Configuration applied to transcranial photobiomodulation equipment

Abstract

The present application relates to equipment for transcranial photobiomodulation (t-PBM) comprising a rigid structure in the form of a helmet (1), which covers the majority of the external cranial region, and light sources (2) emitting in the infrared spectrum, at a wavelength of 810 nm, thereby defining a total or partial, multifocal, focal, or superfocal irradiation device, the assembly further comprising a control panel (3) with an LCD display and being powered by an energy source (4) connected both to the control panel (3) and the helmet (1) by means of a Y-cable (5), or, in a wireless version, a wireless transmitter replaces the Y-cable, and the energy source is coupled to the helmet, and an application for mobile devices replaces the control panel. The equipment according to the present application utilises the concept of transcranial photobiomodulation, with light sources emitting in the infrared region, aimed at adjuvant treatment of central nervous system (CNS) diseases. The assembly aims to produce a biomodulatory effect in a non-invasive and non-thermal manner, in the cerebral region.

Description

[0001] CONFIGURATION APPLIED TO TRANSCRANIAL PHOTOBIOMODULATION EQUIPMENT

[0002] FIELD OF APPLICATION

[0003]

[0001] The present application utilizes the concept of transcranial photobiomodulation (t-PBM) with a light source emitting in the infrared range of 810 nm, aiming for use in adjuvant therapy for CNS (central nervous system) diseases.

[0004] BACKGROUND

[0005]

[0002] Transcranial photobiomodulation is a safe and non-invasive therapy that uses light to stimulate the brain. t-PBM can be performed with a near-infrared laser or with red and infrared LED lights. The light induces a photochemical process that stimulates the production of energy in the form of ATP, mainly in the mitochondria. Being a non-invasive method, the procedure is comfortable for users and can be performed in clinics or in the user's own home, under professional guidance.

[0006]

[0003] Several approaches aimed at providing devices for transcranial photobiomodulation are known in the state of the art.

[0007]

[0004] For example, document US10632325 discloses a portable, non-invasive system, apparatus and method for performing light therapy or photobiomodulation on brain tissue through the skull and / or nostrils of a live mammal for the medical purpose of stimulating the brain in vivo. The invention utilizes transcranial and / or intranasal pathways as anatomical access points and follows established principles for the conceptual approach that irradiation of brain tissue with low levels of light energy of certain fixed parameters would achieve significant therapeutic effects in vivo.

[0005] Document BR112020002987 discloses a light therapy device in which light is distributed to the skin via one or more optical fibers at therapeutic dosages of the light source at wavelengths of 614-624nm, 668-684nm, 751-772nm and 813-846nm.The light source may consist of one or more light-emitting diodes (LEDs) arranged on a flexible printed circuit board (PCB) and a probe adapter assembly configured to deliver light to the patient's skin directly from the light source located on the PCB adjacent to the scalp surface. A control circuit operationally connected to the printed circuit board is adapted to provide power to one or more LED zones to treat hair loss, including patchy baldness, hairline baldness, and full scalp surface therapy.

[0008]

[0006] Document BR112018001857 also discloses light-modulated therapeutic devices for the treatment of dermatological disorders of the scalp. One embodiment includes a flexible printed circuit board (FPCB) supporting at least one light-emitting device having an emitter height. The FPCB includes multiple interconnected panels and defined bending regions in and between at least some of the interconnected panels in order to allow the FPCB to be configured in a concave shape to cover at least a portion of a patient's cranial vertex. At least one light-transmissive layer adjacent to the FPCB is configured to transmit light emissions (e.g., incoherent) generated by at least one light-emitting device. At least one separator is configured to be disposed between the FPCB and the patient's scalp, wherein the at least one separator includes a separator height that exceeds the emitter height.

[0009]

[0007] Document BR202015016450 reveals a programmable, portable, battery-powered, home-use device with built-in safety devices and stimulation and usage parameters programmed only by the physician or professional responsible for the patient through connection to a personal computer and use of specially developed software and stimulation method. The equipment and method are intended for the treatment of various pathologies using the neuromodulation technique via the application of electrical stimuli to electrodes positioned in a customized cap.

[0010]

[0008] Finally, document BR102017002705 discloses a device for transcranial biomodulation developed with the aim of biomodulating the brain activity of patients affected by neurodegenerative diseases and other brain dysfunctions, with the aid of radiation emitted by LEDs, the device comprising a rigid structure that covers most of the external cranial region, with independently activated sections, defining a segmented irradiation device emitting visible and / or infrared radiation, in addition to a device with a single segment fully activated, defining a total irradiation device.

[0011]

[0009] It is clear that, in the current state of the art, there is a demand for different solutions involving devices for transcranial photobiomodulation.

[0012] SUMMARY

[0013]

[0010] The present model refers to a transcranial photobiomodulation helmet set comprising, in addition to the helmet itself, a control panel, a power source and a Y-cable, indicated for an adjuvant approach to CNS (central nervous system) diseases. The present model also includes a “wireless” version containing the helmet itself, which has a battery that allows its use without the need to be connected to electricity, and a wireless transmitter and receiver controlled by a mobile application.

[0011] The helmet body comprises light sources, emitting light in the infrared spectrum, in the wavelength range of 810 nm, geometrically spaced so as to reach the entire cerebral cortex, providing multifocal incidence of this radiation.

[0014]

[0012] This model can be activated in 3 ways:

[0015] 1 - MULTIFOCAL: activated in full mode to reach the entire cerebral cortex.

[0016] 2 - FOCAL: activated parts of the device to isolate the area(s) of the Cortex: Frontal, Parietal, Occipital and Temporal.

[0017] 3 - SUPER FOCAL: Individualizes the activation of each LED to be applied to specific regions, acting like a needle of light.

[0018] BRIEF DESCRIPTION OF THE DRAWINGS

[0019]

[0013] Figure 1 illustrates the first embodiment of the transcranial photobiomodulation helmet assembly according to the present application.

[0020]

[0014] Figure 2 is an exploded view of the transcranial photobiomodulation helmet according to the present application.

[0021]

[0015] Figure 3 illustrates the second, modality of the transcranial photobiomodulation helmet assembly according to the present application.

[0022] DETAILED DESCRIPTION

[0023]

[0016] This application refers to a transcranial photobiomodulation helmet set which performs, through infrared radiation emitting elements, suitably positioned in a helmet (1) customizable for better adjustment to the user's skull - in contact with the patient's scalp, photobiomodulation, aiming at adjuvant treatment of various pathologies.

[0024]

[0017] The equipment can be configured to generate stimuli and is an equipment that uses transcranial photobiomodulation (t-PBM) technology with LEDs that radiate light in the infrared wavelength range of 810nm (2) uniformly distributed, for the adjuvant treatment of CNS (central nervous system) diseases. The equipment can be programmed by a responsible physician or qualified and trained healthcare professional. The user interface is simple and straightforward, consisting of a control panel (3) with an LCD display. Therefore, the set according to the present application is intrinsically much safer and also allows its easy and correct use by the user in their own home, with medical supervision or by a qualified and trained healthcare professional.This monitoring can be done in person or through telemedicine (online / virtual guidance). The unit is powered by a power source (4) connected to both the control panel (3) and the helmet (1) itself, via a Y cable (5).

[0025]

[0018] In a first embodiment, the assembly according to the present application operates with connection via cables, power supply and control panel, as follows:

[0026] SOURCE:

[0027] Input: 100-240V~50 / 60Hz 1.5A 70VA

[0028] Output: 5Vdc, 6A, 30W

[0029] Fuyuang Equipment, Model: FY0506000

[0030] CABLE:

[0031] Y-cable coated with PVC and M12 type connectors with 5 pins, M12 type female connector with 8 pins and male power connector.

[0032] PANEL:

[0033] Control panel Firmware 1.0 with two independent channels, intensity modulators with 4 stages, timer from 1 to 30 minutes and frequency selection from 1 to 20,000Hz

[0019] In a second embodiment, the assembly according to the present application operates with wireless connection, as follows:

[0034]

[0020] In this version, the power supply, Y-cable and panel elements are replaced by an app and battery located in the helmet.

[0035]

[0021] The helmet is controlled by a wireless mobile app. It has a battery that allows it to be used without needing to be plugged into an electrical outlet.

[0036]

[0022] As illustrated in FIGS. 1 and 3, the device according to this application allows irradiation with infrared LEDs throughout the cranial vault, activating all brain regions. Functionally, the model according to this application activates the set of LEDs arranged on the surface of the cranial vault, covering the regions responsible for brain activity, such as the frontal, parietal, occipital, and temporal lobes, resulting in a model that irradiates the entire cranial vault, i.e., the entire brain region is stimulated in a multifocal or focal manner.

[0037]

[0023] The helmet (1) comprises 256 LED units, 60mW power supply per LED unit, with irradiance of 45mW / cm2, power of 24mW / cm2, energy density of 4 to 10 J / cm2, LED pulse frequency of 1 Hz to 20,000 Hz, timer of 1-30 minutes ± 2min and intensity of 25%, 50%, 75% and 100%. In terms of operating conditions, the device according to the present application preferably operates between 10°C and 24°C and with a relative humidity of 30% to 80%.

[0038]

[0024] The present application has been described with reference to two preferred embodiments, but it will be apparent to those skilled in the art that other modifications may be made herein, including with regard to the use of varying raw materials and dimensions, without departing from the spirit and scope of the present application, as set forth in the following claim.

Claims

CLAIM 1. Transcranial photobiomodulation set characterized by comprising a rigid helmet-shaped structure (1), which covers most of the external cranial region, with sections activated totally or partially and equally spaced, comprising light sources (2) emitting in the infrared range of 810 nm, defining a total or partial irradiation device, multifocal, focal or superfocal, the set also comprising a control panel (3) with an LCD display and wherein the set is powered by a power source (4) connected both to the control panel (3) and to the helmet (1) by means of a Y cable (5).

2. Assembly, according to claim 1, characterized by operating in a wireless version, wherein a wireless transmitter replaces the Y-cable, and the power source is a power supply coupled to the helmet, and wherein the assembly incorporates a mobile device application that replaces the control panel.

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