Digital treatment method, system, and computer program for providing cognitive training according to cognitive function level in order to alleviate mild cognitive impairment

Abstract

Disclosed are a digital treatment method, system, and computer program for providing cognitive training according to cognitive function level in order to alleviate mild cognitive impairment. The digital treatment method comprises the steps of: selecting a cognitive function level as any one major category level among major category levels including three steps according to an external cognitive function test analysis result and storing the selected major category level in a cognitive training providing device; selecting the lowest sub-level among sub-levels constituting the selected major category level; transmitting cognitive training information corresponding to the selected sub-level to a user terminal and displaying same thereon; determining whether to adjust a sub-level of a cognitive function according to a result of analyzing cognitive training result information when the cognitive training result information is received by the cognitive training providing device; and until a training period ends, repeating the displaying of the cognitive training information corresponding to the selected sub-level and the determining of whether to adjust the sub-level of the cognitive function.

Description

Digital therapeutic methods, systems, and computer programs that provide cognitive training tailored to cognitive function levels to improve mild cognitive impairment

[0001] The present invention relates to a digital therapeutic method, system, and computer program that provides cognitive training according to cognitive function levels for the improvement of mild cognitive impairment. More specifically, the invention relates to a digital therapeutic method, system, and computer program that evaluates the degree of cognitive impairment of a patient with mild cognitive impairment and enables training tailored to the level of cognitive function.

[0002] Mild Cognitive Impairment (MCI) refers to a mild form of cognitive impairment, where cognitive impairment signifies a disorder of cognitive function. Cognitive function is broadly classified into five categories: attention, verbal function, visuospatial function, memory, and frontal lobe / executive function. The progression of MCI varies depending on which of these cognitive functions declines. Among the five types of cognitive impairment, memory has the greatest correlation with the prognosis of MCI, and specifically, verbal memory has an even greater correlation with the prognosis.

[0003] Therefore, classifying levels by evaluating the severity of mild cognitive impairment based on verbal memory is suitable for assessing the patient's prognosis. Furthermore, if cognitive training is conducted in a manner unsuitable for the individual's level, the effectiveness of the training may be diminished. For example, if a person with cognitive function at the level of a sixth grader is provided with education at the first grade level, they will find it boring, and if provided with education at the level of a third-year high school student, they will lose interest. Thus, for appropriate training, it is necessary to classify levels according to cognitive ability and objectively evaluate cognitive function by comparing these levels.

[0004] Furthermore, in the case of mild cognitive impairment, there are limitations in measuring the degree of cognitive function using digital devices due to a lack of digital biomarkers. Therefore, evaluating the effectiveness of digital therapeutic devices is limited by the need to combine them with existing brain imaging or cognitive function assessments. Since it takes at least one year for these existing evaluation methods to change, it is difficult to assess the patient's condition in a timely manner; thus, the development of digital biomarkers for the use of digital therapeutic devices is now required.

[0005] Accordingly, the objective of the present invention is to provide a digital therapeutic method, system, and computer program for providing cognitive training according to cognitive function levels to improve mild cognitive impairment, which enables cognitive training tailored to the degree of cognitive impairment by repeating the process of adjusting the cognitive function level according to the results of cognitive training and providing cognitive training tailored to the cognitive function level.

[0006] To achieve the objectives of the present invention as described above, the digital treatment method of the present invention comprises: (a) a step in which a cognitive function level is selected as one of three major classification levels based on the results of an external cognitive function test analysis and stored in a cognitive training providing device; (b) a step in which the lowest detailed level among the detailed levels constituting the selected major classification level is selected; (c) a step in which cognitive training information corresponding to the selected detailed level is transmitted to and displayed on a user terminal; (d) a step in which, when cognitive training result information is received by the cognitive training providing device, whether to adjust the detailed level of cognitive function based on the results of analyzing the cognitive training result information is determined; and (e) a step in which steps (c) and (d) are repeated until the training period ends.

[0007] The above cognitive training information is characterized by including at least one of brain training information for performing brain training and physical training information for performing physical training.

[0008] Herein, the above step (d) is characterized by including: a step of analyzing the brain training result information when the brain training result information regarding the brain training information is received by the cognitive training providing device; a step of adjusting the detailed cognitive function level upward when the daily correct answer rate is 80% or higher as a result of analyzing the brain training result information; a step of adjusting the detailed cognitive function level downward when the daily correct answer rate is less than 80% and the average correct answer rate over the past 3 days is 50% or lower; and a step of maintaining the detailed cognitive function level at its current state when the daily correct answer rate is less than 80% and the average correct answer rate over the past 3 days is greater than 50%.

[0009] Alternatively, the above step (d) is characterized by comprising: a step of analyzing the physical training result information when the physical training result information regarding the physical training information is received by the cognitive training providing device; a step of adjusting the detailed cognitive function level upward when the target exercise distance and target exercise time are satisfied as a result of the analysis of the physical training result information; a step of maintaining the detailed cognitive function level at its current state when only one of the target exercise distance and the target exercise time is satisfied; and a step of adjusting the detailed cognitive function level downward when the target exercise distance and the target exercise time are not satisfied.

[0010] The brain training information includes story memorization problems for training memory and therapeutic agents for stimulating any one of visuospatial ability, attention, executive function, language ability, and calculation ability, and the brain training information is characterized by being provided such that the number of therapeutic agents and story memorization problems varies according to the detailed level of the cognitive function.

[0011] The above physical training information is characterized by being provided such that the target speed, target exercise distance, and target exercise time vary according to the above cognitive function level.

[0012] The above external cognitive function test analysis results are characterized by including at least one analysis result among the MMSE (Mini Mental State Examination) analysis results, physical fitness evaluation, and survey analysis results.

[0013] Meanwhile, as a computer program stored on a computer-readable medium, when the computer program is executed on at least one processor of a device, it performs steps for providing cognitive training according to a cognitive function level, wherein the steps include: (a) a step in which a cognitive function level is selected as one of three major classification levels based on the results of an external cognitive function test analysis and stored in a cognitive training providing device; (b) a step in which the lowest detailed level among the detailed levels constituting the selected major classification level is selected; (c) a step in which cognitive training information corresponding to the selected detailed level is transmitted to and displayed on a user terminal; (d) a step in which, when cognitive training result information is received by the cognitive training providing device, whether to adjust the detailed level of cognitive function based on the results of analyzing the cognitive training result information is determined; and (e) a step in which steps (c) and (d) are repeated until the training period ends.

[0014] And in a digital therapeutic system that provides cognitive training according to cognitive function levels, the digital therapeutic system comprises: a cognitive training providing device that selects the lowest detailed level among the detailed levels constituting the selected major category level when one of the major category levels consisting of three stages of cognitive function levels is selected and stored according to the analysis results of an external cognitive function test; and a user terminal that receives and displays cognitive training information corresponding to the detailed level selected from the cognitive training providing device; wherein the cognitive training providing device determines whether to adjust the detailed level of cognitive function according to the results of analyzing the cognitive training result information when cognitive training result information is received from the user terminal, and repeats the process of transmitting the cognitive training information to the user terminal and receiving and analyzing the cognitive training result information from the user terminal until the training period ends.

[0015] Through the digital treatment method, system, and computer program of the present invention that provides cognitive training according to the level of cognitive function for the improvement of mild cognitive impairment, appropriate stimulation suitable for the level of cognitive function is provided, thereby allowing brain training and physical training to be performed, so that a therapeutic effect for mild cognitive impairment can be expected.

[0016] In addition, by utilizing detailed levels of cognitive function as digital biomarkers, the condition of patients with mild cognitive impairment can be objectively evaluated, and trends in cognitive function over time can be tracked.

[0017] FIG. 1 is a diagram briefly showing the configuration of a digital treatment system according to all embodiments of the present invention.

[0018] FIG. 2 is a flowchart illustrating a method for providing cognitive training in a digital therapeutic system according to all embodiments of the present invention,

[0019] FIGS. 3a to 4b are drawings illustrating a cognitive training application implemented in a digital therapeutic system according to a first embodiment of the present invention.

[0020] FIG. 5 is a flowchart illustrating a method for providing brain training in a digital therapeutic system according to a first embodiment of the present invention,

[0021] FIG. 6 is a diagram illustrating a cognitive training application implemented in a digital therapeutic system according to a second embodiment of the present invention, and

[0022] FIG. 7 is a flowchart illustrating a method for providing physical training in a digital therapeutic system according to a second embodiment of the present invention.

[0023] Hereinafter, a digital treatment method, system, and computer program (hereinafter referred to as the "digital treatment method, digital treatment system, and computer program") for providing cognitive training according to cognitive function levels to improve mild cognitive impairment according to a preferred embodiment of the present invention will be described in detail with reference to the attached drawings.

[0024] FIG. 1 is a diagram briefly illustrating the configuration of a digital treatment system according to all embodiments of the present invention.

[0025] Referring to FIG. 1, the digital therapeutic system of the present invention includes a cognitive training providing device (100) and a user terminal (200) that provide cognitive training according to cognitive function levels for the improvement of mild cognitive impairment. The cognitive training providing device (100) and the user terminal (200) are connected via a wired / wireless network (300) to transmit and receive data. The wired / wireless network (300) is a general term for a communication network that supports various communication standards or protocols for pairing or data transmission and reception between the cognitive training providing device (100) and the user terminal (200). Such a wired / wireless network (300) includes all communication networks currently or to be supported in the future according to the standards, and can support all one or more communication protocols for that purpose.

[0026] The cognitive training providing device (100) may be any device capable of transmitting or receiving data, contents, services, and applications. In the present invention, the cognitive training providing device (100) refers to a server, but is not limited thereto; it may also refer to a fixed device such as a PC (Personal Computer) or a mobile device such as a smartphone, tablet PC, or notebook, and unless specifically mentioned otherwise, it may be used to include all of them.

[0027] Here, a server refers to a device or system that transmits data to or receives data from various types of user terminals, namely clients. Examples of servers may include a web server or portal server that provides web pages, web content or web services, an advertising server that provides advertising data, a content server that provides content, a social network service (SNS) server that provides SNS, a service server provided by a manufacturer, a multichannel video programming distributor (MVPD) for providing video on demand (VoD) or streaming services, a service server that provides paid services, etc.

[0028] Meanwhile, the user terminal (200) of the present invention is connected to the cognitive training providing device (100) to transmit, receive, and display predetermined data. The user terminal (200) may be implemented as a mobile terminal such as a mobile phone, a smartphone, a tablet PC, an ultrabook, etc. However, it is not limited thereto and may also include a fixed device such as a PC (Personal Computer), a microprocessor, a mainframe computer, a digital processor, a device controller, etc.

[0029] A cognitive training application for providing cognitive training according to the cognitive function level is executed on the user terminal (200), and the user receives cognitive training information through the cognitive training application. The cognitive training information includes brain training information for performing brain training and physical training information for performing physical training.

[0030] For brain training, story memorization problems are provided to train memory, along with therapeutic drugs to stimulate cognitive abilities other than memory. Cognitive abilities other than memory include visuospatial ability, attention, executive function, language ability, and calculation ability. The number of story memorization problems and therapeutic drugs varies depending on the level of cognitive function.

[0031] For physical training, exercise speed, distance, and time are measured through a cognitive training application, and the target exercise speed, distance, and time vary according to the cognitive function level.

[0032] The cognitive training providing device (100) of the present invention includes a first storage unit (110), a first processor (120), and a first communication unit (130). Each component may be integrated, added, or omitted according to the specifications of the cognitive training providing device (100) actually implemented. That is, as needed, two or more components may be combined into one component, or one component may be subdivided into two or more components. Furthermore, the functions performed in each block are intended to explain embodiments of the present invention, and the specific operations or devices thereof do not limit the scope of the rights of the present invention.

[0033] The first storage unit (110) can store data that supports various functions of the cognitive training provider (100). That is, the first storage unit (110) can store a number of applications running on the cognitive training provider (100), data for the operation of the cognitive training provider (100), commands, and at least one program command. At least some of these applications may exist on the cognitive training provider (100) from the time of shipment for the basic functions of the cognitive training provider (100), or may be downloaded from an external server via wireless communication.

[0034] In the present invention, a cognitive training application is stored in the first storage unit (110), and cognitive training information corresponding to cognitive function levels and each level is stored. Here, the cognitive function level is classified into three major classification levels consisting of upper, middle, and lower stages, and each major classification level is further classified into multiple detailed levels. The 'upper' level is a state of high cognitive function, and the 'lower' level is a state of low cognitive function. In the case of detailed levels, the smaller the number, the lower the cognitive function.

[0035] As exemplified in [Table 1] below, brain training information corresponding to each detailed level is stored in the first storage unit (110).

[0036] [Table 1]

[0037]

[0038] In addition, as exemplified in [Table 2] below, physical training information corresponding to each detailed level is stored in the first storage unit (110).

[0039] [Table 2]

[0040]

[0041] The detailed cognitive function levels shown in Tables 1 and 2 function as digital biomarkers that can objectively represent the condition of patients with mild cognitive impairment, and the detailed cognitive function levels for brain training and the detailed cognitive function levels for physical training can also be represented as integrated detailed levels for cognitive training that integrate brain training and physical training through [Equation 1] below.

[0042] [Mathematical Formula 1]

[0043]

[0044] In [Mathematical Formula 1], A is the integrated detailed level, B is the cognitive function detailed level for physical training, and C is the cognitive function detailed level for brain training.

[0045] For example, if the cognitive function detailed level for physical training is level 3 and the cognitive function detailed level for brain training is level 5, calculating through [Mathematical Formula 1] results in the rounded value of (3+5*2) / 3, which is '4', and the integrated detailed level becomes level 4.

[0046] Each detailed level is utilized as a digital biomarker, serving as a means to objectively evaluate the condition of patients with mild cognitive impairment.

[0047] And, cognitive training result information transmitted from the user terminal (200) is stored in the first storage unit (110). The cognitive training result information includes brain training result information and physical training result information. The cognitive training application stored in the first storage unit (110) is transmitted to and installed on the user terminal (200) via a wired / wireless network (300). The brain training result information and physical training result information stored in the first storage unit (110) are analyzed by the first processor (120) described later.

[0048] The first processor (120) can control the overall operation of the cognitive training provider (100) and can provide or process appropriate information or functions by processing signals, data, information, etc. that are input or output through the components of the cognitive training provider (100) or by running an application program stored in the first storage unit (110). In addition, the first processor (120) can control at least some of the components of the cognitive training provider (100) to run an application program stored in the first storage unit (110). Furthermore, the first processor (120) can operate at least two or more of the components included in the cognitive training provider (100) in combination with each other to run an application program.

[0049] The first processor (120) may be composed of one or more cores and may be any of the various commercial processors. For example, the first processor (120) may include the device's Central Processing Unit (CPU), General Purpose Graphics Processing Unit (GPUGP), Tensor Processing Unit (TPU), etc. Additionally, the first processor (120) may be composed of a dual processor or other multi-processor architecture.

[0050] In the present invention, the first processor (120) analyzes the cognitive training result information stored in the first storage unit (110) and determines whether to adjust the detailed level of the cognitive function.

[0051] To explain in more detail, the first processor (120) analyzes the daily brain training result information to determine whether to adjust the detailed level of cognitive function. That is, if the daily accuracy rate for the brain training information submitted on that day is 80% or higher, the detailed level of cognitive function is adjusted upward. If the daily accuracy rate is less than 80% and the average accuracy rate over the past 3 days is 50% or lower, the detailed level of cognitive function is adjusted downward. If the daily accuracy rate is less than 80% and the average accuracy rate over the past 3 days is greater than 50%, the detailed level of cognitive function is maintained at its current state.

[0052] Additionally, the first processor (120) analyzes the physical training result information for one week to determine whether to adjust the detailed level of cognitive function. That is, if the distance and time exercised at the target exercise speed corresponding to the selected detailed level satisfy the target exercise distance and target exercise time corresponding to the selected detailed level, the cognitive function level is adjusted upward. If only one of the target exercise distance and target exercise time is satisfied, the cognitive function level is maintained at its current state. If the target exercise distance and target exercise time are not satisfied, the cognitive function level is adjusted downward.

[0053] The first communication unit (130) may include one or more modules that enable wired / wireless communication between the cognitive training provider (100) and a wired / wireless network (300), between the cognitive training provider (100) and another device, or between the cognitive training provider (100) and an external server. Additionally, the first communication unit (130) may include one or more modules that connect the cognitive training provider (100) to one or more networks. Furthermore, the first communication unit (130) refers to a module for connecting to a wired / wireless network (300), which may be embedded in or externally mounted on the cognitive training provider (100) and configured to transmit and receive wired / wireless signals.

[0054] In the present invention, the first communication unit (130) transmits a cognitive training application to a user terminal (200) so that it is installed on the user terminal (200). In addition, it transmits cognitive training information corresponding to a detailed level of cognitive function selected by the first processor (120) to the user terminal (200) and receives cognitive training result information from the user terminal (200).

[0055] Meanwhile, the user terminal (200) of the present invention can be paired or connected with the cognitive training providing device (100) via a wired / wireless network (300), and can transmit, receive, and display certain data through this. The user terminal (200) includes a second storage unit (210), a second processor (220), a second communication unit (230), a user interface unit (240), a shooting unit (250), a speaker (260), and a sensor unit (270).

[0056] Each component may be integrated, added, or omitted according to the specifications of the actual user terminal (200) being implemented. That is, as needed, two or more components may be combined into one component, or one component may be subdivided into two or more components. In addition, the functions performed in each block are intended to explain the embodiments of the present disclosure, and the specific operations or devices thereof do not limit the scope of the present invention.

[0057] The second storage unit (210) stores a cognitive training application downloaded from the cognitive training providing device (100) and cognitive training information provided by the cognitive training providing device (100). The cognitive training information stored in the second storage unit (210) includes brain training information and physical training information corresponding to a detailed level selected by the first processor (120).

[0058] The second processor (220) executes a cognitive training application stored in the second storage unit (210) and controls the cognitive training information to be displayed through the user interface unit (240) described later. That is, it processes the brain training information and physical training information provided by the cognitive training providing device (100) so that they are displayed through the user interface unit (240).

[0059] Additionally, the second processor (220) controls the generation of cognitive training result information and transmission to the cognitive training providing device (100). That is, it controls the generation of brain training result information and transmission to the cognitive training providing device (100) according to user commands input through the user interface unit (240). It also controls the generation of physical training result information and transmission to the cognitive training providing device (100) according to the movement speed, movement distance, and movement time detected through the sensor unit (270) described later. At this time, the second processor (220) measures the target distance and target time when moving at the target speed included in the physical training information corresponding to the selected detailed level.

[0060] The second communication unit (230) communicates with the cognitive training providing device (100) through a wired / wireless network (300), receives cognitive training applications and cognitive training information transmitted from the cognitive training providing device (100), and transmits cognitive training result information generated by the second processor (220) to the cognitive training providing device (100).

[0061] The user interface unit (240) is configured to include a display unit that displays information processed by the user terminal (200) and an input unit that receives user commands by implementing a key or touch method. Through the user interface unit (240), information on the execution screen of an application running on the user terminal (200) or UI (User Interface) and GUI (Graphic User Interface) information corresponding to the execution screen information is displayed. Through the user interface unit (240), the user can input desired commands or information when executing a cognitive training application.

[0062] The shooting unit (250) may include one or more cameras. That is, the user terminal (200) includes one or more cameras on at least one side of the front or rear. The shooting unit (250) can process image frames, such as still images or video, obtained by an image sensor. The processed image frames may be displayed on the display unit (250) or stored in the second storage unit (210).

[0063] The speaker (260) outputs audio data received through the second communication unit (230) or stored in the second storage unit (210). Additionally, the speaker (260) outputs audio data related to functions performed on the user terminal (200). In the present invention, the speaker (260) outputs audio data related to the execution of a cognitive training application.

[0064] The sensor unit (270) includes an acceleration sensor that detects the movement speed of the user terminal (200) and a position sensor that detects the distance traveled. The sensor unit (270) detects the movement speed and distance traveled of the user terminal (200) when the user performs physical training. The second processor (220) measures the distance traveled and the travel time while the movement speed is greater than or equal to the target speed.

[0065] FIG. 2 is a flowchart illustrating a method for providing cognitive training in a digital therapeutic system according to all embodiments of the present invention.

[0066] First, according to FIG. 2, based on the analysis results of an external cognitive function test, the cognitive function level is selected as one of three major classification levels and stored in the cognitive training providing device (100) (S400). The external cognitive function test includes the Mini Mental State Examination (MMSE) to test brain activity and a physical fitness assessment and questionnaire to test physical activity. Based on the analysis results of the external cognitive function test, the cognitive function level is classified into one of three levels—high, medium, or low—and stored in the cognitive training providing device (100).

[0067] Then, the lowest level among the detailed levels constituting the selected major category level is selected (S410). Referring to [Table 1] and [Table 2], for example, when the 'High' level is selected, the lowest level among the detailed levels, Level 9, is selected; when the 'Middle' level is selected, the lowest level among the detailed levels, Level 5, is selected; and when the 'Low' level is selected, the lowest level among the detailed levels, Level 1, is selected.

[0068] Cognitive training information corresponding to the selected detailed level is transmitted to and displayed on the user terminal (S420). For example, if brain training is provided through the digital treatment system of the present invention and the cognitive function level is classified as 'high' level, then level 9, which is the lowest level of the 'high' level, is selected, and '4 sets (9 story memorization problems, 10 medicines)' corresponding to level 9 are transmitted to and displayed on the user terminal.

[0069] When cognitive training result information is received (S430-Y), the cognitive training providing device (100) determines whether to adjust the detailed level of the cognitive function based on the result of analyzing the cognitive training result information (S440). That is, cognitive training result information is generated at the user terminal (200), transmitted to the cognitive training providing device (100) for analysis, and based on the analysis result, the detailed level of the cognitive function is adjusted upward or downward, or the current state is maintained.

[0070] Steps S420 to S440 are repeated until the training period ends (S450). That is, brain training information or physical training information corresponding to the selected detailed level is transmitted to and displayed on the user terminal (200), and when brain training result information or physical training result information is generated at the user terminal (200) and transmitted to the cognitive training providing device (100), the cognitive training providing device (100) analyzes the brain training result information or physical training result information and repeats the process of adjusting the detailed level of cognitive function upward or downward, or maintaining the current state, until the training period ends.

[0071] FIGS. 3a to 4b are drawings illustrating a cognitive training application implemented in a digital therapeutic system according to a first embodiment of the present invention.

[0072] FIGS. 3a and 3b illustrate a cognitive training application that provides story memorization problems for training memory as brain training information. As shown in FIG. 3a, the user clicks 'Brain Activity 1' in the cognitive training application provided through the user interface unit (240) to play a story of about 3 minutes. Then, as shown in FIG. 3b, the user is allowed to recall and remember the story by solving the first quiz related to the played story. After that, the user is allowed to play a brain stimulation game for about 20 minutes and then solve a second quiz related to the played story to recall the memory related to the played story once again. At this time, the answer to the second quiz submitted after 20 minutes is generated as brain training result information and analyzed by the cognitive training providing device (100).

[0073] Figure 4a illustrates a cognitive training application that provides a therapeutic agent to stimulate calculation skills as brain training information. In addition to the 'shape calculation' exemplified in Figure 4a, the therapeutic agent to stimulate calculation skills includes general calculation problems.

[0074] Figure 4b illustrates a cognitive training application that provides brain training information as a therapeutic agent to stimulate spatiotemporal abilities. In addition to 'matching the number of blocks' exemplified in Figure 4b, the therapeutic agents to stimulate spatiotemporal abilities include 'choosing different shapes', 'shape rotation', 'shape with different colored positions', 'matching three-dimensional rings', 'dice planar diagrams', and 'matching the positions of colors on a plane'.

[0075] In addition to this, cognitive training applications can provide "medications" to stimulate attention, executive function, and language ability. Medications to stimulate attention include "writing proverbs backward," "choosing the different letter," and "finding the differences." Medications to stimulate executive function include "finding based on clues," "finding the person facing you," and "lining up." Medications to stimulate language ability include "inverted four-character idioms," "speed quizzes," "word chain games," and "word chain games starting with a specific letter."

[0076] FIG. 5 is a flowchart illustrating a method for providing brain training in a digital therapeutic system according to a first embodiment of the present invention.

[0077] According to Fig. 5, based on the results of the Mini Mental State Examination (MMSE) analysis, the cognitive function level is selected as one of three major classification levels and stored in the cognitive training providing device (100) (S500). The MMSE is a test tool for evaluating cognitive function simply in a short period of time, and generally, a total score of 23 points is set as the evaluation standard for cognitive impairment.

[0078] Among the detailed levels constituting the selected major category level, the lowest detailed level is selected (S510). Then, brain training information corresponding to the selected detailed level is transmitted to and displayed on the user terminal (200) (S520). For example, referring to [Table 1], the cognitive function of the MMSE analysis result is selected as the 'Medium' level, and Level 5, which is the lowest level of the 'Medium' level, is selected as the detailed level. Then, '4 sets of (7 story memorization problems, 10 medicines)', which is brain training information corresponding to Level 5, is transmitted to and displayed on the user terminal (200).

[0079] When brain training result information is received (S530-Y), the brain training result information is analyzed in the cognitive training providing device (100) (S540). That is, when answer information for '(7 story memorization problems, 10 medicines) 4 sets' displayed on the user terminal (200) is entered, brain training result information is generated in the user terminal (200), and the brain training result information is transmitted to the cognitive training providing device (100) for analysis.

[0080] When the brain training result information analysis shows that the daily accuracy rate is 80% or higher (S550-Y), the cognitive function detailed level is adjusted upward (S555). That is, the cognitive function detailed level is adjusted upward to level 6, and on the next day, 3 sets of brain training information corresponding to detailed level 6, such as '(7 story memorization problems, 20 medicines)', are transmitted to and displayed on the user terminal (200).

[0081] If the accuracy rate on the day is less than 80% (S550-N) and the average accuracy rate over the past 3 days is 50% or less (S560-Y), the cognitive function detailed level is lowered. That is, the cognitive function detailed level is lowered to level 4, and on the next day, brain training information corresponding to detailed level 4, '(5 story memorization problems, 40 medicines)', is transmitted to and displayed on the user terminal (200).

[0082] If the accuracy rate for the day is less than 80% (S550-N) and the average accuracy rate for the last 3 days is greater than 50% (S560-N), the cognitive function detailed level is maintained in its current state. That is, the cognitive function detailed level is maintained at level 5, and on the next day, brain training information corresponding to detailed level 5, such as '(7 story memorization problems, 10 medicines) 4 sets', is transmitted to and displayed on the user terminal (200).

[0083] The detailed levels determined through steps S550 to S570 function as digital biomarkers to objectively indicate the condition of patients with mild cognitive impairment.

[0084] If the training period has not ended (S580-N), brain training information corresponding to the detailed level is displayed on the user terminal (200), and the process of analyzing the brain training result information at the cognitive training providing device (100) to determine whether to adjust the detailed level of cognitive function is repeated.

[0085] Through the process described above, mild cognitive impairment can be improved by conducting brain training tailored to the patient's level of cognitive impairment.

[0086] FIG. 6 is a diagram illustrating a cognitive training application implemented in a digital therapeutic system according to a second embodiment of the present invention.

[0087] When 'Start walking' is selected to train the body, physical training information corresponding to the selected detailed level is displayed through the user interface section (240). For example, referring to [Table 2], physical training information corresponding to detailed level 1, such as a target speed of 4.5 km / h, a target distance of 2.0 km, and a target time of 30 minutes, is displayed through the user interface section (240). Since the current speed is also displayed, the user can adjust the movement speed to match the current speed to the target speed.

[0088] The travel distance of 0.8 km is the actual distance traveled measured and displayed at a target speed of 4.5 km / h, and the travel time of 5 minutes and 45 seconds is the actual time traveled measured and displayed at a target speed of 4.5 km / h. If the travel distance is 2.0 km or more and the travel time is 30 minutes or more, the detailed cognitive function level is adjusted upward. If the travel distance is 2.0 km or more and the travel time is less than 30 minutes, the detailed cognitive function level remains at its current state. Even if the travel distance is less than 2.0 km and the travel time is 30 minutes or more, the detailed cognitive function level remains at its current state. Furthermore, if the travel distance is less than 2.0 km and the travel time is less than 30 minutes, the detailed cognitive function level is adjusted downward.

[0089] In addition, when physical training is performed, the number of steps that are helpful for treatment is displayed through the user interface section (240). That is, the number of steps taken at a target speed of 4.5 km is detected and displayed. Also, since voice guides are provided, if necessary, one can select one of the walking training guides and receive guidance on how to adjust walking speed or how to walk correctly through voice output through the speaker.

[0090] Additionally, by clicking the camera icon (600), you can take a photo before, during, or after starting or finishing an exercise and save it as a memory diary. The memory diary includes location information of where the photo was taken, date information of when the photo was taken, and object information regarding the people or objects in the photo. The object information includes information such as the type of object, the number of people, and gender.

[0091] FIG. 7 is a flowchart illustrating a method for providing physical training in a digital therapeutic system according to a second embodiment of the present invention.

[0092] According to Fig. 7, based on the results of the physical fitness evaluation and survey analysis, one of the three major classification levels of cognitive function level is selected and stored in the cognitive training providing device (100) (S700).

[0093] Among the detailed levels constituting the selected major category level, the lowest detailed level is selected (S710). Then, physical training information corresponding to the selected detailed level is transmitted to and displayed on the user terminal (200) (S720). Referring to [Table 2], for example, the cognitive function is selected as the 'Medium' level based on the physical fitness evaluation and survey analysis results, and Level 5, which is the lowest level of the 'Medium' level, is selected as the detailed level. Then, the physical training information corresponding to Level 5, 'target speed 5 km / h, target distance 3 km, target time 35 minutes', is transmitted to and displayed on the user terminal (200).

[0094] When physical training result information is received (S730-Y), the physical training result information is analyzed in the cognitive training providing device (100) (S740). That is, the movement speed, distance traveled, and time traveled over a week are measured at the user terminal (200) to generate physical training result information, and the physical training result information is transmitted to the cognitive training providing device (100) for analysis.

[0095] When the physical training result information analysis results, if the target distance is met (S750-Y) and the target time is met (S760-Y), the cognitive function detailed level is adjusted upward (S780). That is, the cognitive function detailed level is adjusted upward to level 6, and in the next week, physical training information corresponding to detailed level 6, such as 'target speed 5 km / h, target distance 3.25 km, target time 40 minutes', is transmitted to and displayed on the user terminal (200).

[0096] If the target distance is not met (S750-N) and the target time is not met (S770-N), the cognitive function detailed level is lowered. That is, the cognitive function detailed level is lowered to level 4, and in the next week, physical training information corresponding to detailed level 4, such as 'target speed 4.5 km / h, target distance 2.75 km, target time 40 minutes', is transmitted to and displayed on the user terminal (200).

[0097] If the target distance is not met (S750-N) and the target time is met (S770-Y), the cognitive function detailed level remains in its current state. Also, even if the target distance is met (S750-Y) and the target time is not met (S770-N), the cognitive function detailed level remains in its current state. That is, the cognitive function detailed level remains at level 5, and the physical training information corresponding to detailed level 5, 'target speed 5 km / h, target distance 3 km, target time 35 minutes', is transmitted to and displayed on the user terminal (200) in the following week.

[0098] The detailed levels determined through steps S750 to S780 function as digital biomarkers to objectively indicate the condition of patients with mild cognitive impairment.

[0099] If the training period has not ended (S790-N), physical training information corresponding to the detailed level is displayed on the user terminal (200), and the process of determining whether to adjust the detailed level of cognitive function by analyzing the physical training result information in the cognitive training providing device (100) is repeated.

[0100] Through the process described above, physical training tailored to the patient's level of cognitive impairment can be conducted to improve mild cognitive impairment.

[0101] The foregoing description of the present invention is for illustrative purposes only, and those skilled in the art will understand that other specific forms can be easily modified without altering the technical spirit or essential features of the present invention. Therefore, the embodiments described above should be understood as illustrative in all respects and not restrictive. For example, each component described as a single unit may be implemented in a distributed manner, and components described as distributed may likewise be implemented in a combined form.

[0102] The scope of the present invention is defined by the claims set forth below rather than by the detailed description above, and all modifications or variations derived from the meaning and scope of the claims and equivalent concepts thereof should be interpreted as being included within the scope of the present invention.

Claims

1. A digital therapeutic method in which at least one processor of a device provides cognitive training according to a level of cognitive function for the improvement of mild cognitive impairment, (a) A step in which, based on the analysis results of an external cognitive function test, a cognitive function level is selected as one of three major classification levels and stored in a cognitive training providing device; (b) A step in which the lowest level of detail among the detailed levels constituting the selected major category level is selected; (c) A step in which cognitive training information corresponding to the selected detailed level is transmitted to and displayed on a user terminal; (d) a step in which, when cognitive training result information is received by the cognitive training providing device, whether to adjust the detailed level of cognitive function according to the result of analyzing the cognitive training result information is determined; and (e) a step in which the above (c) and above (d) steps are repeated until the training period ends; a digital treatment method characterized by including 2. In Paragraph 1, A digital therapeutic method characterized in that the above-mentioned cognitive training information includes at least one of brain training information for performing brain training and physical training information for performing physical training.

3. In Paragraph 2, The above step (d) is, When brain training result information regarding the above brain training information is received by the cognitive training providing device, a step of analyzing the brain training result information; A step in which, based on the analysis of the brain training result information, the daily accuracy rate is 80% or higher, the detailed level of the cognitive function is adjusted upward; A step in which the detailed level of cognitive function is lowered when the accuracy rate on the day is less than 80% and the average accuracy rate over the past 3 days is 50% or less; and A digital treatment method characterized by including a step in which, if the accuracy rate on the day is less than 80% and the average accuracy rate over the past 3 days is greater than 50%, the detailed level of cognitive function is maintained in its current state.

4. In Paragraph 2, The above step (d) is, When physical training result information regarding the above physical training information is received by the cognitive training providing device, a step of analyzing the physical training result information; A step in which, based on the analysis results of the physical training result information, the target exercise distance and target exercise time are satisfied, the detailed level of the cognitive function is adjusted upward; A step in which, if only one of the above target exercise distance and the above target exercise time is satisfied, the above cognitive function detailed level is maintained in the current state; and A digital treatment method characterized by including a step in which the detailed level of cognitive function is lowered when the above target exercise distance and above target exercise time are not satisfied.

5. In Paragraph 2, A digital therapeutic method characterized by the fact that the above brain training information includes story memorization problems for training memory and therapeutic drugs for stimulating any one of visuospatial ability, attention, executive function, language ability, and calculation ability.

6. In Paragraph 5, A digital treatment method characterized by the fact that the brain training information is provided such that the number of the therapeutic drugs and the story memorization problems varies according to the detailed level of the cognitive function.

7. In Paragraph 2, A digital therapeutic method characterized by providing the above physical training information such that the target speed, target exercise distance, and target exercise time vary according to the above cognitive function level.

8. In Paragraph 1, A digital treatment method characterized in that the analysis results of the external cognitive function test above include at least one analysis result among the Mini Mental State Examination (MMSE) analysis results, physical fitness evaluation, and survey analysis results.

9. A computer program stored on a computer-readable medium, wherein, when executed on at least one processor of a device, the computer program performs steps for providing cognitive training according to a level of cognitive function, said steps being: (a) A step in which, based on the analysis results of an external cognitive function test, a cognitive function level is selected as one of three major classification levels and stored in a cognitive training providing device; (b) A step in which the lowest level of detail among the detailed levels constituting the selected major category level is selected; (c) A step in which cognitive training information corresponding to the selected detailed level is transmitted to and displayed on a user terminal; (d) a step in which, when cognitive training result information is received by the cognitive training providing device, whether to adjust the detailed level of cognitive function according to the result of analyzing the cognitive training result information is determined; and (e) a step in which the above (c) and above (d) steps are repeated until the training period ends; a computer program stored on a computer-readable medium characterized by including 10. In a digital therapeutic system that provides cognitive training according to cognitive function levels, The above digital therapeutic system is: A cognitive training providing device that, when one of the major classification levels consisting of three stages of cognitive function levels is selected and stored according to the analysis results of an external cognitive function test, selects the lowest detailed level among the detailed levels constituting the selected major classification level; and A user terminal that receives and displays cognitive training information corresponding to a detailed level selected from the above-mentioned cognitive training providing device; A digital therapeutic system characterized by the above-described cognitive training providing device determining whether to adjust the detailed level of cognitive function based on the result of analyzing the cognitive training result information when cognitive training result information is received from the user terminal, and repeating the process of transmitting cognitive training information to the user terminal and receiving and analyzing cognitive training result information from the user terminal until the training period ends.

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