Solid water-in-oil-type cosmetic

Abstract

Provided is a solid water-in-oil-type cosmetic in which the structure of the cosmetic itself remains intact even when being blended with a vesicle composition, which has excellent temporal stability, and which provides excellent temporal stability for the vesicle composition. This solid water-in-oil-type cosmetic contains at least: component (A) which is a vesicle composition; component (B) which is an oily gelling agent; and component (C) which is a lipophilic surfactant.

Description

Solid water-in-oil cosmetics

[0001] The present technology relates to a solid water-in-oil cosmetic preparation.

[0002] Vesicle (liposome) compositions, which are spherical closed endoplasmic reticulum formed in an aqueous solvent by the action of amphiphilic substances such as phospholipids and surfactants, are widely used in the pharmaceutical field as a skin care base material for the purpose of delivering active ingredients and in the cosmetic field as a skin care base material for the purpose of achieving a stratum corneum retention effect. Furthermore, water-in-oil cosmetics, due to their structural characteristics in which the oil phase is a continuous phase, are known to have the advantage of leaving an oil film on the skin with moisture-occlusive properties, protecting the skin from dryness for a long period of time, and maintaining the stability of ingredients with stability concerns, such as water-soluble drugs and cosmetic ingredients. Given this current situation, technology for incorporating vesicle compositions into water-in-oil cosmetics has attracted attention.

[0003] For example, Patent Document 1 discloses a water-in-oil emulsion-type topical skin preparation that contains an organically modified clay mineral and a hydroxylated phospholipid, and that contains the hydroxylated lecithin in the form of small spheres in the aqueous phase. The patent document also discloses a technology that enhances the transdermal absorbability of water-soluble active ingredients, even though the preparation is in the form of a water-in-oil emulsion.

[0004] Japanese Patent Application Laid-Open No. 2007-308380

[0005] However, as described above, liquid water-in-oil cosmetics with a high water content are subject to concerns about reduced occlusiveness and increased dryness, leading to a desire for solid water-in-oil cosmetics such as balms. However, when a vesicle composition is incorporated into a solid water-in-oil cosmetic, the oil or oily gelling agent destroys the outer phase (oil phase) that maintains the cosmetic in a solid state, causing the inner layer (aqueous phase) and oil to ooze out of the cosmetic, a phenomenon known as "drainage," resulting in the cosmetic not solidifying. This is thought to be because the surfactant in the vesicle composition inhibits the solidification of the gelling agent, causing the oil to ooze into the aqueous phase without solidifying, further destabilizing the dispersion state of the aqueous phase and promoting coalescence of the aqueous phase, resulting in the aqueous phase also oozing into the oil phase. Currently, no studies have been reported on the formulation of solid water-in-oil cosmetics containing a vesicle composition.

[0006] The main objective of this technology is to provide a technology relating to a solid water-in-oil cosmetic that does not destroy the structure of the cosmetic itself even when a vesicle composition is incorporated, has excellent stability over time, and also provides excellent stability of the vesicle composition over time.

[0007] The present inventors have conducted extensive research to solve the above-mentioned problems, and as a result have found that by using a combination of an oily gelling agent and a lipophilic surfactant in a solid water-in-oil cosmetic containing a vesicle composition, it is possible to obtain a solid water-in-oil cosmetic that does not lose its structure even when the vesicle composition is incorporated, has excellent stability over time, and also has excellent stability of the vesicle composition over time, and thus has completed the present technology.

[0008] That is, the present technology provides a solid water-in-oil cosmetic containing at least: component (A) a vesicle composition; component (B) an oily gelling agent; and component (C) a lipophilic surfactant. The present technology also provides the solid water-in-oil cosmetic in which component (A) is a liposome composition. The present technology also provides the solid water-in-oil cosmetic in which component (A) is a liposome composition containing at least: component (a1) a phospholipid; component (a2) a sterol; and component (a3) ​​a polyhydric alcohol. The present technology also provides the solid water-in-oil cosmetic in which component (B) contains at least (b1) a wax. The present technology also provides the solid water-in-oil cosmetic in which the content of component (b1) is 1 to 30% by mass relative to the total amount of the cosmetic. The present technology also provides the solid water-in-oil cosmetic, in which the component (B) contains (b1) a wax and (b2) an oil-based gelling agent other than a wax. The present technology also provides the solid water-in-oil cosmetic, in which the component (b2) is at least one selected from the group consisting of dextrin fatty acid esters, sucrose fatty acid esters, inulin fatty acid esters, 12-hydroxystearic acid, metal soaps, organically modified clay minerals, amino acid-based gelling agents, and inorganic powders. The present technology also provides the solid water-in-oil cosmetic, in which the component (b2) is an inorganic powder. The present technology also provides the solid water-in-oil cosmetic, in which the component (D) is a glycerin fatty acid ester (excluding component (C)). The present technology also provides the solid water-in-oil cosmetic, in which the water content is 80% by mass or less relative to the total amount of the cosmetic. The present technology also provides the solid water-in-oil cosmetic, wherein the cosmetic has a penetration load value of 50 to 500 gf. Furthermore, the present technology also provides the solid water-in-oil cosmetic, wherein the cosmetic is a skin care cosmetic. Furthermore, the present technology also provides the solid water-in-oil cosmetic, wherein the cosmetic is a lip cosmetic.

[0009] According to the present technology, by using a combination of an oily gelling agent and a lipophilic surfactant in a solid water-in-oil cosmetic containing a vesicle composition, it is possible to provide a solid water-in-oil cosmetic that does not lose its structure even when the vesicle composition is incorporated, has excellent stability over time, and also has excellent stability of the vesicle composition over time. Furthermore, the solid water-in-oil cosmetic of the present technology also has excellent usability, such as occlusive properties, ease of removal (easy removal with fingers), and good spreadability.

[0010] The present technology (the present invention) will be described in detail below. However, the present technology is not limited to the following embodiments. In this specification, "X to Y" indicating a range includes the numerical values ​​X and Y before and after it, and means "X or more and Y or less." Furthermore, the upper limit (or less) and the lower limit (or more) of each numerical range (to) can be arbitrarily combined as desired.

[0011] The present technology relates to a solid water-in-oil cosmetic containing a vesicle composition, which contains at least an oily gelling agent and a lipophilic surfactant.

[0012] [Solid Water-in-Oil Cosmetic] The solid water-in-oil cosmetic according to the present technology refers to a water-in-oil cosmetic that is solid at room temperature (25°C). "Solid at room temperature (25°C)" means that the cosmetic does not become fluid when filled in a container and left to stand. Furthermore, the water-in-oil cosmetic refers to a cosmetic that has an oil phase as its external phase and an aqueous phase as its internal phase. The oil phase contains an oily component (e.g., an oil or an oily gelling agent, etc.), and the aqueous phase contains an aqueous component (e.g., a vesicle composition, water, alcohols, etc.). Any cosmetic in which the aqueous phase is dispersed in the oil phase may be used, including water-in-oil emulsion cosmetics. From the viewpoint of the stability over time of the water-in-oil cosmetic and the vesicle composition, the solid water-in-oil cosmetic according to the present technology is preferably a solid water-in-oil emulsion cosmetic.

[0013] [Component (A) Vesicle Composition] In the present technology, the vesicle composition of component (A) refers to a closed endoplasmic reticulum having a bilayer membrane structure, and includes a vesicle composition dispersion obtained by dispersing the vesicle composition in an aqueous solvent. Furthermore, the "vesicle composition" according to the present technology includes a "unilamellar vesicle" having a single-layer bilayer membrane structure and a "multilamellar vesicle" having a multilayer bilayer membrane structure. The multilamellar vesicle is one in which a Maltese cross image is observed under a polarizing microscope, or alternatively, one observed under a transmission electron microscope. In the present technology, a multilamellar vesicle is more preferred. Compared to a unilamellar vesicle, a multilamellar vesicle can encapsulate a larger amount of active ingredient or drug (preferably an oil-soluble active ingredient and / or drug), and is also expected to have skin benefits due to the vesicle components such as phospholipids and sterols, which will be described later.

[0014] The vesicle composition used in the present technology is not particularly limited, and any can be used as long as it is used in ordinary cosmetics, topical skin preparations, etc. The vesicle compositions used in the present technology can be classified into nonionic vesicles, anionic vesicles, and cationic vesicles depending on the ionicity of the amphiphilic substance used.

[0015] The nonionic vesicles used in the present technology are composed of nonionic surfactants having a hydroxy group (-OH) or an ether bond (-O-) in the hydrophilic group, which do not dissociate into ions (do not become ions) even when dissolved in water. The nonionic surfactants used in the present technology are not particularly limited as long as they are used in ordinary cosmetics, but from the viewpoint of forming a vesicle composition, for example, polyoxyethylene sterol ethers and sucrose fatty acid esters are preferred.

[0016] From the viewpoint of the stability of the vesicle composition over time, the nonionic vesicles used in the present technology are preferably a combination of the above-mentioned nonionic surfactants and one or more sphingosines selected from the group consisting of sterols, monoalkylglyceryls, and ceramides.

[0017] The anionic vesicles used in the present technology are composed of an amphoteric surfactant or anionic surfactant having a hydrophilic group that ionizes in water and exhibits anionic properties and a hydrophobic group such as a fatty acid. There are no particular limitations on the amphoteric surfactant or anionic surfactant used in the present technology, as long as it exhibits anionic properties in the composition. While any amphoteric surfactant or anionic surfactant commonly used in cosmetics can be used without particular limitations, from the perspective of forming a vesicle composition, phospholipids and acyl glutamates are preferred. Examples of acyl glutamates include sodium dilauroyl glutamate lysine, N-lauroyl-L-glutamic acid, N-myristoyl-L-glutamic acid, N-palmitoyl-L-glutamic acid, N-stearoyl-L-glutamic acid, and N-coconut oil fatty acid acyl-L-glutamic acid.

[0018] From the viewpoint of the stability of the vesicle composition over time, the anionic vesicle used in the present technology is preferably a combination of the above-mentioned anionic surfactant and one or more sphingosines selected from the group consisting of sterols, monostearylglyceryl ether, and ceramides.

[0019] The cationic vesicles used in the present technology are composed of a cationic surfactant having a hydrophilic group that undergoes ionization in water and exhibits cationic properties and a hydrophobic group such as a fatty acid, and are not particularly limited as long as they exhibit cationic properties in the composition. The cationic surfactants used in the present technology are not particularly limited as long as they are those used in ordinary cosmetics, and examples thereof include quaternary ammonium salts, tertiary amines, fatty acid amidoamines and their neutralized products, ester amines, etc. Furthermore, examples of structures having a hydrophobic group such as a fatty acid include mono-long chain alkyl types, di-long chain alkyl types, and ethylene oxide adduct types. Examples of hydrophilic groups exhibiting cationic properties include ammonium salts and benzalkonium salts. Examples of counter ions include chloride ions, bromide ions, methyl sulfate ions, and ethyl sulfate ions.

[0020] In the present technology, the cationic surfactant constituting the cationic vesicle is preferably a dilong-chain cationic surfactant from the viewpoint of forming a vesicle composition, and more preferably a dilong-chain cationic surfactant having two fatty acid chains and an ester bond in the hydrophobic chain. Furthermore, from the viewpoint of the stability over time of the vesicle composition, dilong-chain acylalkylhydroxyalkylammonium is more preferred, and one or more cationic surfactants selected from the group consisting of dicocoyl ethyl hydroxyethylmonium methosulfate and dipalmitoyl ethyl hydroxyethylmonium methosulfate are particularly preferred. Commercially available products include DEHYQUATL80T (manufactured by BASF: pure content 80%), which is a mixture of dicocoyl ethyl hydroxyethylmonium methosulfate, and DEHYQUARTA U56 / G and DEHYQUARTC4046 (both manufactured by BASF), which are mixtures of dipalmitoyl ethyl hydroxyethylmonium methosulfate, and the like, and one or more of these may be used in combination.

[0021] The mass content of the components constituting the closed endoplasmic reticulum having a bilayer membrane structure of component (A) relative to the total mass of the solid water-in-oil cosmetic is not particularly limited and can be freely set as long as it does not impair the action and effect of the present technology. The lower limit of the mass content of the components constituting the closed endoplasmic reticulum having a bilayer membrane structure of component (A) relative to the total mass of the solid water-in-oil cosmetic is preferably 0.01 mass% or more, more preferably 0.05 mass% or more, even more preferably 0.1 mass% or more, still more preferably 0.2 mass% or more, and particularly preferably 0.3 mass% or more. The upper limit of the mass content of the components constituting the closed endoplasmic reticulum having a bilayer membrane structure of component (A) relative to the total mass of the solid water-in-oil cosmetic is preferably 10 mass% or less, more preferably 5 mass% or less, even more preferably 3 mass% or less, and particularly preferably 2.5 mass% or less. Among these, from the viewpoints of the stability over time of the solid water-in-oil cosmetic and the vesicle composition, the occlusive feeling, the feel when used, and the like, the content by mass of the component constituting the closed endoplasmic reticulum having a bilayer membrane structure of component (A) relative to the total mass of the solid water-in-oil cosmetic is, for example, preferably 0.01 to 10 mass%, more preferably 0.05 to 5 mass%, even more preferably 0.1 to 3 mass%, even more preferably 0.2 to 3 mass%, and particularly preferably 0.3 to 2.5 mass%.

[0022] <Liposome Composition> The vesicle composition used in the solid water-in-oil cosmetic according to the present technology is not particularly limited, but is preferably a liposome composition, which is a spherical closed endoplasmic reticulum formed by a bilayer membrane of phospholipids, from the viewpoints of the temporal stability, penetration sensation, moisturizing properties, etc. of the vesicle composition. Liposomes can encapsulate active ingredients or drugs within their membranes and have high skin retention, allowing the active ingredients or drugs to effectively exert their efficacy, while the phospholipids in the bilayer membrane can provide a highly sustained moisturizing effect. Use of this liposome composition can impart a higher penetration sensation and moisturizing effect to the solid water-in-oil cosmetic according to the present technology. From the viewpoints of the temporal stability of the liposome composition, it is more preferable that the liposome composition used as the vesicle composition of the present technology be a liposome composition containing at least component (a1) a phospholipid, component (a2) a sterol, and component (a3) ​​a polyhydric alcohol.

[0023] (Component (a1) Phospholipid) The phospholipid of component (a1) used in the present technology is used as a constituent of the liposome composition in the present technology, and is not particularly limited as long as it is used in ordinary cosmetics, topical skin preparations, etc., but examples include phosphatidylcholine, phosphatidylethanolamine, phosphatidylserine, phosphatidylglycerol, phosphatidylinositol, sphingophospholipid, etc. These can be used in combination of one or more types appropriately selected as needed. Furthermore, component (a1) may be a composition containing one or more types of phospholipids as described above.

[0024] Examples of sources of component (a1) include soybeans, egg yolks, sunflowers, microorganisms, marine organisms, and animal organs. Among these, phospholipids derived from soybeans are preferred. Examples of phospholipid-containing compositions include soybean lecithin (also referred to as "soybean phospholipid"), egg yolk lecithin (also referred to as "egg yolk phospholipid"), hydrogenated products thereof, and lysolecithins obtained by enzymatically treating these lecithins with lyso-esters. Among these, hydrogenated phospholipids are preferred, and hydrogenated soybean phospholipids are more preferred. These can be used in combination, or one or more types can be appropriately selected as needed. Specific commercial products include HSL-70 (manufactured by YMC Co., Ltd.), NIKKOL Lecinol S-10E (manufactured by Nikko Chemicals Co., Ltd.), Basis LS-60HR (manufactured by Nisshin Oillio Group, Ltd.), and egg yolk lysolecithin LPC-1 (manufactured by Kewpie Corporation).

[0025] In the present technology, the "PC purity" of component (a1) refers to the proportion (purity) of phosphatidylcholine (PC) contained in the phospholipid. The lower limit of the PC purity of component (a1) used in the present technology is, for example, 60% or more, preferably 70% or more, more preferably 75% or more, even more preferably 80% or more, and even more preferably 85% or more. The upper limit of the PC purity of component (a1) used in the present technology is not particularly limited and may be, for example, 99% or less. The PC purity can be analyzed using conventionally known methods such as HPLC (high performance liquid chromatography) and GC (gas chromatography).

[0026] The content of component (a1) in the present technology is not particularly limited and can be freely set as long as it does not impair the action and effect of the present technology. The lower limit of the mass content of component (a1) relative to the total mass of the solid water-in-oil cosmetic is preferably 0.01 mass% or more, more preferably 0.1 mass% or more, even more preferably 0.2 mass% or more, and even more preferably 0.5 mass% or more. The upper limit of the mass content of component (a1) relative to the total mass of the solid water-in-oil cosmetic is preferably 10 mass% or less, more preferably 5 mass% or less, and even more preferably 2 mass% or less. Among these, from the viewpoints of the stability over time, penetration feeling, moisturizing properties, etc. of the liposome composition, the mass content of component (a1) relative to the total mass of the solid water-in-oil cosmetic is, for example, preferably 0.01 to 10 mass%, more preferably 0.1 to 5 mass%, even more preferably 0.2 to 2 mass%, and even more preferably 0.5 to 2 mass%.

[0027] (Component (a2) Sterols) The component (a2) sterols used in the present technology are used as components of the liposome composition together with component (a1) and contribute to the stability of the lipid bilayer structure in the liposome composition. The component (a2) sterols used in the present technology are not particularly limited as long as they are used in ordinary cosmetics, topical skin preparations, etc., and examples thereof include cholesterol and phytosterols. These may be used in combination of one or more types as needed. The cholesterol used in the present technology is generally purified from natural products, and cholesterol purified from any natural product can be used in the present technology. Commercially available products include Kairei Marine Cholesterol (manufactured by Nippon Suisan Kaisha). The phytosterol used in the present technology can be any phytosterol generally classified as a phytosterol (plant sterol), and preferred examples include those containing campesterol, sitosterol, stigmastanol, etc. as components. Such components can be obtained by extracting grain germ or the like with an organic solvent and removing the water-soluble portion, but commercially available products can also be purchased and used, such as Phytosterol QI (manufactured by Mitsubishi Chemical Foods Corporation).

[0028] The content of component (a2) in the present technology is not particularly limited and can be freely set as long as it does not impair the action and effect of the present technology. The lower limit of the content by mass of component (a2) relative to the total mass of the solid water-in-oil cosmetic is preferably 0.01 mass% or more, more preferably 0.03 mass% or more, even more preferably 0.05 mass% or more, and even more preferably 0.1 mass% or more. The upper limit of the content by mass of component (a2) relative to the total mass of the solid water-in-oil cosmetic is preferably 2 mass% or less, more preferably 1 mass% or less, and even more preferably 0.5 mass% or less. Among these, from the viewpoint of the stability over time of the liposome composition, the content by mass of component (a2) relative to the total mass of the solid water-in-oil cosmetic is, for example, preferably 0.01 to 2 mass%, more preferably 0.03 to 1 mass%, even more preferably 0.05 to 1 mass%, even more preferably 0.05 to 0.5 mass%, and particularly preferably 0.1 to 0.5 mass% in the solid water-in-oil cosmetic.

[0029] (Component (a3) ​​Polyhydric Alcohol) The polyhydric alcohol of component (a3) ​​used in the present technology has a structure having two or more hydroxyl groups in the molecule, and contributes to the dispersibility and solubility of components (a1) and (a2) in the present technology. The inclusion of this polyhydric alcohol can improve the stability of the liposome composition over time. The polyhydric alcohol of component (a3) ​​used in the present technology is not particularly limited as long as it is one used in ordinary cosmetics, topical skin preparations, etc., but for example, one having an IOB value in the range of 1.8 to 5.5 can be used, and one or more types can be appropriately selected and combined as needed. In the present technology, from the viewpoint of the stability of the liposome composition over time, it is preferable to use a combination of one having an IOB value in the range of 1.8 to 3.5 and one having an IOB value in the range of 4.5 to 5.5.

[0030] The IOB value in this technology is a value determined based on the Organic Conceptual Diagram (Fujita, Atsushi, Prediction of Organic Compounds and Organic Conceptual Diagram, Chemistry Vol. 11, No. 10 (1957) 719-715). More specifically, this organic conceptual diagram is a value that expresses the physicochemical properties of a compound by defining the degree of properties mainly due to van der Waals forces as "organic" and the degree of properties mainly due to electrical affinity as "inorganic." The IOB value is an index that indicates the balance between inorganic and organic properties, and is expressed as IOB value = inorganic value / organic value. A compound with a larger IOB value is said to exhibit higher hydrophilic and polar properties.

[0031] Examples of polyhydric alcohols having an IOB value in the range of 1.8 to 3.5 include dipropylene glycol (IOB value = 1.8), 1,3-butylene glycol (IOB value = 2.5), 1,3-propanediol (IOB value = 3.3), and diglycerin (IOB value = 3.5). Examples of polyhydric alcohols having an IOB value in the range of 4.5 to 5.5 include glycerin (IOB value = 5.0) and sorbitol (IOB value = 5.0). One or more of the above components can be selected and used as component (a3) ​​as needed. From the viewpoint of the stability over time of the liposome composition, a combination of dipropylene glycol and / or 1,3-butylene glycol with glycerin is preferred, and a combination of 1,3-butylene glycol and glycerin is even more preferred.

[0032] The content of component (a3) ​​in the present technology is not particularly limited and can be freely set as long as it does not impair the action and effect of the present technology. The lower limit of the content by mass of component (a3) ​​relative to the total mass of the solid water-in-oil cosmetic is preferably 0.5% by mass or more, more preferably 1% by mass or more, and even more preferably 4% by mass or more. The upper limit of the content by mass of component (a3) ​​relative to the total mass of the solid water-in-oil cosmetic is preferably 30% by mass or less, more preferably 20% by mass or less, and even more preferably 10% by mass or less. Among these, from the viewpoint of the stability over time of the liposome composition, the content by mass of component (a3) ​​relative to the total mass of the solid water-in-oil cosmetic is, for example, preferably 0.5 to 30% by mass, more preferably 1 to 20% by mass, and even more preferably 4 to 10% by mass.

[0033] When a combination of polyhydric alcohols having an IOB value in the range of 1.8 to 3.5 and polyhydric alcohols having an IOB value in the range of 4.5 to 5.5 are used as component (a3) ​​in the present technology, the content of each polyhydric alcohol is not particularly limited and can be freely set as long as it does not impair the action and effect of the present technology. The lower limit of the content of polyhydric alcohols having an IOB value in the range of 1.8 to 3.5 relative to the total mass of the solid water-in-oil cosmetic is preferably 0.05% by mass or more, more preferably 0.1% by mass or more, even more preferably 1% by mass or more, and particularly preferably 2% by mass or more. The upper limit of the content by mass of polyhydric alcohols having an IOB value in the range of 1.8 to 3.5 relative to the total mass of the solid water-in-oil cosmetic is preferably 10% by mass or less, more preferably 8% by mass or less, even more preferably 6% by mass or less, and particularly preferably 5% by mass or less. Among these, the content of polyhydric alcohols having an IOB value in the range of 1.8 to 3.5 relative to the total mass of the solid water-in-oil cosmetic is, for example, preferably 0.05 to 10% by mass, more preferably 0.1 to 8% by mass, even more preferably 1 to 6% by mass, and particularly preferably 2 to 5% by mass. Furthermore, the lower limit of the content of polyhydric alcohols having an IOB value in the range of 4.5 to 5.5 relative to the total mass of the solid water-in-oil cosmetic is preferably 0.05% by mass or more, more preferably 0.1% by mass or more, even more preferably 1% by mass or more, and particularly preferably 2% by mass or more. The upper limit of the content of polyhydric alcohols having an IOB value in the range of 4.5 to 5.5 relative to the total mass of the solid water-in-oil cosmetic is preferably 10% by mass or less, more preferably 8% by mass or less, and even more preferably 5% by mass or less. Among these, the content of polyhydric alcohols having an IOB value in the range of 4.5 to 5.5 relative to the total mass of the solid water-in-oil cosmetic is preferably 0.05 to 10% by mass, more preferably 0.1 to 8% by mass, even more preferably 1 to 5% by mass, and particularly preferably 2 to 5% by mass. The ratio of the content of each polyhydric alcohol (polyhydric alcohols having an IOB value in the range of 1.8 to 3.5:polyhydric alcohols having an IOB value in the range of 4.5 to 5.5) is preferably 0.5 to 9.5:9.5 to 0.5, more preferably 1 to 5:5 to 1.

[0034] As described above, the vesicle (liposome) composition according to the present technology exists in a dispersed state in an aqueous solvent, and therefore can contain, as the aqueous solvent, one or more aqueous components selected from water, lower alcohols (preferably having 1 to 4 carbon atoms, for example, EtOH), etc. In addition to the essential components of components (A) to (C), the vesicle (liposome) composition can appropriately contain one or more components selected from oils, surfactants, water-soluble polymers, various cosmetic active ingredients, fragrances, etc., within the scope that does not impair the structure of the vesicle (liposome) composition.

[0035] The method for producing the vesicle (liposome) composition according to the present technology is not particularly limited, and preparation can be performed by a commonly used production method. In the case of a liposome composition, for example, components (a1) to (a3) ​​are preheated and mixed uniformly, and a heated aqueous component is then added thereto while stirring to obtain a liposome composition dispersion. The mixing temperature is not particularly limited, but examples include 60 to 80°C. The obtained liposome composition dispersion may then be subjected to high-pressure treatment. The dispersion thus obtained is observed under a polarizing microscope under crossed Nicols, and the formation of a liposome composition can be confirmed by checking the Maltese cross image.

[0036] The average particle size of the vesicle (liposome) composition according to the present technology is not particularly limited, but is preferably 50 to 600 nm, and more preferably 70 to 500 nm, from the viewpoints of the stability over time, penetration feeling, moisturizing property, etc. of the vesicle (liposome) composition. The average particle size can be measured using a real-time nanoparticle size measurement device, DelsaMaxCORE (manufactured by Beckman Coulter, Inc.).

[0037] [Component (B) Oil-Based Gelling Agent] Component (B) oil-based gelling agent used in the present technology is a component that renders water-in-oil cosmetic compositions non-fluid. By including this component, the water-in-oil cosmetic composition is solidified, improving the stability over time of the water-in-oil cosmetic composition and vesicle composition, as well as improving the usability, such as occlusiveness, ease of removal, and good spreadability. Component (B) oil-based gelling agents used in the present technology are divided into (b1) wax and (b2) oil-based gelling agents other than wax, depending on their gelling mechanism. From the viewpoints of solidifying the water-in-oil cosmetic composition, the stability over time, occlusiveness, and usability of the water-in-oil cosmetic composition and vesicle composition, it is preferable that component (B) used in the present technology contains at least (b1) wax, and more preferably contains (b1) wax and (b2) oil-based gelling agents other than wax.

[0038] The mass content of component (B) relative to the total mass of the solid water-in-oil cosmetic is not particularly limited and can be freely set as long as it does not impair the action and effect of the present technology. The lower limit of the mass content of component (B) relative to the total mass of the solid water-in-oil cosmetic is preferably 1 mass% or more, more preferably 2 mass% or more, even more preferably 3 mass% or more, and particularly preferably 6 mass% or more. The upper limit of the mass content of component (B) relative to the total mass of the solid water-in-oil cosmetic is preferably 30 mass% or less, more preferably 25 mass% or less, even more preferably 22 mass% or less, and even more preferably 18 mass% or less. Among these, from the viewpoints of solidification of the water-in-oil cosmetic, and the stability over time of the water-in-oil cosmetic and the vesicle composition, the content by mass of component (B) relative to the total mass of the solid water-in-oil cosmetic is, for example, preferably 1 to 30 mass%, more preferably 2 to 25 mass%, even more preferably 3 to 22 mass%, even more preferably 6 to 22 mass%, and particularly preferably 6 to 18 mass%.

[0039] Furthermore, the mass ratio (a1) / (B) of component (a1) to component (B) is not particularly limited and can be freely set as long as it does not impair the functions and effects of the present technology. The lower limit of (a1) / (B) is preferably 0.01 or more, more preferably 0.02 or more, and even more preferably 0.022 or more. The upper limit of (a1) / (B) is preferably 0.3 or less, more preferably 0.2 or less, even more preferably 0.17 or less, and particularly preferably 0.1 or less. Among these, from the viewpoints of solidification of the water-in-oil cosmetic and the stability over time of the water-in-oil cosmetic and the vesicle composition, (a1) / (B) is preferably 0.01 to 0.3, more preferably 0.02 to 0.2, even more preferably 0.022 to 0.17, and particularly preferably 0.022 to 0.1.

[0040] (Component (b1) Wax) Wax is a lipophilic fatty compound with a low melting temperature between room temperature and around 100°C. Taking advantage of this property, wax is mixed with an oil by heating it to its melting point, forming a microscopically homogeneous mixture. When the mixture is returned to room temperature, the wax recrystallizes, forming a house-of-card structure in which plate-like molecular crystals physically interlock with each other, resulting in gelation. Examples of component (b1) wax used in the present technology include hydrocarbon waxes (synthetic waxes) such as polyethylene wax, ethylene propylene copolymer, paraffin wax, Fischer-Tropsch wax, microcrystalline wax, paraffin wax, ceresin wax, and ozokerite; and natural waxes such as rice bran wax, carnauba wax, beeswax, lanolin wax, and candelilla. These may be used alone or in combination as needed.

[0041] Among these, from the viewpoints of the solidification, occlusive properties, and usability of the solid water-in-oil cosmetic according to the present technology, hydrocarbon waxes are preferred, it is more preferred to include two or more hydrocarbon waxes, and it is even more preferred to include one or more waxes selected from paraffin, microcrystalline wax, and rice bran wax.

[0042] The mass content of component (b1) relative to the total mass of the solid water-in-oil cosmetic is not particularly limited and can be freely set as long as it does not impair the action and effect of the present technology. The lower limit of the mass content of component (b1) relative to the total mass of the solid water-in-oil cosmetic is preferably 1 mass% or more, more preferably 2 mass% or more, and even more preferably 4 mass% or more. The upper limit of the mass content of component (b1) relative to the total mass of the solid water-in-oil cosmetic is preferably 30 mass% or less, more preferably 20 mass% or less, and even more preferably 15 mass% or less. Among these, from the viewpoints of solidification of the water-in-oil cosmetic and the stability over time of the water-in-oil cosmetic and the vesicle composition, the mass content of component (b1) relative to the total mass of the solid water-in-oil cosmetic is, for example, preferably 1 to 30 mass%, more preferably 2 to 20 mass%, even more preferably 4 to 20 mass%, and particularly preferably 4 to 15 mass%.

[0043] When a liposome composition is contained as the vesicle composition of the solid water-in-oil cosmetic according to the present technology, the mass ratio (a1) / (b1) of component (a1) to component (b1) is not particularly limited and can be freely set as long as it does not impair the action and effect of the present technology. The lower limit of (a1) / (b1) is preferably 0.005 or more, more preferably 0.01 or more, and even more preferably 0.02 or more. The upper limit of (a1) / (b1) is preferably 0.5 or less, more preferably 0.25 or less, and even more preferably 0.2 or less. Among these, from the viewpoints of solidification of the water-in-oil cosmetic and the stability over time of the water-in-oil cosmetic and the vesicle composition, (a1) / (b1) is preferably 0.005 to 0.5, more preferably 0.01 to 0.25, and even more preferably 0.02 to 0.2.

[0044] (Component (b2) Oil-based gelling agents other than wax) In oil-based gelling agents, molecules dispersed in an oil agent form a three-dimensionally overlapping network structure or aggregates due to physical interactions between molecules such as hydrogen bonds or van der Waals forces, and gel by incorporating the oil agent. The component (b2) gelling agent other than wax used in the present technology is not particularly limited as long as it is one used in ordinary cosmetics, topical skin preparations, etc., and examples include inorganic powders, sugar fatty acid esters, metal soaps, organically modified clay minerals, amino acid gelling agents, glycerin oligoesters, 12-hydroxystearic acid, etc., and one or more of the above components can be selected and used as necessary. Among these, from the viewpoint of the stability over time and the feel when used of the solid water-in-oil cosmetic and the vesicle composition, it is preferable to use at least one selected from the group consisting of dextrin fatty acid esters, sucrose fatty acid esters, inulin fatty acid esters, 12-hydroxystearic acid, metal soaps, organically modified clay minerals, amino acid-based gelling agents, and inorganic powders; it is more preferable to use at least one selected from the group consisting of dextrin fatty acid esters, sucrose fatty acid esters, inulin fatty acid esters, 12-hydroxystearic acid, organically modified clay minerals, and inorganic powders; it is even more preferable to use at least one selected from the group consisting of dextrin fatty acid esters, organically modified clay minerals, and inorganic powders; it is even more preferable to use an inorganic powder such as silica, and hydrophobically treated inorganic powders are particularly preferable.

[0045] As the inorganic powder used in the present technology, silica is preferably used from the viewpoints of the solidification of water-in-oil cosmetics, the stability over time of the vesicle composition, occlusiveness, and usability. Silica is a fine particle of high-purity silicon dioxide. By using silica, the solidification of water-in-oil cosmetics can be more stably maintained and an excellent usability can be imparted. The silica used in the present technology can be any shape, such as spherical or irregular, and regardless of the presence or absence of pores or surface treatment, as long as it can achieve the desired effect. Among them, from the viewpoints of the solidification of water-in-oil cosmetics, occlusiveness, and usability, fumed silica, which has a specific surface area of ​​100 m, is preferred. ２ / g or more and is preferably non-porous.

[0046] The inorganic powder used in the present technology may be a hydrophobically treated inorganic powder, and hydrophobically treated silica (hydrophobically treated silica) is preferred from the viewpoints of the solidification, occlusive properties, and usability of water-in-oil cosmetics. Hydrophobically treated silica is hydrophobized by substituting a portion of the hydrophilic groups covering the silica surface with dimethylcyclosilane groups, trimethylsilane groups, or the like. The use of hydrophobically treated silica improves dispersibility in various oils. Examples of hydrophobizing methods include dimethylsilylation treatment with dimethyldichlorosilane, trimethylsilylation treatment with trimethylchlorosilane or hexamethyldisilazane, octylsilylation treatment with octyltrichlorosilane, silicone treatment with dimethylpolysiloxane or methylhydrogenpolysiloxane, and coating treatment with a metal soap compound. In the present technology, dimethylsilylated silica is particularly preferred as the hydrophobically treated silica. As the hydrophobic treated silica, commercially available products may be used, and examples of commercially available products include AEROSIL 380S (manufactured by Nippon Aerosil Co., Ltd., average particle size: 5 to 7 nm), AEROSIL 200 (manufactured by Nippon Aerosil Co., Ltd., average particle size: 10 to 15 nm), AEROSIL LR972 (manufactured by Nippon Aerosil Co., Ltd., average particle size: 16 nm), and AEROSIL LR976S (manufactured by Nippon Aerosil Co., Ltd., average particle size: 5 to 10 nm).

[0047] Examples of sugar fatty acid esters used in the present technology include dextrin fatty acid esters such as dextrin octanoate, dextrin laurate, dextrin myristate, dextrin palmitate, dextrin palmitate / 2-ethylhexanoate, dextrin stearate, dextrin palmitate / stearate, dextrin oleate, dextrin behenate, and coconut oil fatty acid dextrin; sucrose fatty acid esters such as sucrose stearate (sucrose stearate) and sucrose palmitate; fructooligosaccharide fatty acid esters such as fructooligosaccharide stearate; and inulin fatty acid esters such as inulin stearate. Commercially available sugar fatty acid esters may be used, and examples of commercially available products include dextrin fatty acid esters such as Leopearl (registered trademark) KL2 (dextrin palmitate), Leopearl TT2 (dextrin (palmitate / ethylhexanoate)), and Leopearl MKL2 (dextrin myristate), manufactured by Chiba Flour Milling Co., Ltd.; and Leopearl ISK2 (inulin stearate).

[0048] Examples of the metal soap used in the present technology include aluminum stearate, magnesium stearate, calcium stearate, calcium palmitate, lithium 2-ethylhexanoate, and aluminum 12-hydroxystearate.

[0049] Examples of organically modified clay minerals used in the present technology include those in which the convertible cations present between the crystal layers of clay minerals such as montmorillonite, saponite, hectorite, and bentonite have been substituted with organic polar compounds or organic cations. Specific examples include dimethyldistearylammonium hectorite, dimethyldistearylammonium bentonite, benzyldimethyldistearylammonium hectorite, disteardimonium hectorite, dioctadecyldimethylammonium salt-modified montmorillonite, octadecyldimethylbenzylammonium salt-modified montmorillonite, and dihexadecyldimethylammonium salt-modified montmorillonite.

[0050] Examples of amino acid gelling agents used in the present technology include lauroyl glutamic acid stearylamide, N-lauroyl-L-glutamic acid dibutylamide, N-2-ethylhexanoyl-L-glutamic acid dibutylamide, dicaproyl lysine laurylamine salt, dicaproyl lysine lauryl ester, dicaproyl lysine lauroyl phenylalanine laurylamide, and the like.

[0051] Examples of glycerin oligoesters used in the present technology include glycerin-based oligoester gelling agents synthesized from glycerin, eicosanedioic acid, and behenic acid (referred to as glyceryl (behenic acid / eicosanedioic acid); the same applies to the glycerin-based oligoester gelling agents hereinafter), glyceryl laurate 2-ethyloctadecanedioate, glyceryl myristate tetradecanedioate, glyceryl palmitate eicosanedioate, glyceryl stearate hexadecanedioate, glyceryl isostearate eicosanedioate, glyceryl behenate octadecanedioate, glyceryl 2-ethylhexanoate dodecanedioate, and glyceryl oleate 2-ethyloctadecanedioate.

[0052] The mass content of component (b2) relative to the total mass of the solid water-in-oil cosmetic is not particularly limited and can be freely set as long as it does not impair the action and effect of the present technology. The lower limit of the mass content of component (b2) relative to the total mass of the solid water-in-oil cosmetic is preferably 0.1 mass% or more, more preferably 0.3 mass% or more, and even more preferably 0.5 mass% or more. The upper limit of the mass content of component (b2) relative to the total mass of the solid water-in-oil cosmetic is preferably 10 mass% or less, more preferably 5 mass% or less, even more preferably 3 mass% or less, and particularly preferably 2 mass% or less. Among these, from the viewpoints of solidification of the water-in-oil cosmetic and the stability over time of the water-in-oil cosmetic and the vesicle composition, the mass content of component (b2) relative to the total mass of the solid water-in-oil cosmetic is, for example, preferably 0.1 to 10 mass%, more preferably 0.3 to 5 mass%, even more preferably 0.5 to 3 mass%, and particularly preferably 0.5 to 2 mass%.

[0053] When a liposome composition is contained as the vesicle composition of the solid water-in-oil cosmetic according to the present technology, the mass ratio (a1) / (b2) of component (a1) to component (b2) is not particularly limited and can be freely set as long as it does not impair the action and effect of the present technology. The lower limit of (a1) / (b2) is preferably 0.01 or more, more preferably 0.05 or more, and even more preferably 0.1 or more. The upper limit of (a1) / (b2) is preferably 3 or less, more preferably 2 or less, and even more preferably 1 or less. Among these, from the viewpoints of solidification of the water-in-oil cosmetic and the stability over time of the water-in-oil cosmetic and the liposome composition, (a1) / (b2) is preferably 0.01 to 3, more preferably 0.05 to 2, and even more preferably 0.1 to 1.

[0054] When component (B) contains component (b1) wax and component (b2) an oil-based gelling agent other than wax, the content mass ratio of component (b1) to component (b2), (b1) / (b2), is not particularly limited and can be freely set as long as it does not impair the action and effect of the present technology. The lower limit of (b1) / (b2) is preferably 1 or more, more preferably 2 or more. The upper limit of (b1) / (b2) is preferably 40 or less, more preferably 20 or less, and even more preferably 15 or less. Among these, from the viewpoints of solidification of the water-in-oil cosmetic and the stability over time of the water-in-oil cosmetic and the vesicle composition, (b1) / (b2) is preferably 1 to 40, more preferably 2 to 20, and even more preferably 2 to 15.

[0055] [Component (C) Lipophilic Surfactant] The lipophilic surfactant component (C) used in the present technology contributes to the dispersion stability and emulsification stability of the vesicle composition dispersion (aqueous phase) in the oil phase, and can also significantly improve its stability over time. The lipophilic surfactant component (C) used in the present technology is not particularly limited as long as it is one that is used in ordinary cosmetics, topical skin preparations, etc., but from the viewpoints of the dispersion stability and emulsification stability of the vesicle composition dispersion (aqueous phase) in the oil phase, and ultimately the stability over time of the solid water-in-oil cosmetic and vesicle composition, it is preferably a lipophilic surfactant with an HLB of 2 to 7, and more preferably a lipophilic surfactant with an HLB of 2 to 6.

[0056] Examples of lipophilic surfactants having an HLB of 2 to 7 used in the present technology include diglyceryl monostearate, diglyceryl monooleate, diglyceryl dioleate, diglyceryl monoisostearate, tetraglyceryl monostearate, tetraglyceryl monooleate, hexaglyceryl tristearate, decaglyceryl trioleate, decaglyceryl pentastearate, decaglyceryl pentaoleate, decaglyceryl pentaisostearate, sorbitan monopalmitate, sorbitan monostearate, sorbitan sesquistearate, sorbitan tristearate, and sorbitan monooleate. , sorbitan sesquioleate, sorbitan trioleate, sorbitan monoisostearate, sorbitan sesquiisostearate, polyoxyethylene (3) castor oil, polyoxyethylene (10) castor oil, polyoxyethylene (5) hydrogenated castor oil, polyoxyethylene (10) hydrogenated castor oil, polyethylene glycol monostearate (1 E.O.), polyethylene glycol monostearate (2 E.O.), polyethylene glycol monostearate (4 E.O.), polyethylene glycol monooleate (2 E.O.), ethylene glycol monostearate, diethylene glycol stearate Examples of such copolymers include polyoxyethylene-methylpolysiloxane copolymers, methylpolysiloxane-cetylmethylpolysiloxane-poly(oxyethylene-oxypropylene)methylpolysiloxane copolymers, poly(oxyethylene-oxypropylene)methylpolysiloxane copolymers, PEG-9 polydimethylsiloxyethyl dimethicone, polyoxyethylenemethylsiloxane-polyoxypropyleneoleylmethylsiloxane-dimethylsiloxane copolymers, etc. These may be used alone or in combination as needed.

[0057] Among these, silicone surfactants are preferred from the viewpoints of dispersion stability and emulsion stability of the vesicle composition dispersion (aqueous phase) in the oil phase, and ultimately, the stability over time of the solid water-in-oil cosmetic and the vesicle composition. The silicone surfactant may be a graft copolymer having an organopolysiloxane group as the main chain and hydrophilic groups on the side chains, or it may contain a linear block copolymer or a crosslinked polymer in which organopolysiloxane groups and hydrophilic groups are alternately bonded. Specific examples of surfactants having a linear organopolysiloxane group as the main chain and polyoxyalkylene groups on the side chains include polyoxyalkylene-modified organopolysiloxanes and polyoxyalkylene / alkyl-co-modified organopolysiloxanes, and those having hydrophilic groups include polyether-modified silicones having polyether chains and polyglycerin-modified silicones having polyglycerin chains.

[0058] More specifically, polyglycerin fatty acid esters such as diglyceryl monostearate (HLB 5.0), diglyceryl monooleate (HLB 6.5), diglyceryl dioleate (HLB 7.0), diglyceryl monoisostearate (HLB 5.5), tetraglyceryl monostearate (HLB 6.0), tetraglyceryl monooleate (HLB 6.0), and hexaglyceryl tristearate (HLB 2.5) are preferred. sorbitan fatty acid esters such as sorbitan monostearate (HLB 4.7), sorbitan sesquistearate (HLB 4.2), sorbitan sesquiisostearate (HLB 4.0), and sorbitan sesquioleate (HLB 3.7), polyoxyethylene-methylpolysiloxane copolymers (for example, cosmetic ingredient name: PEG-10 dimethicone (HLB 4.5)), methylpolysiloxane-cetylmethyl Examples of the surfactant include polyether-modified silicones such as polysiloxane-poly(oxyethylene-oxypropylene)methylpolysiloxane copolymer (HLB 5.0), poly(oxyethylene-oxypropylene)methylpolysiloxane copolymer (Cosmetic All Ingredients Name: PEG / PPG-20 / 22 butyl ether dimethicone) (HLB 7.0), PEG-9 polydimethylsiloxyethyl dimethicone (HLB 4.0), and lauryl PEG-9 polydimethylsiloxyethyl dimethicone (HLB 3.0), polyglycerin-modified silicones such as lauryl polyglyceryl-3 polydimethylsiloxyethyl dimethicone (HLB 3.0), and block copolymer-type silicone surfactants such as poly(oxyethylene-oxypropylene)-butylene-methylpolysiloxane copolymer (HLB 6.0), and these surfactants may be used alone or in combination. Among these, polyether-modified silicones and / or polyglycerin-modified silicones having polyoxyethylene groups are more preferred, and as the polyether-modified silicone, PEG-9 polydimethylsiloxyethyl dimethicone is even more preferred, and as the polyglycerin-modified silicone, lauryl polyglyceryl-3 polydimethylsiloxyethyl dimethicone is even more preferred.

[0059] The mass content of component (C) relative to the total mass of the solid water-in-oil cosmetic is not particularly limited and can be freely set as long as it does not impair the action and effect of the present technology. The lower limit of the mass content of component (C) relative to the total mass of the solid water-in-oil cosmetic is preferably 0.5 mass% or more, more preferably 1 mass% or more, and even more preferably 2 mass% or more. The upper limit of the mass content of component (C) relative to the total mass of the solid water-in-oil cosmetic is preferably 10 mass% or less, more preferably 8 mass% or less, even more preferably 7 mass% or less, and even more preferably 6 mass% or less. Among these, from the viewpoints of dispersion stability and emulsion stability of the vesicle composition dispersion (aqueous phase) in the oil phase, and in turn, the stability over time of the solid water-in-oil cosmetic and the vesicle composition, the content by mass of component (C) relative to the total mass of the solid water-in-oil cosmetic is, for example, preferably 0.5 to 10 mass%, more preferably 1 to 8 mass%, even more preferably 2 to 7 mass%, and even more preferably 2 to 6 mass%.

[0060] When a liposome composition is contained as the vesicle composition of the solid water-in-oil cosmetic according to the present technology, the mass ratio (a1) / (C) of component (a1) to component (C) is not particularly limited and can be freely set as long as it does not impair the action and effect of the present technology. The lower limit of (a1) / (C) is preferably 0.005 or more, more preferably 0.01 or more, even more preferably 0.05 or more, still more preferably 0.07 or more, and particularly preferably 0.1 or more. The upper limit of (a1) / (C) is preferably 1 or less, more preferably 0.5 or less, even more preferably 0.4 or less, and particularly preferably 0.3 or less. Among these, from the viewpoints of the dispersion stability and emulsion stability of the vesicle composition dispersion (aqueous phase) in the oil phase, and in turn the stability over time of the solid water-in-oil cosmetic and the vesicle composition, (a1) / (C) is, for example, preferably 0.005 to 1, more preferably 0.01 to 0.5, even more preferably 0.05 to 0.4, still more preferably 0.07 to 0.3, and particularly preferably 0.1 to 0.3.

[0061] [Component (D) Glycerin fatty acid ester] Glycerin fatty acid ester is an ester of a fatty acid and glycerin. Note that the component (D) glycerin fatty acid ester of the present technology does not contain the component (C) lipophilic surfactant. The component (D) glycerin fatty acid ester used in the present technology can further improve the dispersion stability and emulsion stability of the vesicle composition dispersion (aqueous phase) in the oil phase, and ultimately the stability over time of the solid water-in-oil cosmetic and the vesicle composition. The glycerin fatty acid ester of component (D) used in the present technology is not particularly limited as long as it is one that is used in ordinary cosmetics, topical skin preparations, and the like, and examples thereof include polyglycerin fatty acid esters such as polyglyceryl-2 triisostearate, polyglyceryl-2 diisostearate, polyglyceryl-10 stearate, polyglyceryl-10 diisostearate, polyglyceryl-10 tristearate, polyglyceryl-6 isostearate, polyglyceryl-5 trioleate, polyglyceryl-10 laurate, polyglyceryl-2 isostearate, and polyglyceryl-2 diisostearate.

[0062] From the viewpoints of dispersion stability and emulsion stability of the vesicle composition dispersion (aqueous phase) in the oil phase, and in turn, the stability over time of the solid water-in-oil cosmetic and the vesicle composition, component (D) is preferably a glycerin fatty acid ester having one or two hydroxyl groups in the molecule, more preferably polyglyceryl-2 triisostearate or polyglycerin-2 diisostearate, and even more preferably polyglyceryl-2 triisostearate and polyglycerin-2 diisostearate.

[0063] The mass content of component (D) relative to the total mass of the solid water-in-oil cosmetic is not particularly limited and can be freely set as long as it does not impair the action and effect of the present technology. The lower limit of the mass content of component (D) relative to the total mass of the solid water-in-oil cosmetic is preferably 1 mass% or more, more preferably 5 mass% or more, and even more preferably 8 mass% or more. The upper limit of the mass content of component (D) relative to the total mass of the solid water-in-oil cosmetic is preferably 30 mass% or less, more preferably 20 mass% or less, even more preferably 15 mass% or less, and particularly preferably 12 mass% or less. Among these, from the viewpoints of dispersion stability and emulsion stability of the vesicle composition dispersion (aqueous phase) in the oil phase, and in turn, the stability over time of the solid water-in-oil cosmetic and the vesicle composition, the content by mass of component (D) relative to the total mass of the solid water-in-oil cosmetic is, for example, preferably 1 to 30 mass%, more preferably 5 to 20 mass%, even more preferably 5 to 15 mass%, and particularly preferably 8 to 12 mass%.

[0064] When a liposome composition is contained as the vesicle composition of the solid water-in-oil cosmetic according to the present technology, the mass ratio (a1) / (D) of component (a1) to component (D) is not particularly limited and can be freely set as long as it does not impair the action and effect of the present technology. The lower limit of (a1) / (D) is preferably 0.0005 or more, more preferably 0.001 or more, even more preferably 0.005 or more, and particularly preferably 0.01 or more. The upper limit of (a1) / (D) is preferably 0.5 or less, more preferably 0.2 or less, even more preferably 0.1 or less, and particularly preferably 0.05 or less. Among these, from the viewpoints of dispersion stability and emulsion stability of the vesicle composition dispersion (aqueous phase) in the oil phase, and in turn, the stability over time of the solid water-in-oil cosmetic and the vesicle composition, (a1) / (D) is, for example, preferably 0.0005 to 0.5, more preferably 0.001 to 0.2, even more preferably 0.005 to 0.1, and particularly preferably 0.01 to 0.05.

[0065] <Oil-Based Component> The solid water-in-oil cosmetic according to the present technology contains the oily components (B) and (C), and components forming the oil phase can be those used in ordinary cosmetics, topical skin preparations, etc., as long as they do not impair the effects of the present technology. The oil agent according to the present technology can be used regardless of its nature (liquid, paste, solid, etc.), volatile / non-volatile, animal oil, vegetable oil, synthetic oil, etc., and examples of oil agents that can be used include hydrocarbon oils, ester oils, fatty oils, higher alcohols, silicone oils, fluorinated oils, and lanolin derivatives. Among these, from the viewpoint of dispersibility of the oily component, liquid oils are particularly preferred, ester oils and / or hydrocarbon oils are more preferred, and ester oils and hydrocarbon oils are even more preferred. When ester oils and hydrocarbon oils are used, from the viewpoints of solidification, occlusive properties, and usability of the solid water-in-oil cosmetic, the blending ratio (ester oil / hydrocarbon oil) is preferably greater than 1, more preferably 1.1 or more, and even more preferably 1.2 or more. The upper limit is not particularly limited, but the blending ratio (ester oil / hydrocarbon oil) is preferably 3 or less, and more preferably 2.5 or less. The mass content of the liquid oil relative to the total mass of the solid water-in-oil cosmetic is not particularly limited and can be freely set as long as it does not impair the action and effect of the present technology. The lower limit of the mass content of the liquid oil relative to the total mass of the solid water-in-oil cosmetic is preferably 20% by mass or more, more preferably 30% by mass or more, and even more preferably 50% by mass or more. The upper limit of the mass content of the liquid oil relative to the total mass of the solid water-in-oil cosmetic is preferably 85% by mass or less, more preferably 80% by mass or less, and even more preferably 70% by mass or less. Among these, from the viewpoints of the stability over time of the vesicle composition, the solidification of the water-in-oil cosmetic, occlusive properties, and the feel when used, the content by mass of the liquid oil relative to the total mass of the solid water-in-oil cosmetic is, for example, preferably 20 to 85% by mass, more preferably 30 to 80% by mass, and even more preferably 50 to 70% by mass.

[0066] (Hydrocarbon Oil) Examples of hydrocarbon oils used in the present technology include liquid paraffin, heavy liquid isoparaffin, squalane, polyisobutylene, polybutene, etc. From the viewpoint of the solidification, occlusive properties, and usability of the solid water-in-oil cosmetic, it is preferable that the hydrocarbon oil has at least a specific viscosity. Specifically, the kinematic viscosity at 98.9°C is 100 mm or less as the lower limit. ２ / s or more, and 200 mm ２ / s or more is more preferable. ２ / s or less, and ２ / s or less, and more preferably 1,000 mm ２ / s or less, and more preferably 500 mm ２ The hydrocarbon oil of the present technology may be a commercially available product, and an example of a commercially available product is Parleam 18 (average carbon number: 72 / average molecular weight: 1,000 / kinematic viscosity at 98.9°C: 290 mm ２ / s), Parleam 24 (average carbon number 96 / average molecular weight: 1,350 / 98.9 °C kinematic viscosity 740 mm ２ / s), Parleam 46 (average carbon number 184 / average molecular weight: 2,650 / 98.9 °C kinematic viscosity 5,000 mm ２ / s) (all manufactured by NOF Corporation).

[0067] The blending ratio of the hydrocarbon oil to the component (B) oily gelling agent used in the present technology (hydrocarbon oil / component (B) oily gelling agent) is not particularly limited and can be freely set as long as it does not impair the action and effect of the present technology. The lower limit of (hydrocarbon oil / component (B) oily gelling agent) is preferably 1 or more, more preferably 1.5 or more, and even more preferably 2 or more. The upper limit of (hydrocarbon oil / component (B) oily gelling agent) is preferably 10 or less, more preferably 8 or less, and even more preferably 5 or less. Among these, from the viewpoints of the solidification, occlusive property, and usability of the solid water-in-oil cosmetic, for example, the (hydrocarbon oil / component (B) oily gelling agent) is preferably 1 to 10, more preferably 1.5 to 8, and even more preferably 2 to 5.

[0068] The blending ratio (hydrocarbon oil / component (b1) wax) of the hydrocarbon oil and component (b1) wax used in the present technology is not particularly limited, and can be freely set as long as it does not impair the action and effect of the present technology. The lower limit of (hydrocarbon oil / component (b1) wax) is preferably 1 or more, more preferably 2 or more. The upper limit of (carbonized (hydrocarbon oil / component (b1) wax)) is preferably 15 or less, more preferably 10 or less, and even more preferably 8 or less. Among these, from the viewpoints of the solidification, occlusive property, and usability of the solid water-in-oil cosmetic, for example, (hydrocarbon oil / component (b1) wax) is preferably 1 to 15, more preferably 1 to 10, and even more preferably 2 to 8.

[0069] (Ester Oil) Examples of ester oils used in the present technology include diisostearyl malate, isopropyl myristate, isopropyl palmitate, triethylhexanoin, octyldodecyl myristate, propylene glycol dicaprate, cetyl 2-ethylhexanoate, 2-ethylhexyl hydroxystearate, pentaerythrityl tetraisostearate, octyldodecyl stearoyloxystearate, and 2-ethylhexyl paramethoxycinnamate. Furthermore, from the viewpoints of occlusive properties and usability, it is preferable to contain an ester oil having at least a specific viscosity or an ester oil having a molecular weight of 500 or more. Specifically, it is preferable for the viscosity at 30°C to be 1,000 mPa·s or more, and it is more preferable to contain an ester oil having a molecular weight of 600 or more. While there are no particular limitations on the ester oil as long as it satisfies these viscosity and molecular weight requirements, examples include diisostearyl malate. From the viewpoints of occlusive property, feeling during use, and the like, the content by mass of the ester oil having a specific viscosity or the ester oil having a molecular weight of 500 or more relative to the total mass of the ester oils used in the present technology is preferably 30 to 80 mass%, more preferably 30 to 70 mass%, and even more preferably 40 to 70 mass%.

[0070] <Other Components> In addition to the above-mentioned components (A) to (D), the solid water-in-oil cosmetic composition according to the present technology may contain components that are typically contained in cosmetics, such as powders, surfactants, aqueous components, oily components, moisturizers, antioxidants, cosmetic ingredients, preservatives, colorants, and fragrances, to the extent that the effects of the present technology are not impaired.

[0071] The aqueous component according to the present technology may be water or a liquid component compatible with water, as long as it can be contained in cosmetics, quasi-drugs, pharmaceuticals, etc. Examples of water include purified water, hot spring water, deep sea water, tap water, distilled water, ion-exchanged water, and steam-distilled water from plants. Examples of water-soluble liquid components include lower alcohols such as ethanol, and alkylene oxide derivatives such as polyoxyethylene methyl glucoside, polyoxypropylene methyl glucoside, and polyoxypropylene diglyceryl ether. One or more of these may be used as needed. The upper limit of the water content according to the present technology is preferably 80% by mass or less, more preferably 70% by mass, even more preferably 60% by mass, and even more preferably 50% by mass or less. From the viewpoint of occlusiveness, etc., it is more preferably 40% by mass or less, even more preferably 30% by mass or less, even more preferably 20% by mass or less, and particularly preferably 15% by mass or less. Furthermore, the lower limit may be 0% by mass, and from the viewpoint of the stability over time of the solid water-in-oil cosmetic and the vesicle composition, the lower limit is preferably 0.1% by mass or more, more preferably 0.5% by mass or more, even more preferably 1% by mass or more, and particularly preferably 3% by mass or more.

[0072] The hardness of the solid water-in-oil cosmetic according to the present technology is not particularly limited. However, from the viewpoint of maintaining good stability over time of the solid water-in-oil cosmetic while favorably exhibiting usability such as ease of removal and good spreadability upon application, the lower limit of the penetration load (gf) is preferably 50 gf (gram force) or more, more preferably 100 gf or more, and the upper limit of the penetration load (gf) is preferably 500 gf or less, more preferably 300 gf or less. Among these, for example, a range of 50 to 500 gf is preferred, and a range of 100 to 300 gf is preferable. When the penetration load (gf) is within such a numerical range, the effects of the present technology are exhibited and a solid water-in-oil cosmetic having even better usability such as ease of removal and good spreadability upon application can be obtained. In the present technology, the penetration load was measured using a rheometer manufactured by Rheotec Corporation. Specifically, the measurement was carried out at a measurement temperature of 35° C., a range of 500 gf, and by using a 10 mmφ disc adapter and penetrating it 2 mm at a speed of 6 cm / min.

[0073] The solid water-in-oil cosmetic composition according to the present technology is not particularly limited in its use and can be used in ordinary cosmetics. Among these, it is preferable that it be applied to skin care cosmetics and lip cosmetics (e.g., lip balm, lipstick, lip gloss, etc.), where the effects of the present technology are expected to be even more pronounced. Furthermore, its use can be achieved by direct application or application on the hands or fingers, etc.

[0074] The solid water-in-oil cosmetic composition of the present technology can be produced by a commonly known method, and any production equipment may be used as long as it is a dispersing / emulsifying equipment such as a general dispersion equipment. For example, the cosmetic composition can be obtained by heating and mixing components (B) to (D), adding preheated component (A) thereto, mixing uniformly, and then cooling.

[0075] The present technology can also employ the following configurations. [1] A solid water-in-oil cosmetic containing at least component (A) a vesicle composition, component (B) an oily gelling agent, and component (C) a lipophilic surfactant. [2] The solid water-in-oil cosmetic according to [1], wherein component (A) is a liposome composition. [3] The solid water-in-oil cosmetic according to [2], wherein component (A) is a liposome composition containing at least component (a1) a phospholipid, component (a2) a sterol, and component (a3) ​​a polyhydric alcohol. [4] The solid water-in-oil cosmetic according to any one of [1] to [3], wherein component (B) contains at least component (b1) a wax. [5] The solid water-in-oil cosmetic according to any one of [1] to [4], wherein the content of component (b1) is 1 to 30% by mass based on the total amount of the cosmetic. [6] The solid water-in-oil cosmetic according to any one of [1] to [5], wherein the component (B) contains component (b1) a wax and component (b2) an oil-based gelling agent other than a wax. [7] The solid water-in-oil cosmetic according to [6], wherein the component (b2) is at least one selected from the group consisting of dextrin fatty acid esters, sucrose fatty acid esters, inulin fatty acid esters, 12-hydroxystearic acid, metal soaps, organically modified clay minerals, amino acid-based gelling agents, and inorganic powders. [8] The solid water-in-oil cosmetic according to [7], wherein the component (b2) is an inorganic powder. [9] The solid water-in-oil cosmetic according to any one of [1] to [8], further containing component (D) a glycerin fatty acid ester (excluding component (C)).

[10] The solid water-in-oil cosmetic according to [9], wherein the component (D) is a glycerin fatty acid ester having one or two hydroxyl groups in the molecule.

[11] The solid water-in-oil cosmetic according to [9] or

[10] , wherein the component (D) is at least one selected from polyglyceryl-2 triisostearate and polyglycerin-2 diisostearate.

[12] The solid water-in-oil cosmetic according to any one of [1] to

[11] , wherein the component (C) is a silicone surfactant.

[13] A solid water-in-oil cosmetic according to any one of [1] to

[12] , wherein the water content is 80% by mass or less, based on the total amount of the cosmetic.

[14] A solid water-in-oil cosmetic according to any one of [1] to

[13] , wherein the water content is 50% by mass or less, based on the total amount of the cosmetic.

[15] A solid water-in-oil cosmetic according to any one of [1] to

[14] , wherein the cosmetic has a penetration load value of 50 to 500 gf.

[16] A solid water-in-oil cosmetic according to any one of [1] to

[15] , wherein the cosmetic is a skin care cosmetic.

[17] A solid water-in-oil cosmetic according to any one of [1] to

[16] , wherein the cosmetic is a lip cosmetic.

[0076] The present technology will be described in more detail below with reference to examples, which are not intended to limit the present technology in any way.

[0077] Examples 1 to 11, Comparative Example 1: Solid Water-in-Oil Cosmetics (Lip Cosmetics) The solid water-in-oil cosmetics (lip cosmetics) of the Examples and Comparative Examples were prepared using the compositions shown in Table 1 and the methods described below. The obtained solid water-in-oil cosmetics (lip cosmetics) were evaluated and judged using the following evaluation methods and criteria for "A. Penetration load value (of solid water-in-oil cosmetics)," "B. Stability immediately after production (of solid water-in-oil cosmetics)," "C. Stability over time (50°C / 1M) (of solid water-in-oil cosmetics)," and "D. Vesicle (liposome) stability." The results are shown in Table 1. The obtained solid water-in-oil cosmetics (lip cosmetics) were also evaluated and judged using the following evaluation methods and criteria for "E. Occlusive property, F. Removal feel, G. Ease of spread upon application." The results are shown in Table 2. In Tables 1 and 2 and Examples 12 to 18 outside the tables, hydrogenated soybean phospholipids with a PC purity of 80 to 90% were used.

[0078] Note 1: Phytosterol QI (Mitsubishi Chemical Foods) Note 2: Kairei Marine Cholesterol (Nippon Suisan) Note 3: Synthetic Ceresin JNP-81 (Nippon Natural Products) Note 4: MULTIWAX W445 (SONNEBORN. LLC) Note 5: Rice Wax SS-1 (Bosso Oil & Fats) Note 6: AEROSIL LR972 (smoke, non-porous, specific surface area: 110 m ２ / g specific surface area, manufactured by Nippon Aerosol Co., Ltd.) Note 7: KF-6105 (manufactured by Shin-Etsu Chemical Co., Ltd.) Note 8: KF-6028P (manufactured by Shin-Etsu Chemical Co., Ltd.) Note 9: Cosmol 43V (manufactured by Nisshin Oillio Group, Ltd.) Note 10: Pearleem 18 (manufactured by NOF Corporation) Note 11: CARNATION (manufactured by SONNEBORN, LLC)

[0079]

[0080] [Manufacturing Method] A: Components (1) to (5) are heated to 70°C and mixed uniformly. B: Component (6) is heated to 70°C. C: B is gradually added to A and dispersed using a Desper Mixer. D: C is cooled to room temperature and subjected to high-pressure processing using a microfluidizer to prepare a vesicle (liposome) dispersion. The liposome composition prepared here was confirmed to be a multilamellar vesicle consisting of a multilayer bilayer membrane structure. E: Components (7) to (18) are heated to 85°C and mixed uniformly. F: D, heated to 85°C, is gradually added to E and dispersed uniformly. G: F is filled into a resin jar (40H x 56W x 56L MCW-50, manufactured by Takemoto Container Co., Ltd.) at 80°C and cooled to obtain a solid water-in-oil cosmetic (lip cosmetic).

[0081] [Evaluation Method] A. Penetration Load Value (of Solid Water-in-Oil Cosmetics) The penetration load value was measured using a rheometer (manufactured by Rheotec Corporation) at a measurement temperature of 35°C, a range of 500 gf, and a 10 mmφ disc adapter at a penetration depth of 2 mm at a speed of 6 cm / min. This measurement was carried out three times, and the average value of the three measurements was evaluated according to the following three-level evaluation criteria. <Three-Level Evaluation Criteria> [Evaluation]: [Penetration Load Value] A: 100-300 gf B: Less than 100 gf C: More than 300 gf

[0082] B. Stability immediately after production (of solid water-in-oil cosmetics) Stability immediately after production was evaluated according to the following three-level evaluation criteria. Separation also includes drained liquid. <Three-level evaluation criteria> [Evaluation]: [Evaluation] A (Excellent): No separation at all, very good texture B (Good): Almost no separation, good texture C (Poor): Clear separation, poor texture

[0083] C. Stability over time (of solid water-in-oil cosmetics) (50°C / 1M) For stability over time, each sample was stored at a constant temperature of 50°C for one month, and then compared with samples immediately after production in terms of the state of separation, and evaluated according to the following four-level evaluation criteria. Note that separation also includes drained liquid. <Four-level evaluation criteria> [Evaluation]: [Evaluation] A (Excellent): No separation at all, very good texture B (Good): Almost no separation, good texture C (Acceptable): Slight separation, but good texture D (Failure): Clear separation, poor texture

[0084] D. Vesicle (liposome) Stability The average particle size of each sample was measured after one month of storage at room temperature and at a constant temperature of 40°C. The retention of the vesicle (liposome) composition was evaluated based on the rate of change in the average particle size relative to the value immediately after production, and the stability of the vesicle (liposome) composition was assessed using the following four-level evaluation criteria. (Method for Measuring Average Particle Size) 10 g of each sample was dissolved by heating at 80°C, and then 90 g of 80°C water was added and mixed for 5 minutes to extract the vesicle (liposome) composition into the aqueous phase. The extract was filled into a plastic cuvette UVette 220-1600 nm (manufactured by Eppendorf), and the peak particle size of the vesicles (liposomes) was measured using a real-time nanoparticle size measurement device, DelsaMaxCORE (manufactured by Beckman Coulter, Inc.). Each sample was measured three times, and the average of the three measurements was recorded as the "average particle size." <4-level evaluation criteria> [Evaluation]: [Evaluation criteria] A (Excellent): The rate of change in average particle size is less than ±20% B (Good): The rate of change in average particle size is between ±20% and ±40% C (Fail): The rate of change in average particle size is more than ±40%

[0085] E. Occlusion, F. Removal Feeling, G. Ease of Spreading Upon Application For occlusion, removal feel, and ease of spreadability upon application, each sample was used by 10 expert cosmetic evaluation panel members, who evaluated and scored them according to the following evaluation criteria. The average score for each sample was calculated from the total scores of all panel members, and the results were judged according to the following four-level evaluation criteria. For occlusion, each sample was applied to the lips, and the occlusion and seal-in feel after spreading were evaluated. For removal feel, each sample was scooped up with a finger, and the ease of removal and ease of finger spread were evaluated. For spreadability, each sample was applied to the lips, and the ease of uniform spreadability upon spreading was evaluated. <Absolute evaluation criteria> [Score]: [Evaluation] 5 points: Very good 4 points: Good 3 points: Neither good nor bad 2 points: Poor 1 point: Very poor <4-level evaluation criteria> [Judgment]: [Average score] A (Excellent): 4.0 points or more B (Good): 3.5 points or more but less than 4.0 points C (Fair): 2.5 points or more but less than 3.5 points D (Poor): Less than 2.5 points

[0086] As is clear from Table 1 above, all of the solid water-in-oil cosmetics (lip cosmetics) of Examples 1 to 11 obtained favorable results in the evaluation categories of "Stability (of solid water-in-oil cosmetics) immediately after production," "Stability over time (50°C / 1M) (of solid water-in-oil cosmetics)," and "Stability of vesicles (liposomes)." Furthermore, as is clear from Table 2 above, all of the solid water-in-oil cosmetics (lip cosmetics) of Examples 1, 2, and 4 to 10 obtained favorable results in terms of occlusiveness, removal feel, and spreadability upon application. On the other hand, the solid water-in-oil cosmetic (lip cosmetic) of Comparative Example 1, which did not contain component (C), did not provide favorable results in "Stability (of solid water-in-oil cosmetics) immediately after production" or "Stability of vesicles (liposomes)." Regarding "Penetration Load Value," the cosmetic itself was unable to maintain its solid form due to drainage, and therefore could not be evaluated. Furthermore, the "temporal stability (50°C / 1M) (of solid water-in-oil cosmetic preparations)" could not be evaluated because the stability immediately after production was not satisfactory. The solid water-in-oil cosmetic preparation (lip cosmetic preparation) of Comparative Example 1 did not show good results in terms of occlusiveness, and as described above, was unable to maintain its solid state, so it was not possible to evaluate the "removal feel and spreadability upon application."

[0087] Example 12: Solid water-in-oil cosmetic (lip balm) (Ingredients) (% by mass) 1. Hydrogenated soybean phospholipid 0.5 2. Phytosterol Note 1 0.1 3. 1,3-butylene glycol 2 4. Glycerin 2 5. Purified water 10 6. Paraffin Note 3 5 7. Microcrystalline wax Note 4 5 8. Silica dimethyl silylate Note 6 2 9. Lauryl polyglyceryl-3 polydimethylsiloxyethyl dimethicone Note 7 5 10. Polyglyceryl-2 triisostearate Note 9 5 11. Polyglyceryl-2 diisostearate Note 12 5 12. Hydrogenated polyisobutene Note 10 10 13. Mineral oil Note 11 20 14. Diisostearyl malate 10 15. Triethylhexanoin remaining amount 16. Dimethicone (kinematic viscosity 10 mm at 25 ° C) ２ / s) 5 17. Phenoxyethanol 0.5 18. BHT 0.1 19. Tocopherol 0.1 20. Ceramide NG 0.1 21. Ceramide NP 0.1 22. Fragrance 0.1 Note 12: Cosmol 42V (manufactured by Nisshin Oillio Group Co., Ltd.)

[0088] [Manufacturing Method] A: Components (1) to (4) are heated to 70°C and mixed uniformly. B: Component (5) is heated to 70°C. C: B is gradually added to A and dispersed using a Desper Mixer. D: C is cooled to room temperature and subjected to high-pressure processing using a microfluidizer to prepare a liposome dispersion. The liposome composition prepared here was confirmed to be a multilamellar vesicle with a multilayer bilayer membrane structure. E: Components (6) to (22) are heated to 85°C and mixed uniformly. F: D, heated to 85°C, is gradually added to E and dispersed uniformly. G: F is filled into a resin jar (40H x 56W x 56LMCW-50, manufactured by Takemoto Container Co., Ltd.) at 80°C and cooled to obtain a solid water-in-oil cosmetic (lip balm).

[0089] The solid water-in-oil cosmetic (lip balm) of Example 12 was excellent in "stability (of solid water-in-oil cosmetic) immediately after production," "stability (of solid water-in-oil cosmetic) immediately after production," and "vesicle (liposome) stability." Furthermore, good results were obtained in occlusiveness, removal feel, and spreadability upon application. The penetration load value was also rated A.

[0090] Example 13: Solid water-in-oil cosmetic (lipstick) (Ingredients) (% by mass) 1. Hydrogenated soybean phospholipid 0.5 2. Phytosterol Note 1 0.1 3. 1,3-butylene glycol 2 4. Glycerin 2 5. Purified water 10 6. Paraffin Note 3 10 7. Microcrystalline wax Note 4 10 8. Candelilla wax Note 13 1 9. Carnauba wax 1 10. Silica dimethyl silylate Note 6 2 11. Dextrin palmitate Note 14 1 12. Lauryl polyglyceryl-3 polydimethylsiloxyethyl dimethicone Note 7 5 13. Polyglyceryl-2 triisostearate Note 9 5 14. Hydrogenated polyisobutene Note 15 10 15. Isododecane 5 16. Diisostearyl malate 10 17. Triethylhexanoin Remaining amount 18. Dimethicone (kinematic viscosity 100 mm at 25 ° C) ２ / s) 2 19. Diphenyl dimethicone 5 20. Phenoxyethanol 0.5 21. BHT 0.1 22. Fragrance 0.1 23. Titanium oxide 3 24. Iron oxide 1 25. Yellow 4 2 26. Red 202 1 Note 13: Refined candelilla wax SR-3 (Nippon Natural Products Co., Ltd.) Note 14: Leopearl TL2 (Chiba Flour Milling Co., Ltd.) Note 15: Pearleem 24 (NOF Corporation)

[0091] [Manufacturing Method] A: Components (1) to (4) are heated to 70°C and mixed uniformly. B: Component (5) is heated to 70°C. C: B is gradually added to A and dispersed using a Desper Mixer. D: C is cooled to room temperature and subjected to high-pressure processing using a microfluidizer to prepare a liposome dispersion. The liposome composition prepared here was confirmed to be a multilamellar vesicle consisting of a multilayer bilayer membrane structure. E: Components (6) to (26) are heated to 85°C and mixed uniformly. F: D, heated to 85°C, is gradually added to E and dispersed uniformly. G: F is filled into a stick-shaped container at 80°C and cooled to obtain a solid water-in-oil cosmetic (lipstick).

[0092] The solid water-in-oil cosmetic (lipstick) of Example 13 was excellent in "stability (of the solid water-in-oil cosmetic) immediately after production," "stability (of the solid water-in-oil cosmetic) immediately after production," and "vesicle (liposome) stability." Furthermore, good results were obtained in occlusion, removal feel, and spreadability upon application. The penetration load value was also rated C.

[0093] Example 14: Solid water-in-oil cosmetic (moisturizing balm) (Ingredients) (% by mass) 1. Hydrogenated soybean phospholipid 0.5 2. Cholesterol Note 1 0.1 3. 1,3-butylene glycol 2 4. Glycerin 2 5. Dipropylene glycol 1 6. Purified water 10 7. Niacinamide 4 8. Tranexamic acid 3 9. Purified water 20 10. Paraffin Note 3 5 11. Microcrystalline wax Note 4 5 12. Rice bran wax Note 5 1 13. Silica dimethyl silylate Note 6 2 14. Lauryl polyglyceryl-3 polydimethyl siloxyethyl dimethicone Note 7 5 15. Polyglyceryl-2 triisostearate Note 9 5 16. Hydrogenated polyisobutene Note 10 4 17. Hydrogenated polyisobutene Note 16 1 18. Mineral oil Note 11 10 19. Diisostearyl malate 5 20. Triethylhexanoin Remaining amount 21. Dimethicone (kinematic viscosity 10 mm at 25°C) ２ / s) 5 22. Phenoxyethanol 0.5 23. BHT 0.1 24. Fragrance 0.1 Note 16: Pearleem 46 (NOF Corporation)

[0094] [Manufacturing Method] A: Components (1) to (5) were heated to 70°C and mixed uniformly. B: Component (6) was heated to 70°C. C: B was gradually added to A and dispersed using a Desper Mixer. D: C was cooled to room temperature and subjected to high-pressure processing using a microfluidizer to prepare a liposome dispersion. The liposome composition prepared here was confirmed to be a multilamellar vesicle with a multilayer bilayer structure. E: Components (7) to (9) were mixed uniformly at room temperature and then added to D. F: Components (10) to (24) were heated to 85°C and mixed uniformly. G: E, heated to 85°C, was gradually added to F and dispersed uniformly. H: G was filled into a resin jar (40H x 56W x 56LMCW-50, Takemoto Container Co., Ltd.) at 80°C and cooled to obtain a solid water-in-oil cosmetic (moisturizing balm).

[0095] The solid water-in-oil cosmetic (moisturizing balm) of Example 14 was excellent in "stability (of solid water-in-oil cosmetic) immediately after production," "stability (of solid water-in-oil cosmetic) immediately after production," and "vesicle (liposome) stability." Furthermore, good results were obtained in occlusion, removal feel, and spreadability upon application. The penetration load value was also rated A.

[0096] Example 15: Solid water-in-oil cosmetic (cream) (Ingredients) (% by mass) 1. Hydrogenated soybean phospholipid 0.5 2. Cholesterol Note 2 0.1 3. 1,3-butylene glycol 2 4. Glycerin 2 5. Dipropylene glycol 1 6. Purified water 10 7. L-ascorbic acid 2-glucoside 3 8. Sodium monohydrogen phosphate 0.1 9. Sodium dihydrogen phosphate 0.1 10. Sodium hydroxide 0.3 11. Purified water 30 12. Paraffin Note 3 2 13. Microcrystalline wax Note 4 2 14. Carnauba wax 1 15. Silica dimethyl silylate Note 6 2 16. Disteardimonium hectorite Note 17 1 17. Lauryl polyglyceryl-3 polydimethyl siloxyethyl dimethicone Note 7 5 18. Polyglyceryl-2 triisostearate Note 9 5 19. Hydrogenated polyisobutene Note 10 5 20. Mineral oil Note 11 10 21. Shea butter 1 22. Diisostearyl malate 5 23. Triethylhexanoin balance 24. Dimethicone (kinematic viscosity 6mm at 25°C) ２ / s) 5 25. Dimethicone (kinematic viscosity 10 mm at 25 ° C. ２ / s) 3 26. Dimethicone (kinematic viscosity 100 mm at 25 ° C. ２ / s) 2 27. Phenoxyethanol 0.5 28. BHT 0.1 29. Fragrance 0.1 Note 17: BENTONE 38V (manufactured by Elementis)

[0097] [Manufacturing Method] A: Components (1) to (5) were heated to 70°C and mixed uniformly. B: Component (6) was heated to 70°C. C: B was gradually added to A and dispersed using a Desper Mixer. D: C was cooled to room temperature and subjected to high-pressure processing using a microfluidizer to prepare a liposome dispersion. The liposome composition prepared here was confirmed to be a multilamellar vesicle with a multilayer bilayer structure. E: Components (7) to (11) were mixed uniformly at room temperature and then added to D. F: Components (12) to (29) were heated to 85°C and mixed uniformly. G: E, heated to 85°C, was gradually added to F and dispersed uniformly. H: G was filled into a resin jar (40H x 56W x 56LMCW-50, Takemoto Container Co., Ltd.) at 80°C and cooled to obtain a solid water-in-oil cosmetic (cream).

[0098] The solid water-in-oil cosmetic (cream) of Example 15 was excellent in "stability (of the solid water-in-oil cosmetic) immediately after production," "stability (of the solid water-in-oil cosmetic) immediately after production," and "vesicle (liposome) stability." Furthermore, good results were obtained in occlusion, removal feel, and spreadability upon application. The penetration load value was also rated B.

[0099] Example 16: Solid water-in-oil cosmetic (lip balm) (Ingredients) (% by mass) 1. Hydrogenated soybean phospholipid 0.5 2. Phytosterol Note 2 0.1 3. 1,3-butylene glycol 2 4. Glycerin 2 5. Purified water 10 6. Paraffin Note 3 5 7. Microcrystalline wax Note 4 5 8. Silica dimethyl silylate Note 6 2 9. Disteardimonium hectorite Note 17 1 10. Lauryl polyglyceryl-3 polydimethylsiloxyethyl dimethicone Note 7 5 11. Polyglyceryl-2 triisostearate Note 9 5 12. Polyglyceryl-2 diisostearate Note 12 5 13. Hydrogenated polyisobutene Note 10 10 14. Mineral oil Note 11 20 15. Diisostearyl malate 10 16. Triethylhexanoin Remaining amount 17. Dimethicone (kinematic viscosity 10 mm at 25 ° C) ２ / s) 5 18. Phenoxyethanol 0.5 19. BHT 0.1 20. Tocopherol 0.1 21. Ceramide NG 0.1 22. Ceramide NP 0.1 23. Fragrance 0.1 24. Titanium oxide 2 25. Iron oxide 2 26. Yellow 4 1 27. Red 20 2 1

[0100] [Manufacturing Method] A: Components (1) to (4) are heated to 70°C and mixed uniformly. B: Component (5) is heated to 70°C. C: B is gradually added to A and dispersed using a Desper Mixer. D: C is cooled to room temperature and subjected to high-pressure processing using a microfluidizer to prepare a liposome dispersion. The liposome composition prepared here was confirmed to be a multilamellar vesicle with a multilayer bilayer membrane structure. E: Components (6) to (27) are heated to 85°C and mixed uniformly. F: D, heated to 85°C, is gradually added to E and dispersed uniformly. G: F is filled into a resin jar (40H x 56W x 56L MCW-50, manufactured by Takemoto Container Co., Ltd.) at 80°C and cooled to obtain a solid water-in-oil cosmetic (lip balm).

[0101] The solid water-in-oil cosmetic (lip balm) of Example 16 was excellent in "stability (of solid water-in-oil cosmetic) immediately after production," "stability (of solid water-in-oil cosmetic) immediately after production," and "vesicle (liposome) stability." Furthermore, good results were obtained in occlusion, removal feel, and spreadability upon application. The penetration load value was also rated A.

[0102] Example 17: Solid water-in-oil cosmetic (moisturizing balm) (Ingredients) (% by mass) 1. Hydrogenated soybean phospholipid 0.5 2. Cholesterol Note 1 0.1 3. 1,3-butylene glycol 2 4. Glycerin 2 5. Dipropylene glycol 1 6. Purified water 10 7. Niacinamide 4 8. Tranexamic acid 3 9. Purified water 20 10. Paraffin Note 3 5 11. Microcrystalline wax Note 4 5 12. Rice bran wax Note 5 1 13. Silica dimethyl silylate Note 6 2 14. Disteardimonium hectorite Note 17 1 15. Lauryl polyglyceryl-3 polydimethylsiloxyethyl dimethicone Note 7 5 16. Polyglyceryl-2 triisostearate Note 9 5 17. Hydrogenated polyisobutene Note 10 5 18. Mineral oil Note 11 10 19. Diisostearyl malate 5 20. Triethylhexanoin Remaining amount 21. Dimethicone (kinematic viscosity 100mm at 25°C) ２ / s) 5 22. Phenoxyethanol 0.5 23. BHT 0.1 24. Fragrance 0.1 25. Titanium oxide 1

[0103] [Manufacturing Method] A: Components (1) to (5) were heated to 70°C and mixed uniformly. B: Component (6) was heated to 70°C. C: B was gradually added to A and dispersed using a Desper Mixer. D: C was cooled to room temperature and subjected to high-pressure processing using a microfluidizer to prepare a liposome dispersion. The liposome composition prepared here was confirmed to be a multilamellar vesicle with a multilayer bilayer structure. E: Components (7) to (9) were mixed uniformly at room temperature and then added to D. F: Components (10) to (25) were heated to 85°C and mixed uniformly. G: E, heated to 85°C, was gradually added to F and dispersed uniformly. H: G was filled into a resin jar (40H x 56W x 56L MCW-50, manufactured by Takemoto Container Co., Ltd.) at 80°C and cooled to obtain a solid water-in-oil cosmetic (moisturizing balm).

[0104] The solid water-in-oil cosmetic (moisturizing balm) of Example 17 was excellent in "stability (of solid water-in-oil cosmetic) immediately after production," "stability (of solid water-in-oil cosmetic) immediately after production," and "vesicle (liposome) stability." Furthermore, good results were obtained in occlusion, removal feel, and spreadability upon application. The penetration load value was also rated A.

[0105] Example 18: Solid water-in-oil cosmetic (moisturizing balm) (Ingredients) (% by mass) 1. Hydrogenated soybean phospholipid 2 2. Phytosterol Note 1 0.4 3. 1,3-butylene glycol 4 4. Glycerin 4 5. Purified water 60 6. Paraffin Note 3 3 7. Microcrystalline wax Note 4 3 8. Dimethyl silylated silica Note 6 1 9. Lauryl polyglyceryl-3 polydimethylsiloxyethyl dimethicone Note 7 7 10. Polyglyceryl-2 triisostearate Note 9 1 11. Polyglyceryl-2 diisostearate Note 12 1 12. Hydrogenated polyisobutene Note 10 1 13. Hydrogenated polyisobutene Note 15 1 14. Mineral oil Note 11 3 15. Diisostearyl malate 2 16. Triethylhexanoin remaining amount 17. Dimethicone (kinematic viscosity 100 mm at 25°C) ２ / s) 3 18. Phenoxyethanol 0.5 19. BHT 0.1 20. Tocopherol 0.1 21. Ceramide NG 0.1 22. Ceramide NP 0.1 23. Fragrance 0.1

[0106] [Manufacturing Method] A: Components (1) to (4) are heated to 70°C and mixed uniformly. B: Component (5) is heated to 70°C. C: B is gradually added to A and dispersed using a Desper Mixer. D: C is cooled to room temperature and subjected to high-pressure processing using a microfluidizer to prepare a liposome dispersion. The liposome composition prepared here was confirmed to be a multilamellar vesicle with a multilayer bilayer membrane structure. E: Components (6) to (23) are heated to 85°C and mixed uniformly. F: D, heated to 85°C, is gradually added to E and dispersed uniformly. G: F is filled into a resin jar (40H x 56W x 56L MCW-50, manufactured by Takemoto Container Co., Ltd.) at 80°C and cooled to obtain a solid water-in-oil cosmetic (moisturizing balm).

[0107] The solid water-in-oil cosmetic (moisturizing balm) of Example 18 was excellent in "stability (of solid water-in-oil cosmetic) immediately after production," "stability (of solid water-in-oil cosmetic) immediately after production," and "vesicle (liposome) stability." Furthermore, good results were obtained in terms of removal feel and spreadability upon application. The penetration load value was also rated A.

Claims

Component (A) Vesicle Composition Component (B) Oily Gelling Agent Component (C) Lipophilic Surfactant Contains at least A solid water-in-oil cosmetic.

2. The solid water-in-oil cosmetic preparation according to claim 1, wherein the component (A) is a liposome composition. The component (A) is Component (a1) Phospholipid Component (a2) Sterols Component (a3) ​​Polyhydric alcohol 3. The solid water-in-oil cosmetic preparation according to claim 2, which is a liposome composition containing at least 3. The solid water-in-oil cosmetic according to claim 1, wherein the component (B) contains at least a component (b1) wax.

5. The solid water-in-oil cosmetic according to claim 4, wherein the content of the component (b1) is 1 to 30% by mass based on the total amount of the cosmetic.

5. The solid water-in-oil cosmetic according to claim 4, wherein the component (B) contains an oily gelling agent other than the component (b1) wax and the component (b2) wax.

7. The solid water-in-oil cosmetic according to claim 6, wherein the component (b2) is at least one selected from the group consisting of dextrin fatty acid esters, sucrose fatty acid esters, inulin fatty acid esters, 12-hydroxystearic acid, metal soaps, organically modified clay minerals, amino acid-based gelling agents, and inorganic powders.

8. The solid water-in-oil cosmetic according to claim 7, wherein the component (b2) is an inorganic powder.

3. The solid water-in-oil cosmetic according to claim 1, further comprising a component (D) glycerin fatty acid ester (excluding the component (C)).

3. The solid water-in-oil cosmetic according to claim 1, wherein the water content is 80% by mass or less based on the total amount of the cosmetic.

3. The solid water-in-oil cosmetic according to claim 1, wherein the cosmetic has a penetration load value of 50 to 500 gf.

3. The solid water-in-oil cosmetic according to claim 1, wherein the cosmetic is a skin care cosmetic.

3. The solid water-in-oil cosmetic according to claim 1, wherein the cosmetic is a lip cosmetic.

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