first connector, enhancing the structural strength of the connection and making the axial dimensions of the connection more compact, shortening the distance between adjacent blocking modules and improving the blocking effect. The telescopic portion includes a protrusion that projects into the second accommodating cavity. This protrusion can be compressed and abutted against the second groove, resulting in a simple structure and a stable connection.

[0044] Preferably, the first connecting member is provided with a plug-in portion, the second connecting member has a fourth accommodating cavity, the first connecting member moves along the axial direction of the second connecting member, and the plug-in portion extends into the fourth accommodating cavity until the plug-in portion moves to a predetermined position and is restricted, so that the second connecting member is connected to the first connecting member.

[0045] In this embodiment, the second connector and the first connector are connected by relative movement along their axial direction. The plug portion extends into the fourth accommodating cavity until it moves to a predetermined position and is restrained, thereby securing the first and second connectors to each other. This connection is simple to operate, and once connected, the first and second connectors form a stable connection, improving the safety and reliability of the occlusion device after implantation in a patient.

[0046] Preferably, the first connecting member is provided with a first engaging portion, the second connecting member has a second engaging portion, and the first connecting member moves along the axial direction of the second connecting member until the first engaging portion and the second engaging portion are connected and restricted to each other, so that the second connecting member is connected to the first connecting member.

[0047] In this embodiment, the second connector and the first connector are connected by relative movement along their axial direction. The first and second engaging portions are connected and restrained, thereby securing the first and second connectors. This connection is simple to operate, and once connected, the first and second connectors form a stable connection, improving the safety and reliability of the occlusion device after implantation in a patient.

[0048] Preferably, the first connecting member has a locking portion and the second connecting member has a second limiting portion; the second connecting member rotates around the axis of the first connecting member, and the locking portion moves in the second limiting portion until it is locked in the second limiting portion, so that the second connecting member is connected to the first connecting member.

[0049] In this solution, the second connector rotates around the axis of the first connector, achieving a mutual rotational connection between the two. This connection method is simple and easy to operate. Moreover, when the first connector and the second connector are connected, they form a stable connection, improving the reliability of the occlusion device after implantation in the patient.

[0050] Preferably, the locking portion is a protrusion radially protruding from the first connecting member; the second limiting portion includes a guide section, a transition section and a limiting section connected in sequence, the guide section extends from the end of the second connecting member along the axial direction of the second connecting member, the transition section extends along the circumferential direction of the second connecting member, and the limiting section extends along the axial direction of the second connecting member and is opposite to the axial extension direction of the guide section.

[0051] In this solution, the protrusion can move axially along the second connector within the guide section, then move circumferentially along the second connector within the transition section, and then move axially along the second connector into the limiting section, thereby achieving connection between the first connector and the second connector and limiting the axial and radial positions of the first connector. This connection method is simple, and the protrusion and the second limiting portion are respectively provided on the first connector and the second connector, making the structure reliable and stable. In addition, the above structure is also easy to disassemble. When the structure or size of the blocking module needs to be adjusted, it can be easily disassembled and replaced with a suitable blocking module.

[0052] Preferably, the second limiting portion is a limiting hole, and the limiting hole passes through the side wall of the second connecting member.

[0053] In this solution, the positioning of the protrusion can be limited by the limiting hole, and when performing the connection operation, it is easy to observe the position of the protrusion in the limiting hole, thereby improving the convenience of operation.

[0054] Preferably, an abutment portion is further provided in the second connecting member, and the abutment portion is extended and retracted along the axial direction of the first connecting member and abuts against the end surface of the first connecting member facing the second connecting member.

[0055] In this solution, the abutting portion can provide a supporting force in the axial direction of the first connecting member, so that the protrusion can be abutted within the limiting section, thereby improving the reliability of the connection between the first connecting member and the second connecting member.

[0056] Preferably, the locking portion and the second limiting portion are an internal thread and an external thread respectively, one of the internal thread and the external thread is provided on the first connecting member, and the other is provided on the second connecting member.

[0057] In this solution, the connection between the first connecting member and the second connecting member is achieved by matching the internal and external threads. This connection structure is simple and the connection method is easy to operate.

[0058] Preferably, the connecting portion further includes a third connecting member, and the first connecting member and the second connecting member are connected via the third connecting member, or after the first connecting member and the second connecting member are connected, the third connecting member is sleeved on the outside of the first connecting member and / or the second connecting member.

[0059] In this solution, the first connecting member can be connected to the second connecting member through a third connecting member, or after the first connecting member and the second connecting member are connected, the third connecting member is sleeved on the outside of the first connecting member and / or the second connecting member, thereby realizing the connection between the two blocking modules.

[0060] Preferably, the third connecting member is a sleeve.

[0061] In this solution, the above structural form facilitates operation and improves ease of use. The ends of the sleeve are connected to the first and second connectors, respectively. This connection method can increase the axial length of the connection to accommodate longer anatomical defects. Alternatively, the first and second connectors can be connected together first, and the sleeve can be placed outside the first and / or second connectors. This can further stabilize the connection and increase the outer diameter and surface smoothness of the connection.

[0062] The positive progress effect of the present invention is:

[0063] Through the occlusion device in this solution, doctors can freely combine occlusion modules of different structures and sizes according to the structure and size of the patient's diverse anatomical defects, and set the number of occlusion modules, thereby increasing the matching degree and occlusion stability of the occlusion device and improving the occlusion effect. At the same time, it can also reduce the probability of replacing the occlusion device during surgery, reduce the patient's bleeding time, and reduce the difficulty of the doctor in selecting the occlusion device. The operation is simpler and more reliable, increasing the flexibility of the operation and improving the success rate of the operation. In addition, there is no need to prepare a large number of occlusion devices of different specifications. Instead, occlusion modules and connectors of different structures and sizes are independently manufactured first, and then, according to the structure and size of the patient's actual anatomical defects, more matching occlusion modules and connectors are reassembled to form a combined occlusion device. In this way, one device can cover the treatment of a variety of anatomical defects, which can not only improve the matching degree between the occlusion device and the patient's anatomical defects, but also increase the flexibility of the operation and improve the success rate of the operation. The occlusion device of the present application can be used to treat defects in various anatomical structures of patients, and can be used not only for structural heart diseases, but also for the respiratory system, peripheral blood vessels, fistulas or cavities without blood passing through. BRIEF DESCRIPTION OF THE DRAWINGS

[0064] FIG1 is a schematic structural diagram of a blocking device provided in Example 1 of the present invention, wherein the blocking modules of the blocking device are assembled into one piece through a connecting portion;

[0065] FIG2 is a schematic structural diagram of a blocking device provided in Example 1 of the present invention, wherein each blocking module is separated;

[0066] FIG3 is a schematic cross-sectional view of a first connecting member provided in Example 1 of the present invention;

[0067] FIG4 is a schematic cross-sectional view of a second connecting member provided in Example 1 of the present invention;

[0068] FIG5 is a cross-sectional schematic diagram of a connecting portion provided in Example 1 of the present invention, wherein a first connecting member and a second connecting member are assembled together;

[0069] FIG6 is a cross-sectional schematic diagram of the connecting portion provided in Example 1 of the present invention, wherein the first connecting member and the second connecting member are separated;

[0070] FIG7 is a schematic structural diagram of a connecting portion provided in Example 1 of the present invention, wherein the first connecting member and the second connecting member are separated;

[0071] FIG8 is a schematic structural diagram of a first connecting member provided in Example 1 of the present invention;

[0072] FIG9 is a schematic structural diagram of a blocking device provided in Example 2 of the present invention, wherein the blocking modules of the blocking device are assembled into one piece through a connecting portion;

[0073] FIG10 is a schematic structural diagram of a blocking device provided in Example 2 of the present invention, wherein each blocking module is disassembled;

[0074] FIG11 is a schematic structural diagram of a connecting portion provided in Example 2 of the present invention, wherein the first connecting member and the second connecting member are separated;

[0075] FIG12 is a cross-sectional view of a connecting portion provided by Example 2 of the present invention, wherein the first connecting member and the second connecting member are separated;

[0076] FIG13 is a cross-sectional schematic diagram of a first connecting member provided in Example 2 of the present invention;

[0077] FIG14 is a cross-sectional schematic diagram of a second connecting member provided in Example 2 of the present invention;

[0078] FIG15 is a schematic structural diagram of a blocking device provided in Example 3 of the present invention, wherein the blocking modules of the blocking device are assembled into one piece through a connecting portion;

[0079] FIG16 is a schematic structural diagram of a blocking device provided in Example 3 of the present invention, wherein each blocking module is separated;

[0080] FIG17 is a schematic structural diagram of a connecting portion provided in Example 3 of the present invention, wherein the first connecting member and the second connecting member are separated;

[0081] FIG18 is a cross-sectional view of a connecting portion provided by Example 3 of the present invention, wherein the first connecting member and the second connecting member are separated;

[0082] FIG19 is a cross-sectional view of a connecting portion provided in Example 3 of the present invention, wherein a first connecting member and a second connecting member are assembled together;

[0083] FIG20 is a cross-sectional schematic diagram of a first connecting member provided in Example 3 of the present invention;

[0084] FIG21 is a cross-sectional schematic diagram of a second connecting member provided in Example 3 of the present invention;

[0085] FIG22 is a schematic structural diagram of a blocking device provided in Example 4 of the present invention, wherein the blocking modules of the blocking device are assembled into one piece through a connecting portion;

[0086] FIG23 is a schematic structural diagram of a blocking device provided in Example 4 of the present invention, wherein each blocking module is separated;

[0087] FIG24 is a schematic structural diagram of a connecting portion provided in Example 4 of the present invention, wherein the first connecting member and the second connecting member are separated;

[0088] FIG25 is a cross-sectional view of a connecting portion provided by Example 4 of the present invention, wherein the first connecting member and the second connecting member are separated;

[0089] FIG26 is a cross-sectional view of a connecting portion provided by Example 4 of the present invention, wherein a first connecting member and a second connecting member are assembled together;

[0090] FIG27 is a schematic structural diagram of a blocking device provided in Example 5 of the present invention, wherein the blocking modules of the blocking device are assembled into one piece through a connecting portion;

[0091] FIG28 is a schematic structural diagram of a blocking device provided in Example 5 of the present invention, wherein each blocking module is disassembled;

[0092] FIG29 is a schematic structural diagram of a connecting portion provided in Example 5 of the present invention, wherein the first connecting member and the second connecting member are separated;

[0093] FIG30 is a schematic cross-sectional view of a first connecting member provided in Example 5 of the present invention;

[0094] FIG31 is a cross-sectional schematic diagram of a second connecting member provided in Example 5 of the present invention;

[0095] FIG32 is a cross-sectional view of a connecting portion provided in Example 5 of the present invention, wherein a first connecting member and a second connecting member are assembled together;

[0096] FIG33 is a schematic structural diagram of a blocking device provided in Example 6 of the present invention, wherein the blocking modules of the blocking device are assembled into one piece through a connecting portion;

[0097] FIG34 is a schematic structural diagram of a blocking device provided in Example 6 of the present invention, wherein each blocking module is separated;

[0098] FIG35 is a schematic structural diagram of a connecting portion provided in Example 6 of the present invention, wherein the first connecting member and the second connecting member are separated;

[0099] FIG36 is a cross-sectional schematic diagram of a first connecting member provided in Example 6 of the present invention;

[0100] FIG37 is a cross-sectional schematic diagram of a second connecting member provided in Example 6 of the present invention;

[0101] FIG38 is a cross-sectional view of a connecting portion provided by Example 6 of the present invention, wherein a first connecting member and a second connecting member are assembled together;

[0102] FIG39 is a schematic structural diagram of a blocking device provided by an embodiment of the present invention, wherein the blocking modules of the blocking device are assembled into one piece through a connecting portion;

[0103] FIG40 is a schematic structural diagram of another blocking device provided by an embodiment of the present invention, wherein the blocking modules of the blocking device are assembled into one piece through a connecting portion;

[0104] FIG41 is a schematic structural diagram of another blocking device provided by an embodiment of the present invention, wherein the blocking modules of the blocking device are assembled into one piece through a connecting portion;

[0105] FIG42 is a schematic diagram of a side view of a blocking device provided by an embodiment of the present invention;

[0106] FIG43 is a schematic diagram of the blocking device provided by an embodiment of the present invention from another side view angle.

[0107] Description of reference numerals:

[0108] Blocking device 1, blocking module 10, connecting portion 20, first connecting member 101, second connecting member 201, telescopic portion 110, first limiting portion 210, first accommodating cavity 121, protruding member 122, connecting rod 123, first elastic piece 124, first end wall 125, first end surface 1251, first body 126, first groove 221, second end wall 222, second body 223, second end surface 2231, second accommodating cavity 131, second elastic piece 132, protrusion 133, abutting section 134, third end wall 135, third body 136, third end surface 1361, second groove 231, chamfer 232, fourth end wall 233, fourth end surface 2331, fourth body 234, locking portion 140, second limiting portion 240, protrusion 151, fifth end wall 152, fifth body 153, fifth end surface 1531, guide section 251, transition section 252, limiting section 253, abutting plate 254, third elastic member 255, third accommodating chamber 256, sixth end wall 257, sixth body 258, internal thread 161, external thread 261, seventh end wall 262, seventh body 263, plug-in portion 171, gap 172, first sheet 173, first limiting protrusion 174, eighth end wall 175, eighth end surface 1751, eighth body 176, fourth accommodating chamber 271, Three grooves 272, ninth end wall 273, ninth body 274, ninth end face 2741, first joining portion 181, opening 182, second piece 183, second limiting protrusion 184, tenth end wall 185, tenth end face 1851, tenth body 186, second joining portion 281, joining groove 282, fourth groove 283, eleventh end wall 284, eleventh end face 2841, eleventh body 285, connecting piece 30. DETAILED DESCRIPTION

[0109] The present invention is further described below by way of examples, but the present invention is not limited to the scope of the examples.

[0110] An embodiment of the present invention provides a combined sealing device 1, which is a multi-section combined structure. The sealing device 1 includes a connecting portion 20 and at least two sealing modules 10; the at least two sealing modules 10 are arranged in sequence at intervals, and a connecting portion 20 is provided between two adjacent sealing modules 10; the connecting portion 20 includes at least two connecting members, the at least two connecting members include a first connecting member 101 and a second connecting member 201, the first connecting member 101 and the second connecting member 201 are respectively connected to the two adjacent sealing modules 10, and the first connecting member 101 and the second connecting member 201 are connected.

[0111] The occluding device 1 has a multi-stage structure, meaning that the occluding modules 10 are composed of multiple relatively independent components that do not affect each other. This means that a change in the shape of one occluding module 10 does not cause changes in the shape of adjacent occluding modules 10. This eliminates the prior art practice of occluding modules 10 easily interfering with each other, which could easily cause the distal occluding module 10 to deform into a gourd-shaped shape with an increased axial length. This avoids damage to the implanted site caused by the increased axial length of the occluding module 10, thereby increasing the safety and effectiveness of the occlusion. At least two occluding modules 10 are spaced apart in sequence to match the occlusion of anatomical defects and enhance the occlusion effect. The blocking modules 10 are connected by a first connecting member 101 and a second connecting member 201. During surgery, blocking modules 10 of appropriate structure and size are selected as needed, and connected into an integrated blocking device 1 through the connecting part. The blocking device 1 is then implanted into the part that needs to be blocked during surgery. In this way, the blocking device 1 can adapt to defects in different anatomical structures, allowing the blocking module 10 to be more closely attached to the defect in the anatomical structure.

[0112] Through the occlusion device 1 of this solution, doctors can freely combine occlusion modules 10 of different structures and sizes according to the structure and size of the anatomical defect, and set the number of occlusion modules 10, thereby increasing the matching degree and occlusion stability of the occlusion device 1 and improving the occlusion effect. At the same time, it can also reduce the probability of replacing the occlusion device 1 during surgery, reduce the patient's bleeding time, and reduce the difficulty of the doctor in selecting the occlusion device 1. The operation is simpler and more reliable, increasing the flexibility of the surgery and improving the success rate of the surgery. In addition, it is no longer necessary to prepare a large number of occlusion devices 1 of different specifications. Instead, occlusion modules 10 and connecting parts of different structures and sizes are independently manufactured first, and then, according to the structure and size of the anatomical defect actually measured by the patient, more matching occlusion modules 10 and connecting parts are reassembled to form a combined occlusion device 1. In this way, a single device can cover the treatment of a variety of anatomical defects, which can not only improve the matching degree of the occlusion device 1 with the patient's cardiac anatomical defect, but also increase the flexibility of the surgery and improve the success rate of the surgery. The occlusion device 1 of the present application can be used to treat defects in various anatomical structures of patients, and can be used not only for structural heart diseases, but also for the respiratory system, peripheral blood vessels, fistulas or cavities without blood passing through.

[0113] It should be noted that the more occluding modules 10 there are, the more conducive it is for the occluding device to be stably placed in the defect of the anatomical structure. Adding a occluding module 10 is equivalent to increasing the guarantee that the occluding device is stably placed in the defect of the anatomical structure. Even if one occluding module 10 is deformed, resulting in poor occlusion or displacement, the other occluding modules will enable the occluding device to be stably placed in the defect of the anatomical structure and ensure a better occluding effect. Therefore, the occluding device does not need to be provided with barbs to help it be stably placed in the defect of the anatomical structure.

[0114] During specific implementation, the first connecting member 101 and the second connecting member 201 may be directly connected or indirectly connected via other components.

[0115] The blocking module 10 includes one of a disc-shaped structure, a cylindrical structure and a truncated cone-shaped structure.

[0116] When the occlusion module 10 is used to occlude anatomical defects, the end faces of the disc-shaped occlusion module 10 lie on the same plane, making it easier for endothelial cells to crawl over them, accelerating endothelialization and postoperative recovery. Cylindrical or truncated cone-shaped occlusion modules 10 can adapt to the structure of anatomical defects, which helps improve the occlusion effect.

[0117] During specific implementation, the blocking module 10 in the blocking device 1 can adopt one or more of a disc-shaped structure, a cylindrical structure and a truncated cone structure according to needs. Specifically, when applied to patent foramen ovale, the blocking modules 10 in the blocking device 1 can all be disc-shaped structures. When applied to patent ductus arteriosus, the blocking module 10 in the blocking device 1 can adopt a combination of a disc-shaped structure and a truncated cone structure. When applied to blocking the left atrial appendage of the heart, the blocking modules 10 in the blocking device 1 can all be disc-shaped structures, or a combination of a disc-shaped structure and a cylindrical structure. When applied to ventricular septal defect, the blocking module 10 in the blocking device 1 can adopt a combination of a disc-shaped structure and a cylindrical structure. When applied to atrial septal defect, the blocking modules 10 in the blocking device 1 can all be disc-shaped structures.

[0118] As a preferred embodiment, as shown in FIG. 1 to FIG. 43 , the end surface of the blocking module 10 is a plane.

[0119] In another preferred embodiment, the end surface of the blocking module 10 is a curved surface, wherein the curved surface is a curved surface that convexes outward along the axial direction of the blocking module 10, or a curved surface that concave inward along the axial direction of the blocking module 10. In a specific implementation, the end surface of the blocking module 10 convexes outward to form an umbrella-shaped structure, or the end surface of the blocking module 10 contracts inward to form a concave structure.

[0120] The flat end faces of the occlusion module facilitate endothelial cell migration, accelerating endothelialization and postoperative recovery. The outwardly convex surface allows for better shape recovery after release from the delivery sheath, while the inwardly concave surface ensures stable and secure positioning and occlusion during use, making it less susceptible to displacement, such as when occluding an atrial septal defect.

[0121] In specific implementations, the blocking module 10 in the blocking device 1 can adopt any one or more combinations of the above-mentioned disc-shaped, cylindrical, and truncated cone structures. The end surface of a single blocking module 10 can be a flat or curved surface. Those skilled in the art can combine the above-mentioned structures as needed. Therefore, the scope of protection of the present invention should not be limited to the implementations described in this embodiment. The scope of protection of the present invention also includes technical solutions that can be combined as needed by those skilled in the art.

[0122] Specifically, as an embodiment, as shown in FIG. 1 , FIG. 9 , FIG. 15 , FIG. 22 , FIG. 39 and FIG. 40 , the blocking modules 10 in the blocking device 1 are all disc-shaped structures.

[0123] As another embodiment, at least one of the blocking modules 10 in the blocking device 1 is a cylindrical structure, and the rest are disc-shaped structures. As shown in Figure 41, the blocking device 1 includes three blocking modules 10, of which the blocking module 10 on the right is a cylindrical structure, and the other two blocking modules 10 are disc-shaped structures.

[0124] As another embodiment, at least one of the blocking modules 10 in the blocking device 1 is a truncated cone structure, and the rest are disc structures.

[0125] The above provides different structural forms of the occlusion device 1, so as to be adaptable to diverse anatomical structures.

[0126] As shown in FIG. 1 to FIG. 41 , the outer diameter of the connecting portion 20 is smaller than the outer diameter of the blocking module 10 .

[0127] The above structural form can reduce the impact of deformation on the occlusion module 10's shape recovery, making it easier to restore the initial set shape after passing through a thinner delivery sheath. If the occlusion device 1 enters a defect in an anatomical structure with a smaller diameter, the occlusion module 10 can adaptively reduce its radial diameter and adaptively extend its axial direction, thereby better accommodating a longer defect in the human anatomical structure and stably fixing it in the implanted anatomical defect, ensuring a good occlusion effect and long-term implant safety. The connection portion 20 is preferably located at the center of the occlusion module 10.

[0128] As an embodiment, the occlusion modules 10 of the occlusion device 1 have different diameters. The different diameters of the occlusion modules 10 allow them to adapt to the inner diameters of various locations within the anatomical defect (cavity) when used in a defect (cavity) with a varying inner diameter, such as the left atrial appendage, thereby improving implantation and occlusion effectiveness.

[0129] As another embodiment, the occluding modules 10 of the occluding device 1 all have the same diameter. When used in an anatomical defect (cavity) with a constant inner diameter, such as when occluding a section of a blood vessel with a constant inner diameter, the occluding modules 10 can adapt to the inner diameter of each location within the vessel, thereby improving implantation and occlusion effectiveness.

[0130] As another embodiment, the occluding module 10 of the occluding device 1 has a portion of the same diameter and a portion of the same diameter. When the occluding module 10 is used in a defect (cavity) of an anatomical structure with varying inner diameters but with a portion of the same inner diameter, such as the left atrial appendage, the occluding module 10 can adapt to the inner diameter of each portion of the defect (cavity) of the anatomical structure, thereby improving the implantation and occlusion effects.

[0131] As shown in FIG1 and FIG2 , the blocking device 1 has three blocking modules 10 . The blocking modules 10 are all disc-shaped structures. The three blocking modules 10 are connected at their centers by the connecting portion 20 described in the following embodiment 1. The diameter gradient of the three blocking modules 10 decreases.

[0132] As shown in FIG9 and FIG10 , the blocking device 1 has three blocking modules 10 . The blocking modules 10 are all disc-shaped structures. The three blocking modules 10 are connected at their centers by the connecting portion 20 described in the following embodiment 2. The diameter gradient of the three blocking modules 10 decreases.

[0133] As shown in FIG15 and FIG16 , the blocking device 1 has three blocking modules 10 , each of which is a disc-shaped structure. The three blocking modules 10 are connected at their centers by a connecting portion 20 in the following embodiment 3, and the diameter gradient of the three blocking modules 10 decreases.

[0134] As shown in Figures 22 and 23, the blocking device 1 has three blocking modules 10. The blocking modules 10 are all disc-shaped structures. The three blocking modules 10 are connected at their centers by the connecting portion 20 described in the following embodiment 4. The diameter gradient of the three blocking modules 10 decreases.

[0135] As shown in Figures 27 and 28, the blocking device 1 has three blocking modules 10. The blocking modules 10 are all disc-shaped structures. The three blocking modules 10 are connected at their centers by the connecting portion 20 described in the following embodiment 5. The diameter gradient of the three blocking modules 10 decreases.

[0136] As shown in Figures 33 and 34, the blocking device 1 has three blocking modules 10. The blocking modules 10 are all disc-shaped structures. The three blocking modules 10 are connected at their centers by the connecting portion 20 described in the following embodiment 6. The diameter gradient of the three blocking modules 10 decreases.

[0137] As shown in Figure 39, the blocking device 1 has five blocking modules 10, and the blocking modules 10 are all disc-shaped structures. The five blocking modules 10 are connected at their centers by the connecting part 20 in the following embodiment 1. The diameters of the five blocking modules 10 are all different. Specifically, from one end to the other end of the blocking device 1, the diameter of the blocking module 10 changes from large to small, then large, and then small.

[0138] As shown in Figure 40, the blocking device 1 has four blocking modules 10, and the blocking modules 10 are all disc-shaped structures. The four blocking modules 10 are connected at their centers by the connecting part 20 in the following embodiment 2. The diameters of the four blocking modules 10 are all different. Specifically, from one end to the other end of the blocking device 1, the diameter of the blocking module 10 changes from large to small and then to large.

[0139] As shown in Figure 41, the blocking device 1 has three blocking modules 10, two of which are disc-shaped structures, and one blocking module 10 is a cylindrical structure. The three blocking modules 10 are connected at their centers by the connecting portion 20 in the following embodiment 3. The diameters of the three blocking modules 10 are all different. Specifically, from one end to the other end of the blocking device 1, the two disc-shaped blocking modules 10 and the cylindrical blocking module 10 are arranged in sequence, and the diameters of the three blocking modules 10 become smaller in sequence.

[0140] In a preferred embodiment, the end surface of the occluding device 1 closes into a smooth, flat disk-like surface. This end surface is used to connect to a delivery device for transporting the occluding device 1. This smooth, flat disk-like surface facilitates endothelial cell migration, accelerating endothelialization and postoperative recovery. As shown in Figures 39-41, both end surfaces of the occluding device 1 close into a smooth, flat disk-like surface, with no external protrusions.

[0141] As another preferred embodiment, the end face of the blocking device 1 is provided with a connector 30, wherein the end face of the blocking device 1 is used to connect to a conveying device that transports the blocking device 1. The end face of the blocking device 1 is provided with a connector 30, which can facilitate connection with the conveying device. As shown in Figure 1, the left end face of the blocking device 1 is provided with a connector 30, which can be connected to the conveying device. As shown in Figures 42 and 43, which are two side views of the blocking device 1, the blocking module 10 has a mesh structure.

[0142] As a preferred embodiment, the axial length of the occlusion device 1 is configured to adapt to the anatomical defect being occluded. The occlusion modules 10 and connectors 20 can be independently manufactured with different axial lengths. Then, based on the structure and size of the patient's actual anatomical defect, the appropriate occlusion module 10 and connector 20 can be selected and combined, thereby enabling the occlusion device 1 to adapt to the diverse anatomical structures of the patient.

[0143] In a specific implementation, the first connector 101 and the second connector 201 of different axial lengths can be pre-combined into one with the corresponding blocking module 10, wherein the structure of the blocking module 10 can be selected from a disc shape, a cylindrical shape, a truncated cone shape or other suitable shapes, and the end face of the blocking module 10 can be selected from a plane, a curved surface or other forms of surface. The end face of the blocking module 10 can be connected to the first connector 101 or the second connector 201, and the axial length of the first connector 101 or the second connector 201 can also be configured to a suitable length.

[0144] As a preferred embodiment, the connection portion 20 is connected by means of a chiseling, a mortise and tenon joint, or a latch. The connection portion 20 can be connected by any of the above methods. In actual implementation, the corresponding connection method can be selected according to needs, thereby improving the convenience and flexibility of implementation.

[0145] The occlusion device 1 is used to treat defects in a variety of patient anatomical structures. In practice, the anatomical structures of patients are diverse. The occlusion device 1 of the present invention can be flexibly assembled using prefabricated occlusion modules 10 to adapt to different anatomical structures, improving the matching degree, increasing surgical flexibility, and improving the success rate of the surgery.

[0146] Preferably, the occlusion device 1 is applied to structural heart disease, respiratory system, peripheral blood vessels, fistulas or cavities without blood flowing through them.

[0147] When applied to the left atrial appendage, the left atrial appendage can be regarded as a kind of anatomical defect. Since there are many kinds of left atrial appendage structures, the inner diameters of the cavities at various locations in the left atrial appendage are also different. The structure of the left atrial appendage and the inner diameters of the cavities at various locations are determined through preoperative examinations to select appropriate occlusion modules 10 for assembly to meet the diverse needs of left atrial appendage occlusion. By abutting multiple occlusion modules 10 against the inner diameters of the left atrial appendage at various locations, a stable connection and fixation is formed with the inner wall of the left atrial appendage. The occlusion device 1 will not shift and fall off in the heart, and the occlusion effect can also be improved.

[0148] In actual implementation, the left atrial appendage has various structural forms, and may also be a special-shaped structure, and its size, depth, etc. are all different. The occlusion device 1 of the present invention can be used to occlude the left atrial appendage. By providing multiple occlusion modules 10 and configuring the structure and size of the occlusion modules 10 according to the structure and size of the left atrial appendage, effective occlusion of the left atrial appendage can be achieved. Preferably, the occlusion device 1 used for left atrial appendage occlusion has at least three occlusion modules 10.

[0149] When applied to a blood vessel, a blocking module 10 of corresponding structure and size can be matched according to the structure and size of the blood vessel and combined to form a corresponding blocking device 1, thereby improving the blocking effect.

[0150] When applied to other cavities where no blood flows, the blocking module 10 of corresponding structure and size can be matched according to the structure and size of the other cavities and combined to form a corresponding blocking device 1, thereby improving the blocking effect.

[0151] In a specific implementation, the first connecting member 101 and the second connecting member 201 of the connecting portion 20 can adopt various different structural forms. For example, the first connecting member 101 and the second connecting member 201 can be connected to each other by relative movement along the axial direction, or by relative rotation, or other suitable methods.

[0152] As a feasible embodiment, as shown in Figures 1-8, 9-14, 27-32, and 33-38, the first connector 101 and the second connector 201 move relative to each other along the axial direction to achieve connection. The axial direction is the axis direction of the blocking module 10, that is, the axial direction of the first connector 101 or the axial direction of the second connector 201.

[0153] Specifically, as shown in Figures 1 to 8 and Figures 9 to 14, the first connecting member 101 and the second connecting member 201 are connected in an interlocking manner. The first connecting member 101 is provided with a telescopic portion 110, and the second connecting member 201 has a first limiting portion 210. The second connecting member 201 moves along the axial direction of the first connecting member 101 and compresses the telescopic portion 110 along the radial direction of the first connecting member 101; until the telescopic portion 110 restores its predetermined shape and extends into the first limiting portion 210, so that the second connecting member 201 is connected to the first connecting member 101.

[0154] The second connector 201 and the first connector 101 can be connected to each other by relative movement along their axial directions. In the process of the second connector 201 and the first connector 101 approaching each other, the second connector 201 can first compress the telescopic portion 110. When it moves to a position where the first limiting portion 210 is opposite to the telescopic portion 110, the telescopic portion 110 can restore a predetermined shape and extend into the first limiting portion 210, thereby achieving mutual fixation between the first connector 101 and the second connector 201. This type of connecting portion 20 is simple to operate, and when the first connector 101 and the second connector 201 are connected, a stable connection can be formed, thereby improving the reliability of the occlusion device 1 after implantation in the patient's body.

[0155] Specifically, as shown in Figures 27 to 32, the first connecting member 101 and the second connecting member 201 are connected by mortise and tenon methods. The first connecting member 101 is provided with a plug-in portion 171, and the second connecting member 201 is provided with a fourth accommodating cavity 271. The first connecting member 101 moves along the axial direction of the second connecting member 201, and the plug-in portion 171 extends into the fourth accommodating cavity 271 until the plug-in portion 171 moves to a predetermined position and is restricted, so that the second connecting member 201 is connected to the first connecting member 101.

[0156] The second connector 201 and the first connector 101 can be connected to each other by relative movement along their axial direction. The plug portion 171 extends into the fourth accommodating cavity 271 until the plug portion 171 moves to a predetermined position and is restrained, thereby securing the first connector 101 and the second connector 201 to each other. This type of connector 20 is simple to operate, and when the first connector 101 and the second connector 201 are connected, a stable connection is formed, improving the safety and reliability of the occlusion device 1 after implantation in a patient.

[0157] Specifically, as shown in Figures 33 to 38, the first connecting member 101 and the second connecting member 201 are connected by means of a pin. The first connecting member 101 is provided with a first engaging portion 181, and the second connecting member 201 is provided with a second engaging portion 281. The first connecting member 101 moves along the axial direction of the second connecting member 201 until the first engaging portion 181 and the second engaging portion 281 are connected and restricted to each other, so that the second connecting member 201 is connected to the first connecting member 101.

[0158] The second connector 201 and the first connector 101 can be connected to each other by relative movement along their axial direction. The first engaging portion 181 and the second engaging portion 281 are connected and restrained, thereby achieving mutual fixation between the first connector 101 and the second connector 201. This type of connecting portion 20 is simple to operate, and when the first connector 101 and the second connector 201 are connected, a stable connection is formed, thereby improving the safety and reliability of the occlusion device 1 after implantation in the patient.

[0159] As another feasible embodiment, as shown in Figures 15-21 and 22-26, the first connecting member 101 and the second connecting member 201 rotate relative to each other around an axis to achieve a rotational connection. The axis is the axis of the blocking module 10, that is, the axis of the first connecting member 101 or the axis of the second connecting member 201.

[0160] Specifically, the first connecting member 101 has a locking portion 140, and the second connecting member 201 has a second limiting portion 240. The second connecting member 201 rotates around the axis of the first connecting member 101, and the locking portion 140 moves in the second limiting portion 240 until it is locked in the second limiting portion 240, so that the second connecting member 201 is connected to the first connecting member 101.

[0161] The second connecting member 201 rotates around the axis of the first connecting member 101 to achieve a mutual rotational connection between the two. This connection method is simple and easy to operate. Moreover, when the first connecting member 101 and the second connecting member 201 are connected, a stable connection is formed, which improves the reliability of the occlusion device 1 after it is implanted in the patient's body.

[0162] The multiple blocking modules 10 within the blocking device 1 may also have different structural forms. The following embodiments provide some feasible implementations, but the scope of protection of the present invention should not be limited to the following implementations. The following embodiments provide various specific implementations of the connection portion 20. During implementation, the connection between the multiple blocking modules 10 in the blocking device 1 may utilize one or more of the above connection portions 20. That is, the connection portion 20 in the blocking device 1 may be any one of the following embodiments, or may include multiple of the following embodiments.

[0163] Example 1

[0164] This embodiment provides a blocking device comprising a plurality of independent blocking modules 10, which are connected by a connecting portion 20. The blocking device is formed by assembling the plurality of independent blocking modules 10 together. The first connecting member 101 and the second connecting member 201 of the connecting portion 20 are connected by relative movement along the axial direction. As shown in Figures 1-8, the second connecting member 201 is sleeved on the outside of the first connecting member 101.

[0165] The first limiting portion 210 is a first groove 221 recessed from the inner side wall of the second connecting member 201;

[0166] A first accommodating cavity 121 is provided in the first connecting member 101, and the telescopic portion 110 is provided in the first accommodating cavity 121; the telescopic portion 110 includes a protruding member 122 passing through the side wall of the first accommodating cavity 121, and the protruding member 122 is radially extended along the first connecting member 101. After the protruding member 122 extends out of the side wall of the first accommodating cavity 121, it is connected to the first groove 221.

[0167] The second connector 201 is sleeved onto the outside of the first connector 101, enhancing the structural strength of the connector 20 and making the axial dimensions of the connector 20 more compact, shortening the distance between adjacent blocking modules 10 and improving the blocking effect. The first accommodating cavity 121 accommodates the telescopic portion 110, allowing the extension member 122 of the telescopic portion 110 to extend or retract relative to the sidewall of the first accommodating cavity 121, thereby achieving axial connection between the second connector 201 and the first connector 101.

[0168] In a specific implementation, as shown in Figures 6 and 7 , the outer contours of the first connector 101 and the second connector 201 are both roughly cylindrical. As shown in Figures 3 , 6 , 7 , and 8 , the first connector 101 includes a first end wall 125 and a first body 126 . The first end wall 125 is connected to one end of the first body 126 and extends outward in the radial direction of the first body 126 . The first accommodating cavity 121 passes through the first end wall 125 and the first body 126 . The first end wall 125 is used to connect to the blocking module 10 . The extension 122 passes through the first body 126 and is retractable relative to the first body 126 . Furthermore, the extension 122 and the first end wall 125 are located at opposite ends of the first body 126 .

[0169] As shown in Figures 4, 6, and 7, the second connector 201 includes a second end wall 222 and a second body 223. The second end wall 222 is connected to one end of the second body 223, and the two form a cylindrical structure. As shown in Figure 5, the second body 223 can be sleeved on the outside of the first body 126. The second end surface 2231 of the second body 223 can contact the first end surface 1251 of the first end wall 125. The outer wall of the second body 223 can be flush with the outer edge of the first end wall 125. Therefore, after the first connector 101 and the second connector 201 are connected, the connecting portion 20 can form a uniform outer surface.

[0170] In addition, the second connecting member 201 and the first connecting member 101 are arranged in a sleeve manner, which is also conducive to controlling the radial and axial dimensions of the connecting portion 20. During surgery, the occluding device 1 needs to be first received into a thinner delivery sheath, enter the thinner blood vessels of the human body through the delivery sheath, and be delivered to the surgical site. When the occluding device 1 reaches the appropriate surgical position, it is pushed out and released from the delivery sheath. By controlling the radial and axial dimensions of the connecting portion 20, the influence of the connecting portion 20 on the shape recovery of the occluding module 10 can be reduced, so that the disc spacing can be controlled, better adapting to the structure and size of the defect of the human anatomical structure to be repaired, and thus matching it.

[0171] Furthermore, as shown in Figures 3 and 4, the extension 122 is generally cylindrical, with its protruding end having a chamfered, hemispherical structure. The first groove 221, in its axial cross-section, has a size that gradually decreases from its maximum inner diameter toward its bottom ends on both sides. As shown in Figure 5, when the extension 122 is inserted into the first groove 221, the protruding end of the extension 122 can smoothly enter the first groove 221 and contact the groove surface of the first groove 221, thereby connecting and securing the first connector 101 to the second connector 201.

[0172] As shown in Figures 3 and 6, the telescopic portion 110 further includes a first elastic member and a connecting rod 123. The connecting rod 123 is arranged radially along the first connecting member 101 and is connected to the sidewall of the first accommodating cavity 121. The first elastic member includes a first elastic sheet 124. One end of the first elastic sheet 124 is connected to the connecting rod 123. The first elastic sheet 124 can be fixed around the connecting rod 123 or directly fixed to the surface of the connecting rod 123 facing the protruding member 122. The first elastic sheet 124 extends toward the inner sidewall of the first accommodating cavity 121. The protruding member 122 is connected to the extended end of the first elastic sheet 124.

[0173] When the first elastic member is acted upon by the second connecting member 201, it can be compressed so that the protruding member 122 can be retracted to the inside of the outer surface of the first connecting member 101, and can also store force to provide a force that causes the protruding member 122 to extend beyond the outer surface of the first connecting member 101. When the second connecting member 201 is moved into position, the protruding member 122 can automatically extend from the side wall of the first body 126 and into the first groove 221, thereby achieving a locked connection between the two connecting members. Furthermore, the connecting rod 123 and the protruding member 122 can connect the two ends of the first elastic piece 124 to the first connecting member 101.

[0174] As shown in Figures 6 and 8 , the ends of the connecting rod 123 are respectively connected to the first body 126, which can enhance the stability of the connecting rod 123. As shown in Figure 3 , the connecting rod 123 is positioned near the first end wall 125, and the extension 122 is located at the ends of the first body 126. The ends of the first elastic piece 124 are respectively connected to the connecting rod 123 and the extension 122, allowing the first elastic piece 124 to be arranged along the axial direction of the first connecting member 101, with a longer structural dimension, which can provide better elastic force when the extension 122 is extended or retracted.

[0175] In a specific implementation, the number of the first elastic pieces 124 can be one or more. When there are multiple first elastic pieces 124 , the reliability of the connection between the two connectors can be improved. The multiple first elastic pieces 124 can be evenly arranged around the circumference of the first connector 101 .

[0176] As shown in Figures 3 and 6, the first elastic member includes two first elastic pieces 124, which are connected and V-shaped; the connection between the two first elastic pieces 124 is connected to the connecting rod 123, and the extended ends of the two first elastic pieces 124 are provided with protruding pieces 122.

[0177] By using two or more first elastic pieces 124, the number of connection points between the first elastic member and the second connecting member 201 can be increased, making the force applied to the two connecting members more balanced and improving the stability of the connection between the two. In addition, the two first elastic pieces 124 are arranged in a V-shape, which facilitates the connection of the first elastic member to the first connecting member 101 via the connecting rod 123. In addition, both ends of the first elastic member can be affected by the second connecting member 201, making the overall compression of the first elastic member more balanced, improving the movement effect, and making the first elastic member more flexible and free.

[0178] As shown in Figures 3, 6, and 8, the connection between the two first elastic pieces 124 is arc-shaped and sleeved onto the outer wall of the connecting rod 123. The first elastic piece 124 extends from this connection along the axial direction of the first connector 101 toward the sidewall of the first accommodating cavity 121. The extension piece 122 is connected to the extended end of the first elastic piece 124. The two first elastic pieces 124 are arranged opposite each other, and the connecting rod 123 is located at the axis of the first connector 101, so that the telescopic portion 110 is arranged symmetrically.

[0179] As shown in Figures 4 and 6, the first limiting portion 210 is an annular groove arranged around the circumference of the second connecting member 201. When the second connecting member 201 is connected to the first connecting member 101, the two are axially aligned and close to each other, without the need for circumferential alignment, thereby improving operational convenience.

[0180] Example 2

[0181] This embodiment provides a blocking device comprising a plurality of independent blocking modules 10, which are connected by a connecting portion 20. The blocking device is formed by assembling the plurality of independent blocking modules 10. The first connecting member 101 and the second connecting member 201 of the connecting portion 20 are connected by relative movement along the axial direction. As shown in Figures 9-14, the first connecting member 101 is provided with a second accommodating cavity 131, and the second connecting member 201 extends into the second accommodating cavity 131.

[0182] In practice, the second connector 201 in Example 1 is sleeved on the outside of the first connector 101. In this embodiment, the first connector 101 is sleeved on the outside of the second connector 201. This can enhance the structural strength of the connector 20, make the axial dimension of the connector 20 more compact, shorten the distance between two adjacent occluding modules 10, and improve the occluding effect. Furthermore, it is also beneficial to control the radial dimension of the connector 20, thereby facilitating surgery and avoiding affecting the deformation recovery of the occluding module 10, so that the occluding module 10 can more easily return to its original shape after being released from the thinner delivery sheath.

[0183] As shown in Figures 11-14, the first limiting portion 210 is a second groove 231 recessed from the outer wall of the second connecting member 201. The telescopic portion 110 is located within the second accommodating cavity 131 and connected to the inner wall of the second accommodating cavity 131. The telescopic portion 110 includes a protrusion 133 that protrudes into the interior of the second accommodating cavity 131 and abuts against the second groove 231. The telescopic portion 110 has a protrusion 133 that protrudes into the interior of the second accommodating cavity 131 and can be compressed and abut against the second groove 231. This connection portion 20 has a simple structure and a stable connection.

[0184] In a specific implementation, as shown in Figures 11, 12, and 13, the outer contour of the first connector 101 is roughly cylindrical and includes a third end wall 135 and a third body 136. The third end wall 135 is connected to one end of the third body 136. The second accommodating cavity 131 is provided inside the third end wall 135 and forms a cylindrical structure. The telescopic portion 110 is provided on the inner side wall of the third body 136, and the protrusion 133 is arranged near the opening of the second accommodating cavity 131. As shown in Figures 11, 12, and 14, the second connector 201 includes a fourth end wall 233 and a fourth body 234. The fourth end wall 233 is connected to one end of the fourth body 234, wherein the fourth body 234 is roughly a solid structure, and the second groove 231 is provided on the circumferential side wall of the fourth body 234. The third end wall 135 and the fourth end wall 233 are respectively used to connect to the corresponding blocking module 10. When the first connecting member 101 is connected to the second connecting member 201, the third body 136 can be sleeved on the outside of the fourth body 234, the third end face 1361 of the third body 136 can contact the fourth end face 2331 of the fourth end wall 233, and the telescopic part 110 arranged in the third body 136 can abut against the second groove 231 of the fourth body 234.

[0185] As shown in Figures 12 and 13, the telescopic portion 110 is a second elastic piece 132, which is arranged along the axial direction of the first connector 101. The second elastic piece 132 abuts the second accommodating cavity 131 at both ends of the first connector 101 in the axial direction, and the middle portion of the second elastic piece 132 protrudes toward the second accommodating cavity 131 to form a protrusion 133. The telescopic portion 110 is an elastic piece structure, with both ends abutting the second accommodating cavity 131 and the middle portion protruding toward the interior of the second accommodating cavity 131. When the second connector 201 moves toward the first connector 101, the protrusion 133 can be compressed by the second connector 201. When the second connector 201 moves to the second groove 231 and is opposite the protrusion 133, the protrusion 133 recovers and abuts the second groove 231.

[0186] As shown in Figure 13, the inner sidewall of the third body 136 is provided with an axially extending receiving groove. The depth of this receiving groove extending into the second receiving cavity 131 is approximately equal to the thickness of the second elastic piece 132, and the length of this receiving groove along the axial direction of the third body 136 is approximately equal to the length of the second elastic piece 132. The second elastic piece 132 has straight abutment sections 134 at each end, each of which is disposed within the receiving groove. Preferably, the abutment section 134 near the opening of the second receiving cavity 131 is lower than the receiving groove to prevent obstruction between the fourth body 234 and the second elastic piece 132 during movement.

[0187] As shown in Figures 12 and 13, at the axial direction of the first connector 101, the cross-section of the protrusion 133 is triangular, and the tip of the protrusion 133 is close to the second connector 201. The triangular cross-section of the protrusion 133 makes it easier for the second connector 201 to be pushed into the second accommodating cavity 131 of the first connector 101, and the protrusion 133 can be easily compressed and can limit the second connector 201 in the axial direction. In addition, the protrusion 133 can have a longer limiting surface that contacts the second groove 231, thereby improving the connection between the two connectors and making the connection more stable.

[0188] As shown in Figures 12 and 13, the protrusion 133 extends a certain distance from the abutment section 134 near the third end wall 135 into the interior of the second accommodating cavity 131, and then extends a certain distance toward the side wall of the second accommodating cavity 131, and is connected to the abutment section 134 near the opening of the second accommodating cavity 131; wherein, the extension length of the protrusion 133 near the third end wall 135 is greater than the extension length near the opening, so that the tip of the protrusion 133 is close to the second connecting member 201. When the second connecting member 201 is connected to the second accommodating cavity 131, it can provide a larger limiting area and improve the stability of the connection.

[0189] As shown in Figures 11, 12, and 14, the second groove 231 is also triangular in shape at the axial direction of the second connector 201. The shape of the second groove 231 matches the shape of the protrusion 133, thereby improving the stability of the connection. In addition, the second groove 231 is circumferentially arranged around the outer side of the fourth body 234, thereby improving the convenience of operation.

[0190] As shown in Figures 11, 12, and 14, the end wall of the second connector 201 is provided with a chamfer 232. This not only facilitates the docking of the second connector 201 with the first connector 101, but also allows the chamfer 232 to easily penetrate the tip of the protrusion 133 when the second connector 201 compresses the protrusion 133 of the first connector 101, thereby facilitating compression of the protrusion 133 and improving connection reliability.

[0191] The fourth body 234 has an edge provided with a chamfer 232, which can reduce the size of the end face of the fourth body 234. When the second connecting member 201 extends into the first connecting member 101, the end face of the fourth body 234 with the chamfer 232 can more easily dock with the position of the protrusion 133, thereby gradually compressing the protrusion 133 and improving the convenience of connection.

[0192] Example 3

[0193] This embodiment provides a blocking device comprising multiple independent blocking modules 10, which are connected by a connecting portion 20. The multiple independent blocking modules 10 are assembled together to form the blocking device. The first connecting member 101 and the second connecting member 201 of the connecting portion 20 are rotatably connected by relative rotation about an axis. As shown in Figures 15-21, the locking portion 140 is a protrusion 151 that protrudes radially from the first connecting member 101.

[0194] The second limiting portion 240 includes a guide section 251, a transition section 252 and a limiting section 253 that are connected in sequence. The guide section 251 extends from the end of the second connecting member 201 along the axial direction of the second connecting member 201, the transition section 252 extends along the circumferential direction of the second connecting member 201, and the limiting section 253 extends along the axial direction of the second connecting member 201 and is opposite to the axial extension direction of the guide section 251.

[0195] The protrusion 151 can move along the axial direction of the second connecting member 201 in the guide section 251, then move along the circumferential direction of the second connecting member 201 in the transition section 252, and then move along the axial direction of the second connecting member 201 to the limiting section 253, thereby realizing the connection between the first connecting member 101 and the second connecting member 201 and limiting the axial and radial positions of the first connecting member 101. This connection method is simple, and the protrusion 151 and the second limiting portion 240 are provided on the first connecting member 101 and the second connecting member 201 themselves, and the structure is reliable and stable. In addition, the above structure is also easy to disassemble. When the structure and size of the blocking module 10 are not suitable and need to be adjusted, it can be easily disassembled and replaced with a suitable blocking module.

[0196] As shown in Figures 17, 18, and 19, the first connector 101 includes a fifth end wall 152 and a fifth body 153. The fifth end wall 152 is connected to one end of the fifth body 153 and extends outward in the radial direction of the fifth body 153. The fifth end wall 152 is used to connect to the blocking module 10. The protrusion 151 is connected to the outer wall of the fifth body 153 and extends in the radial direction of the fifth body 153. Preferably, as shown in Figures 17 and 18, the protrusion 151 is a cylindrical structure. Protrusions 151 are provided on opposite sides of the fifth body 153. Correspondingly, second limiting portions 240 are provided at corresponding positions on the second connector 201. As shown in Figure 20, the fifth body 153 is a hollow structure. In other embodiments, the fifth body 153 may also be a solid structure.

[0197] As shown in Figures 17, 18, and 21, the second connector 201 includes a sixth end wall 257 and a sixth body 258. The sixth end wall 257 is connected to one end of the sixth body 258 and defines a third accommodating cavity 256, forming a cylindrical structure. The fifth body 153 is capable of extending into the third accommodating cavity 256, and the second stopper 240 is disposed on the sixth body 258. The guide section 251 extends from the end of the sixth body 258 opposite the end 257 toward the end 257 along the axial direction of the sixth body 258. The stopper section 253 also extends along the axial direction of the sixth body 258 but is not connected to the end of the sixth body 258. The transition section 252 extends circumferentially along the sixth body 258 and connects the guide section 251 and the stopper section 253. Therefore, when the projection 151 moves to the stopper section 253, the stopper section 253 can prevent the projection 151 from disengaging from the second connector 201.

[0198] As shown in Figures 17 and 18, the second limiting portion 240 is a limiting hole that passes through the side wall of the second connecting member 201. The limiting hole can limit the position of the protrusion 151, and during the connection operation, it is easy to observe the position of the protrusion 151 in the limiting hole, thereby improving the convenience of operation.

[0199] As shown in Figures 18 and 21, an abutment portion is further provided in the second connector 201. The abutment portion expands and contracts along the axial direction of the first connector 101 and abuts against the fifth end face 1531 of the first connector 101 facing the second connector 201. The abutment portion can provide support in the axial direction of the first connector 101, allowing the protrusion 151 to abut within the limiting section 253, thereby improving the reliability of the connection between the first connector 101 and the second connector 201.

[0200] As shown in FIG. 17 and FIG. 21 , the second limiting portion 240 is located near the opening of the third accommodating cavity 256 , and the abutting portion is provided at the bottom of the third accommodating cavity 256 .

[0201] Furthermore, as shown in Figures 18 and 21, the abutting portion includes an abutting plate 254 and a third elastic member 255. The first connector 101 extends into the second connector 201, and the abutting plate 254 contacts the fifth end face 1531 of the first connector 101. The third elastic member 255 is used to provide a force that causes the abutting plate 254 to abut against the first connector 101. The abutting plate 254 can contact the fifth end face 1531 of the first connector 101 facing the second connector 201, so that the abutting portion forms a stable connection with the fifth end face 1531 of the first connector 101 facing the second connector 201, and the abutting force is provided by the third elastic member 255. The structure is simple, easy to arrange, and can improve the abutting effect.

[0202] As shown in Figure 19, when the first connector 101 is connected to the second connector 201, the fifth body 153 extends into the sixth body 258. As the protrusion 151 moves within the second limiting portion 240, the fifth end surface 1531 of the fifth body 153 can push the abutment plate 254 to move and apply a force to the third elastic member 255. When the protrusion 151 moves to the limiting section 253, the third elastic member 255 can act on the abutment plate 254 to apply a force to the first connector 101, so that the protrusion 151 of the first connector 101 can be confined within the limiting section 253. Preferably, the abutment plate 254 is a flat plate structure. In other embodiments, it can also be an annular structure. The third elastic member 255 is preferably a spring.

[0203] Example 4

[0204] This embodiment provides a blocking device comprising multiple independent blocking modules 10, which are connected by a connecting portion 20. The multiple independent blocking modules 10 are assembled together to form the blocking device. The first connecting member 101 and the second connecting member 201 of the connecting portion 20 are rotatably connected by relative rotation about an axis. Specifically, the locking portion and the second limiting portion are internally threaded and externally threaded, respectively. One of the internal and external threads is provided on the first connecting member 101, and the other is provided on the second connecting member 201.

[0205] As shown in Figures 22-26, the locking portion 140 is an internal thread 161 provided inside the first connecting member 101, and the second limiting portion 240 is an external thread 261 provided on the outer wall of the second connecting member 201. The internal thread 161 and the external thread 261 are used to connect the first connecting member 101 and the second connecting member 201. This connection structure is simple, the connection method is easy to operate, and has good connection stability.

[0206] As shown in Figures 24, 25, and 26, the first connector 101 is generally cylindrical in structure, and the locking portion 140 is an internal thread 161 provided on the inner sidewall of the first connector 101. The second connector 201 includes a seventh end wall 262 and a seventh body 263. The seventh end wall 262 is connected to one end of the seventh body 263, which is a solid structure and is used to connect to the blocking module 10. The second limiting portion 240 is an external thread 261 provided on the outer sidewall of the seventh body 263.

[0207] Example 5

[0208] This embodiment provides a blocking device comprising a plurality of independent blocking modules 10, which are connected by a connecting portion 20. The plurality of independent blocking modules 10 are assembled together to form a blocking device, and the first connecting member 101 and the second connecting member 201 of the connecting portion 20 are connected by relative movement along the axial direction. As shown in Figures 27 to 32, the first connecting member 101 and the second connecting member 201 are connected by a mortise and tenon joint. The first connecting member 101 is provided with a plug-in portion 171, and the second connecting member 201 has a fourth accommodating cavity 271. The first connecting member 101 moves along the axial direction of the second connecting member 201, and the plug-in portion 171 extends into the fourth accommodating cavity 271 until the plug-in portion 171 moves to a predetermined position and is restrained, thereby connecting the second connecting member 201 to the first connecting member 101.

[0209] As shown in Figures 27 and 32, the second connecting member 201 is sleeved on the outside of the first connecting member 101. The second connecting member 201 is sleeved on the outside of the first connecting member 101, which can enhance the structural strength of the connecting portion 20, and can also make the axial dimension of the connecting portion 20 more compact, shorten the distance between two adjacent blocking modules 10, and improve the blocking effect.

[0210] As shown in Figure 30, the plug-in portion 171 is a hollow structure and is provided with a plurality of gaps 172 extending along the axis of the first connector 101. The plurality of gaps 172 are arranged around and form a plurality of first plates 173. A first limiting protrusion 174 is provided on the outside of the plug-in portion 171. Furthermore, a first limiting protrusion 174 is provided on the outside of each first plate 173, and the plurality of first limiting protrusions 174 are located at the same axial position on the first connector 101. As shown in Figure 31, a third groove 272 is provided within the fourth accommodating groove 271, and the third groove 272 is arranged around the inner sidewall of the fourth accommodating groove 271. When the plug-in portion 171 extends into the fourth accommodating cavity 271 and moves to a predetermined position, the plurality of first limiting protrusions 174 are arranged in the third groove 272, thereby connecting the second connector 201 to the first connector 101.

[0211] In a specific implementation, as shown in Figures 29-31 , the outer contours of the first connecting member 101 and the second connecting member 201 are both substantially cylindrical. As shown in Figure 30 , the first connecting member 101 includes an eighth end wall 175 and an eighth body 176 , wherein the eighth end wall 175 is connected to one end of the eighth body 176 .

[0212] As shown in FIG30 , the eighth body 176 is generally cylindrical in structure, and the outer diameter of the eighth body 176 gradually decreases as it moves away from the eighth end wall 175. A gap 172 extends from the end of the eighth body 176 facing away from the eighth end wall 175 along the axis of the eighth body 176, and the gap 172 is elongated. Multiple gaps 172 are arranged around the eighth body 176, forming multiple first sheets 173. As shown in FIG31 , the second connecting member 201 includes a ninth end wall 273 and a ninth body 274. The ninth end wall 273 is connected to one end of the ninth body 274. The two are generally cylindrical in structure and form a fourth accommodating chamber 271. The inner diameter of the ninth body 274 gradually increases as it moves away from the ninth end wall 273. The third groove 272 is arranged around the inner side wall of the ninth body 274.

[0213] As shown in Figure 32, the ninth body 274 can be mounted on the outside of the eighth body 176, the ninth end face 2741 of the ninth body 274 can contact the eighth end face 1751 of the eighth end wall 175, and the outer wall of the ninth body 274 can be flush with the outer edge of the eighth end wall 175, so that after the first connecting member 101 is connected to the second connecting member 201, the connecting part 20 can form a uniform outer surface.

[0214] Example 6

[0215] This embodiment provides a blocking device comprising a plurality of independent blocking modules 10, which are connected by a connecting portion 20. The plurality of independent blocking modules 10 are assembled together to form a blocking device, and the first connecting member 101 and the second connecting member 201 of the connecting portion 20 are connected by relative movement along the axial direction. As shown in Figures 33 to 38, the first connecting member 101 and the second connecting member 201 are connected by a latch. The first connecting member 101 has a first engaging portion 181, and the second connecting member 201 has a second engaging portion 281. The first connecting member 101 moves along the axial direction of the second connecting member 201 until the first engaging portion 181 and the second engaging portion 281 connect and restrict each other, thereby connecting the second connecting member 201 to the first connecting member 101.

[0216] As shown in Figures 35-38 , the outer wall of the second connector 201 is provided with an engagement groove 282 extending from one end of the second connector 201 to the other end, forming a second engagement portion 281. The first engagement portion 181 is a second plate 183 that mates with the engagement groove 282. When the first connector 101 moves along the axis of the second connector 201, the second plate 183 can extend into the engagement groove 282, thereby connecting the second connector 201 to the first connector 101.

[0217] Furthermore, a limiting structure is provided between the first coupling portion 181 and the second coupling portion 281 , and the limiting structure includes a second limiting protrusion 184 and a fourth groove 283 , one of the second limiting protrusion 184 and the fourth groove 283 is provided on the first coupling portion 181 , and the other is provided on the second coupling portion 281 .

[0218] In a specific implementation, as shown in Figure 36 , the first connector 101 includes a tenth end wall 185 and a tenth body 186 . The tenth end wall 185 is connected to one end of the tenth body 186 . An opening 182 extends from the end of the tenth body 186 facing away from the tenth end wall 185 along the axis of the tenth body 186 . The two openings 182 are symmetrically arranged around the tenth body 186 , thereby forming two symmetrically arranged second pieces 183 . Second limiting protrusions 184 are provided on the inner sidewalls of the two second pieces 183 , extending circumferentially along the second piece 183 . Furthermore, as shown in Figure 35 , two second limiting protrusions 184 are spaced apart on the same second piece 183 .

[0219] As shown in Figures 35 and 37, the second connector 201 includes an eleventh end wall 284 and an eleventh body 285. The eleventh end wall 284 is connected to one end of the eleventh body 285, and both are generally cylindrical structures. An engagement groove 282 is defined on the outer sidewall of the eleventh body 285, extending from one end to the other end of the eleventh body 285. Furthermore, two engagement grooves 282 are symmetrically defined on the outer sidewall of the eleventh body 285. A fourth groove 283 is defined on the surface of the engagement groove 282 that interfaces with the second plate 183, extending along the circumference of the engagement groove 282.

[0220] As shown in Figures 36 and 37, the outer diameter of the eleventh body 285 gradually decreases as it moves away from the eleventh end wall 284. The inner diameter of the tenth body 186 gradually increases as it moves away from the tenth end wall 185. After the second sheet 183 is connected to the coupling groove 282, the eleventh end face 2841 of the eleventh body 285 can contact the tenth end face 1851 of the tenth body 186, and the outer wall of the tenth body 186 can be flush with the outer edge of the eleventh end wall 284. As a result, after the first connector 101 and the second connector 201 are connected, the outer contour of the connecting portion 20 is roughly cylindrical. This can enhance the structural strength of the connecting portion 20, make the axial dimension of the connecting portion 20 more compact, shorten the distance between two adjacent blocking modules 10, and improve the blocking effect.

[0221] In the above embodiments, various embodiments are provided in which the first connector 101 and the second connector 201 are directly connected. As another embodiment, the first connector 101 and the second connector 201 can also be indirectly connected. Specifically, the connection portion further includes a third connector (not shown in the figure), and the first connector 101 and the second connector 201 are connected via the third connector, thereby achieving a connection between the two blocking modules.

[0222] As a specific implementation, the third connecting member is a sleeve, which can be easily operated and improve the convenience of use.

[0223] Specifically, the ends of the sleeve are connected to the first connector and the second connector, respectively. The connection between the sleeve and the first connector can adopt any of the methods described in Examples 1 to 4 above, and the connection between the sleeve and the second connector can also adopt any of the methods described in Examples 1 to 4 above. This connection method can increase the axial length of the connection portion to accommodate longer anatomical defects. In other embodiments, the first connector and the second connector can be connected together first, and the sleeve can be placed outside the first connector and / or the second connector. This can make the connection more stable and increase the outer diameter and surface smoothness of the connection portion.

[0224] Although specific embodiments of the present invention have been described above, those skilled in the art will appreciate that these are merely illustrative and that the scope of the present invention is defined by the appended claims. Those skilled in the art may make various changes or modifications to these embodiments without departing from the principles and essence of the present invention, and such changes and modifications are intended to fall within the scope of the present invention.

Claims

1. A combined blocking device, characterized in that: The blocking device comprises at least two blocking modules and corresponding connecting parts; at least two blocking modules are arranged in sequence and spaced apart, and the connecting part is provided between two adjacent blocking modules; The connecting portion includes at least two connecting members, wherein the at least two connecting members include a first connecting member and a second connecting member, and the first connecting member and the second connecting member are respectively connected to the adjacent blocking modules.

2. The combined blocking device according to claim 1, characterized in that: The blocking module comprises one of a disc-shaped structure, a cylindrical structure and a truncated cone-shaped structure; And / or, the end surface of the blocking module is a plane or a curved surface, wherein the curved surface is a curved surface convex outward along the axial direction of the blocking module, or is a curved surface concave inward along the axial direction of the blocking module.

3. The combined blocking device according to claim 2, characterized in that: The blocking modules in the blocking device are all disc-shaped structures; Or, at least one of the blocking modules in the blocking device is a cylindrical structure, and the rest are disc-shaped structures; Alternatively, at least one of the blocking modules in the blocking device is a truncated cone structure, and the rest are disc structures.

4. The combined blocking device according to any one of claims 1 to 3, characterized in that: The outer diameter of the connecting portion is smaller than the outer diameter of the blocking module; And / or, the diameters of the blocking modules of the blocking device are all different; And / or, the diameters of the blocking modules of the blocking device are all the same; And / or, the diameters of the blocking modules of the blocking device are partially the same and others are different.

5. The combined blocking device according to any one of claims 1 to 4, characterized in that: The end surface of the blocking device connected to the conveying device is a flat disk surface, or is provided with a connecting piece; And / or, the axial length of the occlusion device is configured to adapt to the defect of the anatomical structure to be occluded.

6. The combined blocking device according to any one of claims 1 to 5, characterized in that: The connection part is connected by means of chiming, mortise and tenon joints or latches.

7. The combined blocking device according to any one of claims 1 to 6, characterized in that: The occluding device is used to treat defects in various anatomical structures of patients. Preferably, the occluding device is used for structural heart disease, respiratory system, peripheral blood vessels, fistulas or cavities without blood passing through.

8. The combined blocking device according to any one of claims 1 to 7, characterized in that: The first connecting member is provided with a telescopic portion, and the second connecting member is provided with a first limiting portion; The second connecting member moves along the axial direction of the first connecting member and compresses the telescopic portion along the radial direction of the first connecting member until the telescopic portion recovers and extends into the first limiting portion, so that the second connecting member is connected to the first connecting member; Preferably, the second connecting member is sleeved on the outer side of the first connecting member, and the first limiting portion is a first groove recessed from the inner side wall of the second connecting member; The first connecting member is provided with a first accommodating cavity, and the telescopic part is arranged in the first accommodating cavity; the telescopic part includes a protruding member passing through the side wall of the first accommodating cavity, the protruding member being retracted and contracted along the radial direction of the first connecting member, and the protruding member being extended and connected to the first groove; Or, a second accommodating cavity is provided in the first connecting member, the second connecting member extends into the second accommodating cavity, and the first limiting portion is a second groove recessed from the outer side wall of the second connecting member; The telescopic portion is located in the second accommodating cavity and connected to the inner wall of the second accommodating cavity, and the telescopic portion includes a protruding portion protruding toward the inside of the second accommodating cavity, and the protruding portion abuts against the second groove; Or, the first connecting member is provided with a plug-in portion, the second connecting member is provided with a fourth accommodating cavity, the first connecting member moves along the axial direction of the second connecting member, and the plug-in portion extends into the fourth accommodating cavity until the plug-in portion moves to a predetermined position and is restricted, so that the second connecting member is connected to the first connecting member; Alternatively, the first connecting member is provided with a first engaging portion, the second connecting member is provided with a second engaging portion, and the first connecting member moves along the axial direction of the second connecting member until the first engaging portion is connected to the second engaging portion and restricts each other, so that the second connecting member is connected to the first connecting member.

9. The combined blocking device according to any one of claims 1 to 7, characterized in that: The first connecting member has a locking portion, and the second connecting member has a second limiting portion; The second connecting member rotates around the axis of the first connecting member, and the locking portion moves in the second limiting portion until being locked in the second limiting portion, so that the second connecting member is connected to the first connecting member; Preferably, the locking portion is a protrusion radially protruding from the first connecting member; The second limiting portion comprises a guide section, a transition section and a limiting section which are connected in sequence, the guide section extends from an end of the second connecting member along the axial direction of the second connecting member, the transition section extends along the circumferential direction of the second connecting member, and the limiting section extends along the axial direction of the second connecting member and is opposite to the axial extension direction of the guide section; And / or, the second limiting portion is a limiting hole, and the limiting hole passes through the side wall of the second connecting member; Preferably, an abutment portion is further provided in the second connecting member, and the abutment portion is retracted along the axial direction of the first connecting member and abuts against the end surface of the first connecting member facing the second connecting member; Alternatively, the locking portion and the second limiting portion are an internal thread and an external thread respectively, one of the internal thread and the external thread is provided on the first connecting member, and the other is provided on the second connecting member.

10. The combined blocking device according to any one of claims 1 to 7, characterized in that: The connecting portion further includes a third connecting member, through which the first connecting member and the second connecting member are connected, or after the first connecting member and the second connecting member are connected, the third connecting member is sleeved on the outside of the first connecting member and / or the second connecting member; Preferably, the third connecting member is a sleeve.

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