Injection jig
The injection jig addresses the challenge of injecting liquids into microchips with multiple ports by using positioning and guide units to align and guide the injection device, achieving safe, accurate, and cost-effective liquid injection.
Patent Information
- Application Number
- PCT/JP2024/041650
- Authority / Receiving Office
- WO · WO
- Patent Type
- Applications
- Current Assignee / Owner
- Priority Date
- 2023-12-15
- Filing Date
- 2024-11-25
- Publication Date
- 2025-06-19
AI Technical Summary
Existing technologies lack a cost-effective and safe method for injecting a liquid into a microchip with multiple injection ports, often requiring complex and expensive mechanical structures to prevent errors in puncture position and order.
An injection jig with first and second positioning units aligns an injection device with specific injection ports on a microchip, and a guide unit defines the path of the injection device between ports, ensuring correct alignment and order without the need for complex mechanisms.
The injection jig enables easy, safe, and accurate injection of liquids into microchips with multiple ports at a low cost, preventing needlestick accidents and ensuring correct puncture order.
Smart Images

Figure JP2024041650_19062025_PF_FP_ABST
Abstract
Description
Injection jig
[0001] The present technology particularly relates to an injection jig suitable for use when injecting liquid into a microchip having a plurality of injection ports.
[0002] 2. Description of the Related Art Conventionally, an injection device for injecting a biological sample into a microchip using a syringe needle has been proposed (see, for example, Patent Document 1).
[0003] International Publication No. 2022 / 224517
[0004] However, Patent Document 1 does not consider injecting liquid into a microchip having multiple injection ports.
[0005] The present technology has been made in view of such circumstances, and makes it possible to easily inject liquid into a microchip having a plurality of injection ports.
[0006] An injection jig according to one aspect of the present technology includes a first positioning unit that aligns a position of an injection tool that injects a liquid into a microchip using an injection needle to a first position that corresponds to a first injection port of the microchip, and a second positioning unit that aligns a position of the injection tool to a second position that corresponds to a second injection port of the microchip.
[0007] In one aspect of the present technology, the position of an injection device that injects a liquid into a microchip using an injection needle is adjusted to a first position corresponding to a first injection port of the microchip or a second position corresponding to a second injection port of the microchip.
[0008] 14 is a diagram showing an example of a procedure for testing a sample. FIG. 15 is an external view showing an example of the configuration of an injection device. FIG. 16 is an enlarged view of a portion of the injection device of FIG. 2. FIG. 17 is a diagram for explaining the movement of the injection device of FIG. 2. FIG. 18 is an external view showing an example of the configuration of an injection bottle. FIG. 19 is an external view showing an example of the configuration of a needle nozzle. FIG. 29 is a diagram for explaining the action of the needle nozzle. FIG. 19 is an external view showing an example of the configuration of a test chip. FIG. 20 is a diagram showing an example of the configuration of a cover of an injection jig. FIG. 21 is a diagram showing an example of the configuration of a cover of an injection jig. FIG. 22 is a cross-sectional view showing an example of the configuration of a cover of an injection jig. FIG. 23 is a diagram for explaining the movement of the injection device in the injection jig cover of FIG. 9 and FIG. 10. FIG. 24 is a diagram showing an example of the configuration of a cover of an injection jig. FIG. 25 is a diagram for explaining the movement of the injection device in the injection jig cover of FIG. 14. FIG. 26 is a diagram showing a modified example of a guide portion of the cover of the injection jig. FIG. 27 is a diagram showing a modified example of a lid portion of the cover of the injection jig. FIG. 28 is an external view showing an example of the configuration of an injection device. FIG. 29 is a diagram for explaining the movement of the injection device of FIG. 18. FIG. 29 is a diagram showing an example of the configuration of an injection device and a cover of an injection jig. FIG. 29 is a diagram showing an example of the configuration of an injection device and a cover of an injection jig. FIG. 1 is a diagram illustrating an example of the configuration of a cover for an injection jig. FIG. 2 is a cross-sectional view illustrating an example of the configuration of a cover for an injection jig. FIG. 3 is an external view illustrating an example of the configuration of an injection jig. FIG. 4 is a diagram illustrating an example of the configuration of an injection instrument and a cover for an injection jig. FIG. 5 is a diagram illustrating an example of the configuration of an injection instrument. FIG. 6 is a diagram illustrating an example of the configuration of a cover for an injection instrument and an injection jig. FIG. 7 is a diagram illustrating a method of marking a puncture position. FIG. 8 is a diagram illustrating a method of marking a puncture position. FIG. 9 is a diagram illustrating a method of injecting a suspension without using an injection bottle. FIG. 10 is a diagram illustrating a method of injecting a suspension without using an injection bottle. FIG. 11 is a diagram illustrating a method of injecting a suspension without using an injection bottle.
[0009] Hereinafter, embodiments of the present technology will be described. The description will be made in the following order: 1. Background of the present technology 2. First embodiment 3. Second embodiment 4. Modification 5. Other
[0010] <<1. Background of the Present Technology>> First, the background of the present technology will be described with reference to FIG.
[0011] FIG. 1 shows an example of a procedure for testing a sample such as human saliva.
[0012] First, a sample such as human saliva is collected.
[0013] Next, the collected specimen is suspended in a reagent, for example, in a specimen tube. Hereinafter, the reagent in which the specimen is suspended will be referred to as a suspension.
[0014] Next, a pre-processing step of filtering is performed, and the suspension is transferred from the sample tube to an injection bottle.
[0015] Next, the suspension is injected from the injection bottle into a testing microchip (hereinafter referred to as a testing chip) using an injection tool such as an injection needle.
[0016] Next, the test chip into which the suspension has been injected is attached to a testing device, and the sample is tested.
[0017] The final test results are then confirmed.
[0018] If injection needles are reused, they can cause contamination of the specimen and the equipment, making accurate testing impossible. For this reason, injection needles are generally disposable and inexpensive.
[0019] In addition, injection needles are generally fitted with a cap that acts as a cover, but the cap is removed before use, exposing the injection needle. When the injection needle is exposed, there is a risk of needlestick injuries and infection risk to the user during sample testing. There is also a risk of the needle tip being damaged during operation. Furthermore, if an operation is interrupted with the injection needle cap removed, it becomes difficult to determine whether the injection needle is unused or used, which can lead to misuse.
[0020] In response to this, an inexpensive protective cover is desired to prevent needlestick injuries, protect the injection needle, and easily determine whether the injection needle has been used.
[0021] Furthermore, when the test chip has a plurality of injection ports and injection needles must be inserted into each injection port in a predetermined order, there is a risk of human error or other errors in the puncturing position or order.
[0022] To address this issue, conventionally, for example, expensive mechanical structures or robots have been introduced to prevent mistakes in the puncture position or puncture order. Even when manual work is performed, complex mechanisms combining multiple parts have been used to prevent mistakes in the puncture position or puncture order. This has resulted in increased costs.
[0023] In response to this, there is a demand for an inexpensive mechanism that allows a person to work without making mistakes in the puncturing position or puncturing order.
[0024] Furthermore, when an injection needle is attached to a bottle into which the suspension is to be injected, the bottle is sealed. Therefore, if the injection needle is thin, the flow resistance at the needle tip increases, and the air bubbles remaining at the needle tip are not replaced by the liquid, which can result in air bubbles at the needle tip being mixed in during the injection operation, which can cause serious problems during the puncture operation.
[0025] To address this issue, it is possible to push the bottle before injection, for example, to push the air bubbles from the needle tip out with the suspension in the bottle, and remove them from the needle tip. However, this requires discarding the suspension, and the discarded liquid can cause contamination or pose a risk of exposure to infectious waste. Working while taking these points into consideration can be time-consuming and labor-intensive.
[0026] In contrast, the present technology enables a person to safely and correctly inject a liquid such as a suspension into a test chip equipped with multiple injection ports at low cost.
[0027] <<2. First Embodiment>> Next, with reference to FIGS. 2 to 10, a configuration example of an injection unit according to a first embodiment of the present technology will be described. FIG.
[0028] The injection unit is a unit used to inject the suspension to be inspected into the inspection chip 104 (see FIG. 8, etc.), which is a microchip used to inspect the suspension.
[0029] The injection unit includes an injection tool 101 (see, for example, FIG. 2), an injection bottle 102 (see, for example, FIG. 5), and an injection jig 103 (see, for example, FIG. 9).
[0030] <Configuration Example of Injection Device 101> First, a configuration example of the injection device 101 will be described with reference to Figs. 2 to 4 .
[0031] The injection device 101 includes an injection tip 111 and a protective cover 112 .
[0032] Fig. 2A shows an example of the external configuration of the injection tip 111. Fig. 2B shows an example of the external configuration of the protective cover 112. Fig. 2C shows an example of the external configuration of the injection device 101 in a state in which the injection tip 111 and the protective cover 112 are combined. Fig. 3 is a view of a part of the injection device 101 seen from a different direction than Fig. 2C.
[0033] The injection tip 111 includes an injection needle 121 and a case 122 .
[0034] The injection needle 121 is attached to the tip of the case 122 .
[0035] The tip of the case 122 is conical and has a ribbed periphery for added strength. The suspension is injected into the cylindrical portion of the case 122, where it is stored. A circular injection port is formed at the rear end of the case 122, and a flange is formed around the injection port. As will be described later, the needle nozzle 202 of the injection bottle 102 is inserted into the opening at the rear end of the case 122, and the suspension is injected from the injection bottle 102. The rear end of the cylindrical portion of the case 122 (the portion adjacent to the flange) is slightly thicker than the other portions.
[0036] The protective cover 112 includes a holding portion 151, a protective portion 152, a leaf spring 153-1, and a leaf spring 153-2.
[0037] A cylindrical insertion portion 151A is formed at the top of the holding portion 151.
[0038] Positioning keys 151B-1 and 151B-2, which are vertically long rectangular parallelepipeds, are formed at opposing positions (positions 180 degrees apart) on the side of insertion section 151A. As will be described later, positioning keys 151B-1 and 151B-2 are used to position injection device 101.
[0039] Below the positioning key 151B-1, a long, thin plate-like rib 151C-1 extends from the lower end of the insertion portion 151A. A protruding operation key 151D-1 is formed at the tip of the rib 151C-1 and protrudes in the same direction as the positioning key 151B-1.
[0040] Below the positioning key 151B-2, a long, thin plate-like rib 151C-2 extends from the lower end of the insertion portion 151A. A protruding operation key 151D-2 is formed at the tip of the rib 151C-2 and protrudes in the same direction as the positioning key 151B-2.
[0041] The protective part 152 is disposed below the holding part 151 (in the direction in which the injection needle 121 extends) and has the shape of a cylinder with a flange formed at the bottom end, with a portion cut out. By cutting out a portion of the cylinder, covers 152A-1 and 152A-2 are formed, each of which has the shape of a partially cut-out cylinder.
[0042] Rib 151C-1 of holding portion 151 is disposed above one of the gaps between covers 152A-1 and 152A-2, and rib 151C-2 is disposed above the other of the gaps between covers 152A-1 and 152A-2. One end of the tip of rib 151C-1 is connected to one end of the upper end of cover 152A-1, and the other end of the tip of rib 151C-1 is connected to one end of the upper end of cover 152A-2. One end of the tip of rib 151C-2 is connected to the other end of the upper end of cover 152A-1, and the other end of the tip of rib 151C-2 is connected to the other end of the upper end of cover 152A-2.
[0043] The lower end of the insertion portion 151A and the upper end of the protection portion 152 are connected via a leaf spring 153-1 near the rib 151C-1, and the lower end of the insertion portion 151A and the upper end of the protection portion 152 are connected via a leaf spring 153-2 near the rib 151C-2.
[0044] Injection tip 111 is inserted from above into insertion portion 151A of protective cover 112. A flange at the rear end of case 122 of injection tip 111 is supported by the upper end of insertion portion 151A, and the rear end of the outer periphery of the cylindrical portion of case 122 comes into contact with the upper end of the inner periphery of insertion portion 151A, thereby fixing injection tip 111 to protective cover 112.
[0045] When the holding part 151 and the protective part 152 are connected via the ribs 151C-1 and 151C-2, the tip of the infusion needle 121 is protected. That is, the tip of the infusion needle 121 does not protrude from the tip of the protective cover 112, and most of the periphery of the tip of the infusion needle 121 is covered (surrounded) by the covers 152A-1 and 152A-2.
[0046] Hereinafter, when there is no need to distinguish between the positioning keys 151B-1 and 151B-2, they will simply be referred to as positioning keys 151B. Hereinafter, when there is no need to distinguish between the ribs 151C-1 and 151C-2, they will simply be referred to as ribs 151C. Hereinafter, when there is no need to distinguish between the operation keys 151D-1 and 151D-2, they will simply be referred to as operation keys 151D. Hereinafter, when there is no need to distinguish between the covers 152A-1 and 152A-2, they will simply be referred to as covers 152A. Hereinafter, when there is no need to distinguish between the leaf springs 153-1 and 153-2, they will simply be referred to as leaf springs 153.
[0047] FIG. 4 shows a method for exposing the injection needle 121 to the outside of the protective cover 112 .
[0048] FIG. 4A schematically shows the injection tip 111 and the protective cover 112 combined together.
[0049] In this state, the rib 151C has the strength and rigidity to withstand being broken by lightly pressing the injection tip 111 with a finger. In other words, the rib 151C serves as a fixing mechanism that fixes the vertical position of the holding part 151 relative to the protective part 152. Therefore, even if the injection tip 111 is lightly pressed with a finger, the injection needle 121 does not become exposed from the protective cover 112, preventing needlestick injuries.
[0050] 4B, when the injection tip 111 (or the protective cover 112) is pressed downward with a force equal to or greater than a predetermined value (e.g., 400 g), the rib 151C is destroyed. More precisely, the connection between the rib 151C and the cover 152A is destroyed.
[0051] This allows the rib 151C to move into the gap between the covers 152A, making the protective cover 112 elastic. That is, the fixed position of the holding part 151 in the vertical direction is released, and the holding part 151 becomes movable in the vertical direction (the direction in which the infusion needle 121 extends) relative to the protective part 152 via the leaf springs 153-1 and 153-2. When the holding part 151 moves downward (toward the protective part 152), the tip of the infusion needle 121 becomes exposed from the lower end of the protective cover 112 (the protective part 152) as shown in Fig. 4C.
[0052] On the other hand, when the user releases the injection tip 111 and the force moving the holding portion 151 downward is released, the elasticity of the leaf springs 153-1 and 153-2 causes the injection tip 111 and the holding portion 151 to move upward (away from the protective portion 152).
[0053] As a result, the tip of the injection needle 121 returns to the inside of the protective cover 112 (protective portion 152 thereof) and is covered by the cover 152A-1 and the cover 152A-2.
[0054] In this way, by breaking the rib 151C, it becomes possible to expose the infusion needle 121 to the outside of the protective cover 112. On the other hand, even after the rib 151C is broken, the infusion needle 121 naturally returns to the inside of the protective cover 112 due to the leaf spring 153, preventing needlestick injuries.
[0055] Furthermore, even if rib 151C is broken, fragments will not fly off and protective cover 112 will maintain its shape as an integrated part, allowing the user to operate the device stably. Also, the entire protective cover 112 can be disposed of at once.
[0056] Furthermore, the destruction of the rib 151C and the irreversible deformation of the protective cover 112 allow the user to easily visually check whether the infusion needle 121 has been used or not, thereby preventing, for example, the misuse of a used infusion needle 121.
[0057] Furthermore, the protective cover 112 has a shape that can be easily molded by general two-plate or three-plate resin molding, and therefore can be produced at low cost.
[0058] <Configuration Example of Injection Bottle 102> Next, a configuration example of the injection bottle 102 will be described with reference to FIGS. 5 to 7. FIG.
[0059] The injection bottle 102 is used, for example, to inject a suspension into the injection tip 111. The injection bottle 102 includes a bottle 201 and a needle nozzle 202.
[0060] 5A and 5B show an example of the external configuration of the injection bottle 102. Fig. 6A shows an example of the external configuration of the needle nozzle 202. Fig. 6B is a view of the needle nozzle 202 as seen from the bottle 201 side. Fig. 6C schematically shows a cross section of the needle nozzle 202.
[0061] The needle nozzle 202 includes a screw cap 202A, an outer nozzle 202B, and an inner nozzle 202C.
[0062] The external nozzle 202B is formed on the outside of the cap 202A (the side opposite to the bottle 201) and is exposed to the outside of the bottle 201 when the needle nozzle 202 is attached to the bottle 201.
[0063] The internal nozzle 202C is formed inside the cap 202A (inside the bottle 201) and is housed inside the bottle 201 when the needle nozzle 202 is attached to the bottle 201.
[0064] The outer nozzle 202B has two holes, 202D and 202E. The hole 202D passes through from the tip of the outer nozzle 202B to the inside of the cap 202A. The hole 202E passes through from the tip of the outer nozzle 202B to the end of the inner nozzle 202C.
[0065] As shown schematically in FIG. 7A, the tip of the external nozzle 202B can be inserted into the injection port of the case 122 of the injection tip 111.
[0066] 7B, the suspension in bottle 201 is discharged from bottle 201 through hole 202D to the outside and injected into injection tip 111. In contrast, air in injection tip 111 is discharged from hole 202E to the top of bottle 201 (the bottom of bottle 201).
[0067] This eliminates the accumulation of air bubbles that occurs when the bottle is sealed. That is, the air that accumulates at the tip of the injection needle 121 of the injection tip 111 is removed, and the suspension in the bottle 201 can flow more easily into the injection tip 111.
[0068] <Configuration Example of Test Chip 104> FIG. 8 shows a configuration example of the test chip 104. As shown in FIG.
[0069] 8 is the front-rear direction of the test chip 104, and the horizontal direction of FIG. 8 is the left-right direction of the test chip 104. In the following description, the vertical direction of FIG.
[0070] The test chip 104 is substantially rectangular with the front right corner cut off. An injection port 104A is formed near the front left corner of the test chip 104, and an injection port 104B is formed near the center of the front edge.
[0071] The inlet 104A is a dummy inlet, into which the injection needle 121 of the injection chip 111 is punctured (inserted) and used to remove air from the tip of the injection needle 121. The inlet 104B is punctured (inserted) into which the injection needle 121 of the injection chip 111 is punctured (inserted) and used to inject the suspension in the injection bottle 102 into the test chip 104.
[0072] Near the center of the test chip 104, a substantially rectangular well 104C is formed to store the suspension injected from the injection port 104B.
[0073] <Configuration Example of Injection Jig 103> Next, a configuration example of the injection jig 103 will be described with reference to FIGS. 9 and 10. FIG.
[0074] The injection jig 103 is used to inject a suspension into the test chip 104 using the injection tip 111 of the injection instrument 101 and the injection bottle 102 with the protective cover 112 removed. The injection jig 103 includes a base 301 and a cover 302.
[0075] A of Fig. 9 is a plan view of the cover 302. B of Fig. 9 is a cross-sectional view of the cover 302. A of Fig. 10 shows a state in which the test chip 104 is placed on the base 301. B of Fig. 10 shows a state in which the cover 302 is placed on the base 301 and the injection jig 103 is assembled. C of Fig. 10 shows a state in which the injection chip 111 and the injection bottle 102 are inserted into the injection jig 103 of B of Fig. 10, and the suspension is injected into the test chip 104.
[0076] 9A will be referred to as the front-to-rear direction of injection jig 103, and the horizontal direction of A in Fig. 9A will be referred to as the left-to-right direction of injection jig 103. This also applies to the following modified examples of injection jig 103.
[0077] 10A and 10B, the base 301 is used to mount the test chip 104 and the cover 302. The base 301 includes a mounting portion 301A, a protruding portion 301B, and a protruding portion 301C.
[0078] The mounting portion 301A is a substantially rectangular plate with the front right corner and the centers of the left and right sides cut off. The test chip 104 is placed on the upper surface (hereinafter referred to as the mounting surface) of the mounting portion 301A.
[0079] U-shaped protrusions 301B and 301C are formed on the installation surface of the installation portion 301A.
[0080] The insides of the protrusions 301B and 301C are shaped to fit the outer periphery of the test chip 104. The test chip 104 is fitted into the insides of the protrusions 301B and 301C, thereby fixing the position of the test chip 104.
[0081] The protrusions 301B and the outer side of the protrusions 301B are shaped to fit the inner periphery of the lower end of the cover 302, and the base 301 and the cover 302 have a spigot-joint structure. The position of the cover 302 is fixed by fitting the lid-shaped cover 302 into the protrusions 301B and 301C of the base 301. As a result, the cover 302 covers the surface of the test chip 104, and the position of the cover 302 relative to the test chip 104 is fixed.
[0082] The cover 302 includes an opening 302A, a positioning portion 302B, a positioning portion 302C, and an opening 302D.
[0083] The opening 302A is a groove having a horizontally long opening surface and a rectangular shape with rounded corners.
[0084] The positioning portions 302B and 302C are formed below the opening 302A (at the back of the opening 302A when viewed from above the cover 302) and aligned horizontally. The positioning portions 302B and 302C each have a groove shaped to correspond to the tip of the injection tip 111.
[0085] The positioning part 302B is formed at a position corresponding to the injection port 104A of the test chip 104, i.e., at a position (hereinafter referred to as the first injection position) located above the injection port 104A, when the test chip 104 and the cover 302 are installed on the base 301. By inserting the tip of the injection chip 111 into the positioning part 302B, the injection needle 121 is fixed in a state where it is punctured into the injection port 104A of the test chip 104.
[0086] The positioning part 302C is formed at a position corresponding to the injection port 104B of the test chip 104, i.e., at a position (hereinafter referred to as the second injection position) located above the injection port 104B, when the test chip 104 and the cover 302 are installed on the base 301. By inserting the tip of the injection chip 111 into the positioning part 302C, the injection needle 121 is fixed in a state where it is punctured into the injection port 104B of the test chip 104.
[0087] For example, the user can move the injection tip 111 between the positioning portion 302B and the positioning portion 302C within the opening 302A without exposing the injection needle 121 above the cover 302.
[0088] This prevents needle stick injuries.
[0089] The opening 302D is substantially rectangular and penetrates the cover 302 in the vertical direction. The opening 302D is formed at a position corresponding to the well 104C of the test chip 104 (a position located above the well 104C) when the test chip 104 and the cover 302 are installed on the base 301.
[0090] For example, the user can check whether the well 104C of the test chip 104 is filled with suspension or not through the opening 302D.
[0091] <First Modified Example of Cover of Injection Jig 103> Next, a configuration example of a cover 351 which is a first modified example of the cover of the injection jig 103 will be described with reference to FIGS. 11 to 13 .
[0092] Fig. 11A is a perspective view of the cover 351. Fig. 11B is an enlarged view of the vicinity of the protrusion 362 of the cover 351. Fig. 12 is a cross-sectional view of the cover 351.
[0093] The cover 351 includes a lid portion 361 and a protrusion portion 362 .
[0094] The lid portion 361 is a lid-shaped member that matches the shape of the base 301 described above with reference to FIG. 10 and the like.
[0095] The protrusion 362 is formed at a position corresponding to the injection port 104A and injection port 104B of the inspection chip 104 (a position located above the injection port 104A and injection port 104B) when the inspection chip 104 and cover 351 are installed on the base 301.
[0096] An opening 351A is formed in the lid portion 361 and the protrusion portion 362. On the inner surface of the opening 351A, positioning portions 351B-1 and 351B-2, positioning portions 351C-1 and 351C-2, guide portions 351D-1 and 351D-2, guide portions 351E-1 and 351E-2, and guide portions 351F-1 and 351F-2 are formed.
[0097] Positioning portion 351B-1 corresponds to positioning key 151B of protective cover 112, and is a groove used to align injection device 101. Positioning portion 351B-1 is formed at the upper end of the inner surface in front of opening 351A when in the first injection position.
[0098] Positioning portion 351C-1 corresponds to positioning key 151B of protective cover 112 and is a groove used to align injection device 101. Positioning portion 351C-1 is formed at the upper end of the inner surface in front of opening 351A when in the second injection position.
[0099] The guide portion 351D-1 corresponds to the operation key 151D of the protective cover 112 and is a groove that defines the path of the operation key 151D. The guide portion 351D-1 is formed on the inner surface at the front of the opening 351A so as to extend in the vertical direction from the lower end of the positioning portion 351B-1. The upper end of the guide portion 351D-1 is connected to the lower end of the positioning portion 351B-1. The guide portion 351D-1 guides the injection device 101 in a direction that moves the injection needle 121 closer to or farther away from the injection port 104A of the test chip 104.
[0100] Guide portion 351E-1 corresponds to operation key 151D of protective cover 112 and is a groove that defines the path of operation key 151D. Guide portion 351E-1 extends horizontally (left and right) on the inner front surface of opening 351A and connects the midpoint of guide portion 351D-1 to the upper end of guide portion 351F-1. Guide portion 351E-1 guides injection device 101 so that it moves between the first injection position and the second injection position.
[0101] The guide portion 351F-1 corresponds to the operation key 151D of the protective cover 112 and is a groove that defines the path of the operation key 151D. The guide portion 351F-1 is formed on the inner surface in front of the opening 351A and below the positioning portion 351C-1 so as to extend in the vertical direction. The upper end of the guide portion 351F-1 is not connected to the lower end of the positioning portion 351C-1, and a gap is provided between them. The guide portion 351F-1 guides the injection device 101 in a direction that moves the injection needle 121 closer to or farther away from the injection port 104B of the test chip 104.
[0102] Positioning portion 351B-2, positioning portion 351C-2, and guide portions 351D-2 to 351F-2 are paired with positioning portion 351B-1, positioning portion 351C-1, and guide portions 351D-1 to 351F-1, respectively. Positioning portion 351B-2, positioning portion 351C-2, and guide portions 351D-2 to 351F-2 are formed on the inner surface at the rear of opening 351A at positions facing positioning portion 351B-1, positioning portion 351C-1, and guide portions 351D-1 to 351F-1, respectively.
[0103] Although not shown, the lid portion 361 may have an opening similar to the opening 302D of the cover 302 formed therein.
[0104] Hereinafter, when there is no need to distinguish between the positioning portions 351B-1 and 351B-2, they will simply be referred to as positioning portions 351B. Hereinafter, when there is no need to distinguish between the positioning portions 351C-1 and 351C-2, they will simply be referred to as positioning portions 351C. Hereinafter, when there is no need to distinguish between the guide portions 351D-1 to 351D-2, they will simply be referred to as guide portions 351D. Hereinafter, when there is no need to distinguish between the guide portions 351E-1 to 351E-2, they will simply be referred to as guide portions 351E. Hereinafter, when there is no need to distinguish between the guide portions 351F-1 to 351F-2, they will simply be referred to as guide portions 351F.
[0105] Next, the movement of the injection tool 101 in the cover 351 will be described with reference to FIG. 13 as needed.
[0106] 13A to 13D show a schematic diagram of the relationship between the operation key 151D-2 of the injection device 101 and the guide sections 351D-2 to 351F-2.
[0107] First, at the first injection position, the injection device 101 is inserted into the opening 351A so that the positioning keys 151B-1 and 151B-2 of the protective cover 112 are inserted into the positioning portions 351B-1 and 351B-2 of the cover 351.
[0108] As a result, operation keys 151D-1 and 151D-2 of protective cover 112 are guided by guide portions 351D-1 and 351D-2 of cover 351, and injection tool 101 moves downward above injection port 104A of test chip 104.
[0109] Then, after the lower end of the protective cover 112 abuts against the upper surface of the test chip 104, when the injection instrument 101 is further pressed downward, the rib 151C of the protective cover 112 is destroyed. This allows the injection chip 111 held by the holding part 151 of the protective cover 112 to move in the vertical direction (the direction in which the injection needle 121 extends) relative to the protection part 152 of the protective cover 112. In other words, the injection needle 121 can be exposed from the lower end of the protective cover 112.
[0110] Furthermore, as shown in B of Figure 13, when injection device 101 is pressed downward, positioning keys 151B-1, 151B-2, operation keys 151D-1, and 151D-2 of protective cover 112 come into contact with the lower ends of positioning portions 351B-1, 351B-2, guide portions 351D-1, and guide portions 351D-2 of cover 351, respectively.
[0111] At this time, the injection needle 121 is inserted into the injection port 104A of the test chip 104. Then, air is released from the tip of the injection needle 121 at the injection port 104A.
[0112] Next, injection device 101 is lifted up until operation keys 151D-1 and 151D-2 of protective cover 112 reach the height of guide portions 351E-1 and 351E-2 of cover 351. Then, as shown in Fig. 15C, operation keys 151D-1 and 151D-2 of protective cover 112 are guided by guide portions 351E-1 and 351E-2 of cover 351, and injection device 101 moves from the first injection position toward the second injection position.
[0113] Then, when operation keys 151D-1 and 151D-2 of protective cover 112 reach guide portions 351F-1 and 351F-2 of cover 351, injection device 101 is placed in the second injection position.
[0114] Next, as shown in FIG. 13D, when injection device 101 is pressed downward, positioning keys 151B-1, 151B-2, operation keys 151D-1, and 151D-2 of protective cover 112 come into contact with the lower ends of positioning portions 351C-1, 351C-2, guide portions 351F-1, and guide portions 351F-2 of cover 351, respectively.
[0115] At this time, the injection needle 121 is inserted into the injection port 104B of the test chip 104. Then, the suspension in the injection bottle 102 is injected into the test chip 104 from the injection port 104B via the injection chip 111.
[0116] Then, the injection device 101 is removed from the cover 351 by reversing the procedure described above. However, since there is no need to insert the injection needle 121 into the test chip 104 at the first injection position, the injection device 101 is not pushed down but is simply pulled up.
[0117] The guide portions 351D-1 and 351D-2 are connected to the positioning portions 351B-1 and 351B-2. Therefore, the operation keys 151D-1 and 151D-2 of the protective cover 112 can be moved to the guide portions 351D-1 and 351D-2 without going through the horizontal guide portions 351E-1 and 351E-2. This allows the user to insert the injection device 101 into the opening 351A from above the positioning portions 351B-1 and 351B-2, and then insert the injection needle 121 directly into the injection port 104A of the test chip 104.
[0118] On the other hand, the guide portions 351F-1 and 351F-2 are not connected to the positioning portions 351C-1 and 351C-2. Therefore, the operation keys 151D-1 and 151D-2 of the protective cover 112 cannot be moved to the guide portions 351F-1 and 351F-2 without passing through the horizontal guide portions 351E-1 and 351E-2. Therefore, even if the user inserts the injection device 101 into the opening 351A from above the positioning portions 351C-1 and 351C-2, the user cannot insert the injection needle 121 into the injection port 104B of the test chip 104.
[0119] In other words, the user cannot insert the injection needle 121 into the injection port 104B of the test chip 104 unless he or she first inserts the operation keys 151D-1 and 151D-2 of the protective cover 112 into the guide portions 351D-1 and 351D-2, and then moves them via the guide portions 351E-1 and 351E-2 to the guide portions 351F-1 and 351F-2.
[0120] In this way, the fail-safe mechanism of the cover 351 prevents the injection needle 121 from being inserted in the wrong order. That is, the injection needle 121 is reliably inserted into the injection port 104A and then the injection port 104B of the test chip 104 in that order. Therefore, it is possible to easily, reliably, and safely insert the injection needle 121 into the injection port 104A and the injection port 104B of the test chip 104, and inject the suspension into the test chip 104.
[0121] <Second Modification of Cover of Injection Jig 103> Next, with reference to Figs. 14 and 15, a configuration example of a cover 401 that is a second modification of the cover of the injection jig 103 will be described.
[0122] The cover 401 includes a lid portion 411 and an adapter 412 .
[0123] FIG. 14 is an enlarged view of the vicinity of the adapter 412 of the cover 401.
[0124] The lid portion 411 has substantially the same shape as the lid portion 361 of the cover 351 .
[0125] An opening 411A is formed in the lid portion 411. The opening 411A is formed at approximately the same position as the opening 351A of the cover 351 formed in the lid portion 361, and has approximately the same shape.
[0126] On the inner surface of the opening 411A, guide portions 411B-1 and 411B-2, guide portions 411C-1 and 411C-2, and guide portions 411D-1 and 411D-2 are formed.
[0127] The guide portion 411B-1 is formed at a position substantially similar to the shape of the lid portion 361 of the guide portion 351D-1 of the cover 351, and has substantially the same shape.
[0128] The guide portion 411B-2 is formed at a position substantially similar to the shape of the lid portion 361 of the guide portion 351D-2 of the cover 351, and has substantially the same shape.
[0129] Guide portions 411D-1, 411D-2, 411E-1, and 411E-2 are formed in approximately the same positions as guide portions 351D-1, 351D-2, 351E-1, and 351E-2 of cover 351, and have approximately the same shapes.
[0130] The adapter 412 has a rectangular plate shape with rounded corners on the top surface thereof. An opening 412A having a rectangular opening surface is formed in the center of the adapter 412 and penetrates the adapter 412 in the vertical direction.
[0131] Positioning portions 412B-1 and 412B-2, as well as guide portions 412C-1 and 412C-2, are formed on the inner surface of the opening 412A.
[0132] The positioning portion 412B-1 is formed at the upper end and center of the inner front surface of the opening 412A, and has the same shape as the positioning portions 351B and 351C of the cover 351.
[0133] The guide portion 412C-1 is formed below the positioning portion 412B-1, and has the same shape as the portion formed on the protrusion 362 of the guide portion 351D-1 of the cover 351.
[0134] The positioning portion 412B-2 and the guide portion 412C-1 are paired with the positioning portion 412B-1 and the guide portion 412C-1, respectively. The positioning portion 412B-2 and the guide portion 412C-1 are formed on the inner surface at the rear of the opening 412A at positions facing the positioning portion 412B-1 and the guide portion 412C-1.
[0135] The adapter 412 has a sliding mechanism that can slide left and right relative to the cover portion 411 .
[0136] For example, when no force is applied, the adapter 412 is positioned at the left end in the sliding direction by a spring (not shown). In this state, the positioning portions 412B-1 and 412B-2 are positioned in the same positions as the positioning portions 351B-1 and 351B-2 of the cover 351. That is, the positioning portions 412B-1 and 412B-2 are positioned at the first injection position. Furthermore, the guide portion 412C-1 is connected to the guide portion 411B-1, and the guide portion 412C-2 is connected to the guide portion 411B-2.
[0137] For example, when the adapter 412 is positioned at the right end in the sliding direction, the positioning portions 412B-1 and 412B-2 are positioned in the same positions as the positioning portions 351C-1 and 351C-2 of the cover 351. That is, the positioning portions 412B-1 and 412B-2 are positioned at the second injection position. Furthermore, the guide portion 412C-1 is connected to the guide portion 411D-1, and the guide portion 412C-2 is connected to the guide portion 411D-2.
[0138] Hereinafter, when there is no need to distinguish between guide portion 411B-1 and guide portion 411B-2, they will simply be referred to as guide portion 411B. Hereinafter, when there is no need to distinguish between guide portion 411C-1 and guide portion 411C-2, they will simply be referred to as guide portion 411C. Hereinafter, when there is no need to distinguish between guide portion 411D-1 and guide portion 411D-2, they will simply be referred to as guide portion 411D.
[0139] Next, the movement of the injection tool 101 in the cover 401 will be described.
[0140] First, with the adapter 412 positioned at the left end, the injection device 101 is inserted into the opening 412A. At this time, for example, the injection device 101 is inserted into the opening 412A so that the positioning keys 151B-1 and 151B-2 of the protective cover 112 are inserted into the positioning portions 412B-1 and 412B-2 of the adapter 412.
[0141] As a result, operation keys 151D-1 and 151D-2 of protective cover 112 are guided by guide portions 412C-1 and 411B-1, and guide portions 412C-2 and 411B-2 of cover 401, causing injection device 101 to move downward above injection port 104A of test chip 104.
[0142] Then, after the lower end of the protective cover 112 abuts against the upper surface of the test chip 104, when the injection instrument 101 is further pressed downward, the rib 151C of the protective cover 112 is destroyed. This allows the injection chip 111 held by the holding part 151 of the protective cover 112 to move in the vertical direction (the direction in which the injection needle 121 extends) relative to the protection part 152 of the protective cover 112. In other words, the injection needle 121 can be exposed from the lower end of the protective cover 112.
[0143] Furthermore, when injection device 101 is pressed downward from above, positioning keys 151B-1, 151B-2, operation keys 151D-1, and 151D-2 of protective cover 112 come into contact with the lower ends of positioning portions 412B-1, 412B-2, guide portions 411B-1, and guide portions 411B-2 of cover 401, respectively.
[0144] At this time, the injection needle 121 is inserted into the injection port 104A of the test chip 104. Then, air is released from the tip of the injection needle 121 at the injection port 104A.
[0145] Next, injection device 101 is lifted up until operation keys 151D-1 and 151D-2 of protective cover 112 are at the same height as guide portions 411C-1 and 411C-2 of cover 401. Then, adapter 412 is slid to the right, whereby operation keys 151D-1 and 151D-2 of protective cover 112 are guided by guide portions 411C-1 and 411C-2 of cover 401, and injection device 101 moves from the first injection position toward the second injection position.
[0146] Then, when the adapter 412 is positioned at the right end and the operation keys 151D-1 and 151D-2 of the protective cover 112 reach the guide portions 411D-1 and 411D-2 of the cover 401, the injection device 101 is positioned at the second injection position.
[0147] Next, when injection device 101 is pressed downward from above, positioning keys 151B-1, 151B-2, operation keys 151D-1, and 151D-2 of protective cover 112 come into contact with the lower ends of positioning portions 412B-1, 412B-2, guide portions 411D-1, and guide portions 411D-2 of cover 401, respectively.
[0148] At this time, the injection needle 121 is inserted into the injection port 104B of the test chip 104. Then, the suspension in the injection bottle 102 is injected into the test chip 104 from the injection port 104B via the injection chip 111.
[0149] Then, the injection tool 101 is removed from the cover 401 by pulling the injection tool 101 upward.
[0150] The adapter 412 is positioned at the left end (first injection position) when no force is applied. Therefore, the operator is guided to first insert the injection needle 121 into the injection port 104A of the test chip 104 at the first injection position. This prevents the operator from inserting the needle in the wrong order.
[0151] When the cover 401 having the adapter 412, which is a slide mechanism, is used, the operation key 151D of the protective cover 112 can be eliminated.
[0152] FIG. 15 shows a schematic example of the movement of the injection device 101 in the cover 401 when the operation key 151D of the protective cover 112 is removed.
[0153] In this case, the positioning portion 412B and the guide portion 411C of the cover 401 are eliminated. Furthermore, the guide portions 411C, 411D, and 411B of the cover 401 are shaped to allow insertion of the positioning key 151B of the protective cover 112. Furthermore, a positioning portion (not shown) for the positioning key 151B of the protective cover 112 is formed in the guide portions 411B and 411D.
[0154] 15A and 15B, with the adapter 412 positioned at the left end, the positioning keys 151B-1 and 151B-2 of the protective cover 112 are guided by the guide portions 412C-1 and 411B-1, and the guide portions 412C-2 and 411B-2 of the cover 401, causing the injection device 101 to move downward to the first injection position. The positioning keys 151B-1 and 151B-2 of the protective cover 112 then come into contact with the lower ends of the positioning portions formed on the guide portions 411B-1 and 411B-2, respectively.
[0155] At this time, the injection needle 121 is inserted into the injection port 104A of the test chip 104. In this state, the adapter 412 does not slide in the left-right direction.
[0156] 15C, the injection device 101 is then pulled up until the positioning keys 151B-1 and 151B-2 of the protective cover 112 are positioned inside the adapter 412. This allows the adapter 412 to slide left and right.
[0157] Then, as shown in Fig. 15D, the adapter 412 is slid to the right and positioned at the right end as shown in Fig. 15E. As a result, the positioning keys 151B-1 and 151B-2 of the protective cover 112 are guided by the adapter 412, and the injection device 101 moves from the first injection position to the second injection position.
[0158] In this state, positioning keys 151B-1 and 151B-2 of protective cover 112 are guided by guide portions 412C-1 and 411D-1, and guide portions 412C-2 and 411D-2 of cover 401, causing injection device 101 to move downward to the second injection position. Positioning keys 151B-1 and 151B-2 of protective cover 112 then abut against the lower ends of the positioning portions formed on guide portions 411D-1 and 411D-2, respectively.
[0159] At this time, the injection needle 121 is inserted into the injection port 104B of the test chip 104. In this state, the adapter 412 does not slide in the left-right direction.
[0160] In this way, the operation key 151D of the protective cover 112 can be eliminated.
[0161] 16, for example, the guide portions 411C-1 and 411C-2 of the cover 401 may be inclined obliquely. That is, the height of the guide portions 411C-1 and 411C-2 at the first injection position may be greater than the height of the guide portions 411C-1 and 411C-2 at the second injection position. In other words, the distance between the guide portions 411C-1 and 411C-2 and the test chip 104 (the injection port 104A) at the first injection position may be greater than the distance between the guide portions 411C-1 and 411C-2 and the test chip 104 (the injection port 104B) at the second injection position.
[0162] As a result, at the first injection position, unless rib 151C of protective cover 112 is broken and protective cover 112 is made elastic, injection device 101 cannot be moved from the first injection position to the second injection position.
[0163] This prevents the injection needles 121 from being inserted in the wrong order.
[0164] This can also be applied to the guide portions 351E-1 and 351E-2 of the protective cover 112 in FIG.
[0165] Also, for example, in the case where the operation key 151D of the protective cover 112 is deleted as described above with reference to FIG. 15, the upper surface of the lid portion 411 of the cover 401 may be inclined obliquely as shown in FIG. 17.
[0166] That is, the height of the upper surface of the lid portion 411 at the first injection position may be higher than the height of the upper surface of the lid portion 411 at the second injection position. As a result, the height of the adapter 412 at the first injection position is higher than the height of the adapter 412 at the second injection position. In other words, the distance between the adapter 412 and the test chip 104 (the injection port 104A) at the first injection position is longer than the distance between the adapter 412 and the test chip 104 (the injection port 104B) at the second injection position.
[0167] As a result, at the first injection position, unless rib 151C of protective cover 112 is broken and protective cover 112 is made elastic, injection device 101 cannot be moved from the first injection position to the second injection position.
[0168] This prevents the injection needles 121 from being inserted in the wrong order.
[0169] <<3. Second Embodiment>> Next, a second embodiment of the present technology will be described with reference to FIGS. 18 to 23 .
[0170] FIG. 18 shows an example of the external configuration of an injection device 501 according to a second embodiment of the injection device.
[0171] The injection device 501 is the same as the injection device 101 in that it includes an injection tip 111 , but differs in that it includes a protective cover 511 instead of the protective cover 112 .
[0172] The protective cover 511 is significantly different from the protective cover 112 in that a coil spring 523 is used as the elastic body instead of the leaf spring 153. Specifically, the protective cover 511 includes a holding member 521, a protective member 522, and the coil spring 523.
[0173] The holding member 521 is formed with an insertion portion 521A, positioning keys 521B-1 and 521B-2, operation keys 522C-1 and 522C-2, a mounting portion 521D, and stoppers 521E-1 and 521E-2.
[0174] The insertion portion 521A has substantially the same shape as the insertion portion 151A of the holding portion 151 of the protective cover 112.
[0175] The positioning keys 521B-1 and 521B-2 are arranged in approximately the same positions in the height direction and circumferential direction as the positioning keys 151B-1 and 151B-2 of the holding portion 151 of the protective cover 112. The horizontal width of the positioning keys 521B-1 and 521B-2 is the same as that of the positioning keys 151B-1 and 151B-2. The vertical length of the positioning keys 521B-1 and 521B-2 is shorter than that of the positioning keys 151B-1 and 151B-2.
[0176] The operation key 521C-1 is connected to the positioning key 521B-1 and is located below the positioning key 521B-1, slightly lower than the mounting portion 521D. The operation key 521C-1 has a rectangular parallelepiped shape that is slightly smaller than the positioning key 521B-1, and protrudes in the same direction as the positioning key 521B-1.
[0177] The operation key 521C-2 is connected to the positioning key 521B-2 and is arranged below the positioning key 521B-2 at the same height as the operation key 521C-1. The operation key 521C-2 has the same shape as the operation key 521C-2 and protrudes in the same direction as the positioning key 521B-2.
[0178] Below the insertion portion 521A, a cylindrical mounting portion 521D is formed, which has an inner diameter equal to that of the insertion portion 521A and an outer diameter slightly smaller than that of the insertion portion 521A.
[0179] A downwardly extending stopper 521E-1 is formed below the mounting portion 521D at approximately the same circumferential position as the positioning key 521B-1. The stopper 521E-1 has the shape of a cylinder with the same inner diameter as the mounting portion 521D, with a portion cut away vertically, and has rounded corners at the bottom.
[0180] A stopper 521E-2 extending downward is formed below the mounting portion 521D at approximately the same position as the positioning key 521B-2 in the circumferential direction. The stopper 521E-2 has the same shape as the stopper 521E-1.
[0181] The protection member 522 includes a mounting portion 522A, covers 522B-1 and 522B-2, and operation keys 522C-1 and 522C-2.
[0182] The mounting portion 522A has a cylindrical shape with a flange formed at the bottom end. The inner and outer diameters of the cylindrical portion of the mounting portion 522A are approximately the same as those of the mounting portion 521D of the holding member 521.
[0183] The cover 522B-1 extends upward from the upper end of the mounting portion 522A, and is disposed at approximately the same position in the circumferential direction as the stopper 521E-1 in the state shown in Fig. 18. The cover 522B-1 has a shape similar to that of the stopper 521E-1 turned upside down.
[0184] The cover 522B-2 extends upward from the upper end of the mounting portion 522A, and is disposed at approximately the same position in the circumferential direction as the stopper 521E-2 in the state shown in Fig. 18. The cover 522B-2 has a shape similar to that of the stopper 521E-2 turned upside down.
[0185] The operation keys 522C-1 and 522C-2 protrude outward from the flange of the mounting portion 522A. The operation key 522C-1 is located midway between the covers 522B-1 and 522B-2 in the circumferential direction. The operation key 522C-2 is located opposite the operation key 522C-1 in the circumferential direction.
[0186] The upper end of the coil spring 523 is attached around the attachment portion 521D of the holding member 521, and the lower end of the coil spring 523 is attached around the attachment portion 522A of the protection member 522.
[0187] In this state, the stoppers 521E-1 and 521E-2 function as a fixing mechanism that fixes the vertical position of the holding member 521 relative to the protective member 522. Therefore, even if the injection tip 111 is lightly pressed with a finger, the injection needle 121 does not become exposed from the protective cover 511, preventing needlestick injuries.
[0188] Hereinafter, when there is no need to distinguish between the positioning keys 521B-1 and 521B-2, they will simply be referred to as the positioning keys 521B. Hereinafter, when there is no need to distinguish between the operation keys 521C-1 and 521C-2, they will simply be referred to as the operation keys 521C. Hereinafter, when there is no need to distinguish between the stoppers 521E-1 and 521E-2, they will simply be referred to as the stoppers 521E. Hereinafter, when there is no need to distinguish between the covers 522B-1 and 522B-2, they will simply be referred to as the covers 522B. Hereinafter, when there is no need to distinguish between the operation keys 522C-1 and 522C-2, they will simply be referred to as the operation keys 522C.
[0189] Next, the operation of the injection device 501 will be described with reference to FIG.
[0190] In FIG. 19C, the coil spring 523 is omitted for clarity.
[0191] 19A, when the holding member 521 is rotated approximately 90 degrees in the direction of the arrow around an axis passing through the infusion needle 121 relative to the protective member 522, the stopper 521E of the holding member 521 is positioned between the cover 522B of the protective member 522. This makes the protective cover 511 elastic. That is, the fixed position of the holding member 521 in the up-down direction is released, and the holding member 521 becomes movable in the up-down direction (the direction in which the infusion needle 121 extends) relative to the protective member 522 via the coil spring 523.
[0192] The rotation direction may be reversed.
[0193] 19C, when the injection tip 111 is pressed down, the holding member 521 moves downward together with the injection tip 111. As a result, the injection needle 121 of the injection tip 111 becomes exposed from the lower end of the protective cover 511.
[0194] On the other hand, when the user releases the injection tip 111 and the force moving the holding member 521 downward is released, the elastic force of the coil spring 523 causes the injection tip 111 and the holding member 521 to move upward (away from the protective member 522).
[0195] As a result, the tip of the infusion needle 121 returns to the inside of the protective cover 511 (protective member 522 thereof) and is covered by the cover 522B-1 and the cover 522B-2.
[0196] Also, as shown in Figure 19D, in contrast to Figure 19B, when the holding member 521 is rotated approximately 90 degrees in the direction of the arrow relative to the protective member 522 and returned to its original position, the stopper 521E of the holding member 521 abuts against the cover 522B of the protective member 522, and the position of the holding member 521 is fixed.
[0197] In this way, by rotating the holding member 521, it is possible to expose the infusion needle 121 to the outside of the protective cover 112. On the other hand, even if the holding member 521 is rotated, the infusion needle 121 naturally returns to the inside of the protective cover 112 due to the coil spring 523, thereby preventing needlestick injuries.
[0198] Furthermore, by rotating the holding member 521 in the reverse direction, the protective cover 511 returns to its original state, so that the protective cover 511 can be reused.
[0199] Next, with reference to FIGS. 20 to 23, a configuration example of a cover 551 for an injection jig corresponding to the injection device 501 will be described.
[0200] Fig. 20 is a view of the injection device 501 and the cover 551 as viewed from above. Fig. 21 is a view of the injection device 501 and the cover 551 as viewed from below. Fig. 21 is a schematic diagram of the internal configuration of the cover 551. Fig. 22 is a schematic diagram of a cross section of the cover 551.
[0201] 20 to 23, for ease of understanding, only the periphery of the portion of cover 551 where injection tool 501 is inserted is shown. In reality, an opening similar to opening 302D of cover 302 in FIG. 10 is provided.
[0202] The cover 551 is formed with an opening 551A having an opening surface that is roughly shaped like a rounded rectangle that is long in the left-right direction.
[0203] On the inner surface of opening 551A, guide portion 551B, guide portion 551C-1 and guide portion 551C-1, guide portion 551D-1 and guide portion 551D-2, guide portion 551E-1 and guide portion 551E-2, guide portion 551F-1 and guide portion 551F-2, guide portion 551G-1 and guide portion 551G-2, guide portion 551H-1 and guide portion 551H-2, guide portion 551I-1 and guide portion 551I-2, guide portion 551J-1 and guide portion 551J-2, guide portion 551K-1 and guide portion 551K-2, positioning portion 551L-1 and positioning portion 551L-2, and positioning portion 551M-1 and positioning portion 551M-2 are formed.
[0204] The guide portion 551B is a groove corresponding to the operation key 521C of the protective cover 511, and is formed at the upper end of the left inner surface of the opening 551A.
[0205] The guide portion 551C-1 is a groove corresponding to the operation key 522C of the protective cover 511, and penetrates the cover 551 in the vertical direction near the upper and left ends of the inner surface in front of the opening 551A.
[0206] The guide portion 551D-1 is a groove corresponding to the operation key 521C of the protective cover 511, extends in an arc shape in the horizontal direction, and connects the guide portion 551B and the guide portion 551E-1.
[0207] Guide portion 551E-1 is a groove corresponding to operation key 521C of protective cover 511, overlaps with a part of guide portion 551C-1, extends in the vertical direction, and connects the right end of guide portion 551D-1 and the left end of guide portion 551F-1.
[0208] Guide portion 551F-1 is a groove corresponding to operation key 521C of protective cover 511, extends in the left-right direction on the inner surface in front of opening 551A, and connects guide portion 551E-1 and guide portion 551G-1.
[0209] Guide portion 551G-1 is a groove corresponding to operation key 521C of protective cover 511, and extends vertically on the front inner surface of opening 551A from a position slightly higher than guide portion 551F-1 to halfway on the front inner surface of opening 551A.
[0210] Guide portion 551H-1 is a groove corresponding to operation key 521C of protective cover 511, extends left and right on the front inner surface of opening 551A, and connects the upper end of guide portion 551G-1 and the upper end of guide portion 551I-1.
[0211] Guide portion 551I-1 is a groove corresponding to operation key 521C of protective cover 511, and extends vertically on the front inner surface of opening 551A from the right end of guide portion 551H-1 to the same depth as guide portion 551G-1.
[0212] Guide portion 551J-1 is a passage corresponding to operation key 522C of protective cover 511, extends in the left-right direction at the lower end of the inner front surface of opening 551A, and connects the lower end of guide portion 551C-1 and guide portion 551K-1.
[0213] Guide portion 551K-1 is a passage corresponding to operation key 522C of protective cover 511, and extends in the left-right direction from near the left end of guide portion 551G-1 to near the right end of guide portion 551I-1 at the lower end of the inner surface in front of opening 551A. The vertical width of guide portion 551K-1 is longer than the vertical width of guide portion 551J-1.
[0214] The positioning portion 551L-1 is a groove corresponding to the positioning key 521B of the protective cover 511, and is formed at the upper end of the inner surface in front of the opening 551A and above the guide portion 551G-1. The positioning portion 551L-1 and the guide portion 551G-1 are not connected, and a gap is provided between them.
[0215] The positioning portion 551M-1 is a groove that corresponds to the positioning key 521B of the protective cover 511, and is formed at the upper end of the inner surface in front of the opening 551A and above the guide portion 551I-1. The positioning portion 551M-1 and the guide portion 551I-1 are not connected, and a gap is provided between them.
[0216] Guide portions 551C-2 through 551K-2, positioning portions 551L-2 and 551M-2 are paired with guide portions 551C-1 through 551K-1, positioning portions 551L-1 and 551M-1, respectively. Guide portions 551C-2 through 551K-2, positioning portions 551L-2 and 551M-2 are formed on the inner surface at the rear of opening 551A at positions facing guide portions 551C-1 through 551K-1, positioning portions 551L-1 and 551M-1, respectively.
[0217] Hereinafter, when there is no need to distinguish between guide portion 551C-1 and guide portion 551C-2, they will simply be referred to as guide portion 551C. Hereinafter, when there is no need to distinguish between guide portion 551D-1 and guide portion 551D-2, they will simply be referred to as guide portion 551D. Hereinafter, when there is no need to distinguish between guide portion 551E-1 and guide portion 551E-2, they will simply be referred to as guide portion 551E. Hereinafter, when there is no need to distinguish between guide portion 551F-1 and guide portion 551F-2, they will simply be referred to as guide portion 551F. Hereinafter, when there is no need to distinguish between guide portion 551G-1 and guide portion 551G-2, they will simply be referred to as guide portion 551G. Hereinafter, when there is no need to distinguish between guide portion 551H-1 and guide portion 551H-2, they will simply be referred to as guide portion 551H. Hereinafter, when there is no need to distinguish between guide portion 551I-1 and guide portion 551I-2, they will simply be referred to as guide portion 551I. Hereinafter, when there is no need to distinguish between guide portion 551J-1 and guide portion 551J-2, they will simply be referred to as guide portion 551J. Hereinafter, when there is no need to distinguish between guide portion 551K-1 and guide portion 551K-2, they will simply be referred to as guide portion 551K. Hereinafter, when there is no need to distinguish between positioning portion 551L-1 and positioning portion 551L-2, they will simply be referred to as positioning portion 551L. Hereinafter, when there is no need to distinguish between positioning portion 551M-1 and positioning portion 551M-2, they will simply be referred to as positioning portion 551M.
[0218] Next, the movement of the injection tool 501 in the cover 551 will be described.
[0219] First, the position of operation key 521C-1 of protective cover 511 is aligned with guide portion 551B of cover 551, and the positions of operation keys 522C-1 and 522C-2 of protective cover 511 are aligned with guide portions 551C-1 and 551C-2 of cover 551, respectively, and then injection device 501 is inserted into opening 551A.
[0220] Next, when operation key 521C-1 of protective cover 511 abuts against the lower end of guide portion 551B, holding member 521 is rotated 90 degrees counterclockwise when viewed from above. As a result, operation keys 521C-1 and 521C-2 of protective cover 511 are guided by guide portions 551D-1 and 551D-2 of cover 551, respectively, and reach guide portions 551E-1 and 551E-2.
[0221] Next, injection tool 501 is pushed downward. As a result, operation keys 521C-1 and 521C-2 of protective cover 511 are guided by guide portions 551E-1 and 551E-2 of cover 551, respectively, and reach guide portions 551F-1 and 551F-2. Also, operation keys 522C-1 and 522C-2 of protective cover 511 are guided by guide portions 551C-1 and 551C-2 of cover 551, respectively, and reach guide portions 551J-1 and 551J-2.
[0222] Next, the injection device 501 is slid to the right. As a result, operation keys 521C-1 and 521C-2 of the protective cover 511 are guided by guide portions 551F-1 and 551F-2 of the cover 551, respectively, and reach guide portions 551G-1 and 551G-2. Furthermore, operation keys 522C-1 and 522C-2 of the protective cover 511 are guided by guide portions 551J-1 and 551J-2 of the cover 551, respectively, and reach guide portions 551K-1 and 551K-2. As a result, the injection device 501 is positioned in the first injection position.
[0223] Next, injection tool 501 is pressed downward. As a result, positioning keys 521B-1 and 521B-2 of protective cover 511 are inserted into positioning portions 551L-1 and 551L-2, respectively, of cover 551. Furthermore, operation keys 521C-1 and 521C-2 of protective cover 511 are guided by guide portions 551G-1 and 551G-2, respectively, of cover 551, and reach the lower ends of guide portions 551G-1 and 551G-2.
[0224] As a result, the holding member 521 moves downward relative to the protection member 522 , and the infusion needle 121 protrudes from the lower end of the protection member 522 .
[0225] Here, the positioning portions 551L-1 and 551L-2 of the cover 551 are formed at positions corresponding to the injection port 104A of the test chip 104. Therefore, the injection needle 121 of the injection tool 501 is inserted into the injection port 104A of the test chip 104.
[0226] Next, injection device 501 is lifted upward until operation keys 521C-1 and 521C-2 of protective cover 511 reach the upper ends of guide portions 551G-1 and 551G-2 of cover 551. As a result, positioning keys 521B-1 and 521B-2 of protective cover 511 move out of positioning portions 551L-1 and 551L-2 of cover 551.
[0227] Next, the injection device 501 is slid to the right. As a result, operation keys 521C-1 and 521C-2 of the protective cover 511 are guided by guide portions 551H-1 and 551H-2 of the cover 551, respectively, and reach guide portions 551I-1 and 551I-2. Furthermore, operation keys 522C-1 and 522C-2 of the protective cover 511 are guided by guide portions 551K-1 and 551K-2 of the cover 551, respectively, and reach the right ends of guide portions 551K-1 and 551K-2. As a result, the injection device 501 is positioned in the second injection position.
[0228] Next, injection tool 501 is pressed downward. As a result, positioning keys 521B-1 and 521B-2 of protective cover 511 are inserted into positioning portions 551M-1 and 551M-2, respectively, of cover 551. Furthermore, operation keys 521C-1 and 521C-2 of protective cover 511 are guided by guide portions 551I-1 and 551I-2, respectively, of cover 551, and reach the lower ends of guide portions 551I-1 and 551I-2.
[0229] As a result, the holding member 521 moves downward relative to the protection member 522 , and the infusion needle 121 protrudes from the lower end of the protection member 522 .
[0230] Here, the positioning portions 551M-1 and 551M-2 of the cover 551 are formed at positions corresponding to the injection port 104B of the test chip 104. Therefore, the injection needle 121 of the injection tool 501 is inserted into the injection port 104B of the test chip 104.
[0231] The injection device 501 is removed from the cover 551 by reversing the procedure described above. However, since it is not necessary to insert the injection needle 121 into the injection port 104A of the test chip 104, the operation keys 521C-1 and 521C-2 of the protective cover 511 are lowered in the guide portions 551G-1 and 551G-2 to the height of the guide portions 551J-1 and 551J-2, and then slid leftward along the guide portions 551J-1 and 551J-2.
[0232] In this way, the user is prevented from making a mistake in the order of puncturing with the injection needle 121. That is, the injection needle 121 is reliably inserted into the injection port 104A and then the injection port 104B of the test chip 104 in this order.
[0233] <Modification of Injection Device 501> Next, with reference to Figs. 24 and 25, a configuration example of an injection device 601, which is a modification of the injection device 501, will be described.
[0234] Fig. 24 shows an example of the external configuration of the injection device 601. Fig. 24A shows the injection device 601 with the cap 621 removed, and Fig. 24B shows the injection device 601 with the cap 621 attached.
[0235] The injection device 601 is the same as the injection device 501 in that it includes an injection tip 111 , but differs in that it includes a protective cover 611 instead of the protective cover 511 .
[0236] The protective cover 611 is the same as the protective cover 511 in that it includes a holding member 521 and a coil spring 523 , but differs in that it includes a cap 621 instead of the protective member 522 .
[0237] 24 and 25, the shape of the holding member 521 is shown in a partially simplified manner.
[0238] The cap 621 is placed on the tip of the injection tip 111 and covers the area including the periphery of the injection needle 121 .
[0239] FIG. 25 is a cross-sectional view showing a schematic configuration example of a cover 651 of an injection jig corresponding to the injection device 601.
[0240] A guide portion 651A consisting of a deep groove is formed at the left end of the cover 651. An insertion portion 651B is formed at the tip of the guide portion 651A.
[0241] Insertion section 651B has a smaller diameter than the other parts of guide section 651A. When injection device 601 is pushed deep into guide section 651A and the tip of cap 621 is inserted into insertion section 651B, and injection device 601 is then pulled upward, cap 621 is held by insertion section 651B, and cap 621 is removed from injection device 601.
[0242] Thereafter, in the same manner as in the injection tool 501 , the injection needle 121 is inserted into the injection port 104 A and the injection port 104 B of the test chip 104 , and the suspension is injected into the test chip 104 .
[0243] Before the injection device 601 is removed from the cover 651 , the injection device 601 may be inserted all the way into the guide portion 651A, and the cap 621 may be reattached to the injection device 601 .
[0244] Even when the cap 621 is removed from the injection device 601, the coil spring 523 makes it difficult for fingers or the like to access the tip of the injection needle 121, thereby preventing needlestick injuries.
[0245] <<4. Modifications>> Modifications of the above-described embodiments of the present technology will now be described.
[0246] <Modifications of Protective Cover> Fig. 26 schematically shows a holding portion 711 of a protective cover 701, which is a modification of the protective cover. Fig. 26A and Fig. 26B show the state before the insertion portion 711A of the holding portion 711 is rotated. Fig. 26C and Fig. 26D show the state after the insertion portion 711A of the holding portion 711 is rotated.
[0247] For ease of understanding, the protective portion of the protective cover is omitted from the drawing.
[0248] The holding portion 711 includes an insertion portion 711A, positioning keys 711B-1 and 711B-2, and operation keys 711C-1 and 711C-2.
[0249] The positioning keys 711B-1 and 711B-2 are arranged at opposing positions on the side surface of the insertion portion 711A.
[0250] The operation key 711C-1 is formed below the positioning key 711B-1 and is connected to the positioning key 711B-1 before the insertion part 711A is rotated. The operation key 711C-2 is formed below the positioning key 711B-2 and is connected to the positioning key 711B-2 before the insertion part 711A is rotated.
[0251] In contrast, when the insertion portion 711A is rotated around an axis passing through the infusion needle 121, the connection between the positioning key 711B-1 and the operation key 711C-1 and the connection between the positioning key 711B-2 and the operation key 711C-2 are destroyed. As a result, the positioning key 711B-1 and the operation key 711C-1 are separated, and the positioning key 711B-2 and the operation key 711C-2 are separated, and the positioning keys 711B-1 and 711B-2 rotate together with the insertion portion 711A. This changes the relative positions of the positioning key 711B-1 and the operation key 711C-1 in the rotational direction, and the relative positions of the positioning key 711B-2 and the operation key 711C-2 in the rotational direction.
[0252] Hereinafter, when there is no need to distinguish between the positioning keys 711B-1 and 711B-2, they will simply be referred to as the positioning keys 711B. Hereinafter, when there is no need to distinguish between the operation keys 711C-1 and 711C-2, they will simply be referred to as the operation keys 711C.
[0253] FIG. 27 is a schematic diagram showing an example of the configuration of a cover 751 of an injection jig corresponding to the protective cover 701. In FIG.
[0254] In the cover 751, the orientation of the positioning key 711B that can move the injection tool including the injection tip 111 and the protective cover 701 downward is different between the first injection position and the second injection position.
[0255] For example, when the cover 751 is in the first injection position, the injection device cannot be moved downward unless the positioning key 711B and the operation key 711C are facing in the same direction. In other words, unless the positioning key 711B and the operation key 711C are facing in the same direction, the injection needle 121 cannot be inserted into the injection port 104A of the test chip 104.
[0256] In contrast, when the cover 751 is in the second injection position, the injection device cannot be moved downward unless the positioning key 711B faces in a direction rotated 90 degrees relative to the operation key 711C. In other words, the injection needle 121 cannot be inserted into the injection port 104A of the test chip 104 unless the positioning key 711B and the operation key 711C face in different directions.
[0257] Therefore, for example, in the first injection position, it is necessary to rotate the insert 711A of the protective cover 701 to break the connection between the positioning key 711B and the operation key 711C and change the orientation of the positioning key 711B.
[0258] This prevents the puncture order from being incorrect.
[0259] Although not shown in the figures, for example, in the cover of the injection jig, when the injection needle 121 is inserted into the injection port 104A of the test chip 104 at the first injection position, the obstruction to the path to the second injection position is destroyed, the guide part to the second injection position is released, and the injection device can be moved to the second injection position.
[0260] Although not shown, for example, the positioning key of the protective cover may be deformed. For example, in the cover of the injection jig, when the injection needle 121 is inserted into the injection port 104A of the test chip 104 at the first injection position, a part of the positioning key may be fixed to the cover, causing the positioning key to be deformed. Then, the positioning key may be configured so that it cannot be inserted into the positioning part at the second injection position until after the deformation.
[0261] In this way, mistakes in the puncturing order are prevented.
[0262] <Method of Marking Puncture Position> Next, an example of a method of marking the position punctured by the infusion needle 121 will be described with reference to FIGS. 28 to 30. FIG.
[0263] FIG. 28 is a schematic diagram showing an example in which the protective cover 112 described above with reference to FIG. 2 and the like is used.
[0264] In this example, as shown in A of Fig. 28, ink is applied in advance to a position of the protective cover 112 that will come into contact with the test chip 104 (for example, the lower end of the holding part 151) when the injection needle 121 is inserted into the test chip 104. Then, as shown in B of Fig. 28, when the injection needle 121 is inserted into the injection port 104A or 104B of the test chip 104, ink is applied around the injection port 104A or 104B as if it were stamped, as shown in C of Fig. 28.
[0265] This allows the user to easily grasp the position of the punctured injection port on the test chip 104.
[0266] FIG. 29 is a schematic diagram showing an example in which the protective cover 112 described above with reference to FIG. 2 and the like and the cover 351 described above with reference to FIG. 11 and the like are used.
[0267] In this example, as shown in A of Fig. 29, ink is applied in advance to the lower end of the positioning key 151B of the protective cover 112. Then, as shown in B of Fig. 29, when the injection needle 121 is inserted into the test chip 104 and the positioning key 151B of the protective cover 112 comes into contact with the positioning portion 351B or the positioning portion 351C of the cover 351, ink is applied to the positioning portion 351B or the positioning portion 351C as if it were stamped, as shown in C of Fig. 29.
[0268] This allows the user to easily grasp the position of the punctured injection port on the test chip 104.
[0269] FIG. 30 schematically shows an example in which the protective cover 112 described above with reference to FIG. 2 and the like and a cover 801 constituting the injection jig are used.
[0270] A marker 801C is arranged on the cover 801. Before the injection needle 121 is inserted into the injection port 104A of the test chip 104, the marker 801C is covered by the movable part 801B. Then, when the positioning keys 151B-1 and 151B-2 of the protective cover 112 are inserted into the positioning parts 801A-1 and 801A-2 of the cover 801 and the injection needle 121 is inserted into the injection port 104A of the test chip 104, the movable part 801B moves downward together with the positioning key 151B-1. This exposes the marker 801C, making it visible to the user.
[0271] Thereafter, the movable part 801B is fixed to the positioning part 801A-1, and even when the positioning keys 151B-1 and 151B-2 of the protective cover 112 are removed from the positioning parts 801A-1 and 801A-2 of the cover 801, the marker 801C remains exposed.
[0272] This allows the user to easily grasp the position of the punctured injection port on the test chip 104.
[0273] <Method of injecting suspension without using injection bottle 102> Next, with reference to Figures 31 to 33, an example of a method of injecting suspension into the test chip 104 using an injection device 101 directly from a commercially available sample tube without using an injection bottle 102 will be described.
[0274] For example, in the example of FIG. 31, a dropper cap 902 and an intermediate adapter 903 are used.
[0275] First, a collected specimen is suspended in a reagent in a commercially available specimen tube 901 .
[0276] Next, the intermediate adapter 903 is attached to the injection tip 111, and the specimen tube 901 with the drip cap 902 attached is attached to the intermediate adapter 903. The injection tip 111 is attached with, for example, the cap 621 described above with reference to FIG.
[0277] The suspension in the specimen tube 901 is filtered by the dropping cap 902 and the intermediate adapter 903 , and injected into the injection tip 111 via the intermediate adapter 903 .
[0278] The suspension injected into the injection tip 111 is injected into the test tip 104 as described above.
[0279] This makes it possible to inject the suspension directly from the specimen tube 901 into the injection tip 111 without using the injection bottle 102 .
[0280] FIG. 32 shows a schematic example of an example in which a suspension is injected directly from a specimen tube 901 into an injection tip 111 using a membrane 931 that is a hydrophobic filter as an intermediate adapter 903 .
[0281] Although not shown, a sample tube 901 is attached above the dropping cap 902 .
[0282] In this example, a cap 621 and a protective cover 932 are attached to the injection tip 111 .
[0283] The protective cover 932 includes a main body 932A, a mounting portion 932B, and a liquid surface window 932C.
[0284] The main body 932A is cylindrical and surrounds the injection tip 111.
[0285] The mounting portion 932B is formed to extend above the main body portion 932A and has a claw at its tip. The mounting portion 932B is used to protect the membrane 931 and the dropping cap 902 when they are attached to the injection tip 111.
[0286] The liquid surface window 932C is a transparent window formed on the side surface of the main body 932A. The liquid surface window 932C is used to check the amount of suspension in the injection tip 111, for example.
[0287] For example, a dropper cap 902 is inserted into the opening above the membrane 931 .
[0288] The membrane 931 with the dropping cap 902 inserted is inserted into the opening of the injection tip 111. In this state, the flange of the dropping cap 902 is fixed by the claws at the tip of the attachment portion 932B of the protective cover 932. This stabilizes the positions of the membrane 931 and dropping cap 902 relative to the injection tip 111, preventing the membrane 931 and dropping cap 902 from moving or coming off.
[0289] Then, for example, the suspension in the specimen tube 901 is filtered by the dropping cap 902 and the membrane 931 and injected into the injection tip 111 .
[0290] The suspension injected into the injection tip 111 is injected into the test tip 104 as described above.
[0291] This makes it possible to inject the suspension directly from the specimen tube 901 into the injection tip 111 without using the injection bottle 102 .
[0292] Furthermore, the water-stopping effect of membrane 931 prevents the suspension injected into injection tip 111 from spilling out. Even if the suspension spills out of injection tip 111, protective cover 932 prevents the suspension from leaking out.
[0293] <Modification of Membrane> FIG. 33 is a schematic diagram showing an example of the external configuration of a membrane 961 which is a modification of the membrane 931. As shown in FIG.
[0294] The membrane 961 differs from the membrane 931 in that a flange 961A is formed surrounding the side surface of the membrane 961. The flange 961A is formed on the side surface of the membrane 961 at a position close to the side that is inserted into the injection tip 111.
[0295] Furthermore, the membrane 961 is longer in the insertion direction than the membrane 931 .
[0296] When the membrane 961 is inserted into the injection tip 111, the flange 961A serves as a stopper, and the membrane 961 is fixed in place while being inserted into the injection tip 111 by a certain amount.
[0297] Furthermore, the flange 961A improves the waterproofing performance, and the suspension inside the injection tip 111 can be more effectively prevented from spilling out.
[0298] Furthermore, the length of the membrane 961 on the dropping cap 902 side is longer than that of the membrane 931. This increases the surface area of the membrane 931 relative to the dropping cap 902, reduces pressure loss, and makes it possible to easily insert the dropping cap 902 into the membrane 961.
[0299] For example, the protective cover 932 in FIGS. 32 and 33 may be provided with a function for protecting the injection needle 121, like the protective cover 112 or protective cover 511 described above.
[0300] <Other Modifications> The present technology can also be applied to cases where injection needles are inserted into three or more injection ports of a test chip, for example.
[0301] This technology can also be applied to cases where the injection needle is inserted into the injection port of the test chip in a direction other than the up-and-down direction, for example.
[0302] For example, the injection port that is punctured first in the test chip does not necessarily have to be for removing air from the injection needle.
[0303] This technology can also be applied to cases where, for example, liquids other than suspensions are injected into test chips.
[0304] For example, an elastic body other than the leaf spring or coil spring described above may be used for the protective cover. Furthermore, a method for making the protective cover elastic may be used other than the above-described destruction or rotation of the ribs.
[0305] The shape of the injection device described above is basically symmetrical. Therefore, for example, when inserting the injection device into the cover of the injection jig, it is possible to insert the injection device in a state rotated 180 degrees in the circumferential direction from the example described above.
[0306] <<5. Others>> In this specification, a system refers to a collection of multiple components (devices, modules (components), etc.), regardless of whether all of the components are contained in the same housing. Therefore, multiple devices housed in separate housings and connected via a network, and a single device housed in a single housing with multiple modules, are both systems.
[0307] Furthermore, the embodiments of the present technology are not limited to the above-described embodiments, and various modifications are possible within the scope of the gist of the present technology.
[0308] <Examples of Combinations of Configurations> The present technology can also have the following configurations.
[0309] (1) An injection tool comprising: a first positioning unit that aligns the position of an injection tool that injects a liquid into a microchip using an injection needle to a first position corresponding to a first injection inlet of the microchip; and a second positioning unit that aligns the position of the injection tool to a second position corresponding to a second injection inlet of the microchip. (2) The injection tool according to (1), further comprising a guide unit that defines a path of the injection tool between at least the first position and the second position. (3) The injection tool according to (2), wherein the guide unit comprises: a first guide unit that, at the first position, guides the injection tool in a first movement direction that moves the injection needle closer to or away from the first injection inlet; a second guide unit that, at the second position, guides the injection tool in a second movement direction that moves the injection needle closer to or away from the second injection inlet; and a third guide unit that guides the injection tool to move between the first position and the second position. (4) The injection jig according to (3), wherein the injection device can be moved to the first guide section without passing through the third guide section, and the injection device cannot be moved to the second guide section without passing through the third guide section. (5) The injection jig according to (3) or (4), wherein the distance between the third guide section and the first injection port at the first position is longer than the distance between the third guide section and the first injection port at the second position. (6) The injection jig according to (5), wherein the injection device cannot move the injection needle in the direction that the injection needle extends before a predetermined operation is performed, and can move the injection needle in the direction that the injection needle extends after the predetermined operation is performed. (7) The injection jig according to any one of (3) to (6), wherein the injection device includes a positioning key that is used to position the injection device and is rotatable around an axis passing through the injection needle, and a first direction of the positioning key that allows the injection device to move in the first movement direction in the first guide section is different from a second direction of the positioning key that allows the injection device to move in the second movement direction in the second guide section.(8) The injection jig according to (7), wherein the positioning key faces the first direction before a predetermined portion of the injection device is destroyed. (9) The injection jig according to any of (3) to (8), wherein the first movement direction and the second movement direction are up and down directions. (10) The injection jig according to any of (2) to (9), wherein the injection device includes an operation key used to move the injection device, and the guide section defines a path of the operation key. (11) The injection jig according to any of (1) to (10), wherein the first positioning section and the second positioning section include positioning keys used to position the injection device. (12) The injection jig according to (11), further comprising a slide mechanism that moves the injection device between the first position and the second position. (13) The injection jig according to (12), wherein at the first position, the positioning key is movable between the slide mechanism and the first positioning part, and at the second position, the positioning key is movable between the slide mechanism and the second positioning part. (14) The injection jig according to (13), wherein the slide mechanism does not slide between the first position and the second position when the positioning key is disposed in the first positioning part or the second positioning part. (15) The injection jig according to (13) or (14), wherein the distance between the slide mechanism and the first injection inlet at the first position is longer than the distance between the slide mechanism and the first injection inlet at the second position. (16) The injection jig according to any of (1) to (15), comprising: a base on which the microchip is placed; and a cover that is placed on the base. (17) The injection jig according to (1), wherein the first injection port is used to remove air from the injection needle, and the second injection port is used to inject the liquid into the microchip.
[0310] (A1) A protective cover comprising: a holding part that holds an injection needle; a protective part that is arranged relative to the holding part in a first direction in which the injection needle extends and that covers at least a portion of the periphery of the tip of the injection needle; a fixing mechanism that fixes the position of the holding part in the first direction relative to the protective part and that is capable of releasing the fixed position of the holding part by a predetermined operation; and an elastic body that applies an elastic force to the holding part in a second direction opposite to the first direction when the holding part is moved in the first direction relative to the protective part. (A2) The protective cover described in (A1) above, in which the tip of the injection needle is exposed outside the protective part when the holding part is moved in the first direction relative to the protective part. (A3) The protective cover described in (A2) above, in which the elastic force moves the holding part in the second direction when the force moving the holding part in the first direction is released, and the tip of the injection needle returns inside the protective part. (A4) The protective cover described in (A2) or (A3) above, in which the injection needle is used to inject liquid into a microchip. (A5) The protective cover according to (A4), further comprising a positioning key used to position the protective cover in an injection jig used to inject liquid into the microchip. (A6) The protective cover according to (A5), further comprising an operation key used to move the protective cover in the injection jig. (A7) The protective cover according to (A5) or (A6), which attaches a marking to at least one of the microchip and the injection jig when the injection needle is inserted into the injection port of the microchip using the injection jig. (A8) The protective cover according to any of (A1) to (A7), wherein the fixing mechanism includes a rib connecting the holding part and the protective part, and wherein the fixing of the position of the holding part is released when the rib is broken. (A9) The protective cover according to any of (A1) to (A7), wherein the fixing of the position of the holding part by the fixing mechanism is released when the holding part is rotated around an axis passing through the injection needle.(A10) The protective cover according to (A9), further comprising: a positioning key used to position the protective cover in an injection jig used to inject liquid into a microchip using the injection needle; and an operation key used to move the protective cover in the injection jig, wherein rotation of the holding part changes the relative positions of the positioning key and the operation key in the rotational direction. (A11) The protective cover according to any of (A1) to (A10), wherein the elastic body is a leaf spring. (A12) The protective cover according to any of (A1) to (A11), wherein the elastic body is a coil spring. (A13) An injection device comprising: an injection needle; and a protective cover, wherein the protective cover comprises: a holding part that holds the injection needle; a protective part that is arranged in a first direction in which the injection needle extends relative to the holding part and covers at least a part of the periphery of the tip of the injection needle; a fixing mechanism that fixes the position of the holding part in the first direction relative to the protective part and can release the fixed position of the holding part by a predetermined operation; and an elastic body that applies an elastic force to the holding part in a second direction opposite to the first direction when the holding part is moved in the first direction relative to the protective part.
[0311] The effects described in this specification are merely examples and are not limiting, and other effects may also be present.
[0312] 101 Injection tool, 102 Injection bottle, 103 Injection jig, 104 Inspection chip, 104A, 104B Injection port, 111 Injection chip, 112 Protective cover, 121 Injection needle, 151 Holding portion, 151B-1, 151B-2 Positioning key, 151C-1, 151C-2 Rib, 151D-1, 151D-2 Operation key, 152 Protective portion, 153-1, 153-2 Leaf spring, 302 Cover, 302B, 302C Positioning portion, 351 Cover, 351B-1, 351B-2 Positioning portion, 351C-1, 351C-2 Positioning portion, 351D-1 to 351F-2 Guide portion, 401 Cover, 411B-1 to 411E-2 Guide portion, 412 Adapter, 412B-1, 412B-2 Positioning portion, 412C-1, 412C-2 Guide portion, 501 Injection device, 511 Protective cover, 521 Holding member, 521B-1, 521B-2 Positioning key, 521C-1, 521C-2 Operation key, 521E-1, 521E-2 Stopper, 522 Protective member, 522C-1, 522C-2 Operation key, 523 Coil spring, 551 Cover, 551B to 551K-2 Guide portion, 551L-1 to 551M-2 Positioning portion, 601 Injection device, 611 Protective cover, 621 Cap, 651 Cover, 651A Guide portion, 701 Protective cover, 711 Holding portion, 711B-1, 711B-2 Positioning keys, 711C-1, 711C-2 Operation keys, 751 Cover
Claims
1. An injection tool comprising: a first positioning unit that aligns the position of an injection tool, which injects liquid into a microchip using an injection needle, to a first position corresponding to a first injection port of the microchip; and a second positioning unit that aligns the position of the injection tool to a second position corresponding to a second injection port of the microchip.
2. The injection tool according to claim 1, further comprising a guide portion defining a path of said injection tool between at least said first position and said second position.
3. The injection jig according to claim 2, wherein the guiding portion comprises: a first guiding portion that, at the first position, guides the injection device in a first movement direction to move the injection needle toward or away from the first injection port; a second guiding portion that, at the second position, guides the injection device in a second movement direction to move the injection needle toward or away from the second injection port; and a third guiding portion that guides the injection device to move between the first position and the second position.
4. The injection tool according to claim 3, wherein the injection tool can be moved to the first guide section without passing through the third guide section, and the injection tool cannot be moved to the second guide section without passing through the third guide section.
5. The injection tool according to claim 3, wherein the distance between the third guide portion and the first injection port at the first position is longer than the distance between the third guide portion and the first injection port at the second position.
6. The injection tool according to claim 5, wherein the injection instrument is such that the injection needle cannot be moved in the direction in which the injection needle extends before a predetermined operation is performed, and the injection instrument is such that the injection needle can be moved in the direction in which the injection needle extends after the predetermined operation is performed.
7. The injection jig according to claim 3, wherein the injection device is provided with a positioning key used for positioning the injection device and rotatable around an axis passing through the injection needle, and a first direction of the positioning key which enables the injection device to move in the first movement direction in the first guiding section is different from a second direction of the positioning key which enables the injection device to move in the second movement direction in the second guiding section.
8. The injection tool according to claim 7, wherein the positioning key faces the first direction before a predetermined portion of the injection device is destroyed.
9. The injection jig according to claim 3, wherein the first movement direction and the second movement direction are vertical directions.
10. The injection tool according to claim 2, wherein the injection tool includes an operation key used to move the injection tool, and the guide portion defines a path for the operation key.
11. The injection jig according to claim 1, wherein the first positioning portion and the second positioning portion are provided with positioning keys used for positioning the injection device.
12. The injection tool according to claim 11, further comprising a slide mechanism for moving the injection device between the first position and the second position.
13. An injection jig as described in claim 12, wherein, at the first position, the positioning key is movable between the slide mechanism and the first positioning portion, and, at the second position, the positioning key is movable between the slide mechanism and the second positioning portion.
14. The injection jig according to claim 13, wherein the slide mechanism does not slide between the first position and the second position when the positioning key is disposed in the first positioning portion or the second positioning portion.
15. The injection tool according to claim 13, wherein the distance between the slide mechanism and the first injection port at the first position is longer than the distance between the slide mechanism and the first injection port at the second position.
16. The injection jig according to claim 1, comprising: a base on which the microchip is placed; and a cover that is placed on the base.
17. The injection tool according to claim 1, wherein the first injection port is used to remove air from the injection needle, and the second injection port is used to inject the liquid into the microchip.
Citation Information
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