Insecticidal composition comprising sulfoxaflore, chlorfenapyr and pymetrozine or pyrifluquinazon

Abstract

The present invention relates to stable synergistic insecticidal composition for synergistic and effective control of various insect pests including entire sucking pests complex. The present invention also relates to a process for preparation thereof.

Description

[0001] INSECTICIDAL COMPOSITION COMPRISING SULFOXAFLORE, CHLORFENAPYR AND PYMETROZINE OR PYRIFLUQUINAZON

[0002] FIELD OF THE INVENTION

[0003] The present invention relates to stable synergistic insecticidal composition comprising A) compound of Formula I, chemically known as A-[methyloxido[l-[6-(trifhioromethyl)-3-pyridinyl]ethyl]-X4- sulfanylidene]cyanamide or its agrochemically acceptable salts, esters and derivatives; B) compound of Formula II, chemically known as

[0004] 4-bromo-2-(4-chlorophenyl)- 1 -(ethoxymethyl)-5-(trifluoromethyl)- lH-pyrrole-3-carbonitrile or its agrochemically acceptable salts, esters and derivatives; and C) at least one pyridine azomethine insecticide selected from pymetrozine and pyrifluquinazon or its agrochemically acceptable salts, esters and derivatives for synergistic and effective control of various insects pests including sucking pests complex. The present invention also relates to a process for preparation of such insecticidal composition for synergistic and efficacious control of various insects-pests including entire sucking-pests complex.

[0005] BACKGROUND OF THE INVENTION

[0006] Background description includes information that may be useful in understanding the present invention. It is not an admission that any of the information provided herein is prior art or relevant to the presently claimed invention.

[0007] Insects pests pose significant challenges to agricultural productivity, public health and overall ecosystem balance. The development of effective insecticidal composition is crucial for mitigating these impacts. Traditional practices often relying on single active ingredients, face the problem of environmental impact, resistance development in target insects-pests populations. Furthermore, the aging process in plants can significantly impact their growth and productivity, requiring effective anti-aging solutions to ensure optimal plant performance.

[0008] Conventional insecticidal formulations struggle to provide long-term control and rapid knock down effects, primarily due to the development of resistance in target pest populations. Insecticide resistance has become a significant concern, severely compromising the effectiveness of traditional insecticides. Moreover, these formulations often have detrimental effects on non-target organisms and the environment, raising serious issues related to phytotoxicity, discoloration of leaves and other damages to plants. Compounding these challenges, the natural ageing of plant influences various physiological and biochemical processes, leading to reduced growth, decreased resistance to environmental stresses, and diminished overall health and productivity.

[0009] Numerous insecticidal compositional have been developed, each tailored based on the active ingredients used and their intended applications. Insecticides for agriculture purpose are available both in the pure form and as well as incorporated into agrochemical formulations, which typically comprise one or more active ingredients and additional excipients substances that enhance the effects and facilitate the application thereof, such as carriers, adjuvants or additives.

[0010] Various prior art documents disclose compositions comprising combinations of insecticides. However, many of these existing insecticidal compositions exhibit phytotoxic effects, thereby negatively impacting plant health and crop yield. Furthermore, they often lack efficacy in both pre -emergence and postemergence applications and fail to provide broad-spectrum control across a wide range of crops

[0011] Reference can be made to CN102210320A, which discloses insecticidal composition comprising Sulfoxaflor and pyrethroid, wherein the weight percentage ratio of the two active ingredients is (1 -80):(50- 0.1), and preferably, the weight percentage ratio is (5 -45):(25-0.1).

[0012] Reference can be made to CN102246766A, which discloses insecticidal composition comprising flonicamid and the pymetrozine, wherein a weight ratio of the two active ingredients is (l-80):(85-l), and preferably is (5 -40): (75 -10).

[0013] However, existing insecticidal combinations often exhibit adverse effects on plants and crops, including leaf discoloration and reduced plant vigor. Additionally, they may contribute to the development of resistance in sucking pest complexes and are generally ineffective in controlling all life stages of pests such as thrips, whiteflies, aphids, jassids, and the like.

[0014] Therefore, there is an urgent need for advanced insecticidal compositions that not only address resistance issues but also minimize adverse environmental impacts and support plant health, ensuring sustainable and effective insect pests management solutions. The stable synergistic insecticidal composition of present invention represents a strategic advancement in pest control. By leveraging multiple active ingredients with complementary mode of action, the present invention offers improved efficacy, resistance management and environmental safety, contributing to more effective and sustainable insect pests’ management solutions.

[0015] The stable synergistic insecticidal ternary composition of the present invention provides several advantages over traditional or conventional insecticidal formulations such as enhanced insect control efficacy against a wide range of insect pests, anti-aging effects thereby promoting plant greening, vigour and preventing discolouration apart from stimulating plant growth and strengthening plant defences against biotic and abiotic stressors. Furthermore, it minimizes the development of resistance amongst sucking pests complex such as thrips, white fly, aphids and Jassids etc., due to the multi-level and mode of action including knock down action of its constituents. The composition of present invention also has the potential to mitigate yield losses caused by aging of the plants and insect pest attack and thus improves long-term crop productivity by rejuvenating plants and crops.

[0016] Therefore, there is a need for a stable synergistic insecticidal composition that is highly efficient, non- toxic, covers insect pest control of broader spectrum of insects including sucking pests complex and is environment friendly, non- phytotoxic and economical.

[0017] A compound of Formula I chemically known as 7V-[methyloxido[l-[6-(trifluoromethyl)-3-pyridinyl]ethyl]- X4-sulfanylidene]cyanamide, is a systemic insecticide belongs to sulfoximine class. It is a Nicotinic acetylcholine receptor (nAChR) competitive modulator. It is used for the control of aphids in various crops such as tomatoes, peppers, aubergines, cucumbers, melons, courgettes; cereals including wheat, rye, barley, oats, triticale; Cotton etc.

[0018] A compound of formula II, chemically known as 4-bromo-2-(4-chlorophenyl)-l-(ethoxymethyl)-5- (trifluoromethyl)-lH-pyrrole-3-carbonitrile is a broad-spectrum insecticide belongs to the class of arylpyrole. It has a systemic activity and has mainly stomach action but has some contact action also. It is a uncoupler of oxidative phosphorylation. It is a pro-insecticide used to control spider mites, caterpillars, thrips, fungus gnats, including termites, cockroaches, ants, bedbugs, flies and spiders. It has a low aqueous solubility, low volatility and, based on its chemical properties, would not normally be expected to leach to groundwater. It is not usually persistent in soil or water systems.

[0019] Pyridine azomethine insecticides are a specialized class of chemical agents known for their unique mode of action against various insects-pests. These compounds such Pymetrozine and pyrifluquinazon target the chordotonal organs in insects, which are responsible for their feeding behaviour and coordination. By disrupting these sensory structures, pyridine azomethines effectively impair the insect’s ability to feed, leading to starvation and eventual death. This mode of action makes them particularly effective against homopteran pests like aphids, whiteflies, and planthoppers, which rely heavily on continuous feeding for survival. Additionally, pyridine azomethine insecticides are valued for their selective toxicity, meaning they pose minimal risk to non-target organisms, including beneficial insects and predators. Their efficacy in managing pest populations, combined with their environmentally friendly profile, makes pyridine azomethine insecticides a valuable tool in integrated pest management programs. They offer a promising solution for sustainable agriculture and helps to mitigate resistance development in pest populations.

[0020] For the reasons mentioned above, there exists a need to provide a stable synergistic insecticidal composition for synergistic and effective control of insect pests including sucking pests complex.

[0021] The present invention satisfies the existing needs, as well as others, and generally overcomes the deficiencies found in the prior art.

[0022] The present invention composition is synergistic, efficacious, environmentally friendly, simple to formulate, stable and is safe to use.

[0023] Thus, a insecticidal composition of the present invention aims to overcome the problems of the prior art and provides a stable synergistic insecticidal composition comprising bioactive amounts of A) compound of Formula I, chemically known as A-[methyloxido[l -[6-(trifhioromethyl)-3-pyridinyl]ethyl]-X4- sulfanylidene]cyanamide or its agrochemically acceptable salts, esters and derivatives; B) Compound of Formula II, chemically known as

[0024] 4-bromo-2-(4-chlorophenyl)- 1 -(ethoxymethyl)-5-(trifluoromethyl)- lH-pyrrole-3-carbonitrile or its agrochemically acceptable salts, esters and derivatives; and C) at least one pyridine azomethine insecticide selected from pymetrozine and pyrifluquinazon or its agrochemically acceptable salts, esters and derivatives for synergistic and effective control of various insects pests including entire sucking pests complex.

[0025] The present invention also provides a novel method of preparing composition of present invention, which is stable as well as provide desired bio-efficacy, synergy. Embodiments of the present invention may therefore ameliorate one or more of the above-mentioned problems.

[0026] OBJECTIVES AND ADVANTAGES OF THE INVENTION

[0027] The main objective of present invention is to provide a novel and effective stable synergistic insecticidal composition demonstrating high efficacy and to provide complete protection to crops and plants against insect-pests including entire sucking-pests complex.

[0028] It is another objective of the present invention to provide improved, stable and ready to use stable insecticidal composition having synergistic and superior properties for effective control of insect pests including sucking pests complex such as hoppers, aphids, white flies and jassids. It is yet another objective of the present invention is to provide a stable synergistic insecticidal composition comprising A) compound of Formula I, chemically known as A-[methyloxido[l-[6- (trifluoromethyl)-3-pyridinyl]ethyl]-X4-sulfanylidene]cyanamide or its agrochemically acceptable salts, esters and derivatives; B) compound of Formula II, chemically known as 4-bromo-2-(4-chlorophenyl)- 1 -(ethoxymethyl)-5-(trifluoromethyl)- lH-pyrrole-3-carbonitrile or its agrochemically acceptable salts, esters and derivatives; and C) at least one pyridine azomethine insecticide selected from pymetrozine and pyrifluquinazon or its agrochemically acceptable salts, esters and derivatives for synergistic and effective control of various insects pests including sucking pests complex.

[0029] It is yet another objective of the present invention is to provide a stable synergistic insecticidal composition that provides effective immediate and long-term effective control and knock down of insect pests including sucking pests complex at all developmental stages of insects such as egg, nymph, larva, pupa, and adult.

[0030] It is yet another objective of the present invention to provide a composition and method for insect pest control that is both effective in the short and long term.

[0031] It is yet another objective of the present invention to provide a stable synergistic insecticidal composition which can be easily formulated.

[0032] It is yet another objective of the present invention to provide a stable synergistic insecticidal composition which prevents ageing effect and discoloration of plants leaves.

[0033] It is yet another objective of the present invention is to provide a stable synergistic insecticidal composition that promotes plant health, growth and thus increases plant, crop yield in the field.

[0034] It is yet another objective of the present invention to provide a novel and effective stable synergistic insecticidal composition which is environmentally safe, possesses broad spectrum bio-efficacy, is non- phytotoxic.

[0035] It is yet another objective of the present invention is to provide a process for preparing a stable synergistic insecticidal composition comprising A) compound of Formula I, chemically known as A-[methyloxido[l- [6-(trifluoromethyl)-3-pyridinyl]ethyl]-X4-sulfanylidene]cyanamide or its agrochemically acceptable salts, esters and derivatives; B) compound of Formula II, chemically known as 4-bromo-2-(4-chlorophenyl)- 1 -(ethoxymethyl)-5-(trifluoromethyl)- lH-pyrrole-3-carbonitrile or its agrochemically acceptable salts, esters and derivatives; and C) at least one pyridine azomethine insecticide selected from pymetrozine and pyrifluquinazon or its agrochemically acceptable salts, esters and derivatives for synergistic and effective control of various insects pests including sucking pests complex.

[0036] Advantages of the present invention are as below:

[0037] • The stable synergistic insecticidal composition of present invention has broad spectrum activity against sucking complex pests including but not limited to thrips, whitefly, aphids, jassids, diamond back moth, hoppers, mites, bollworms, shoot, stem, fruit borer, brown plant hopper, white backed plant hopper, cotton mealy bug, diamond black moth, girdle beetle, semi looper and tobacco caterpillar etc.

[0038] • The stable synergistic insecticidal composition of the present invention has anti-ageing effect on plants and crops.

[0039] • The stable synergistic insecticidal composition of the present invention is effective against insect pests including sucking pests complex at all developmental stages of insects such as egg, nymph, larva, pupa, and adult.

[0040] • The stable synergistic insecticidal composition of the present invention prevents dis -coloration of leaves.

[0041] • The stable synergistic insecticidal composition of the present invention enhances tenderness in plants and crops.

[0042] • The stable synergistic insecticidal composition of the present invention shows knock down effect on insect pests including sucking pests complex such as hoppers, aphids, white flies and jassids.

[0043] • The stable synergistic insecticidal composition of the present invention has high controlling effects against existing insects resistant to chemicals, and no chemical damage against plants is observed.

[0044] • The stable synergistic insecticidal composition of present invention is economically beneficial to the farmers as it provides better yield in of the crop with less no. of sprays.

[0045] • The stable synergistic insecticidal composition of present invention is storage stable.

[0046] • The stable synergistic insecticidal composition of the present invention shows no phytotoxicity effect. The stable synergistic insecticidal composition of present invention is environmental friendly and is highly active against diseases in the soil caused by various insect pests including those that mostly occur in the early stages of plant development.

[0047] SUMMARY OF THE INVENTION

[0048] In summary, the main aspect of the present is to provide a stable synergistic insecticidal composition having high insects-pests including entire sucking-pests complex control efficacy.

[0049] Accordingly, the present invention relates to a stable synergistic insecticidal composition comprising: A) compound of Formula I, chemically known as 7V-[methyloxido[l-[6-(trifluoromethyl)-3-pyridinyl]ethyl]- X4-sulfanylidene]cyanamide or its agrochemically acceptable salts, esters and derivatives; B) Compound of Formula II, chemically known as

[0050] 4-bromo-2-(4-chlorophenyl)- 1 -(ethoxymethyl)-5-(trifluoromethyl)- lH-pyrrole-3-carbonitrile or its agrochemically acceptable salts, esters and derivatives; and C) at least one pyridine azomethine insecticide selected from pymetrozine and pyrifluquinazon or its agrochemically acceptable salts, esters and derivatives for synergistic and effective control of various insects pests including sucking pests complex.

[0051] In another aspect, a stable synergistic insecticidal composition of the present invention is environmentally safe, stable, safe to handle, improved rain fastness, increased active ingredients uptake and cost effective.

[0052] In another aspect, the present invention providess a stable synergistic insecticidal composition comprising:

[0053] A) compound of Formula I, chemically known as A-[methyloxido[l-[6-(trifluoromethyl)-3- pyridinyl]ethyl]-X4-sulfanylidene]cyanamide or its agrochemically acceptable salts, esters and derivatives;

[0054] B) compound of Formula II, chemically known as 4-bromo-2-(4-chlorophenyl)-l-(ethoxymethyl)-5-(trifluoromethyl)-lH-pyrrole-3-carbonitrile or its agrochemically acceptable salts, esters and derivatives; and

[0055] C) at least one pyridine azomethine insecticide selected from pymetrozine and pyrifluquinazon or its agrochemically acceptable salts, esters and derivatives.

[0056] In another aspect, the present invention provides a stable synergistic insecticidal composition comprising: A) compound of Formula I, chemically known as A-[methyloxido[l-[6-(trifluoromethyl)-3- pyridinyl]ethyl]-X4-sulfanylidene]cyanamide or its agrochemically acceptable salts, esters and derivatives, present in the range of 0.1-90% by weight of the composition.

[0057] B) compound of Formula II, chemically known as 4-bromo-2-(4-chlorophenyl)-l-(ethoxymethyl)-5-(trifluoromethyl)-lH-pyrrole-3-carbonitrile or its agrochemically acceptable salts, esters and derivatives, present in the range of 0.1-90% by weight of the composition; and

[0058] C) at least one pyridine azomethine insecticide selected from pymetrozine and pyrifluquinazon or its agrochemically acceptable salts, esters and derivatives, present in the range of 0.1-90% by weight of the composition.

[0059] In another aspect, the present invention provides a stable synergistic insecticidal composition comprising:

[0060] A) compound of Formula I, chemically known as A-[methyloxido[l-[6-(trifluoromethyl)-3- pyridinyl]ethyl]-X4-sulfanylidene]cyanamide or its agrochemically acceptable salts, esters and derivatives, present in the range of 0.1-90% by weight of the composition

[0061] B) compound of Formula II, chemically known as 4-bromo-2-(4-chlorophenyl)-l-(ethoxymethyl)-5-(trifluoromethyl)-lH-pyrrole-3-carbonitrile or its agrochemically acceptable salts, esters and derivatives, present in the range of 0.1-90% by weight of the composition;

[0062] C) at least one pyridine azomethine insecticide selected from pymetrozine and pyrifluquinazon or its agrochemically acceptable salts, esters and derivatives, present in the range of 0.1-90% by weight of the composition; and

[0063] D) one or more agrochemically acceptable excipients.

[0064] In another aspect, the present invention provides a stable synergistic insecticidal composition comprising:

[0065] A) compound of Formula I, chemically known as A-[methyloxido[l-[6-(trifluoromethyl)-3- pyridinyl]ethyl]-X4-sulfanylidene]cyanamide or its agrochemically acceptable salts, esters and derivatives, present in the range of 0.1-90% by weight of the composition

[0066] B) compound of Formula II, chemically known as 4-bromo-2-(4-chlorophenyl)-l-(ethoxymethyl)-5-(trifluoromethyl)-lH-pyrrole-3-carbonitrile or its agrochemically acceptable salts, esters and derivatives, present in the range of 0.1-90% by weight of the composition; C) at least one pyridine azomethine insecticide selected from pymetrozine and pyrifluquinazon or its agrochemically acceptable salts, esters and derivatives, present in the range of 0.1-90% by weight of the composition; and

[0067] D) at least one or more additives.

[0068] In another aspect, the present invention provides a stable synergistic insecticidal composition comprising:

[0069] A) compound of Formula I, chemically known as A-[methyloxido[l-[6-(trifluoromethyl)-3- pyridinyl]ethyl]-X4-sulfanylidene]cyanamide or its agrochemically acceptable salts, esters and derivatives, present in the range of 0.1-90% by weight of the composition

[0070] B) compound of Formula II, chemically known as 4-bromo-2-(4-chlorophenyl)-l-(ethoxymethyl)-5-(trifluoromethyl)-lH-pyrrole-3-carbonitrile or its agrochemically acceptable salts, esters and derivatives, present in the range of 0.1-90% by weight of the composition;

[0071] C) at least one pyridine azomethine insecticide selected from pymetrozine and pyrifluquinazon or its agrochemically acceptable salts, esters and derivatives, present in the range of 0.1-90% by weight of the composition; and

[0072] D) at least one or more additives selected from Silwet Power, tallow amine ethoxylate, ammonium sulphate, and Epoxide soybean oil either alone or in combination thereof.

[0073] In another aspect, the present invention provides a stable synergistic insecticidal composition comprising:

[0074] A) compound of Formula I, chemically known as A-[methyloxido[l-[6-(trifluoromethyl)-3- pyridinyl]ethyl]-X4-sulfanylidene]cyanamide or its agrochemically acceptable salts, esters and derivatives, present in the range of 0.1-90% by weight of the composition

[0075] B) compound of Formula II, chemically known as 4-bromo-2-(4-chlorophenyl)-l-(ethoxymethyl)-5-(trifluoromethyl)-lH-pyrrole-3-carbonitrile or its agrochemically acceptable salts, esters and derivatives, present in the range of 0.1-90% by weight of the composition;

[0076] C) at least one pyridine azomethine insecticide selected from pymetrozine and pyrifluquinazon or its agrochemically acceptable salts, esters and derivatives, present in the range of 0.1-90% by weight of the composition;

[0077] D) at least one or more additives selected from Silwet Power, tallow amine ethoxylate, ammonium sulphate, and Epoxide soybean oil either alone or in combination thereof, present in the range of 0.01 - 20% by weight of the composition; and

[0078] E) one or more agrochemically acceptable excipients. In yet another preferred aspect, the present invention provides a stable synergistic insecticidal composition comprising:

[0079] A) compound of Formula I, chemically known as A-[methyloxido[l-[6-(trifluoromethyl)-3- pyridinyl]ethyl]-X4-sulfanylidene]cyanamide or its agrochemically acceptable salts, esters and derivatives, present in the range of 0.1-90% by weight of the composition

[0080] B) compound of Formula II, chemically known as 4-bromo-2-(4-chlorophenyl)-l-(ethoxymethyl)-5-(trifluoromethyl)-lH-pyrrole-3-carbonitrile or its agrochemically acceptable salts, esters and derivatives, present in the range of 0.1-90% by weight of the composition and

[0081] C) Pymetrozine or its agrochemically acceptable salts, esters and derivatives, , present in the range of 0.1-90% by weight of the composition.

[0082] In yet another preferred aspect, the present invention provides a stable synergistic insecticidal composition comprising:

[0083] A) compound of Formula I, chemically known as A-[methyloxido[l-[6-(trifluoromethyl)-3- pyridinyl]ethyl]-X4-sulfanylidene]cyanamide or its agrochemically acceptable salts, esters and derivatives, present in the range of 0.1-90% by weight of the composition;

[0084] B) compound of Formula II, chemically known as 4-bromo-2-(4-chlorophenyl)-l-(ethoxymethyl)-5-(trifluoromethyl)-lH-pyrrole-3-carbonitrile or its agrochemically acceptable salts, esters and derivatives, present in the range of 0.1-90% by weight of the composition;

[0085] C) Pymetrozine or its agrochemically acceptable salts, esters and derivatives, , present in the range of 0.1-90% by weight of the composition; and

[0086] D) one or more agrochemically acceptable excipients.

[0087] In yet another preferred aspect, the present invention provides a stable synergistic insecticidal composition comprising:

[0088] A) compound of Formula I, chemically known as A-[methyloxido[l-[6-(trifluoromethyl)-3- pyridinyl]ethyl]-X4-sulfanylidene]cyanamide or its agrochemically acceptable salts, esters and derivatives, present in the range of 0.1-90% by weight of the composition

[0089] B) compound of Formula II, chemically known as 4-bromo-2-(4-chlorophenyl)-l-(ethoxymethyl)-5-(trifluoromethyl)-lH-pyrrole-3-carbonitrile or its agrochemically acceptable salts, esters and derivatives, present in the range of 0.1-90% by weight of the composition; C) Pymetrozine or its agrochemically acceptable salts, esters and derivatives, , present in the range of 0.1-90% by weight of the composition; and

[0090] D) at least one or more additives selected from Silwet Power, tallow amine ethoxylate, ammonium sulphate, and Epoxide soybean oil either alone or in combination thereof, present in the range of 0.01 - 20% by weight of the composition.

[0091] In yet another preferred aspect, the present invention provides a stable synergistic insecticidal composition comprising:

[0092] A) compound of Formula I, chemically known as A-[methyloxido[l-[6-(trifluoromethyl)-3- pyridinyl]ethyl]-X4-sulfanylidene]cyanamide or its agrochemically acceptable salts, esters and derivatives, present in the range of 0.1-90% by weight of the composition

[0093] B) compound of Formula II, chemically known as 4-bromo-2-(4-chlorophenyl)-l-(ethoxymethyl)-5-(trifluoromethyl)-lH-pyrrole-3-carbonitrile or its agrochemically acceptable salts, esters and derivatives, present in the range of 0.1-90% by weight of the composition;

[0094] C) Pymetrozine or its agrochemically acceptable salts, esters and derivatives, , present in the range of 0.1-90% by weight of the composition;

[0095] D) at least one or more additives selected from Silwet Power, tallow amine ethoxylate, ammonium sulphate, and Epoxide soybean oil either alone or in combination thereof, present in the range of 0.01 - 20% by weight of the composition; and

[0096] E) one or more agrochemically acceptable excipients.

[0097] In another aspect, the present invention provides a process for preparation of the stable synergistic insecticidal composition comprising:

[0098] A) compound of Formula I, chemically known as A-[methyloxido[l-[6-(trifluoromethyl)-3- pyridinyl]ethyl]-X4-sulfanylidene]cyanamide or its agrochemically acceptable salts, esters and derivatives;

[0099] B) compound of Formula II, chemically known as 4-bromo-2-(4-chlorophenyl)-l-(ethoxymethyl)-5-(trifluoromethyl)-lH-pyrrole-3-carbonitrile or its agrochemically acceptable salts, esters and derivatives; and

[0100] C) at least one pyridine azomethine insecticide selected from pymetrozine and pyrifluquinazon or its agrochemically acceptable salts, esters and derivatives.

[0101] In another aspect, the present insecticidal composition is stable and has enhanced shelf life. In another aspect, the present invention provides a stable synergistic insecticidal composition which has enhanced efficacy and penetration capacity.

[0102] DETAILED DESCRIPTION OF THE INVENTION

[0103] In describing the embodiments of the invention, specific terminology is resorted for sake of clarity. However, it is not intended that the invention be limited to specific terms so selected and it is to be understood that each specific term includes all technical equivalents that operate in a similar manner to accomplish a similar purpose.

[0104] Discussed below are some representative embodiments of the present invention. The invention in its broader aspects is not limited to the specific details and representative methods.

[0105] All technical and scientific terms used herein have the same meanings as commonly understood by someone ordinarily skilled in the art to which the present subject matter belongs.

[0106] The terminology used, in the present disclosure, is only for the purpose of explaining a particular embodiment and such terminology shall not be considered to limit the scope of the present disclosure.

[0107] As used in the present disclosure, the forms "a,” "an," and "the" may be intended to include the plural forms as well, unless the context clearly suggests otherwise. Thus, for example, reference to a composition containing “a compound” includes a mixture of two or more compounds. It should also be noted that the term “or” is generally employed in its sense including “and / or” unless the content clearly dictates otherwise.

[0108] The terms "comprises", "comprising", “including”, and “having” are open ended transitional phrases and therefore specify the presence of stated features, integers, steps, operations, elements, but do not forbid the presence or addition of one or more other features, integers, steps, operations, elements, components, and / or groups thereof. The particular order of steps disclosed in the method and process of the present disclosure is not to be construed as necessarily requiring their performance as described or illustrated. It is also to be understood that additional or alternative steps may be employed.

[0109] Variations or modifications to the composition of this invention, within the scope of the invention, may occur to those skilled in the art upon reviewing the disclosure herein. Such variations or modifications are well within the spirit of this invention. The expression of various quantities in terms of “% w / w” or “%” means the percentage by weight, relative to the weight of the total solution or composition unless otherwise specified.

[0110] The term “active ingredient” (a.i.) or “active agent” or “active” used herein refers to that component of the composition responsible for control of various insects-pests at the same time.

[0111] The term “crop” shall include a multitude of desired crop plants or an individual crop plant growing at a locus.

[0112] The term “synergistic”, as used herein, refers to the combined action of two or more active agents blended together and administered conjointly that is greater than the sum of their individual effects.

[0113] “Bioactive amounts” as mentioned herein means that amount which, when applied for treatment of crops, is sufficient to give effect in such treatment.

[0114] The term “control” means to inhibit the ability of insect pests to survive, grow, feed and / or reproduce, or to limit the insect pests’ related damage or loss in crop plants. To “control” insect pests may or may not mean killing the insects although, it preferably means killing the insect pests.

[0115] The term “health of a plant” or “plant health” is defined as a condition of the plant and / or its products. As a result of the improved health; yield, plant vigour, quality and tolerance to abiotic or biotic stress is increased. As a result, the health of a plant is increased even in the absence of pest pressure.

[0116] Accordingly, in an especially preferred embodiment according to the invention, the health of a plant is increased both in the presence and absence of biotic or abiotic stress factors. An increase in plant vigor may for example result in an increased yield and / or tolerance to abiotic or biotic stress.

[0117] One indicator for the condition of the plant is the yield. “Yield” is to be understood as any plant product of economic value that is produced by the plant such as grains, fruits, vegetables, nuts, grains, seeds, wood (e.g., in the case of silviculture plants) or even flowers (e.g. in the case of gardening plants, ornamentals). The plant products may in addition be further utilized and / or processed after harvesting.

[0118] In another preferred embodiment of the invention, the yield of the plants treated according to the method of the invention, is increased synergistically. In another especially preferred embodiment of the invention, the plant vigour of the treated plant is increased. In another preferred embodiment of the invention, the plant vigour of the plants treated according to the composition of the present invention is increased synergistically.

[0119] Another indicator for the condition of the plant is the “quality” of a plant and / or its products.

[0120] In an especially preferred embodiment of the invention, the quality of the treated plant is increased.

[0121] In another preferred embodiment of the invention, the quality of the plants treated according to the method of the invention, is increased synergistically.

[0122] The term rain fastness refers to the ability of a substance to remain effective after being applied to a surface and then exposed to rainfall or irrigation. In other words, it measures how well the substance adheres to the target surface and resists being washed away by water. A low rain fastness indicates that it may be washed off or diluted by rainfall, reducing its efficacy.

[0123] The term "Increased uptake of active ingredient" refers to the enhanced absorption or penetration of the active component of a substance into the target organism or plant. This increased uptake can lead to greater effectiveness of the product in controlling various insects-pests including sucking pests at the same time. It may occur through various mechanisms, such as improved formulation, adjuvants that enhance penetration, or modifications to the active ingredient itself to facilitate absorption. Overall, increased uptake of the active ingredient results in improved performance of the product in achieving its intended purpose.

[0124] The term “benefit: cost” refers to a ratio used in a cost-benefit analysis to summarize the overall relationship between the relative costs and benefits of a proposed composition. If a treatment has a benefit-cost ratio greater than 1.0, the treatment is expected to deliver a positive and better outcome.

[0125] In one embodiment of the present invention, the yield of the treated plant is increased.

[0126] In another embodiment of the present invention, there is synergistic and efficacious control of various insect-pests affecting the plants and crops.

[0127] Another embodiment of the present invention, includes within its scope, all possible salts, esters and derivatives of the active ingredients of the composition. It is also to be understood that the terminology used herein is for the purpose of describing particular embodiments of the invention only and is not intended to limit the scope of the invention in any manner. The use of examples anywhere in this specification including examples of any terms discussed herein is illustrative only, and in no way limits the scope and meaning of the invention or of any exemplified term. Likewise, the invention is not limited to various embodiments given in this specification.

[0128] Unless otherwise defined, all technical and scientific terms used herein have the same meaning as commonly understood by one of ordinary skill in the art to which this invention pertains. In the case of conflict, the present document, including definitions will control.

[0129] The composition or formulation according to the present invention has a reduced or zero phytotoxicity with respect to agricultural crops. This results in the present invention effective and possible in the selective control of insects-pest’s control.

[0130] In an embodiment, the stable synergistic insecticidal composition or formulation has a reduced or zero phytotoxicity with respect to important agricultural crops. This results in the present invention effective and possible in the selective control of insect-pests’.

[0131] It has been observed by the inventors of the present invention that the composition of present invention not only provides synergistic effect but also provides anti-aging effect to the crops or plants to which it is applied. In addition, the stable synergistic insecticidal composition of the present invention is effective against all developmental stages of insect pests including egg, nymph, larva, pupa, and adult.

[0132] The expression of various quantities in terms of “% w / w” or “%” means the percentage by weight, relative to the weight of the total formulation or composition unless otherwise specified.

[0133] The term “active ingredient” (a.i.) or “active agent” or “active” used herein refers to that component of the composition responsible for control and killing of insect pests.

[0134] Sucking pests complex include but is not limited to thrips, brown pant hopper, white backed plant hopper, rice leafhopper, aphids, jassids, white fly, mites.

[0135] Variations or modifications to the composition of this invention, within the scope of the invention, may occur to those skilled in the art upon reviewing the disclosure herein. Such variations or modifications are well within the spirit of this invention. In one embodiment of the present invention, a stable synergistic insecticidal composition comprising:

[0136] A) compound of Formula I, chemically known as A-[methyloxido[l-[6-(trifluoromethyl)-3- pyridinyl]ethyl]-X4-sulfanylidene]cyanamide or its agrochemically acceptable salts, esters and derivatives;

[0137] B) Compound of Formula II, chemically known as 4-bromo-2-(4-chlorophenyl)-l-(ethoxymethyl)-5-(trifluoromethyl)-lH-pyrrole-3-carbonitrile or its agrochemically acceptable salts, esters and derivatives; and

[0138] C) at least one pyridine azomethine insecticide selected from pymetrozine and pyrifluquinazon or its agrochemically acceptable salts, esters and derivatives.

[0139] In one embodiment of the present invention, a stable synergistic insecticidal composition comprising:

[0140] A) compound of Formula I, chemically known as A-[methyloxido[l-[6-(trifluoromethyl)-3- pyridinyl]ethyl]-X4-sulfanylidene]cyanamide or its agrochemically acceptable salts, esters and derivatives;

[0141] B) Compound of Formula II, chemically known as 4-bromo-2-(4-chlorophenyl)-l-(ethoxymethyl)-5-(trifluoromethyl)-lH-pyrrole-3-carbonitrile or its agrochemically acceptable salts, esters and derivatives;

[0142] C) at least one pyridine azomethine insecticide selected from pymetrozine and pyrifluquinazon or its agrochemically acceptable salts, esters and derivatives; and

[0143] D) one or more agrochemically acceptable excipients.

[0144] In one embodiment of the present invention, a stable synergistic insecticidal composition comprising:

[0145] A) compound of Formula I, chemically known as A-[methyloxido[l-[6-(trifluoromethyl)-3- pyridinyl]ethyl]-X4-sulfanylidene]cyanamide or its agrochemically acceptable salts, esters and derivatives;

[0146] B) Compound of Formula II, chemically known as 4-bromo-2-(4-chlorophenyl)-l-(ethoxymethyl)-5-(trifluoromethyl)-lH-pyrrole-3-carbonitrile or its agrochemically acceptable salts, esters and derivatives;

[0147] C) at least one pyridine azomethine insecticide selected from pymetrozine and pyrifluquinazon or its agrochemically acceptable salts, esters and derivatives; and

[0148] D) at least one or more additives.

[0149] In one embodiment of the present invention, a stable synergistic insecticidal composition comprising: A) compound of Formula I, chemically known as A-[methyloxido[l-[6-(trifluoromethyl)-3- pyridinyl]ethyl]-X4-sulfanylidene]cyanamide or its agrochemically acceptable salts, esters and derivatives;

[0150] B) Compound of Formula II, chemically known as 4-bromo-2-(4-chlorophenyl)-l-(ethoxymethyl)-5-(trifluoromethyl)-lH-pyrrole-3-carbonitrile or its agrochemically acceptable salts, esters and derivatives;

[0151] C) at least one pyridine azomethine insecticide selected from pymetrozine and pyrifluquinazon or its agrochemically acceptable salts, esters and derivatives; and

[0152] D) at least one or more additives selected from Silwet Power, tallow amine ethoxylate, ammonium sulphate, and Epoxide soybean oil either alone or in combination thereof.

[0153] In another embodiment of the present invention, a stable synergistic insecticidal composition comprising:

[0154] A) compound of Formula I, chemically known as A-[methyloxido[l-[6-(trifluoromethyl)-3- pyridinyl]ethyl]-X4-sulfanylidene]cyanamide or its agrochemically acceptable salts, esters and derivatives, present in the range of 0.1-90% by weight of the composition.

[0155] B) Compound of Formula II, chemically known as 4-bromo-2-(4-chlorophenyl)-l-(ethoxymethyl)-5-(trifluoromethyl)-lH-pyrrole-3-carbonitrile or its agrochemically acceptable salts, esters and derivatives, present in the range of 0.1-90% by weight of the composition; and

[0156] C) at least one pyridine azomethine insecticide selected from pymetrozine and pyrifluquinazon or its agrochemically acceptable salts, esters and derivatives, present in the range of 0.1-90% by weight of the composition.

[0157] In another embodiment of the present invention, a stable synergistic insecticidal composition comprising:

[0158] A) compound of Formula I, chemically known as A-[methyloxido[l-[6-(trifluoromethyl)-3- pyridinyl]ethyl]-X4-sulfanylidene]cyanamide or its agrochemically acceptable salts, esters and derivatives, present in the range of 0.1-90% by weight of the composition

[0159] B) Compound of Formula II, chemically known as 4-bromo-2-(4-chlorophenyl)-l-(ethoxymethyl)-5-(trifluoromethyl)-lH-pyrrole-3-carbonitrile or its agrochemically acceptable salts, esters and derivatives, present in the range of 0.1-90% by weight of the composition;

[0160] C) at least one pyridine azomethine insecticide selected from pymetrozine and pyrifluquinazon or its agrochemically acceptable salts, esters and derivatives, present in the range of 0.1-90% by weight of the composition; and D) one or more agrochemically acceptable excipients.

[0161] In another embodiment of the present invention, a stable synergistic insecticidal composition comprising:

[0162] A) compound of Formula I, chemically known as A-[methyloxido[l-[6-(trifluoromethyl)-3- pyridinyl]ethyl]-X4-sulfanylidene]cyanamide or its agrochemically acceptable salts, esters and derivatives, present in the range of 0.1-90% by weight of the composition

[0163] B) Compound of Formula II, chemically known as 4-bromo-2-(4-chlorophenyl)-l-(ethoxymethyl)-5-(trifluoromethyl)-lH-pyrrole-3-carbonitrile or its agrochemically acceptable salts, esters and derivatives, present in the range of 0.1-90% by weight of the composition;

[0164] C) at least one pyridine azomethine insecticide selected from pymetrozine and pyrifluquinazon or its agrochemically acceptable salts, esters and derivatives, present in the range of 0.1-90% by weight of the composition; and

[0165] D) at least one or more additives selected from Silwet Power, tallow amine ethoxylate, ammonium sulphate, and Epoxide soybean oil either alone or in combination thereof, present in the range of 0.01 - 20% by weight of the composition.

[0166] In another embodiment of the present invention, a stable synergistic insecticidal composition comprising:

[0167] A) compound of Formula I, chemically known as A-[methyloxido[l-[6-(trifluoromethyl)-3- pyridinyl]ethyl]-X4-sulfanylidene]cyanamide or its agrochemically acceptable salts, esters and derivatives, present in the range of 0.1-90% by weight of the composition

[0168] B) Compound of Formula II, chemically known as 4-bromo-2-(4-chlorophenyl)-l-(ethoxymethyl)-5-(trifluoromethyl)-lH-pyrrole-3-carbonitrile or its agrochemically acceptable salts, esters and derivatives, present in the range of 0.1-90% by weight of the composition;

[0169] C) at least one pyridine azomethine insecticide selected from pymetrozine and pyrifluquinazon or its agrochemically acceptable salts, esters and derivatives, present in the range of 0.1-90% by weight of the composition;

[0170] D) at least one or more additives selected from Silwet Power, tallow amine ethoxylate, ammonium sulphate, and Epoxide soybean oil either alone or in combination thereof, present in the range of 0.01 - 20% by weight of the composition; and

[0171] E) one or more agrochemically acceptable excipients.

[0172] In another embodiment of the present invention, a stable synergistic insecticidal composition comprising: A) Compound of Formula I, chemically known as A-[methyloxido[l-[6-(trifluoromethyl)-3- pyridinyl]ethyl]-X4-sulfanylidene]cyanamide or its agrochemically acceptable salts, esters and derivatives, present in the range of 0.1-90% by weight of the composition

[0173] B) Compound of Formula II, chemically known as 4-bromo-2-(4-chlorophenyl)-l-(ethoxymethyl)-5-(trifluoromethyl)-lH-pyrrole-3-carbonitrile or its agrochemically acceptable salts, esters and derivatives, present in the range of 0.1-90% by weight of the composition and

[0174] C) Pymetrozine or its agrochemically acceptable salts, esters and derivatives, , present in the range of 0.1-90% by weight of the composition.

[0175] In another embodiment of the present invention, a stable synergistic insecticidal composition comprising:

[0176] A) compound of Formula I, chemically known as A-[methyloxido[l-[6-(trifluoromethyl)-3- pyridinyl]ethyl]-X4-sulfanylidene]cyanamide or its agrochemically acceptable salts, esters and derivatives, present in the range of 0.1-90% by weight of the composition;

[0177] B) Compound of Formula II, chemically known as 4-bromo-2-(4-chlorophenyl)-l-(ethoxymethyl)-5-(trifluoromethyl)-lH-pyrrole-3-carbonitrile or its agrochemically acceptable salts, esters and derivatives, present in the range of 0.1-90% by weight of the composition;

[0178] C) Pymetrozine or its agrochemically acceptable salts, esters and derivatives, , present in the range of 0.1-90% by weight of the composition; and

[0179] D) one or more agrochemically acceptable excipients.

[0180] In another embodiment of the present invention, a stable synergistic insecticidal composition comprising:

[0181] A) compound of Formula I, chemically known as A-[methyloxido[l-[6-(trifluoromethyl)-3- pyridinyl]ethyl]-X4-sulfanylidene]cyanamide or its agrochemically acceptable salts, esters and derivatives, present in the range of 0.1-90% by weight of the composition

[0182] B) Compound of Formula II, chemically known as 4-bromo-2-(4-chlorophenyl)-l-(ethoxymethyl)-5-(trifluoromethyl)-lH-pyrrole-3-carbonitrile or its agrochemically acceptable salts, esters and derivatives, present in the range of 0.1-90% by weight of the composition;

[0183] C) Pymetrozine or its agrochemically acceptable salts, esters and derivatives, , present in the range of 0.1-90% by weight of the composition; D) at least one or more additives selected from Silwet Power, tallow amine ethoxylate, ammonium sulphate, and Epoxide soybean oil either alone or in combination thereof, present in the range of 0.01 - 20% by weight of the composition; and

[0184] E) one or more agrochemically acceptable excipients.

[0185] In another embodiment, the present invention provides a process for preparation of the stable synergistic insecticidal composition comprising:

[0186] A) compound of Formula I, chemically known as A-[methyloxido[l-[6-(trifluoromethyl)-3- pyridinyl]ethyl]-X4-sulfanylidene]cyanamide or its agrochemically acceptable salts, esters and derivatives;

[0187] B) Compound of Formula II, chemically known as 4-bromo-2-(4-chlorophenyl)-l-(ethoxymethyl)-5-(trifluoromethyl)-lH-pyrrole-3-carbonitrile or its agrochemically acceptable salts, esters and derivatives; and

[0188] C) at least one pyridine azomethine insecticide selected from pymetrozine and pyrifluquinazon or its agrochemically acceptable salts, esters and derivatives

[0189] In accordance with an embodiment of the present invention, there is provided a stable synergistic insecticidal composition comprising active ingredients present in the weight % range as given below:

[0190] In another embodiment of the present invention, the stable synergistic insecticidal composition of the present invention further comprises one or more agrochemically acceptable excipients including but not limited to the group comprising surfactant(s), dispersing agent(s), co-dispersant, anti-freezing agent(s), emulsifier(s)( (anionic and non-ionic), anti-foaming agent / defoamer(s), wetting agent(s), antimicrobial / anti-bacterial agent(s), anti-caking agent , thickening agent / thickener(s), quick coating agent(s) or sticking agentsZsticker(s), spreader(s), binder(s), pH-adjusting agent(s), anti-caking agent(s), adjuvant(s), filler(s) / suspension aid(s), colorant(s), carrier(s), buffering agent(s), polymer(s)rheology modifier(s), solvent(s), co-solvent(s) , biocide or a combination thereof. Additional components may also be included, e.g., protective colloids, carriers, adhesives, thixotropic agents, penetration agents, stabilisers, sequestering agents. More generally, the active materials can be combined with any solid or liquid carrier / additive, which complies with usual formulation techniques.

[0191] An adjuvant used in the present Invention is any material that is added to an agrochemical formulation to enhance or modify the performance of the formulation. An adjuvants used in the present invention to make it a safer to ecological environmental, having low toxicity and having no phytotoxicity effects on any part of the plant.

[0192] Examples of surfactant(s) and / or dispersing agent and / or co-dispersant used herein include but not limited polymeric anionic dispersant, polyarylphenyl ether phosphate, tristyryl phenol ethoxylate, Polymethyl methacrylate-polyethylene glycol graft copolymer, acrylate copolymer, acrylic copolymer, polymeric dispersant, Calcium salt of alkyl benzene sulphonate, Non-ionic surfactant, polyalkoxylated butyl ether, acrylic graft copolymer, Sodium methyl oleoyl taurate , non-ionic proprietary surfactant, Methyl naphthalene sulfonic acid, polymer with formaldehyde, sodium salt, ethoxylated tristryl phenol Sulphate, alkyl naphthalene formaldehyde condensate , naphthalene sulfonic acid, phenol sulfonic acid-formaldehyde polycondensation as sodium salt, sodium salt condensate with formaldehyde, ethoxylated oleyl cetyl alcohol, Sodium Alkyl Naphthalene Sulfonate Blend, polyalkelene glycol ether, Sodium Isopropyl Naphthalene Sulfonate, Dialkyl naphthalene sulphonate sodium salt, Naphthalene Sulphonic Acid, Formaldehyde, Acrylate graft Copolymer, Ethoxylated fatty glyceride , Ethoxylated Polyarylphenol Phosphate Ester, Lignosulfonic Acid, Sodium Salt, Sulfo methylated, ethoxylated fatty alcohol, methyl naphthalene sulfonic acid, polymer with formaldehyde sodium salt, Sodium Alkylnaphthalene Sulfonate Formaldehyde Condensate, Sodium polymethyl methacrylate, sodium polyacrylate, alkyl naphthalene sulfonate formaldehyde condensate or its sodium salt , Sodium Naphthalene Sulfonate formaldehyde condensate, sodium lignosulphonate, calcium lignosulphonate, Sodium Alkyl Naphthalene Sulfonate, Naphthalene Sulphonic Acid, Formaldehyde , alkylphenol polyoxyethylene ether, sodium salt of naphthalene sulfonate condensate, alkyl naphthalene sulfonate condensate blend, polymeric surfactant, sodium salt of alkyl naphthalene sulfonate, sodium salt of methyl naphthalene sulfonate, polycarboxylate, naphthalene sulfonic acid-branched and linear derivative sodium salts, fatty alcohol polyoxyethylene ether, alcohol polyglycol ether, non-aqueous dispersant - non-ionic polymeric surfactant, aqueous dispersant - polymeric amphoteric aqueous dispersant or mixtures thereof and present in the range of 0.1-20% by weight of the composition.

[0193] Examples of wetting agent used herein include but not limited to tristyrylphenol ethoxylate non-ionic emulsifier, polyalkoxylated butyl ether, mixture of non-ionic surfactants, Blend of Anionic and Non-ionic, alkoxylated alcohol, block copolymer, alcohol polyglycol ether, alkyl olefin sulphates, dioctyl sulpho succinate, alkyl naphthalene sulphate , Di-isopropyl Napthalene sulphonate, Benzenesulfonic acid, Hydroxy polymer with formaldehyde, Phenol and Urea sodium salt, Polyalkoxy ethers, alkyl phenol ethoxylates, tri- styrenated phenol ethoxylate, EO / PO block co-polymers, butyl polyalkylene oxide block copolymer, sodium lauryl sulphate, sodium sulphates or mixtures thereof and present in the range of 0.1-20% by weight of the total composition.

[0194] Examples of defoamer or antifoaming agent used herein include but not limited to silicon emulsion based anti-foam agents, Siloxane polyalkyleneoxide, Polydimethylsiloxane, trisiloxane ethoxylates, silicone oil, silicone compound, C10~C20 saturated fat acid compounds or C8~C10 aliphatic alcohols compound, vegetable oil based antifoam, tallow based fatty acids, polyalkyleneoxide polydimethylsiloxane emulsion and mixtures thereof and present in the range of 0.01-5.0 % by weight of the composition.

[0195] Examples of anti-freezing agent used herein include but not limited to glycol, propylene glycol, mono ethylene glycol, glycerine, diethylene glycol, sorbitol, urea, mannitol, polyethylene glycol or mixtures thereof and present in the range of 1.0-20% by weight of the composition.

[0196] Examples of fillers used herein include but not limited to silicon dioxide, china-clay, kaolin, starch, bentonite, precipitated silica, fumed silica, lactose monohydrate, talcum powder, lactose, ammonium sulphate, water, sodium Sulphate, magnesium sulphate, sodium citrate, sodium chloride, potassium chloride and mixtures thereof and present in the range of 0.1-60 % by weight of the composition.

[0197] Examples of anti-caking agent used herein include but not limited to group of talc, hydrous magnesium silicate, magnesium carbonate, calcium carbonate, precipitate silica, silica powder, hydrophobic fumed silica and mixtures thereof and present in the range of 0.1-10% by weight of the composition.

[0198] Examples of carrier used herein include but not limited to silicon dioxide, china clay, kaolin, starch, bentonite, precipitated silica, silica powder, fumed silica, ppt silica powder, lactose monohydrate, talcum powder, lactose, ammonium sulpha or mixture thereof and present in the range of 0.1 -45 % by weight of the composition.

[0199] Examples of biocide or anti -microbial agent used herein include but not limited to 1, 2,- Benzisothiazolin - 3-one, blends of 1,2,- benzisothiazolin-3-one and 2-methyl-4-isothiazolin-3-one, 5-chloro-2-methyl-4- isothiazolin-3-one, blends of 5-chloro-2-methyl-4-isothiazolin-3-one and 2-methyl-4-isothiazolin-3-one, zinc l-hydroxy-2(lH)-pyridinethione, blends of zinc l-hydroxy-2(lH)-pyridinethione and zinc oxide, and 2-n-octyl-4- isothiazolin-3-one or mixture thereof and present in the range of 0.01 to 10 % by weight of the composition.

[0200] Examples of rheology modifier or thickeners or thickening agents used herein include but not limited to polysaccharides, carboxymethyl cellulose, bentonite clay, aluminium magnesium silicate, hydroxy propyl cellulose, xanthan gum, gum arabic, Silica powder, gaur gum, carbomer, chitosan, precipitated silica or mixtures thereof and present in the range of 0.01-5.0 % by weight of the composition.

[0201] Examples of emulsifier(s) used herein include but not limited to araliphatic or aliphatic non-ionic oil emulsifier-ethoxylated sorbitol hexaester derived from oleic acid, emulsifier such as ethoxylated mono-, di- and trialkylphenols, ethoxylates of long-chain alcohols and polyethylene oxide / polypropylene oxide homo- and copolymers, EO / PO block copolymers, Polymeric emulsifier (Nonionic polyalkylene oxide block copolymer), Ethoxylates of long -chain alkanols, Castor oil ethoxylate , ethoxylated monoalkylphenol, ethoxilates of cetyl alcohol and / or stearyl alcohol ; Tristyrylphenol ethoxylate-20 mole, Ethoxylated Tristyrylphenol ,and Anionic emulsifier such as alkali metal and ammonium salts of alkyl sulfates, of hemisulfates of ethoxylated alkanols and ethoxylated alkylphenols, alkylsulfonic acids, bis(phenylsulfonic acid) ethers and their alkali metal or ammonium salts, sodiumlaurylsulfate, sodium (cetyl / stearyl) sulfate or mixture thereof and present in the range of 0.01 -20 % by weight of the composition.

[0202] Examples of solvent(s) and co-solvent(s) used herein include but not limited to polar and non-polar solvent from the group comprising heavy aromatic hydrocarbon, N methyl pyrollidone (NMP) , Solvent Naphtha (Solvent C-9), Di methyl sulfoxide (DMSO), Dimethylformamide (DMF), N- alcohol, 2-ethyl hexanol , alkyl amide, vegetable oil, mineral oil, distilled water, aromatic solvents, water or mixtures thereof and present in the range of 1.0 to 20% by weight of the composition. Examples of colouring pigment(s) / dye(s) used herein include but not limited to red dye FGR03, Permanent Rubin L5-B-01, pigment blue 15:4, pigment blue 15:3, pigment blue 15:2, pigment blue 15:1 , pigment blue 80, pigment yellow 1 , pigment yellow 13, pigment red 112, pigment red 48:2, pigment red 48:1 , pigment red 57: 1 , pigment red 53:1 , pigment orange 43, pigment orange 34, pigment orange 5, pigment green 36, pigment green 7, pigment white 6, pigment brown 25, basic violet 10, basic violet 49, violet 23, acid red 51 , acid red 52, acid red 14, acid blue 9, acid yellow 23, basic red 10, basic red 108 or mixtures thereof and present in the range of 0.01- 10.0 % by weight of the composition.

[0203] Examples of polymer(s) used herein include but not limited to isocyanate, polyisocyanate used is toluene - 2, 4-diisocyanate (TDI), diethylenetriamine (DETA), ethylene diamine (EDA), triethylenetetramine (TETA), and / or hexamethylene diamine (HMDA), diethanolglycine sodium salt, ethanoldiglycine disodium salt, hydroxymonocarboxylic acid compounds, hydroxydicarboxylic acid compounds, tetrasodium N,N-bis(carboxylatomethyl)-L-glutamate (GLDA), methylene diisocyanate (MDI), and / or low molecular weight polydiisocynates or mixtures thereof and present in the range of 0.01- 5.0 % by weight of the composition.

[0204] Examples of binder(s) used herein include but not limited to polyvinylpyrrolidone, polyvinyl alcohol, methyl cellulose, and carboxymethyl cellulose, polyisocyanate, polyterpene resin or mixtures thereof and present in the range of 0.01- 40 % by weight of the composition.

[0205] In yet another embodiment of the present invention, the present stable synergistic insecticidal composition can be formulated as one or more of Capsule suspension (CS), Dispersible concentrate (DC), Dustable powder (DP), Powder for dry seed treatment (DS), Emulsifiable concentrate (EC), Emulsifiable granule (EG), Emulsion water-in-oil (EO), Emulsifiable powder (EP), Emulsion for seed treatment (ES), Emulsion oil-in-water (EW), Flowable concentrate for seed treatment (FS), Granules (GR), Micro-emulsion (ME), Oil-dispersion (OD), Oil miscible flowable concentrate (OF), Oil miscible liquid (OL), Oil dispersible powder (OP), Suspension concentrate (SC), Suspension concentrate for direct application (SD), Suspo- emulsion (SE), Water soluble granule (SG), Soluble concentrate (SL), Spreading oil (SO), Water soluble powder (SP), Water soluble tablet (ST), Ultra-low volume (ULV) suspension, Tablet (TB), Ultra-low volume (ULV) liquid, Water dispersible granules (WG), Wettable powder (WP), Water dispersible powder for slurry seed treatment (WS), Water dispersible tablet (WT), a mixed formulation of CS and SC (ZC) or a mixed formulation of CS and SE (ZE) or a mixed formulation of CS and EW (ZW).

[0206] In yet another embodiment of the present invention, the invention further provides the process for preparation of the said insecticidal composition, wherein the said composition can be one or more of Capsule suspension (CS), Dispersible concentrate (DC), Dustable powder (DP), Powder for dry seed treatment (DS), Emulsifiable concentrate (EC), Emulsifiable granule (EG), Emulsion water-in-oil (EO), Emulsifiable powder (EP), Emulsion for seed treatment (ES), Emulsion oil-in-water (EW), Flowable concentrate for seed treatment (FS), Granules (GR), Micro-emulsion (ME), Oil-dispersion (OD), Oil miscible flowable concentrate (OF), Oil miscible liquid (OL), Oil dispersible powder (OP), Suspension concentrate (SC), Suspension concentrate for direct application (SD), Suspo-emulsion (SE), Water soluble granule (SG), Soluble concentrate (SL), Spreading oil (SO), Water soluble powder (SP), Water soluble tablet (ST), Ultra-low volume (ULV) suspension, Tablet (TB), Ultra-low volume (ULV) liquid, Water dispersible granules (WG), Wettable powder (WP), Water dispersible powder for slurry seed treatment (WS), Water dispersible tablet (WT), a mixed formulation of CS and SC (ZC) or a mixed formulation of CS and SE (ZE) or a mixed formulation of CS and EW (ZW).

[0207] In further embodiment, depending on the formulation type, they comprise one or more liquid or solid carriers, appropriate surfactants (such as dispersants, protective colloids, emulsifiers, wetting agents and tackifiers), and appropriate further excipients which are customary for formulating agrochemical composition. Further excipients include e.g. organic and inorganic thickeners, bactericides, antifreeze agents, antifoams, colorants and, for seed formulations, adhesives.

[0208] Suitable carriers include liquid and solid carriers. Liquid carriers include e.g. non-aqueous solvents such as cyclic and aromatic hydrocarbons, e.g. paraffins, tetrahydronaphthalene, alkylated naphthalenes and their derivatives, alkylated benzenes and their derivatives, alcohols such as methanol, ethanol, propanol, butanol and cyclohexanol, ketones such as cyclohexanone, strongly polar solvents, e.g. amines such as N- methylpyrrolidone, and water as well as mixtures thereof. Solid carriers include e.g. mineral earths such as silicas, silica gels, silicates, talc, kaolin, limestone, lime, chalk, bole, loess, clay, dolomite, diatomaceous earth, calcium sulfate, magnesium sulfate, magnesium oxide, ground synthetic materials, fertilizers such as ammonium sulfate, ammonium phosphate, ammonium nitrate, ureas, and products of vegetable origin such as cereal meal, tree bark meal, wood meal and nutshell meal, cellulose powders, or other solid carriers.

[0209] In one embodiment, additives such as silwet power or silwet power super-wetter is an organosilicone based powder adjuvant that can enhance the water absorption efficiency of hard-to-wet soils by increasing their water infiltration, drainage, water retention and hydrophilicity; tallow amine ethoxylate increases the biocompatibility in environmental applications and help in the interactions of active ingredients; ammonium sulphate help is resistant to leaching and helps the crop to utilize nitrogen efficiently; and epoxide soybean oil provides increased active ingredient uptake and improved rain fastness to the composition. The said additives are stable and hygroscopic resulting in an efficient uptake and functioning.

[0210] In one embodiment, silwet power has superspreading ability, it significantly lowers the surface tension of spray solutions, allowing them to spread uniformly across plant surfaces, including waxy or hard-to-wet leaves. This enhances the penetration and absorption of insecticides, leading to improved efficacy. Silwet Power is especially effective in low-volume spray applications and helps increase rainfastness and reduce runoff. Its use supports more efficient pesticide delivery, often allowing for reduced application rates.

[0211] In one embodiment, the inclusion of both Silwet Power super-wetter and tallow amine ethoxylate in a formulation significantly enhances its surface activity and delivery efficiency. Silwet Power, a trisiloxane- based super-spreader, dramatically reduces surface tension, enabling rapid and uniform spreading of the solution across plant surfaces, even on waxy or water-repellent leaves. In synergy, tallow amine ethoxylate, a non-ionic surfactant, acts as a powerful wetting and penetration agent, improving the absorption of active ingredients into plant tissues. This combination ensures maximum bioavailability and performance of agrochemical actives

[0212] In one embodiment, ammonium sulphate particularly as a water conditioner and adjuvant. It helps improve the efficacy of pesticides, by binding with hard water cations such as calcium and magnesium that would otherwise reduce pesticide absorption and activity. By preventing these ions from interacting with the active ingredient, ammonium sulphate enhances uptake into plant tissues. It may also act as a nitrogen source, supporting plant growth.

[0213] In one embodiment, Epoxide soybean oil, a bio-based plasticizer and solvent, improves formulation compatibility, reduces phytotoxicity, and enhances the dispersion of active compounds. Derived from renewable sources, both additives support sustainable agriculture by offering low toxicity, biodegradability, and improved formulation efficiency without compromising efficacy.

[0214] In one embodiment, Silwet Power, tallow amine ethoxylate, ammonium sulphate, and epoxidie soybean oil are additives used individually or in combination to enhance the performance of agrochemical formulations. Silwet Power, a superspreading organosilicone surfactant, reduces surface tension and improves leaf coverage and penetration of active ingredients. Tallow amine ethoxylates, as non-ionic surfactants, aid in emulsification and enhance pesticide uptake. Ammonium sulphate serves as a water conditioner, preventing hard water ions from reducing pesticide efficacy, while also acting as a nitrogen source. Epoxide soybean oil, a biodegradable solvent and plasticizer, improves formulation stability, compatibility, and reduces phyto toxicity. Used alone or synergistically, these additives optimize spray performance, improve bioavailability of actives, and support sustainable and effective crop protection. In one embodiment, additives such as silwet power or silwet power super-wetter, tallow amine ethoxylate, ammonium sulphate, and epoxide soybean oil either alone or in combination thereof, present in the range of 0.01 - 20% by weight of the composition.

[0215] In an embodiment, each individual row appearing in the table below represents the combinations in an embodiment of the present invention.

[0216] Compound of formula I, reffered herein pertains to A-[methyloxido[l-[6-(trifluoromethyl)-3- pyridinyl]ethyl]-X4-sulfanylidene]cyanamide or its agrochemically acceptable salts, esters and derivatives.

[0217] Compound of formula II, referred herein pertains to 4-bromo-2-(4-chlorophenyl)-l-(ethoxymethyl)-5- (trifluoromethyl)-lH-pyrrole-3-carbonitrile or its agrochemically acceptable salts, esters and derivatives.

[0218] In one aspect / another embodiment, the present stable synergistic insecticidal composition of the present invention can be applied to a plant / crop / soil by spraying, rubbing, atomizing, irrigating, evaporating, dusting, fogging, broadcasting, pouring, mist blowing, soil mixing, foaming, painting, spreading-on, drenching, dipping or drip irrigation etc.

[0219] In yet another embodiment of the present invention, the present stable synergistic insecticidal composition can be applied to various crops and plants including but not limited to Chilli, Cabbage, Okra (Bhindi), Cotton, Cumin, Onion, Mango, Brinjal, Rice, Paddy, Soybean, Cotton, Cruciferous vegetables.

[0220] In yet another embodiment of the present invention, the present insecticidal composition provides synergistic and effective control against sucking complex pests including thrips, whitefly (bemmissia tabaci), aphids (aphis gossypi), jassids (amarasca bigutella), diamond back moth (plutella xylostella), hoppers, mites (polyphagotarsonemus latus), bollworms, shoot, stem, fruit borer, brown plant hopper (nilaparvatha lugens), whitebacked plant hopper (sogatella furcifera), girdle beetle, semi looper and tobacco caterpillar, cotton mealy bug (phenococcus spp.) etc.

[0221] In yet another embodiment, the composition according to the invention can be applied to any and all developmental stages of insect pests, such as egg, nymph, larva, pupa, and adult. The insect pests may be controlled by contacting the target insect pest, habitat, breeding ground or its locus with a bioactive amount of the novel and inventive composition of the present invention. In yet another embodiment, the present stable synergistic insecticidal composition of the present invention can be applied to a plant / crop / soil by spraying, rubbing, atomizing, irrigating, evaporating, dusting, fogging, broadcasting, pouring, mist blowing, soil mixing, foaming, painting, spreading -on, drenching, dipping or drip irrigation, etc.

[0222] In yet another embodiment, the composition of the present invention can also comprise or may be applied together and / or sequentially with further active compounds. These further compounds can be selected from fertilizers or micronutrient donors or microorganisms or other preparations that influence plant growth, such as inoculants (e.g. a strain of nitrogen-fixing bacteria), and plant inducers.

[0223] Through the insecticidal composition of present invention, the number of applications to control wide range of pests appearing at the same time is minimised. The composition of present invention is highly safe to the user and to the environment. The composition offers the user a single homogenous application eliminating the need for tank mix. The composition also is cost-effective as it provides much greater simultaneous control and can be used in a variety of crops with a broader spectrum of protection.

[0224] The novel composition of the present invention has very advantageous, curative, preventive and systemic insecticidal properties for protecting plants and crops.

[0225] The composition of the present invention also provides control of insect-pests’ preventatively or curatively by applying an effective amount of the composition either pre -or post-infection.

[0226] In an embodiment, the kit-of-parts comprises an instructions manual, said instructions manual comprising instructions directing a user to ad-mix the components before being used.

[0227] Thus, before describing the present invention in detail, it is to be understood that this invention is not limited to particularly exemplified systems or process parameters that may of course, vary. It is also to be understood that the terminology used herein is for the purpose of describing particular embodiments of the invention only and is not intended to limit the scope of the invention in any manner. The use of examples anywhere in this specification including examples of any terms discussed herein is illustrative only, and in no way limits the scope and meaning of the invention or of any exemplified term. Likewise, the invention is not limited to various embodiments given in this specification. Unless otherwise defined, all technical and scientific terms used herein have the same meaning as commonly understood by one of ordinary skill in the art to which this invention pertains. In the case of conflict, the present document, including definitions will control. In one embodiment, the composition according to the present invention acts synergistically to control pests in various crops.

[0228] Representative examples of the present composition of this invention are provided below and are not to be construed as limiting in any manner: Compound of formula I, reffered herein pertains to 7V-[methyloxido[l-[6-(trifluoromethyl)-3- pyridinyl]ethyl]-X4-sulfanylidene]cyanamide or its agrochemically acceptable salts, esters and derivatives.

[0229] Compound of formula II, referred herein pertains to 4-bromo-2-(4-chlorophenyl)-l-(ethoxymethyl)-5- (trifluoromethyl)-lH-pyrrole-3-carbonitrile or its agrochemically acceptable salts, esters and derivatives.

[0230] EXAMPLES: GENERAL RECIPE OF COMPOSITION OF PRESENT INVENTION:

[0231] Example A: Compound of formula I 8.7% + Compound of formula II 9.6% + Pymetrozine 14.7% SC

[0232] MANUFACTURING PROCESS: Pre- mixing:

[0233] 1. Charged D.M water into a clean reactor and stirred then added propylene glycol, Sodium Isopropyl Naphthalene Sulfonate, Sodium Alkylnaphthalene Sulfonate Formaldehyde Condensate, Acrylate graft Copolymer, Poly dimethyl siloxane, additives and l,2-Benzisothiazolin-3-one, further allowed it to mix well to make a homogeneous solution, 2. To the above solution further added Compound of formula I technical, Compound of formula Iltechnical and Pymetrozine technical and mixed well to form a homogeneous slurry.

[0234] Wet-milling process:

[0235] 1. Allowed to pass the above prepared premix through bead mill at 400 to 500 Ltr / hr feed rate so as get a desired particle size. 2. The grinded material was collected in post mixer. Post- Mixing:

[0236] 1. The milled slurry was collected into the post mixer and to xantham gum solution was added.

[0237] 2. Mixed well till the slurry attains right viscosity

[0238] 3. Packed the formulation into HDPE bottles.

[0239] STABILITY DATA: Compound of formula 18.7% + Compound of formula II 9.6% + Pymetrozine 14.7% SC

[0240] Example B: Compound of formula I 8.7% + Compound of formula II 9.6% + Pymetrozine 14.7% WP

[0241] FORMULATION PROCESS:

[0242] 1. Mixed all raw materials and technicals and grind in air jet mill.

[0243] 2. Checked the particle size after grinding, to make sure that it is less than 10 microns (D90). 3. Post blended the grinded powder and mixed well.

[0244] STABILITY DATA: Compound of formula 18.7% + Compound of formula II 9.6% + Pymetrozine 14.7%

[0245] WP

[0246] Example C: Compound of formula I 8.7% + Compound of formula II 9.6% + Pymetrozine 14.7% WG MANUFACTURING PROCESS:

[0247] 1. Took china clay in the ribbon blender for mixing. 2. To this above, added Silica powder, Acrylate Copolymer, Sodium Isopropyl Naphthalene Sulfonate, Naphthalene Sulphonic Acid, Formaldehyde, Sodium Methyl Oleoyl Taurate, polymeric dispersant, Lactose monohydrate, additives, Compound of formula I technical, Compound of formula II technical and Pymetrozine technical and mixed well.

[0248] 3. Continued to mix this till the material is completely homogenised.

[0249] 4. Allowed to pass the premix through the Airjet mill at 6 to 7 kg / cm2 of grinding pressure and 100 to 150 kg / hr feeding rate so as get a particle size of D90 less than 10 microns.

[0250] 5. The grinded material was collected in post blender.

[0251] Extrusion process

[0252] 1. Into the post blender the solution of water and Poly dimethylsiloxane emulsion added by means of spraying and dough was prepared.

[0253] 2. This dough was mixed well to get a well hydrated dough for extrusion.

[0254] 3. This dough then allowed to pass through the screw valve fitted with post blender and then passed through basket extruder.

[0255] Drying Process

[0256] 1. These wet extruded granules then passed through VFBG (vibro-fluid bed drier) which was brought to a consistent temperature of 50°C prior to drying of wet granules.

[0257] 2. These granules are checked for moisture content which should not more than 3%. Once the parameter got set then the process continued.

[0258] Sieving and packing.

[0259] The dried granule was passed through vibro sieve machine to separate any lumps or dust and desired size granules were collected and packed.

[0260] STABILITY DATA: Compound of formula 18.7% + Compound of formula II 9.6% + Pymetrozine 14.7% WG

[0261] Evaluation of synergistic effect of insecticidal composition of the present invention

[0262] A synergistic effect of two or more products exists whenever the action of an active ingredient combination is greater than the sum of the actions of the individual components. Synergism was calculated by using Colby’s method (Weeds, vol. 15 No. 1 (Jan 1967), pp. 20-2.

[0263] The synergistic action expected for a given combination of two active components can be calculated as follows:

[0264] XY

[0265] E = (X + Y) -

[0266] 100

[0267] The synergistic action expected for a given combination of three active components can be calculated as follows:

[0268] (XY+YZ+XZ) (XYZ)

[0269] E = (X + Y + Z) - + -

[0270] 100 10000

[0271] Where:

[0272] E represents expected percentage of pesticidal control for the combination of the two or three actives ingredients at defined doses (for example equal to x, y and z, respectively).

[0273] X is the percentage of pesticidal control observed by the compound (Compound of formula I) at a defined dose (equal to x).

[0274] Y is the percentage of pesticidal control observed by the compound (Compound of formula II) at a defined dose (equal to y).

[0275] Z is the percentage of pesticidal control observed by the compound (Pymetrozine) at a defined dose (equal to z).

[0276] When the percentage of pesticidal control observed for the combination is greater than the expected percentage, there is a synergism effect.

[0277] Observed control (%)

[0278] Ratio = -

[0279] Expected control (%) Ratio of O / E > 1, synergism observed

[0280] The present invention is illustrated by way of examples, the examples are meant for illustrative purposes and should not be construed as limiting. Experiment for Synergistic activity of combination product of present invention:

[0281] Example 1- Details of experiment on cotton crop:

[0282] Field experiment for synergistic activity of Compound of formula I, Compound of formula II& Pymetrozine for the control of Bollworms and sucking pests in cotton crop was conducted.

[0283] To evaluate the synergistic effect, cotton (Variety: Suraj) crop was sown in 4.5 m x 3.6 m plots maintaining 90 cm x 60 cm plant distance with three replications and in Randomized Block Design (RBD). The treatments were applied as foliar spray in the form of SC formulation @ 1000 ml / ha. Each active component was applied twice in different ternary and binary compositions at vegetative and reproductive stages of the crop, respectively. Solo compositions were also taken for comparison. The treatment details are as under:

[0284] The treatments T1 to T28 were used as foliar application whereas no treatment was done for T29 control treatment. Two applications at vegetative and reproductive stages were done of all treatments on the appearance of Insect at experimental plots. Observations for Bollworm complex was recorded at before spray, 7 days & 14 days after 2ndapplication by observing 5 random plants per plot and number of bollworms per plant was calculated. Among the sucking pests, the observations for whitefly (Bemisia labaci) population at before spray, 7 & 14 days after 1stand 2ndapplication were recorded on 3 leaves of 5 randomly selected plants per plot. The per cent reduction in bollworm complex and whitefly population was calculated over control. Based on the per cent reduction at 14 days after second spray in bollworm complex and whitefly population the Expected control was calculated and compared with Observed control.

[0285] The results of the trial have been presented here under in Table 1A.

[0286] Table 1A: Synergistic effect of composition of the present invention (Compound of formula I + Compound of formula 11+ Pymetrozine) against Bollworms and whitefly in cotton crop

[0287] It is clearly evident from the data shown in above Table 1A for per cent boll worm control and per cent whitefly pest control in cotton crop that the insecticidal composition of the present invention comprising Compound of formula I, Compound of formula II, Pymetrozine i.e. T1 to T4 are synergistic for both bollworm complex and whitefly control with > 1 Colby’s Ratio. The binary compositions of two insecticides (Compound of formula I + Compound of formula II, Compound of formula I + Pymetrozine and Compound of formula 11+ Pymetrozine) T5 to T16 are compatible but no synergistic effect was observed for the control of boll worm and whitefly.

[0288] Experiment for Bio-efficacy evaluation of composition of the present invention: For the ternary and binary compositions, based on Compound of formula I, Compound of formula Iland Pymetrozine evaluation under field conditions, the basic test composition as Compound of formula I 8.7% + Compound of formula 119.6% + Pymetrozine 14.7% SC was manufactured. For ternary composition, Compound of formula I 8.7% + Compound of formula 119.6% + Pymetrozine 14.7% SC was used and for binary compositions, Compound of formula I 8.7% + Compound of formula 119.6% SC, Compound of formula I 8.7% + Pymetrozine 14.7% SC, Compound of formula 119.6% + Pymetrozine 14.7% SC were used. The solo formulations of Compound of formula I 8.7% SC, Compound of formula 119.6% SC and Pymetrozine 14.7% SC were also used for comparison along with control treatment. The formulation of Compound of formula I 21.8 % w / w SC, and Compound of formula II240 g / L SC available in the market were used for comparison.

[0289] Example 2: Evaluation of the composition of the present invention on cotton

[0290] The stable synergistic insecticidal composition of the present invention Compound of formula I 8.7% + Compound of formula 119.6% + Pymetrozine 14.7% SC was evaluated on cotton crop variety Suraj. The crop sowing was done in Randomized Block Design (RBD) with three replications maintaining a distance of 90 cm x 60 cm between plants and rows.

[0291] The observations were recorded for the following objectives.

[0292] Objectives:

[0293] 1. Bio-efficacy evaluation against Bollworm complex on cotton crop.

[0294] 2. Bio-efficacy evaluation against whitefly on cotton crop.

[0295] 3. Bio-efficacy evaluation based on per cent reduction in Bollworm complex over control.

[0296] 4. Bio-efficacy evaluation based on percent reduction in whitefly population over control.

[0297] 5. Bio-efficacy evaluation based on crop yield.

[0298] 6. Phytotoxicity evaluation on cotton crop.

[0299] Treatment details:

[0300] Methodology:

[0301] The treatments T1 to T17 and T19 were used as foliar application whereas no treatment was done for T18 i.e., control treatment. All treatments were applied at the time of initiation of pest in the experimental plots, one in vegetative and another application in reproductive stage of the crop. The observations for Bollworm complex were recorded at before spray, 7 days & 14 days after 2ndapplication by observing 5 random plants per plot and number of bollworms per plant was calculated. Among the sucking pests, the observations for whitefly (Bemisia tabaci) population at before spray, 7 & 14 days after 1stand 2ndapplication were recorded on 3 leaves of 5 randomly selected plants per plot. The per cent reduction in insect-pest’s population was also calculated over control. The crop yield was recorded at crop harvest. The observations for phytotoxicity on cotton crop at 1, 3, 7, 10 and 14 days after both applications were also recorded. Results are presented in Table 2 A, 2B, 2C and 2D.

[0302] Results:

[0303] Table 2A: Field bio-efficacy evaluation of Compound of formula I 8.7% + Compound of formula 119.6% + Pymetrozine 14.7% SC against bollworm complex in cotton crop

[0304]

[0305]

[0306] Figures in parentheses are sq. root transformed values; NS= Non significant

[0307] Table 2B: Field bio-efficacy evaluation of Compound of formula I 8.7% + Compound of formula 119.6% + Pymetrozine 14.7% SC against whitefly in cotton crop

[0308] Figures in parentheses are square root transformed values; NS= Non significant

[0309] Table 2C: Field bio-efficacy evaluation of Compound of formula 18.7% + Compound of formula 119.6% + Pymetrozine 14.7 % SC based on yield of cotton crop.

[0310]

[0311] Table 2D: Phytotoxicity evaluation of Compound of formula 18.7 % + Compound of formula 119.6% + Pymetrozine 14.7% SC on cotton crop

[0312] From the examples above, it is clearly seen that the stable synergistic insecticidal composition of the present invention is superior for controlling the Boll worm complex at 14 days after application (Table 2) and for controlling whitefly ( Bemis ia l abaci) at 7 & 14 days after both applications (Table 3) in cotton crop as compared to the other binary and solo composition applied at the same dosage and other products viz. Compound of formula I 21.8 % w / w SC, and Compound of formula II240 g / L SC available in the market. The yield of cotton crop also improved in the ternary composition of Compound of formula I 8.7% + Compound of formula 119.6% + Pymetrozine 14.7% SC as compared to binary and solo compositions (Table 4). The stable synergistic insecticidal composition of the present invention comprising Compound of formula I 8.7% + Compound of formula 119.6% + Pymetrozine 14.7% SC @ 750ml, 1000 ml, 1250 ml and 2000 ml / ha further showed no phytotoxicity in the cotton crop even after 1, 3, 7, 10 and 14 days after 1stspray (Table 5).

[0313] It is evident from the above data that the composition of the present invention i.e., Compound of formula I 8.7% + Compound of formula 119.6% + Pymetrozine 14.7% SC resulted in good control of Bollworm complex and whitefly in cotton with higher respective yields as compared to the reference standard products (binary compositions and solo products). Further, the composition of present invention is resulted synergistic.

[0314] From the above investigations, it will be observed that numerous modifications and variations can be effectuated without departing from the true spirit and scope of the novel concepts of the present invention. It is to be understood that no limitations with respect to the specific embodiments illustrated is intended or should be inferred. It should be understood that all such modifications and improvements have been deleted herein for the sake of conciseness and readability but are properly within the scope of the following claims.

[0315] In particular, it has now been found, surprisingly that, for example, the insecticidal activity of the composition of present invention, compared with the insecticidal activity of individual components, is synergistic. In fact, various advantageous properties associated with the compositions according to the invention, include but are not limited to: knock down effect on insect pests including sucking pests complex at all developmental stages of insects such as egg, nymph, larva, pupa, and adult, preventing discoloration of leaves of plants and crops, enhanced tenderness to plants and crops, preventing ageing of plants and crops and other advantages familiar to a person skilled in the art.

[0316] From the above investigations, it will be observed that numerous modifications and variations can be effectuated without departing from the true spirit and scope of the novel concepts of the present invention. It is to be understood that no limitations with respect to the specific embodiments illustrated is intended or should be inferred. It should be understood that all such modifications and improvements have been deleted herein for the sake of conciseness and readability but are properly within the scope of the following claims.

Claims

I CLAIM

1. . A stable synergistic insecticidal composition comprising:A) compound of Formula I, chemically known as A-[methyloxido[l-[6-(trifluoromethyl)-3- pyridinyl]ethyl]-X4-sulfanylidene]cyanamide or its agrochemically acceptable salts, esters and derivatives;B) compound of Formula II, chemically known as 4-bromo-2-(4-chlorophenyl)-l-(ethoxymethyl)-5-(trifluoromethyl)-lH-pyrrole-3-carbonitrile or its agrochemically acceptable salts, esters and derivatives; andC) at least one pyridine azomethine insecticide selected from pymetrozine and pyrifluquinazon or its agrochemically acceptable salts, esters and derivatives.

2. , The stable synergistic insecticidal composition as claimed in claim 1, comprising:A) compound of Formula I, chemically known as A-[methyloxido[l-[6-(trifluoromethyl)-3- pyridinyl]ethyl]-X4-sulfanylidene]cyanamide or its agrochemically acceptable salts, esters and derivatives, present in the range of 0.1-90% by weight of the compositionB) compound of Formula II, chemically known as 4-bromo-2-(4-chlorophenyl)-l-(ethoxymethyl)-5-(trifluoromethyl)-lH-pyrrole-3-carbonitrile or its agrochemically acceptable salts, esters and derivatives, present in the range of 0.1-90% by weight of the composition andC) at least one pyridine azomethine insecticide selected from pymetrozine and pyrifluquinazon or its agrochemically acceptable salts, esters and derivatives, , present in the range of 0.1 -90% by weight of the composition.

3. . A stable synergistic insecticidal composition, as claimed in claimed in claim 1 and 2, comprising:A) compound of Formula I, chemically known as A-[methyloxido[l-[6-(trifluoromethyl)-3- pyridinyl]ethyl]-X4-sulfanylidene]cyanamide or its agrochemically acceptable salts, esters and derivatives, present in the range of 0.1-90% by weight of the compositionB) compound of Formula II, chemically known as 4-bromo-2-(4-chlorophenyl)-l-(ethoxymethyl)-5-(trifluoromethyl)-lH-pyrrole-3-carbonitrile or its agrochemically acceptable salts, esters and derivatives, present in the range of 0.1-90% by weight of the composition andC) Pymetrozine or its agrochemically acceptable salts, esters and derivatives, , present in the range of 0.1-90% by weight of the composition.

4. . A stable synergistic insecticidal composition comprising:A) compound of Formula I, chemically known as A-[methyloxido[l-[6-(trifluoromethyl)-3- pyridinyl]ethyl]-X4-sulfanylidene]cyanamide or its agrochemically acceptable salts, esters and derivatives;B) Compound of Formula II, chemically known as 4-bromo-2-(4-chlorophenyl)-l-(ethoxymethyl)-5-(trifluoromethyl)-lH-pyrrole-3-carbonitrile or its agrochemically acceptable salts, esters and derivatives;C) at least one pyridine azomethine insecticide selected from pymetrozine and pyrifluquinazon or its agrochemically acceptable salts, esters and derivatives; andD) at least one or more additives.

5. . A stable synergistic insecticidal composition, as claimed in claimed in claim 4, comprising:A) compound of Formula I, chemically known as A-[methyloxido[l-[6-(trifluoromethyl)-3- pyridinyl]ethyl]-X4-sulfanylidene]cyanamide or its agrochemically acceptable salts, esters and derivatives;B) Compound of Formula II, chemically known as 4-bromo-2-(4-chlorophenyl)-l-(ethoxymethyl)-5-(trifluoromethyl)-lH-pyrrole-3-carbonitrile or its agrochemically acceptable salts, esters and derivatives;C) at least one pyridine azomethine insecticide selected from pymetrozine and pyrifluquinazon or its agrochemically acceptable salts, esters and derivatives; andD) at least one or more additive selected from Silwet Power, tallow amine ethoxylate, ammonium sulphate, and Epoxide soybean oil either alone or in combination thereof.

6. . A stable synergistic insecticidal composition, as claimed in claimed in claim 4 and 5, comprising:A) compound of Formula I, chemically known as A-[methyloxido[l-[6-(trifluoromethyl)-3- pyridinyl]ethyl]-X4-sulfanylidene]cyanamide or its agrochemically acceptable salts, esters and derivatives, present in the range of 0.1-90% by weight of the compositionB) Compound of Formula II, chemically known as 4-bromo-2-(4-chlorophenyl)-l-(ethoxymethyl)-5-(trifluoromethyl)-lH-pyrrole-3-carbonitrile or its agrochemically acceptable salts, esters and derivatives, present in the range of 0.1-90% by weight of the composition;C) at least one pyridine azomethine insecticide selected from pymetrozine and pyrifluquinazon or its agrochemically acceptable salts, esters and derivatives, present in the range of 0.1-90% by weight of the composition; andD) at least one or more additives selected from Silwet Power, tallow amine ethoxylate, ammonium sulphate, and Epoxide soybean oil either alone or in combination thereof, present in the range of 0.01 - 20% by weight of the composition.

7. . The stable synergistic insecticidal composition as claimed in claims 1-6, which further comprises one or more agrochemically acceptable excipients.

8. . The stable synergistic insecticidal composition as claimed in claim 7, wherein agrochemically acceptable excipients comprises surfactant(s), dispersing agent(s), co-dispersant, anti-freezing agent(s), emulsifier(s)( (anionic and non-ionic), anti-foaming agent / defoamer(s), wetting agent(s), biocide / antimicrobial / anti-bacterial agent(s), thickening agentZthickener(s), quick coating agent(s) or sticking agentsZsticker(s), spreader(s), binder(s), pH-adjusting agent(s), anti-caking agent(s), adjuvant(s), filler(s)Zsuspension aid(s), colorant(s)Zcolouring agent(s)Zdye(s), carrier(s), buffering agent(s), polymer(s), safener(s), rheology modifier(s), solvent(s), co-solvent(s) or mixtures thereof.

9. . The stable synergistic insecticidal composition as claimed in claim 8, wherein the surfactant(s) andZor dispersing agent andZor co-dispersant isZare selected from the group comprising polymeric anionic dispersant, polyarylphenyl ether phosphate, tristyryl phenol ethoxylate, Polymethyl methacrylatepolyethylene glycol graft copolymer, acrylate copolymer, acrylic copolymer, polymeric dispersant, Calcium salt of alkyl benzene sulphonate, Non-ionic surfactant, polyalkoxylated butyl ether, acrylic graft copolymer, Sodium methyl oleoyl taurate , non-ionic proprietary surfactant, Methyl naphthalene sulfonic acid, polymer with formaldehyde, sodium salt, ethoxylated tristryl phenol Sulphate, alkyl naphthalene formaldehyde condensate , naphthalene sulfonic acid, phenol sulfonic acid-formaldehyde polycondensation as sodium salt, sodium salt condensate with formaldehyde, ethoxylated oleyl cetyl alcohol, Sodium Alkyl Naphthalene Sulfonate Blend, polyalkelene glycol ether, Sodium Isopropyl Naphthalene Sulfonate, Dialkyl naphthalene sulphonate sodium salt, Naphthalene Sulphonic Acid, Formaldehyde, Acrylate graft Copolymer, Ethoxylated fatty glyceride , Ethoxylated Polyarylphenol Phosphate Ester, Lignosulfonic Acid, Sodium Salt, Sulfomethylated, ethoxylated fatty alcohol, methyl naphthalene sulfonic acid, polymer with formaldehyde sodium salt, Sodium Alkylnaphthalene Sulfonate Formaldehyde Condensate, Sodium polymethyl methacrylate, sodium polyacrylate, alkyl naphthalene sulfonate formaldehyde condensate or its sodium salt , Sodium Naphthalene Sulfonate formaldehyde condensate, sodium lignosulphonate, calciumlignosulphonate, Sodium Alkyl Naphthalene Sulfonate, Naphthalene Sulphonic Acid, Formaldehyde , alkylphenol polyoxyethylene ether, sodium salt of naphthalene sulfonate condensate, alkyl naphthalene sulfonate condensate blend, polymeric surfactant, sodium salt of alkyl naphthalene sulfonate, sodium salt of methyl naphthalene sulfonate, polycarboxylate, naphthalene sulfonic acid-branched and linear derivative sodium salts, fatty alcohol polyoxyethylene ether, alcohol polyglycol ether, non-aqueous dispersant - nonionic polymeric surfactant, aqueous dispersant - polymeric amphoteric aqueous dispersant or mixtures thereof and present in the range of 0.1-20% by weight of the composition.

10. . The stable synergistic insecticidal composition as claimed in claim 8, wherein the wetting agent is / are selected form the group comprising tristyrylphenol ethoxylate non-ionic emulsifier, mixture of non-ionic surfactants, Blend of Anionic and Non-ionic, alkoxylated alcohol, block copolymer, alcohol polyglycol ether, alkyl olefin sulphates, dioctyl sulpho succinate, alkyl naphthalene sulphate , Di-isopropyl Napthalene sulphonate, Benzenesulfonic acid, Hydroxy polymer with formaldehyde, Phenol and Urea sodium salt, Polyalkoxy ethers, alkyl phenol ethoxylates, tri-styrenated phenol ethoxylate, EO / PO block co-polymers, butyl polyalkylene oxide block copolymer, sodium lauryl sulphate, sodium sulphates or mixtures thereof and present in the range of 0.1-20% by weight of the total composition.

11. . The stable synergistic insecticidal composition as claimed in claim 8, wherein the defoamer or antifoaming agent is / are selected from the group comprising silicon emulsion based anti-foam agents, Siloxane polyalkyleneoxide, Polydimethylsiloxane, trisiloxane ethoxylates, silicone oil, silicone compound, C10~C20 saturated fat acid compounds or C8~C10 aliphatic alcohols compound, vegetable oil based antifoam, tallow based fatty acids, polyalkyleneoxide polydimethylsiloxane emulsion and mixtures thereof and present in the range of 0.01-5.0 % by weight of the composition.

12. . The stable synergistic insecticidal composition as claimed in claim 8, wherein the antifreezing agent is / are selected from the group comprising glycol, propylene glycol, mono ethylene glycol, glycerine, diethylene glycol, sorbitol, urea, mannitol, polyethylene glycol or mixtures thereof and present in the range of 1.0-20% by weight of the composition.

13. The stable synergistic insecticidal composition as claimed in claim 8, wherein the filler is / are selected from the group comprising silicon dioxide, china-clay, kaolin, starch, bentonite, precipitated silica, fumed silica, lactose monohydrate, talcum powder, lactose, ammonium sulphate, water, sodium Sulphate, magnesium sulphate, sodium citrate, sodium chloride, potassium chloride and mixtures thereof and present in the range of 0.1-60 % by weight of the composition.

14. The stable synergistic insecticidal composition as claimed in claim 8, wherein the anti-caking agent is / are selected from the group comprising of group of talc, hydrous magnesium silicate, magnesium carbonate, calcium carbonate, precipitate silica, silica powder, hydrophobic fumed silica and mixtures thereof and present in the range of 0.1-10% by weight of the composition.

15. The stable synergistic insecticidal composition as claimed in claim 8, wherein the carrier is / are selected from the group consisting of silicon dioxide, china clay, kaolin, starch, bentonite, precipitated silica, silica powder, fumed silica, lactose monohydrate, talcum powder, lactose, ammonium sulpha or mixture thereof and present in the range of 0.1-45 % by weight of the composition.

16. . The stable synergistic insecticidal composition as claimed in claim 8, wherein the biocide or anti-microbial agent(s) is / are selected from 1, 2,- Benzisothiazolin -3-one, blends of 1,2,- benzisothiazolin- 3-one and 2-methyl-4-isothiazolin-3-one, 5-chloro-2-methyl-4-isothiazolin-3-one, blends of 5-chloro-2- methyl-4-isothiazolin-3-one and 2-methyl-4-isothiazolin-3-one, zinc 1 -hydroxy -2(1 H)-pyridinethione, blends of zinc l-hydroxy-2(lH)-pyridinethione and zinc oxide, and 2-n-octyl-4- isothiazolin-3-one or mixture thereof and present in the range of 0.01 to 10 % by weight of the composition.

17. . The stable synergistic insecticidal composition as claimed in claim 8, wherein the rheology modifier or thickeners or thickening agents is / are selected from polysaccharides, carboxymethyl cellulose, bentonite clay, aluminium magnesium silicate, hydroxy propyl cellulose, xanthan gum, gum arabic, Silica powder, gaur gum, carbomer, chitosan, precipitated silica or mixtures thereof and present in the range of 0.01-5.0 % by weight of the composition.

18. . The stable synergistic insecticidal composition as claimed in claim 8, wherein the emulsifier(s) is / are selected from group consisting of araliphatic or aliphatic non-ionic oil emulsifier- ethoxylated sorbitol hexaester derived from oleic acid, emulsifier such as ethoxylated mono-, di- and trialkylphenols, ethoxylates of long-chain alcohols and polyethylene oxide / polypropylene oxide homo- and copolymers, EO / PO block copolymers, Polymeric emulsifier (Nonionic polyalkylene oxide block copolymer), Ethoxylates of long-chain alkanols, Castor oil ethoxylate , ethoxylated monoalkylphenol, ethoxilates of cetyl alcohol and / or stearyl alcohol ; Tristyrylphenol ethoxylate-20 mole, Ethoxylated Tristyrylphenol ,and Anionic emulsifier such as alkali metal and ammonium salts of alkyl sulfates, of hemisulfates of ethoxylated alkanols and ethoxylated alkylphenols, alkylsulfonic acids, bis(phenylsulfonic acid) ethers and their alkali metal or ammonium salts, sodiumlaurylsulfate, sodium (cetyl / stearyl) sulfate or mixture thereof and present in the range of 0.01 -20 % by weight of the composition.

19. . The stable synergistic insecticidal composition as claimed in claim 8, wherein the solvent(s) and co-solvent are selected from polar and non-polar solvent from the group comprising heavy aromatic hydrocarbon, N methyl pyrollidone (NMP) , Solvent Naphtha (Solvent C-9), Di methyl sulfoxide (DMSO), Dimethylformamide (DMF), N- alcohol, 2-ethyl hexanol , alkyl amide, vegetable oil, mineral oil, distilled water, aromatic solvents, water or mixtures thereof and present in the range of 1.0 to 20% by weight of the composition.

20. . The stable synergistic insecticidal composition as claimed in Claim 8, wherein the colouring pigment(s) / dye(s) are selected from red dye FGR03, Permanent Rubin L5-B-01, pigment blue 15:4, pigment blue 15:3, pigment blue 15:2, pigment blue 15:1 , pigment blue 80, pigment yellow 1 , pigment yellow 13, pigment red 112, pigment red 48:2, pigment red 48:1 , pigment red 57: 1 , pigment red 53:1 , pigment orange 43, pigment orange 34, pigment orange 5, pigment green 36, pigment green 7, pigment white 6, pigment brown 25, basic violet 10, basic violet 49, violet 23, acid red 51 , acid red 52, acid red 14, acid blue 9, acid yellow 23, basic red 10, basic red 108 or mixtures thereof and present in the range of 0.01- 10.0 % by weight of the composition.

21. . The stable synergistic insecticidal composition as claimed in claim 8, wherein the polymer(s) is / are selected from isocyanate, polyisocyanate used is toluene-2, 4-diisocyanate (TDI), diethylenetriamine (DET A), ethylene diamine (EDA), triethylenetetramine (TETA), and / or hexamethylene diamine (HMDA), diethanolglycine sodium salt, ethanoldiglycine disodium salt, hydroxymonocarboxylic acid compounds, hydroxy dicarboxylic acid compounds, tetrasodium N,N-bis(carboxylatomethyl)-L-glutamate (GLDA), methylene diisocyanate (MDI), and / or low molecular weight polydiisocynates or mixtures thereof and present in the range of 0.01- 5.0 % by weight of the composition.

22. . The stable synergistic insecticidal composition as claimed in claim 8, wherein the bidner(s) is / are selected from polyvinylpyrrolidone, polyvinyl alcohol, methyl cellulose, and carboxymethyl cellulose, polyisocyanate, polyterpene resin or mixtures thereof and present in the range of 0.01- 40 % by weight of the composition.

23. . The stable synergistic insecticidal composition as claimed in any one of the claims 1 to 22, wherein the composition is in form of Emulsifiable concentrate (EC), Capsule suspension (CS), Dispersible concentrate (DC), Dustable powder (DP), Powder for dry seed treatment (DS), Emulsifiable granule (EG), Emulsion water-in-oil (EO), Emulsifiable powder (EP), Emulsion for seed treatment (ES), Emulsion oil- in-water (EW), Flowable concentrate for seed treatment (FS), Granules (GR Micro -emulsion concentrate(MEC), Oil-dispersion (OD), Oil miscible flowable concentrate (OF), Oil miscible liquid (OL), Oil dispersible powder (OP), Suspension concentrate (SC), Suspension concentrate for direct application (SD), Suspo-emulsion (SE), Water soluble granule (SG), Soluble concentrate (SL), Spreading oil (SO), Water soluble powder (SP), Water soluble tablet (ST), Ultra-low volume (ULV) suspension, Tablet (TB), Ultralow volume (ULV) liquid, Water dispersible granules (WG), Wettable powder (WP), Water dispersible powder for slurry seed treatment (WS), Water dispersible tablet (WT), a mixed composition of CS and SC (ZC) or a mixed composition of CS and SE (ZE) and a mixed composition of CS and EW (ZW).

24. . The stable synergistic insecticidal composition as claimed in claims 1 to 23, wherein the use of said composition promotes plant health, growth and increases plant yield in the field.

25. A kit-of-parts comprising a plurality of components, wherein said plurality of components comprises:A) compound of Formula I, chemically known as 7V-[methyloxido[l-[6-(trifluoromethyl)-3- pyridinyl]ethyl]-X4-sulfanylidene]cyanamide or its agrochemically acceptable salts, esters and derivatives;B) Compound of Formula II, chemically known as 4-bromo-2-(4-chlorophenyl)-l-(ethoxymethyl)-5-(trifluoromethyl)-lH-pyrrole-3-carbonitrile or its agrochemically acceptable salts, esters and derivatives; andC) at least one pyridine azomethine insecticide selected from pymetrozine and pyrifluquinazon or its agrochemically acceptable salts, esters and derivatives

26. . A process for preparing a stable synergistic insecticidal composition as claimed in claims 1- 23.

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