Control technology of crack arrest effect based on heterogeneous stiffness structure and stiffness-variable materials

Abstract

The present invention relates to an adhesive patch comprising: a stiffness-variable material layer including a plurality of segments; and a flexible material layer filled in the spaces between patterns.

Description

Control technology for peel resistance effect based on heterogeneous stiffness structures and variable stiffness materials

[0001] The present invention relates to a technology for controlling peeling resistance effect based on a heterogeneous rigid structure and variable rigidity material.

[0002] Recently, interest in skin patch products, such as skin condition monitoring sensor patches, has been increasing. Consequently, research into the development and improvement of skin patches has steadily increased. Key issues include persistent issues such as poor adhesion due to oil and other factors, and poor adherence to facial contours, leading to a high demand for improvements. Furthermore, demand is growing for adhesive patches that do not require chemical adhesives. Furthermore, there is a growing need for improved adhesiveness in skin patches.

[0003] Conventional medical tapes use chemical adhesives to create adhesive strength. However, these chemical adhesives can severely damage the delicate epidermis of babies and the elderly, and once the bandage is removed, the adhesive strength becomes very weak.

[0004] In addition, since existing shape memory polymer adhesives have only a homogeneous structure, they tend to have low peel strength, low vertical adhesion strength, and gradually deteriorate switching characteristics such as shape adaptation and shape recovery.

[0005] Therefore, there is a need to develop a method and a shape memory polymer adhesive that can lower the peel resistance of the shape memory polymer adhesive and significantly increase the peel strength and adhesive strength.

[0006] The background technology described above is something that the inventor possessed or acquired in the process of deriving the disclosure of the present application, and cannot necessarily be said to be a publicly known technology disclosed to the general public prior to the present application.

[0007] The present invention aims to solve the above-described problem by providing an adhesive patch and a medical device attachable to the skin including the same.

[0008] The adhesive patch according to the present invention comprises a repeating structure of a rigid-variable material layer and a flexible material layer including a plurality of shape memory polymer segments having a glass transition temperature higher than room temperature, such that when a peel line passes from a flexible region to a rigid region (segment), the segments with high rigidity can resist deformation, thereby significantly increasing the peel strength. In addition, the peel resistance effect can be eliminated by temporarily converting a heterogeneous structure into a homogeneous structure by lowering the rigidity of the shape memory polymer through heating. The switching characteristics can be further maximized through shape adaptation and shape recovery, which are characteristics of existing shape memory polymer adhesives.

[0009] However, the problems to be solved by the present invention are not limited to the problems mentioned above, and other problems not mentioned can be clearly understood by a person having ordinary skill in the relevant technical field from the description below.

[0010] An adhesive patch according to the present invention comprises a rigid-deformable material layer including a plurality of segments; and a flexible material layer filled in a space between the rigid-deformable material layers.

[0011] In one embodiment, the rigid-variable material layer may form a pattern.

[0012] According to one embodiment, the pattern may be at least one pattern selected from the group consisting of a square array pattern, a linear array pattern, a kirigami array pattern, a serpentine array pattern, a honeycomb array pattern, and a circular array pattern.

[0013] In one embodiment, the segment may comprise a shape memory polymer.

[0014] According to one embodiment, the shape memory polymer may have a glass transition temperature of 45°C or higher.

[0015] According to one embodiment, the rigid-variable material layer may have the same adhesive strength as the flexible material layer when the temperature is higher than the glass transition temperature, and the adhesive strength may be less than 4.5 kPa.

[0016] According to one embodiment, the rigid-variable material layer may have a peel strength of 150 N / m or more and an adhesive strength of 215 kPa or more when the rigid-variable material layer is lower than the glass transition temperature.

[0017] According to one embodiment, the rigid-variable material layer and the flexible material layer may each include at least one polymer selected from the group consisting of polyurethane, polyamide, epoxy, olefin, polysiloxane, polycarbonate or a block copolymer thereof, polydimethylsiloxane, lauryl methacrylate, stearyl acrylate, polycaprolactone, polyurethane acrylate, polyvinyl chloride, polyethylene glycol dimethacrylate, tertbutyl acrylate, stearyl methacrylate, polyimide, polyethylene glycol diacrylate, acrylic acid, and chitosan.

[0018] In one embodiment, the spacing of the segments may be from 0.2 mm to 1 mm, and the aspect ratio of the segments may be from 1:1 to 1:4.

[0019] According to one embodiment, based on 100 parts by weight of the adhesive patch, the rigid-variable material layer may be 60 parts by weight to 70 parts by weight, and the flexible material layer may be 30 parts by weight to 40 parts by weight.

[0020] According to one embodiment, when the glass transition temperature of the rigid-variable material layer is lower than the glass transition temperature of the rigid-variable material layer, the peel strength ratio of the rigid-variable material layer and the flexible material layer may be 1:1 to 30:1.

[0021] According to one embodiment, in the cross-section of the adhesive patch, the total area ratio of the rigid-variable material layer and the flexible material layer may be 1:0.5 to 1:8.

[0022] A medical device attachable to the skin according to the present invention includes an adhesive patch of the present invention.

[0023] The present invention can provide an adhesive patch and a medical device attachable to the skin including the same by using a peeling resistance effect control technology based on a heterogeneous rigidity structure and a variable rigidity material.

[0024] Specifically, the adhesive patch according to the present invention and the medical device attachable to the skin including the same include a rigid-deformable material layer including a shape memory polymer and a flexible material layer filled in the space between the rigid-deformable material layers, thereby increasing the peel strength and bonding strength of the adhesive patch, and further maximizing the switching characteristics through shape adaptation and shape recovery, which are characteristics of the shape memory polymer adhesive, depending on the heating temperature. In addition, by lowering the rigidity of the shape memory polymer through heating, it is possible to temporarily transform from a heterogeneous structure to a homogeneous structure, thereby reducing the peel resistance, thereby providing an adhesive patch with excellent physical properties and a medical device attachable to the skin including the same.

[0025] Figure 1 illustrates an example of a modification of an adhesive patch according to one embodiment of the present invention.

[0026] FIG. 2 is a diagram showing the repeating structure of a rigid-variable material layer and a flexible material layer of a portion of an adhesive patch according to one embodiment of the present invention.

[0027] Hereinafter, embodiments are described in detail with reference to the attached drawings. However, the embodiments may be modified in various ways, and the scope of the patent application is not limited or restricted by these embodiments. It should be understood that all modifications, equivalents, or alternatives to the embodiments are included within the scope of the patent application.

[0028] The terms used in the examples are for illustrative purposes only and should not be construed as limiting. Singular expressions include plural expressions unless the context clearly dictates otherwise. In this specification, terms such as "comprise" or "have" are intended to specify the presence of a feature, number, step, operation, component, part, or combination thereof described in the specification, but should be understood to not preclude the presence or addition of one or more other features, numbers, steps, operations, components, parts, or combinations thereof.

[0029] Unless otherwise defined, all terms used herein, including technical or scientific terms, have the same meaning as commonly understood by a person of ordinary skill in the art to which the embodiments pertain. Terms defined in commonly used dictionaries should be interpreted as having a meaning consistent with their meaning in the context of the relevant technology, and shall not be interpreted in an idealized or overly formal sense unless explicitly defined herein.

[0030] In addition, when describing with reference to the attached drawings, the same components will be given the same reference numerals regardless of the drawing numbers, and redundant descriptions thereof will be omitted. When describing an embodiment, if it is determined that a detailed description of a related known technology may unnecessarily obscure the gist of the embodiment, the detailed description thereof will be omitted. In addition, when describing a component of an embodiment, terms such as first, second, A, B, (a), (b), etc. may be used. These terms are only to distinguish the component from other components, and the nature, order, or sequence of the component is not limited by the terms. When a component is described as being "connected," "coupled," or "connected" to another component, it should be understood that the component may be directly connected or connected to the other component, but another component may also be "connected," "coupled," or "connected" between each component.

[0031] Components included in one embodiment and components with common functions will be described using the same names in other embodiments. Unless otherwise stated, the descriptions given in one embodiment can be applied to other embodiments, and detailed descriptions will be omitted to the extent of overlap.

[0032] An adhesive patch according to the present invention comprises a rigid-deformable material layer including a plurality of segments; and a flexible material layer filled in a space between the rigid-deformable material layers.

[0033] According to the present invention, the adhesive patch can lower the stiffness of the shape memory polymer contained in the rigid-variable material layer through heating, thereby improving surface adaptability, thereby increasing the adhesion of the patch (shape adaptation). Thereafter, the patch is cooled by temperature change in the bonded shape, thereby solidifying its shape (variable stiffness), and can be strongly fixed to the skin (strong adhesion). When the fixed patch is to be removed, the patch can be heated again to lower the stiffness and restore its shape, thereby allowing it to be easily removed.

[0034] An adhesive patch according to the present invention comprises a repeating structure of a rigid-variable material layer and a flexible material layer including a plurality of shape memory polymer segments having a glass transition temperature higher than room temperature, such that when a peel line passes from a flexible region to a rigid region (segment), the segments with high rigidity can resist deformation, thereby significantly increasing the peel strength. In addition, the peel resistance effect can be eliminated by temporarily converting a heterogeneous structure into a homogeneous structure by lowering the rigidity of the shape memory polymer through heating. The switching characteristics can be further maximized through shape adaptation and shape recovery, which are characteristics of existing shape memory polymer adhesives.

[0035] According to one embodiment, the flexible material layer is flexible and has good elasticity so as to prevent detachment when bending a part such as a joint, and the rigid-deformable material layer is easily deformed into a flexible state at high temperatures and can provide a fixing force with high rigidity at room temperature. Unlike conventional adhesive patches that only include shape memory polymers that crack when the skin is deformed, the adhesive patch of the present invention can stably maintain the shape of the patch and improve adhesive force even when skin bending occurs at a joint area due to the elasticity of the flexible material layer and the rigid-deformable material layer and the repeating structure of the flexible material layer.

[0036] In one embodiment, the rigid-variable material layer may form a pattern.

[0037] FIG. 2 is a diagram showing the repeating structure of a rigid-variable material layer and a flexible material layer of a portion of an adhesive patch according to one embodiment of the present invention.

[0038] Referring to FIG. 2, the repeating structure of the rigid-variable material layer and the flexible material layer of a portion of an adhesive patch according to one embodiment of the present invention can be simply confirmed, and unlike an adhesive patch including only a conventional shape memory polymer, when a peeling line passes through a rigid-variable material layer including a plurality of segments in a flexible material layer, the segments having high rigidity can resist deformation, so that the peeling strength can be greatly increased, and the adhesive strength can also be improved.

[0039] According to one embodiment, the pattern may be at least one pattern selected from the group consisting of a square array pattern, a linear array pattern, a kirigami array pattern, a serpentine array pattern, a honeycomb array pattern, and a circular array pattern.

[0040] According to one embodiment, the types of the above patterns are merely examples, and other patterns other than the above patterns may be freely adopted and used in consideration of adhesion to the skin or mechanical properties.

[0041] According to one embodiment, an example of a patch of the square array pattern is shown in Fig. 1. Fig. 1 shows the overall structure of the patch, and a flexible material layer may be formed in a space between the rigid-deformable material layer formed in a square array pattern and the pattern. In addition, the thickness of the adhesive patch including the rigid-deformable material layer including a plurality of segments; and the flexible material layer filled in the space between the pattern; is 10 100 inland The above square array pattern has the characteristic of securing isotropic mechanical properties in the horizontal direction of the pattern. Since it can deform horizontally in accordance with body movement along with high adhesive strength, it can have high resistance to peeling.

[0042] In one embodiment, the segment may comprise a shape memory polymer.

[0043] According to one embodiment, the shape memory polymer is a material whose rigidity can be changed by heat and then restored. For example, the shape memory polymer may include at least one of PCL (Polycaprolactone), PUA (Polyurethane acrylate), and PVC (Polyvinyl chloride). An example will be described using a polymer that combines PCL (Polycaprolactone) and PUA (Polyurethane acrylate). PCL (Polycaprolactone) is a polymer that has a melting point of 60°C depending on its molecular weight. PUA (Polyurethane acrylate) is a polymer whose physical properties do not change even when subjected to heat of 100°C or higher. A polymer that combines PCL (Polycaprolactone) and PUA (Polyurethane acrylate) can undergo fluidization and solidification starting from 60°C. Therefore, shape memory and shape restoration can be achieved at 60°C. However, it is not limited to this, and various polymers whose rigidity changes with heat can be applied.

[0044] According to one embodiment, the shape memory polymer may have a glass transition temperature of 45°C or higher.

[0045] Figure 1 illustrates an example of a modification of an adhesive patch according to one embodiment of the present invention.

[0046] Referring to Fig. 1, a flexible material layer is filled in the interspace between a rigid-deformable material layer including a plurality of segments having a square array pattern. The shape memory polymer has a glass transition temperature and a melting point of 45°C or higher, and exists in an opaque and rigid form at room temperature (25°C), so that the adhesive patch can have strong adhesive strength without cracks. However, when the temperature rises due to heating, the rigidity may decrease at 45°C and change to a flexible state. By heating, the rigidity of the rigid-deformable material layer may be lowered, temporarily changing from a heterogeneous structure to a homogeneous structure, thereby eliminating the peeling resistance effect. The rigid-deformable material layer including the shape memory polymer can recover its rigidity again at room temperature. When the temperature is 45°C or higher, the adhesive patch may be easily detached due to crack propagation.

[0047] According to one embodiment, the rigid-variable material layer may have the same adhesive strength as the flexible material layer when the temperature is higher than the glass transition temperature, and the adhesive strength may be less than 4.5 kPa.

[0048] According to one embodiment, the rigid-variable material layer can have the same adhesive strength as the flexible material layer when the rigid-variable material layer is higher than the glass transition temperature, and the adhesive patch can have a homogeneous structure by temporarily transforming from a heterogeneous structure to a homogeneous structure.

[0049] According to one embodiment, when the rigid-deformable material layer is maintained at a temperature higher than the glass transition temperature, the bending stiffness of the rigid-deformable material layer may change equally regardless of the pattern. Since the bending stiffness is the same regardless of the patch position, the peeling propagation may occur in a manner similar to the peeling propagation of a general adhesive tape. In addition, when the temperature higher than the glass transition temperature is maintained, the peeling adhesive strength may be the same as the adhesive strength of the adhesive layer material itself. Since the adhesive layer material is composed of a shape memory polymer, it can spontaneously repel an adhesive target with a rough surface through shape recovery after heating, thereby minimizing the contact area and having a lower adhesive strength, thereby enabling easy detachment.

[0050] According to one embodiment, when the rigid-variable material layer has a glass transition temperature or higher and an adhesive strength of 4.5 kPa or higher, there may be a problem in that the patch cannot be smoothly removed without any catch when removed.

[0051] According to one embodiment, the rigid-variable material layer may have a peel strength of less than 2.5 N / m when the temperature is higher than the glass transition temperature, and when the peel strength is 2.5 N / m or higher, there may be a problem in that the patch cannot be peeled off smoothly without any catch when being peeled off.

[0052] According to one embodiment, the rigid-variable material layer may have a peel strength of 150 N / m or more and an adhesive strength of 215 kPa or more when the rigid-variable material layer is lower than the glass transition temperature.

[0053] In one embodiment, when a temperature below the glass transition temperature is maintained, the bending stiffness of the rigid-deformable material layer may vary depending on the regions of the rigid-deformable material layer and the flexible material layer. Since the bending stiffness varies depending on the patch position, the peel propagation may be suppressed at the moment when the peel front crosses the interface from the rigid-deformable material layer to the flexible material layer. This crack arrest phenomenon may be a phenomenon that occurs due to a momentary change in the strain energy of the adhesive patch. While the deformation is maintained in accordance with the bending shape of the adhesive patch for peeling within the region of the flexible material layer, the rigid-deformable material layer has high rigidity and thus does not easily undergo deformation, resulting in a momentary change in the bending shape of the patch. This change in strain energy creates a momentary strong peel strength. In addition, since the adhesive layer material is composed of a shape memory polymer, it is possible to ensure close contact regardless of the roughness of the target surface through heating, pressing, and cooling, thereby securing a higher bonding strength.

[0054] According to one embodiment, when the rigid-variable material layer has a temperature lower than the glass transition temperature and a peel strength of the rigid-variable material layer of less than 150 N / m, the peel resistance effect may be reduced, resulting in a problem in that the patch is easily peeled off.

[0055] In one embodiment, in one embodiment, when the rigid-variable material layer has a temperature lower than the glass transition temperature and an adhesive strength of the rigid-variable material layer is lower than 215 kPa, there may be a problem in that the patch is easily detached due to reduced adhesive strength.

[0056] According to one embodiment, the rigid-variable material layer and the flexible material layer may each include at least one polymer selected from the group consisting of polyurethane, polyamide, epoxy, olefin, polysiloxane, polycarbonate or a block copolymer thereof, polydimethylsiloxane, lauryl methacrylate, stearyl acrylate, polycaprolactone, polyurethane acrylate, polyvinyl chloride, polyethylene glycol dimethacrylate, tertbutyl acrylate, stearyl methacrylate, polyimide, polyethylene glycol diacrylate, acrylic acid, and chitosan.

[0057] In one embodiment, the polymer types of the rigid-variable material layer and the flexible material layer may be the same, partially the same, or completely different.

[0058] In one embodiment, the spacing of the segments may be from 0.2 mm to 1 mm, and the aspect ratio of the segments may be from 1:1 to 1:4.

[0059] In one embodiment, the spacing of the segments may be 0.2 mm to 1 mm; 0.3 mm to 1 mm; 0.4 mm to 1 mm; 0.5 mm to 1 mm; 0.6 mm to 1 mm; 0.7 mm to 1 mm; 0.8 mm to 1 mm; 0.2 mm to 0.9 mm; 0.2 mm to 0.8 mm; 0.2 mm to 0.7 mm; 0.2 mm to 0.6 mm; 0.2 mm to 0.5 mm; 0.2 mm to 0.4 mm; 0.3 mm to 0.5 mm; 0.4 mm to 0.6 mm; 0.5 mm to 0.7 mm; 0.6 mm to 0.8 mm.

[0060] In one embodiment, the spacing of the segments, if outside the above range, may result in a problem of reduced crack arrest.

[0061] In one embodiment, the aspect ratio of the segment may be 1:1 to 1:4; 1:1 to 1:3.5; 1:1 to 1:3; 1:1 to 1:2.5; 1:1 to 1:2; 1:1 to 1:1.5; 1:1 to 1:1.2; 1:1.2 to 1:4; 1:1.5 to 1:4; 1:2 to 1:4; 1:2.5 to 1:4; 1:3 to 1:4; 1:3.5 to 1:4;

[0062] In one embodiment, if the aspect ratio of the segment is outside the above range, there may be a problem of reduced crack arrest.

[0063] In one embodiment, for optimal crack arrest, the maximum length or width of the segment should be greater than the stress field.

[0064] That is, the maximum length of the above segment is

[0065] It should be bigger than that.

[0066] F is the adhesive strength of the unpatterned patch

[0067] is the bending stiffness of the flexible region

[0068] In one embodiment, the minimum length of the segment may be at least 0.7 mm.

[0069] According to one embodiment, the spacing of the segments is

[0070] It should be bigger than that.

[0071] L rigid : Maximum length of the stiffness-variable material layer segment

[0072] EI_1: Bending stiffness of the flexible material layer

[0073] EI_2: Bending stiffness of the stiffness-variable material layer

[0074] According to one embodiment, based on 100 parts by weight of the adhesive patch, the rigid-variable material layer may be 60 parts by weight to 70 parts by weight, and the flexible material layer may be 30 parts by weight to 40 parts by weight.

[0075] According to one embodiment, based on 100 parts by weight of the adhesive patch, the amount of the rigid-variable material layer may be 60 parts by weight to 70 parts by weight; 62 parts by weight to 70 parts by weight; 64 parts by weight to 70 parts by weight; 66 parts by weight to 70 parts by weight; 68 parts by weight to 70 parts by weight; 60 parts by weight to 68 parts by weight; 60 parts by weight to 66 parts by weight; 60 parts by weight to 64 parts by weight; 60 parts by weight to 62 parts by weight; 62 parts by weight to 65 parts by weight; 63 parts by weight to 67 parts by weight; 65 parts by weight to 69 parts by weight.

[0076] According to one embodiment, based on 100 parts by weight of the adhesive patch, the flexible material layer may be 30 parts by weight to 40 parts by weight; 32 parts by weight to 40 parts by weight; 34 parts by weight to 40 parts by weight; 36 parts by weight to 40 parts by weight; 38 parts by weight to 40 parts by weight; 30 parts by weight to 38 parts by weight; 30 parts by weight to 35 parts by weight; 30 parts by weight to 33 parts by weight; 32 parts by weight to 35 parts by weight; 33 parts by weight to 37 parts by weight; 35 parts by weight to 38 parts by weight.

[0077] According to one embodiment, based on 100 parts by weight of the adhesive patch, if the amount of the rigid-deformable material layer is less than 60 parts by weight, the spacing between patterns becomes wider and the bending rigidity of the rigid-deformable material layer decreases, making it difficult to obtain a large peeling resistance effect, which may cause a problem of lowering the peel strength, and if it exceeds 70 parts by weight, the spacing between patterns becomes narrower and the bending rigidity of the rigid-deformable material layer increases, but the size of the flexible material layer becomes smaller than the characteristic length, making it difficult to obtain an optimal peeling resistance effect (crack arrest), which may cause problems of easy detachment and insufficient adhesive strength below the glass transition temperature.

[0078] According to one embodiment, based on 100 parts by weight of the adhesive patch, when the flexible material layer is less than 30 parts by weight, the gap between patterns becomes narrower, so that the bending rigidity of the rigid-deformable material layer increases, but the size of the flexible material layer becomes smaller than the characteristic length, so that the optimal peeling resistance effect (crack arrest) cannot be obtained, which may cause problems of easy detachment and insufficient adhesive strength below the glass transition temperature, and when it exceeds 40 parts by weight, the gap between patterns becomes wide, so that the bending rigidity of the rigid-deformable material layer decreases, making it difficult to obtain a large peeling resistance effect, so that the peeling strength may be lowered.

[0079] According to one embodiment, when the glass transition temperature of the rigid-variable material layer is lower than the glass transition temperature of the rigid-variable material layer, the peel strength ratio of the rigid-variable material layer and the flexible material layer may be 1:1 to 30:1.

[0080] According to one embodiment, when the glass transition temperature of the rigid-deformable material layer is lower than the glass transition temperature, the peel strength ratio of the rigid-deformable material layer and the flexible material layer is 1:1 to 30:1; 1:1 to 25:1; 1:1 to 20:1; 1:1 to 15:1; 1:1 to 10:1; 1:1 to 5:1; 1:1 to 3:1; 1:1 to 2:1; 2:1 to 30:1; 3:1 to 30:1; 5:1 to 30:1; 10:1 to 30:1; 15:1 to 30:1; 20:1 to 30:1; 25:1 to 30:1; It may be 5:1 to 10:1; 10:1 to 15:1; 15:1 to 20:1; 20:1 to 25:1; 25:1 to 28:1;

[0081] According to one embodiment, when the glass transition temperature of the rigid-deformable material layer is lower than that of the flexible material layer, the peel strength of the rigid-deformable material layer and the flexible material layer are similar, but the reason why they are not easily separated may be due to the peel resistance effect of the rigid-deformable material layer in a hard state.

[0082] According to one embodiment, when the glass transition temperature of the rigid-variable material layer is lower than the glass transition temperature of the rigid-variable material layer, the peel strength ratio of the rigid-variable material layer and the flexible material layer may be such that the patch may be easily separated if it is outside the above range.

[0083] According to one embodiment, in the cross-section of the adhesive patch, the total area ratio of the rigid-variable material layer and the flexible material layer may be 1:0.5 to 1:8.

[0084] According to one embodiment, in the cross-section of the adhesive patch, the total area ratio of the rigid-variable material layer and the flexible material layer may be 1:0.5 to 1:8; 1:1 to 1:8; 1:2 to 1:8; 1:4 to 1:8; 1:5 to 1:8; 1:6 to 1:8; 1:7 to 1:8; 1:0.5 to 1:7; 1:0.5 to 1:6; 1:0.5 to 1:5; 1:0.5 to 1:4; 1:0.5 to 1:3; 1:0.5 to 1:2; 1:0.5 to 1:1; 1:1 to 1:3; 1:2 to 1:5; 1:4 to 1:7;

[0085] According to one embodiment, in the cross-section of the adhesive patch, when the total area ratio of the rigid-deformable material layer and the flexible material layer is less than 1:0.5, the gap between the patterns becomes narrow, so that the bending rigidity of the rigid-deformable material layer increases, but the size of the flexible material layer becomes smaller than the characteristic length, so that the optimal peeling resistance effect (crack arrest) cannot be obtained, which may cause problems of easy detachment and insufficient adhesive strength below the glass transition temperature, and when it exceeds 1:8, the gap between the patterns becomes wide, so that the bending rigidity of the rigid-deformable material layer decreases, making it difficult to obtain a large peeling resistance effect, so that the peeling strength may be lowered.

[0086] A medical device attachable to the skin according to the present invention comprises an adhesive patch of the present invention.

[0087] In one embodiment, the adhesive patch according to the present invention can be used in a medical device attachable to the skin. The adhesive patch according to the present invention provides sufficient adhesive strength to the skin, so that it can be attached to the skin of the body. The skin can be freely attached to the skin of areas where bio-signals can be collected, such as the wrist, chest (heart), scalp, neck, ankle, and arm. In addition, the adhesive patch according to the present invention can be used in industrial adhesive patches, and any field in which the adhesive patch can be utilized is not limited thereto.

[0088] Although the embodiments have been described above, those skilled in the art will appreciate that various technical modifications and variations can be applied based on the above. For example, appropriate results can still be achieved even if the described techniques are performed in a different order than described, and / or components of the described systems, structures, devices, circuits, etc. are combined or combined in a different manner than described, or are replaced or substituted with other components or equivalents.

[0089] Therefore, other implementations, other embodiments, and equivalents to the claims also fall within the scope of the claims described below.

Claims

1. A rigid-variable material layer comprising a plurality of segments; and A flexible material layer filled in the space between the rigid-variable material layers; Adhesive patch.

2. In paragraph 1, The above rigid-variable material layer forms a pattern, Adhesive patch.

3. In paragraph 2, The above pattern is at least one pattern selected from the group consisting of a square array pattern, a linear array pattern, a kirigami array pattern, a serpentine array pattern, a honeycomb array pattern, and a circular array pattern. Adhesive patch.

4. In paragraph 1, The above segment is, Containing a shape memory polymer, Adhesive patch.

5. In paragraph 4, The above shape memory polymer is, Having a glass transition temperature of 45 ℃ or higher, Adhesive patch.

6. In paragraph 1, The above rigid-variable material layer is, If the glass transition temperature is higher than the above, it has the same adhesive strength as the flexible material layer, and the adhesive strength is less than 4.5 kPa. Adhesive patch.

7. In paragraph 1, The above rigid-variable material layer is, If it is below the glass transition temperature, The peel strength of the above rigid-variable material layer is 150 N / m or more, The adhesive strength of the above rigid-variable material layer is 215 kPa or more, Adhesive patch.

8. In paragraph 1, The above rigid-variable material layer and the above flexible material layer are, respectively, A composition comprising at least one polymer selected from the group consisting of polyurethane, polyamide, epoxy, olefin, polysiloxane, polycarbonate or a block copolymer thereof, polydimethylsiloxane, lauryl methacrylate, stearyl acrylate, polycaprolactone, polyurethane acrylate, polyvinyl chloride, polyethylene glycol dimethacrylate, tertbutyl acrylate, stearyl methacrylate, polyimide, polyethylene glycol diacrylate, acrylic acid and chitosan. Adhesive patch.

9. In paragraph 1, The spacing of the above segments is 0.2 mm to 1 mm, The aspect ratio of the above segment is 1:1 to 1:4, Adhesive patch.

10. In paragraph 1, Based on 100 parts by weight of the above adhesive patch, The above rigid-variable material layer is 60 to 70 parts by weight, The above flexible material layer is 30 to 40 parts by weight, Adhesive patch.

11. In paragraph 1, When the glass transition temperature of the above rigid-variable material layer is lower than that of the above rigid-variable material layer, the peel strength ratio of the above rigid-variable material layer and the above flexible material layer is 1:1 to 30:

1. Adhesive patch.

12. In paragraph 1, In the cross section of the above adhesive patch, The total area ratio of the above rigid-variable material layer and the above flexible material layer is 1:0.5 to 1:

8. Adhesive patch.

13. Including the adhesive patch of paragraph 1, A medical device that can be attached to the skin.

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