Compositions and methods to modulate transposable elements governing cell-state transitions

Abstract

Disclosed herein are modulators of a transposable element or a transposable element transcript, wherein the modulators induce or facilitate a cell state transition or change. Further provided herein are synthetic polynucleic acids comprising a nucleic acid sequence of a transposable element or a portion thereof, wherein the synthetic polynucleic acids induce or facilitate cell state transitions or changes. Further provided herein are methods of preventing, alleviating, or treating pulmonary fibrosis in a subject in need thereof. Further provided herein are methods of cellular reprograming and reversing aging in a pulmonary tissue. Further provided herein are methods of diagnosing or prognosing pulmonary fibrosis.

Description

Attorney Docket No. 60448-717.601COMPOSITIONS AND METHODS TO MODULATE TRANSPOSABLE ELEMENTS GOVERNING CELL-STATE TRANSITIONSCROSS REFERENCE

[0001] This application claims the benefit of U. S. Provisional Application No. 63 / 721,897, filed November 18, 2024, which is incorporated herein by reference in its entirety.BACKGROUND OF THE DISCLOSURE

[0002] Transposable elements are DNA sequences that move from one location in the genome to another. Transposable element-derived sequences expressed alone or incorporated in other RNA transcripts are thought to play a role in gene regulatory networks. However, little has been dissected out regarding their role in governing cell-state transitions, which can be dynamically associated with disease progression in numerous clinical settings.

[0003] Therefore, there is a need for a better understanding of the transposable elements that drive cell-state transition and how to modulate the expression or activity of such transposable elements to prevent or treat the disease progression or symptoms related to the cell-state transitions.SUMMARY OF THE DISCLOSURE

[0004] The present disclosure provides the identification of exemplary transposable elements that play a role in cell-state transitions and disease progression and provides compositions and methods for treating, alleviating, or preventing diseases or symptoms thereof (e.g., lung fibrosis, heart fibrosis, or dermal fibrosis) by modulating (e.g., activating, suppressing, or supplementing) the expression or activity of the transposable elements. The present disclosure also teaches methods for reprogramming myofibroblasts or evaluating or monitoring efficacy of a treatment to induce pulmonary reprogramming. The present disclosure also teaches methods for methods of slowing or reversing aging of a pulmonary tissue or evaluating or monitoring pulmonary tissue regeneration. The present disclosure also teaches methods for methods of diagnosing or prognosing pulmonary fibrosis or for monitoring an efficacy of a pulmonary therapy.

[0005] Provided herein is an antisense oligonucleotide molecule modulating an expression or activity of a transposable element or a transcript transcribed from the transposable element, wherein the transposable element is selected from a group consisting of LTR16, LTR16A, LTR16A1, LTR16A2, LTR16B, LTR16B1, LTR16B2, LTR16C, LTR16D, LTR16D1, LTR16D2, LTR16E1, LTR16E2, ERV3-16A3 LTR, MER39, THE1A, THE1B, THE1C, THE1D, MSTA, MSTA1, MSTB, MSTB1, MSTB2, MSTC, MSTD, MLT1A0, MLT1A1,Attorney Docket No. 60448-717.601MLT1C, MLT1D, MLT1E, MLT1E1, MLT1E2, MLT1F, MLT1F1, MLT1F2, MLT1G1, MLT1G3, MLT1H, MLT1H1, MLT1I, MLT1J, MLT1J1, MLT1J2, MLT1K, MLT1L, MLT1M, MLT1N2, MLT1O, MLT2A1, MLT2A2, MLT2B1, MLT2B2, MLT2B3, MLT2B4, MLT2B5, MLT2C1, MLT2C2, MLT2D, MLT2E, MLT2F, MLT1A, MLT1B, MLT1E1A, MLT1E3, MLT1G, MLT1H2, MLT1C2, MLTIF-int, MST-int, MLT-int, MLT1H-int, MLT1J-int, THE1-int, HERV16, ERVL-E, HERVL, ERVL-B4, ERV3-16A3 I, LTR33, LTR50, LTR78, LTR41, LTR41B, HERV3-int, LTR13, HERVL18-int, MER66C, MER66D, or LTR19C subfamilies.

[0006] In some instances, the transposable element comprises a sequence that is at least 70%, at least 80%, at least 90%, or at least 95% identical to at least a fragment of a sequence selected from any one of SEQ ID NOs: 4-121. In some instances, the transposable element comprises a sequence that is at least 70%, at least 80%, at least 90%, or at least 95% identical to at least a fragment of a sequence selected from any one of SEQ ID NOs: 4, 10, 14, 15, 18, 27-32, and 34-38. In some instances, the transposable element comprises a sequence at least 70%, at least 80%, at least 90%, or at least 95% identical to at least a fragment of SEQ ID NO: 4. In some instances, the transposable element comprises a sequence of SEQ ID NO: 5, SEQ ID NO: 6, or wherein the transposable element or a fragment thereof is located in chr3: 45,818,736-45,818,762 (hg38) or chr3: 45,818,689-45,818,712 (hg38).

[0007] In some instances, the modulator induces or facilitates a change of a state of a cell from a first cellular state to a second cellular state. In some instances, the first cellular state or the second cellular state comprises an extracellular-cellular-matrix synthesizing state, a cytokinesecreting state, an inflammatory state, a cell dividing state, a cell pausing state.

[0008] In some instances, the transposable element transcript modulates a functional RNA. In some instances, the functional RNA comprises a messenger RNA (mRNA), a long noncoding RNA (IncRNA), a circular RNA, a small nuclear RNA (snRNAs), a small nucleolar RNA (snoRNAs), a microRNA, an X-inactive specific transcript (xist) RNA, or a combination thereof.

[0009] In some instances, the activity or expression level of transposable element or the transcript transcribed from the transposable element is associated with pulmonary fibrosis. In some instances, the expression level of the transcript transcribed from the transposable element is increased in a cell affected by pulmonary fibrosis compared to a healthy cell.

[0010] In some instances, the antisense oligonucleotide molecule comprises at least 9 consecutive nucleotides with no more than 3 mismatches from SEQ ID NOs: 124-456. In some instances, the antisense oligonucleotide molecule comprises a nucleic acid sequence at least 80%, at least 85%, at least 90%, at least 95%, identical to a sequence selected from SEQ ID NOs: 124-456.Attorney Docket No. 60448-717.601

[0011] In some instances, the antisense oligonucleotide molecule targets or binds to at least one of LTR16C integrant listed in Table 8.

[0012] In some instances, the antisense oligonucleotide molecule is a Gapmer with three consecutive LNAs in a 5 ’-wing region and two consecutive LNAs in a 3 ’-wing region. In some instances, one or more internucleotide linkage of antisense oligonucleotide molecule is substituted with a phosphorothioate backbone. In some instances, all internucleotide linkages of antisense oligonucleotide molecule are phosphorothioate internucleotide backbone.

[0013] Also provided herein is a pharmaceutical composition comprising the antisense oligonucleotide molecule of any one of the instances disclosed herein and a pharmaceutically acceptable salt, excipient, or derivative thereof.

[0014] Also provided herein is a kit comprising the antisense oligonucleotide molecule of any one of the instances provided herein or the pharmaceutical composition provided herein.

[0015] Also provided herein is a method of preventing, alleviating, or treating pulmonary fibrosis in a subject in need thereof, the method comprising administering to the subject an effective amount of the antisense oligonucleotide molecule of any one of instances provided herein or the pharmaceutical composition provided herein.

[0016] In some instances, the antisense oligonucleotide molecule of any one of the instances provided herein or the pharmaceutical composition provided herein reduces expression of a fibrosis-related marker in a fibroblast affected by the pulmonary fibrosis. In some instances, the fibrosis-related marker comprises smooth muscle α actin (ACTA2), alpha 1 chain of collagen type I (COL1A1), alpha 1 chain of collagen type 3 (COL3A1), fibroblast activation protein (FAP), fibronectin 1 (FN1), periostin (POSTN), collagen triple helix repeat containing 1 (CTHRC1), alpha 1 chain of collagen type 10 (COL10A1), matrix metalloproteinase 11 (MMP11), thrombospondin 2 (THBS2), latent transforming growth factor beta binding protein 2 (LTBP2), Integrin-α11 (ITGA11), or a combination thereof.

[0017] In some instances, the antisense oligonucleotide molecule of any one of the instances provided herein or the pharmaceutical composition provided herein restores an expression of a set of genes that are aberrantly expressed in idiopathic pulmonary fibrosis (IPF) comparable to a healthy cell. In some instances, the set of genes comprises one or more genes identified in Table 4.

[0018] Also provided herein is a method of reprogramming a myofibroblast into an early fibroblast precursor cell, a cell that is Top2a, Cenpa or ki67 positive, or a proliferating fibroblast, the method comprising contacting the myofibroblast with an effective amount of the antisense oligonucleotide molecule of any one of the instances provided herein or the pharmaceutical composition provided herein. In some instances, the early fibroblast precursor cell is aAttorney Docket No. 60448-717.601mesothelial cell, an early fibroblast cell, a mid fibroblast cell, or a mesenchymal cell. In some instances, the cell that is Top2a, Cenpa or ki67 positive is a mesenchymal progenitor cell, and optionally wherein the mesenchymal progenitor cell is an epithelial progenitor cell, an endothelial progenitor cell, or a fibroblast progenitor cell.

[0019] Also provided herein is a method of slowing or reversing aging of a pulmonary tissue in a subject, the method comprising administering to the subject an effective amount of the antisense oligonucleotide molecule of any one of the instances provided herein or the pharmaceutical composition of provided herein.

[0020] In some instances, an upregulated proteostasis is observed in the pulmonary tissue, and optionally wherein an expression of Zmpste24 or Lamp2 is increased in the pulmonary tissue. In some instances, an upregulated macro-autophagy is observed in the pulmonary tissue, and optionally wherein the expression of Atg5 or Atg7 is increased in the pulmonary tissue. In some instances, a more active telomerase is observed in the pulmonary tissue, and optionally wherein an expression of Tert or Terc is increased in the pulmonary tissue. In some instances, an age-related inflammation or an age-related tissue repair capability is improved in the pulmonary tissue. In some instances, more M0 macrophages or fewer profibrotic M2 macrophages are observed in the pulmonary tissue. In some instances, fewer white blood cells or fewer macrophages are observed in a bronchioalveolar lavage of the subject. In some instances, a number of total T cells or activated T cells is decreased in the pulmonary tissue, or a number of immunosuppressive Ctla4-expressing cells is increased in the pulmonary tissue. In some instances, a cell-cell communication between a fibroblast and an immune cell (e.g., a T cell, an M0, Ml, or M2 macrophage) is decreased in the pulmonary tissue. In some instances, the antisense oligonucleotide molecule is delivered by inhalation.INCORPORATION BY REFERENCE

[0021] All publications, patents, and patent applications mentioned in this specification are herein incorporated by reference to the same extent as if each individual publication, patent, or patent application was specifically and individually indicated to be incorporated by reference. To the extent publications and patents or patent applications incorporated by reference contradict the disclosure contained in the specification, the specification is intended to supersede and / or take precedence over any such contradictory material.Attorney Docket No. 60448-717.601BRIEF DESCRIPTION OF THE DRAWINGS

[0022] The application contains at least one drawing executed in color. Copies of this patent or patent application publication with color drawing(s) will be provided by the Office upon request and payment of the necessary fee.

[0023] The novel features of the disclosure are set forth with particularity in the appended claims. A better understanding of the features and advantages of the present disclosure will be obtained by reference to the following detailed description that sets forth illustrative instances, in which the principles of the disclosure are utilized, and the accompanying drawings (also “Figure” and “FIG.” herein), of which:

[0024] FIGs. 1A-1G illustrate qPCR results measuring various fibrotic markers in HLF MyoFB upon treatment with ASOs. FIG. 1A shows qPCR results for FN1 in HLF MyoFB upon treatment with ASOs. FIG. IB shows qPCR results for ACTA2 in HLF MyoFB upon treatment with ASOs. FIG. 1C shows qPCR results for FAP in HLF MyoFB upon treatment with ASOs.FIG. ID shows qPCR results for COL1A1 in HLF MyoFB upon treatment with ASOs. FIG. IE shows qPCR results for COL3A1 in HLF MyoFB upon treatment with ASOs. FIG. IF shows qPCR results for POSTN in HLF MyoFB upon treatment with ASOs. FIG. 1G shows qPCR results for CTHRC1 in HLF MyoFB upon treatment with ASOs.

[0025] FIG. 2 shows mean body weight of mice treated with vehicle, scramble control, ASO-1, or ASO-3 over 14 days.

[0026] FIGs. 3A-3C illustrate measurement of alanine transaminase (ALT), aspartate transaminase (AST) and creatinine in the plasma of mice treated with vehicle, scramble control, ASO-1, or ASO-3 over 14 days. FIG. 3A shows measurement of ALT in mice treated with vehicle, scramble control, ASO-1, or ASO-3 over 14 days. FIG. 3B shows measurement of AST in mice treated with vehicle, scramble control, ASO-1, or ASO-3 over 14 days. FIG. 3C shows measurement of creatinine in mice treated with vehicle, scramble control, ASO-1, or ASO-3 over 14 days.

[0027] FIGs. 4A-4G illustrate analysis of snRNA-seq data derived from snap-frozen biopsies collected from the lungs of mice treated with ASO-3 at different time points (day 3, day 5, day 7, day 14). FIG. 4A shows cell annotation of the snRNA-seq data. FIG. 4B shows expression of Top2a and Mki67 in different cell types. FIG. 4C shows quantification of alveolar fibroblasts, precursor fibroblasts, and proliferative fibroblasts at different time points post treatment of ASO-3. FIG. 4D shows analysis of cell cycle state of fibroblast subtypes. FIG. 4E shows expression of Top2a and Mki67 in different fibroblast subtypes. FIG. 4F shows expression of precursor fibroblast signature in different fibroblast subtypes. FIG. 4G shows quantification of AT2 cells, endothelial cells, fibroblasts, and immune cells at different time points post treatment of ASO-3.Attorney Docket No. 60448-717.601

[0028] FIGs. 5A-5K illustrate upregulation of regulons or gene signatures upon targeting integrants with ASOs (TRUE) versus not (FALSE). FIG. 5A shows upregulation of the FOSL2 regulon upon targeting integrants with ASOs. FIG. 5B shows upregulation of the NFIA regulon upon targeting integrants with ASOs. FIG. 5C shows upregulation of the NR3C1 regulon upon targeting integrants with ASOs. FIG. 5D shows upregulation of the TCF4 regulon upon targeting integrants with ASOs. FIG. 5E shows upregulation of the FOSL1 regulon upon targeting integrants with ASOs. FIG. 5F shows upregulation of the KLF7 regulon upon targeting integrants with ASOs. FIG. 5G shows upregulation ofthe FOXP1 regulon upon targeting integrants with ASOs. FIG. 5H shows upregulation of the NPAS2 regulon upon targeting integrants with ASOs.FIG. 5I shows upregulation of the BHLHE40 regulon upon targeting integrants with ASOs. FIG.5J shows upregulation of the PPARG regulon upon targeting integrants with ASOs. FIG. 5K shows upregulation of the CREB3L2 regulon upon targeting integrants with ASOs.

[0029] FIGs. 6A-6K illustrate downregulation of regulons or gene signatures upon targeting integrants with ASOs (TRUE) versus not (FALSE). FIG. 6A shows downregulation of the RUNX1 regulon upon targeting integrants with ASOs. FIG. 6B shows downregulation of senescence gene signature upon targeting integrants with ASOs. FIG. 6C shows downregulation of IPF / HLF gene signature upon targeting integrants with ASOs. FIG. 6D shows downregulation of the MAFF regulon upon targeting integrants with ASOs. FIG. 6E shows downregulation of old gene signature upon targeting integrants with ASOs. FIG. 6F shows downregulation of the SMAD3 regulon upon targeting integrants with ASOs. FIG. 6G shows downregulation of genes encoding proteomic biomarkers for poor IPF prognosis upon targeting integrants with ASOs. FIG. 6H shows downregulation of the NFIC regulon upon targeting integrants with ASOs. FIG.61 shows downregulation of the FOSB regulon upon targeting integrants with ASOs. FIG. 6J shows downregulation of ASO- 1 target engagement panel (TEP) upon targeting integrants with ASOs. FIG. 6K shows downregulation of ASO-3 target engagement panel (TEP) upon targeting integrants with ASOs.

[0030] FIG. 7 shows ChromHMM analysis of the top 20 differentially expressed LTR subfamilies in primary human fibroblasts.

[0031] FIG. 8 shows EBF1 and SPI1 motifs in enhancer regions of various transposable elements.

[0032] FIGs 9A-9C illustrate expression of ASO- 1 target engagement panel (TEP) and ASO-3 TEP in in-vivo human lung biopsies. FIG. 9A shows different cell types within human lung biopsies. FIG. 9B shows upregulation of ASO-1 TEP genes in disease relevant fibroblasts sub-types (e.g., myofibroblasts, activated fibrotic fibroblasts). FIG. 9C shows upregulation ofAttorney Docket No. 60448-717.601ASO-3 TEP genes in disease relevant fibroblasts sub-types (e.g., myofibroblasts, activated fibrotic fibroblasts).

[0033] FIG. 10 shows measurement of fibroblast-adapted epigenetic aging clock in ASO-treated human lung fibroblasts.

[0034] FIGs. 11A-11B illustrate analysis of fibrosis in lungs of mice treated with vehicle, and bleomycin mouse model treated with scramble control, ASO-1 or ASO-3. FIG. 11A shows fibrosis area in lungs of mice treated with vehicle, and bleomycin mouse model treated with vehicle, scramble control, ASO-1 or ASO-3. FIG. 11B shows fibrosis severity in lungs of mice treated with vehicle, and bleomycin mouse model treated with non-targeting control, ASO-1 or ASO-3.

[0035] FIGs. 12A-12B illustrate total white blood cells and macrophage numbers in bronchioalveolar lavage (BAL) of mice treated with vehicle, and bleomycin mouse model treated with scramble control, ASO-1 or ASO-3. FIG. 12A shows total white blood cells bronchioalveolar lavage (BAL) counts of mice treated with vehicle, and bleomycin mouse model treated with scramble control, ASO-1 or ASO-3. FIG. 12B shows macrophage numbers in bronchioalveolar lavage (BAL) of mice treated with vehicle, and bleomycin mouse model treated with scramble control, ASO-1 or ASO-3.

[0036] FIG. 13 shows representative picrosirius red (PSR) staining images of lungs from bleomycin mice treated with ASO1 or ASO3, and lungs from mice treated with non-targeting control or vehicle.

[0037] FIG. 14 shows expression of encoding circulating biomarkers associated with negative IPF prognosis mice treated with vehicle, and bleomycin mouse model treated with nontargeting control, ASO-1 or ASO-3.DETAILED DESCRIPTION

[0038] The present disclosure includes that certain transposable elements (TEs) are associated with cell-state transition, and such TEs are key elements in regulating various elements in signaling pathways of cell-state transitions. As such, the present disclosure further includes that by modulating a transposable element (TE) associated with cell-state transition, the cell state of a diseased cell can be reverted to a cell state similar to a healthy counterpart.

[0039] Certain TEs play a role as gene regulatory elements, i.e., regulatory element for transcription. In some instances, certain TEs can regulate gene expression that are cell-, stage-, development-specific of an organism. Consistently, its expression and / or activity can be cell-, stage-, specific-, development-specific of an organism. The nature of TEs, having multiple copies of the same, also provides a golden opportunity for concerted regulation of the functional groupAttorney Docket No. 60448-717.601by synchronizing all relevant transcriptional networks under the control of the transposable elements of the same subfamily.

[0040] However, one of the biggest challenges lies in the sheer volume of TEs, which takes up about 50% of the Human Genome. For example, using traditional methods, it is hardly possible to narrow down the TEs that exhibit precise, specific, and potent functions as cell-state reprogramming in fibrosis associated disease-driving cell states. In some instances, the classification and identification of the transposable element is based on Dfam, a source of consensus models and sequences. In some instances, the classification and identification of the transposable element is based on Repbase, a source of consensus models and sequences of transposable elements and other repeats. In some instances, the classification and identification of the transposable element is based on Repeatmasker, which includes a program that analyzes consensus models from outsides sources (e.g., Dfam or Repbase) and runs them on genomes for annotation, with a list of loci with coordinates as an output. In some instances, transposable elements are identified or annotated by performing nhmmscan from the HMMER suite (e.g., http: / / hmmer.org / and Eddy et al., PLoS Comput Biol. 2011) on a target genome.

[0041] Described herein are modulators of a transposable element, wherein the modulators induce or facilitate a change of a state of a cell from a first cellular state to a second cellular state. Further described herein is a modulator comprising an inhibitory oligonucleotide (e.g., an antisense oligonucleotide (ASO)). In some instances, the ASO comprises at least 9 consecutive nucleotides with no more than 3 mismatches from 5’ - CGGAGGCATGAGGTAG -3’ (SEQ ID NO: 1). Further described herein is a modulator comprising an antisense oligonucleotide (ASO), wherein the ASO comprises at least 9 consecutive nucleotides with no more than 3 mismatches from 5’- TGAGCAGGTTAGCACT -3’ (SEQ ID NO: 2). Further described herein in details is a modulator comprising an antisense oligonucleotide (ASO), wherein the ASO comprises at least 9 consecutive nucleotides with no more than 3 mismatches from 5’- CTACCTCATGCCTCCG -3’ (SEQ ID NO: 3). Further described herein in details is a modulator comprising an antisense oligonucleotide (ASO), wherein the ASO comprises at least 9 consecutive nucleotides with no more than 3 mismatches from SEQ ID NOs: 124-456. Further described herein are synthetic polynucleic acids comprising a nucleic acid sequence of a transposable element or a portion thereof, wherein the synthetic polynucleic acids induce or facilitate a change of a state of a cell from a first cellular state to a second cellular state. Further described herein are pharmaceutical compositions comprising the modulator described herein or the synthetic polynucleic acid described herein, and a pharmaceutically acceptable salt or derivative thereof. Further described herein are kits comprising the modulator described herein or the synthetic polynucleic acid described herein, or the pharmaceutical composition described herein. Further described hereinAttorney Docket No. 60448-717.601are methods of preventing, alleviating, or treating pulmonary fibrosis in a subject in need thereof. Further described herein are methods of reprogramming a myofibroblast into a new cell type. Further described herein are methods of slowing or reversing aging of a pulmonary tissue in a subject. Further described herein are methods for diagnosing or monitoring pulmonary fibrosis in a subject. Further described herein are methods of predicting severity and progression of pulmonary fibrosis in a subject. Further described herein are methods of monitoring an efficacy of a pulmonary therapy in a subject. Further described herein are methods of evaluating or monitoring pulmonary tissue regeneration in a subject. Further described herein are methods of evaluating or monitoring efficacy of a treatment to induce pulmonary reprogramming.Regulatory Transposable Elements

[0042] Presence of certain TEs in the mammalian (e.g., human) genome are the results of ancient viral infections where a portion of the virus genome was integrated into the host (mammalian, human) genome. In some instances, the transposable element described herein is a class I transposable element, which comprises transposable elements that transpose through RNA intermediates. In some instances, the transposable element described herein is a class II transposable element, which comprises transposable elements that do not use RNA as a transposition intermediate.

[0043] There is a plurality of superfamilies of TEs (e.g., LINE and LTR), each of which comprises a plurality of families. For example, the superfamily of LINE comprises LI (LINE-1) family, L2 (LINE-2) family, etc. LTR superfamily comprises LTR / ERV1, LTR-ERVL, LTR / ERVK families, etc. Each family further comprises a plurality of subfamilies. For example, LI Hs and LlMd5 are two exemplary subfamilies of the family of LI (LINE-1). L2c is an exemplary subfamily of the family of L2 (LINE-2). HERVH-int and LTR 12 are two exemplary subfamilies of the family of LTR / ERV1. LTR16C is an exemplary subfamily of the family of LTR / ERVL. LTR5_Hs is an exemplary subfamily of the family of LTR / ERVK. See Carey et al., Mobile DNA volume 12, Article number: 4 (2021). In some instances, the leading candidates of transposable elements described herein are examined on the level of subfamily.

[0044] Expression of the certain transposable elements described herein may be tissue specific. In some instances, the transposable elements described herein are highly, exclusively, or distinctly expressed in one or more tissues or sub-tissues in the musculoskeletal system. In some instances, the transposable elements described herein are highly, exclusively, or distinctly expressed in one or more tissues in the digestive system (e.g., stomach, intestine, liver, pancreas, etc.) or one or more sub-tissues thereof. In some instances, the transposable elements described herein are highly, exclusively, or distinctly expressed in one or more tissues in the respiratory system (e.g., lungs) or one or more sub-tissues thereof. In some instances, the transposableAttorney Docket No. 60448-717.601elements described herein are highly, exclusively, or distinctly expressed in one or more tissues in the urinary system (e.g., kidney, bladder, etc.) or one or more sub-tissues thereof. In some instances, the transposable elements described herein are highly, exclusively, or distinctly expressed in one or more tissues in the reproductive system (e.g., ovaries, testes, etc.) or one or more sub-tissues thereof. In some instances, the transposable elements described herein are highly, exclusively, or distinctly expressed in one or more tissues in the endocrine system (e.g., pituitary gland, thyroid gland, etc.) or one or more sub-tissues thereof. In some instances, the transposable elements described herein are highly, exclusively, or distinctly expressed in one or more tissues in the circulatory system (e.g., hearts, arteries, veins, etc.) or one or more sub-tissues thereof. In some instances, the transposable elements described herein are highly, exclusively, or distinctly expressed in one or more tissues in the lymphatic system (e.g., lymph nodes, thymus, spleens, etc.) or one or more sub-tissues thereof. In some instances, the transposable elements described herein are highly, exclusively, or distinctly expressed in one or more tissues in the nervous system (e.g., brains, spinal cords, etc.) or one or more sub-tissues thereof. In some instances, the transposable elements described herein are highly, exclusively, or distinctly expressed in one or more tissues in the dermal system (e.g., skin, epithelium, etc.) or one or more sub-tissues thereof. As used herein, sub-tissues include one or more specific cell types of the tissue, or a fraction of the tissue. In some instances, sub-tissues may be distinguished from the rest of the tissue by its location, cell types, or functions.

[0045] In some instances, the transposable element modulates the regulatory networks associated with cell-state maintenance. In other instances, the transposable element modulates the regulatory networks associated with cell-state transition. In other instances, the transposable element induces a phenotypical change of a cell. In other instances, the transposable element modulates the regulatory networks associated with onset, development / progress, or prognosis of a fibrosis or symptoms thereof.

[0046] Accordingly, in some instances, a modulator modulating expression or function of the transposable element induces or facilitates a change of a state of a cell from a first cellular state to a second cellular state. In some instances, the modulator induces or facilitates a change of a state of a cell from a pathological cell state to a non-pathological cell state. In some instances, the pathological cell state is driven by environmental signals. In some instances, environmental signals include physiological stress, starvation, inflammatory cytokine signaling, differentiation signals, dedifferentiation signals, paracrine signaling, mechanical stress, or other signals thereof.

[0047] In some instances, the first cellular state or the second cellular state comprises an extracellular-cellular-matrix synthesizing state, a cytokine-secreting state, an inflammatory state, a cell dividing state, or a cell pausing state. In some instances, the first cellular state is theAttorney Docket No. 60448-717.601extracellular-cellular-matrix synthesizing state. In some instances, the second cellular state is the inflammatory state. Accordingly, in some instances, the modulators induce or facilitate a change of a state of a cell from the extracellular-cellular-matrix synthesizing state to the inflammatory state. In some instances, the modulators induce or facilitate a change of a state of a cell from the extracellular-cellular-matrix synthesizing state to the extracellular-cellular-matrix nonsynthesizing state. In some instances, the modulators induce or facilitate a change of a state of a cell from the non-inflammatory state to the inflammatory state. In some instances, the modulators induce or facilitate a change of a state of a cell from the cell pausing state to the dividing cell state.

[0048] In some instances, the first cellular state is a state that phenocopies a state of a fibroblast, an interstitial fibroblast, a resident fibroblast, a proliferative fibroblast, a proliferative myofibroblast, a precursor fibroblast, a EBF1+ fibroblast, a chondrocyte, a myofibroblast, a lipofibroblast, an alveolar fibroblast, a contractile myofibroblast, a quiescent myofibroblast, a pulmonary fibroblast progenitor, a cardiopulmonary fibroblast progenitor, a regeneration-competent fibroblast, an adventitial fibroblast, a peribronchial fibroblast, an airway fibroblast, an alveolar fibroblast, an early fibroblast, an early mesothelial cell, an intermediate fibroblast, a late mesothelial cell, a mesenchymal progenitor, a mesenchymal cell, a mid airway smooth muscle cell, a late airway smooth muscle cell, a mid airway fibroblast, a blasaloid cell (e.g., an aberrant basaloid cell), or a pericyte. In some instances, the second cellular state is a state that phenocopies a state of a fibroblast, an interstitial fibroblast, a resident fibroblast, a proliferative fibroblast, a proliferative myofibroblast, a precursor fibroblast, a EBF1+ fibroblast, a chondrocyte, a myofibroblast, a lipofibroblast, an alveolar fibroblast, a contractile myofibroblast, a quiescent myofibroblast, a pulmonary fibroblast progenitor, a cardiopulmonary fibroblast progenitor, a regeneration-competent fibroblast, an adventitial fibroblast, a peribronchial fibroblast, an airway fibroblast, an alveolar fibroblast, an early fibroblast, an early mesothelial cell, an intermediate fibroblast, a late mesothelial cell, a mesenchymal progenitor, a mesenchymal cell, a mid airway smooth muscle cell, a late airway smooth muscle cell, a mid airway fibroblast, a blasaloid cell (e.g., an aberrant basaloid cell), or a pericyte.

[0049] To maintain a cell state, to induce a cell-state transition, to induce a phenotypical change of a cell, to interfere with the onset of a fibrosis or symptoms thereof, to control the development / progress of a fibrosis or symptoms thereof, or to serve as a prognosis of a fibrosis or symptoms thereof, in some instances, the transposable element is differentially expressed in one cell state described herein. In some instances, the transposable element is differentially expressed in a fibrotic cell. In some instances, the transposable element is differentially expressed along with a differential expression of a marker gene associated with fibrosis.Attorney Docket No. 60448-717.601

[0050] To maintain a cell state, to induce a cell-state transition, to induce a phenotypical change of a cell, to interfere with the onset of a fibrosis or symptoms thereof, to control the development / progress of a fibrosis or symptoms thereof, or to serve as a prognosis of a fibrosis or symptoms thereof, in some instances, the transposable element modulates a functional RNA. In some instances, the functional RNA comprises a messenger RNA (mRNA), a long noncoding RNA (IncRNA), a circular RNA, a small nuclear RNAs (snRNAs), a small nucleolar RNAs (snoRNAs), a microRNA, an X-inactive specific transcript (xist) RNA, or a combination thereof. In some instances, the functional RNA comprises the IncRNA. Accordingly, in some instances, the transposable element modulates a IncRNA.

[0051] In some instances, the transposable element modulates expression or activity of a IncRNA. In some instances, the transposable element is transcribed from the same strand of the genome with the strand transcribing IncRNA modulated by the transposable element. In some instances, the transposable element is transcribed from a different strand (e.g., opposite strand) of the genome from the strand transcribing the IncRNA modulated by the transposable element.

[0052] To maintain a cell state, to induce a cell-state transition, to induce a phenotypical change of a cell, to interfere with the onset of a fibrosis or symptoms thereof, to control the development / progress of a fibrosis or symptoms thereof, or to serve as a prognosis of a fibrosis or symptoms thereof, in some instances, the transposable element is associated with certain enhancers and / or transcription factors. In some instances, the transposable element comprises an epigenetic modification or an epitranscriptomic modification. In some instances, the epigenetic modification comprises H3K27Ac, H3K4me3, H3K4me1, H4K16ac, H3K27me3, H3K79me2, H3K36me3, H2AFZ, H3K9ac, H3K4me2, H4K20mel, H2BK120ac, H3K56ac, H2AK9ac, H3K18ac, H4K5ac, H2AK5ac, H3K9mel, H3K4ac, H2BK5ac, H3K14ac, H3K79mel, H3K23ac, H2BK15ac, H3K4me2, H2BK12ac, H4K91ac, H4K20mel, H2BK20ac, H4K8ac, or a combination thereof. In some instances, an enhancer-binding transcriptional activator (e.g., bromodomain-containing protein 4 (BRD4)) binds to the epigenetic modification. In some instances, the epitranscriptomic modification comprises N6-methyladenine (m6A), Nl-methyladenosine (ml A), inosine (I), pseudouridine ( ). 5 -methylcytosine (m5C), methylguanosine (mlG), N6, N6-dimethyladenosine (m62A), 4-thiouridine (s4U), ora combination thereof. In some instances, the DNA sequence (e.g., genomic sequence) of the transposable element is bound by or bears a binding motif being bound by a transcription factor that is associated with cell-state maintenance, transition, phenotypical changes, onset, development / progress, or prognosis of a fibrosis or symptoms thereof.

[0053] To maintain a cell state, to induce a cell-state transition, to induce a phenotypical change of a cell, to interfere with the onset of a fibrosis or symptoms thereof, to control theAttorney Docket No. 60448-717.601development / progress of a fibrosis or symptoms thereof, or to serve as a prognosis of a fibrosis or symptoms thereof, in some instances, the transposable element directly binds to a target DNA, RNA, or protein to modulate the expression or activity of the target DNA, RNA, or protein. In other instances, the transposable element indirectly binds to a target DNA, RNA, or protein to modulate the expression or activity of the target DNA, RNA, or protein.

[0054] In some instances, the DNA copies of the transposable element described herein are identified by Nanopore direct RNA sequencing. In some instances, the DNA copies of the transposable element described herein are identified by total RNA-Seq. In some instances, the DNA copies of the transposable element described herein are identified by polyA-selected RNA-seq. In some instances, the DNA copies of the transposable element described herein are identified by GWAS and common variant calling. In some instances, the DNA copies of the transposable element described herein are identified by CUT and RUN probing, for example, histone modifications or transcription factors. In some instances, the DNA copies of the transposable element described herein are identified by ChlP-Seq probing, for example, histone modifications or transcription factors. In some instances, the DNA copies of the transposable element described herein are identified by Pro-Seq, Pro-Cap, GRO-seq, or combination thereof, examining nascent transcription as a proxy for enhancer association. In some instances, the DNA copies of the transposable element described herein are identified by MicroC examining enhancer promoter contacts in 3D for gene regulation network. In some instances, the DNA copies of the transposable element described herein are identified by snATAC-Seq. In some instances, the DNA copies of the transposable element described herein are identified by bulk ATAC-seq. In some instances, the DNA copies of the transposable element described herein are identified by DNase-Seq.

[0055] In some instances, the transposable element described herein is a genetic component regulating any functional RNAs associated with an onset, development, or progress of a type of fibrosis (e.g., pulmonary fibrosis) as a master regulator. In some instances, the expression mapping of the transposable element described herein is assessed by total RNA-Seq. In some instances, the expression mapping of the transposable element described herein is assessed by Pro-Seq. In some instances, the expression mapping of the transposable element described herein is assessed by single-cell RNA (scRNA)-Seq. In some instances, the expression mapping of the transposable element described herein is assessed by single nuclear RNA (snRNA)-Seq.

[0056] In some instances, the RNA modifications and edits of the transposable element described herein is assessed by Nanopore direct RNA sequencing. In some instances, the RNA modifications and edits of the transposable element described herein is assessed by total RNA-Seq. In some instances, the RNA structure features of the transposable element described hereinAttorney Docket No. 60448-717.601are assessed by Nanopore direct RNA sequencing. In some instances, the RNA structure features of the transposable element described herein are assessed by total RNA-Seq. In some instances, the RNA structure features of the transposable element described herein are assessed by polyA RNA-Seq. In some instances, the RNA structure features of the transposable element described herein are assessed by in silico predictive structural models. In some instances, the RNA structure features of the transposable element described herein are assessed by any suitable immunoprecipitation techniques. Non-limiting immunoprecipitation techniques include individual protein immunoprecipitation (IP), protein complex immunoprecipitation (co-IP), chromatin immunoprecipitation (ChIP), ribonucleoprotein (RNP) immunoprecipitation, tagged protein IP, or derivatives thereof.

[0057] In some instances, DNA modifications (e.g., DNA methylation, CpG methylation, CHG DNA methylation, CHH DNA methylation, hydroxymethylation) of the transposable element described herein are assessed by Nanopore sequencing. In some instances, DNA modifications (e.g., DNA methylation, CpG methylation, hydroxymethylation) of the transposable element described herein are assessed by Reduced representation bisulfite sequencing (RRBS). In some instances, DNA modifications (e.g., DNA methylation, CpG methylation, hydroxymethylation) of the transposable element described herein are assessed by Whole genome bisulfite sequencing (WGBS). In some instances, DNA modifications (e.g., DNA methylation, CpG methylation, hydroxymethylation) of the transposable element described herein are assessed by Methylated DNA immunoprecipitation (MeDIP). In some instances, DNA modifications (e.g., DNA methylation, CpG methylation, hydroxymethylation) of the transposable element described herein are assessed by hydroxyMeDIP. In some instances, DNA modifications (e.g., DNA methylation, CpG methylation, hydroxymethylation) of the transposable element described herein is assessed by Illumina methylation arrays. In some instances, DNA modifications (e.g., DNA methylation, CpG methylation, hydroxymethylation) of the transposable element described herein are assessed by duet evoC kit or any other suitable methods of capturing DNA methylation.

[0058] In some instances, the binding of the transposable element described herein to one or more transcription factors and / or enhancers is assessed by CUT and RUN probing, for example, histone modifications or transcription factors. In some instances, the binding of the transposable element described herein to one or more transcription factors and / or enhancers is assessed by ChlP-Seq probing, for example, histone modifications or transcription factors. In some instances, the binding of the transposable element described herein to one or more transcription factors and / or enhancers is assessed by Pro-Seq, Pro-Cap, GRO-seq, or combination thereof, examining nascent transcription as a proxy for enhancer association. In some instances, the binding of theAttorney Docket No. 60448-717.601transposable element described herein to one or more transcription factors and / or enhancers is assessed by MicroC examining enhancer promoter contacts in 3D for gene regulation network. In some instances, the binding of the transposable element described herein to one or more transcription factors and / or enhancers is assessed by snATAC-Seq. In some instances, the binding of the transposable element described herein to one or more RNA-binding proteins is assessed by enhanced crosslinking and immunoprecipitation followed by high-throughput sequencing (eCLIP), irCLIP, iCLIP, spyCLIP, HITS-CLIP, TLC-CLIP, or other variations thereof. See e.g., Van Nostrand et al., Nature Methods volume 13, pp. 508-514 (2016).

[0059] In some instances, the binding of the transposable element described herein to one or more RNA-binding protein is assessed by dataset mining focusing on RNA-binding protein such as T-cell intracellular antigen 1 related protein (TIAR).

[0060] In some instances, the enrichment of the transposable element described herein in one or more IncRNAs is assessed by investigating IncRNA catalogues developed from one or more databases. In some instances, the enrichment of the transposable element described herein in one or more IncRNAs is assessed by polyA RNASeq. In some instances, the enrichment of the transposable element described herein in one or more IncRNAs is assessed by total RNA-Seq. In some instances, the enrichment of the transposable element described herein in one or more IncRNAs is assessed by scRNA-Seq. In some instances, the enrichment of the transposable element described herein in one or more IncRNAs is assessed by snRNA-Seq.Regulatory Transposable Elements associated with Fibrosis

[0061] Provided herein are transposable elements identified by the methodologies described herein that exhibit one or more features that are associated with fibrosis (e.g., DNA copies specifically expressed in fibrosis, RNA expression specifically associated with fibrosis, interaction with transcription factors and / or enhancers that are specifically associated with fibrosis, interaction with RNA-binding proteins that are specifically associated with fibrosis).

[0062] Idiopathic pulmonary fibrosis (IPF) is marked by uncontrolled proliferation and survival of activated fibroblasts, known as myofibroblasts, causing excessive extracellular matrix deposition, leading to lung fibrosis and damage to alveoli and bronchioles. Therefore, in some instances, targeting the lung fibrosis driving cell state, i.e. myofibroblasts, can significantly reduce IPF burden and promote lung rejuvenation.

[0063] In some instances, the transposable element is differentially expressed in a cell where a fibrosis is induced. In some instances, the transposable element is differentially expressed in a cell where a fibrosis progresses. In some instances, the transposable element is differentially expressed in a tissue where a fibrosis is induced. In some instances, the transposable element is differentially expressed in a tissue where a fibrosis progresses. In some instances, the differentialAttorney Docket No. 60448-717.601expression of the transposable element is associated with the differential expression of a RNA, a protein or an element of a signaling pathway related to the initiation, development, progress, or prognosis of a fibrosis. In some instances, the transposable element regulates the differential expression of a RNA, a protein or an element of a signaling pathway related to the initiation, development, progress, or prognosis of a fibrosis. Therefore, in some instances, modulating the transposable element induces a cell-state transition in a cell affected by fibrosis. In some instances, modulating the transposable element induces a cell-state transition in a cell expected to be affected by fibrosis. In some instances, modulating the transposable element prevents the initiation and / or progression of fibrosis or its symptoms thereof. In some instances, modulating the transposable element reverses the progression of fibrosis. In some instances, modulating the transposable element alleviates or cure the symptoms of the fibrosis.

[0064] In some instances, the transposable element is associated with progressive pulmonary fibrosis (PPF), interstitial lung disease (ILD), pulmonary hypertension-associated interstitial lung disease (PH-ILD), scleroderma-associated interstitial lung disease (SSc-ILD), rheumatoid arthritis-associated interstitial lung disease (RA-ILD), or Sjogren's syndrome-associated interstitial lung disease. In some instances, the transposable element is associated with pulmonary fibrosis. In some instances, the pulmonary fibrosis is idiopathic pulmonary fibrosis. In some instances, an RNA expression level of the transposable element is altered in a cell affected by pulmonary fibrosis compared to a healthy cell. In some instances, the RNA expression level of the transposable element is increased in a cell affected by pulmonary fibrosis compared to a healthy cell. In some instances, the RNA expression level of the transposable element is at least 10%, 20%, 30%, 40%, 50%, 60%, 70, 80%, or 90% more than in a cell affected by pulmonary fibrosis compared to a healthy cell. In some instances, the RNA expression level of the transposable element is at least 1.5 folds, 2 folds, 3 folds, 4 folds, 5 folds, 6 folds, 7 folds, 8 folds, 9 folds, or 10 folds higher in a cell affected by pulmonary fibrosis compared to a healthy cell. In some instances, the RNA expression level of the transposable element is decreased in a cell affected by pulmonary fibrosis compared to a healthy cell. In some instances, the RNA expression level of the transposable element is at least 10%, 20%, 30%, 40%, 50%, 60%, 70, 80%, or 90% lower than in a cell affected by pulmonary fibrosis compared to a healthy cell.

[0065] In some instances, the transposable element is associated with differential expression of a marker gene of pulmonary fibrosis. In some instances, the marker genes of pulmonary fibrosis include smooth muscle α actin (ACTA2), alpha 1 chain of collagen type I (COL1A1), alpha 1 chain of collagen type 3 (COL3A1), fibroblast activation protein (FAP), fibronectin 1 (FN1), periostin (POSTN), collagen triple helix repeat containing 1 (CTHRC1), alpha 1 chain of collagen type 10 (COL10A1), matrix metalloproteinase 11 (MMP11), thrombospondin 2Attorney Docket No. 60448-717.601(THBS2), latent transforming growth factor beta binding protein 2 (LTBP2), Integrin-α11 (ITGA11), or a combination thereof.

[0066] In some instances, the DNA sequence (e.g., genomic DNA sequence) of the transposable element is bound by or bears a binding motif being bound by a pulmonary-fibrosis-related transcription factor. In some instances, the DNA sequence (e.g., genomic DNA sequence) of the transposable element contains a domain or a binding motif that binds to a pulmonary-fibrosis-related transcription factor. In some instances, the binding motif is a common motif or any consensus motif. In some instances, the pulmonary-fibrosis-related transcription factor comprises friend leukemia integration 1 transcription factor (FLU), interferon regulatory factor 3 (IRF3), interferon regulatory factor 4(IRF4), (ETS like-1 protein (ELK1), activator protein 1 (AP-1), C-terminal binding protein 2 (CTBP2), Spi-1 Proto-Oncogene (SPI1 / PU.1), transcription factor 7 (TCF7), transcription factor 7-like 1 (TCF7L1), transcription factor 7-like 2 (TCF7L2), transcription Factor 21 (TCF21), CCAAT enhancer binding protein beta (CEBPB), forkhead box protein Al (FOXA1), forkhead box protein A2 (FOXA2), forkhead box protein 04 (FOXO4), forkhead box protein LI (FOXL1), forkhead box protein L2 (FOXL2), forkhead Box Ml(FOXMl), T-box transcription factor 4 (TBX4), T-box transcription factor 5 (TBX5), oddskipped related 1 (OSR1), early B-cell factor 1 (EBF1), early B-cell factor 2 (EBF2), early B-cell factor 3 (EBF3), twist-related protein 1 (TWIST1), SMAD family member 2 (SMAD2), SMAD family member 3 (SMAD3), nuclear factor-1 (NFl), NK6 homeobox 1 (NKX6-1), NK2 homeobox 1 (NKX2.1), RUNX family transcription factor 2 (RUNX2), RUNX family transcription factor 3 (RUNX3), POU class 2 homeobox associating factor 1 (POU2AF1), high mobility group AT-hook 2 (HMGA2), lymphoid enhancer-binding factor 1 (LEF1), paired related homeobox 1 (PRRX1), tumor protein p63 (TP63), forkhead box protein Pl (FOXP1), Meis homeobox 1 (MEIS1), TGFB induced factor homeobox 1 (TGIF1), paired related homeobox 2 (PRRX2), TEA domain family member 1 (TEAD1), TEA domain family member 2 (TEAD2), TEA domain family member 3 (TEAD3), TEA domain family member 4 (TEAD4), signal transducer and activator of transcription 1 (STAT1), signal transducer and activator of transcription 3 (STAT3), signal transducer and activator of transcription 6 (STAT6), nuclear factor-kappa B 1 (NFKBl), nuclear factor-kappa B2 (NFKB2), AT-rich interactive domaincontaining protein 3 A (ARID3A), forkhead box protein SI (FOXS1), forkhead box protein J2 (FOXJ2), forkhead box protein II (FOXI1), forkhead box protein Fl (FOXF1), forkhead box protein El (FOXE1), forkhead box protein A3 (FOXA3), forkhead box protein D3 (FOXD3), MYC-Associated Zinc Finger Protein (MAZ), Zinc Finger Protein X-Linked (ZFX), Zinc Finger Protein Y-Linked (ZFY), transcription factor 12 (TCF12), transcription factor AP-2 gamma (TFAP2C), CCCTC-Binding Factor (CTCF), CCCTC-Binding Factor Like (CTCFL or BORIS),Attorney Docket No. 60448-717.601Myogenin (MY OG), Nuclear transcription factor Y subunit alpha (NFYA), Nuclear transcription factor Y subunit beta (NFYB), Nuclear transcription factor Y subunit gamma (NFY C), Upstream stimulatory factor 1 (USF1), Upstream stimulatory factor 2 (USF2), Jun Proto-Oncogene / AP- 1 Transcription Factor Subunit (JUN), JunD Proto-Oncogene / AP- 1 Transcription Factor Subunit (JUND), Fos Proto-Oncogene / AP- 1 Transcription Factor Subunit (FOS), FOS Uike 1 / AP-l Transcription Factor Subunit (FOSU1), MYC Associated Factor X (MAX), MAF BZIP Transcription Factor F (MAFF), FOS Uike 1 / AP-l Transcription Factor Subunit 2 (FOSU2), FosB Proto-Oncogene, AP-1 Transcription Factor Subunit (FOSB), Nuclear Factor I A, B, C (NFIA, NFIB, NFIC), POU Class 2 Homeobox 2 (POU2F2), Nuclear Receptor Subfamily 3 Group C Member 1, 2 (NR3C1, NR3C2), Kruppel-Uike Factor 7 (KUF7), Neuronal PAS Domain Protein 2 (NPAS2), Basic Helix-Uoop-Helix Family Member E40 (BHUHE40), CAMP Responsive Element Binding Protein 3 Like 2 (CREB3L2), KAT2B (Lysine Acetyltransferase 2B, PCAF, P300 / CBP-associated factor), SMAD6 (SMAD Family Member 6), KLF10 (Kruppel Like Factor 10), TBL1XR1 (F-box-like / WD repeat-containing protein TBL1XR1 or transducin (beta)-like 1 X-linked receptor 1), SOX6 (SRY-Box Transcription Factor 6), SOX9 (SRY-Box Transcription Factor 9), ZNF334 (Zinc Finger Protein 334), ZNF608 (Zinc Finger Protein 608), or a combination thereof. In some instances, the DNA sequence (e.g., genomic sequence) of the transposable element is bound by SPI1 / PU.1. In some instances, the DNA sequence (e.g., genomic sequence) of the transposable element is bound by EBF1.

[0067] In some instances, the transposable element is bound by or targeted by an RNA-binding protein, wherein the transposable element refers to its RNA transcript. In some instances, the RNA-binding protein comprises of DDX3, RBM3, HuR, or a combination thereof.

[0068] In some instances, the transposable element is associated with cardiac fibrosis. In some instances, an RNA expression level of the transposable element is altered in a cell affected by cardiac fibrosis compared to a healthy cell (e.g., healthy cardiac cell of the same individual, healthy cardiac cell of a healthy individual). In some instances, the RNA expression level of the transposable element is increased in a cell affected by cardiac fibrosis compared to a healthy cell. In some instances, the RNA expression level of the transposable element is at least 10%, 20%, 30%, 40%, 50%, 60%, 70, 80%, or 90% more than in a cell affected by cardiac fibrosis compared to a healthy cell. In some instances, the RNA expression level of the transposable element is at least 1.5 folds, 2 folds, 3 folds, 4 folds, 5 folds, 6 folds, 7 folds, 8 folds, 9 folds, or 10 folds higher in a cell affected by cardiac fibrosis compared to a healthy cell. In some instances, the RNA expression level of the transposable element is decreased in a cell affected by cardiac fibrosis compared to a healthy cell. In some instances, the RNA expression level of the transposable element is at least 10%, 20%, 30%, 40%, 50%, 60%, 70, 80%, or 90% lower than inAttorney Docket No. 60448-717.601a cell affected by cardiac fibrosis compared to a healthy cell. In some instances, the transposable element is associated with a differential expression of a marker gene of cardiac fibrosis. In some instances, the marker genes of cardiac fibrosis include smooth muscle α actin (ACTA2), alpha 1 chain of collagen type I (COL1A1), alpha 1 chain of collagen type 3 (COL3A1), fibroblast activation protein (FAP), fibronectin 1 (FN1), periostin (POSTN), collagen triple helix repeat containing 1 (CTHRC1), alpha 1 chain of collagen type 10 (COL10A1), matrix metalloproteinase 11 (MMP11), thrombospondin 2 (THBS2), latent transforming growth factor beta binding protein 2 (LTBP2), Integrin-α11 (ITGA11), or a combination thereof.

[0069] In some instances, the transposable element is associated with dermal fibrosis. In some instances, an RNA expression level of the transposable element is altered in a cell affected by dermal fibrosis compared to a healthy cell. In some instances, the RNA expression level of the transposable element is increased in a cell affected by dermal fibrosis compared to a healthy cell. In some instances, the RNA expression level of the transposable element is at least 10%, 20%, 30%, 40%, 50%, 60%, 70, 80%, or 90% more than in a cell affected by dermal fibrosis compared to a healthy cell. In some instances, the RNA expression level of the transposable element is at least 1.5 folds, 2 folds, 3 folds, 4 folds, 5 folds, 6 folds, 7 folds, 8 folds, 9 folds, or 10 folds higher in a cell affected by dermal fibrosis compared to a healthy cell. In some instances, the RNA expression level of the transposable element is decreased in a cell affected by dermal fibrosis compared to a healthy cell. In some instances, the RNA expression level of the transposable element is at least 10%, 20%, 30%, 40%, 50%, 60%, 70, 80%, or 90% lower than in a cell affected by dermal fibrosis compared to a healthy cell. In some instances, the transposable element is associated with a differential expression of a marker gene of dermal fibrosis. In some instances, the marker genes of dermal fibrosis include smooth muscle α actin (ACTA2), alpha 1 chain of collagen type I (COL1A1), alpha 1 chain of collagen type 3 (COL3A1), fibroblast activation protein (FAP), fibronectin 1 (FN1), periostin (POSTN), collagen triple helix repeat containing 1 (CTHRC1), alpha 1 chain of collagen type 10 (COL10A1), matrix metalloproteinase 11 (MMP11), thrombospondin 2 (THBS2), latent transforming growth factor beta binding protein 2 (LTBP2), Integrin-α11 (ITGA11), or a combination thereof.

[0070] In some instances, the transposable element associated with fibrosis belongs to ERV1, ERV2, or MaLR families. In some instances, the transposable element associated with fibrosis belongs to transposable elements identified in Table 1 or Table 2. In some instances, the transposable element belongs to LTR16, LTR16A, LTR16A1, LTR16A2, LTR16B, LTR16B1, LTR16B2, LTR16C, LTR16D, LTR16D1, LTR16D2, LTR16E1, LTR16E2, ERV3-16A3 LTR, MER39, THE1A, THE1B, THE1C, THE1D, MSTA, MSTA1, MSTB, MSTB1, MSTB2, MSTC, MSTD, MLT1A0, MLT1A1, MLT1C, MLT1D, MLT1E, MLT1E1, MLT1E2, MLT1F,Attorney Docket No. 60448-717.601MLT1F1, MLT1F2, MLT1G1, MLT1G3, MLT1H, MLT1H1, MLT1I, MLT1J, MLT1J1, MLT1J2, MLT1K, MLT1L, MLT1M, MLT1N2, MLT1O, MLT2A1, MLT2A2, MLT2B1, MLT2B2, MLT2B3, MLT2B4, MLT2B5, MLT2C1, MLT2C2, MLT2D, MLT2E, MLT2F, MLT1A, MLT1B, MLT1E1A, MLT1E3, MLT1G, MLT1H2, MLT1C2, MLTIF-int, MST-int, MLT-int, MLT1H-int, MLT1J-int, THEl-int, HERV16, ERVL-E, HERVL, ERVL-B4, ERV3-16A3 I, HERV3, HERVK3, HERVL18, LTR10A, LTR10E, LTR24C, LTR26, LTR40c, LTR44, LTR47B4, LTR8B, LTR90A, MamGypsy2-I, MamRep605, MER21C, MER41B, MER57E3, MER68, MER77B, THElD-int, LTR33, LTR50, LTR78, LTR41, LTR41B, HERV3-int, LTR13, HERVL 18-int, MER66C, MER66D, or LTR19C subfamilies.

[0071] In some instances, the transposable element transcript is transcribed from a sequence comprising at least 60%, at least 70%, at least 80%, at least 90%, or at least 95% identical to at least a portion of a consensus sequence selected from any one of SEQ ID NOs: 4, 7-11, and 14-121. In some instances, the transposable element associated with fibrosis comprises a sequence that is at least 60%, at least 70%, at least 80%, at least 90%, or at least 95% identical to at least a portion of a sequence selected from SEQ ID NOs: 4, 7-11, and 14-121. In some instances, the transposable element transcript is transcribed from a sequence comprising at least 60%, at least 70%, at least 80%, at least 90%, or at least 95% identical to at least a portion of a consensus sequence selected from any one of SEQ ID NOs: 4, 10, 14, 15, 18, 27-32, and 34-38. In some instances, the transposable element associated with fibrosis comprises a sequence that is at least 60%, at least 70%, at least 80%, at least 90%, or at least 95% identical to at least a portion of a sequence selected from SEQ ID NOs: 4, 10, 14, 15, 18, 27-32, and 34-38. In some instances, the transposable element associated with fibrosis comprises a sequence of at least 50%, 60%, at least 70%, at least 80%, at least 90%, or at least 95% identical to SEQ ID NO: 4 or a portion thereof. In some instances, “a portion” as used herein refers to any segments that take up at least 10%, 20%, 30%, 40%, 50%, 60%, 70%, 80%, or 90% the full sequence.

[0072] In some instances, the transposable element associated with fibrosis comprises a sequence of SEQ ID NO: 5. In some instances, the transposable element associated with fibrosis is located around chr3:45818666-45818847. In some instances where the transposable element associated with fibrosis is located around chr3:45818666-45818847, the transposable element associated with fibrosis aligns with the 299thto 489thbase pairs of its consensus sequence (see SEQ ID NO: 4) with about 70% identity and gaps that take up about 8% of the sequence of the transposable element. In some instances, the transposable element associated with fibrosis comprises a sequence of SEQ ID NO: 6. In some instances, the transposable element is located around chr21:42041909-42042242.Attorney Docket No. 60448-717.601Table 1: Table of Sequences DisclosedSEQ SequencesIDNo1 5’- CGGAGGCATGAGGTAG -3’ ASO-1targeting LTR16C on chr3:45,818,66 6-45,818,847 2 5’- TGAGCAGGTTAGCACT -3’ ASO-2targeting LTR16C on chr3:45,818,66 6-45,818,847 3 5’- CTACCTCATGCCTCCG -3’ ASO-3targeting LTR16C on chr3:45,818,66 6-45,818,847 4 TGTAGCAGACGCTGTCGGTGCCCCGCCCATATCCCCTCGGCCCTTA Consensus CCATTTCAGTGCACGCCGGCCCGACTTCCAACTGCCAGCACCTGCA sequence for TCTCTTTGCCTGAGGGCTTTCTCTGGCCGCCGGAGCCCGCTCTGCC transposable CACGCGCANGGCAGGCCGGAAGTGCCGGGGAATTAACGCCCCCCG elements that GGAGCAGCCCTCAACCAATGACTGACGGGAGTTGGTGNATAAATA belong to CCCCAGCTCCCTCGCCCCTCGGGTGGGATAACTCTGAGGCGCGTGT TCTACACTGTCTCCCAGAGTTCCCCAGCGGGATTGAGCTCCAGTTG LTR16C CCCACAGTGGTAACTTGCTCGATAACGCACCCTTTATTGGCTNCCT subfamily TCCCTTCCCTGTCTCACTTCCCCACTCCCCTACCGGTGTTTCCTGGG ATCACCTCCCAAATAAACTACTTGCACTCGAATCCTTGTCTCAGGG TCTGCTTCTGGGGGAACCCAAACTAAGACA5 TCAGTGGGATTGAGCGTGGTGGTCCACAGTGCTAACCTGCTCATTA LTR16C ACACACATTTTATCTCCTTTCTTCCCTTTCCTACCTCATGCCTCCGT within ACCCTCACCCCACTTTCTGGGATCCCCTCCCCACTTCAACCAAGAT chr3:45,818,66 CCCTGCCTCAGGGTTTTGCTTTTGGGGGAGCTGAAATAAAACA 6-45,818,847 6 CTGCCTGTCTTTCCTGAAGACGTTCTCTCTCTGGCCCTGTTCCCAGG LTR16E1 GCAGGCTGAAGGACAAAGGACAGGAAGGTAAGGTCCCAGGAGTG within ACCCCCAGTGTGGAGGATGAGAGTTGTTGGATAAATGTCCCAGCT chr21:42,041,9 CCCTCCTCCCTCCATGGGGCAGTTCTGGGGCATGTTCTGCTCAGAC 09-42,042,242 CTCAATGCAGTCCCAGTGGGATGAACCGAAGTTCCCTCTGGCAGG GATCCTCTCTCTAGGGTACCTGCACTCCTGCCTTCACTGTGCTTCCT GAGATCACCCCCAAAATCAACTGCTTGCCCCCAAATCTTTGTCATA GGGTTTTCAAGAGA7 TGTAGCAGACGCCTCTGGTGCCCCGCGTCACATCCCCTCGGCCCAC Consensus CTCTGATTTCAGCCGCAGCTGCGGTGGACAGTTCCGTGCGAGCTCA sequence for GACTCACCTTTGCTGACAGCGTCCCACCTCAAGCGCGCGCCGTGCG transposable TCTTTCTGCTTTCTGCCCCAGGGCCTTCTCCGACGCCGCGGGAGCC elements that CGCTCGGCCCGCGCGCAAGCGCAGCCCGGAAGTGCGGGGGAGTTA belong to ACGCCCCCGGGGGCAACCCTCAACCAATGGGGGACGGGAGCCGGT GGATAAATGCCCCAGCCTCCCGTCCTTCAGGTGGACAATTCTGGGA LTR16E1 GGCATTCTGTACGCTTCTCAGGAGGTCCCAGCGGGATCGAGCCCC subfamily NGTTGCCCACAGCGGCGACCTCGATAACGCACCCTTATATTGGCTT TTCCTCCTTCCCTGTCTCACTTCCCCGCTCCCTCACTCCTGCTTCCT GGGATCACCTCCCAAATAAACTACCTGCACCCAAGTCCTTGTCTCAGGCTCTGCTTTCGGGGGAACCCAAACTAAGACAGAttorney Docket No. 60448-717.601SEQ SequencesIDNo8 TGATATGGTTTGGCTGTGTCCCCACCCAAATCTCATCTTGAATTGT Consensus AGCTCCCATAATTCCCACGTGTCGTGGGAGGGACCCGGTGGGAGG sequence for TAATTGAATCATGGGGGCGGGTCTTTCCCGTGCTGTTCTCGTGATA transposable GTGAATAAGTCTCACGAGATCTGATGGTTTTATAAAGGGGAGTTCC elements that CCTGCACANGCTCTCTTGCCTGCCGCCATGTAAGACGTGNCTTTGC belong to TCCTCCTTCGCCTTCCGCCATGATTGTGAGGCCTCCCCAGCCACGT GGAACTGTGAGTCCATTAAACCTCTTTCCTTTATAAATTACCCAGT THE1B CTCGGGTATGTCTTTATCAGCAGCGTGAAAACGGACTAATACA subfamily 9 GTAAATTGGTACCAGTAGAGTGGGGCGCTGCTGAAAAGATACCCG Consensus AAAATGTGGAAGCGACTTTGGAACTGGGTAACAGGCAGAGGTTGG sequence for AACAGTTTGGAGGGCTCAGAAGAAGACAGGAAAATGTGGGAAAG transposable TTTGGAACTTCCTAGAGACTTGTTGAATGGCTTTGACCAAAATGCT elements that GATAGTGATATGGACAATAAAGTCCAGGCTGAGGTGGTCTCAGAT belong to GGAGATGAGGAACTTGTTGGGAACTGGAGCAAAGGTGACTCTTGT TATGTTTTAGCAAAGAGACTGGCGGCATTTTGCCCCTGCCCTAGAG THEl-int ATTTGTGGAACTTTGAACTTGAGAGAGATGATTTAGGGTATCTGGC subfamily GGAAGAAATTTCTAAGCAGCAAAGCATTCAAGAGGTGACTTGGGT GCTGTTAAAGGCATTCAGTTTTANAAGGGAAGCAGAGCATAAAAG TTCGGAAAATTTGCAGCCTGACGATGCGATAGAAAAGAAAANCCC ATTTTCTGAGGAGAAATTCAAGCCGGCTGCAGAAATTTGCATAAG TAACGAGGAGCCGAATGTTAATCCCCAAGACAATGGGGAAAATGT CTCCAGGGCATGTCAGAGGCCTTCGCGGCAGCCCCTCCCATCACA GGCCCGGAGGCCTAGGAGGAAAAAATGGTTTCGTGGGCCGGGCCC AGGGTCCCCGTGCTGTGTGCAGCCTAGGGACTTGGTGCCCTGCGTC CCAGCCGCTCCAGCCGTGGCTGAAAGGGGCCAACGTACAGCTCGG GCCGTGGCTTCAGAGGGTGCAAGCCCCAAGCCTTGGCAGCTTCCA CGTGGTGTTGAGCCTGCGGGTGCACAGAAGTCAAGAATTGAGGTT TGGGAACCTCCGCCTAGATTTCAGAGGATGTATGGAAACGCCTGG ATGCCCAGGCAGAAGTTTGCTGCAGGGGCGGGGCCCTCATGGAGA ACCTCTGCTAGGGCAGTGCGGAAGGGAAATGTGGGGTCGGAGCCC CCACACAGAGTCCCTACTGGGGCACCGCCTAGTGGAGCTGTGAGA AGAGGGCCACCGTCCTCCAGACCCCAGAATGGTAGATCCACCGAC AGCTTGCACCGTGCGCCTGGAAAAGCCGCAGACACTCAACGCCAG CCCGTGAAAGCAGCCGGGAGGGAGGCTGTACCCTGCAAAGCCACA GGGGCGGAGCTGCCCAAGACCATGGGAACCCACCTCTTGCATCAG CGTGACCTGGATGTGAGACATGGAGTCAAAGGAGATCATTTTGGA GCTTTAAGATTTGACTGCCCCGCTGGATTTCGGACTTGCATGGGGC CTGTAGCCCCTTTGTTTTGGCCAATTTCTCCCATTTGGAATGGCTGT ATTTACCCAATGCCTGTACCCCCATTGTATCTAGGAAGTAACTAAC TTGCTTTTGATTTTACAGGCTCATAGGCGGAAGGGACTTGCCTTGT CTCAGATGAGACTTTGGACTGTGGACTTTTGAGTTAATGCTGAAAT GAGTTAAGACTTTGGGGGACTGTTGGGAAGGCATGATTGGTTTTG AAATGTGAGGACATGAGATTTGGGAGGGGCCAGGGGCGGAA10 TGTAGTGGATGCTGTGGTGCGCCGCCCAGATCGNNCCCCCCTTCAG Consensus GACCGAGGCACTCATTCCCCCAGCTGCCGGGAGTGTTGGCTGCTG sequence for ACGGCTCNCAGCTGAGTCCCTCTCCGGGAATTGCCCTCGGCCGAA transposable GGGAGCTGCCTCGCCCAAGGTTACGCCCCCTTCCCGGGGGCAGCC elements that CGCATCCAATGACTGGTCGATGCGGGGGTACAAAGGCCTCAGTCC belong to TCAATTCGGGACAACTCTGAAGGGCCATCCCAGCTCCAGAGCTCC CCGTGGGATCGGCTGAGGCCTCTGTTGCGACTGCATCGCAGTTCAA LTR16 CTTCTCCCTCTGCCCAATCCTGCTTCCTTCACTCCCTCACAGGTGTT subfamily GNTCCCGAGAGCACTCCCCAATAAACCTCCTGCACGCAAATCTCCGTCTCAGAGTCTGTTTCCCGGGGAACCCAAttorney Docket No. 60448-717.601SEQ SequencesIDNo11 CATGAGTGGTACCGGGAGTGGTCCGNAGAAAACAGGCGGTAAGAT Consensus GGGGTTTTGGGACTGGCTCACTCACCGCCCGGCGGACAGAGGATA sequence for CCATCCTGGCACAAGGTGGCGGCCCAGTTGCTAAAGATTTCACCG transposable GTGGTGACCTGGGAAAATGTGTCCCAGNNNTTGGAAGGGGAATGC elements that CCTTGCAGGTGCAATGATTCAGGCATTTGAAAGATATGGGGAGAN belong to AATGCCTACAAGGACAGCGGAGTTGGCTGGTTATTGCTAAGTTGT ATTGATGCCCTGCAGAGGGATAATGAGAAACTGAGGGCNGTTAAC ERV3-16A3 I AAGCAGTTAAAGGCTAAGTGTGAGAGCCAGAGGGCCTCTTTGNTG subfamily GTAGCTTACAAAGAGGCCCTTATCTCCTGCAGTGGAAGAGCAGAC ANAGCTGAGGAGCAGACTCAGGATCTAATAGTTAGAGTCGCAGAG CTCCAGAGACGTTTGAATGCTCAGCCAAGGCGAGGTCTGTTATGCT AAAGNTAAGGCCCTTGGTTGGGAAAACCTGGGACGGAACACGGG ATGGGGACATCTGGGTGGATGCCCCCGAAGATNTTGGCTCTCCAG ACTCCTCTGAACCCTCNGAGCCTGCAGAAGTGGCCCACCCCTCCCT ANTAAGAGCTAGCACTCCTCTTGCGCCCGCGCTGGAAGACGNTGC AGAGGCCTCTCCCCGCAAGGCAACAGGTGCCCCCTCTCAGGANCT GCCCCCACCTCCCCTCCTGGCCGCCAGGCCGATAACTAGGGTTAA GTCNCAGCATAACCCGGCTGGGGACGTGCTGGGCCTGATAAGGGA GGAAAGGGACTATACCCCAAAGGAGCTGCAAGAATTAGCCAGCAT GTACCGGCAGGAGCCAGGGGAGTATACNCNTGGGACTGGATTTTG AGGGTGCTTGATCAAGGGGGCCGGAATATAAGCGGTAAGACTGGA TAANGGAAGAATTTATTGACTTGGGAGCACTTTCTCGGGATACAG GATTTAACACCCTGGCAAGGACCCCAGGAGATGGTGCAAACTCGC TGCTAGGATGGCTCCTAGAAGCGAGAAAAATGGCCCACGCTGAGC GAAGTNGAAATGCCNGAATTGCCNTGGCAGACGGTAGAGGAAGG GATTAAAGGCTCAGGGAAGTGGGCATGCTGGAATGGATATNATTA TGTAAGGCCGGAAGACCCACCAGANGATTATGTTCCACGGGAGGG CCCACACCATTCACCAAGGCCATNAGGAATGCGCTGGTGAGAGGG GCACCAGCANNTCACTAAGAAGTTCAGTGGTGGCTCTCCTCTGCA GGCCAGGGCTGACGGTAGGAGAGGCCGTTACAGAACTGGGCTCGC TGATAGCAATGGGGATGATAGGACCCCGAAACAATAGAGGCCAG GTGGCGGCGCTTAACCGCCAGAAGCCAGGNGGNCGCAATTATCGT AATGACCGGAAGGTCGGAGTGGCAGCCAAGGGGGCCTGACCCAA GAGAGTTGTGGAGATGGTTAATAGAACACGGCGTCCCTAGGGGCA AAATAGATNGACAAGGGTGCTGCTTAACTTGTAACAGCAGAAAAA ATCTGGGAGGCTGAGGGCGGTCGCCCCAATAAAAAAGTCACGATC CCTTGCCCAGTTTCCGGACCTGAGCCAGTTTTCAGACCCGGAACCC ATTGACTGAAGAGGNGGCCGGGTCCCCAGGAGGAAGGACACTGC AATGATTCTTCTCNTTCCTCCCGNAGGGACCTATGGCCATTTACTC GGGTAACTGTACACTGGGGAAAGGGAATACCCAGACATTTCGAGG ACTGTTGGACACAGGGTCTGAGTTGACATTGATACCCGGAGACCC GAAGCGTCATCATGGCCCCCTGTTAGAGTGGGGGCATATGGGGGC CAGGTAATAAATGGAGTCCTGGCCAAGGTCCGGCTCACAGTGGGT CCACTGGGTCCANGAACCCAGTGGTCATTTCCCCGGTCCCCGAATG TATAATTGGGTAGTTGGAGTAACCCCCACATTGGNTCCTTGGCCTG TGGGGTAAGAGCTATCATAGTGGGGAAGGCCAAGTGGAAGCCTCT GAAACTGCCCNCCNCCNCCATTCCTAGCCAAGATAGTAAATTATTA TATCCTCTCGAGGAAGTGGCGGATGCAGATTAGTGCCACCNTTAA AGACCTAAAGGATGCAGGGGTGGTGGTCCCCATCATATCTCCATTT AATTCACCAGTCTGGCCCCTGCAGAAACCGGATGGATCCTGGAGA ATGACNGTAGACTACCGCAAACTCAACCAAGTAGTAGCCCCGATT GCAGCTGCTGTGCCAGATGTGGTATCTTTGCTAGAGCAGATTAACA CGGCCTCAGGTACATGGTATGCGGCCATTGATTTGGCGAATGCGTTCTTTTCCATTCCNATCAGAAAAGAGGATCAGAAACATTCACATGAAttorney Docket No. 60448-717.601SEQ SequencesIDNo ACAGGAAANAATATACATTTACAGTTTTGCCCCAGGGCTATGTTAT CTTCTCCTCTGTCATAATAAGTCCGAAGAGATCTGGACCGTCTGGA CATCCCGCAGAACATCACATTGATCCATTACATCGATGACATCATG CTGATCGGACNGGATGAGCAAGAGGTGGCTACGTTAGGCCTTGGT AAGACACATGCGCTGAGGGTGGAGATAACCCTACGAAGATTCAGC GNNNGGACCTGCCACNTCAGTAAAGTTTTTAGGGGTCCAGTGGTC NGGGGCATGCCGGGACATCCCCTCCAAAGTAAAAGACAAATTGTT GCATCTTGCATCTCCTACCACGAAGAAGGAAGCACAACGCCTGGT AGGCCTCTTTGGGTTCTGGAGGCAGCATATTCCACACCTGGGAATA CTGCTCCGGCCCATNTACCGGGTGACACGGAAGGCTGCCAGCTTT GAGTGGGCCCAGAGCAGGAAAGGGCTCTGCAGCAGGTCCAGGCTG CGGTGCAAGCAGCCCTGCCGCTTGGGCCATACGACCCGGCAGACC CTATGGTGTTGGAGGTGTCAGTGGTGGGAAAAGATGCNGTGTGGA GTTTATGGCAAGCCCCAGTGGGAGAATCACAACGCAGGCCCCTGG GGTTCTGGAGCAAGGCTGCAAGTCTTTTGAAAAACAGCTCTTNNN ATGCTACTGGTAGAGANGGAACGCTTACCATGGGACACCAAGTGA CACGNANCAAAATGTACCCCGTCATGAGCTGGGTTCTGTCGGACC CACCAAGTCATAAGGTCGGGCGGGCCCAGCAGCAATCCATCGTAA GATGGAAGTGGTACATCCGGGATCGAGCACGAGGAGGACCACAA GTAAGCTGCATGAGCAGGTAGCCCAGACCCCCATGTCACCCACCA CNGTTGCACCAGCGCTCCTTCAGCTCACACCTATGGCCGTATGGAG NAGAGGTGTGNTCCTGATCGACCAGCTGAAGGAGGAGGAAAAAN GCCCGAGCTTGGTTCACGGATGGGTCGGCTCGGTATGTGGGTGCA AGCCGAAAATGGACGGCGGCTTGCACTACAGCCNCACTCAGGGGT GGCCTTGAAAGACAGTGGNGAGGGAAAATCTTCCCAATGGGCAGA GCTTCGGGCGGTGCACCTGGTCATCCACTTTGTGTGGAAGGAGAA GTGGCCCGAGGTNAGAATATATACGGACTCATGGGCAGTGGCGAA TGGCTTGGCCGGCTGGTCAGGGGCCTGGAAGGAGAAAGATTGGAA GATCGGAGACAAGGAGGTCTGGGGANTAGAGGCATGTGGATGGA CNTATGGGAGTGGGCACGAAGTGTGAAGATCTTTGTATCACATGTT AACGCCCACCAGAGAGCATCCACCACGGAAGAGGCACTAAACAA CCAAGTAGACAAAATGACTCGGCCAGTTGACGTCAGCCAGCCTCT GTCATCGGCCACCCCANGTGCTGGCACAATGGGCACATGAACGGA GTGGCCACGGTGGCAGAGATGGAGGCTACGCATGGGCCCAACAGC ATGGACTCCCACTCACCAAGGCTGATCTAGCTACTTGCTGCCNCNN CTGAATGTCCAACCTGCCAGCAACAGAGACCGATCCCCGATATGG CACCATTCCTCGAGGAGACCAACCAGCCACTTGGTGGCAAGTTGA CTACATTGGGCCCCTTCCATCCTGGAAGGGNCAGCGGTTCATCCTN ACAGGAATACATATTCCGGGTATGGGTTTGCCTTTCCTGCCCGCAG GGCCTCAGCCAGCACCACTATCCGAGGGCTTACGGAGTGCCTGAT CCACNGGCATGGGATCCCACACAACATNGCATCNGACCAGGGACC CACTTTACAGCAAAGGAGGTGCGGGAGTGGGCCCATGACCATGGG ATCCACTGGTCNTATCACATACCGCACCATCCAGAAGCTGCCGGCC TGATAGAGCGNTGGAACGGCCTNCTGAAGGCACAGCTGAAGCGCC AGCTCGGAGACGATACTCTGCGAGGATGGGGCGCCATCCTTCAGG ATGCAGTGTCCCCAATAGGAAGAATACATGGGTCCGGGAACCAAG GGGTGGAAGCAGGAGTGTNGCCCCACTTACCATCACTCCCAGTGA CCCACTGGGGGANTTTGTGCTTCCCGTCCCCGCAACTCTGGGCTCT GCAGGNTTAGAGGTCCTGGTCCCCAAAGGGGGNACGCTCTCGCCA GGGGACACAGCGTCCCATTGAACTNTANAGCTACGGCTGCCGCCT GGGCACTTTGGGCTCCTTGTGTCCAGGGACCAGCAGGCAAGAAGA GGAGTCACCATCTTGGCAGGGGTAATTGACCCTGATCATCAGGAG GAGGTAGGGCTGCTNTTACACAATGGGGGCAGGGAGGAATACGTNTGGAACCCAGGTGATCCACTTGGGCGCCTCTTGGTACTCCCTTGCCAttorney Docket No. 60448-717.601SEQ SequencesIDNoCAATTNTGACTGTAAATGGACAAGTGCAGCAACCCCGGCCTGAGA AGGGCATGGTNACCAGGGGCTCAGACCCCTCAGGAATGAGGGTCT GGGTCACGCCACCAGGTAAGCCACCGAGACCAGCAGAGTGNTAGC TGAGGGTGAGGGGAATCTAGAATGGATAGTGGAGGAGGGAGACG ATGAGTATCAGTTGCGGCCCCGAGACCAACTGAGCGACGGGGGCT GTAGTTCGTCCCACTAACCTCCCTCTTCTAAGTTTCCCTCAGGAAG AGAGGCCCACNGGAATCCTGGAGGAGCTGCTCCTGAACCGAACGT GTATGGAGAAGTGGATCCGNGCGGCGCAAGGGGTGGAC12 CCACAGTGCTAACCTGCTCA Primer for LTR16C within chr3:45,818,66 6-45,818,847 13 TCCCCCAAAAGCAAAACCCT Primer for LTR16C within chr3:45,818,66 6-45,818,847 14 CATGAGTGGTACCGGGAGTGGTCCGNAGAAAACAGGCGGTAAGAT Consensus GGGGTTTTGGGACTGGCTCACTCACCGCCCGGCGGACAGAGGATA sequence for CCATCCTGGCACAAGGTGGCGGCCCAGTTGCTAAAGATTTCACCG transposable GTGGTGACCTGGGAAAATGTGTCCCAGNNNTTGGAAGGGGAATGC elements that CCTTGCAGGTGCAATGATTCAGGCATTTGAAAGATATGGGGAGAN belong to AATGCCTACAAGGACAGCGGAGTTGGCTGGTTATTGCTAAGTTGT ATTGATGCCCTGCAGAGGGATAATGAGAAACTGAGGGCNGTTAAC ERV3-16A3 I AAGCAGTTAAAGGCTAAGTGTGAGAGCCAGAGGGCCTCTTTGNTG subfamily GTAGCTTACAAAGAGGCCCTTATCTCCTGCAGTGGAAGAGCAGAC ANAGCTGAGGAGCAGACTCAGGATCTAATAGTTAGAGTCGCAGAG CTCCAGAGACGTTTGAATGCTCAGCCAAGGCGAGGTCTGTTATGCT AAAGNTAAGGCCCTTGGTTGGGAAAACCTGGGACGGAACACGGG ATGGGGACATCTGGGTGGATGCCCCCGAAGATNTTGGCTCTCCAG ACTCCTCTGAACCCTCNGAGCCTGCAGAAGTGGCCCACCCCTCCCT ANTAAGAGCTAGCACTCCTCTTGCGCCCGCGCTGGAAGACGNTGC AGAGGCCTCTCCCCGCAAGGCAACAGGTGCCCCCTCTCAGGANC TGCCCCCACCTCCCCTCCTGGCCGCCAGGCCGATAACTAGGGTTAA GTCNCAGCATAACCCGGCTGGGGACGTGCTGGGCCTGATAAGGGA GGAAAGGGACTATACCCCAAAGGAGCTGCAAGAATTAGCCAGCAT GTACCGGCAGGAGCCAGGGGAGTATACNCNTGGGACTGGATTTTG AGGGTGCTTGATCAAGGGGGCCGGAATATAAGCGGTAAGACTGGA TAANGGAAGAATTTATTGACTTGGGAGCACTTTCTCGGGATACAG GATTTAACACCCTGGCAAGGACCCCAGGAGATGGTGCAAACTCGC TGCTAGGATGGCTCCTAGAAGCGAGAAAAATGGCCCACGCTGAG CGAAGTNGAAATGCCNGAATTGCCNTGGCAGACGGTAGAGGAAG GGATTAAAGGCTCAGGGAAGTGGGCATGCTGGAATGGATATNATT ATGTAAGGCCGGAAGACCCACCAGANGATTATGTTCCACGGGAGG GCCCACACCATTCACCAAGGCCATNAGGAATGCGCTGGTGAGAGG GGCACCAGCANNTCACTAAGAAGTTCAGTGGTGGCTCTCCTCTGC AGGCCAGGGCTGACGGTAGGAGAGGCCGTTACAGAACTGGGCTCG CTGATAGCAATGGGGATGATAGGACCCCGAAACAATAGAGGCCAG GTGGCGGCGCTTAACCGCCAGAAGCCAGGNGGNCGCAATTATCGT AATGACCGGAAGGTCGGAGTGGCAGCCAAGGGGGCCTGACCCAA GAGAGTTGTGGAGATGGTTAATAGAACACGGCGTCCCTAGGGGCAAAATAGATNGACAAGGGTGCTGCTTAACTTGTAACAGCAGAAAAAAttorney Docket No. 60448-717.601SEQ SequencesIDNo ATCTGGGAGGCTGAGGGCGGTCGCCCCAATAAAAAAGTCACGATC CCTTGCCCAGTTTCCGGACCTGAGCCAGTTTTCAGACCCGGAACCC ATTGACTGAAGAGGNGGCCGGGTCCCCAGGAGGAAGGACACTGC AATGATTCTTCTCNTTCCTCCCGNAGGGACCTATGGCCATTTACTC GGGTAACTGTACACTGGGGAAAGGGAATACCCAGACATTTCGAGG ACTGTTGGACACAGGGTCTGAGTTGACATTGATACCCGGAGACCC GAAGCGTCATCATGGCCCCCTGTTAGAGTGGGGGCATATGGGGGC CAGGTAATAAATGGAGTCCTGGCCAAGGTCCGGCTCACAGTGGGT CCACTGGGTCCANGAACCCAGTGGTCATTTCCCCGGTCCCCGAATG TATAATTGGGTAGTTGGAGTAACCCCCACATTGGNTCCTTGGCCTG TGGGGTAAGAGCTATCATAGTGGGGAAGGCCAAGTGGAAGCCTCT GAAACTGCCCNCCNCCNCCATTCCTAGCCAAGATAGTAAATTATTA TATCCTCTCGAGGAAGTGGCGGATGCAGATTAGTGCCACCNTT AAAGACCTAAAGGATGCAGGGGTGGTGGTCCCCATCATATCTCCA TTTAATTCACCAGTCTGGCCCCTGCAGAAACCGGATGGATCCTGGA GAATGACNGTAGACTACCGCAAACTCAACCAAGTAGTAGCCCCGA TTGCAGCTGCTGTGCCAGATGTGGTATCTTTGCTAGAGCAGATTAA CACGGCCTCAGGTACATGGTATGCGGCCATTGATTTGGCGAATGC GTTCTTTTCCATTCCNATCAGAAAAGAGGATCAGAAACATTCACAT GAACAGGAAANAATATACATTTACAGTTTTGCCCCAGGGCTATGTT ATCTTCTCCTCTGTCATAATAAGTCCGAAGAGATCTGGACC GTCTGGACATCCCGCAGAACATCACATTGATCCATTACATCGATGA CATCATGCTGATCGGACNGGATGAGCAAGAGGTGGCTACGTTAGG CCTTGGTAAGACACATGCGCTGAGGGTGGAGATAACCCTACGAAG ATTCAGCGNNNGGACCTGCCACNTCAGTAAAGTTTTTAGGGGTCC AGTGGTCNGGGGCATGCCGGGACATCCCCTCCAAAGTAAAAGACA AATTGTTGCATCTTGCATCTCCTACCACGAAGAAGGAAGCACAAC GCCTGGTAGGCCTCTTTGGGTTCTGGAGGCAGCATATTCCACACCT GGGAATACTGCTCCGGCCCATNTACCGGGTGACACGGAAGGCT GCCAGCTTTGAGTGGGCCCAGAGCAGGAAAGGGCTCTGCAGCAGG TCCAGGCTGCGGTGCAAGCAGCCCTGCCGCTTGGGCCATACGACC CGGCAGACCCTATGGTGTTGGAGGTGTCAGTGGTGGGAAAAGATG CNGTGTGGAGTTTATGGCAAGCCCCAGTGGGAGAATCACAACGCA GGCCCCTGGGGTTCTGGAGCAAGGCTGCAAGTCTTTTGAAAAACA GCTCTTNNNATGCTACTGGTAGAGANGGAACGCTTACCATGGGAC ACCAAGTGACACGNANCAAAATGTACCCCGTCATGAGCTGGGTTC TGTCGGACCCACCAAGTCATAAGGTCGGGCGGGCCCAGCAGCAAT CCATCGTAAGATGGAAGTGGTACATCCGGGATCGAGCACGAGGAG GACCACAAGTAAGCTGCATGAGCAGGTAGCCCAGACCCCCATGTC ACCCACCACNGTTGCACCAGCGCTCCTTCAGCTCACACCTATGGCC GTATGGAGNAGAGGTGTGNTCCTGATCGACCAGCTGAAGGAGGAG GAAAAANGCCCGAGCTTGGTTCACGGATGGGTCGGCTCGGTATGT GGGTGCAAGCCGAAAATGGACGGCGGCTTGCACTACAGCCNCACT CAGGGGTGGCCTTGAAAGACAGTGGNGAGGGAAAATCTTCCCAAT GGGCAGAGCTTCGGGCGGTGCACCTGGTCATCCACTTTGTGTGGA AGGAGAAGTGGCCCGAGGTNAGAATATATACGGACTCATGGGCAG TGGCGAATGGCTTGGCCGGCTGGTCAGGGGCCTGGAAGGAGAAA GATTGGAAGATCGGAGACAAGGAGGTCTGGGGANTAGAGGCATG TGGATGGACNTATGGGAGTGGGCACGAAGTGTGAAGATCTTTGTA TCACATGTTAACGCCCACCAGAGAGCATCCACCACGGAAGAGGCA CTAAACAACCAAGTAGACAAAATGACTCGGCCAGTTGACGTCAGC CAGCCTCTGTCATCGGCCACCCCANGTGCTGGCACAATGGGCACA TGAACGGAGTGGCCACGGTGGCAGAGATGGAGGCTACGCATGGGCCCAACAGCATGGACTCCCACTCACCAAGGCTGATCTAGCTACTTGCAttorney Docket No. 60448-717.601SEQ SequencesIDNoTGCCNCNNCTGAATGTCCAACCTGCCAGCAACAGAGACCGATCCC CGATATGGCACCATTCCTCGAGGAGACCAACCAGCCACTTGGTGG CAAGTTGACTACATTGGGCCCCTTCCATCCTGGAAGGGNCAGCGG TTCATCCTNACAGGAATACATATTCCGGGTATGGGTTTGCCTTTCC TGCCCGCAGGGCCTCAGCCAGCACCACTATCCGAGGGCTTACGG AGTGCCTGATCCACNGGCATGGGATCCCACACAACATNGCATCNG ACCAGGGACCCACTTTACAGCAAAGGAGGTGCGGGAGTGGGCCCA TGACCATGGGATCCACTGGTCNTATCACATACCGCACCATCCAGA AGCTGCCGGCCTGATAGAGCGNTGGAACGGCCTNCTGAAGGCACA GCTGAAGCGCCAGCTCGGAGACGATACTCTGCGAGGATGGGGCGC CATCCTTCAGGATGCAGTGTCCCCAATAGGAAGAATACATGGGTC CGGGAACCAAGGGGTGGAAGCAGGAGTGTNGCCCCACTTACCATC ACTCCCAGTGACCCACTGGGGGANTTTGTGCTTCCCGTCCCCGCA ACTCTGGGCTCTGCAGGNTTAGAGGTCCTGGTCCCCAAAGGGGGN ACGCTCTCGCCAGGGGACACAGCGTCCCATTGAACTNTANAGCTA CGGCTGCCGCCTGGGCACTTTGGGCTCCTTGTGTCCAGGGACCAGC AGGCAAGAAGAGGAGTCACCATCTTGGCAGGGGTAATTGACCCT GATCATCAGGAGGAGGTAGGGCTGCTNTTACACAATGGGGGCAGG GAGGAATACGTNTGGAACCCAGGTGATCCACTTGGGCGCCTCTTG GTACTCCCTTGCCCAATTNTGACTGTAAATGGACAAGTGCAGCAAC CCCGGCCTGAGAAGGGCATGGTNACCAGGGGCTCAGACCCCTCA GGAATGAGGGTCTGGGTCACGCCACCAGGTAAGCCACCGAGACCA GCAGAGTGNTAGCTGAGGGTGAGGGGAATCTAGAATGGATAGTGG AGGAGGGAGACGATGAGTATCAGTTGCGGCCCCGAGACCAACTGA GCGACGGGGGCTGTAGTTCGTCCCACTAACCTCCCTCTTCTAAGT TTCCCTCAGGAAGAGAGGCCCACNGGAATCCTGGAGGAGCTGCTC CTGAACCGAACGTGTATGGAGAAGTGGATCCGNGCGGCGCAAGGG GTGGAC15 TGTGGCAGCCACGGAGGTGCGCCGCTCGGATCTCCCTTCAAGAAA Consensus GAACTTGCCGTTCAGCTGCGAGGAGTGCGGTTAGCTGACAGCCTC sequence for CAGCTGTTAGCGCCTTCAGGATCCGCCTCAGCTTTCGAGCCGAGGC transposable CACGCTCTTCCCGGGCAGCCCCCAGCCAATGACTGAGCANGGCG elements that GGGGTACNAGGGCCTGGCCATTTCTGCCCAACGCGGGACTCCTCT belong to AACGGGCAATCTTTGCTCCGGAAGAGCTCCCCGTTGGGTTGGCCG AGACTTTGTCAGATCTGCATCGCGGTCTGAGGCTCTCCCTGCCCAA ERV3- TCCTGCTTCCTCTCCTTTTNTCTTTCACAGGCGTTACCCCCCAA 16A3 LTR TAAACCTCTTGCACTCCTAACTCCGTCTCAGCGTCTGCTTCCCGGA subfamily GGACCCAACTGACACA16 GATTTTGGTACCGAGAGTGGTTCTAGAGGAACAGAATTTTAAGGA Consensus TGAGTTTTCTGAATTGGTTCTGGGGTTTCTGGAATTGGCTCTCTA sequence for ATCTGATTAGATTTAAAGACGCTAATGACTCTATTTCCAGTAGTAA transposable AGAGAGCACTGATAGTCCATGGCGTGATCTGGCAATAGAGATAC elements that GCAAAATATCNCCATTGGATACTCCTAATCAACCACTTATAAGAA belong to GCAAGGANCTGGGTGACTNTGTATATGATACTTTCGAACATTTTT GGNAAACTAACGAATATAATGAGATTGGCTGGTTGCTCCTAATGT ERVL-B4 CGCTGGACAAAGTGGNGAAAGAAAAGGATGAGCTCAGGGATTCG subfamily AATTCCCAGCTCAAGCGCCGCATAAATGACCTGAAAGCTTCTATGT GTGCCCTGAAGGAGACCCTTATCTCCTGTAGCCGCAGGGCTGAGA TTGCTGAAAATCAAACGCAGAATCTCATCCTGCGACTGGCTGAATT ACAACGCAAGTTGAACTCCCAGCCTCGCAGGGTGTCTACTGTTA AAGTGAGGGCATTGATTGGGAAAGAATGGGATCCTGNAAGTTGGA ATGGGGACGTGTGGGAAGACCCTGATGAAGCTGGGGACATTGAGC CCCTAAATTCTGATGAGTCTTCTTTGCCAGTGGAAGNGGCCTCCCCACCCCCAGTGGAAGCGGCCTCCCCACCCCCAGTGGTAGCGGCCTAttorney Docket No. 60448-717.601SEQ SequencesIDNo CTCCACCCCCGTCTGAGGGGATTAACCCTGCATTGCCTGAGGAAAC TGTAATGGCCTCCCCTGAGGCAGTTGCCATGCAAGACAATGCTG ATTCTCCTCAGGACCCACCCCCACCACCCCTCTTTGCTTCTAGACC TATAACTAGACTCAAGTCCCAGCAGGCCCCTAAAGGTGAGGTAC AAAGTGTGACCCATGAGGAGGTGCGCTACACTCCAAAAGAACTAC TTGAGTTTTCTAATTTATACAGACAGAAATCCGGGGAACATGTGT GGGAATGGATATTAAGGGTGTGGGATAATGGTGGAAGGAACATAA AGTTGGATCAGGCCGAATTTATTGATATGGGCCCACTAAGCAGAG ATTCTGCATTTAATGTTGCAGCTCGGGGAGTTAGAAAGGGCTCTAA CAGTTTGTTTGGTTGGTTGGCTGAAACATGGACCAAAAGGTGGC CCACAGTGAGCGAATTGGAAATGCCGGACCTGCCTTGGTTTAATGT AGAGGAAGGGATTCAAAGGCTTAGGGAGATTGGAATGTTAGAGT GGATTTGTCATTTAAGACCTACTCACCCACACTGGGAGGGTCCAGA AGACATACCTTTCACCANNACTGTGAGAAATAAATTTGTGAGGG GAGCCCCAGCATCCTTGAAGAGCTCTGTGATCGCTCTTCTCTGTAG GCCAGACCTTACAGTGGGAACTGCAGCCACTGAATTGGGAAACC TAAATGCAATGGGAGTAATTGGATCCCGGGGTGGCAGGGGCCAAG TGGCGGCACTCAACCGCCAAAGGCAAGGTGGGCGTGGTTACCGTA ATGGACAGCAGAGTCAAAGCAGCAATCAGAATAGTCTGACTCGCG CAGACCTATGGCGTTGGCTAGTTGATCATGGTGTTCCTAGAAGTG AAATAGATAGGAAGCCTACTAAATTCTTACTTGATCTGTATAAGCA GAAAAGTTCTAGGTCAAGTGAACAAAAGTCTAACTTGAATCATA AAAACAGAGAGTCACGGCCCCTCAATCAATTCCCAGACTTGAGCC AGTTTACAGACCCAGAACCCCTTGAATGAAGGGGAGGCCGGGTCC CCTTGAGGAAGGACCCCGGTACACTGCCAAAAATTTATACTGTTA ATCTTTCTCCCAGCCTTCCCCAAAGGGACCTACGGCCTTTTACCA GGGTAACTGTGCATTGGGGAAAAGGAAATAATCAGACCTTTCGGG GACTACTGGACACTGGCTCTGAACTGACACTAATTCCAGGAGACC CAAAACGTCACTGTGGTCCACCAGTCAGAGTAGGGGCTTATGGAG GTCAGGTGATCAATGGAGTTTTAGCTCAGGTCCGTCTCACAGTGG GCCCAGTGGGTCCCCGAACCCATCCTGTGGTTATTTCCCCAGTTCC GGAATGCATAATTGGAATAGACATACTCAGCAGCTGGCAGAATC CCCACATTGGTTCCCTGACCTGTGGAGTGAGGGCTATTATGGTGGG AAAGGCCAAGTGGAAGCCACTAGAACTGCCTCTACCTAGGAAAA TAGTAAACCAAAAGCAATACCGCATTCCTGGAGGGATTGCAGAGA TTAGTGCCACCATCAAGGACTTGAAAGATGCAGGGGTGGTGATTC CCACCACATCCCCATTCAACTCGCCTATTTGGCCTGTGCAGAAGAC AGATGGATCTTGGAGAATGACAGTGGATTATCGTAAGCTTAACC AGGTGGTGACTCCAATTGCAGCTGCTGTACCAGATGTGGTTTCATT GCTTGAGCAAATTAACACATCCCCTGGTACCTGGTATGCAGCTA TTGATCTGGCAAATGCCTTTTTCTCCATACCTGTCAATAAGGNCCA CCAGAAGCAGTTTGCTTTCAGCTGGCAAGGCCAGCAATACACCT TCACTGTCCTACCTCAGGGGTATATCAACTCTCCAGCCCTATGTCA TAATTTAGTTCGCAGGGATCTTGATCGCCTTTCCCTTCCACAAG ATATCACACTGGTCCATTACATTGATGACATTATGCTGATTGGACC TAGTGAGCAAGAAGTAGCAACTACTCTAGACTTATTGGTAAGAC ATTTGCGTGTCAGAGGGTGGGAAATAAATCCGACAAAAATTCAGG GGCCTTCTACCTCAGTGAAATTTCTAGGGGTCCAGTGGTGTGGGG CATGTCGAGATATCCCTTCTAAGGTGAAGGATAAGTTGTTGCATCT GGCCCCTCCTACAACCAAAAAAGAGGCACAATGCCTAGTGGGCC TCTTTGGATTTTGGAGGCAACATATTCCTCATTTGGGTGTGTTACTC CGGCCCATTTACCGAGTGACCCGAAAAGCTGCTAGTTTTGAGT GGGGCCCAGAACAAGAGAAGGCTCTGCAACAGGTCCAGGCTGCTGTGCAAGCTGCTCTGCCACTTGGGCCATATGATCCAGCAGATCCAAAttorney Docket No. 60448-717.601SEQ SequencesIDNo TGGTGCTTGAAGTGTCAGTGGCAGATAGGGATGCTGTTTGGAGCCT TTGGCAGGCCCCTATAGGTGAATCGCAGCGCAGGCCCTTAGGAT TTTGGAGCAAAGCCCTGCCATCCTCTGCAGATAACTACTCTCCTTT TGAGAAACAGCTCTTGGCCTGCTACTGGGCCTTAGTAGAGACTG AACGCTTAACCATGGGCCACCAAGTTACCATGCGACCTGAGCTGC CCATCATGAACTGGGTGTTATCTGACCCACCAAGCCATAAAGTTG GGCGTGCACAGCAGCACTCCATCATCAAATGGAAGTGGTATATAC GTGATCGGGCCCGAGCAGGCCCTGAAGGCACAAGTAAGTTACATG AAGAAGTGGCCCAAATGCCCATGGTCCCCACTCCTGCTACACTGCC TTCTCTCTCCCAGCCTGCACCTATGGCCTCATGGGGAGTTCCCT ACGATCAGTTGACAGAGGAAGAGAAGACTCGGGCCTGGTTTACAG ATGGTTCTGCACGATATGCAGGCACCACCCGAAAGTGGACAGCTG CAGCACTACAGCCCCTTTCTGGGACATCCCTGAAGGACAGTGGTG AAGGGAAATCCTCCCAGTGGGCAGAACTTCGAGCAGTGCACCTGG TTGTTCACTTTGCTTGGAAGGAGAAATGGCCAGACGTGCGATTATA TACCGATTCATGGGCTGTGGCCAATGGTTTGGCTGGATGGTCAG GGACTTGGAAGGAACATGATTGGAAAATTGGTGACAAGGAAATTT GGGGAAGAGGTATGTGGATAGACCTCTCTGAATGGGCAAAAAACG TGAAGATATTTGTGTCCCATGTGAATGCTCACCAAAGGGTGACCTC AGCAGAGGAGGATTTTAATAATCAAGTGGATAGGATGACCCGTT CTGTGGATACCAGTCAGCCTCTTTCCCCAGCCACCCCTGTCATCGC CCAATGGGCTCATGAACAAAGTGGCCATGGTGGCAGGGATGGAG GTTATGCATGGGCTCAGCAACATGGACTTCCACTCACCAAGGCCG ACCTGGCTACGGCCACCGCTGAGTGCCCAATCTGCCAGCAGCAGA GACCAACACTGAGTCCCCGATATGGCACCATTCCCCGGGGTGATC AGCCAGCTACCTGGTGGCAGGTTGATTACATTGGACCGCTTCCAT CATGGAAGGGGCAGCGTTTTGTTCTTACTGGAATAGACACTTACTC TGGATACGGATTTGCCTTCCCTGCACGCAATGCTTCTGCCAAAA CTACCATCCGTGGACTTACAGAATGCCTTATCCACCGTCATGGTAT TCCACACAGCATTGCTTCTGATCAAGGAACTCACTTCACAGCAA ANGAAGTGCGGCAATGGGCCCATGCTCATGGAATTCACTGGTCTT ACCATGTTCCCCACCATCCTGAAGCAGCTGGCTTGATAGAACGGT GGAATGGCCTTTTGAAGACTCAGTTACAGCGCCAGCTAGGTGGCA ATACCTTGCAGGGCTGGGGCAAGGTTCTCCAGAAGGCTGTATATG CTCTGAATCAGCGTCCAATATATGGTGCTGTTTCTCCCATAGCCAG GATTCACGGGTCCAGGAATCAAGGGGTGGAAATGGGAGTGGCAC CACTCACTATTACCCCTAGTGACCCACTAGCAAAATTTTTGCTTCC TGTTCCCGCGACCTTATGCTCTGCTGGCCTAGAGGTCTTAGTTC CAAAGGGAGGAATGCTTCCACCAGGAGACACAACAATGATTCCAT TGAACTGGAAGTTAAGACTGCCACCCGGCCACTTTGGGCTCCTCA TGCCTCTGAATCAACAGGCAAAGAAGGGAGTTACTGTGCTGGCTG GGGTGATTGATCCTGACTACCAAGGGGAAATTGGACTGCTACTCC ACAATGGAGGTAAGGAAGAGTATGTCTGGAATACAGGAGATCCCT TAGGGCGTCTCTTAGTATTACCATGCCCTGTGATTAAGGTCAATG GAAAACTACAACAACCCAATCCAGGCAGGACTACTAATGGCCCAG ACCCTTCAGGAATGAAGGTTTGGGTCACCCCACCAGGTAAAGAAC CACGACCAGCTGAGGTGCTTGCTGAAGGCAAAGGGAATACGGAAT GGGTAGTGGAAGAAGGTAGTTATAAATACCAGCTACGACCACGTG ACCAGTTACAGAAACGAGGACTGTAATTGTCATGAGTATTTCCTCC TTATTTTGTTATGAATATGTTTGTGTGTATATATACATATATTA AGCAAATATCTTTGTTTTCTTTCCTCTCTTATTCCCTTATCATGTAA CATAAGATGTATTGACTTTATATCATAGTATTTAAGTATTGTT AATTTTACATCATAGTATTTAAGTTACGGGATATCAAGGAGAAGAGTAAACATCACTCAAGGACTTTACCTCCTCTTCTGGGGAAGGGGTAttorney Docket No. 60448-717.601SEQ SequencesIDNoTAGTGCGTTTTCGGTTGTACGCAGGATAGTTGTATCATGTTAGGCG GAATTATGACCTTGTTATTGTCTTTATTTGGAGATTAAGTATGG TTTAAGGAGATGCGTATGGGTGCCAAGTTGACAAGGGGTGGACT17 ATTATTGGTACCGGGAGTGGTTCCAGGGGAACAGAACCTTAAGGA Consensus TGGGAATCTGGAATTGGTTCTCTGATCTGATTAGATTTAAAGGCG sequence for CTAATGACCCTGTTTCCAGTGGTAAAGGGGACACTGGTAGTCCATG transposable GCATGCAGTGGCAAAAAGTTACTCAAATTATCACCTGTGGNCAC elements that CTGTAATCAAGTGCCTATAGAAGGCAAGGCTTTGGGTGACCANGT belong to ANTTGCTGCCNTAGAACATTTTAGTGGAAATAAGGAGTATAATGA NGTTGGTTGGTTGCTTCTAANTGCGCTGGAGAACTTGGAGAAAGA ERVL-E AAATGATGAGCTCAGGGCTTTAAATTCCCAGCTCAAGNTCCGGGT subfamily AAGGGACCNGAAAGCTTCTATGACTGCCCTGAAAGAAACCCTTAT CTCCTGTAGCCGCAGGGCTGAGATTTCTGAAAACCAAACCCAAAG TCTNATCCTGCGGGTGGCTGAATTACAACGCAAATTGAATTCNCAA CCTCGCAGGGTNTCTTNTGTTAAAGTTAGGGCATTGATTGGGAA GGAATGGGACCCTGAAAATTGGAATGGGGACATNTGGGCGGATTC CGATGAAGCTGGGGACCTTGAACCCCTAAATTCTGCCGAGCCTTC TTTGCCAGTAGAAGCAGCCCTTTCNCCCCTGTCTGAGGAGGTTAGT CTCCCCTTGCCTGAAGAANCTGTAATGGCCTCCCCTGAGGTAGT TGCCTTGCAAGGNANTGCTGATTCTCCTCAGGACCTACCCCCACCA CCTCTCNTTGCTTCTAGACCTATAACTAGACTCAAGTCCCAGCA GGCCCCNAGGGGTNAGGTACAAAGTGTGACCCATGAGGAGGTAN NNTACACACCAAAAGAATTGCAAGATTTTNCCAATTTATATCGAC AGAAACCTGGGGAATATGTGTGGGAATGGATNCTAAGGGTGTTGG ATCANGGTGGAAGGAATATAACGTTGGATCGGGCCGAATTTATTG ATATGGGTNCACTAAGCAGAGATTCTGGATTCAATGTGTTAGCTCG AGNAGCTGGAAGTGGCTCTAACAGTTTGCTTGGTTGGTTGACTGA AACNTGGACTCAAAGGTGGCCTACANTNAATGAAGTTGAGATGCC AGAACTTCCTTGGTATANTGTAGAGGAAGGNATCCAAAGGCTTAG GGAGATNGGAATGTTGGAGTGGATTTATCATGTAAGACCTGCTCA CCTACACCCTCTAACTATGTCCCCGGGAGGGTCCAGGGACACTCC CTTCACCAAGGCNTTGAGAAATACATTNGTGAGGGGAGCACCAGC ATCCTTGAAGAGCTCTGTGGTGGCTNTTCTCTGTAGGCCAGGNAT GACGGTGGGAGATGCTGCCATTGAAATGGGCTCCCTGANTTCAAT GGGGATGATGGGATCCCGGGGTGGCAGAGGCCAAGTGGCGGCACT TAACCGCCAGAGACAAGGTGGGCGCGGTTACCGTAATGGGCAGCA GAGCCAAAGCGGTAATCAGAATGGTTTGACCCGCAGAGATCTTTG GCGNTGGCTAATTGATCATGGTGTCCCTAGGANTGAAATAGATGG GCAGCCTACTAAAGTCTTACTTGATTTGTATAAGCAGAAAAGCTC TAGGTCTGGTGAACAGAAGTCTGACTTGAGTCACCAACGGAGAGT CACGGCCCCTCANCCAGTTCCCAGACTTGAGCCAGTTCACAGCCA GACCCCTTGAATGAAGGGGAGGCCGGGTCCCCTTGAGGAAGGACC CTGCNACACTGCCAAAAATNTATACTGTAAATCTTCCTCCNAGCC TTCCCCAAAGGGACCTGCGGCCATTTACCAGGGTGACTGTGCACTG GGGAAAGGGAAATANCCAGACTTTTNAGGGATTACTGGACACTG GCTCTGAACTGACGCTAATTCCTGGAGACCCAAAACGCCACTGTG GTCCACCAGTCAGAGTAGGGGCTTATGGAGGTCAGGTGATNAATG GAGTTTTGGCTCGAGTCCGTCTCACAGTGGGCCCAGTGGGTCCNCG AACCCACCCTGTGGTTATTTCCCCAGTTCCNGAATGCATAGTTG GAATAGACATACTCAGCAACTGGCAGAATCCCCACATTGGTTCCCT GACCCGTGGAGTGAGGGCTATTATGGTAGGAAAGGCCAAGTGGA AGCCNCTGGAACTGCCTCTNCCTACCAAAATAGTAAACCAAAAGC AATACCGCATCCCTGGAGGAATTGCAGAGATTAGTGCCACCATCAAAGACTTGAAAGATGCAGGGGTGGTGATTCCTACCACATCCCCATAttorney Docket No. 60448-717.601SEQ SequencesIDNo TTAACTCGCCTGTTTGGCCTGTGCAGAAGACAGATGGATCTTGGA GAATGACAGTGGATTATCGTAAACTTAATCAGGTGGTGACTCCAA TTGCAGCTGCTGTTCCAGATGTGGTNTCTTTACTGGAGCAAATCA ATTCTATCTATNCCTCCCTACTTGAGCCCATGCTCTTAGGGTTAAATGACGAAGCCCTAACTCTAGGAATACGTCGAGGCTATATAGТGC CTTTCACCTGGCAGGGNCAGCAGTACACCTTCACTGTCTTGCCTCA GGGCTATGTCAACTCTCCNGCTCTCTGTCATAATNTAGTCCGCA GGGACCTTGATCGTCTTNNCATTCCACAGGACATCACGCTGGTCCA CTACATTGATGACATCATGCTGATTGGACCTGGTGAGCAGGAAG TAGCAAGTACTCTAGACGCCTTGGTAAGACACATGCGTGCCAGAG GGTGGGAGATAAATCCCACGAAAATTCAGGGGCCTGCCACCTCGG TGAAGTTTCTAGGGGTCCAGTGGTCTGGGGCATGTCGAGATATCCC TTCCAAGGTGAAGGACAAGTTGCTGCATCTNGCNCCTCCTACCA CTAAGAAAGAGGCACAATGCTTGGTGGGCCTCTTTGGATTTTGGA GGCAACATATACCNCATTTGGGCGTGCTGCTCCGACCCATTTACC GAGTAACCCGNAAGGCTGCCAGTTTTGAGTGGGGCCCAGAGCAAG AGAAGGCTCTGCAGCAGGTCCAGGCTGCNGTGCAAGCTGCTCTGC CACTTGGGCCNTATGACCCAGCAGATCCAATGGTGCTCGAAGTGT CTGTGGCAGATAGGGATGCTGTATGGAGCCTCTGGCAAGCCCCNA TAGGNGAATCACAGCGCAGACCCCTAGGATTTTGGAGCAAAGCCA TGCCATCTTCTGCAGATAACTATTCTCCTTTTGAGAAACAGCTCC TGGCTTGCTACTGGGCCCTGGTAGAGACTGAACGCCTGACCATGG GNCACCAAGTNACCATGCGACCTGAGCTGCCCATCATGAACTGGG TGTTATCTGACCCACCAAGCCATAAAGTTGGGCGTGCACAGCAGC ANTCCATCATCAAGTGGAAGTGGTATATACGAGATCGGGCTCGAG CAGGTCCNGAAGGCACAAGTAAGTTGCATGAGCAGGTGGCTCAGA CTCCCATGGCNCCTACTCCTGCTGCATTGCCTCCTCTCCCTCAAC CCGCACCTATGGCCTCATGGGGAGTTCCCTATGACCAGTTGACTGA GGAAGAAAAAACTCGGGCCTGGTTTACAGATGGTTCTGCACGAT ATGCTGGCACCANCCGAAAGTGGACGGCTGCAGCACTACAGCCCC ACTCAGGGGTGGCCCTGAAGGACAGTGGTGAAGGGAAATCCTCCC AGTGGGCAGAACTTCGAGCAGTGCACCTGGTTGTCCACTTTGCCTG GAAGGAGAGATGGCCAGAGGTACGGATCTACACTGATTCATGGG CAGTGGCTAACGGTTTGGCTGGATGGTCAGGGACTTGGAAGGAAC ANGATTGGAAGATTGGTGACAAGGAGGTCTGGGGAAGAGGTATGT GGATGGACCTCTCGGAATGGGCACAGAGTGTGAAGATATTTGTGT CCCATGTGAATGCTCACCAAAGGGCANCCNCNGCAGAGGAGGNTC TCAATAATCAGGTGGACAAGATGACCCGTTCTGTGGATGTCAGTC AGCCTCTTTCCCCAGCCACCCCNGTGCTTGCTCAATGGGCTCATG AACAAAGTGGCCATGGTGGCAGGGATGGAGGCTATGCATGGGCTC AGCAACATGGACTTCCNCTCACCAAGGCTGATCTGGCTACNGCCA CTGCTGAGTGCCCAACCTGCCAACAGCAGAGACCAACGCTGAGCC CCCGATATGGCACCATTCCCCGGGGGGACCAGCCAGCCACCTGGT GGCAGGTTGATTACATTGGACCNCTTCCATCATGGAAGGGGCAGC GATTTGTCCTCACTGGAATAGACACTTATTCTGGATATGGATTTG CCTTCCCTGCCCGCAATGCTTCTGCCAGNACCACCATCCGTGGACT TACAGAATGCCTTATTCACCGTCATGGTATTCCACACAGCATTG CTTCTGACCAAGGAACTCATTTTACAGCAAANGAAGTGCGGCAAT GGGCTCATGCCCATGGAATTCACTGGTCTTACCACGTNCCCCATC ACCCNGAAGCAGCTGGCCTGATAGAACGGTGGAATGGCCTNTTGA AGACTCAGTTACGGCGCCAGCTGGGNGACAACACCTTGNAGGGCT GGGGTNNTGTCCTNCAGGATGCGGTATATGCTCTGAATCAGCGAC CAATATATGGTGCTGTTTCTCCCATAGCCAGAATNCACGGGTCCGGGAATCAAGGGGTGGAAGTGGGAGTGGCTCCTCTCACTATTACNCAttorney Docket No. 60448-717.601SEQ SequencesIDNoCTAATGACCCACTNGCAAAATTTTTGCTTCCCGTCCCCGCAACTT TGGGCTCTGCTGGTTTAGAGGTCTTAGTTCCCAAGGGAGGAATGCT TCCACCAGGGGACACAACAATGGTTCCATTGAACTGGAAGCTGA GACTGCCACCTGGCCACTTTGGGCTCCTCATGCCACTGAACCAACA GGCAAAGAAGGGAGTTACTGTACTGGCTGGGGTGATTGATCCTG ATTATCAAGGGGAAATTGGGTTGCTGCTACACAATGGGGGCAAGG AGGANTATGTCTGGAATNCAGGAGATCCTCTGGGGCGCCTCTTAG TACTCCCATGTCCNGTGATAAAAGTTAATGGAAAACTACAGCAAC CCAATANAGGCAGGACCGCTAANGGCTCAGACCCTTCAGGAATGA AGGTTTGGGTCACCCCACCAGGCAAAGAACCACGACCAGCTGAGG TGCTNGCTGAGGGCAAAGGGAATATGGAATGGGTAGTGGAAGAA GGAAGTTATAAATACCAGCTACGACCNCGTGACCAGTTGCAGAAA CGAGGACTGTAGTAGTTATGNGTATTTCTTCCTTGCTTTGATATGA ATATATTTGTGATATATATATTAACNAATATCTTTNTTTTCTTTCCT CTCTCATTCCCCTACTATCTAACATAAGATGTGTTAATAGTAG TTAACCTTATATCTCAGTATTTAAGTTACAGGATATCAAAGGGGGA NTGTGACTCAGCTAGAAGAGNAATGAACATCACCCAGAGATGGA TAAAGTGACNTNTGGGACTTTGTATCCTCTTTTGGGGAGAGGGTTA GCGTGTTTTCGGTTGTACGAGGGATAGTTGCATCATGTTAGGCG GAAGCATGATTTTGCTATTGTCTTTATTTGGAAGTTAAATATGGTT NAAAGAGGTGTGTATGGATGCCGAGTTGACAAGGGGTGGAC18 GTTGGTACCAGGAGTGGTCCGAGAAAGCAGACGNTNCTAAGATGG Consensus GATTTTGGAGCTGGATCACCCGCCGNCCGGCTGGCAATGAGGACC sequence for CCATCACTGGTGGTAGGTGGAGCACGGATAGCCCCTGGCACGAGG transposable TAGCGGTGCAATTGTTAAAACTTTCACCGGTGGTGAACTGGGATG elements that GNATACCGGTGGAAAGAGAATGCACTGGCNGGTGCAATGTNTCAG belong to GCGTTTGAGAAATATGGGANGAATTAANTACATGNAAGGACAATG GAATTGGATGGCTGTTGCTAAGCNCGACTGACGCTCTGGAAAAAG HERV16 ACAATGAAAGGCTGAGAGCGATTAATCGNCAATTNAAAGCTAAGT subfamily GTGAAAGCCAGAGGGCCTCCTTGGCAGCATATAAAGAGACTCTCA TCTCCTGCAGCCGGAGGGCAGAGAAAGCTGAGGATCAGGCCCAGG ACTTAATCAGAGTAGCAGAGCTCCAGAGAAGGTTGAATTCTCAAC CNAGGCAGGTCTGCTATGCCAAGGTCAGGGCCCTGGTTGGGAAAG AATGGGACCCTGANACNTGGGATGGGGACATCTGGGTCGATGCNC CTGAAAATCTTGAATCCCCAGATTCCCCTGAACCCTCTGGGCCTG CAGAAGTGGCCCACTCCTCCCTGTTAAGGGCTAGCACTCNCTCCTT GCTTCGCGNGAAGACGATGCAGAGGCCTCTNCCTTNGCAAGACA ACATGCGCCCCCCTCAGGATCTGCCCCCACCTCCCCTCCTGGCCAC CAGACCAATAACTAGGGTTAAGTCACAGCATAACCCGGCCGGGG AAGTGCTGGGCCTGNTAAGGGAGGAAAGGGACTATACCCCAAAG GAGCTGCAGGACNCGNCTAGCCAGCATGTACCGGCAGGACCGGGA GAGTACGCATGGGACTGGATTCTGAGGGTGCTGGATCAAGGGGGN CGGAACATAAAGTTGGATAAGGGAGAGTTTATCGATNTGGGAGCA CTCTCCCGNGATACAGGATTTAACACCCTGGCAAGGACCCCGGGA GATGGTGCNAACACGCTGCTAGGATGGCTCCTGGAAGCNTGGAGA AAGCGATGGCCCACACTAAGTGAAGTAGAAATGCCAGAACTGCCG TGGCAGACGGTGGAAGAAGGGATCAAAAGGCTCAGAGAAGTGGG CATGCTAGAGTGGATATACTATGTAAGGCCGGAAAACCCACCAGA TGACTATGTTCCGCGGGAGGGCCCAGAGGACACNCCATTTACCAA AGCNATAAGGAATGCGCTGGTGAGAGGGGCACCAGCATCACTGAG AAGCTCAGTGGTGGCTNTCCTCTGCAGGCCAGGGCTGACGGTAGG AGANGCCGTTACAGAACTGGGCTCNCTGATAGCAATGGGGATGAT AGGACCCCGAAATAATAGAGGCCAGGTGGCGGCGCTTAACCGTCAGAAGCAAGGTGGGCGCAATTATCGTAATGNACGGCAAGGTCGGAGAttorney Docket No. 60448-717.601SEQ SequencesIDNo TGGCAGCCGGGGGGGCCTGACCCGCAGAGAGCTATGGAGATGGTT AATAGAACACGGCGTCCCTAGGGGCAAGATAGATGGGCAGCCAAC AGGAAGNCATGGACAGTTAATAGAACATGGCGTCCTAGGGGCAAG ATAGATGGGCAGCCAACAAGGGTGTATTGCTCAACTNAAACAANC AAAAGAAATCAAGGATGGATGANCAGGAGGCTGAGGGCAGTCGC CCCAATAAAAAGTCACGATCCCTTGCCCAGTTTCCGGACCTGAGCC AGTTTTCAGACCCGGAACCCATTGACTGAAGGAGAGGCCGGGTCC CCAGGAGGAAGGACCCTGCAACACCACGGCAAGTGTACACGGTAA TGATTCCCCCAGTCCTTCCCCAAAGGGACCTACGGCCATTTACTCT GGGTAACCGTACACTGGGGAAAGGGGAATACCCAGACATTTCGAG GACTGTTGGACACAGGGTCCGAGTTGACATTGATACCCGGAGACC CGAAGCGTCATCATGGCCCTCCCGTTAGAGTGGGGGCATATGGGG GCCAGGTAATAAATGGAGTCCTGGCCCAGGTCCGGCTCACAGTGG GTCCACTGGGTCCACGGACCCACAGTGGTCATTTCCCCGGTCCCCG AATGTATAATTGGAATGGACATACTTGGTAGTTGGCANAACCCCC ACATTGGTTCCTTGGCCTGTGGGGTAAGAGCTATCATAGTGGGGA AGGCCAAGTGGAAGCCTCTGAAACTGCCCTCACCTTCTCCGGNCA AGATAGTAAATCAAAAACAATATCGCATCCTCGGGGTGGAGAATG GCAGAGATTAGTGCCACCCTTAAAGACCTAAAGGATGCAGGAGNT GTGGTCCCCATCATATCTCCATTTAATTCACCAGTNCNGGCCCCTG CAAAAACCAGACGGATCCTGGANGACGACAGTGGACTACCGCAA ACTCAACCAAGTAGTANCCCAATTGCAGCTGCTGTGCCAGATGTG GTATCTTTGCTAGAGCAGATTAACACGGCCTCAGGTACGTGGTAT GCGGCCATTGATCTGGCGAATGCGTTCTTTTCCATCCCTATCAGAA AGGAGGATCAGAAGCAGTTCGCATTCACNTGGAACGGACAACAG TATACATTTACAGTCTTGCCCCAGGGCTNTGTTAACTCTCCTGCCCT CTGTCATAATATAGTCCGAAGGGACCTGGACCATCTGGACATT CCGCAGAACATCACATTGGTCCACTATATCGATGACATCATGCTAA TCGGACCGGAATGAGCAAGAAGTGGCAAGTACGTTGGAGGCCTT GGTAAGACACATGCGCTCCAGAGGGTGGGAGATAAACCCTACGAA GATTCAGGGGCCTGCCACATCAGTGAAGTTTTTAGGGGTCCAGTG GTCTGGGGCATGCCGGGACATCCCCCCAAAGTAAAGGACAAATTA TTGCATCTTGCACCTCCCACCACNAAGAAGGAAGCACAACGCCTG GTAGGCCTCTTCGGGTTCTGGAGGCAGCATATTCCACACTTGGGAA TACTGCTCCGACCCATNTACCGGGTGACGCGAAAGGCTGCCAGC TTTGAGTGGGGCCCAAGCAGGAAAGGGCTCTGTAGCTNACCGCAT ATCGTGTNCGAANCGCANANNCGGNCCTCCAAGTCATAAAGTNGG GCGGGCCCAGCAGCAGTCCATCATAAGGTGGAAATAGNATATCCG AGATTAAGCCCGAGNAGGACCAGAGGGCGCAGGTNAGNTNCATG AGCAGGTAGCCCAGACCCCCATGNCACCCACCACNGTTGCACCAG CGCCTCTCCTTCGGCTCGCACCTATGGCCATATNGAGGNNTGTGGT CCCGTATGACCAGCTGAAGGAAAGCTCGAGCTTGGTTTACAGGAT CAGCTCGGTATGTGGGCGCAAGCCAAAATANGTGGTGGCTGCACT ACAGCCCCATTCAGGGGTGGCCCTGAAAGGCAGCAGGGAGTGAAA ATATCTTCCCAGTGGGCAGAGCTGCGAGCAGTGCACCTGGTCATC CACTTTNCGTGGAAGGAGAAGTGGCCCGAGATGGTAATATATACG GATTNCTGGACAGTGGCCAATGGCCTGGTCGGCTGGTCAGGAGCT TGGAAGGAAAAGATTAGAGANAGGGAAGTCTGGGGTAGAGGCAT GTGGATAGACATATNGGAAGTGGCACGAAATACGAAGATTTTTGT ATCGNTNNTATGTTAACGCTCACANGAAAGCATCNACCATGAAAG AGNCACTGAACAACCAAGTAGACAAAGTGACTTCGACCACTGACG TTAGCCAGCCTTCGTCCCGGCCTCCTCAGANCTGGTNCAACGGACA TCTCAANAAAGTAGCCATGGTGGCAGAGATGGAGGCTACGCATGGGCCCAACAGCATGGACTCCTATNCACCAAGNCGATCTAGCTGCTGAttorney Docket No. 60448-717.601SEQ SequencesIDNoCCCCGTNTGAATGTCCAACCTGCAGCAACAGAGACCAATGCTCTA CCTCNAATACGGCACTATTTATGGAGACCACTTAGCGGCGAATTG ACTATATTGGACGCCTTCCATCCTGGAANGGNCAGNGATTCATTC TCACAGGAATANATACNTATTCCGGGTATGGGTTTGCCTTTCCTGC CTGCANAGCCTCATCNAGCATCTGAGGGNCTTAGGAGTGCCTGA TCCACAGGCATGGAATCCCACACAACATAGCATCTGANCAGGGCG CTCACTTCACAGCAAAGAAGNGGCACAAGTGGGTCCANAATAACG GGATCCACTTATCNTATCACGTACCGCACCATCCAGAAGNAGCTG ACCTNATAGAACGCTTCTGAAGGCACAGNTGAAGCACCAGTNGAG GCGAACTCTGAAAGAATTGGGTGCCATCCTCCAGGATGCAGTATA TACATTGAATCANAGGCCTATNCGTNGGGCNTTGNNTCTAATNGG GAGAATGGGATTAGGAATAAGAGGTGAAAGCAGGAGTGTGCCTA CTCCCCATCGTAGTGGCCCACAAGGATCACAGCAGTGGTTTGAAC ACGGATTGGACTACTGATATCCAGGAATCGCCGCACAAGAAGGNG AATCCACATTTGGCAGGAGTAATTGACCNTGATCANCAGGAGGGG TAGGGCTGCTNTCGCANAATGAGGAAGAAAGGAATATGTNTGGAA CCAGGTGATCCNCTTGGGTGCCTCCTGGTACTCCCTTGCCCCATTT AACTGTAAATGGACAATNCCACCGAAAAGAGCTCGGACCNCTCCG GAATGAAGGTTTGGNTCACATCGCCNGGTAAGCCACCAAGACCTG TCGAAGTGATAGCTGNGTGAGGGANATCTAGAATGGATAGTAGAA GAGGGAGACGATGAGTACCAGTTNCGGCCCCGAGACCAACTGCAG CAANNGGGGCTGTAGTTCGTCCCACTAACCTCCCTCTTCTAAGTTT CGCTTCAGAAAGAGAAGCTTAAAGGAATAATGGAGGAACTGCTC CNNGAACCTGNGTGGAGAAGTAGATCCGTCGAGTACAAAGGTGGAC19 TTTCTGGCGAGCCAGCCAGGAGTGGAGACGACAGGTTTGCTGTCT Consensus CCTTTGCCTGTGGGNCTGGAGCCCCGGGCCGGGGGAGACCTGTGA sequence for CCCCAGGCGCCGCCTGGGAGAACTTCAGCCCGGAGGGGAGATCGG transposable CTCTCCCGTGACCCGGCGCCCCTNCCCGGCAGCGCAACGGAACCT elements that AAGGGGCTACAGGACGATTCCAGGAACAGCGCGCTNCAGGACCGC belong to GGTAAGGTTTGGGGCCCAAGGCAGGACCCGTCCCATAAGGACGGA AGGGGAGCCTGATCACCTCCCGGGGTGTANCTAGTAGTCCGACCC HERV3 AGGAGCTGGGGGCGGCGAGAGTGGCTCGCCAATTCGGATGAAACT subfamily TACACCCCAACCAAGAANAGGAACTGGGAGTGGGGAAGTGTGTG AATGCGTGTGAAAGAGGCGGTTCCAGGAGGAGCCAATGCGGGGA GTGACGTGTGGGGCCGCAGGTCTCTTAGCGTGGACCGTACGCTCC GAGCGAAGTGTGGGGCCGACCGGGACTAGTGGCGAACGTCCTCCG NNNCCGCCGCATACGGCTNAGGGAGGCGCCCCACAACTCAGTGAT TGTGGTGGTCCGGGTTCGGGGNTNATACGAACCCTCCANTAAAGC TAAGCGGCGTCTGAAAACTCCCGTAAGGGAGACGGTCTAATCGGT CTGAAGCGAAAGTAAAAGAGTGAGTGTGTTGCGCCGTAACTGGGA GGAAATGGGAGGGAAGTCGTCAAAACCCACCCCATTGGAATGCAT GTTAAAGAACTTTAAGAAAGGTTNTGCAGGGGATTATGGAGTCAA GTTGACCCCCCAGAGGTTGAGAACTCTCTGTGAATTAGAATGGCCC TCTTTTGGTGTCGGATGGCCGGCCGAAGGAACTATAGATAGGGAA ACAATTGGCCGTGTATTTAAGGTGGTGACNGGGGTCGGAGGACAG CCAGGGCACCCAGACCAATTTCCTTATATTGACTCATGGCTAAATA TAGTNCAGACNCGACCAGCATGGNTNCAGCCCTGCCTAGCGGCTT ATTGCAAAACGCTCGTGGCTCGAGCCGAGCCNAAAGTGAAAGAAA AATCAGCTTCGCCGGCAGCCACGGAGNTAAAGGGAAAGCCACAG GAAGGCAAGAGAAGCCAGTTTTGCAGGAGCCGCCAGAGGAAACA GAAATTCCTCCTCCNTATGTCCCAGCCTACCCCCCTTTACCGAGGC CAACGGCCCCCGAGGAGCCAGATTCAGGNGNTAACACGCCCCAGGTCTCACCCCGAAGGGAAGGATCGGAGCCTCGGGAGGCCAAGGAGAttorney Docket No. 60448-717.601SEQ SequencesIDNo GGAAGTCAAGATAGTCAAGCGGGCCGCCTCNGATCTGGCCGCGCC CGAGCTATGCAAATGCCTCTCAGGGAGACGCGAGGACCCGTCTAT TATGATGANCAGGGCCANGTCCAAGGGGGGCAACGGACTTTCATC TACCAGCCCTTTTCAACCACTGATCTCCTAAACTGGAAACACCATA CTCCCTCCTACACGGAGAAGCCCCAGGCCCTCATAGATCTGATGCA GTCCATCTTTCTGACACACAATCCAACCTGGCCAGACTGCAAGCAG CTCCTCCTGACGCTGTTTAACACCGAGGAGCGCCGGAGGGTGAC CCAGGCAGCCCTCCGCTGGCTAGAAGCCAATGCGCCAGAAGGCGC ANTTAATGCCCAGGCATACGCTCAGGGCCAGTTCCCAGAAGCAGA CCCCNACTGGGACCCAGATGATGCAACCCAGCTTCAGCGTCTGCA GAGGTACCGAGAGGCACTCCTGCAAGGGCTAAGAGANGGCGGAA AAAAGGCAATCAATATAGGAAAGATCTCAGAGGTGCTTCAGGGAG CTGACGAGAGCCCNAGCCAGTTTTATGAGAGACTCTGTGAGGCAT TCCGGCTTTACACCCCGTTTGACCCTGAGGCTGCTGAAAATCAGCG CATGGTGAATACGGCATTTGTAGGGCAAGCCCAGGGTGACATCAG GCGGAAGCTGCAGAAGCTAGAAGGTTTCGCAGGCATGAATGCCAC CCAGCTTATAGAAGTGGCCACCAAGGTGTACGTTAACCGTGACCA GGAGGCAAAAAGGGAAGCTGATCGGAGGCTTAGGAAAAAGGCCG ATCTGCTGGCGGCAGCCCTCACGGAAAGGGAAGCTAGCATCGCGA GGGGACGCGGACGCGGACGCGGACGTGGAAGGGGCCAAGCTGGG CAGAGACCCGAGAGCCGGCCGAGGCTAGANAGGGATCAATGTGC GCGGTGCAAAAAGAAGGGACACTGGAAGGATGAGTGTCCAGAGG GCAATGAAGGAAATGGCCAAGGCCGTGAGACGAGAAGGCCGCCG GCCAAGGGCTGCCGCACCCTGGGGGAACCAGACACCGACCTGATC GGGCTGGCAGGGGCTGAAGGATATGAGGACTAGGACAGACCGGG CTCCNTCTCCTTAGGCCCCCAGGAGCCCATGGTCACATTAGAAGTN GGGGGCCAACTGATGGACTTTATGGTAGACACCGGGGCTGAACAC TCGGTAGTGACCCGGCCCATAGGGCCACTATCCAAGAACTATACA ACTATTGTNGGGGCTACNGGGGTCCCAGAGAAGAGGCCATTCTGC CGGCCAAGGAGGTGTGTCATAGGAGGACGAGAAGTCCAACATGA ATTCCTATACCTCCCAAATTGCCCAGTTCCCTTGCTGGGAAGAGAC CTACTCCAAAAACTGCAAGCACAGATTGCTTTTGGGCCGCAAGGG GATATGACTTTAAACCTGACTCACCCAAAGGCCATGGTGTTAACCC TTACCGTCCCGCAGGCTGAGGAATGGAGACTATACGCAAAANAGN CGCCAGAACCGGGANTAAATGAANTGTNTGGGCTACTTAGTAAAA TTCCTGGAGTATGGGCTGAAGATAACCCACCCGGGCTGGCTGTAA ATCAGGCACCGGTGGTAGTAGAGCTAAAACCGGGAGCAACTCCGG TTCGGGTTCGCCAGTACCCGCTTCCCCGAGAGGCCGTACGGGGCAT TCGCAAACACTTAGAGCGGCTCTNCAAACACGGAATCTTAGTCCG ATGCCAGTCACCCTGGAACACTCCACTCTTGCCAGTACGGAAGCC AGGGTCTGGTGAATATAGGCCGGTGCAGGACTTGCGTGCTGTAAA CCAGGCCACGGTGACCATCCACCCGGTGGTACCAAACCCGTATAC TTTAATGGGACTCATTCCGGCAAGTGCCGCCTGGTTTACNNGCCTA GACTTAAAGGATGCNTTCTTCTGTCTCCGCCTGGCACCAATTAGTC AGCCCATCTTTGCATTTCAATGGGACGATTNAGTCACAGGCACAG NGGNGCAGCTCACCTGGACTAGACTCCCACAAGGGTTCAAAAACT CTCCCACAATCTTTGGAGAAGCACTGGCCTCAGACCTCAAGGCCTA CACCCCGCCAAATGACAACTGCGCCTTGCTNCAGTACGTAGACGA CCTTCTTCTGGCAGCCCCAACCCGAGAGGACTGCTACCAAGGAAC CCAAGACCTCCTCCACCTCCTGTGGAAGGCAGGNTATAAAGTGTC CAGGAAGAAGGCTCAAATCTGCCNNGAAAGNGTCAAGTATTTAGG CTTCATAGTAAGCCAAGGGGAACGNCGGCTTGGCAGTGAACGAAA GCAGGCTGTTTGTGCACTTCCNACTCCAACCACCCGGCGTCAAATAAGAGAGTTCTTAGGGGCAGCAGGGTTCTGCCGCATCTGGATCCCAttorney Docket No. 60448-717.601SEQ SequencesIDNo AAATTTCTCGCTNATGGCTAAGCCATTATATGAAGCCACAAAGAG GGGGGAAAAGGAGCCCCTCCTCTGGGAGGCCGACCAGGAGAAGG CNTTTAAACAAATCAAAGAAGCCTTAACTCAGGCCCCAGCCTTAG GACTGCCAGATNTAACTAAGCCTTTCTTTCTGTATGTCCACGAGCG AAAGGGAATGGCTATAGGGGTCCTGACTCAAGTCATAGGATCATG GCATCGCCCGGTGGCGTACTTATCCAGGCAATTGGACTCCGTGGCG CTNGGATGGCCTCCTTGCCTTAAGGCACTAGCTGCCACCGCCCT ACTGGCACAAGAAGCTAACAAACTGACTCTAGGACAGCAACTGAC CATCCGGGTACGCCGCACTCGGTTATAACTTTAATGGACCAGAGA GGGCACCATTGGTTATCAAATCCGAGAATGACTCGGTACCAGGGG CTCCTATGCGAAAATCCCCGCATAACTTTAGAAACNGTGAACACC CTNAACCCGGCTACCTTGCTCCCGATCGAACCGGGAGNCCCCCTTC ATNACTGTGTGGANACGGTAGATGAGGTGTTCTCAAGCCGGAGA GATCTNACAGACCGGCCCCTCGGGGACCCGGACGTTGAATACTTC ACAGATGGAAGCAGTTTCGTACTAGAAGGGGTCCGCCGAGCCGGG TATGCAGTGGTGACNTTGGACTCAGTGGTAGAGGCNCAGCCTCTG CCTACCGGAACNTCNGCCCAGAAGGCAGAGCTAATAGCCCTGACA AGAGCTCTTTTGCTAGCAAAAGACAAAAAGGTCAATATTTACACN GATTCCAAATATGCTTTTGCCACNTTGCATGTTCATGGGGCTATA TACAAAGAAAGAGGACTCTTAACTGCGGAGGGAAAAAGAAATAA AGTACAAGGAAGAAATTCTACAGCTCTTAGATGCTGTATGGGCCC CAAAGAAGGTGGCTGTNATGCACTGCAGGGGGCACCAAAAGGCA GGAACACTAGAGGCCAAAGGAAACAGAAAGGCAGACAGGGAGGC AAAGCGGGCAGCAATGACTACTCCGCATTCTAAAGAGGAAGCCCT AGCTATGCCTCTCCTCCCGGAGNCTCCCCTCCCGGAGATCCCAAGT TACNCTCCAAATGAAAGGGCCTGGTTTGCCCAAGAANCTGGAAAN TACATTGAAGGAGGATGGTGGAAATTCTCCGATGGGAGGCTAGCC ATNCCTGAAATGGTGGCCCCCAAATTTGTAAAACAATTCCACCAA GGAACTCACATGGGAAAAACGGCACTAGAAACGCTACTAGGACGC CATTTCTATGTGCCACGGCTCACTGCCATCACTCGAGCCGTTTGCG AACAATGTCTAACTTGTGCCCAGAACAACCCACGACAAGGGCCCA CTCGGCCCCCCGGGAATTCAGGAAATAGGAGCCACGCCCTGTGAA AACCTGCTTATGGACTTCACCGAACTGCCCCGAGCNGGGGGCTAT CGGTACATGCTGGTGCTCGTTTGCACCTTTTCAGGATGGGTCGAGG CTTTCCCCACCAGGACAGAGAAAGCACGAGAAGTGACTAAAGTAC TGTTAAGAGACATTATCCCCAGATTTGGACTGCCTCTAACTCTAGG GTCAGACAATGGACCGGCATTTGTAGCTGAAATAGTTCAGGANC TAACACGGCTGTTAAAAATAAAATGGAAGTTACACACAGCCTACC GGCCGCAGAGCTCAGGAAAAGTGGAGCGCATGAACCGGACACTC AAGCAGCTACTGAAGAAATATTGCCAGGAAACTCATCTGAGATGG GATCAGGTCTTGCCCATGGTCCTCCTCCGAGTCAGGTGCACCCCCA CCAAACAAACTGGGTATTCGCCCTATGAGATTTTGTTCGGCCGGCC ACCCCCAATCATAGGTCAAATTAAAGGTGATCTCCGNGAACTAG GGGAATTAACCTTAAGAAGGCAAATGCAGGCTTTAGGGATAGCCA TGCAAAANGTCCATGGCTGGGTACGGGAAAGAATGCCTATAAGCC TGACAGACCCAGCACACCCCTTTAAACCTGGGGACTCTGTTTAGGT TAAGAAATGGAATCCAACCACTCTAGGACCCATATGGGATGGGC CCCATACTGTAATCTTGTCCACTCCCACTGCTGTTAAAGTTGCAGG NATCGTGCCTTGGATCCACCACAGTCGGCTGAAACCGGCAGCCC AGGACAAGTGGACCAGCCAGCAGGACCCAGACCATCCGACCCGG CTGATCCTGCGACGAGACCGAGTTGCCGCTGAGAGACGACGACAG CCCTGCTCTGGTCACTCCGGAAGCTGACCAGTCTACGCACGGCTGA AGCTTGAGGAGACAACAGCCCTGCTCTAGTCACCCCGGAAGCTGACTAGTCTACGCACGGCCGAAGCTTGAGTANTCATCAAGNAAGTAAAttorney Docket No. 60448-717.601SEQ SequencesIDNoATGTGGTTAGAAATCTTAAGNCCAGTAGTTTTCCTTGTAATACTA ATTGTTTTACTATTGTTCTGTCGCTTTGCTCAACCTCCTCCCCCGGG TAAAGACCTCTTCTGTCCNTGCTGGGTATAAANATGCTACTCT TTACTTNNTTGTTCCGGCGNNCGNNGCTACNNNTTTCCTCCTNATT ATGNCACTCCCCTTANCCGTGTCAGAAGAAGAGCCCATAGAAGG GTGCCCCCACTGCACNCACACTACNTGGTCAGGGAGCACNATAAC TAGAACCCTGTTGTACCATACTTATTATGAGTGTACAGGGACCCG CCTAGGAACTTGTACTCACAACCAGACGACCTACTCAGTCTGTGAC CCAGGAAATGGCCAGCCTTATATATGTTATGACCCCAAGTCCTT ACCTGGGACCTGGTTTGAAATTCATGTGGGTCAAAAGAAGGAAAC CTTCTAAACCAAACCAAGGTCTCTCCCTCCCACGGGGGGGCTATN TCCTTGTACTTTGATGTTTGCCAGNTAACATCCATGGGCTCAACCT TTCCCGTAATCTCTAGTTCCGNAGAGTACTATAGNAGCTGCCAC AAAAATATATGCGCACCCCCTGCTTGCTCCGCCAGGTCCCCAGAA ACAGCTTGCTGGGACTGCACAATCGGTCCNCTGACCCGCAATCAC CGGGGCCAGTCATGCTTACCAAAATGCCAGCAAAACCAGATTGTA AGACAAGCACTTGCAATCCTGTAAATCTCACCATCTTAAAGCCGG ATCTGCCCATATGGACTACAGGTTTANNNGCACCCCGGGANTACA AGTCAGCGGTCAGAAAACNGACCCAGAAGCCTATTTATATATTAT CAAGAAANCTCGGACCCGTCCGCCCGANAATTCCAGTCTTTAAGT CATTCTNTGAGCATATNAACCAGAAGTTGCCNGAGCCCCCTCCTT TGCCAGAAACCTATTCGNCGCGNNNCGTTTGCNTGCTCAGCTGGCT GAAAACATNGCCGGCAGCCTAGGCGTCTCCTCATGTTATGTTTG TGGAGGGACCAACATGGGAGACCAATGGCCNTGGGAAGCAAAAG AGTTAATGCCCCAAGATAACTTCACTCTACTGNCTCTTCCCCCGAA CCGACGCCCACAAGTTCGAGCGTCTGGCTCTTAAAAACCTCTATTA TCGGGAGATNCTGCGTTGCTCGCTGGGGAAAAGCCTTTACAGAC CCAGTAGGAGAATTAACCTGCCTAGGACAGCAATATTACAATGAA ACACTAGGAAAAACTTTATGGCGGGGCAAAAATAATTCCAAATCG CCCCANCCAAGCCCATTCTCCCGTTTCCCTTCTTTAAACCACTCTTG GTACCAACTTGAAGCTCCAAATACCTGGCAGGCGCCCTCTGGC CTCTACTGGATCTGTGGGCCACGGGCATATCGGCAGTTGCCGGCTA AATGGACAGGGGCCTGTGTACTNGGAACAATTAGGCCGTCTTTC TTCCTAATCCCNCTGNAACAGGGAGAAGCTTTAGGGTACCCCGTCT ATGATGAAACTAAAAGGAGAAACAAAAAGAGACATAACCATAGG AAATTGGAAAGACAATNAATGGCCCCCTGAAAGAATAATCCAATA CTATGGGCCAGCCACCTGGGCAGAAGATGGGNCGTGGGGATACCG CACCCCTATTTACATGCTCAACCGCATCATAAGGTTGCAGGCAGTG CTTGAAATCATCACTAATGANACNGCAAANGCCTTAGATCTGCT GGCCCAGCAAGCCACAAAAATGAGGAACGCTATCTATCAAAATAG ACTGGCTTTAGACTACCTCCTAGCCCAGGAAGGAGGAGTATGTGG AAAGTTCAATCTAACTAATTGCTGCCTAGAAATCGATGACAACGG AAAGGCCATTANGGANATAACTGCAAGAATNCGAAAATTAGCCCA TGTTCCAGTCCAGACTTGGAAAGGGTGGTCTCCAGATTCCCTCTTC GGAGGCTGGTTTTCATCCTTCGGAGGATTCAAGACCTTAATAGG AGTAGTTCTGGCCATACTAGGAGNCTGCCTAATACTCCCTTGTCTC TTACCCCTCCTTGTTAGAAGCATTCAATCAGCCATAGAGGCNNT TGTAGCCAGGCAAACTACCACTCAGCTAATGGCTCTAACTAAATAT CAACCTTTGCCAAANGAAGAAAACTGCCTCTTCATGAAGAATTA AGTAATAGTGATGCTTTCTATTAAACTTCATTTATAAAAAGCATCA AAGGGGGGAA20 AGTGGCGTCCGAACACAGGGACTTCGAGGACGTGAACGAAGAAG Consensus GTCTGCTGGAGCAGAGGAACTGAAATTGACAAGGCGAACGGGGA sequence for CCCCGGGACGAGTCTGCCGGCAGCGGATATAAGGTCAGTGCCCTAtransposableAttorney Docket No. 60448-717.601SEQ SequencesIDNoAAGAGGTACTGGGAGCAATATAAGGTCAGTGCCCTAAAGAGGTAC elements that TGGGAACGGGAAGTTTTCTGAATCAGNGGTAACATGGGGCAGAAT belong to TTGTCTATTGAAGAAAAACATTATCGTGCAGTTGCTTAAAGTTCTG HERVK3 TTGAGACAGTCTGGNGCTCAGGTTAGTTCNCAGACACTAACTAAG subfamily ATGCCGCAGGAGGTTATTACGCATAACCCATGGTTTCCACAGGCA GGCACTCTTGATGTGGAAAATTGGGACAGAGCAGGAGAAGGATTA AAACGGGCTCATCAAAAAGGTCTTAAAGTTGATTCTTCTGTTTTCT CCACTTGGAGTTTAGTTCGTACTGTNCTTCTGCCATTATCTCCTTNT TATTCTGCNGGACAGCAGGAGTCATGTTCTGAGTCTAAAAATC TGAAAGAATCTGTTGTCCCACCCACAGCTCCAATTGAAAATAAAA AACAGGAGAGGGAGGATAAAAATTGGCCTATACCGCCTCCTCCAG TTGCAGAAACATCTGTACCGCCTCCTTCGGTAGCAGAAATAGAGA CCCCAATACAAAGAATTTTACGCTCTGCTGCCATAGCTGGAGAGC CCTTAGGACCTNTGCGCTTTTCCTATTTCCGTAAGGCCTGATCCAA ATAATCCACAGCAGNTTATTCATGAACACACCCCACTAGAGTTT AAGTTGTTGAAGGAATTAAAAGCTAAGTGTGGTNAATAATGGCGT ACAGAGCCCATTCACTTTAGGATTGCTAGAATCTGTGTTTGGTGC TATGCGTCTTCTACCCTTTGATGTAAAACACTTGGCNCGAACTTGC TTGTCTGCTAGTGCATATCTGACATGGAATTTAAATTGGCAAGA AATGTGTGCAGACCAGGCTAGACAGAACCGTGCTGCTGGACACGG AGACATTACAGAGGATATGCTGTTAGGTAATGGCCCTTNATTCAG ACCTGGAACGTCAAATGGCACTCCCAGACGCTGCTTATCAGCAGT GTGCACAGGCCGCTAAACGCGCCTGGGCCACAATTCCTGAAGAGG GAGTCCCAGTACAATCCTTTTTACATATCATGCAAGGGTCGCAGGA ACCCTATGCGCAATTTCTTGCAAGATTACAAGAGGCAGTGAAGC GTCAGATTCCTCATACCGCTGCCGCAGAAATGCTAACCTTAACTCT AGCTTTTGAGAATGCAAACGCGGATTGTAAACGTGCACTGGCAC CTGTGAGGTGTAAAAAAACTTGGGAAATTTTCTCAGAGCTTGTCAG GATGTAGGAACTGAGCTTCATCGCTCTGCAATGTTAGCNCAAGC AATGGCTAATTTAGCAGTTGACAAATCTAAAAGGAGCCAAGGGTC AAACCCTAAAATGGGAAAATGTTATAATTGTGGAAAAACTGGACA TTTTAAAAAGGAATGCCGCCAGATCTCAGGACAGAAAGGACCTTA CAATGCAGTNCCCCCCACCCCCGCGNNCCAGCGGAAAAAAACGCC AGGACTTTGTCCTCGCTGTAACAAAGGAAATCACTGGGCTAATCA GTGCCGCTCAAAATTTCATCAGAATGGCACCCCCCTGTCGGGAAA CGAGANGGGGGCCTGGACCCGGGCCCCTCAAACAATGAGGGCATT CCCAGTCCAGACCACAACCCCGTTTCAGGGATGGGTTCCCGGAGG NACATTGATTCCCTCACCCCAGGAACACCAGGAAGTGCAGGATTA GATCTCCCCGCCAGAGAAAGAATTACGTTAGTTGGNGGAGACAAA CCCACCAAAGTTCCCACTGGCATTTGGGGACCTTTACCAGCAGGAT ACATGGGACTAATTTTAGGCAAAAGCCGCCTTAACTTGCAAGGC ATTACTGTAGTCCCAGGAGTNGTTGACTCCGATTATGAAGGAGAA ATTCAAGTAGTTTTAATGTCACAAGATCTTTGGGTTTTTGAACCG GGAGAATATATTGCTCAATTATTGCTTATTCCCTGCAAATTACACC CTTCTCCACGAAAGGAGAAACGAGGAAATAAAGGGTTTGGGAGC ACAACTACATGGGAAATCTATCTATCCNCAACCCATAGCCTCTAAT AGACCCACCTGTGTAGTACAAATTAAAGGAAAGAAATTTTATGG GCTTATGGATACGGGAGCTGATGTGTCAGTAATATCTAGNAACGA CTGGCCCCCATCCTGGCCCCTGCGATTAACTTCTACATCCCTAGT GGGAGTAGGAACAGCTCAAAGTGTTCAACAGAGTGCTGAGATTTT ACCTTGTCTTGGTCCGGATGGACAGTCATGTACTTTTCAGCCTTA TGTTGCAAATATAGCTATCAATTTATGGGGTCGAGACTTACTTACA GCATGGGATATGAGACTTACAAATGAAAACTTTGATAACCCAGGATTTAAAATGTTGAAGGACATGGGATATCAGAGTGGAAAAGGTTTAttorney Docket No. 60448-717.601SEQ SequencesIDNo AGGGAAATTCCTACAAGGAAACCCTAACCCGATATCAGTAACTGG AAAAACAGATAGAAAAGGGCTAGGACGTCAGGATTTCTGACGGG GGTCATTGATATTTCTCCTCCGCCCACTGCCTTACCATTAGAATGG CTNAGTGACAAACCTGTGTGGGTGGATCAATGGCCCCTANCACAG GAGAAGCTAGNTCAACTTCATCNGCTAGTAAAAGAGCAATTGGAT GCAGGACATATAGAGAAGAGTTNCAGCCCCTGGAATTCACCGGTG TTTGTTATTCCAAAAAAGTCCGGAAGATGGTGACTGCTGCATGAT TTGAGAGCTATTAATGCACAAATTAAACCGATGGGTGCATTACAG CAAGGTCTGCCATCCCCAGCGGCCATTCCAAGAGACTGGCCTCTC GTAGTAATAGATCTTAAGGATTGTTTCTTTACTATACCNTTACACG AGAAGGATAAGCCTCGATTTGCCTTCTCTGTGCCTTCTATTAAT CAAAGAGAACCTGTTTCTCGTTATCAATGGAAAGTTTTACCCCAAG GCATGCTTAACAGTCCTACGCTATGTCAGCATTTTGTAGGACGG GCATTAAAGGAGCCTCGGAATATGTTTCCCACTGCTTACATCATTC ATTNTATGGATGATATTCTTTTGGCCGCTCCTACAGATCAAATC TTACATCAGTTATTCAGAGAAACAAAGCGGGCTTTGACTAAATGG AATCTCAAAATNGCTCCAGAGAAGGTGCAAACAACTTCCCCATAC CANTACTTAGGAACTATTGTTACGGAGAGAAGTGTACGGCCTCAG AAAGTAGTTCTCCGTAAAGACAGGTTACAGACTTTAAATGATTTT CAACAATTATTAGGGGATATTAATTGGCTGCGCCCGATGCTAGGTA TTGCTACCTATCAACTTACACATCTTTACCAAACCCTGCAAGGA GATTCTTCNTTAAATTCCCCGCGGCAACTNACTAAAGAGGCAGAA GCCGAGTTACGGCTTGTAGAGCAGATGCTTCAGCAGAGACATGCC TCNCGGCTACAGCCGCAAAAACCTTTGCTTTTGTTTATTCTTCCTAC CCCCCACTCTCCAACAGGACTTTTGGGCCAGTTCATAGACAAG TCTGTAACAGTAATAGAATGGCTCTTTCTACCTAATCAGTCAAAAC CTTGCAAGTTTATCTTTCTTTAATTACACAAATTGTGACTATGG GCAGGCATAGGTCAAAAATGCTTACGGGATATGATCCNGACAAAA TTATTGTTCCCTTAGACTCCCAGCAACAGGCCGCAGCNTGGGAAA TGTCGACTGCNTGGCAAATCGCTTTCGCAGACTTCGTGGGAATAAT AGATAACCACTATCCCTCAGACAAAATTTTGCAGTTTTATAAAG TCCATTCTTTCATTCTTCCTGTGATTACTCATCACAAGCCTATTCCA GGTGGACAGACTTATTTTACTGATGGCTCTTCCAAAGGTCGTG CAGCTATCTATGGACCTAAACATACTCAAACAATAATGACCTCTGG GGTTTCAGCTCAACGCTCAGAGCTAATTGCAGTCATTCAGGTTT TACAGCTCACAGCTTCAGATCCTATCAACATTGTCTGTGATTCAGC TTATGTTGTAAATGTAGCCAGTCGCATAGAAACTGCTACAATTA AAAGTACACTAGACCCAGAACTGCTTAATTTGTTTCTAAGACTTCA NACAGCTATTCGCTCTCGTGCAGCTCCTTTTCATATTTCTCATA TTCGCTCTCACACACAACTTCCTGGACCACTATCTCTAGGTAATGA TAGAGCAGATAAACTGATTGGTTCTGTGTTTCAGCAAGCTCAAG CNTCTCNATGCGCTACTGCACCAAAACACCTCCGCCCTTACTCGCA TGTTTCATCTGCCTCGCAGCCAAGCTAGGGCTATNGTACAAGCC TGTCCTACTTGCCAGCATGTCCCTGGNGCCGCACCTGTAGAAGGNT GTAACCCACGAGGTTTGGCTCCAAATGAAATCTGGCAAATGGAT GTTACACACATAGCAGCCTTTGGCAAGCTTAGCTATGTTCTGTGAN CTATAGACACTTATTCTCATATGCTGCATGCTACATGCCAAACA GGTGAGACAGCTGGTCATGTACGGCGACATTGTCTGTCATCATTTG CTCATATGGGGATACCTAAACAATTAAAAACTGACAATGGACCC GCTTATACTAGTCATGCTTTTCAAAATTTCTTACAGCTTTGGGCTAT AACCCATAAAACAGGAATTCCTTATAATCCTAGAGGACAAGGC ATTATAGAGCGGGCACATCAAACATTACAACGCATGTTGAAAAAA CAAAAAGGGNGGTATAGGAGGCCAACTACCACCTCAATCAAAACTACATTTAGCCTTATTTACTTTAAATTTTTTNGACTCCTGGTACGGATAttorney Docket No. 60448-717.601SEQ SequencesIDNoGGTAAGACTCCAGCAGAAAGACATTGGCAAGTGTTAGAGGAAA AGAGGAAAGTTTATCCGAAAGTGTTATGGAAATCCCCGGAAGAAG NGACAATGGAAAGGTCCGGTGGATTTACTGACGTGGGGANGAGGG TATGCTTGTGTTTTTACAGGAGATGGACAAACCGTGTGGGTGCCCT CAAGGTGCGTGCGACCATGGAACGGGAGACTGGAGGAACCCAGG GTGGCCAACCATGGGCCCGGTCCCTCCGGTACGAGCCATGAGCCA GCTGAGCCTGAGTGCAAAGACGGAGAGAAGGCCGACCGGAGTCA CGACGACATCAACCCCCATAACCTGGGGACAACTCAAGAAAACCA CGCAGGAAGCTGAGAAACTACTGGAGCGTCAGGGNCAGGCAAAA ACCCCTGATTCCATGTTCTTGGCCATGTTAGCCATAATGTCCTGTG CGGTATGTTTTCCCTGTGCAGAGGCAAAAACATATTGGGCATATGT TCCCAATCCCCCAGCAGTACGACCTGTACTTTGGAGTGACACTCCT CCTGAGATTTATCATGATCAGGGAGCGTGGGCTCCAGGACCCCT AACTCCCCTGACANTAGAACAGTTAGACTCTCAGAACAATGTCAT CAATTATACCGCTCCACTGGAAGGACTCCCTTTGTGTATCACCAC AAAGACGTCGCTCAGCCGTAGCTGTCTTACAATTCAAGCTCAAGC ATGGTTGAGTCACTATGGAAAAGTCATGTACTTATTAGGTCTTGG TTCTATTAATGTAACTGGTGTGCTAACCAACCATTCCCGGCCCAAT CGCCCTAATTGTGCTGACTATACGGAATGGATTCCCTTCAATAG TTCCTACCCCCCCTCNCGTGGACCCAGTGTCTTGGCCCACTGGCTA GAAAACAATCTATGTTAACTGGAGACATTGTGGATTGGGGACCT AAAGGTCAATTAGATGGAAAAGATGAAAATCAGAAATCATGGCAC AAACTTCGCTGGCATTGGTGGCAAGCTTTTAATGCTTCTTCTTTA TACNACACCGGGATCCAATCCCAGTCTGCCGCCCAGATTGCTTGGC ATGGAGCAGGCTTTAGCCCGCCTCTTCCTCAGTGGCATTATCTA GGGAGGAAAGGACCAATTCAAGAGACGATATGGAAGGCAGCACT CCCATTTACGAATGGAGCATCTGGGTTNGGGATACTATCCAATAAT AGCAATAGTAAGCGACACAGTCTTAATGTTACATTTGTAAAGAAT ATCACCACTCAATTTACGGTTTGTGTTTTTAATCCTTATGTCTTT TTGGCAGCTAAGAAGGACCAGCTCCAGGTAAACAATACCCAATTG ACCTGTAAATCTTGCCAGTTATATCACTGCATTAATCATAGCACA TTGCAAACACATAATATCTCTACTTTGATGATTTTGGGTCGCATCC CTGGGCTATGGATTCCTGTTAATCTGTCCGAGCCTTGGGCTGCC ACACCTGCTTTGCATTTTGTGAAACTTCTTCTAACTCAGCTTACTCA TCGTGTCCGTAGAGCCTTAGGCATGATAATTTTTGCTATTGTT TCCTTGGTCACACTAATAACTTCTGTTGTGATGTCCTCTGTAGCTTT GCATAGTTCTGTTCAAACAGCTCAGTACGTGGAGAACTGGACG CGCACAGCCGACCAAGCGTGGCTACTTCAGAATAAAATTAACACT GAGTTACAAACTGAAGTGGCAATGTTGAAATCCACGGTTCTATGG TTAGGGGAACAAGTACAAAGCTTGCAGTTGCAGCAGCAATTGCGT TGTCATTTTAATCACACTCATATTTGTGTAACCAACTTAGAATAT AACCAAAGTGAGTATCCGTGGGACCTTGTGAAAGCCCATTTGCAG GGAGCTTTCACATCCAACATCACCTTTGATATTGGTGAATTACAA AACAAAATTCTTGATTTAAATAGGCAAACTCAAGAGTTTCAGCCTT CTTTAGAAGACTGGACCGAATTCCAGCAAGGCCTGGAGAGCCTC AACCCTTGGACCTATCTAAGGCACCACATTAACATCTTATATGTAG TTCTTGGAATAATGTTGTTTTGTCTCTGTCTTCTGTTCATAGTC TGTAAAATCGGATGGACCGCCAATCGGAGAATGAGAGCTGCCCAG CCTGGCCTTACATTCTTTCAATTAATNCATAAACAGAAAGGGGGA TA21 GATTTTGGTACCAGGAGTGGTTCTAGAGGAACAGAATATTAAGGA Consensus TGGAGTTCTTTCGTTGGTTTTGGGGTTTCTGGAGTTGGCTGCTTA sequence for ATATGATTAGACCCAAAAATGCTAAGGACTCTACTTCTAATAGTAT transposable GGAGAACACTGATAGTCCTTGGCGTGAACTGTTTAGAGAGTTATelements thatAttorney Docket No. 60448-717.601SEQ SequencesIDNoGCAAAATAAATGCATTTGACACTCCTGATTCACCGCTCGTGAGAG belong to GCAAGGAGTTTAGTGACTCTATACATAATACCTTTGACCATATGT HERVL GGAGAACCAAGGAACATAATGAAGCTGGTTGGTTGCTCCTAAGTT subfamily CAGTGGACAAAGTGATGAAAGAAAATGATGAACTCAGGGATTCTA TCTCCCGGCTTCAGAAGCAGATACTGAGCCTCAAATCTGCTAAGAT TGCCCTGAGTGAGAGTCTTATCTCCTGTAGAGAAAGAGCTGAAA TTGTGGAAAAACAGACACAAGCTCTTATCATGCGAGTGGCTGACC TGCAACGAAAGGTGCATGCACAGCCTCGCCAGGTGTCTACTGTTA AAGTGAGGGCATTGATTGGAAAAGAATGGGACCCTGCAACTTGGA ATGGGGACGTGTGGGAGGACCCTGATGAAGCTGGGGACACTGAGT TTGTAAACTCTGATGAACCTTTTTTGCCAGAAGAAACAGCTTCCCC ATCCCCAGTAGTGGCAACATCCCCTCCCCGACCCATGCTGCCAT CAGCCTTTCCACCTTTGTCTGAGGAGATAAACCCTGCGCTGCCTGA GGCAACAGTGATGGCCTCCCCTGAGGCAGTTGCCAGGCAAGATA ATGTTGATTCTCCTCAGGAGCCACCCCCAACACCCCTGTTTGCTTC TAGACCTATAACTAGACTAAAGTCCCGGCGGGCCCCTAGAGGTG AGGTTGAGAGTGTGACCCATGAGGAGGTGCGCTACACTCGAAAAG AACTGCTTGAGTTTTCTAATTTATATAAACAGAAATCTGGAGAAC AGGCATGGGAATGGATATTAAGGGTGTGGGATAATGGTGGAAGGA ACATAGAGTTGGATCAGGCTGAATTTATTGATTTGGGCCCACTAA GTAGGGACTCTGCATTTAATGTTGCAGCTCGGGGAGTTAAAAAAG GTTCTAATAGTTTATTTGCTTGGTTAGCTGAAATATGGATTAAAA GATGGCCCACTGTGAGCGAGCTGGAAATGCCTGATCTCCCTTGGTT TAATGTAGAGGAAGGGATCCAAAGGCTTAGGGAGATTGGGATGG TGGAGTGGATTAGTCACTTTAGACCTACTCATCCCAGCTGGGAGGG TCCAGAAGATATACCCTTGACCAATGCCTTGCGAAATAGATTTG TGAGGGCAGCACCTGCATCTTTGAAGAGCCCTGTAATTGCTCTTCT CTGTATGTCAGATCTAACAGTGGGAACCGCAGTCACTCAACTAC AAAATTTAAATACAATGGGAATAATTGGATCCCGAGGTGGCAGGG GCCAAGTGGCGGCACTCAACCGTCAAAGGCAAGGTGGGCGTAGCT ACCGTAATGGACAGCAGAGGCAAAGCGGCAATCAGAATAGTCTGA CTCGTGTAGAGCTCTGGCATTGGCTAATTAATCACGGTGTTCCTA GAAGTGAAATTGATAGGAAGCCTACTGCATTCCTACTTAATTTATA TAAGCAGAAAACTTCTAGGTCGAATGGACAAAAGACTAATTTGA ATTATAAAAACAGAGAATCACGGCCCCTCAATCAATTTCCAGACTT GAGCCAGTTTACAGACCCAGAACCCCTTGAATGAAGGGGAGGCC GGGTCCCCTTGAGGAAGGACCCCACTACACTACCGACAATTTATG CNGTGAATCTTTCTCCCATCCTTCCCCAAGGAGACCTCCGGCCTT TTACCAGGGTAACTGTGCACTGGGGAAAGGGAAATGATCAGACAT TTCGGGGACTACTGGACACTGGCTCTGAGCTGACGTTGATTCCAG GGGACCCAAAACGTCATTGTGGTCCTCCAGTTAAAGTAGGGGCTT ATGGAGGTCAGGTAATTAATGGAGTTTTAGCTCAGGTCCGACTTA CAGTGGGTCCAGTGGGTCCCCGGACTCATCCTGTGGTCATTTCCCC AGTGCCAGAATGCATAATTGGCATAGACATACTTAGCAGCTGGC AGAACCCCCACATTGGCTCCCTGACTGGTAGGGTGAGGGCTATTAT GGTGGGAAAGGCCAAATGGAAGCCATTAGAGCTGCCTCTACCTA GAAAAATAGTAAATCAAAAACAATATCGCATCCCTGGAGGGATTG CGGAGATTAGTGCCACCATCAAGGACTTGAAAGACGCAGGGGTGG TGATTCCCACCACATCCCCGTTCAACTCTCCCATTTGGCCTGTGCA GAAGACAGATGGATCTTGGAGAATGACAGTGGATTATCGTAAGC TTAACCAAGTGGTGACTCCAATTGCAGCTGCTGTACCAGATGTGGT TTCATTGCTTGAGCAAATTAACACATCTCCTGGTACCTGGTATG CAGCCATTGACTTGGCAAATGCCTTTTTCTCCATTCCTGTCCATAAGGCCCACCAGAAGCAATTTGCCTTCAGCTGGCAAGGCCAGCAATAttorney Docket No. 60448-717.601SEQ SequencesIDNo ATACCTTTACTGTCCTACCTCAGGGGTATATCAACTCTCCGGCTTT GTGTCATAATCTTATTCGGAGAGACCTTGATCGCTTTTCGCTTC CGCAAGATATCACACTGGTCCATTACATTGATGACATTATGCTGAT TGGATCCAGTGAGCAAGAAGTAGCAAACACACTGGACTTATTGG TGAGACATTTGCGTGCCAGAGGATGGGAAATAAATCCGACTAAAA TTCAGGGACCTTCTACCTCAGTAAAATTTCTAGGGGTCCAGTGGT GTGGGGCCTGTCGAGATATTCCTTCTAAGGTGAAGGATAAGTTGCT GCATTTGGCCCCTCCTACAACCAAGAAAGAGGCACAACGCCTAG TGGGCCTATTTGGATTTTGGAGGCAACACATTCCTCATTTGGGTGT GTTACTCCGGCCCATTTATCGAGTGACCCGAAAGGCTGCCAGTT TTGAGTGGGGTCCAGAACAGGAGAAGGCTCTGCAACAGGTCCAGG CTGCTGTGCAAGCTGCTCTGCCACTTGGGCCATATGACCCAGCAG ATCCAATGGTGCTTGAGGTGTCAGTGGCAGATAGGGATGCTGTTTG GAGCCTTTGGCAGGCCCCCATAGGTGAATCACAGCGGAGGCCTC TAGGATTTTGGAGCAAGGCCCTGCCATCTTCTGCAGATAACTACTC TCCTTTTGAGAGACAGCTCTTGGCCTGTTACTGGGCTTTGGTGG AAACTGAACGTTTGACTATGGGTCATCAAGTCACCATGCGACCTG AACTGCCTATCATGAACTGGGTGCTTTCTGACCCATCTAGCCATA AAGTGGGTCGTGCACAGCAGCATTCCATCATCAAATGGAAGTGGT ATATACGTGATCGGGCTCGAGCAGGTCCTGAAGGCACAAGTAAGT TACATGAGGAAGTGGCTCAAATGCCCATGGTCTCCACTCCTGCCAC CCTGCCTTCTCTCCCCCAGCCTGCACCGATGGCCTCATGGGGAG TTCCCTATGATCAGTTGACAGAGGAAGAGAAGACTAGGGCCTGGT TCACAGATGGTTCTGCACGATATGCAGGCACCACCCGAAAGTGGA CAGCTGCAGCACTACAGCCCCTTTCTAGGACATCCCTGAAGGACA GCGGTGAAGGGAAATCTTCCCAGTGGGCAGAACTTCGAGCAGTGC ACCTGGTTGTGCACTTTGCATGGAAGGAGAAATGGCCAGATGTGC GATTATATACTGATTCATGGGCTGTAGCCAATGGTTTGGCTGGAT GGTCAGGGACTTGGAAGAAGCATGATTGGAAAATTGGTGACAAAG AAATTTGGGGAAGAGGTATGTGGATGGACCTCTCTGAGTGGTCAA AAACTGTGAAGATATTTGTATCCCATGTGAGTGCTCACCAACGGGT GACCTCAGCAGAGGAGGATTTTAATAATCAAGTGGATAGGATGA CCCGTTCTGTGGACACCACTCAGCCTCTTTCCCCAGCCACCCCTGT CATCGCCCAATGGGCCCATGAACAAAGTGGCCATGGTGGCAGGG ATGGAGGTTACGCATGGGCTCAGCAACATGGACTTCCACTCACCA AGGCTGACCTGGCTACGGCCACTGCTGAGTGCCCAATTTGCCAGC AGCAGAGACCAACACTGAGCCCTCGATATGGCACCATTCCTCGGG GTGATCAGCCAGCTACCTGGTGGCAGGTTGATTATATTGGACCTC TTCCATCATGGAAAGGGCAGAGGTTTGTCCTCACTGGAATAGACA CTTACTCCGGATATGGGTTTGCCTATCCTGCACGCAATGCTTCTG CCAAGACTACCATCCGTGGACTCACGGAATGCCTTATCCACCGTCA TGGTATTCCACACAGCATTGCCTCTGACCAAGGCACTCACTTTA CGGCTAAAGAAGTGCGGCAGTGGGCTCATGCTCATGGAATTCACT GGTCTTACCATGTTCCCCATCATCCTGAAGCAGCTGGATTGATAG AACGGTGGAATGGCCTTTTGAAGTCACAATTACAACGCCAACTAG GTGACAATACTTTGCAGGGCTGGGGCAAAGTTCTCCAGAAGGCCG TGTATGCTCTGAATCAGCGTCCAATATATGGTACTGTTTCTCCCAT AGCCAGGATTCACGGGTCCAGGAATCAAGGGGTGGAAGTGGAAG TGGCACCACTCACCATCACCCCTAGTGATCCACTAGCAAAATTTTT GCTTCCTGTTCCCGCGACATTACGTTCTGCTGGCCTAGAGGTCT TAGTTCCAGAGGGAGGAACGCTGCCACCAGGAGACACAACAACG ATTCCATTAAACTGGAAGTTAAGATTGCCACCTGGACACTTTGGGC TCCTCCTACCTTTAAGTCAACAGGCTAAGAAGGGAGTTACAGTGTTGGCTGGGGTGATTGACCCGGACTATCAAGATGAAATCAGTCTACAttorney Docket No. 60448-717.601SEQ SequencesIDNoTACTCCACAACGGAGGTAAGGAAGAGTATGCATGGAATACAGGAG ATCCATTAGGGCGTCTCTTAGTATTACCATGCCCTGTGATTAAGG TCAATGGGAAACTACAACAGCCCAATCCAGGCAGGACTACAAATG GCCCAGACCCTTCAGGAATGAAGGTTTGGGTCACTCCACCAGGAA AAAAACCACGACCTGCTGAGGTGCTTGCTGAAGGCAAAGGGAATA CAGAATGGGTAGTAGAAGAAGGTAGTCATCAATACCAGCTACGAC CACGTGACCAGCTGCAGAAACGAGGACTGTAATTGTCATGAGTAT TTCCTCCTTCTTTTGTTAAAAACATGTTTGTGCATGTATACACTT GTACTAAGAAAATATCTTCATTTTATTTCCTTTCTCCTTTATCATGT GACATAAGATTTATTGACTTCATATCAGCATTTAAGTATTGTT AACTTTATGTAATAGTATTTGGGTTGGGGATTGGTGCGTTTCCGGT TGTACGAAGGATAGTTGTATTATGTTAGGCGTAATTATGACCTT ATTATTGTCTTTATTTGAAGATTATGTATGATCTCAGGAGATGTGT ATGGGTTCAAGTTGACAAGGGGTGGACT22 ATAGTCGGCAGGATCCCGAGGTGAGTGAGCCTTCGGCCCCCGATG Consensus ATCCCGGGTCGGCCATGTGGCCGCAGCATGGGCTGTGGTACCCGG sequence for TGGCAGCCGTGCTGCTCGGATGGGCCCCGGTGGAAACNTGGGCGG transposable CGGTGGACGGGTCCCCCGCGAGCGTGGAGAAGGCGCTGAAGCAGC elements that TGGAAGCGCAGAGCACCGAGAAGGAGCGCGCCTTTGCCGGCAGA belong to GTCGGATGGGCGTTTTTGACTGCGCTACGGGAAGTACACGCCCAG TCCCTGCGGGATGCAGCGCAGGTAAGGGACCTCCAGGCGCAAGCG HERVL18 GGGCGCCTGGAGGCCCGGNTACACAGCTCGGAANAAGANTTGGG subfamily GGTAAGGGACCTCCAGGCGCAGGCGGGGCGCCTGGAGGCCCGGNT ACACAGCTTGGAANAGGAATTAGAGGCTGCCGTNAGTGCGGGCCT GGGCCCGTCGTCCCGGCCGGAGACCCCCGCTCGGTCTGATACCGA GGAGGAAGAACCCCCCGTTGCGGGCTCGCCCAGTGGTCCGTCAGA AGGTAGANCATGAACAGCCGNTGGGGCCCCAAGGGCGGGCTCAG GGACCCCCCACCGTGACGGAACACACTTCATATAGTGCCTATACCC CAACTGAGTTGCGGGAATTAGGCAAGCAGTGCCGGCAGCGTCCGG GGGAACCCCTGCCCGCCTGGATGCTTCGTCTNTGGGACGAGGGAG CNGACAGTATTTCCTGCTCCGCCTCTGAGATGGAAAAGCTGGCCTC TATCACGACTCACCCCTCCCTCCGTCAGCGGTTGCAGGTGAGCAGG CGGTTGGCACAAGGGCAAGGTGACCACACCCTGATTGAGTGGCTG ATGGCAGCCATACGGACTGTGTGGAACGACGCCGGNGAAATACCA GAAACTGTGAGTAAATGGCAGTCGTATACCGATTTGGTGCAAGTN ATCCGGGAGATGGGTATGCGGCAGGCTATGTTTGATCTGAATACC CGGGGGCCAGATGATGAACGCTTTACCTCCCACATGAGGGATCTC GTGTTGGGCTCTGCGCCCCCGAGTGCCTTTGGCTCCCTAGCCGCT GTCCTCACCCCGTACGTGGGGCGCCGCATACATGAAGTGACTACT GCTATGGCGGCCCTCGGGGAAGCAGAAGGCCATCGGCGGGACCGG GGGGTCCGCGCCATAAAGAAGGGGAAGGTGCCCCNCCCGCAGGG GGCCACCCCACGGGANAAAAGGGGGCCCCAGCGGGTGACNCGCN CGCAGATGTGGATNGATTTGATTTCGGCCGGGGTTGACCGAGAGA AAATTGATAGGCAGCCCAATGAAGTGCTGTTAACTTTGTGGAGGC AATTGTCCCCGGAGCAGCAATTCCGGAAAATGCCCAAGGGGGGGN AGGACANTGCTGCGCGACCCAGTCCCGCCCGGGCGCTCCAGCTCA AGGACTACTTGCAGNCGGGCGGAGATGTAGAGCCTTTTCTGTTTGA TTAGGGAACTGGCCGAGGTGCCCGGCTTGGGGGGACACCGGACGA CCGGAGGCCACATGTGGAATTGGCAATCCACTGGTCCCCCACCAA TGTACAGCGGGTGCTGGCGCTGGTAGATACTGGCGCAGATTGCAG CCTCGTTTATGGGAACCCGGATAAGTTTCCGGGCAAAGCTGCATAC ATTGACGGTTATGGAGGCCGGTCAGTGAAAGTGAAACCTGTATCT CTGCACCTTGGCATCGGCCGCTTGGCTCCCCGCTTATACACTGTGTATGTCTCTCCCATACCTGAATACATTCTGGGGGTGGACGTTTTAAttorney Docket No. 60448-717.601SEQ SequencesIDNo CACGGCTTGGNCTTACAAACCACGGCCGGAGAATTCAGACTCCGA GTNCGTGTGGTGAAGCCGGTGCTGCGTGGACATACGCATCACCAG CCCCAGGTCCTGCCACAACCCCGACGGGTTACTTCCACCCGTCAAT ACCGTTTGCCGGGTGGGCATACGGAGATAACTGAGACNATTAAG AAGCTGGAGGAGGTGCAGATAGTGCGTGGCACCCACAGCCCCTAC AATTCTCCGGTATGGCCAGTCAGAAAGCCTGATGGAACTTGGCGG ATGACGGTGGACTATCGGGAACTGAATAAAGTAACACCCCCTTTG CATGCAGCTGTGCCGTCTATCACGGATTTGATGGACCGCTTGACG ACGGAACTGGGACAGTACCACTATGTGGTGGACTTGGCCAATGCA TTCTTCTCCATCGACATTGCTCCAGAGAGCCAGGAACAGTTTGCC TTCACGTGGGAGGGGCGACAATGGACTTTCACAGTGTTGCCGCAG GGCTATGTGCATAGCCCCACCATATGTCATGGTCTTGTTGCCACG GATTTAGCCGCCTGGNAATGTCCAGAAGGGGTCCGCCTATTCCATT ATATTGATGATATTATGTTAACCTCTGATTCTCTTGCAGATTTA GAAGCGGCGGCGCCCCTCTTGCGGCAACATTTGGCAGCATGCGGT TGGGCCGTCAACGAATCCAAGGTCCAAGGGCCTGGATTGTCTGCC AAATTCTTGGGAGTTATCTGGTCGGGTAAGACGAAGGCCATACCA GAGGCCATCATTGATAAAATTCAGGCATATCCCCGGCCCACCACG GTGAGGCAGCTGCAGACTTTTGTGGGCCTCCTGGGATATTGGCGG GCATTTGTGCCCCATTTGGCTCAAATGATAAAACCGTTGTATCGG TTAACAAAGAAGGGAGCTACCTGGGATTGGGATGATGCGGCTGAG ACNGCCTTCCTGGCAGCCAAGCGGGCTATTCAGCAGGCACAAGCC CTACGGGTAGTTGACCGGGGCGCCCATTTGAGCTGGATGTGCATGT GACCACAGATGGTTTCGGCTGGGGCCTATGGCAGCGCACGGAGC GCTTGAGAACGCCAGTAGGCTTTTGGTCCCAACTATGGAAGGGAG CTGAGCTCCGGTATTCNTTGATAGAGAAGCAGTTAGCAGCTGCAT ATGCCGCCCTTCAGGCTCGTGAGAGCGTGACAGGACGGGCTACAG TCGTCGTGCGGACGACTTACCCAATAGCGGGATGGGTGCGTTCAT GGGTAACGACCCCCCGGACTGGGACGGCGCAGACATCCACTTTAG CAAAGTGGGGCGCCTACTTGGAGCAGCGGAGTACGCTGAGTACAA GTCCCTTAGCAGCAGAGTTGCAAGAGGTCTTGGGACCTGTAGTCCT AATGCAAGATAAGGCCATGGGGCCTGAGGCACCCCTAGACCCTG AGCCTTCACCGTTTAAGGAAGGGCGTCCCCCCATTCCCGATGGGGC ATGGTACACAGATGGGTCTAGCCGGGGTGCTACTGCTGCCTGGA CCGCTGTCGCAGTCCAGCCTAGTACTGACACCATATGGTTTGANAC CGGGTGTGGACAAAGTAGCCAATGGGCTGAACTCAGAGCAGTGT GGATGGTGATCACCAAGGAGGTGACACCTATGGTAATCTGCACCG ATAGCTGGGCAGTTTATCGAGGCTTAACTTGTGGTTAACTACCTG GAAGTTACAGAANTGGCTAGTTGGCCACCGGCCCATNTGGGGCCA AGCCATGTGGCAAGACCTATGGGAAATGGGTCATCAGAAAGANGT AACTATTTATCATGTGTCAGGCCATATGCCTTTGGCCACCCCCGGC AATGATGAGGCAGATGCCTTGGCCAAGGTCCGATGGTTAGAGTC GGCACCTACACGAGATGTGGCCTTGTGGCTACACCGGAAACTGGG ACATGCGGGGGGTAAACTGATGCAACAGGTCAATAAGCGTTGGGG TCTGTCCCTGCCCACGCAAGACATTTGGGAGGCTTGTCAGAAATGC CCGGCATGTGCTCAGGCATACCCTAAACGGAGGCAGCTGCCCAG TGTTACACAACAAGTGACGATAGGGCGGGTGCCCTTGACCAGGTG GCAAGTAGACTACATCGGGCCGCTGCCGAAGTCGCAGGGGTATAC GCATGCGCTGACGGCTGTGGACACGGCCACAGGCCTGTTGTTCGC CTACCCTTGCAGGGTGGCCGACCAACAGCACACCATCCGGGCCCT GCAACACTTATGTGCCCTGTATGGTCGCCCTCTGGCCGTTGAGAGT GATAGGGGAACACATTTCACTGGACAACAGGTACAACAGTGGGC ACAACAGATGGACATAAAGTGGGGATTCCATGTGCCATACAACCCGCAAGCCGCGGGTATGATTGAGCGATATAACGGGCTCTTGAAGAAAttorney Docket No. 60448-717.601SEQ SequencesIDNoTGGGTTACGCTTGCATGTCACNCCCCCGTCTTTGCGGGGCTGGAGT TCCAGGCTGGACCTGGTGCTCCAAACCTTGAATGAACGGCCACG GAAAGGCGGCCCGGCCCCGGTGGAGGCNTTGTTACACCGGGCCGC CGCCCCCATTCAGTTGCAGATACACACCAAGGATGACCTCCTCCG ACCAGGTATGGGGACGAACGGTAACCTGTTGTTGCCTGCCCCAAC GCCCCTGAAGGCAGGGGAACAGAAAACCTGGCTTTGGCCATGGAC CCTCCAAGCCCCCCACTGCCGGTGGTTGGCCATCGTAGCCCCCTGG GGGGAGGGCCTACAGTATGACTTGCATGTCACTCCTTGGGTATT CAATGCGTGGCCCCCGCGGTTGACCGTTCGTAGGGGAACGGCCAG GGAAGGAACCCTCCTCCGGGGGACATATGTACTGTCTGTGTGGCC TATTATGAGCTCCCCCGTGACTTTGGCACGGATACAGGACCCAAA GGAACCATGGGGAGCTGAGAAGGTGTGGTACCATCGCCCAGGGCA GAAGCCCTTGGCGGCTGCATTGTTATCCAGGGATGAAAGGTTAGC CTGTATTTTGCCTGAGGGACGTGATTTACCCCTGTTAGTACCTGT GCCTGCTCTGTCGTTTCGGCCGTAGGTTGACATGCTCCAACNGCAT TGTGGACTGGGCCCACACCTACGCTGAGGTGACCAATGTTTCCA ACTGTTGGATCTGCACCGCCCTTCCAGCAGCAGCTGCGGACGGCTT GCCCTGGCACATACATCCAGCNTCTGCGGAGAACTGGACATGGC TGGAGACTTGGGGTCCCATGGCCGACGCCTGGAATGCAACGCGGC AAGCTTTGGACAGGGGGCGCCGCAAGACCCATGGCANCGCCCGCC CCCTGGCTGGCCCGTAGCGTCTATGATGGGTGGGGCTGGCTAGTG GGGGAACACGTGGTGCCCCCANCGCAGGTACCACGGTGCATAGAG CAACACTGGGGTAACGCCACTGTGGGATGGNTGCCCGCCGCGGCC TGTGCAAACATAACACGTGTCACCACACCGAAGGTGTGGTGGAAC AAGCGGCCCCACCAAGGCCGGGCCCCGATGGACTTTGTGCCCCCT GGGAGTTTATGGGTCTGTGGGGACACAGGGTGGCCNTACCTGCCA GCGAACTGGACTGGACGTTGTACCTGGGGGTGGCCTTATGTGCCTG CCACTGTTCTCCCCACATTGCCCAGACGCCCGCATAACTGGGAG GCGCTACGCTCCCGGTTTTTGCGAGTGCGGCGAGCCCCCTGGTGGT TCTACCCCTTGGCAATGACTATCCCTGGAGCGGGTGTCATNACT GTAGAAGCGCAAGTTACNGCCCTTGCAGAGCACACCGCTCGGGCC CTGAATTACACCCGAGTNGCCCTCCTCCTGTTAACNGATGAGGTT GATCAGATCAGAAAGGTGGTGCTGCAAAACCGGATGGCCTTAGAC ATAGTAACTGCTGCCCAAGGNGGCACCTGTGCCCTTTTAGGAACA CAATGTTGTACCTTTATCCCTGACAATCGGCAGAACATAACAGCAG CCCTGCAAGGGGTNTCACGGGAGATTAAGGCGGTCGAGAGCCTT ACTGACGACCCCCTGCAGAGATGGTGGGCATCCCTGGGCTCTGGC CTACGCTGGGCCCTAATAGTCATAGGTAGCATAGCNGGGATNCTA GTAGTGAGCTGTTGCTCTCTGTATTGTTGCTGTGGCCTATGGGTCC AGGGCTCCGCCCTATGGGCACGTGTCCCCGCCNAGAGGACNCCC TCGGCCTAGGGGGTGGA23 TGTTAAATACAGTGAGTTCCGAGTTTCTCTTCAAAGAACCAGTATG Consensus TCAGTATGTTCAGCTCCCCTGTTCTTTGTTCTCCATTTTAAAGT sequence for TTAACTTCCGTNNNTTCGNCTCNCCTGCTCCTTGTTCTCCATTNNAA transposable ANTTTNNCCCGCCAGTTCTAATCAGTAGTTCACATCTGTTCCC elements that CTGGTCACCTGCTCCGTCCTGAGTCACCCCTGGTCACCTGCTCTGA belong to CCTGAGTCACCCTTAGTCACCTGTTCTGTAACCGTCCTTCCCGC CAAACTACTCACCCCGCCACTCCGGCTCGTACCCCTGCTCTCTTTA LTR10A AAATAGCCAATCGGAATTAGCTTAGACTGTGCGGTCCAACCCTA subfamily GCCAATAGGGGAACGACACAGCAGTAGGGGCTACCTGCGTCAGGA ATAAGAACCCCTTCCCCTCCCTTGTCCAGGTGTGCTCTCGCCATT GCTCCATCCGCGAGNCGCACCCTTCTATAGAAGTAAAATTGCCTTGCTGAGAAAATTAAATTTATGTTCGAGTGCTATTTCTTTTGCGGCAttorney Docket No. 60448-717.601SEQ SequencesIDNoACCGAAACAAGCATTAAATTTATGTTCAAGTGCTATTTCTTTCGCG GCACCGAAACTTTACGTATAACA24 TGTAGAAAGTAAAAAGTTTCCTCTTCAAAGTTTCCCTTCTTGTTAA Consensus AGAATAAATCATAAGTGTTAGAAATAATAGTTTCTTTTAAAGAC sequence for TAACTTCCTTCAAGCCTCCTTGCTTTGTGCTAATAACTCTTTGTTAA transposable GCCCTATCCTATGTAGCTGTTAGACATAGGGAATAAGTACATT elements that CTATGTCCTTGTACTTTAACCAAGATATTTGTGCTGGACGTGCTCA belong to CAGGCACGTCCCAGCTCGCAGCCTATGCCCCTTCCTTATTTGGA AATGTTATTGCTTCTCTAAGTCCTTTCGTAAGCAACTTCCTCTTTTC LTR10E CTTTGTTCTCCCTTGCNTTTACCTATTTAGGAAAGTTTTAAGT subfamily TATTAGCCAATCGGGTNTCAGTTTAGATTGTGAGGTCCGGCTCCAG CCAATGGAGACAGGACACAGCAGCAAGGACAAACTGCGTAAGGG ATAAANATTGCTTCCCTCCTTTGTTCAGGTGTGCTCTCGCCATTGTT CCATCTGCGANGAGCACCCTTTCTGCAGAAAGTAAAGATTGCC TTGCTGAGAGAACTTTTTGTCTGAGTGCTGACTTTTCTTTGCGGCAC CGAGGAACAAGCATTCTGTTTCTAAATAAACATTTTACTTATA ACA25 TGTGGGCGGCAAGCCACCCAGGCGCCGAGGCAAGAGACCGAGGG Consensus CACGAGCTGTTCCAGTATAATAAAATATATAAAACAAGAATAGTT sequence for ATACCAGATATAGATCTTAGATATGATTATATATGAATATCATTAA transposable TCATTAGTTTGTAGCAATTACTCTTTATTCCAATATTATAATAAT elements that CCTCGCTCTATAATCATAACCTAGGAAAAACCAGGCCATACAGAG belong to ATAGGAGCTGAGGGGACATAGTGAGGAGTGACCAGAAGACAAGA GTGCGAGCCTTCTGTTATGCCCGGACAGGGCCACCAGAGGGCTCC LTR13 TTGGTCTAGCGGTAACGCCAGCGTCTGGGAAGACGCCCGTTGCCA subfamily GGCGGACCGTGGTCTAGCGGTAGCGTNAGTGTCAAGGAAAAACAC CCGCTACTTAGCAGACCGGGAAAGGGAGTCTCCCTTTCCCCGGGG GAGTTTAGAGAAGACTCTGCTCCTCCACCTCTTGTGGAGGGCCTGA CATCAGTCAGGCCCGCCCGCAGTTATCCGGAGGCCTAACCGTCTC CCTGTGATGCTGTGCTTCAGTGGTCACGCTCCTAGTCCGCCTTCAT GTTCCATCCTGTACACCTGGCTCTGCCTTCTAGATAGCAGTAGC AAATTAGTGAAAGTACTAAAAGTCTCTGATATGCAGAAATAATGG CGTAAGCTGTCTCTCTCTCTCTCCTCTCTCTCTCTGCCTCGGCTG CCAGGCAGGGAAGGGCCCCCTGTCCAGTGGACACGTGACCCACGT GACCTTACCTATCATTGGAGATGGCTCACACTCCTTACCCTGCCC CTTTGCCTTGTATCCAATAAATANCAGCGCAGCCNGGCATTCGGGG CCACTACCGGTCTCCGCGCCTTGGTGGTAGTGGTCCCCCGGGCC CAGCTGTCTTTTCTTTTATCTCTTTGTCTTGTGTCTTTATTTCTACAC TCTCTCGTCTCCGCACACGGGGAGAAAANCCCACCGACCCTG TGGGGCTGGTCCCTACA26 TGTAGTGGATGCTGTGGTGCGCCGCCCAGATCGNNCCCCCCTTCAG Consensus GACCGAGGCACTCATTCCCCCAGCTGCCGGGAGTGTTGGCTGCT sequence for GACGGCTCNCAGCTGAGTCCCTCTCCGGGAATTGCCCTCGGCCGA transposable AGGGAGCTGCCTCGCCCAAGGTTACGCCCCCTTCCCGGGGGCAGC elements that CCGCATCCAATGACTGGTCGATGCGGGGGTACAAAGGCCTCAGTC belong to CTCAATTCGGGACAACTCTGAAGGGCCATCCCAGCTCCAGAGCTC CCCGTGGGATCGGCTGAGGCCTCTGTTGCGACTGCATCGCAGTTCA LTR16 ACTTCTCCCTCTGCCCAATCCTGCTTCCTTCACTCCCTCACAGG subfamily TGTTGNTCCCGAGAGCACTCCCCAATAAACCTCCTGCACGCAAATC TCCGTCTCAGAGTCTGTTTCCCGGGGAACCCA27 TGTGGTGGACGCTGTGATGCGCCGCCCAGATCCCCCTTCAGGANTG Consensus AAGGACTTATTCCCCCAGCTGCTGGGAGTGCTGCCGGCAGACAG sequence for CCCTCAGCTGTCAGCCCTCTTCGGGGATTGCCTCAGCTGAAGAGAG transposableCCGCCTCGCCCAAGGTCACGCCCCCTTCCCGGGGCAGCCCGCATAttorney Docket No. 60448-717.601SEQ SequencesIDNoCCAATGACTGATCGATGCGGGGGTATAAAGGCCCGGCCCCCTCGC elements that CCCAACTCGGGACAACTCTGAAGGGCCATCCCAGCTCCAGAGCTC belong to CCCGTGGGGTCGGCTGAGGCCTTCGTTGGGACTGCATCGCAGCTCA LTR16A ACTTCTCCCTCTGCCCAATCCTGCTTCCTTCCCTTCCCTTCCAC subfamily AGGTGTTGATCCCAAGAGCACTCCCTAATAAACNTCCTGCACGCTA ATCTCCGTCTCAGAGTCTGCTTCCCGGGGAACCCAACCTGCGACA28 TGTAGTAGATGCTGTTGGTGCCCCGCCCAGATCCCCTTTACCGGGC Consensus CGGTGCACCCATCCCCCAGCTGCTGTGAGTGTTGGCTGCTAACG sequence for GCTCACAGCTGCCCCCTTCTCCGGAGAATTGCCCTCGGCCGACGGG transposable AGCCGCCTCGCCTGGGAGGTTACCCCCCACCGGGCAGCCCGCAG elements that CCAATGACTGACTGATACGGGGGTACAAAAGGCCGGCCCCCTTGC belong to CTCAAGGTGGGACAACTCACTCTGTGGTGCAATTCATGCTCCAGA GCTCCCCGTGGGATCAGGCTGAGGCTAGACTTCAGCTGAGACCAC LTR16A1 ATCCTTGCTTAGCTTCTTCCCCTGCCCTATCCTGCTTCCCTCACT subfamily CCCTTACAGGTTTCTCCTGAGAGCACTCCCTCAATAAATCACTTGC ACAAGAATCCCCGTCTCAGGCTCTGCTTCTAGGGAACCCGACCT AAGACA29 TGTAGCGGACACTGTCGGTGCCCGCCCAGATCCCCTCGGATCCCTT Consensus TTACCGTTTCTGTGCGCCCCTTCCCCAGCTTCTGTGTGCTTTTG sequence for CTTCTAACGGCCCGCACCTGCGACTCTTTTCGGAGGACTGCCCTCG transposable GGCTACTGGAGCCGCTTTGCCCGCATGCAGAGAGCCGGAAGTGC elements that CTGGGAGTTTATGNCCTCTTTCCCTCCAGGGCGGCCCTTAGCCAAT belong to GACTGACTGGTGCGGGAGTATGAAAGCCCAGCTCCCTTGCCTCG AGTCGGGACAAACTCTGAGGCGTAATTTACACTCCAGAGCTCCCCT LTR16A2 GCGGGATCAGGCTGAAGCTGGGACTTTGCCTGAAATCGCACCCT subfamily TGCTTGGCTTCTTCCCCTTCCCTGTCCTGCTTCCCCACTCCCTTACC GGTTTCTCCTGGGAGCACTTCCTTAATAAATCACTTGCACACG AATCCTCGTCTCAGGGTCTGCTTCTGGGGAACCCGACCTAAGACA30 TGTGGCGGCCATGAAAATGCGCCGCTCAGATCTCCTGCTGCGGGG Consensus AGCATAGTTGACTGACGGCCCCAGCTGCTGCCCCTCTGGATCCAC sequence for CACCGCGTTCGCGCCGAGGCCACGCTTCCCNCGGGCTGCTCCCAG transposable CCAATGACTGAGCACGGCGGGGGTACTAATGCAGGCCCATTCCTG elements that CGAGACGCGGGACTCCTCTAACGGGCGACTTTGGCTCGAGGACTC belong to CCCATCGGCCTGGCCGAAACTTTCTTAGAACTGCGCTGCAGTCTG AGACTCTTCCTACCCAATCCTCCTTCCTTCCCCCTCTCCTTCACAGG LTR16B TGTCAGACCTGCATCGCGGTCTGAAGGCTCTCCCTGCCTNCTC subfamily CTGCTCCCTCCCCTTTATCCTTCACAGGCGTTTCCCCCAATAAATCT CTTGCACGTCTAATCCCGTCTTGGCGTCTGCTTCTCGGAGGAC CCGAACTAACACA31 TGTGGCGGCCATGGAGGTGCGCCGCTCAGATCTCCCTTCAAGAGA Consensus ACCTGCTGCGGGGAGCGTAGTTGGCTGACAGCCTCCAGCTGCCGC sequence for ACCTTCGGATCCGCCGCAGCGTTCACGCCGAGGCCACGCTTCCCCC transposable GGGCTGCTCCCAGCCAATGACTGAGCACGGCGGGGGTACTAGAG elements that CCGGGCCATTCCTGCCCGACGCGGGACTCCTCTAACGGGCAATCTT belong to TGCTCNGGGACTCCCCATCGGCCTGGCCGAGACTTTCTCAGAGC TGCGCTGCAGTCTGAGGCTCTTCCTACCCAATCCTCCTTCCTTCCCT LTR16B1 CTCTCCTTTCACAGGTGTCAGACCTGCATCGCGGTCTGAAGGC subfamily TCTCCCTGCCTACTCCTGCTCCCTCTCCCCTTTATCCTTCACAGGCG TTTCCCCCAATAAATCTCTTGCACGTCTAATTCCGTCTTGGCG TCTGCTTCTCGGAGGACCCGAACTGACACA32 TGTGGCGGCCATGAGAATGCGCCTCTCAGATCTCCNACTGCAGGG ConsensusAGCGTAATTGACCGANGGCCCCAGCTGCTGCGCTCTGAATCCATC sequence forAttorney Docket No. 60448-717.601SEQ SequencesIDNoACCGCGTTTGCGCCGAGGCCACGCTTCCCACGGGCTGCTCCCAGCC transposable AATGACTGAGCGCGGCAGGGATACTAAGGCAGGCCCGTTCCTGG elements that GAGACGCGGGACTCCTCTGACGGGCGACTTTGGCTCGAGGACTCC belong to CCGNCGGCCTTGCCGAANCTTCCTTAGAACTGCACNGCAGTCTAA LTR16B2 GACGCTTCCTACCCAACCTTCCTTCCTTCCCTCTCTCCTTCACNGGG subfamily GTCAGACCTGCATCGCGGTCTGACGGCTCTCCCAGCCTCCTCC GGCTCCCTCCCCATTTTCCCTCACAGGCGTTTCCCCTAATAAATCTC TTGCACGTTTAATCCCGTCTTGGCGTCTGCTTCTCGGAGGACC CGGACTAACACA33 TGTAGCAGACGCTGTCGGTGCCCCGCCCATATCCCCTCGGCCCTTA Consensus CCATTTCAGTGCACGCCGGCCCGACTTCCAACTGCCAGCACCTG sequence for CATCTCTTTGCCTGAGGGCTTTCTCTGGCCGCCGGAGCCCGCTCTG transposable CCCACGCGCANGGCAGGCCGGAAGTGCCGGGGAATTAACGCCCC elements that CCGGGAGCAGCCCTCAACCAATGACTGACGGGAGTTGGTGNATAA belong to ATACCCCAGCTCCCTCGCCCCTCGGGTGGGATAACTCTGAGGCGC GTGTTCTACACTGTCTCCCAGAGTTCCCCAGCGGGATTGAGCTCCA LTR16C GTTGCCCACAGTGGTAACTTGCTCGATAACGCACCCTTTATTGG subfamily CTNCCTTCCCTTCCCTGTCTCACTTCCCCACTCCCCTACCGGTGTTT CCTGGGATCACCTCCCAAATAAACTACTTGCACTCGAATCCTT GTCTCAGGGTCTGCTTCTGGGGGAACCCAAACTAAGACA34 TGTATCGGACACATCTTATGCGCCTCCTCAGATTCTCTCGGCCTCA Consensus CCTGTCTCCCGGACCCTCGGCCGCTTGCTCTGCCTCAGCCGCCG sequence for CCGCGGCCGACCGACTCCGTGCGGGCCCATGCGGTTCCGCCGCCT transposable GAGGCCGACCAGCCACATGCCCGGAGTCTCTGGCTCCTCCCGCCA elements that CTTCCGGACTCGGATGAAACGCCACACCGCAGGGCGTGGGATCTG belong to GCTTCCCNAGCGGCTGCCGAAGGGGCCGGATGACGCAACCCGGAA GTGCGGGGGAGTTAACTCCCCGTGGGGCGAACTTTGACCAATGGG LTR16D AGACAGGAGACGGGAGGGAGCCGGGCAGATAAATTCCCTCTCCTT subfamily CCCTCCCTCCATGGACTGTTCCGAGGCACGGTTTCTCCGTACAGCC TGTCCGGAGACGTCCCGCGTGGCCGAGCGGATGCACCTGCCGAG CGACCGGCTGTGTCTCTTCGCGGCTCGTCGTGAAGCNGTGGCCAGC NCGGTAACGCATCACCTTGCATTGCTTCCCNTCCTTCCCTGCCT CACTTCCCTTTTCCCTCACTCTCGCTGCCCTGGGATTGCACCTCCCA AATAAAGCATTAGCACNTAANCTTTGCCTCAGGCTCTGTTTTC TAGGGAACCCGGGCTAAGACA35 TGTATCGGACACAAACCTTGTGCGCCTTCTCAGATTCCCTCGACTG Consensus CCTCCTTCTTCCGAAGGTGCCGCCTCCTNCCCGGGCCACTCCGC sequence for TGCCACCGCCTTTGCTGAGCTCCCTGAGCTGGCTGGAGTCCGAGTT transposable GAAGCCCCGGGCCTGCATGGCCCTCAGTCCCACACGCCGAGCCC elements that CATCCGCGCCGAGTCGCCCCTCCACTTCCGGACTTGGATGAAACGC belong to CACACCGCGGGGCATGGGATCTGGCTTCCTGAGCGGCCGCCGAA GGGGCCGGATGACGCAACCCGGAAGTGTAGGGGAGTTAGCTCCCC LTR16D1 GTGGGGTGAACCTTGACCAATGGGAAACGGGAGACGGGAGGGAG subfamily CCGGGCAGATAAATTCCCCCTCCTTTCTCCCTTCCGTGGACTGCTC CGAGGTGTGGTTTCTCCTTGCAGCCCTTCCGGAGAAGTCCCGCGT GCCGAGCGAACACGCCTGCCGAGCGACCTGCTGTGTCTCTTCGCG GCTCGTCGTGAAGCGGTGGCCAGCGCGGTAACGCATCGCATCGCA TTGCTTCGCATCTTTCCTTGCCTCACTTCCCTTTTTCCTCACCCTCAC CGCCCTGGGCTTGCACCTCCCAAATAAAGTGTCAGCACTTTA ATCCTTGCCTCAGGCTCTGCTTTCTAGAGGACCCGGGCTAAGACA36 TGTATTGGACACAAACCTTGTGCGCCTTCTCAGATTCCCTCGACCG Consensus CCTCCTTCTTTCTCTCTCTTGGCCGGCGCCCCACCCGCGCCGGG sequence for TCGCCCCTCCACTTTCGGACTTGGATGAAACGCCACACCGCGGGGC transposableATGGGATCTGGCTTCCTGAGCGGCCGCCGAAGGGGCCGGATGACAttorney Docket No. 60448-717.601SEQ SequencesIDNoGCAACCCGGAAGTGCAGGGGAGTTAGCTCCCCGTGGGGTGAACCT elements that TGACCAATGGGAAACGGGAGACGGGAGGGAGCCGGGCAGATAAA belong to TTCCCCCTCCTTTCTCTCTTCCGTGGACTACTCCGAGGTGCGGTTCC LTR16D2 TCCTTGCAACCCTTCCGGAGAAGTCCCGCGTGCCGAGCGAACAC subfamily GCCTGCTGAGCGACCTGCTGTGTCTCTTCGCGGCTCGTTGTGAAGC GGTAGCCAGCGCGGTAACGCATCGCATCGCATTGCTTCGCATCT TTCCTTGCCTCACTTCCCTTTTTCCTCACCCTCGCCGCCCTGGGCTT GCACCTCCCAAATAAAGTGTTAGCACCTTAATCCTTGCCTCAG GCTCTGCTTTCTAGAGGACCCGGGCTAAGACA37 TGTAGCAGACGCCTCTGGTGCCCCGCGTCACATCCCCTCGGCCCAC Consensus CTCTGATTTCAGCCGCAGCTGCGGTGGACAGTTCCGTGCGAGCT sequence for CAGACTCACCTTTGCTGACAGCGTCCCACCTCAAGCGCGCGCCGTG transposable CGTCTTTCTGCTTTCTGCCCCAGGGCCTTCTCCGACGCCGCGGG elements that AGCCCGCTCGGCCCGCGCGCAAGCGCAGCCCGGAAGTGCGGGGG belong to AGTTAACGCCCCCGGGGGCAACCCTCAACCAATGGGGGACGGGAG CCGGTGGATAAATGCCCCAGCCTCCCGTCCTTCAGGTGGACAATTC LTR16E1 TGGGAGGCATTCTGTACGCTTCTCAGGAGGTCCCAGCGGGATCGA subfamily GCCCCNGTTGCCCACAGCGGCGACCTCGATAACGCACCCTTATATT GGCTTTTCCTCCTTCCCTGTCTCACTTCCCCGCTCCCTCACTCC TGCTTCCTGGGATCACCTCCCAAATAAACTACCTGCACCCAAGTCC TTGTCTCAGGCTCTGCTTTCGGGGGAACCCAAACTAAGACAG38 TGTATCGGACACCTCTTGTGCACCACTTCANATCCTCTCGGCCCCA Consensus CCTCTTACTCCAGCCACTGCTGCGGCGACCAGTTCCGCGCAGGC sequence for TTCGACCAGCTTCGCGCAGGTGCAACCTGACAGCGCCTCGCCTCAG transposable GCCCGCGCCGCGTACCTCTCGCTTCCTGCCCCGGGGCTTCTCTG elements that ACGCCGCGGCGTGGGACGCCTGCGGGAACCCGCTCGGCACTCACG belong to CATGCGCAACCCGGAAGTGCGGGGGAGTTAACGCCCCGTGGGGCA ACCCTTGACCAATGGGGGACGGGAGCCGATGGATAAATGCTTCCC LTR16E2 CCTTTCGTCCCCCGGGCGGACAGTTCTGAGACGCATTTCATANGG subfamily CTCCTCAGAAGGTCCCGGCGGGATCGAGCACCAGTCGCCCACAGC GGTGGCCAACTCGATAACGCATCCTTGTATTGGCTTTCCCTCCTT CCCTGTTTCACTCCCCCTGTCCCTCACTCCTGCTCCCTGGGATCACT TCCCAAAATAAACTACCTGCACGCAAGCCTTTGTCTCAGGCTC TGCTTTCGGGGGAACCCAGGCTAAGACA39 TGTTATAGGAGATAGAAAGAAATTATTTAGGTAGACAGTTAGGGT Consensus AAAGNGAGTCCCCGGCAGAAAACTTTCCTTCTAACAAAAAGCAGC sequence for TCAGAAATAGCTCCCTTTCTAACCNCACGCAGTTCAAAGAAATCAC transposable TTCTCTTCTAACAAAGAGCAGCCTGGAAGATCAGGCTGTAAAAC elements that ACAGATAAGCAACTCNGGCACAGAAGGAGNGGGGAGTCTCCTGG belong to GTAATCACCAAACTTCACACNCATACGATGGGCCCCAGTAAAAAC AGTGGGCCTTAATAAGCACATTCCTTTCCCTTTAGGCACACTAAGA LTR19C TAGGGAAGCTGGAAGCGGACTGGGGGGGGATGCCTGCAGCTGCA subfamily AGAAGATGCCTGGGAACAGGCACGGAAACTCTCCCTCCCAGATAA GCAAGACAAAGCAGCGCGGAGCAGCAGACTAAGAGCCCGCCTGC GTGATCAAGGAATGGGGTGGGGGCTGNTAGAAAACTCTGCTCTAT GCAGATGGCACACCTGGTCCCAACCGAATCTTCGGGCCCTANGNG GATAAGACACCCCCTCCTCACTAGCCCCCTCCTCACTAGCCCATTT ATAAAAACCCTGACATTTTTACTGCAGCNCGGCAACCCGTTCGGG ACCCCTCTCTGTGACAGAGAGCTGTTCTTTCCTTTCGCCTATTAAAC TCCTGCTCCAANCTCACCCTGTGTGTGTGTGTCCGCGNCCTCGA TTTCCTTGGCCGTGAGACCAAGAACCTTGGTATTTACCCCAGACAA CGAGGCTGCTTCA40 TGTGAAAATAAGTAATTCAAAATCTAAGCTGTTGGAACTTTAAATT ConsensusATTTTGAGCCTTAAAGGAATGTGATTATGGGGCCTGAGTCACGT sequence forAttorney Docket No. 60448-717.601SEQ SequencesIDNoGACAGGCAGCTGTAACCTAGGCAGCTGTAACCTTTGTTTCTCTGAT transposable TATAGATTANGCCTTCTTCCTTACCTACATTGTTTTGTAAAATG elements that TTGTAAATGACTAAAGGGCGCCAGGGAAGACCCCTTCCCTCTTCAC belong to TGTTGATCTTCATTATAGATTAACTTCCCTCTTACCTCTCTCAC LTR24C ACAAAGACTTCATGACTATCACATTGTCTTAAGATGGAATGTTAAA subfamily TACACTCTTTTAAATTGGAAAGGAAATGAAAACAAGCTGTAAGG AAAAGAAAACAAGCTGTACGGAAAAGAAAANAAANCAAACTGTA ACTAACTAATTAAATTGTTGTAACTCATAAACCAGCCTTGTATAGA AAATGTTATAATCCTGCTAAATTTCTTTGTTTTCTGCCTATATAAGC AAGACCTTAACTTTTAACTTCGGAGCACTGACCCCATTTCTCT GGAGTCTGTGTTTCCCGGATGGCCATTCCCAGCTTTTCGCTTGAAT AAACTCTTTAAAACTGGATTCTGATCCTTTCGATTATTTCAGGT TGACA41 TGAAACCGTCCCTATAAACTTTATAAAATTAATCAGGGAAGAAGG Consensus GAGGGGGAGAAACGAAAATAAACCAAGCTTGCAGCACATTCAGC sequence for ATTAATCATTAGGTCAGCTTGCTCTCTGACCTGCTTCCTCATAGTTG transposable TTTGGTGCCTATTGCCCCAGAATCACGTAGACCCTGTTACAAGA elements that TTATAGTTCCCCTTAACTGCTCTATAGATAACAACTTGAACATTAT belong to GAAACGTTAAGTTTTCCCTTTGAGATATTCTTTCAGGTCCTGCA TACCGGTGAAACTACTGACANNCGNCGTCAGCTGGTCTGAAGGAC LTR26 CCCACGAGGAGCTGACTCACCAAAGAATGCAGTTTCCACATCCTG subfamily ATGATTTCATCCCCCTTACCCCGACCAATCAACGACCCCAATTTTC CAGCCCCTCGCCCTCCACGATCCCCTTAAAAACCCCAGCCCAGA ACTCCTCGGGGAGATGGATTTGAGGGTCTCCTCCCATCTCCTCGCT CGGCGCCCTGCGATCATTAAACTCTTTCTCTGCTGCAAACCCTG CTGTCTCAGTGTAATTGGTCTGTTACTGCGCAGCGGGCATACGAAC CTGTTGGTCCTATAACA42 TGTGCTGGATATTTTCCGTTTGCCCCTCCAGATCCACTCTCCACCCT Consensus TCTCCACCCTGCTCTGTGCCCCGGGAGGCTGACCTCTATGGAC sequence for TGCATCAACGGGCTCCCTTGCCCTCTGGCTTCCGGTTGGGTTCGGC transposable CAATGGGAGGCACCGGCAGGAGATCGGAGGGCGGGAGGAGAGTG elements that AGGTCGGGGTATTTATTCCCCCGGCTCCCTCCCTGCCGGGCCGCGG belong to NTTGGCAGTGGCTGCGTTCCTCTACCGAAGGCCACAGCTCCTGT CGGGCGGCCCTCTCCTACAGCTACAGCTCTCTCCGGGTTCCGGTAA LTR33 CCGCTCCCTCCCCTTGCCCCTTCAGGCCTAGGGGTGGTAACGGC subfamily TCCCCGCTGTTGCTAGCCCCGGGGTGCTTCACCATCCCTTGTTGGTT TCCCTTAACCCTGCCCACACCTTTGTAAATAGTCCCTTCATTA AACTCTCCTCAATTACCCCCGTTTGAGTGTGCCATCTGTTTCCTGCC GGGACCCTGACTGATACA43 TGTTGGGAGACAATCCTCCATGGGCCCCTNGCGCTCCTGCACGTCT Consensus TGCTGGGTATGCCAAGAATGCAAGGCCCTGACCGCTCTTTACCT sequence for CGGGCCATTTCTCAGGGTTGTGTTTGCAGCGAGCAACCTTGAGGGA transposable TGAGGTAATGTCTCCCTCCGGGACAAAGAGCAGGCTTGCTTACT elements that GCTTGCTATAAAAGCGGTGGATTCCCCAAGCTCAGTGTTCCTCNGC belong to TGTAACGCAAACCCACTGCGTGCGCAGCATCCATCTGGGCCCTC CGCGTCGCCCCCGTGGGACTTGGGGGGNCANGGGGAACCGACGCA LTR40c AACATGCTGATGCTCATGCTGCTTGCTGTGCCGTGAGTAATAAAG subfamily TCCTTTGTCTCTGACCCAGGAGTCTCGTGTCTTCTGCCAGCATCCAT GAAACAGTAACAGGCTAACTTATTAGCTTGTAAGTAGGGTAAA ATCCCAGACCTGACA44 GGTGTGCTTCTCTCACTTGGCAGGCTCCTGCAGCCAGGCACGGCTT Consensus CTCCAGCGCCCGGCTCCTGCAGCGCGCGCAGCTTCTCCAGCGCC sequence for CGGCTCCTGCAGCATGGCACTTCTCAGCATGCAGCTCCGCAGCAGC transposableAGTGCCAGCAGCTTCCCCCGGCACCCTCCTCGGGCGGTTTTGTAAttorney Docket No. 60448-717.601SEQ SequencesIDNoGCGGAGTGCCTCCGGTGAGACACCTCCCCGTGAACAGCTTTCCCCG elements that GCACCCTAGAGGGCGGATTTCCGGCAAGTTCCAGAGGGCGGATT belong to TCCAGCAAGTTCCGCCGGCGCGGCACCACAGCGACTTCTCTGCCAT LTR41 CCAGTGAGCCACGGCCGTGCCCTCTCCAACAAGGTCTGGATCTC subfamily AGCCCTGGGGGGAGGGGGCTCTTCCTTGGGCGCTCTATCTCAGCCC TAGGGGTAGTGGCTGCTCCTTATATCTGCTATTCCTATATTCTT TAGAGTTCTCTTTACTTCTTACTAGCCAATCCCTCGTTACTCCAATC CCCTGTTATAGTTAATAATTCTTTATATTAAACTTTCCCTGTT CAAATTACTGTGTGGTTTCTNTCTCCTGATTGGACCCNGACTGATA CA45 TGTGCCAGTTATCAATTTATTGCCTCTCAGCTCCAAATTCACCCTTC Consensus AATACCTGCTCTGCGATAATGGACTGGACTCTTTAAGCATTTC sequence for TCCTTTACAGTGAGCACGATGTTAAGCTTTNTCAGTAGAGGGCGCT transposable GGAGGGACATTGCAGGAGGAAGGGGGCTTCTCTTCCTGGTTCCG elements that GTGTGCTGCGTTTTGCTTTTTCTTGCTCCTGCTGCACGGTCGGTCAG belong to CGGTGCGGGTGTGTGGGGACATCCGGTGGTGCTCTGCCCCAGC CGCGCGCCCAGAGCGCGCAGTCCCTCGGCGACCTCGCAGCCCCGG LTR41B CCTGGGCCCGGTGACCACCTTCCCGCGGCCCTCCCGACGCGGACA subfamily CCGCGTGCTCCAGGCCTCGCGCCCGCAGCGGCGCCCCGACTCCCTC TGCGCGCCCGCCCACCAGCCTCGGCTCGCCTGCACCCCGGAGGG TTGCTTCCTGCTTGCCCAGCGACTGCGGACCAGCTCTGGCCCGGGC AANCCAGCGAACTTCTCTGCCATCCAGTGGGCTGCAACCACACC TTCTCCAACGAGGTCTGAACCCCAGCCTTGGGGAGGGGGCCCCCC TTCCAAGTTTGTCCTTCCTTGGGTACTCTCCCTCAGCCCTAGGGT ACCCTTTAGAGTTCTCTTTACATCTTATAGTTACTCTCCTATCATAG CTTAATAATTCTTTATATTAAACTTCCCCTGTTTAAATTACTG TGTGGTTTCTGTCTCCTGATTGGACCCAGACTGATACA46 TGATAACCTACAGGTCACATTTGGCAGGCTTCCAAATTAACCCGCC Consensus TNGGGGAGGTCTTGTGATTCATGGCNACATCCTGTCCCTGAGTA sequence for AAGAATCTTGTGAGTCCCTCAAATCTTATCGTGAGTTCCTCAAACT transposable GTTGACGTACTGATTAATACGTAACCTACTGACACTGAAAAGGA elements that CGCTGATTTGTTTCTGAATCATGAAGTTTTGCTGATTTNTTTCTGAA belong to TCATGAAGTTTTACTGATTGTCTTGCACGTAGACATTTTAGCC TGTATGTTGCAATCTGTAGCCAATGATTGTAACCTCTGTATTGTAC LTR44 CCTCCAATGAAAAAGGACAACTCCGATATGAGGAGTCCCCCTCC subfamily CTTCTCCTAAACTTTCTTATAAAAGCCTTCCAACTTGTAACAGACT CTGGAACACGCCCAACTTTGTTGGTGTGTCTTCCCGGGTCGATC CTCACATTTGGCTTCCAATAAACCTTTATCAAATTATTTCTGCCTCA ACAGCCTTAATTTCGGTCGACA47 TGTGGGGACAAGAGTGACTTTATTTTAAATGCTAATCCGCCATGTA Consensus ACTTCTGACTAACCCCGAGTCCGGGAATGCCTCCAAAATGTCTA sequence for GTTGATGTATTACTCTTTATGTAGGAACACCTATTCACTGTAAGTTT transposable CCTCCAAAACAACCCTTGATGCTGTTGCAGAAATCATAGGCTG elements that TGACGCCCGTAGCCACCTACACATTCCTTCCAGAGCACGTATACTT belong to TTTCCCCAAGATATAAGCCCTGGGTCTGGGGGGTTGCGGTGCGG AGATCTACCTGTCTTGCGGCCGCCCAAGACCACGCTTCTGTCTGTA LTR47B4 AGTTCCCCTAATAAATCACCCNANACCGACAAACTGGATTTGTC subfamily TGCCTCCTTCTTTGGTTTCTCGGCTCCTTCGGCATTTGGGGGTCGCT TTGCATATACGGCCCTTTCACGGAACA48 TGTGCCGGTTATTAAGCTATTGTCTCTCAGCTCCAAACCCACCCTT Consensus CTATACTCTGCTTTGTGATGCTGGGGCTGGGACTCGNNNNTGCA sequence for AACCACATTTCTGCTTTGCCAGCTGGCTCTCCCTGTTAGGCTCTGCC transposable AATAGGGGGCGCTAGAGGGAGACTGCAAGGGGCTGGAGGGGAG elements thatGAAGAAGGGACTTGCTCCTTCCTGTCTGCTNCTGTTTCCTGTCTGCTAttorney Docket No. 60448-717.601SEQ SequencesIDNoTCCTGTTCCTGTCAGCGTCACCCCAGCAACGCTTCTTCACCCT belong to GGCAGCAGTNGCTTCCAGTTNNTTCCAGCAGCAGCAGTTGANTCC LTR50 AGTTTGCGNNGTTCCAGTTTCCANCANTTTTTCCCAACACTCNCA subfamily GAACCAGCCTCATCGCGCCCCCTCNNNNNCCTCAGAGACACCAGC ACCAGCCGGGCAGCGCCCCCTCCTCAGAGGTCTGGGTCCCAGCTC CGCGGGGCCCCTCCTCCGAGCTCAGAGACACCAGCACCAGCCGGG CAGCGCCCCCTCCTCAGAGGTCTGAGNTCCCAGCTCCGCGGGGCC CCTCCTCCAAGCTTCTAAGTTTTAATAATTCCAACCTCTTCCCTTTT GTTCCCCCAGCCCTAGGGGNCGNTGGTAGCTGCTTCCTGCAGT TGCTACCTCCGTGATACCTTAGTGTTCTCTTTTTGCCTTTTCAGTTC TCTAATNNACAACTTTATACCTAGTTAACCCGNNTTAACAATT CTTTATATTAAATTCTCTCTGTTAAAATAACTGGTGTGGTTTCTGTC TTCTCCTGACTGGACCCTGACTGATACA49 TGTAACAGGATGTTAAANTGGAAGTTTCGGCTGAGGCACCAAGAT Consensus ACAATAGATACCANATTCCAAAGTGAGGTGCCAGACCACNATGCA sequence for GANTTTCAAAGGAGGTGGCCGAAAACCGGTTNNACGACTCTTAAA transposable CCCCTCACCCACATCGAGGGTATAAAAGGGTCGGGANGTTGGAGA elements that TGAGGGGAGATTTGTGAAGAGGATTTCTTTGGAGAGAGCTGTTGG belong to TGTGCTGTGAGTCCCACCCCACCCCCAAGGAGAGAGGAGGGGGGG TGCTCCCCCTTCACCTCAAGCCNAGNGAGAGGGGCTTCAACGGGA LTR78 CCACTCGGAGAGCTTGATATGTGTCCCCTGCAGTTTGGGGGACAC subfamily AGTGGACTGGTGTCTGACTCNCGCCTGGGAAATCTAAAGGGCGAG AGACGGGCTGGCCAGCTGCTCTGACGGCGGAGCAAAGGAGAGGT GGCTGCGCTGGGATCGGCCTGCACTCCCAGAGTTTGTCGGGGCAA AGGATGCGTGAGTGTTTCCCGTGGACCAGATGTGGGCCACGCGNG AGAGAGAGCCGGCGTGGGGTCGTCTTAGGTCCTGTCCAAGAGGGC CGCCTGGAGGGGCGAAGGGACCTCAGCAGAGAGAAGCTGGAGGT ACCGCCGGATTCCCAGGGGCTGAGGAAGGAGTAAGCGACCAGCCG GAAGAGAGATGCATTCGCCCGCGTCAAGGGAACTGCAGGTGAGAG ATCCCCAGCGATGGGGGGGGGGATCTCCGAAGAACCCACGAAAGC GCCCACGAGAGAAAGAGTCAGCTTTAAACACCTGCCAGGCCCAGA GAGCGCGAAGCCAGCTCACAGACAGTACCAGTCAAGTAAGAACTT TCCTGCTCCCCTTNCCTCTCCTCCCTCCCCNCGCTCCAACCCTGGAG GGGTCAGAAACCGCGGTTAGCAAGTGGGGGAGGAGGAGNAGGGA AAGAGAAAAAAGAAGCCACCACACCCCCTTCCCCGGCTGCAGGCT TCCNGCCTGCAGCAGGCCCGAGCTGGGGGAGGGGAGAAGCTTTAA CTTTAAATCAAGTTCGGAGTTTTGATTATTACATGGGACTGGACAT TTTAATTACTGAATTGAGACTGTGTTTTGTGACTTAAAGTGACCGT AGGACTTTTTATTACCTAAGAGTGACCAGAAAAGTCATGGGACC TGCCCGAGTTTTCATCCAGGGGCAGGGGAAGAACTANCCCCACTG AATAAATTTAAAGGGACAGTGGGAGACAAAAATAAAGTTGCTTTN TGATTACATCCCATGAGTCNTGCTTGTTCAACGTACCGGTTACA50 TGAAACCGCCTTTGCAAAGATTATGACAGTGAGAGAAATCTGACA Consensus TGGCTGACTCCATCTTGCTTCTAGCCTCACAGGCTGGCTGTCCTC sequence for GCTCATTCCTGGGCGTAGGCCAAGCTAACCNTGGGAGGAATTTAG transposable TTTATAGTTTAACTTTGAAGCAAGGATGATAATAGTCCCTCCCTA elements that AAACTAACCCCCTCCTTGCTCGGGGACCGAAACCGCCTTTGTAAGA belong to CTAATGAAAGGCCACAAGATTAGGATTATGGGAGGGGCCTGAAT TCTGCTAAGATGTAGGCATAGTTAAACGATAACCAGCCATTGTNCC LTR8B CGNNNCGNNTTTCTATAATCCCTTACTGCTCAGGAGTCATGTGG subfamily CCAGAGGTCACAAGATTTGTGACTTCCCCAATTGCTCCTATAGATA ACATCACTATTGTAGAACCTAAGATTGGTCTTTTGAGATGTTTT TCAGACTTTTGCATTCTGGCGACCGACTGACCCCACCCGGACCCGTGACTCATGACTCAACCGGTCCTGTGGCCGNNNNCGNNNCCCACCAttorney Docket No. 60448-717.601SEQ SequencesIDNoCAGAGGCGGACTCAGCGCACGAGGACCCGTTTTCCACACCCCTAT GATTTNCATCCCCAACCAATCAGCAGCACCCATTCCCTAGCCCCC TGCCCACCAAATTATCCNTGAAAAACCCTAGCCTCCGAGCCTTCGG GGAGACTGATTTGAGTAATAANCTCCAGTCCTCCCGCNTGGCCG GCCTCGCGTTAATTAAACTCTTTCTCTACTGCAATACCGCGGTCTC AGTGAATTGGTTTTGTCTGTGCAGCGGGCAGGAAGAACCCGTCG GGCGATTACA51 TGTTAGAAATTTGATCGGGGATTTCCTGTGCAGTCTGGAGCTGAGA Consensus ANAAGGAGATCATGACTTGGGCTTTGCAGCCCAAATATCTTTCC sequence for TTCCCCATCCCCCAAAATACACCCAATCAAATAAGGTTAGGATGAT transposable GGTTACCAGGCAGCTTGCAAAAGCAAGGGCATTCCACCCTCCGA elements that ATTTCTGGTCAGAGANAGTANATATGTAAAACAGAATATGCTCCA belong to TTGTTAAGCAAACACCCTNTTTATTGATAGTGGGTCAACAAGAGC ATAGGCAGGTTTAGCTATACAGACAACTAACAGAATTTGAGATGC LTR90A AGAATATTAAAGCTAAGAATCCAAGATCAATCATTCAAAATACAA subfamily GTAGATACGCAGAGAAAATATCACAGCATAAGTAGCAGTNCTAAA ACGCAAAGGGCTAGAGTCCTGCNAAGGCCTTTCCTACGCAGAAGN GCCAAAGCGGAGATTCAGGATCAACGCTGTTAAAATGCAAAATAT AATCAGGAGCAAGCNCTANCGAATCCTGCAAAGGCCTTTCTTAAT TAAGCANTTCTGANATACATNCAACTCCTGGTTATAGAAGGNNNN NNNNNNNNNNNNNNNNNNNNNNNNNNNNCCAAGGGAAAAGCGG NGAGAAAGCAGAGAGAAAGAGNAGCCGGAAAATNCCAGCTCCTT AAAAGCTCTAAACAAGGGGCGGAGACTCGCTCCTCCCTGGCCAAT CCTTGATGGCTCCGGAGAGGGCGCCCTGATTAATACTTTGTTACGT CATTAAAAGGGGTCAGCTTAAGGTAAGGTAATGGAGNTCCCATGA CCTATTGACCTTGTTACGTCATTAGAGAGGCCANCTTTGGCCCAGA AAATGGCGGATTCCTTCCCTGTGATTCACACATTACCCAGAAGCCT CTGGCTTCCTGGAATTCTTAATAAAAATTCCAAATCTCTCGGCAAT AACTTTCAAACACCACAATTTTCGCTAACA52 ACATTTTCTGGCGACGAGGATGGGATCCTGTTAAAAAGAAAGCTG Consensus GACAACAGCAGGCAGTGTAAATCCACTCTCAAGTACTACTGGTAA sequence for GCAATTGAATACGGCCTCCACCCTGGAACTTGAGCAGACCCTGTG transposable CTTAAAATGGCTGCTTTGGAGCATATTGAAGAGTTTGATGTCAGT elements that CANCCTGCTTCCTGGGATTCATATGCTGAGAGGCTTTCATTCTATC belong to TTGAAGCAAACAAAATAGAGGGCCCTGAACAGAAGCATGCTGTG CTCCTGACNGTCTGTGGGGCCCAAACATNTGCCATAATAAGGTCTC Mamgypsy2-I TCACCGTCCCTGCTTCACCTAAGACTAGGACATTTGATGAACTT subfamily GTGGGATTATTGAAGGCGCACTTCTCACCAGCACCATCAGTCATTG TTCAGAGATTTAAATTTCACAAATGGAATCAACAGCCTGGTGAG GGCATTGCTGCTTATATTGCAGAGCTGCGCCATCTGTCTCAACACT GCAATTTTGGGGATTTCTTAGATGACATGTTGCGGGATCGCCTT GTATGCGGAGTTCACGATGAAGCCCTCCAACGGCGCCTCTTGACTG AACCAAATTTGACATTTATAATGGCCCAAGAAAAGGCCCTAGCC AGTGAGACTGCATCACTACATGTCACAGAAATTAAAGGAGCAGCT TCTAATATAAATGCTGTCCATAACACGCAGGCAGAGAGCTCTTGC CAACAGGGTCAGCAGAACACAGGAAATGCNCGTTCCAGAATATCT GCAGATCAGTTCAGACATACCAACCCCTGCTCAGGCTGCGGAGGG TTACACCAACGCTCTGCTTGCAGATTCAAGGATGCGGAGTGCAGA TTCTGCAAGAGGAAGGGCCACCTTGAGAGAGTATGCCGTTCAAAA TCCATTAGAATGAAGTCCAGGAACTGTCGTAGCAGTTCACATCACC TGGCATCAGGTGATCTTGATTATTCACATGACAGTGAAGCCCAG GAATTGTATCATATTCAGAGGGTCCAGGGCAAGATGCCTCAGGAT ACTGCAGTATTTGCAACAGTACTCATAAATGGCCATGAGTGCAAGATGGAAGTCGACTCCGGTTGTGGTATATCAATAATCGGTAAAGATAttorney Docket No. 60448-717.601SEQ SequencesIDNoACCTTCCACAATATTTTCTCACAAGGCCCTTTGCCAAAGTTGTTG AGGCCACCATGCATTCTTCAAGATTACAATGATCACACAGTTGATG TTGCTGGAAGCTGTGTTGTGAATGTGCAGCGTGGCTCCTTCACG GAGAAGCTTCCACTTATCATCGCAAGGGGGCAGCGCAAAAGCCTC TTGGGAAGGAACTGGTTCACACCACTAGGAATCAGTGTCCAAGGC ATTCATACCATTAGAACAGCCCGACTACAGGAAGTTGTCAACAGA TTTCCCAAGGTATTCTCCGAGGAACTGGGAGCTTACAAGAGGGAG CCAGTGTCATTCCATCTGGATCCAGCCATTGCACCAATTCACTTGA AAGCTAGAAATGTACCTTTTGCTCTAAGGAAAAAAANTGAAGAA GAGCTTGAGCATCTAATCAAACAAGGTGCCCTCGAACCAGTTACA CATACCCGGTGGGCTATACCAATTGCGCCGGTACTAAAGCCTAAT GGTAAGGTGAGACTTTGTGGAGACTACAAGTGCACTGTGAATAAG GCACTTAAGCAGCACCCATATCCAGTGCCTGCAGTCAATCAACTC CTTGCTGTTCTTGCTGGGGAAAAGGTCTTTGCGAAACTTGACCTTG CCCAAGCTTATCAACAGCTGATCGTCAGTGATGCTACTGCAGAC GCCCAAACAATCATCACTCATCGAGGGGCATTCCGAGTTAAGCGC CTTCAGTTCGGAATTTCTGTTGCCCCTGGAATTTTCCAGTGCTTC ATGGAGACCCTGCTTTCTAGGATTCCAGGTGTGGTACCATATTTCG ATGATGTCCTGATCATGGGATCAACAGAGGATGAACTCGCGGAA AGACTTCAGGAAGTCCTACATCGTTTCGATACATCAGGTATCCGAG TGAAAAAGGAGAAATGTGAAATCGGAACTTCCAGTGTCACCTTC TTAGGCTACCGCATCAATGCTGCTGGTATTCACCCCACTCAAGATA AGGTACGTGCAATCCATGACGCGCCTACTCCAAAAACAAAGCAA GAGCTTCAAGCCTTCCTGGGGCTACTCAATTTCTACCATGTTTTTCT TCCACAAAAGGCAACCATTGCTGAGCCACTTCATCGCCTACTG GGAAAAGGCGTTCCGTGGCGTTGGACTCGCCAGCATGAGGACGCT TTCCGGAATGTCAAGCAGTTATTGACTTCCGAGTCTGTGCTAGTA CATTACGATGAACATAAACCACTGTTTCTTACCACTGACGCTTCAC CTTACGGTGCTGGAGCTGTGCTTAGCCACAAAATGCCAGATGGC ACTGAGGCACCAATTGCTTACTACTCAAGAACAATGTCATCTACAG AATGGAACTACGCACAAATTGACAAAGAAGCCCTTGCTGTTATC GCGGGAGTCAAGAAGTTCCACAACTACCTCTACGGCCGTGCCTTTA CAATTTGTACTGATCACAAGCCTCTTTGGGGACTCTTTTCTAAG GATAAGCCTACGCCCTTAATTATGTCACCACGTATGCAGCGCTGGA GTCTTTTGCTCAGTGCTTATGACTACGCGCTTGTCTACAAGCCT GGAAGAGCAATATCGAATGCTGATGCCCTGAGCCGTCTGCCACTG CAGATCCCAGATTATGTTGTGCCACTTCCACTGGAAGTTTTGATG TTAGAAGACCTCCCTGACCCACCTCTTCAGGCTGATCAAATCGCAC GATTAACTGCGTGGGATCCCAGATTGGTCCGTGTCTTAAACTGG GTGTGGAGGGGGTGTCCAGTAGAGAAACTGCCTGAGGAATTCAAG CCATTCACAAGCCATCAACATGAGTTATCTGCCCATAAAGGATGC CTTTTATGGGGAAATCGCATTGTTATTCCAGAAGGCGGTCATCACG TTATCTTGGCCACACTACATGCAGCACATCCGGGAATTGTTCGC ATGAAAGCATTGGCTAGAAGCTATGTCTGGTGGCCTGGAATTGATT CTGATATTGAAAAGACTGTAAAGGAGTGTAGCACATGCCAGGCT ACTCGGCATAACCCGCCAAAGGCACCTACTTTTCCATGGAAAGTG ACCAAGAAGCCTTGGTCAAGAATCCATATTGATTTTGCAGGACCA TTCCAGGGGAAGAACTTCTTGATTGTGGTAGACTCCTTCTCAAAAT GGCTCGAAGTGCTCCTAGTTCCATCTCAAACCTCTGCTGCAACA ATCACAGCTCTGCGCCAGTTATTTGCAACACACGGATTGCCAGACA CTATCGTTTCTGACAATGGGTCTGCATTTACCTCAGTTGAGTTT AAGGAATTTGTGGACAGGAACCTTATCCGAGCTGTCACCATCGCG CCTCATCACCCTCAAGCAAATGGTCAGGCTGAAAGGATGGTGCAGACTACTAAGGATGCCCTGAAGCGGATTGTTGGAGGAGATTGGCCAAttorney Docket No. 60448-717.601SEQ SequencesIDNoACAAGACTTGCCAGGTTTCTCATCGCTCAACATGTCACTCCATGT TCAACAACAGGAGTCAGTCCTGCTGAATTACTAATGGGGCGACGT CTCAAGACTTGCCTCGACCGTCTCCATCCAGACTTAGATGAGGAC TTACAAGACAAACAAGAATGTATTCTGGATGCTGCTCTGTCTGCAC CTACTCTTCGCTCATTTTTACCACAAGAGTTAGTCTTTGCTAGG AACTATGGAGCTGGACCAAGGTGGGTTCCTGCCACTATAATTGAG GTCACGGGGCCTGTGTCATACAAGGTCCAGAGTGCAGATGGGCCG GTGTGGCATCGCCGTGTTGATCAACTGCGAAGGCGTTCCTCCCAGG GTGACTTGACAACAGCAGAACCATTAGAAGCATCTCCTCTAGAG CCATCTGGCGTTGATTTTTCAGCTATACCTCCTGAGGACTCACCAG AGCCACAAAGTGAAGGAAGCAATAATTCTTCTCTGGCCACCGCA ACTGCTGAAGTGGAGTCACCTGGTATTTCTACACCCACTAGTATAA CACAGAGACAGCCTCGCAAAAGGGTACCCCCTTGCTGGTTAAAA GATTATGTTAGCTAAGGGGGAAGGGG53 TGTTGTCAGTACTTGGGGGCTACAGTGAGGCGTCCCCCAAGAACTT Consensus GGAAATAAGGGAAATAAGATTGCCCTCTGAGAGTTAAACTATAA sequence for AATCAACACATAATGGATCAGAGCAGAGATATGCAAAGTCACCTT transposable AAAGAGACAGAATGGCTCCCAGGCCAGCAAGACTTGACTGTAACC elements that TGATTGAATGTATTAACATATCTAAAGAAAGAATGTGTCAATCAG belong to AAGGGAGGTTGGTCAGCCATGGAAGCATAGAAAAAGGAGAGTCA CAGAGGCAAACGTTGGCAGTGCCCATCCAAGCACTGTCCAGGGGA MamRep605 GAGGGAGCCTTGGCCAACGGACTTCGAGTATTCCGGTCCCATTGG subfamily CAAGGCCATCCCTACTGTGGAGATGGATGCATCAGGCTATCTTAGC CTGATGCCATTAAACATTCGAATCATNTAACTAACTCCCCTTGTT CTGATTCCATGCTCACCAAGCAACCTTCTGATTATAATTTGGCTTC CCATGTAGGTCTGCCTACAGGGAGAGAATGCGCTGGTCATGCNG ACNCGAGTATTCTGGTCCNCGTGACAGTTATATTTCTCATTGTAAA TTAATAAATTGGCATTCTGGTTTTATACATCAGTCTCGTGAGCT TGGTTAATGTGAGTCCGCCCCTGAGAGATGGATCCGCTCTCGGTGT GCTGACAAAATCAGGTTTCTGAGCCTGCAAGGCTGAGGGCCAGA CCCTGGACCGTGGTAAATTCACCAAGGTAATGCCACCCTGTGAGG CCTCTTGGGAGACAGCCAGCCGGCCTTTCCCCTGGTGACACTCCA NTCNCCACGATGTTGCCATTGGCATTTTAAATTCTTACA54 TGTGATATTGTGATATAATAAGAAATATATATTTGGTCTCTGCCCC Consensus CGGTTCCTGGCACAGAGCTCCTAAAACCCTTGTAATTTCCTGAG sequence for CGATAGGGGTGCTAGGAGCATCTTTTGTTCTAATATTTGGTCTTTG transposable NCCCCGGTTCCTGACACAGAGCTCCTAAAACCCTTGGAATTTCC elements that TGGGTGATAGGAGCGTCTTTTGTTCTAATGAGGTGACTCTTGGCTG belong to GGGGCTCCTGGATAGCCTCAGGATGGGGGCTGGTCGCCAGAGGA ACCAACCATGTGATTAGAGGGTTGGAACTTTCAGCCCCACCCCCG MER21C ACCTCCGGGGAGGGGAGAGGGGCTGGAGATTGAGTTAATCACCAA subfamily TGGCCAATGATTTAATCAATCATGCCTACGTAATGAAGCCTCCATA AAAACCCTAAACGACGGGGTTCGGAGAGCTTCCGGGTTGGTGAA CACATNGAGGTGCCGGGAGGGTGGCGCGCCCGGAGAGGGCACGG AAGCTCCGCGCCCCTTCCCACATACCTTGCCCTATGCATCTCTTCC ATCTGGCTGTTCATCTGTATCCTTTGTAATATCCTTTATAATAAACC GGTAAACGTAAGTAAAGTGTTTCCCTGAGTTCTGTGAGCCGTT CTAGCAAATTATCGAACCCGAGGAGGGGGTCGTGGGAACCCCCGA TTTATAGCCGGTCGGTCAGAAGTACGGGTNACAACCTGGGACTTG CGACTGGCGTCTGAAGTGGGGGCAGTCTTGTGGGACTGAGCCCTT AACCTGTGGGGTCTGACGCTAACTCCAGGTAGNTAGTGTCAGAAT TGAATTGAATTGTAGGACACCCAGTTGGTGTCCGCTGGAGAATTG NTTGGTGTGTGGGAAAAACCCCACACATTTGGTGTCAGAAGTGTTGTGAGAGTAGAGAAAAACAGTTTGTTTTTTCCTACACAAttorney Docket No. 60448-717.601SEQ SequencesIDNo55 TGTTGGGGCTCAGAANACGATACCCCAAAGTATGGCGCCTTGGCA Consensus TGCTGAGTACTTTGAACTGAAGGAGATTGGAAGGCCTCAGAAGCA sequence for GCCTCAGAAGCAAAGTCTCTCTCTGACCTTCTCCCGCCCTCCTGTC transposable TCCCGCCCCCGTTCTCTCCTCCCCGAAGCGAGTCATAGAAACCA elements that GAATTCCTCTTCCCCAAGGCGGGTCATAGAAACTAGAACCCCTCTC belong to CCCCAAAGCAAGCCATAAAACCTAGAAANGTCACTCTGACCTTC CCCCGCCTTTCTGTNTNGGAGCNGGCCATAAAGAAATTCTCTGACC MER39 TNCCTTGTCTGANAGTAGGTCATAAGACCCTCATTCCAGAAGGG subfamily GTCCTGCCCTATACCCGGGAGGAAGGAATGCTACACAGAGAGGCC AAGAAGAATCTGAACAGACAGGCCTTGCTGGGTTTCCCCNCTCAG TTTATTACCATTAGATCATACCCCTTTTGTCCAATCACATTTCTNCA CGACTGTCCATTCTTCATCGAACCTAAGCATAAAAATANAGTT TTCCCTGNGTCTTTGGGTCTTCATTTCTGAAGGCTCCCGTGTCACGT AAAACTTTGATTAAATAAATTTGTTATGCTTTTCTCTTGTTAA TCTGTCTTTTGTTATAGGGGTGTCGGCCGTGANCCTTGCGATGGGT AGGAAAGGTATCACACCTTTCTNCCCCTACA56 TGTCAGAGGCGTTTGAACCAGAGCGACTCCATCTTGAATAGGGGC Consensus TGGGTAAAATAAGGCTGAGACCTACTGGGCTGCATTCCCAGGAGG sequence for TTAGGCATTCTNAGTCACAGGATGAGATAGGAGGTCGGCACAAGA transposable TACAGGTCACAAAGACCTTGCTGATAAAACAGGNTGCGGTAAAGA elements that AGCCGGCCAAAACCCACCAAAACCAAGATGGCGACGAAAGTGAC belong to CTCTGGTCGTCCTCACTGCTCATTATACGCTAATTATAATGCATTA GCATGCTAAAAGACACTCCCACCAGCGCCATGACAGTTTACAAAT MER41B GCCATGGCAACGTCAGGAAGTTACCCTATATGGTCTAAAAAGGGG subfamily AGGAACCCTCAGTTCCGGGAATTGCCCACCCCTTTCCCGGAAAACT CATGAATAATCCACCCCTTGTTTAGCATATAATCAAGAAATAAC CATAAGNATAGNCAGCCAGCAGCCCACGCCGCTGCTCTGCCTATG GAGTAGCCATTCTTTTATTCCTTTACTTTCTTAATAAACTTGCTT TCACTTTACTCTATGGACTCGCCCCGAATTCTTTCTTGCGCGAGATC CAAGAACCCTCTCTTGGGGTCTGGATCGGGACCCCTTTCCGGT AACA57 TGAGACCCTGCTTGNGACACATGTGAAAAATGCAGGGGAAAACCA Consensus GTCCCCTGTGGAGTGTGAAAATAATTAAGTGGCAGGCAATTAGAC sequence for TGAGGTGGCTCTAGTGCCCTGGGTTCCTACTTAAAAAAAAATCTAA transposable CTCAAATGCATTTTTTGTAAATTACTACNTTAGGGGAAAACAAA elements that ATTCAGGCTTAACCAACCATAAACCGCCAATTAANCTCTGATTACA belong to TAACCAGGAAATTTCCACCTGGATNGTACAAATNAAGAAACTAC GTAACTGTACCTAACCAATTATTGAATTTGGTTTGCTTCNTCATGC MER57E3 ACCTTATAAAAGCCTTTCCTTCAAGCCCCTCCCGTGGACCACAA subfamily ACTACAAACCATAGCTGGGTGCTCTACGATTCNTGAATCACTCTTT GATTAAATTCTTTAATATTTTTGCGGTGACTCCCATAAATTTTT AACAGGAGAAAGGAGGGACTGGGGACCCCACGGACCA58 TGAGGTAGGAGACCGGCAGGACTTGTTTTCTGGTCACAACCCTGCT Consensus GACCAAAACAGGATCTGGTCCAGACAGGATAAAGTGAAGAAACC sequence for GGCAGGAACCAGCAGATGGCGACGAAAGCGATCCCTAGCTGCCCT transposable CATTGCTCATTAGCATAAGACACTCCCACCAGCGCCATGACAGTT elements that TACAAATGCCATGGCAACGACCCGGAAGTTACCACCCCTTTCCATG belong to GCAACGACCCGGAAGTTACCGCCCCTTTCCTAGAAAGTTCTAAA TAACCCGCCCCTCAATTTGCATTGACCCGCCCCTTAATTTGCATGT MER66C AATTGAAAGTGGGTNTAAGTGAGTATAAATACAGTTGCCAAGAG subfamily CCCATACGTTGCCGACTCTGGGCGCACTGCCTATGAGTTAGCCCTG CTCCGCAAGGAGCAGTACCGTTCAATAAAAGATTGCTGTCTAACACCACCGGCTCGCCCTTGAATTCTTTCCTGGGCGAAGCCAAGAACCAttorney Docket No. 60448-717.601SEQ SequencesIDNoCTCCCGGGCTAAGCCCCAATTTTGGGGCTCGCCTGTCCTGCATC ATCTGGCTACCATCA59 TGAGGTAGGAGATCAGCAGGACTTGTTTTCCGAGCACCGGTCACG Consensus ACCCTGCTGATCAAAACAGGATGTAGCAAAGAAACCGGCCAAAAC sequence for CAGCTAGGACCAGGAATTATAATGCATTNGCATAAGACACTCCCA transposable CCAGCGCCATGACAGTTTACAAATGCCATGGCAACGACCCGGAAG elements that TTACCTTATATGGTTCCGGGAACTCCCCGCCCCTTTTCCAGAAAGT belong to TCGTGAATAACCCGCCCCTTATTTAGCATATAATTAAGAGTAGG TATAAATATAGCTAGCCAGCAATCCACGAGTGCTACTCTGGGCCG MER66D CTCTGCCTATGGGGTAGCCCTGCTCTGTCTATGGAGCAGCCATTT subfamily TGCTGTACACTGTTGCTCTAATAAACTTGCTTTCTTTCACTGTCGGC TCGCTCTTGAATTCTTTCCTGNGCGAAGCCAAGAACCCTCCCG GGCTGAGCCCCAATTTTGGGGTTCGCCTGCATCA60 TGTGCAGAAAAGAGTTAACATAGCAGGCCTGAGACTGCTATCCTT Consensus AGAAAGGCCTGCTTGCAAGGTTGGCCCTTGGCTGGCGTCTGGGAA sequence for CTTGGATTTCGGGAGGGTTCCCACCATTCCCGNAACTGATAAGAGT transposable GGCTCACTGTGCCTAAACTGTTTGTACAAACAATGTGGTTTATG elements that CTGAACACCTGCTTTCCTTCTGGGAGTCTGGAATTTTGGTACGTGC belong to TAGGCAGAGGGTGCCTACGTGACCAGCCCCCAATAAAAACCCTG GGCACTGAGTCTCTAATGAGCTTCCCTGGTAGACAACATTTCACAC MER68 GTGTTGTCACAACTCGTTGCTGGAGGAATTAAGCGCGTCCTGTG subfamily TGACTCCACTGGGAGAGGACTCTTGGAAGCTTGCGCCTGGTTTCCT CCGGACTTCGCCCCATGCGCCTTTTCCCTTTGCTGATTTTGCTT TGTATCCTTTCGCTGTAATAAATCATAGCCGTGAGTACGACTATAT GCTGAGTCCTGTGAGTCCTCCTAGCGAATCACCGAACCTGGGGG TGGTCTTGGGGACCCCCGACACA61 TGTGTAGTAAAGAATTTAACCTTGCCCAAAGAGAGGTCTGGCCTTT Consensus GCCCTCGGCTCCTGGGAGGTAATCTCTAAGCCCTTGGAATGTCN sequence for TGCCTGATAGGAGTGTCTTTGTTTGCCTGGGGGCCTTGGGCCACGC transposable CGGATAGTCTAACAATGTGATTTAGGGTGGGGGCTGGCCACGCC elements that AGAAAGACCAACNATGTGATTTAGGGTGGGGGCTTTGGGTCACGC belong to GGTATCAGCCCGACTCCGGAGGGNCTGGAGACTGAGNTCAGCCAC GTGGGCAATCAATCAATCATGCCTACGTGATGGAGCCCCAATAAA MER77B AACTCTGGACACCGAGGCTCGGGTGAGCTTCCCTGGTTGGCAATA subfamily CTCCGTGCGTATTGTCACACATCGATGCCGGGAGAGTAACGCTGTC CCTGACTCCACGGGGAGAGGACAACTGGAAGCTCCGCGTTTGGA ACCCTCCCGGACTCTGCCCTATGTACCGCGCGCCTCTTCCCTTGGC TGATTTTAATCTGTATCCTTTCCCTGTAATAAACCGTAACCGTG AGTATAACAGCTTTCAGTGAGTTCTNCGTGAGTCCTTCTAGCGAAT TATCGAACCTGAGGGTGGTTTTGGGAACCCCCCGAACTTGCAGT TGGTGTCAGAAGTGAGGGCGGTCTTGTGTGGACTGTGTCCCTCTAA CTTTGCAGTTGGCTAACTTTCACA62 GAAATTGGTACCGAGAGTGGGGGTGCTGCTATAACAAATACCTAA Consensus AAATGTGGAAGCGGCTTTGGAACTGGGTAATGGGTAGAGGCTGGA sequence for AGAGTTTNGAGGTGCATGCTAGAAAAAGCCTANATTGCCGTGAAC transposable GGANCGTTAAGGGCGATTCTGGTGAGGGCTCAGAAGAAGAGGAG elements that AGCTGTAGAGAAAGCCTCAATCTTCTTAGAGATTACCTAAGTGGTC belong to GTGANCAGAATGTTGGTAGAAATATGGACGGTAAAGGCCATTCTG ATGAGGTCTCAGACGGAAATGAGGAACATGTTATTGGAAACTGGA MLT-int GGAAAGGCCATCCTTGTTATAAAGTGGCAAAGAACTTGGCTGAAT subfamily TGTGTCCGTGTCCTAGNGCTTTGTGGAAGGCAGAACTTANGAGCG ATGAANTAGGATATTTGGCGGAAGAAATNTCTAAGCAAAGTGTTG AGGGTGCNGCGTGGCTTCTCTTGACTGCTTATAGTAAAATGCGAGAAGAGAGAAATGANTTAAAGACGGAATTTATAATCAAAAGGGAAGAttorney Docket No. 60448-717.601SEQ SequencesIDNoCAGAACNTAAAGATTTGGAAAATTCTCAGCCTGGCCATGTTGNAA AGAATGAAAAAGCGTGTTCGGGAGAGAANACCAAGGGTGTGGCC AAGCGACCGTTTGATAAGGAGATTAGTATGGATAGAAGGAAGCCA GGTGCTATTCATCAAGACAATGGAAGAATGACCCCGAAGGCATTT CGGAGATCTTCGAGGCTGCCCCTCCCATCACAGGCCCAGAGTGCN AGGGCCTNGAGGGCAGAACGGTTTCAAGGGCAGGNNCCANTCCCC ACTGCCCAGNGCCGCCTCAGTCTGCTCCCCGTCTTCGGCCGCCCGN NCAGCTGTGGCTCAAGCGGGCCCAGGTGCGGCTCGGGCCGCCGCT CCGGAAGGCACAAGCCGTAAACCTTGGCGGCGTCCACGTGGTGCT AACTCTGCAGGCGCGCAGAGTGCANGAGCTGTGGGGGCATGGCTN CCTCCACCTAGATTTCAAAGATGCGAGACCTGGGGCCCAGGCAGA GANCTCGCGGGGCAGGGCCACCGCAGAGAGCCCCCACTAGGGCA ATGCCCAGTGGAGCCGTGGGGTCGGGNCTGCAGAGAGCCCCCACT AGGGCAATGCCTAGTGGAGCCGTGGGGGCGGGGCCGCCCCCGAGA CCCCAGAACTGTAGAGCCACCAGCGTGCAACNCCAGCCTGGGAGA GCCGCAGGCACGNGACTCCAACCCGTGAGAGCTGCCGCGTGGGCT GCGCCCAGCAAAGCCATGGGGGCGGGGCTGCCCGGGGCCTTGGGG GCCCAACCCCCGCCCCAGTGTGTCCGGAAGGCGGGACATGGAGTC AAAGAAGATTATTCTCGAGCCTTAAGATTTAATGTTGTTTGCCCTG TTGGGTTTTGGACTTACTTGGGACCTGTTACCCCTTTCTTCTTTC CTATTTCTCCCTTTTGGAATGGGAATGTCTATCCTATGCCTGTCCCA CCATTGTATTTTGGAAGCACATAACTTGTTTGATTTCACAGGC TCACAGCTGGAGAGGAATTTTGCCTCAGGATGAATCGTACCTTGA GTCTCACCCATATCTGATTTAGATGATATTTAGATGAGACTTTGG ACTTTAGACTTTNGAGTTGATGCTGGAACGAGTTAAGACTTTNGGG GCTATTGGGATGGAATGAATGTATTTTGCATGTGAGAAGGACAT GAATTTTGGGGGGCCAGGGGCGGAA63 TGCTATGGACTGAATGTTTGTGTCCCCCCAAAATTCATATGTTGAA Consensus GCCCTAACCCCCAATGTGATGGTATTTGGAGGTGGGGCCTTTGG sequence for GAGGTAATTAGGNTTAGATGAGGTCATGAGGGTGGGGCCCTCATG transposable ATGGGATTAGTGCCCTTATAAAAGAGACACCAGAGAGCTCTCTTN elements that CCCCTTCCGCCATGTGAGGACACAGCGAGAAGGCGCCGTCTGCAA belong to GCCAGGAAGAGAGCCCTCACCAGAAACCGAATCTGCCGGCACCTT GATCTTGGACTTCCCAGCCTCCAGAACTGTGAGAAATAAATTTCTG MLT1A TTGTTTAAGCCACCCAGTCTATGGTATTTTGTTATGGCAGCCCG subfamily AGCNGACTAAGACA64 TGCTATGGTCTGAATGTTTGTGTCCCCCCAAAATTCATATGTTGAA Consensus ACCTAACCCCCAANGTGATGGTATTAGGAGGTGGGGCCTTTGGG sequence for AGGTGATTAGGTCATGAGGGCGGAGCCCTCATGAATGGGATTAGT transposable GCCCTTATAAAAGAGGCCCCAGAGAGCTCCCTCGCCCCTTCCGCC elements that ATGTGAGGACACAGCGAGAAGGCGCCGTCTATGAACCAGGAAGC belong to GGGCCCTCACCAGACACCGAATCTGCCGGCGCCTTGATCTTGGACT TCCCAGCCTCCAGAACTGTGAGAAATAAATTTCTGTTGTTTATAAG MLT1A0 CCACCCAGTCTATGGTATTTTGTTATAGCAGCCCGAACGGACTA subfamily AGACA65 TGCTATGGTTTGAATGTTTGTGTCCCCTCCAAAATTCATGTGTTGA Consensus AACTTAATCCCCAATGCGATAGTATTAAGAGGTGGGGCCTTTAG sequence for GAGGTGATTAGGTCATGAGGGCTCCGCCCTCATGAATGGGATTAG transposable TGCCCTTATAAAAGGGGCTTGAGGGAGCGAGTTCGGCCCTTCTTG elements that CCCTTCCGCTCTTCCGCCATGTGAGGACACAGCGTTCCTCCCCTCC belong to GGAGGATGCAGCAACAAGGCGCCATCTTGGAAGCAGAGAGCAGG CCCTCACCAGACACCGAACCTGCCGGCGCCTTGATCTTGGACTTCC MLT1A1 CAGCCTCCAGAACTGTGAGAAATAAATTTCTGTTCTTTATAAAT subfamilyAttorney Docket No. 60448-717.601SEQ SequencesIDNoTACCCAGTCTCAGGTATTTTGTTATAGCAGCACAAACGGACTAAGA CA66 TGTTATGGGCTGAATTGTGTCCCCCCAAAATTCATATGTTGAAGTC Consensus CTAACCCCCAGTACCTCAGAATGTGACTGTATTTGGAGATAGGG sequence for CCTTTAAAGAGGTAATTAAGTTAAAATGAGGTCATTAGGGTGGGC transposable CCTAATCCAATATGACTGGTGTCCTTATAAGAAGAGGAGATTAGG elements that ACACAGACACGCACAGAGGGAAGACCATGTGAGGACACAGGGAG belong to AAGGCGGCCATCTGCAAGCCAAGGAGAGAGGCCTCAGAAGAAAC CAACCCTGCCGACACCTTGATCTCGGACTTCCAGCCTCCAGAACTG MLT1B TGAGAAAATAAATTTCTGTTGTTTAAGCCACCCAGTCTGTGGTACT subfamily TTGTTATGGCAGCCCTAGCAAACTAATACA67 TGTTATGGGTTGAATTGTGTCCCCCCAAAATTCATATGTTGAAGTC Consensus CTAACCCCCAGTACCTCAGAATGTGACCTTATTTGGAAATAGGG sequence for TCNTTGCAGATGTAATTAGTTAAGATGAGGTCATACTGGAGTAGG transposable GTGGGCCCCTAATCCAATATGACTGGTGTCCTTATAAAAAGGGGA elements that AATTTGGACACAGACACGCACACAGGGAGAACGCCATGTGAAGAT belong to GAAGGCAGAGATCGGGGTGATGCNTCTACAAGCCAAGGAACGCC AAAGATTGCCAGCAAACCACCAGAAGCTAGGAGAGAGGCATGGA MLT1C ACAGATTCTCCCTCACAGCCCTCAGAAGGAACCAACCCTGCCGAC subfamily ACCTTGATCTCGGACTTCTAGCCTCCAGAACTGTGAGACAATAAAT TTCTGTTGTTTAAGCCACCCAGTTTGTGGTACTTTGTTACGGCAGC CCTAGNAAACTAATACA68 TGTTGTGGGTTGAATTGTGTCCCCCAAAAAGATATGTTCAAGTCCT Consensus AACCCCCGGNACCTGTGAATGTGACCTTATTTGGAAATAGGGTC sequence for TTTGCAGATGTAATCAAGTTAAGATGAGGTCATACTGGATTAGGGT transposable GGGCCCTAATCCAATGACTGGTGTCCTTATAAGAAGAGGGAAAT elements that NTGGACACAGAGACACACAGGGAGAAGGCCATGTGAAGACGGAG belong to GCAGAGATTGGAGTGATGCGGCTACAAGCCAAGGAACGCCAAGG ATTGCCGGCAACCACCAGAAGCTAGGAAGAGGCAAGGAAGGATT MLT1C2 CTCCCCTAGAGCCTTCAGAGGGAGCACGGCCCTGCCGACACCTTG subfamily ATTTCGGACTTCTGGCCTCCAGAACTGTGAGAGAATAAATTTCTGT TGTTTTAAGCCACCCAGTTTGTGGTANTTTGTTACGGCAGCCCTAG GAAACTAATACA69 TGTGGTAGGCAGAATAATGGCCCCCCAAAGATGTCCACGTCCTAA Consensus TCCCCGGAACCTGTGAATATGTTACCTTACATGGCAAAAGGGACT sequence for TTGCAGATGTGATTAAGTTAAGGATCTTGAGATGGGGAGATTATCC transposable TGGATTATCCGGGTGGGCCCAATGTAATCACAAGGGTCCTTATA elements that AGAGGGAGGCAGGAGGGTCAGAGTCAGAGAAGGAGATGTGACGA belong to CGGAAGCAGAGGTCGGAGTGACGACGTTGCTGGCTTTGAAGATGG AGGAAGGGGCCACGAGCCAAGGAATGCGGGCGGCCTCTAGAAGC MLT1D TGGAAAAGGCAAGGAAACGGATTCTCCCCTAGAGCCTCCAGAAGG subfamily AACGCAGCCCTGCCGACACCTTGATTTTAGCCCAGTGAGACCCATT TCGGACTTCTGACCTCCAGAACTGTAAGATAATAAATTTGTGTTGT TTTAAGCCACTAAGTTTGTGGTAATTTGTTACAGCAGCAATAGGAA ACTAATACA70 TGTGGTAGGCAGAATTCTAAGATGGCCCCCAAGATTCCCGCCCCCT Consensus GGTGTACACGCCCTGTATAATCCCCTCCCCTTGAGTGTGGGCGG sequence for GACCTGTGAATATGATGGGATNTCACTCCCGTGATTAGGTTACGTT transposable ATATGGCAAAGGTGAAGGGATTTTGCAGATGTAATTAAGGTCCC elements that TAATCAGTTGACTTTGAGTTAATCAAAAGGGAGATTATCCTGGGTG belong to GGCCTGACCTAATCAGGTGAGCCCTTTAAAAGAGGGTCTAGAGG TCAGAGACGGAAGAAGTCAGAGAGATTCGAAGCAGCAGAGACGC MLT1E TCTCCTGCTGGCCTTGAAGAAGCAAACTGCCATGTTGTGGAGAGG subfamilyGCCACGTGGCAGGGAACGGCGGGCGGCCTCTAGGAGCTGAGGGCCAttorney Docket No. 60448-717.601SEQ SequencesIDNoTCAGTCCTACAACCGCAAGGAACTGAATTCTGCCAACAACCAGTG AGCTTGGAAGAGGACCCCGAGCCTCAGATGAGACCGCAGCCCCGG CCGACACCTTGATTTCAGCCTNGTGAGACCCTGAGCAGAGGACCC AGCTAAGCCGTGCCCGGACTCCTGACCCACGGAAACTGTGAGATA ATAAATGTGTGTTGTTTTAAGCCGCTAAGTTTGTGGTAATTTGTTA CGCAGCAATAGAAAACTAATACA71 TGTGGTAGGCAGAATTCTAAGATGGCCCCCAAGATTCCCACCCCCT Consensus GGTGTACATGCCCTGTATAATCCCCTCCCCTTGAGTGTGGGCGG sequence for GACCTGTGAATATGATGGGATATCACTCCTGTGATTAGGTTACGTT transposable ATATGGCAAAGGTGAAGGGATTTTGCAGATGTAATTAAGGTCCC elements that TAATCAGTTGACTTTGAGTTAATCAAAAGGGAGATTATCCTGGGTG belong to GGCCTGACCTAATCAGGTGAGCCCTTTAAAAGAGGGTCTGGAGG TCTTTCTGAAGAAGTCAGAGAGATTCGAAGCAGCAGAGATGCTCT MLT1E1 CCTGCTGGCCTTGAAGAAGCAAGCTGCCATGTTGTGGAGAGGGCC subfamily ACGTGGCAGGGAACNGCGGGCGGCCTCTAGGAGCTGAGGGCCTCA GTCCTACAGCCGCAAGGAANTGAATTCTGCCAACAACCTGAGTGA GCTTGGAAGNGGACCCTGAGCCTCCAGATGAGAACGCAGCCCCGG CCGACACCTTGATTNCAGCCTTGTGAGACCCTGAGCAGAGGACCC AGCTAAGCCGTGCCCGGACTCCTGACCCACGGAAACTGTGAGATA ATAAATGTGTGTTGTTTTAAGCCGCTAAGTTTGTGGTAATTTGTT ACGCAGCAATAGAAAACTAATACA72 TGTGGTAGGCAGAATTCTAAGATGGCCCCCAAGATTCCCGCCCCCT Consensus GGTGTACACGCCCTGTATAATCCCCTCCCCTTGAGTGTGGGCGG sequence for GACCTGTGAATATGATGGGATATCACTCCCGTGATTAGGTTACATT transposable ATATGGCAAAGGTGAAGGGATTTTGCAGATGTAATTAAGGTCCC elements that TAATCAGTTGACTTTGAGTTAATCAAAAGGGAGATTATCCTGGGTG belong to GGCCTGACCTAATCAGGTGAGCCCTTAAAAGAGGCATGGGCCCT CCAGAGAGAAGAACAGAGAGATTCTCCTGCTGGCCTTGAAGAAGC MLT1E1A AAGCTGCCATGTTGTGAGAGGGCCTATGGAGAGGGCCACGTGGCA subfamily AGGANCTGNGGGCGGCCTCTAGGAGCTGAGAGCGGCCCCCGGCCG ACAGCCAGCAAGAAAACGGGGACCTCAGTCCTACAGCCGCAAGG AANTGAATTCTGCCAACAACCTGAATGAGCTTGGAAGNGGACCCT AAGCCTCAGATGAGAACGCAGCCCTAGCCGACACCTTGATTNCAG CCTTGTGAGACCCTGAGCAGAGGACCCAGCTAAGCCGTGCCCGGA CTCCTGACCCACAGAAACTGTGAGATAATAAATGTGTGTTGTTTTA AGCCGCTAAGTTTGTGGTAATTTGTTACGCAGCAATAGAAAACTA ATACA73 TGTGGTAGGCAGAATGGCCCCCCAAAGATGTCCACGCCCTAATCC Consensus CCGGAACCTGTGAATATGTTACGTTACATGGCAAAAGGGACTTTG sequence for CAGATGTAATTAAGGTTACGGACCTTAAAATAGGGAGATTATCCT transposable GGATTATCCGGGTGGGCCCAATCTAATCACATGAGCCCTTAAAAG elements that CAGAGAACTTTCTCCGGCTGGAGTCAGAGAGATGCGGCAGAAGGG belong to GAAGTCAGAGAGATTCGAAGCGTGAGAAGGACTCGACGCGCCGTT GCTGGCTTTGAAGATGGAGGGGGCCACGTGNCAAGGAATGCGGGC MLT1E2 GGCCTCTAGGAGCTGAGAGCGGCCCCCGGCTGACAGCCAGCAAGG subfamily AAACGGGGACCTCAGTCCTACAACCGCAAGGAACTGAATTCTGCC AACAACCTGAATGAGCTTGGAAGCGGATTCTTCCCCAGAGCCTCC AGANAAGAGCNCAGCCCNGCCGACACCTTGATTTCGGCCTTGTGA GACCCTGAGCAGAGAANCCAGCCGAGCCCACCCGGACTTCTGACC TACAGAACTGTGAGATAATAAATNTGTGTTGTTTTAAGCCGCTAAG TTTGTGGTAATTTGTTACGGCAGCAATAGAAAACTAATACA74 TGTGGTAGGCAGAATTCTAAGATGGCCCCCAAGATTCCCGGCCCCT Consensus GGTGTACACACACCTTCTCCCAGTTATTCAATCAAACACTAATC sequence forTAGGTGCTGCTGTGAAGGGATTTTGCAGATGTAATTAAGGTCCCAAAttorney Docket No. 60448-717.601SEQ SequencesIDNoATCAGTTGACCTTAAGATAGGGAGATTATCCTGGGTGGGCCTGA transposable CCTAATCACGTGAGCCCTTAAAAGGGACTGGGCTCTTCCTGGAGA elements that AAGAGATTCGAAGCGTGAGAGGGATTCGACGCGAGGGAGATTCTC belong to CGTTGCTGGCTTTGAAGATGGAGGGGGCCACGTGGCAAGGAATGC MLT1E3 GGGCGGCCTCTAGGAGCTGAGAGCGGCCCCCGGCTGACAGCCAGC subfamily AAGGAAACGGGGACCTCAGTCCTACAACCGCAAGGAACTGAATTC TGCCAACAACCTGAATGAGCTTGGAAGCGGACCCTGAGCTCCAGA TGAGAACNCAGCCCGGCCGACACCTTGATTTCAGCCTTGTGAGAC CCTGAGCAGAGAACCCAGCCACGCCGTGCCCGGACTTCTGACCTA CAGAACTGTGAGCTAATAAATGGGTGTTGTTTTAAGCCGCTAAGTT TGTGGTAATTTGTTACGCAGCAATAGAAAACTAATACA75 TGTGGTAGCCAGCCTCCAAGATGGCCCCCAATGATCCCCGCCTCCT Consensus GGTATTCACGCCCTTGTGTAGTCCCCTCCCACACTGAATAGGGC sequence for TGGCCTGTGTGACCAATAGGATATNGCGGAAGTGACGGTGTGTGA transposable CTTCCGAGGCTAGGTCATAAAAGACATTGCGGCTTCCGCCTTGCT elements that CTCTCTTGGATCACTCGCTCTGGGGGAAGCCAGCTGCCATGTCGTG belong to AGGACACTCAAGCAGCCCTGTGGAGAGGCCCACGTGGCGAGGAA CTGAGGCCTCCTGCCAACAGCCAGCACCAACTTGCCAGCCATGTG MLT1F AGTGAGCCATCTTGGAAGCGGATCCTCCAGCCCCAGTCAAGCCTT subfamily CAGATGACTGCAGCCCCGGCCGACATCTTGACTGCAACCTCATGA GAGACCCTGAGCCAGAACCACCCAGCTAAGCCGCTCCCGAATTCC TGACCCACAGAAACTGTGTGAGATAATAAATGTTTATTGTTGTTTT AAGCCGCTAAGTTTTGGGGTAATTTGTTACGCAGCAATAGATAA CTAATACA76 GATTTTGGTACCTGGAAGTGGGGTGCTGCCGTAACAAATACCTAA Consensus AAATGTGGGAGTGGCTTTGGAACCGGGCAGTGGGCGGAAGCTGGA sequence for AGGATTTTGAGGAGCGTGNTAGNGAAAGCCTAAANTGCCTTGAAC transposable AGACTGTTAGTAGAAATCTGGACTTTGAGGANGCTGCCGGTGAGG elements that GCTCAAAGGGAAGTGAGGAANATGTTATTGGAAACTGGAGGAAA belong to GGGGATCCTTGTTATGTAGTGGCAGAAAGCTTAGCAANACTGTCG CCTGCAGTTATGTGGAAAGTAGAAAATGTANCTAATGAACTNGGT MLTIF-int GATCTAGCTAAGGAGATTTCCAAGCAAAGTGTTGAAGGTGCCGCC subfamily TGGTTTCTTCTTGCTGCTTATAGTAAAATGCGAGAGGAGAGAGATA AACTGAGGGAAGAACTGTTAAACAAAAAGGAGCCAGGACTTGAT GGTTTTGAAAATTCTCAGCCTCTCCAGATGGCAAANGATGCTAAA ATTAAGAAATGGCTTCCGAGCAAAGATCAAATCCAGGGCACTGTC AGGAAAACATGGTCTAAAGATGAAGCCGAGGGTGTGACTGTAAAA TCCTTTGTTAAGACCTCAGAAAGATCAAAGGTGGTGCCTCAGAGT ACTATTCAGTCANACAAAAGGCCCTTTAAAGAGATTAAGGGTGTG CCTCACAGATCCTCTCAATCAAACAATAGGGCTTCTAAGAAGCTTA AGGGCGTTGTCCCTCAGCCGTCTCAGCAGAAGCCCAAGGTAGAGA AGGGCTTATCTCGAAGAGATTTGTGGGTGTGGCTTTTGTCTAATG GAGTGAACCCCAGTAAGATTCACAGGAGACCCACAAAGTTTTTAA GAGAATTATATCAGCAGAAACACTGCCAGCTTGGACTGAAAGGGA CAGAGACAGTACAAAATGAAAAGAGGCCTTTGGACCCCCAAANTT CTACNGGCAGGAAGCAGGCTGANAAAACTACTCAGCTGCAAACAC GTGCTACCTTTCATGAAAAAGGAAGGATGACTCAGAGGGCGGAAC CAAGAGCCCAGAGGGCGGAGCCAAGAGCCACGGAGAATTATTCCC AGGCCTTGAGACCTAATCAAGGAACTTCCAACATTTGCCCGGCTG GATTTCAGAATTGCTATGGACCAGTGACTCCTTTGTGCCTCCCAT TTTCCCCCTTTTTGAACGGGAATGTCTATAGCGGTTATCCTATGCCT GTCCCACCATTGTATGTTGGGTGTGTNGGGGGCAGATAACTTG TCTCTTTAGTTTCACAGGTCTNCAGATCGAGAGGAACTGTACTCGAGGAGCTGTACTTAAGGAACTACACCCGAGGAGCCTCATCCACACAttorney Docket No. 60448-717.601SEQ SequencesIDNoCTGGACCTGATTTAGATGATGAGATTCTGGACTTTGAGCTGATGCT GTAATGGGATGAGACTTTTGGGGATCTTGGGAGGGGGGTGAGTG TATTTTGCATGTGGGAGGGACGTGAATCATTGGGGGCCAGAGGGC AGAC77 TGTGGTGGTTTTAAAATATGTCCACAAATTCTTTGATACTCCTCCCT Consensus TCAAGAGGTGGAGCCTAATTCCCCTCCCCTTGAGTGTGGGCTG sequence for GACTTAGTGACTCGCTTCTAACGAATAGAATATGGCGGAAGTGAC transposable GGTGTGTGACTTCCGAGACTAGGTCATAAAAGGCATTGCGGCTTC elements that CTCCTTGCTCTCTCTCTTGGATCACTCGCTCTGGGGGAAGCCAGCT belong to GCCATGTCGTGAGGACACTCAAGCAGCCCTATGGAGAGGCCCAC GTGGCGAGGAACTGAGGCCTCCTGCCAACAGCCAGCAAGGAACTG MLT1F1 AGGCCTCCTGCCAACAGCCATGTGAGTGAGCCATCTTGGAAGCGG subfamily ATCCTCCAGCCCCAGTCAAGCCTTCAGATGACTGCAGCCCCGGCC GACATCTTGACTGCAACCTCATGAGAGACCCTGAGCCAGAACCAC CCAGCTAAGCCGCTCCCGAATTCCTGACCCACAGAAACTGTGTGA GATAATAAATGTTTGTTGTTTTAAGCCGCTAAGTTTTGGGGTAAT TTGTTACGCAGCAATAGATAACTAATACA78 TGTGGTAGGCAGCCTCTAAGATGGCCCCCAATGATCCCCGCCTCCT Consensus GGTATTCACGCCCTTGTGTAATCCCCTCCCCTTGAGTGTGGGCT sequence for GGACCTAGTGACTCGCTTCTAACGAATAGAATACGGCAAAAGTGA transposable TGGGATGTCACTTCCGAGATTAGGTTACAAAAAGACTGTGGCTTC elements that CGTCTTGCGCGCCCTCTCTTGCTCTCTCGCTTGCTCGCTCTGANGGA belong to AGCNAGCTGCCATGTTGTGAGCTGCCCTATGGAGAGGCCCACG TGGCAAGGAACTGAGGGCGGCCTCCGGCCAACAGCCAGCGAGGA MLT1F2 ACTGAGNCCTGCCAACAACCACGTGAGTGAGCTTGGAAGCGGATC subfamily CTCCCCCAGTCGAGCCTTNAGATGACCGCAGCCCCGGCCGACACC TTGATTGCAGCCTCGTGAGAGACCCTGAGCCAGAGGCACCCAGCT AAGCCGCGCCCGGATTCCTGACCCACAGAAACTGTGAGATAATAA ATGTNTGTTGTTTTAAGCCGCTAAGTTTTGGGGTAATTTGTTACGC AGCAATAGATAACTAATACA79 TGTGGCGGTTTTTAAAACATGGCCGCAAATTCTTTGACACTCCTCC Consensus CATCGAGAGGTGGGGTCTATGTCCCCTCCCCTTGAATCTGGGCG sequence for GGCTTGTGACTGCTTCGACCAATAGAGTACGGCGGAAGTGACGCT transposable GTGTGACTTCCGAGGCTAGGTCATAAAAGGCCATGCAGCTTCCGC elements that CTTGTTCGCTGGAACACTCGCTCTTGGAGCCCTGAGCCGCCATGTA belong to AGAAGTCCGACTACCCTGAGGCCGCCATGCTGTGAGGAAGCCCA AGCCACATGGAGAGGCCACGTGTAGGCGCTCCGGTCGACAGTCCC MLT1G AGCTGAGCCCAGCCTTCGAGTCATCCCAGCCCAGGCGCCAGACAT subfamily GTGAGTGAAGAAGCCTCCAGATGATTCCAGCCCCCAGCCGTTCGA GTCACCCCCAGCCGTTCGAGTCTTCCCAGCTGAGGCCCCAGACAT CGTGGAGCAGAGACAAGCCATCCCCGCTGTGCCCTGTCCGAATTC CTGACCCACAGAATCCGTGAGCATAATAAAATGGTTGTTGTTTTA NGCCACTAAGTTTTGGGGTGGTTTGTTACGCAGCAATAGATAACTG GAACA80 TGTGGCAGATTGTATTTTCCAAAGATGGCCGCAACAATATCTCCCA Consensus TCCCACATGCTCTTCTTACAATGTGACNTTGACACTCCTCCCAT sequence for CGAGAGGTGGGGTCTATGTTCCCTCCCCTTGAATCTGGGCGGGCCT transposable TTGTGACTGCCTCGACCAATAGAATGCGGCGGAAGTGACGCTGT elements that GTGACTTCCGAGGCTAGGTCATAAAAGTGCCATGCAGCTTCCGCCT belong to TGCTCTCTTGGGACGCTCGCTCTTGGAACCCAGCCGCCATGCTG TGAGGAAGCCCAAGCAGCCCATGGAGAGGCCCACGTGGAGAGGA MLT1G1 ACTGAGGCTTCCGGCCGACAGCCCCAGCTGAGNTCCCAGCCGACA subfamily GCCAGCATCAACTTGCCAGNCATGTGAGTGAGCCATCTTGNAGGTGATTCCAGCCCCCAGCCTTTGAGCCGCCCCAGCTGACGCCGCGTGAttorney Docket No. 60448-717.601SEQ SequencesIDNoGAGCAGAGACGAGCCGTCCCCGCCGAGCCCTGCCCAAATTGCAGA TTCGTGAGCAAAATAAATGATTGTTGTTGTTTTAAGCCACTAAGTT TTGGGGTGGTTTGTTACGCAGCAATAGATAACCGGAACA81 TGTGGCAGATTGTATTTTCCAAAGATGGCCGCAACAATATCTCCCA Consensus TCCCACATGCTCTTCTTACAATGTGACCTTGACACTCCTCCCAT sequence for CGAGAGGTGGGGTCTATGTCCCCTCCCCTTGAATCTGGGCGGGCCT transposable TTGTGACTGCCTCGACCAATAGAATACGGCGGAAGTGACGCTGT elements that GTGACTTCCGAGGCTAGGTCATAAAAAGGCCATGCAGCTTCCGCC belong to TTGCTCTCTTGGGACGCTCGCTCTTGGAACCCAGCCGCCATGCTG TGAGGAAGCCCAAGCCACATGGAGAGGCCACGTGTAGGTGTTCCG MLT1G3 GCCGACAGCCCCAGCTGAGGTCCCAGCCGACAGCCAGCATCAACC subfamily GCCAGACATGTGAGTGAAGAAGCCTCCAGATGATTCCAGCCCCCA GCCGTCGAGTCACCCCCAGCCTTCGAGTCTTCCCAGCTGAGGCCC CAGACATCGTGGAGCAGAGACAAGCCATCCCCGCTGTGCCCTGTC CGAATTCCTGACCCACAGAATCCGTGAGCATAATAAAATGGTTGT TTTANGCCACTAAGTTTTGGGGTGGTTTGTTACGCAGCAATAGATA ACTGGAACA82 TGTGGTAGATTGATTGCAAAAATGGCCNCAATTCTTCACCCCTCCC Consensus TGTATCCACGCCCTTTGCAATGTGACTTTGCAGCTCCTCCCATC sequence for AAGAGGTGGAGTCTATTTCCCCACCCCTTGAATCTGGGCTGGCCTT transposable GTGACTTGCTTTGGCCAATAGAATGCGGCGGAAGTGACGNTGTG elements that CCAGTTCCGAGCCTAGGCCTCAAGAGGCCTTGCACGCTTCCGCTCT belong to CTCTCTTGGAACCCTGCCACCGCCATGTGAACAAGCCCGGGCTA GCCTGCTGGAGGATGAGAGACCACGTGGAGCAGAGCCGAGCCGTC MLT1H CCAGCTGAGGCCATCCTAGACCAGCCAGCCCCCAGCCAAGATCAG subfamily CAGAGCCGCCTACCCGACCCGCAGCTGACCGCAGACGCATGAGTG AGCCCAGCCGAGACCAGAAGAACCGCCCAGCTGAGCCCAGCCCA AATTGCCGACCCACAGAATCGTGAGCTAAAATAAATGGTTGTTGTT TTAAGCCACTAAGTTTTGGGGTGGTTTGTTACGCAGCAATAGCTA ACTGATACA83 GAAATTGGTACCTAGAAGTGGGGTGCTGCCGTAACAAAAACCTAA Consensus AACATGTGGCATTGGCTTTGGGACCGGGCGGCGGGCAGAGGCTGG sequence for AAAAGCGNCGAGGAGACTGTTAGTGGAGGCTGGAAGAGCAGTGA transposable GGAAACTGCTATTGGAGGCTGGAAAAANGGCGACCCGTGTTATGT elements that AGTGGCGGAACANTTGGCAAAACTGTCGCCTGCGGTAACNTGGAA belong to GATAGAAAATGTACCTAATGAACTTGTGGATCTGGCTAAGGAGAT TTCCAGGCAGAATGTTGAAAGTGCCAACTGGCTTCTTTTAGCTGCG MLT1H-int TATGATAAGGTACGGNAAGAGAGAGATGAGCTAAAGAAGGAACT subfamily GTTCAGTTTNCAAGCAGAATTTAGAGGAAATATAGAGGANCCAGG ACTTGCTGGGTTGGAAAATAAAACTGTTTCTCATCTCCAGTCTCTC CAGCCGGCAAAAGATTCTCAAAGTAAGAAATGGCCTCAGGGCAAA GATCAAATCAAGGGTGTGGCTGTAAGACCCTTTGTTAAGACCTCA GAAAGATTTAAGGCGGTGCCTNGTAGACCCTCTCAGCTAGACAAA AGGGCTTCTAAGAATCTTAAGGGCGTTGTCCCACAGCAGCCTGAC ACGCAGCCCAAAGTAGAGAGAGGCCTGTCTCGAAAAGAATTGTGG GTGTGGCTTTTGTCNAATGGAGTGGACTNNAATNNGATNCATAGG AAACCCACAAAGTTTTTAAGAGAATTGTATTGGCAAAAGCACCGC CAGCTTGGACTAAAAGGGACAGAGACAGTTCAAAATGAAAAGAGGCCTCTGGGCCCCCAACTTTCTACGGGCAGGAAGCAGGCTGAGAAAttorney Docket No. 60448-717.601SEQ SequencesIDNoAGCTACTCAGCTGCAAACACGGGCCATTTCTTATGGAAAAGGAAG GACGNCTCAGAGGGCAGAGCCAAGAGCCCAGAGGGCGGAGCCAA GAGCCANGGAGAACAATGGACTAGGGAACCACTCCCAGGGAGCA GAACCGGGCCCTAATCAAGGAACATTCCCTGCCCCCGGAGTAGGG GAACCTGGCAACATGTGCCCGGCTGGATTTCAGAATTGCTATGGA CCAGTGACTGCTATGTGCCTCCCATTCTTCCCCTTTTTGAATGGGA GTGTCTATTGCGGTTATCCTGTCCCTGTCTCACCATTGTATGTTGGG TGTGTGGGGGGCAGATAACTTGTCTTTTTAGTTCACAGGTCTCCGG ATCAAGAGGAGCCACACCCTGAGGAGCTGCACCCGAGGAGCCTC ATCCGCATCCGGACCTGATNTAGATNACGAGATCCTGGACTTCGA GCCTGATGCCGTAATTGGATGAGACTTTTGGGGGTCTTGGGANGG GGGTGAGCGTATTTTGCATGTGGGAGGAATGTGAATAATTTGTGG CCAGAGGGCAGACT84 TGTGGTAGATTAAAGATGGCCGCAAATTCTTTGACACTCCTCCCAT Consensus CGAGAGGTGGGGTCTATNTCCCCTCCCCTTGAATCTGGGCTGGC sequence for CTTAGTGACTGCTTTGACCAATAGAATGCGGCGGAAGTGACGCTG transposable TGCGACTTCCGAGGCTAGGTCNTAAGAAGCCTTGCAGCTTCCGCC elements that TNGGTCTCTTGGAACGCTCGCTCTGGGAGCCCTGAGCCGCCATGTA belong to AGAAGTCCGACTACCCTGAGACCGCCATGCTGGAGAGGCCACGT GNAGGCGCTCTGGTCGACAGTCCCAGCTGAGCCCAGCCTTCCAGC MLT1H1 CATCCCCGCCAAGGCGCCAGACATGTGAGTGAAGCCGTCTTGGAC subfamily CCTCCAGACCAGCCCANCCGCCAGCTGAATACCACCGAGTGACCT CAGTCGACGCCACGTGGAGCAGAAGAACCGCCCAGCTGAGCCCTG CCCGAATTCCTGACCCACAAAATCGTGAGANATAATAAAATGGTT GTTGTTTTAAGCCACTAAGTTTTGGGGTAGTTTGTTACGCAGCAA TAGATAACCGGAACA85 TGTGGTAGACTGTTACATTGGTGGCCCCCAATGAACCACGCCTCCC Consensus GGTATTCACGCCCTTGTGTAGTCCCCTCCCACATTGACTCTGGG sequence for CTTGGCCATGTGACTTGCTTTGGCCAATGGGACATTAGCAAACGTG transposable ATGCAAGCAGAGGCTTGANAAGCGCTTGCGCATTGGGGCTTGTC elements that CTCTTGGAACGCTCCCTCTTGGAANCCAGCTGCCATGCTGTGAAGA belong to AGCCCAGGCTAGNCTGCTGGANGATGAGAGGCCACGTGGAGAGA GGCCCTGGAGGATGAGAGGCCATCTTGGACGTTCCAGCCCCAGCC MLT1H2 GAGCTCCCAGCTGAATGCAGCCACATGAGTGACCCCAGCTANACC subfamily ACGTGGAGCAGAAGAACCGCCCAGCTGAGCCCAGCCAACCCACA GAATCGTGAGAAATAATAAATCGTTGTTGTTTTAAGCCACTAAGTT TTGGGGTGGTTTGTTACGCAGCAATAGATAACTGAAACA86 TGTGGTAGTCATTAGTGCTGTTCACCAAATATTTCCGGCTCTCTNC Consensus CTTCCGGGCACATGGTAGGATTGCACTTCCCCGCCCCCTTGAAG sequence for TTAGGCGTGGCCATGTGACTTGCTTTGGCCAATGAAATGTGAGCGG transposable AAGTGACGTGTGTCACTTCCGGGCGGAAGCTTTAAGAGCCAGTG elements that CGTGATTCGCCACGTTCCCCTTTCCCTCTGCCACGGCGACCGGCAA belong to TGTTCCAGATGGTGGCTGCTCCGTCAGCCTGGGTCCCGGAGTGA GGACGACGTGGAGCAGAGCCCCCAGCCGACCCGCGATGGACATGT MLT1I AGCATGAGCGAGAAATAAACCTTTGTTGTTTTAAGCCACTGAGAT subfamily TTGGGGGTTGTTTGTTACCGCAGCATAACCTAGCCTATCCTGACTG ATACA87 TGTGGCAGAGACTGCTAGTTGTCCCCCAATATCCATTCTCCCCTTC Consensus TTCCTTAGTAATAGAACCCCCGATTTTTAGCTGGGCACATGGCC sequence for GCCCAGAATAAAGACTACATTTCCCAGCCTCCCTTGCAGCTAGGTG transposable TGGCCATGTGACTAAGTTCTGGCCAATGGGATGTAAGCGGAAGT elements that GNCGTGTGCAACTTCCGGGAAGTGTCCTTAAAGGGAGGGGGCGTG belong to CCCTTCTTTTCCCCTTCCTCCTTCCTGCTGNCTGGAATGCGGACGTGATGGCTGGAGCTCNAGCAGCCATCTTGGACCATGAGGTGGAAGAttorney Docket No. 60448-717.601SEQ SequencesIDNoCCACGTGCTGAGGATGGCGGAGCAACAAGATAGAAGGAGCCTGG MLT1J GTCCCTGATGACCGTGGAGCCGCCATACCAGCCCTGGACTGCCTAC subfamily CTCCGGACTTCTTTTACGTGAGAGAGAAATAAACTTCTATCTTGT TTAAGCCACTGTTATTTTGGGTTTTCTGTTACTCGCAGCCGAACCTA ATCCTAACTGATACA88 GAAATTGGTACCTAGAAGTGGGGTGCTGCCATAACAAAAACCTAA Consensus AATATGTGGCATTGGCTTAGCGGTCGGGCGGCGGGCGGCGAGGAA sequence for ACNGATATCGNAGGCTGGAAAGNTGGNGACCCNTGTTATGCAGTG transposable GCAAAACATTTGGTAAAACTGTCGCCTGCGATAACTTGGAAGGCA elements that GACCACGTGCCTACTGAGCCTGTAGCTCTAGGGGAAGNGGTTGGA belong to AAAANTCAGAATGTTAGTGTGTGTTGGCTGCTNCTNGCTGCNTTT AGCAAGGTATTACAAGAAAGAGATGAGCTCAGGAAAGAATTGGC MLT1J-int CGGTTTGCAAGCAGAAATGAAAGGGAATAGAGAGAGTCCAGAAA subfamily TTTGGGGCCTTGCAGGGTTGGAAAAGCCAACTGCTTCTGNACCCCA AACAGTAAGAGATAAGACTGAAAAAGGCTTTGAGCAACAAAGGC CCATTAAGACTTCTCGCCAGACAAAGGGACTCAGCCCTGCGGCAA AGATCAGATTAAGGGTGTTGCCTTCCCACCCAAGCCTATTGTTTCA GATGGCCTCAAGGTAGCCGCCATTAAGTTGAGAGAGAGGGGATGG GCAGAGCACAGAGGCCAGNAAATAAAAGANTAAAGCAGGCTTGA GAACTATGTCTAGGAAAGAACTTTGGNTGTGGTTACTGGCACATG GAACTGACTGGAAGCAAATAGATCAGAAGCCTACTAAGTTTTTGA GGGAATTGTATTGCCAAAGAAACCACAAGCCTGGCCTGNAAAAGC CTGTGACTGTTCGANCCCTAAAACAACCCTTGGGCCCCCAAACTTG CACCAGCAGGAAGCGGGCTGCGAAAGCTGTGCAGCCCCCAAGGA GGGCATACTCCCCAACGCCCACTTCAGATGTGGCCANGGAGGATA ATGGACAAGGAAGAACCTCCCAGAGGGCGGAGCCAGGGGCCACG GAGAACAATGGACAAGGGAGTTCCTCCCAGAGAGCAGAATCAGG GTCTAATCAAGGAACTTCCCCCACTGCCAGGGCAGGGGGTCTTCA CAATNCCTGCCCAGCAGGATTTCANAATTGCTATGGACCAGTGACT GCTGTGTGTCTCCCATTCTTCCCTTTTCCGAATGGGAGTTTTTATTG CGGTTATCCTGTCCCTGCTCCACCATTGTATATTGGGTGTGTGGGG GGCAGATAACTTGTCTTTTAGTTCATAGGTCGCCGGACCACGAGGA GCCACATCCGGACCTGATGGAGAGGACTGCGCATCACCCAGAGA TCCTGGACTTTGAGCTGGATGCAGTAACTGGATGGGACTTTGGGTT GTCTCCCTTGGGGAGGGGGTGAGTGTGTTCTATGTGTGGGAAGA AGGGTGNAACGGATATTTGGTGGCCAGAGGGGCAGAC89 TGTGGCAGAGACTGGCTAGCTGTTCACCAAACCCGTTTCCTCTTCT Consensus TCCTGGGCACACAGCTAGACTACATTTCCCAGCCTCCCTTGCAG sequence for TTAGGTGTGGCCATGTGACTGAGTTCTGGCCAATGGAATGTGAGC transposable AGAAGTGATGTGTGCCACTTCCAGGCCTGGCCCATAAAAACCTCC elements that CATGCATNCTCCTCTCTATTCTCTCTTCCCTCTCTGCTGGCTGGATG belong to TCGACGCCCAGGGCGACCTTGGAAGCCACGTGTTGAAGATGGC AGAGCCTCCGTCAGCCTGGGTCCCTGAATGACTGCGTGGAGCAGA MLT1J1 GCCCCCCCCNACCCCCCCAGCACATCCAATTGGACTTTACGTGAG subfamily CGAGAAATAAACTTCTATTGTGTTAAGCCACTGAGATTTTGGGGTT TATCTGTTACAGCAGCTAGCGTTACCTTAACTAATACA90 TGTGGCAGAGACTGGCTAGNTGTTCACCAAANCCCGTTTCCTTTTC Consensus CTCCTGGGCACACAGCTAGACTACATTTCCCAGCCTCCCTTGCA sequence for GTTAGGTGNGGCCATGTGACTGAGTTCTGGCCAATGGAATGTGGG transposable CGGAAGTGATGTGCGCCACTTCCAGGCCTGGCCCATAAAAACCTC elements that CCACGCGATCCTCCACGCTCTCTCTCTTTCCCCATCTGCCGGCTGG belong to ATGCAGAGGATCCAGTGGAGGACTCCGAGGCCCTAGGGGATGGC GGAGCCACAAGATGGAAGGAGCCTGGGTCCCTGAATGACCGCGTG MLT1J2 subfamilyGAGCAGAGCCGCCCACCCCCCAGAACCACCCGCATTGGACTGTGAAttorney Docket No. 60448-717.601SEQ SequencesIDNoCGTGAGCGAGAAATAAACTTTTATTGTGTTAAGCCACTGAGATTTG GGGGTTGTTTGTTACAGCAGTTAGCCTACCCTGACTAATACA91 TGTAGTGGACATCTGTTGTTTTTGCCTGCCCAGCATCCATTCCCCCT Consensus TCTTCTGGTAACAGCACCCCGATTTTCCTTTGGGGAACCACCC sequence for CTCCCCCACTCTCAGTCCATGTGGTTCGGGTGGGGCTGACCCCACC transposable CCTCGGCTCCAGGGGTGGGCACGTGACCCAGGCCTGGCCAATCA elements that GAGCATTCCATCCCCCTGGCCACAGTGATTGGTTCAGGGATGGGC belong to ACGTGACCCAAGCCGGGCCAATGAGAGTCAGCCCTGGGACTTTTG CTGGAACTATTGGGAAAGAGANGCTCTCTTTCCGCTGGGGTTGCTA MLT1K AGCTGGNAGGATGTAAGCCTGGAGCTGCTGGCGGCCATCTTGCC subfamily ACCACGTGGGGAGAGCCTGCCTGAGAATGAAGCCAACACAGAGG AAAGCAGAGCCGAGAGATGGAGAGAGACAGANTCCTGATGACAT CGTTTGAGCNCCTGGATCCAGCCGTGCCTGAAGCCAGANCTACCC CTGGACTTTTCAGTTACGTGAGCCAATAAATTCCCTTTTTTGCTTAA GCCAGTTTGAGTTGGGTTTCTGTCACTTGCAACCGAAAGAGTCCTG ACTAATACA92 TGTGGCAGACACTGTTGGTTGCCTACCCAACAGCCATTCTCCCCTT Consensus CTTCCTTGCTAACAGAACCCCGATTTTGTTCAGGTATCNGGCGG sequence for CCATGTGCTTCAGGGGAGGCTGGNCCCCTCCCCAGCCCCAGGGGG transposable TGAATCNTGATTGGTCTAAGCCAATCATGGTAATCCCATTCCCCT elements that TGCCAGTGATTGGTTTAGGAATGGGCATGTGACNCAATTCTGGCCA belong to ATGAGACGTGAGGGGAAGTCTGCTGGGGGGCTTCTGGGAAAGNT TTCCTCGCTCTTAAAAAAAGGACATAAGGAAGAGATGTCCTCTTTT MLT1L CTTGCCTCTGGACGTTGTCGTGTGNGGATGTGATGCCTGGAGCT subfamily GCNGCAGCCATCTTGCGACCATGAGGGGACAAGCCTGAGAGGAAA AGCCAACACGCTGAGGATGGCAGAGCGGAAAGATGGAAAGAACC TGGGTCCTTGATGACATCGTTGAGCCGCTGAATTAACCAACCCTGG AACCGCCCTACCTCCGGACTTCTTGTTATGTGAGATAATAAATTT TCCTTATTGTTTAAGCCANTTTGAGTTGGGTTTTCTGTTACTTGCAG CCGAAAGCATCCTAACTGATACA93 TGTACTAGACATGTCAATCACGGTGCCTGCCACGCCCACAGCCCCT Consensus TCTAAGGGAAACTGCCCCGCCCACAGCCCCTGCTGAAGGGGCAG sequence for CCCTAGGCGGCCATGTTTTGTACCACGTGACCCTGCCCTCCCCTGG transposable CCACAGCTGATTGGACCAGGGGTGGGCACCTGACCCAAGGGCAG elements that CCAATCCATAGGCTGGCCAGCGACCTATGACGTGGCCTGGCGCGA belong to AAAGATGAGCTGGGCCAATCAGATTCTCTCTCTCGGGAATTTGAA CTGGGAAACACGGAGAGAATGAGGCAGTTAGCAGCGGGAGCTGA MLT1M AGCTGAAAGGATGCATAGAGAGAAGCCATGAGGTAGAGTCGGGG subfamily CCATGATGGGCCATGTGCAAGCCGAAGTTATGAGGAAGCAGAAAC TATGAGTAAGCAGAGGAAGCCGGTCGGTAGAGAGAAGAGAACGG AGCAGACGCGCAGAGAGAAGCNGAGACGCGTGATGAGAGAGGGA CCGGACGAGAGCNGCNGAGGTCCCTAGAGCTGCCCCGGTTCCGGC CGCTTCCAGTCCCTGTTCCTGGCGNTTTCCCAGTTCCAGTTCCGGTC CACGTGTATCCTTACAATAAACCCCCCTTTTCTTGAGNTAACTTGA GTGAGTCTCTGTTCCTTGCAACCAAAAGAGCCTAACTAAAACA94 TGTAGTGGACATTTGTCATTCTTTTTGGCCGCCCAGCATCTGAACN Consensus CCCTTCCTATGTTTGGGGAATTCCCCACCTTATGAGTCCCGCCT sequence for CCCCAAGGTAGAAGCCAGAAACTCGCTTTCCCAGCCTCCCTTGCAG transposable CTAGGGCGCGGGCACGTGACCTAGGCTCCGCCAATCAGACGCAC elements that CCGCNCCAGACTTTGAATCGGAAGCTAGTGACGCAAGGAAGCAGG belong to GACCGCGCGGAATCCATTCTCTGGCGAGGGTGGCGGCAGCTGGCA TCCAGTTTCCAGAGGCAGCAGTGGCAGNGGTTCTAGCGGCGGCGT MLT1N2 CCAGCGCTCATGTGTGGTGCAAGCTGCGGTGTCTGTGCCCAGCGG subfamilyCGGCAGCAGTGGTGTCCTCACCGGACCAGTTCTGCGGCGTGATTTTAttorney Docket No. 60448-717.601SEQ SequencesIDNoGGGCATTGTTCCTGGCTGCGTAGCCTCCAAGCCTGGTTCTCCGG CCCTCCCGGAGATTCTGTGAGCTACCCAATATCCTTTCAATAAATT CCTTTTCTGCTTAAATTAGCCAGAGTCGGTTTCTGTTGCTTGCA ACTAAGAACCCTGACTGATACA95 TGTAGTGGACACCTTTTGGGGTGTCTGCCCAGCCCCCCTTCTCTGG Consensus GAACCGCCCCCCCACCCACAGGGGTGGGCCCCCGGCAGCCATGT sequence for TTGTACTACGTGACCCCGCCCCCCTGGCCACAGCTGATTGGACCAG transposable GGGTGGACACCTGACCCAAGCTGGGCCAATCAGATTCTCTCTCC elements that CGGGAATTTGGAATTGGGACTNAGAGATNCTAGTCAGTCTCTGCT belong to GGTCGCTTGAACTGGGGANATGTAAACTCGGGAGCTGTGGGGCGG CCATNTTCCGCCATGTGNACGGAGAAGCAGAGAAAGCCGGTCTGC MLT10 AGAGAGAGGAGAATGAAGCAGACGCGCAGAGAGAAGCAGAGACG subfamily AGAGACCGGGTGGCCTCAGAGACAGAGAAAGATGGAGCCGATTCT CTCCTGAGGCCCGGCTGCATTCCTGCCCTTGGGTTCCGTGAGACAC CCCTGTATCCTTATAATAAATTCCCCTTTTTTGCTTAAGCTAGCTCG AGTGGGTTTCTGTTACTTGCAACCAAAAGAGCCTTGACTAAGA CA96 TGTGATGGTTAATACTGAGTGTCAACTTGATTGGATTGAAGGATAC Consensus AAAGTATTGATCCTGGGTGTGTCTGTGAGGGTGTTGCCAAAGGA sequence for GATTAACATTTGAGTCAGTGGGCTGGGAAAGGCAGACCCACCCTT transposable AATCTGGGTGGGCACNATCTAATCAGCTGCCAGCGCGGCTAGAAT elements that ATAAGCAGGCAGAAAAACGTGAAAAGAGAGACTGGCCTAGCCTC belong to CCAGCCTACATCTTTCTCCCGTGCTGGATGCTTCCTGCCCTCGAAC ATCGGACTCCAAGTTCTTCAGTTTTGGGACTCGGACTGGCTCTCCT MLT2A1 TGCTCCTCAGCTTGCAGACGGCCTATTGTGGGACCTTGTGATCG subfamily TGTGAGTTAATACTTAATAAACTCCCCTTTATATATATATNTATTCC ATTAGTTCTGTCCCTCTAGAGAACCCTGACTAATACA97 TGTGATGGTTAATACTGAGTGTCAACTTGATTGGATTGAAGGATGC Consensus AAAGTATTGTTCCTGGGTGTGTCTGTGAGGGTGTTGCCAAAGGA sequence for GATTAACATTTGAGTCAGTGGACTGGGAGAGGCAGACCCACCCTC transposable AATCTGGGTGGGCACCATCTAATCAGCTGCCAGCGCGGCCAGAAT elements that ANAAAGCAGGCAGAAGAACGTGGAAAGACTAGACTGGCTNAGTC belong to TTCCGGCCTNCATCTTTCTCCCGTGCTGGATGCTTCCTGCCCTCGA ACATCGGACTCCAAGTTCTTCAGCTTTGGGACTCGGACTGGCTTCC MLT2A2 TTGCTCCTCAGCTTGCAGACGGCCTATTGTGGGACCTCACCTTG subfamily TGATCGTGTGAGTCAATACTCCTTAATAAACTCCCCTTTATATATA CATCTATCCTATTAGTTCTGTCCCTCTAGAGAACCCTGACTAAT ACA98 TGTGATGGTTAATTTTATGTGTCAACTTGACTGGGCCANGGGATGC Consensus CCAGATAGCTGGTNAAACATTATTTCTGGGTGTGTCTGTGAGGG sequence for TGTTTCCGGAAGAGATTAGCATTTGAATCGGTAGACTGAGTAAAG transposable NAGATCGCCCTCCCCAATGTGGGTGGGCATCATCCAATCCGTTGA elements that GGGCCTGAATAGAACAAAAAGGCGGAGGAAGGGNGAATTCGCTC belong to TCTCTGCTTGAGCTGGGACATCCGTCTTCTCCTGCCCTCGGACATC GGCGCTCCTGGTTCTCGGGCCTTCGGACTCGGACTGGGACTTACAC MLT2B1 CATCGGCTCCCCTGGTTCTCAGGCCTTCGGACTCGGACTGGAAC subfamily TACACCACCGGCTTTCCTGGGTCTCCAGCTTGCAGACGGCAGATCG TGGGACTTCTCAGCCTCCATAATCGCGTGAGCCAATTCCTCATA ATAAATCTCTTTCTATATATCTATATATATCCTATTGGTTCTGTTTC TCTGGAGAACCCTGACTAATACA99 TGTGATGGTTAATTTTATGTGTCAACTTGACTGGGCTAAGGGATGC Consensus CCAGATAGCTGGTAAAACATTATTTCTGGGTGTGTCTGTGAGGG sequence for TGTTTCCGGAAGAGATTAGCATTTGAATCAGTAGACTGAGTAAAG transposableAAGATCCGCCCTCACCAATGTGGGCGGGCATCATCCAATCCGTTGAttorney Docket No. 60448-717.601SEQ SequencesIDNoAGGGCCCGAATAGAACAAAAAGGCGGAGGAAGGGCGAATTCNCT elements that CTCTCTTCTTGAGCTGGGACATCCATCTTCTCCTGCCCTCGGACAT belong to CGGAGCTCCTGGTTCTCGGGCCTTCGGACTCCGGGACTTACACCAG MLT2B2 CGGCCCCCCTGGTTCTCAGGCCTTCGGACTCGGACTGAATTACA subfamily CCACCGGCTTTCCTGGTTCTCCAGCTTGCAGACGGCANATCGTGGG ACTTCTCGGCCTCCATAATCGCGTGAGCCAATTCCCATAATAAA TCTCCTCTTATATATCTCTATATATCCTATTGGTTCTGTTTCTCTGG AGAACCCTGACTAATACA100 TGTGATGGTTAATATTAGGTGTCAACTTGATTGGATTGAAGGATGC Consensus CNAGATAGCTGGTAAAGTATTGTTTCTGGGTGTGTCTGTGAGGG sequence for TGTTGCCAGAGGAGATTAACATTTGAGTCAGTGGACTGGGAGAGG transposable AAGACCCACCCTCANCGATGTGGGTGGGCACCATCCAATCGGCTG elements that CCGGCNCGGCTAGAACAAAAAGGCAGAGGAAGGGCGAATTTGCT belong to CTCTCTCCTGGAGCTGGGACACCCTTCTCCTCCTGCCCTCGGACAT CAGANCTCCAGGTTCTTCGGCCTTTGGACTCTNGGACTTACACCAG MLT2B3 CGGTTTNCCGGGCTCTCGGGCCTTCGGCCACAGACTGAAGGCTG subfamily CACCGTCGGCTTCCCTGCTTTTGAGGCTTTNGGACTCGGACTGAGC CACGCTACCGGCTTCCCTGGCTCCCCAGCTTGCAGACGGCCTAT CGTGGGACTTCNCGGCCTTCGTGATCGTGTGAGCCAATTCCCCTAA TAAATCCCCTTTATCTATCCTATTAGTTCTGTCCCTCTGGAGAA CCCTGACTAATACA101 TGTGATGGTTAATTTTATGTGTCAACTTGACTGGGCCACGGGGTGC Consensus CCAGATATTTGGTCAAACATTATTCTGGGTGTGTCTGTGAGGGT sequence for GTTTCTGGNATGAGATTAACATTTGAATCGGTAGACTGAGTAAAG transposable CAGATTGCCCTCCCTAATGTGGGTGGGCCTCATCCAATCAGTTGA elements that AGGCCTGAATAGAACAAAAAGGCTGACCCTCCCCCGAGTAAGAGG belong to GAATTCCTCCTGCCTGACTGCCTTCGAGCTGGGACATCGGTCTTT TTCCTGCCTTCGGACTCGAACTGAAACATCGGCTCTTCCTGGGTCT MLT2B4 CGAGCCTGCCGGCCTTCGGACTGGAACTACACCATCGGCTCTCC subfamily TGGTTCTCAGGCCTTCGGACTCGGACTGGAACTACACCATCGGCTC TCCTGGGTCTCCAGCTTGCCGACTCGNNNTGCAGATCTTGGGAC TTNTCAGCCTCCATAATCGCGTGAGCCAATTCCTTATAATAAATCT CTCTCTTNTATATATATACCACATCCTATTGGTTCTGTTTCTCT GGAGAACCCTAATACA102 TGTGATGGTTGATTTTGGGTGTCAACTTGACTGGATTAAGGGATAC Consensus CCAGATAGCTGGTAAAGCATTATTTATTCTCAATCANCGCATNA sequence for ATTATTCTCAATGCTTCAGTAGGCACTGAGCCCGTCCCTCTTCTGCT transposable GAAAGGGAAACCCAGGTGGTTTGGCATTTGATTAGAATGATTG elements that GGCTGCCCCAGGTGTGTCTGTGAGGGTGTTTCCGGAGGAGATTGG belong to CATGTGAGTCGGTGGACTGAGTGGGGAAGATCCGCCCTCAATGTG GGCGGGCACCATCCAATCGGCTGGGGGCCCGGATGGAACAAAAA MLT2B5 GGCAGAGGAAGGGCGAATTCTTGCNCTCTCTCTTCCGGAGCCGGG subfamily ACGCCCTTCTTCTCCTGCCCTTGGACGTCAGAACTCCAGGTTCTCC GGCCTTTGGACTCCGGGACTTGCACCAGCGGCCCCCGGGCTCTCA GGCCTTCGGCCTCGGACTGAGNNACTGNGAGTTACACCATCGGCT TCCCTGGTTCTNAGGCCTTCGGACTTGGACTGAGCCACGCCACCG GCTTCCCTGGNTCTCCAGCTTGCAGATGCAGNCGGCCTATCGTGGG ACTTCTCAGCCTCCGTAATCGCGTGAGCCAATTCCCCTAATAAA TCCCTTCTCATATATCTNTCTATATATATATATATNTNTNTATATAT CCTATTGGTTCTGTCTCTCTGGAGAACCCTGACTAATACA103 TGTGATGGTTAGTTTTATGTGTCAACTTGGCTAGGCTATAGTACCC Consensus AGTTATTTAATCAAACACTAATCTAGGTGTTGCTGTGAAGGTAT sequence for TTTGTAGATGTGGTTAACATCTACAATCAGTTGACTTTAAGTAAAG transposableGAGATTACCCTCGATAATGTGGGTGGGCCTCATCCAATCAGTTGAttorney Docket No. 60448-717.601SEQ SequencesIDNoAAGGCCTTAAGAGCAAAAACTGAGGTTTCCCGGAGAAGAAGAAAT elements that TCTGCCTCAAGACTGCAGCATCAACTCCTGCCTGAGTTTCCAGCC belong to TGCCGGCCTGCCCTACGGATTTCGGACTTGCCAGCCCCCACAATCG MLT2C1 CGTGAGCCAATTCCTTAAAATAAATCTCTTTCTACACACATCCT subfamily ATTGGTTCTGTTTCTCTGGAGAACCCTGACTGATACA104 TGTGATGGTTAATTTTATGTGTCAACTTGGCTAGGCTATGGTGCCC Consensus AGTTGTTTGGTCAAACACTAGTCTAGATGTTGCTGTGAAGGTAT sequence for TTTTTAGATGTGATTAACATTTACAATCAGTNGACTTTGAGTAAAG transposable CAGATTACCCTCCATAATGTGGGTGGGCCTCATCCAATCAGTTG elements that AAGGCCTTAAGAGCAAAGACTGAGGTTTCCCGAAGAAGAAGGAAT belong to TCTGCCTCAAGACTGCAACATAGAAATCCTGCCTGAGTTTCCAGC CTGCTGGCCTGCCCTGCGGATTTCGGACTCAAGACTGCAACATCAA MLT2C2 CTCTTACCTGAATTTCCAGCCTGCCGGCCTGCCCTACAGATTTC subfamily GGACTTGCCAGCCCCCACAATCGCGTGAGCCAATTCCTTAAAATA AATCTCTCTCTACACATATCCTATTGGTTCTGTTTCTCTGGAGAA CCCTGACTAATACA105 TGTGATGGTTAATTTTATGTGTCAACTTGGCTAGGCCACGGTGCCC Consensus AGATATTTGGTCAAACATTANTCTGGATGTTTCTGTGAAGGTAT sequence for TTTTTAGATGAGATTAACATTTAAATCAGTAGACTTTGAGTAAAGC transposable AGATTACCCTCCATAATGTGGGTGGGCCTCATCCAATCAGTTGA elements that AGGCCTTAAGAGAAAAAGACTGANNTCCCCCGAGGAAGAGGGAA belong to TTCTGCCNNCAGACTGCCTTCGGACTCGAGCTGCAACATCAACTCT TCCCTGGGTCTCCAGCCTGCCGGCCTACCCTGCAGATTTTGGACTT MLT2D GCCAGCCTCCACAATCGCGTGAGCCAATTCCTTAAAATAAATCT subfamily CTCTCTACACACATCCTATTGGTTCTGTTTCTCTGGAGAACCCTGAC TAATACA106 TGTGCTGGATTGTNCTGTTGTCAACTTGGTTAAGCTGGGAACTACG Consensus TTTCCCAGAATCCCCTTCCCTGTATGGTTCTGGGTTAGAGTTGG sequence for CCAAAGAGGAACTTGCGCGAGATTTGGGAGGCGGAAGTGAAGCA transposable GCAGCCATTACTCTCTGAAGGTCGTCGCGGTCAGACGCGGTGAGA elements that GACAGACGCAGAGGTGCCCAGCGGGTTCCAGCTTGTCCTCGCTCTC belong to CCCCGCTCCGCGTCCAGCTCTTCTTCCCGACTGCCGGCCCTGCTG ACCAACAGCGGCCCCAGGCCCACCACCAGACGCTTGGCTGCGGAC MLT2E CCACAGAGGCGGTAGCCACGCAGAGGCAACAGCTTTCCATAGACC subfamily TCTCCACNAGCTCCCCTTCATGGTCCCACTTCAGCGGCTGGACGTG CCTGGCTTCTCAGATTTCCCCGCAAGCTCCGACTCGTCCACCCG CGCCAGTGCTTCAGGAGGGGCTGGTTAGTGACTTTCTCTGATCCTC CAACTCCCCCTTCCAGACCTTCACTTCCCCAGCTCCTCCCACAA TTGTGTAAGGTCTAATTCCTATAATAAATCCCTTATCCCATAACAC TCATAGTGGCTCTGCTTCCCTGACTGAACCCTGACTGATACA107 TGTGGTGGCTTTGTAATGTGTCAACTTGGCTAGGCTGAACTACGTT Consensus TCCCAGAATTCCCTTCCCTGTATGTTTCCGGTTAGGGTGGGCCA sequence for CAAGAGANATTCTGCGCGAGATTTGGAGGGCGGAAGTGAAGCAGC transposable AGCCATNTTGTTTTTNATGCTCGGAAGGTCGGNGCAGGGNCCGCA elements that GGCGCTNTTGCAGCTCACGCACGTTGTCGCTNATCTGCTGGCTCAC belong to CTCGTTGGCGTGGGGCAGCAGCCGGGCCTGCAGCTGCTCCACCT TCCCCTGGATCCTCCTTCAGCTTCTCCGACTCCTGGGCCAGGTGTG MLT2F TGTTTAGCTCCGTGACGAAGGGCGCCAGCTTCTCCTGCAGGACA subfamily CCCGCATCATCAAGGTCGGAGGCAGCGAGAGACTGACACGGGTTC CAGTCCGTCCTCGTGGGTTCCAGCTCGTGCTCGTGGGTTCCAGCT TGTCCTTGCTCTCCCCCACTTCACATCCATCTTCCCTTCCCGACTGC CTGCCCTGCGGACTTCAAGCTCCAGCATCAGACGCAAAGACAACAGCCTTACAGAGACTGCTTAACCAGCTCCCACAATTGCGTAAGGTAttorney Docket No. 60448-717.601SEQ SequencesIDNoCAAATCCCTGTAACAAATCCCTTATTATATATATCTCCTAGTGG TTCTGCTTCTCTGATTGAACCCTGACTGATACA108 GAAAATTGGTACCGAGGAGTGGGGCATTGCTATAAAGATACCTGA Consensus AAATGTGGAAGCGGCTTTGGAACTGGGTAACGGGCAGAGGTTGGA sequence for AGAGTTTGGAGGGCTCAGAAGAAGACAGGAAGATGAGGGAAAGT transposable TTGGAACTTCTTAGAGACTGGTTAAATGGTTGTGACCAAAATGCTG elements that ATAGTGATATGGACAGTGAAGNCCAGGCTGACGAGGTCTCAGATG belong to GAAATGAGGAACTTATTGGGAACTGGAGCAAAGGTCACCCNTGTT ATGCCTTAGCAAAGAACTTGGCTGCATTGTGTCCATGCCCTAGGGA MST-int TCTGTGGAAGTTTGAACTTAAGAGTGATGACTTAGGGTATCTGG subfamily CGGAAGAAATTTCTAAGCAGCAAAGCGTTCAAGATGTGGCCTGGC TGCTTCTAACAGCCTACGNTCAGATGCGGGAGCAAAGAAATGACT TAAAGTTGGAACTTATATTTAAAAGGGAAGCAGAGCGTAAAAGTT TGGAAAATTTGCAGCCTGGCCATGTGGCAGAAAAGAAAAANCCAT TTTCAGGAGAGGAATTCAAGCAGGCTGCGGAGCAACCACTTGCTA GAGAGATTTGCATGACTAAAAGGGAGCCAAGTGCTAATANCCAAG ACAATGGGAAAAAGGCCTCGAAGGCATTTCAGAGATCTTCGAGGC AGCCCCTCCCATCACAGGCCCAGAGGCCTAGGAGGAAAGAATGGT TTCGTGGGCCAGGCCCAGGGCCCCGCTGCCCTGCGCAGCCTCGGG ACACTGCTCCCCGCATCCCGGCCGCTCCGGCTCCAGCCGCGGCTC AAAGGGCCCCAGGTACAGCTCGGGCCGCCGCTTCGGAGGGCGCAA GCCATAAGCCTTGGCGGCTTCCACGTGGTGTTAAGCCTGCAGGCG CACAGAATGCAAGAGTGAAGGAGGCTTGGCAGCCTCCGCCTAGAT TTCAGAGGATGTATGGGAAAGCCTGGGTGCCCAGGCAGAAGCCTG CTGCAGGGGCGGAGCCCTCACAGAGAACCTCTACTAGGGCAGTGC CGAGGGGAAATGTGGGGTTGGAGCCCCCACACAGAGTCCCCACCG GGGCACTGCCTAGTGGAGCTGTGGGAAGGGGGCCACCGCCCTCCA GACCCCAGAATGGTAGANCCACCGGCAGCTTGCACCCTGAGCCTG GAAAAGCCGCAGGCACTCAACTCCAACCCGTGAGAGCAGCCACGG GGGCTGNACCCTGCAAAGCCACAGGGGCGGAGCTGCCCAAGGCCT TGGGAGCCCACCCCTTGCACCAGTGTGCCCTGGATGCGGGACATG GAGTCAAAGGAGATTATTTTGGAGCTTTAAGATTTAATGACTGCC CTGCTGGGTTTCGGACTTGCGTGGGGCCTGTAGCCCCTTTCTTTTG GCCGATTTCTCCCTTTTGGAATGGGAATGTTTACCCAATGCCTG TACCNCCATTGTATCTTGGAAGTAAATAACTTGTTTTTGATTTTACA GGCTCATAGGTGGAAGGAACTTGCCTTGTCTCAGATGAGACTT TGGACTTTGGACTTTTGAGTTAATGCTGGAATGAGTTAAGACTTTG GGGGACTATTGGGAAGGCATGATTGTATTTTGCAATGTGAGAAG GACATGAGATTTGGGGGGGCCAGGGGCGGAA109 TGATATGGTTTGGATCTGTGTCCCCGCCCAAATCTCATGTCGAATT Consensus GTAATCCCCAGTGTTGGAGGNGGGGCCTGGTGGGAGGTGATTGG sequence for ATCATGGGGGCGGATTTCTCATGANCGGTTTAGCACCATCCCCTTG transposable GTGCTGTTCTCGTGATAGTGAGTGAGTTCTCACGAGATCTGGTT elements that GTTTAAAAGTGTGTGGCACCTCCCCCCTCGCTCTCTCTTNCTCCTGC belong to TCCGGCCATGTGACGTGCCTGCTTCCCCTTCGCCTTCCGCCAT GATTGTAAGTTTCCTGAGGCCTCCCCAGAAGCCGANNAGATGCCA MSTA NCGCCATGCTTCCTGTACAGCCTGCGGAACCGTGAGCCAATTAAA subfamily CCTCTTTTCTTTATAAATTACCCAGTCTCAGGTATTTCTTTATAGCA GTGCGAGAACGGACTAATACA110 TGCTATGGTTTGGATGTTTGTCCCCGCCAAAACTCATGTTGAAATT Consensus TGATCCCCAATGTGGCAGTGTTGGAGGTGGGGCCTAGTGGGAGG sequence for TGTTTGGGTCATGGGGGCGGATCCCTCATGAATAGATTAATGCCCT transposable CCCTCGNGGTGGGNGTGAGTGAGTTCTCGCTCTNNCGCGGGAAT elements thatGGATTAGTTCCCGCGAGAGCGGGTTGTTAAAAAGAGTCTGGCGNCAttorney Docket No. 60448-717.601SEQ SequencesIDNoTCCCTCCTCTCTCTCTCTTGCTTGCTTCCTCTCTCGCCATGTGAT belong to CTCTGCACACGCCCGCTCCCCTTCCNCTTCACTTTCCGCCATGAGT MSTA1 NGAAGCAGCCTGAGGCCCTCACCAGATGCAGCTGCCCGNACCNT subfamily GCTTTTTNNCCAGCCACCAGAATCGTGAGCCAAATAAACCTCTTTT CTTTATAAATTACCCAGCCTCAGGTATTCCGTTATAGCAACACA AAACGGACTAAGACA111 TGATATGGTTTGGATGTTTGTCCCCTCCAAATCTCATGTTGAAATG Consensus TGATCCCCAGTGTTGGAGGTGGGGCCTGGTGGGAGGTGTTTGGG sequence for TCATGGGGGCGGATCCCTCATGAATGGCTTGGCGCCGTCCCCNTGG transposable TGATGAGTGAGTTCTCGCTCTGTTAGTTCACGCGAGATCTGGTT elements that GTTTAAAAGAGTNTGGCACCTCCCCCCTCTCTCTCTTGCTCCCGCTC belong to TCGCCATGTGACGCGCCTGCTCCCCCTTCGCCTTCCGCCATGA TTGNAAGCTTCCTGAGGCCTCACCAGAAGCCGAGCAGATGCCGGC MSTB GCCATGCTTCCTGTACAGCCTGCAGAACCGTGAGCCAANTAAACC subfamily TCTTTTCTTTATAAATTACCCAGCCTCAGGTATTCCTTTATAGCAAC GCAAGAACGGACTAACACA112 TGCTATAGTTTGGATGTTTGTCCCCTCCAAACCTCATGTTGAAATTT Consensus GATCCCCAGTGTTGGAGGTGGGGCCTAATGGGAGGTGTTTGGG sequence for TCATGGGGGCGGATCCCTCATGAATGGNTTGGTGCCCTCCCTCGGG transposable GTGGGGATGAGTGAGTTCTCGCTCTATTAGTTCCCGCGAGAGCT elements that GGTTGTTAAAAAGAGCCTGGCACCTCCCTCCTCTCTCTCTTGCTTCC belong to TCTCTCGCCATGTGATCTCTGCACACGCCGGCTCCCCTTCGCC TTCCGCCATGAGTGGAAGCAGCCTGAGGCCCTCACCAGAAGCAGA MSTB1 TGCTGGCGCCATGCTTCTTGTACAGCCTGCAGAACCGTGAGCCAA subfamily ATAAACCTCTTTTCTTTATAAATTACCCAGCCTCAGGTATTCCTTTA TAGCAACACAAAACGGACTAAGACA113 TGCTATGGTTTGGATATGGTTTGTTTGTCCCCACCAAAACTCATGTT Consensus GAAATTTGATCCCCAATGTGGCGGTGTTGGGAGGTGGGGCCTA sequence for GTGGGAGGTGTTTGGGTCATGGGGGCGGATCCCTCATGAATGGCT transposable TGGTGCCGTTCTCGCGGTAGTGAGTGAGTGAGTTCTCGCTCTCGC elements that GAGACTGGATTAGTTCTCGCGGGAATGGATTAGTTCCCGCGAGAG belong to TGGGTTGTTATAAAGCCAGGACGCCCCTCGGGTTTTGCCTCTTCG CACGTGTCCGCTTCCCCTTTGACCTTCTCCGCCATGTTNTGACGCA MSTB2 GCACGAAAGCCCTCACCAGAAGCCAGGGCCATGCCCTTGAACTT subfamily CCCAGCCTGCAGAACCGTGAGCTAAATAAACCTCTTTTCTTTATAA ATTACCCAGTCTCAGGTATTCTGTTATAGCAACACAAAACGGAC TAAGACA114 TGCTATGGTTTGAATGTTTGTCCCCTCCAAAACTCATGTTGAAACT Consensus TAATCCCCAATGTGGCAGTATTGAGAGGTGGGGCCTTTAAGAGG sequence for TGATTGGGTCATGAGGGCTCTGCCCTCATGAATGGATTAATCCATT transposable CATGGATTAATGGATTAATGGATTAATGGGTTATCATGGGAGTG elements that GGACTGGTGGCTTTATAAGAAGAGGAAGAGAGACCTGAGCTAGCA belong to CGCTCAGCCCCCTCGCCATGTGATGCCCTGCGCCGCCTCGGGACT CTGCAGAGAGTCCCCACCAGCAAGAAGGCCCTCACCAGATGCGGC MSTC CCCTCGACCTTGGACTTCTCAGCCTCCANAACTGTAAGAAATAAA subfamily TTCCTTTTCTTTATAAATTACCCAGTTTCAGGTATTCTGTTATAAGC AACAGAAAACGGACTAAGACA115 TGCTATGGTTTGAATGTGTCCCCCAAAGTTCATGTGTTGGAAACTT Consensus AATCCCCAATGCAACAGTGTTGGGAGGTGGGGCCTNNTAAGAGG sequence for TGATTAGGTCATGAGGGCTCCGCCCTCATGAATGGATTAATGCCGT transposable TATCGCGGGAGTGGGTTAGTTATCGCGGGAGTGGGTTCGTTATA elements that AAAGNAAGTTCGGCCCCCTTTTGCTCTCTCTCTCTCGCTCTCTTGCC belong to CTTCCGCCTTCCGCCATGGGATGACGCAGCAAGAAGGCCCTCGCCAGATGCCGGCNCCTCGATCTTGGACTTCCCAGCCTCCAGAACCGAttorney Docket No. 60448-717.601SEQ SequencesIDNoTGAGCCAAATAAATTTCTGTTCTTTATAAATTACCCAGTCTGTG MSTD GTATTCTGTTATAGCAGCACAAAACGGACTAAGACA subfamily 116 GTAAATTGGTACCAGTAGAGTGGGGCGCTGCTGAAAAGATACCCG Consensus AAAATGTGGAAGCGACTTTGGAACTGGGTAACAGGCAGAGGTTGG sequence for AACAGTTTGGAGGGCTCAGAAGAAGACAGGAAAATGTGGGAAAG transposable TTTGGAACTTCCTAGAGACTTGTTGAATGGCTTTGACCAAAATGCT elements that GATAGTGATATGGACAATAAAGTCCAGGCTGAGGTGGTCTCAGAT belong to GGAGATGAGGAACTTGTTGGGAACTGGAGCAAAGGTGACTCTTGT TATGTTTTAGCAAAGAGACTGGCGGCATTTTGCCCCTGCCCTAGAG THEl-int ATTTGTGGAACTTTGAACTTGAGAGAGATGATTTAGGGTATCTG subfamily GCGGAAGAAATTTCTAAGCAGCAAAGCATTCAAGAGGTGACTTGG GTGCTGTTAAAGGCATTCAGTTTTANAAGGGAAGCAGAGCATAAA AGTTCGGAAAATTTGCAGCCTGACGATGCGATAGAAAAGAAAANC CCATTTTCTGAGGAGAAATTCAAGCCGGCTGCAGAAATTTGCATA AGTAACGAGGAGCCGAATGTTAATCCCCAAGACAATGGGGAAAAT GTCTCCAGGGCATGTCAGAGGCCTTCGCGGCAGCCCCTCCCATCA CAGGCCCGGAGGCCTAGGAGGAAAAAATGGTTTCGTGGGCCGGGC CCAGGGTCCCCGTGCTGTGTGCAGCCTAGGGACTTGGTGCCCTGC GTCCCAGCCGCTCCAGCCGTGGCTGAAAGGGGCCAACGTACAGCT CGGGCCGTGGCTTCAGAGGGTGCAAGCCCCAAGCCTTGGCAGCTT CCACGTGGTGTTGAGCCTGCGGGTGCACAGAAGTCAAGAATTGAG GTTTGGGAACCTCCGCCTAGATTTCAGAGGATGTATGGAAACGCC TGGATGCCCAGGCAGAAGTTTGCTGCAGGGGCGGGGCCCTCATGG AGAACCTCTGCTAGGGCAGTGCGGAAGGGAAATGTGGGGTCGGAG CCCCCACACAGAGTCCCTACTGGGGCACCGCCTAGTGGAGCTGTG AGAAGAGGGCCACCGTCCTCCAGACCCCAGAATGGTAGATCCACC GACAGCTTGCACCGTGCGCCTGGAAAAGCCGCAGACACTCAACGC CAGCCCGTGAAAGCAGCCGGGAGGGAGGCTGTACCCTGCAAAGCC ACAGGGGCGGAGCTGCCCAAGACCATGGGAACCCACCTCTTGCAT CAGCGTGACCTGGATGTGAGACATGGAGTCAAAGGAGATCATTTT GGAGCTTTAAGATTTGACTGCCCCGCTGGATTTCGGACTTGCATGG GGCCTGTAGCCCCTTTGTTTTGGCCAATTTCTCCCATTTGGAAT GGCTGTATTTACCCAATGCCTGTACCCCCATTGTATCTAGGAAGTA ACTAACTTGCTTTTGATTTTACAGGCTCATAGGCGGAAGGGACT TGCCTTGTCTCAGATGAGACTTTGGACTGTGGACTTTTGAGTTAAT GCTGAAATGAGTTAAGACTTTGGGGGACTGTTGGGAAGGCATGA TTGGTTTTGAAATGTGAGGACATGAGATTTGGGAGGGGCCAGGGG CGGAA117 TGATATGGTTTGGCTGTGTCCCCACCCAAATCTCAACTTGAATTGT Consensus ATCTCCCAGAATTCCCACGTGTTGTGGGAGGGACCCAGGGGGAG sequence for GTAATTGAATCATGGGGGCCGGTCTTTCCCGTGCTATTCTCGTGAT transposable AGTGAATAAGTCTCACGAGATCTGATGGGTTTATCAGGGGTTTC elements that CGCTTTTGCTTCTTCCTCATTTTCCTCTTGCCGCCGCCATGTAAGAA belong to GTGCCTTTCGCCTCCCGCCATGATTCTGAGGCCTCCCCAGCCA TGTGGAACTGTAAGTCCAATTAAACCTCTTTTTCTTCCCAGTCTCG THE1A GGTATGTCTTTATCAGCAGCGTGAAAACGGACTAATACA subfamily 118 TGATATGGTTTGGCTGTGTCCCCACCCAAATCTCATCTTGAATTGT Consensus AGCTCCCATAATTCCCACGTGTCGTGGGAGGGACCCGGTGGGAG sequence for GTAATTGAATCATGGGGGCGGGTCTTTCCCGTGCTGTTCTCGTGAT transposable AGTGAATAAGTCTCACGAGATCTGATGGTTTTATAAAGGGGAGT elements that TCCCCTGCACANGCTCTCTTGCCTGCCGCCATGTAAGACGTGNCTT belong toTGCTCCTCCTTCGCCTTCCGCCATGATTGTGAGGCCTCCCCAGCAttorney Docket No. 60448-717.601SEQ SequencesIDNoCACGTGGAACTGTGAGTCCATTAAACCTCTTTCCTTTATAAATTAC THE1B CCAGTCTCGGGTATGTCTTTATCAGCAGCGTGAAAACGGACTAA subfamily TACA119 TGATATGGTTTGGCTGTGTCCCCACCCAAATCTCATCTTGAATTGT Consensus AGTTCCCATAATCCCCACGTGTCGTGGGAGGGACCCGGTGGGAG sequence for GTAATTGAATCATGGGGGCGGTTACCCCCATGCTGTTCTCGTGATA transposable GTGAGTGAGTTCTCACGAGATCTGATGGTTTTATAAGGGGCTTT elements that TCCCCCTTCGCTCGGCACTTCTCCTTCCTGCCGCCATGTGAAGAAG belong to GACGTGTTTGCTTCCCCTTCCGCCATGATTGTAAGTTTCCTGAG GCCTCCCCAGCCATGCNGAACTGTGAGTCAATTAAACCTCTTTCCT THE1C TTATAAATTACCCAGTCTCGGGTATGTCTTTATTAGCAGCGTGA subfamily GAACGGACTAATACA120 TGATATGGTTTGGCTGTGTCCCCACCCAAANTCTCATCTCGAATTG Consensus TAATCCCCATAATCCCCACGTGTCGAGGGAGGGACCTGGTGGAG sequence for GTGATTGGATCATGGGGGCGGTTTCCCCCATGCTGTTCTCGTGATA transposable GTGAGTGAGTTCTCACGAGATCTGATGGTTTTATAAGTGTCTGG elements that CAGNTTTCCCCTGCNCTCACNCTTCTCTCTCCTGCCGCCNTGTGAA belong to GAAGGTGCTTGCTTCCCCTTCGCCTTCCGCCATGATTGTAAGTT TCCTGAGGCCTCCCCAGCCATGCGGAACTGTGAGTCAATTAAACCT THE1D CTTTCCTTTATAAATTACCCAGTCTCGGGTAGTTCTTTATAGCA subfamily GTGTGAAAACGGACTAATACA121 GAAAATTGGTACCGGGAGAGTGGGGCACTGCTATAAAGATACCTG Consensus AAAATGTGGAAGCGACTTTGGAACTGGGTAACGGGCAGAGGTTGG sequence for AACAGTTTGGAGGGCTCAGAAGAAGACAGGAAGATGTGGGAAAG transposable TTTGGAACTTCCTAGAGACTTGTTGAATGGTTTTGACCAAAATGCT elements that GATAGTGATATGGACAATGAAGTCCAGGCTGAGGTGGTCTCAGAT belong to GGAGATGAGGAACTTATTGGGAACTGGAGTAAAGGTCACTCTTGC TATGCTTTAGCAAAGAGACTGGCGGCATTTTGCCCCTGCCCTAGAG THElD-int ATCTGTGGAACTTTGAACTTGAGAGAGATGATTTAGGGTATCTG subfamily GCGGAAGAAATTTCTAAGCAGCAAAGCATTCAAGATGTGACCTGG CTGCTTCTAAAAGCGTACGGTCATATGCGTTCACAAAGAGATGGT CTGAAATTGGAACTTATGTTTAAAAGGGAAGCAGAGCATAAAAGT TTGGAAAATTTGCAGCCTGACCATGCGGTAGAAAAGAAAAACCCA TTTTCTGGGGAGAAATTCAAGCCGGCTGCAGAAATTTGCATAAGT AACGAGGAGCCGAATGTTAATAGCCAAGACAATGGGGAAAATGTC TCCAGGGCATNTCAGAGACCTTCGCGGCAGCCCCTCCCATCACAG GCCCGGAGGCCTAGGAGGGAAAAATGGTTTCGTGGGCCGGGCCCA GGGCCCCGCTGCTCTGTGCAGCCTCGGGACATGGCGCCCTGCGTCC CAGCCGCTCCAGCTCCAGCCGTGGCTAAAAGGGGCCAAGGTACA GCTCGGGCCGTTGCTTCAGAGGGTGCAAGCCCCAAGCCTTGGCGG CTTCCACGTGGTGTTGGGCCTGCGGGTGCGCAGAAGNCAAGAGTT GAGGTTTGGGAACCTCCGCCTAGATTTCAGAGGATGTATGGAAAC GCCTGGATGTCCAGGCAGAAGTCTGCTGCAGGGGCGGAGCCCTCA TGGAGAACCTCTGCTAGGGCAGTGCGGAGGGGAAATGTGGGGTTG GAGCCCCCACACAGAGTCCCCACTGGGGCACTGCCTAGTGGAGCT GTGAGAAGAGGGCCACCGTCCTCCAGACCCCAGAATGGTAGATCC ACCGACAGCTTGCACCGTGCGCCTGGAAAAGCCGCAGGCACTCAA CGCCAGCCCGTGAAAGCAGCCGCGGGGGCTGTACCCTGCAGAGCC ACAGGGGCGGAGCTGCCCAAGGCCNTGGGAGCCCACCCCTTGCAT CAGCGTGNCCTGGATGTGAGACATGGAGTCAAAGGAGATTATTTT GGAGCTTTAAGATTTAATGACTGCCCTGCTGGGTTTCGGACTTGC ATGGGGCCTGTAGCCCCTTTGTTTTGGCCAATTTCTCCCATTTGGA ATGGGAGCATTTACCCAATGCCTGTACCCCCATTGTATCTTGGAAGTAACTAACTTGCTTTTGATTTTACAGGCTCATAGGCGGAAGGGAAttorney Docket No. 60448-717.601SEQ SequencesIDNoCTTGCCTTGTCTCAGATGAGACTTTGGACTTGGACTTTTGAGTT AATGCTGGAATGAGTTAAGACTTTGGGGGACTGTTGGGAAGGCAT GATTGTGTTTTGAAATGTGAGAAGGACATGAGATTTGGGAGGGGCCAGGGGCGGAATable 2. Genomic positions of a list of integrants that belong to LTR16C subfamily Clir Start End Strand Clir Start End Strand Clir Start End Strand 40736 40878 - clirl 9 6988164 6988 chr4 24198 2419 clirl 399 + 639 8810 - 836414 836851 + clirl 9 7641434 7641 chr4 24356 2435 clirl 674 - 970 7276 + clirl 2223082 2223263 + clir 19 7739334 7739 - chr4 24477 2447 - 560 337 7781 clirl 2223722 2223767 + clir 19 7771351 7771 + chr4 24507 2450 - 570 529 7818 clirl 4285609 4285801 - clirl 9 7883410 7883 + chr4 24666 2466 +510 854 7206 clirl 5768693 5768829 + clir 19 8545814 8546 + chr4 24978 2497 - 056 953 9409 clirl 6941475 6941619 - clirl 9 8546979 8547 + chr4 25942 2594 + 015 543 2804 clirl 7245757 7246110 - clirl 9 8547621 8547 + chr4 25968 2596 +740 344 8750 clirl 9520553 9520801 + clir 19 9864954 9865 + chr4 26023 2602 - 039 780 4006 clirl 10869022 10869253 - clirl 9 9962989 9963 + chr4 26059 2605 - 205 494 9885 clirl 11580502 11580771 + clir 19 1127975 1127 + chr4 26060 2606 - 4 9861 271 0358 clirl 11850603 11850689 - clirl 9 1130017 1130 - chr4 26577 2657 - 9 0421 564 7795 clirl 11851949 11852186 - clirl 9 1130045 1130 - chr4 26809 2680 - 1 0535 534 9734 clirl 11852489 11852517 - clirl 9 1324786 1324 + chr4 26810 2681 +5 8184 004 0347 clirl 11852835 11853011 - clirl 9 1330500 1330 - chr4 27131 2713 - 1 5406 103 1492 clirl 12090793 12090823 - clirl 9 1335460 1335 - chr4 27223 2722 - 4 4642 481 3803 clirl 12091215 12091514 - clirl 9 1335544 1335 - chr4 29133 2913 +3 5646 476 3546 clirl 14415588 14415858 + clir 19 1336450 1336 + chr4 29134 2913 + 0 4625 050 4081 clirl 14435349 14435644 + clir 19 1336494 1336 + chr4 30217 3021 + 0 5137 557 7654 clirl 14445656 14445848 - clirl 9 1337342 1337 + chr4 30217 3021 +8 3717 667 7735 clirl 14685052 14685515 - clirl 9 1343903 1343 + chr4 30217 3021 +9 9108 775 7899 clirl 14765980 14766276 - clirl 9 1343935 1343 + chr4 30257 3025 - 2 9386 958 8185 clirl 14833295 14833561 - clirl 9 1344213 1344 - chr4 30677 3067 - 0 2455 052 7163 clirl 17003049 17003267 + clir 19 1352652 1352 + chr4 30679 3067 - 1 6926 451 9731 clirl 17295845 17296296 + clir 19 1355952 1355 - chr4 31918 3191 +7 9920 347 8561 clirl 17703050 17703247 - clirl 9 1356029 1356 + chr4 32178 3217 +8 0627 064 8285Attorney Docket No. 60448-717.601clirl 17843620 17843770 + clirl 9 1361795 1361 + chr4 32788 3278 - 7 8094 058 8194 clirl 18061544 18062005 + clirl 9 1364351 1364 - chr4 32789 3278 - 4 3968 123 9222 clirl 18139728 18139957 + clirl 9 1364736 1364 - chr4 33408 3340 +8 7426 324 8616 clirl 18140224 18140456 + clirl 9 1369380 1369 - chr4 35974 3597 - 1 4258 084 4442 clirl 18174525 18174900 + clirl 9 1369680 1369 - chr4 36552 3655 +6 7193 845 3253 clirl 18261782 18261984 - clirl 9 1370517 1370 + chr4 37714 3771 - 2 5361 389 4608 clirl 18262151 18262280 - clirl 9 1394142 1394 - chr4 37714 3771 - 6 1516 690 4800 clirl 18295699 18295892 + clirl 9 1404848 1404 + chr4 38795 3879 - 0 8917 627 6011 clirl 18296122 18296253 + clirl 9 1423731 1423 - chr4 40650 4065 +6 7697 182 0427 clirl 18387620 18387852 - clirl 9 1430683 1430 + chr4 42927 4292 - 9 6962 819 8105 clirl 18404435 18404551 + clirl 9 1430727 1430 + chr4 43352 4335 +4 7463 020 2437 clirl 18405020 18405277 + clirl 9 1430784 1430 + chr4 44524 4452 - 7 7915 156 4624 clirl 18490539 18490722 + clirl 9 1433983 1434 + chr4 46345 4634 +6 0105 338 5753 clirl 18499017 18499144 - clirl 9 1434547 1434 + chr4 46944 4694 +4 5733 311 4553 clirl 18499927 18500136 - clirl 9 1461530 1461 + chr4 47732 4773 +1 5428 442 2565 clirl 18976205 18976553 - clirl 9 1461592 1461 + chr4 47732 4773 +5 5966 863 2981 clirl 20359630 20359650 - clirl 9 1461627 1461 + chr4 48094 4809 - 0 6379 525 4824 clirl 20359762 20360140 - clirl 9 1462657 1462 - chr4 52134 5213 +4 7049 200 4677 clirl 20360432 20360525 - clirl 9 1464833 1464 + chr4 52570 5257 - 3 8555 059 0341 clirl 21582945 21583283 - clirl 9 1465076 1465 + chr4 52918 5291 - 2 0848 778 8830 clirl 21858681 21859013 + clirl 9 1466227 1466 - chr4 52921 5292 +6 2393 810 2140 clirl 21966580 21966789 + clirl 9 1507804 1507 + chr4 53946 5394 - 7 8125 641 6926 clirl 22230295 22230598 - clirl 9 1507820 1507 + chr4 54553 5455 - 3 8486 344 3778 clirl 22314494 22314606 - clirl 9 1510148 1510 - chr4 55626 5562 - 5 1748 964 7087 clirl 22315150 22315514 - clirl 9 1514260 1514 - chr4 55657 5565 - 5 3000 597 7823 clirl 23409935 23410131 + clirl 9 1515399 1515 - chr4 57112 5711 - 2 4444 263 2416 clirl 24153209 24153434 + clirl 9 1515735 1515 - chr4 57237 5723 - 4 7691 003 7110 clirl 24157955 24158368 - clirl 9 1546752 1546 + chr4 57730 5773 +4 7785 587 0913 clirl 24973238 24973612 - clirl 9 1546777 1546 + chr4 57731 5773 +3 7838 484 1604 clirl 25040560 25040877 + clirl 9 1546792 1546 + chr4 58163 5816 - 4 7940 159 3562 clirl 25063721 25064178 - clirl 9 1546853 1546 + chr4 58556 5855 +9 8618 311 6392 clirl 25524398 25524799 - clirl 9 1552367 1552 - chr4 58556 5855 +4 3768 760 6954 clirl 25547065 25547201 - clirl 9 1552488 1552 - chr4 58735 5873 - 5 5087 725 5800 clirl 25547529 25547626 - clirl 9 1552803 1552 + chr4 58736 5873 -8 8158 080 6408Attorney Docket No. 60448-717.601clirl 26004373 26004579 + clirl 9 1552837 1552 + chr4 59309 5931 - 3 8681 992 0470 clirl 29343184 29343629 + clirl 9 1555689 1555 + chr4 59979 5997 +9 7220 196 9530 clirl 29446510 29446648 - clirl 9 1555721 1555 + chr4 60272 6027 - 1 7292 051 2443 clirl 29849253 29849656 - clirl 9 1559038 1559 + chr4 60399 6039 +6 0728 355 9398 clirl 30244552 30244818 + clirl 9 1586922 1586 - chr4 60860 6086 - 1 9514 625 0755 clirl 30447131 30447357 - clirl 9 1605069 1605 - chr4 60861 6086 - 2 0903 050 1332 clirl 30476464 30476633 - clirl 9 1606262 1606 + chr4 62853 6285 - 6 3062 500 3774 clirl 30476645 30476749 - clirl 9 1652610 1652 + chr4 62853 6285 - 1 6212 895 3952 clirl 30598765 30598837 - clirl 9 1679209 1679 - chr4 63375 6337 +3 2248 354 5803 clirl 31506570 31507022 - clirl 9 1758449 1758 - chr4 63623 6362 - 2 4609 224 3526 clirl 31849465 31849798 + clirl 9 1764680 1764 + chr4 63799 6379 - 1 7062 025 9489 clirl 31877693 31877942 + clirl 9 1783846 1783 - chr4 63894 6389 - 1 8516 304 4506 clirl 33186883 33187349 - clirl 9 1783901 1783 - chr4 63976 6397 +7 9205 112 6153 clirl 33192507 33192705 - clirl 9 1841293 1841 - chr4 65761 6576 - 5 3138 745 1856 clirl 33192719 33192763 - clirl 9 1898433 1898 - chr4 66737 6673 - 7 4489 976 8292 clirl 33894271 33894739 + clirl 9 1911602 1911 + chr4 66914 6691 +0 6303 963 5371 clirl 34056733 34057040 - clirl 9 2255191 2255 - chr4 67032 6703 - 6 2323 851 3193 clirl 34126092 34126251 + clirl 9 2815867 2815 - chr4 67036 6703 - 7 8818 681 6973 clirl 34433492 34433901 - clirl 9 2815910 2815 - chr4 69623 6962 - 9 9152 317 3483 clirl 34484020 34484374 + clirl 9 2819340 2819 - chr4 69683 6968 +5 3853 822 3988 clirl 34531907 34532351 - clirl 9 2823135 2823 - chr4 71650 7165 +8 1716 206 0622 clirl 34750175 34750594 - clirl 9 2825081 2825 - chr4 72143 7214 +8 1200 669 3907 clirl 34826422 34826947 - clirl 9 2829319 2829 - chr4 72144 7214 +1 3452 477 4534 clirl 35789257 35789614 - clirl 9 2830378 2830 + chr4 72956 7295 - 6 4111 717 6899 clirl 36566187 36566669 + clirl 9 2833287 2833 + chr4 72956 7295 - 4 3125 912 7024 clirl 36639694 36639843 - clirl 9 2833349 2833 + chr4 73352 7335 +1 3688 445 2636 clirl 36679620 36679872 + clirl 9 2837416 2837 + chr4 73478 7347 +7 4608 373 8625 clirl 36688178 36688300 - clirl 9 2839528 2839 - chr4 73932 7393 +8 5343 211 2290 clirl 36689033 36689318 - clirl 9 2839560 2839 - chr4 73932 7393 +7 5661 265 2429 clirl 36789511 36789946 + clirl 9 2839596 2839 - chr4 74126 7412 +1 5971 004 6112 clirl 36987323 36987644 - clirl 9 2839626 2839 - chr4 75160 7516 - 1 6356 775 1121 clirl 37001695 37001988 - clirl 9 2839684 2839 - chr4 75425 7542 +0 6907 297 5566 clirl 38058980 38059437 - clirl 9 2839698 2839 - chr4 75890 7589 +9 7079 792 0900 clirl 38208681 38208888 + clirl 9 2848919 2848 - chr4 75891 7589 +6 9402 211 1490Attorney Docket No. 60448-717.601clirl 38209113 38209301 + clirl 9 2850055 2850 + chr4 76448 7644 +7 1022 367 8453 clirl 38245010 38245343 - clirl 9 2857497 2857 - chr4 76448 7644 +6 5141 474 8766 clirl 38673377 38673600 - clirl 9 2857656 2857 - chr4 77140 7714 - 7 6788 750 0830 clirl 38755490 38755656 + clirl 9 2859432 2859 + chr4 77232 7723 - 8 4381 197 2381 clirl 38756222 38756320 + clirl 9 2886671 2886 - chr4 77290 7729 - 7 7132 250 0423 clirl 40438372 40438812 - clirl 9 2890398 2890 + chr4 77420 7742 - 3 4228 661 0724 clirl 40965122 40965283 - clirl 9 2891235 2891 - chr4 77420 7742 - 6 2661 791 0972 clirl 41271018 41271483 - clirl 9 2899477 2899 - chr4 77482 7748 +5 4972 582 2751 clirl 41464220 41464558 + clirl 9 2903883 2903 + chr4 77490 7749 - 5 9190 147 0479 clirl 41464960 41465033 + clirl 9 2903959 2903 + chr4 77563 7756 +5 9740 482 3530 clirl 41467665 41467964 - clirl 9 2913012 2913 - chr4 77624 7762 - 6 0412 154 4266 clirl 42220509 42220870 + clirl 9 2913093 2913 - chr4 77642 7764 - 4 1110 261 2534 clirl 42392455 42392676 + clirl 9 2937330 2937 - chr4 78621 7862 +9 3758 460 1836 clirl 42393013 42393251 + clirl 9 2942907 2942 + chr4 79189 7918 +0 9453 540 9783 clirl 42824525 42824995 - clirl 9 2950209 2950 - chr4 79455 7945 - 6 2342 876 6324 clirl 43018622 43019106 - clirl 9 2958092 2958 - chr4 80143 8014 +9 1117 189 3252 clirl 43507201 43507673 - clirl 9 2958147 2958 - chr4 80144 8014 +0 1793 850 4998 clirl 44459932 44460364 - clirl 9 2963160 2963 - chr4 81276 8127 - 5 1801 456 6635 clirl 45262011 45262393 + clirl 9 2967330 2967 + chr4 81347 8134 - 1 3391 722 8018 clirl 48251474 48251922 + clirl 9 2967354 2967 + chr4 82055 8205 - 8 3670 505 5795 clirl 48495563 48495993 - clirl 9 2988748 2988 + chr4 82144 8214 +5 7770 429 4858 clirl 48512608 48513071 + clirl 9 3009564 3009 - chr4 82193 8219 - 7 6065 035 3374 clirl 48699417 48699876 + clirl 9 3012391 3012 - chr4 82770 8277 +8 4042 648 0953 clirl 48859217 48859584 + clirl 9 3030381 3030 + chr4 82771 8277 +6 4214 257 1399 clirl 50285539 50285881 - clirl 9 3058955 3058 - chr4 83643 8364 - 4 9876 657 3831 clirl 50372782 50373229 + clirl 9 3067270 3067 - chr4 84181 8418 - 3 2987 736 2109 clirl 50398182 50398475 - clirl 9 3067451 3067 - chr4 85514 8551 +6 4638 182 4375 clirl 50411846 50411941 - clirl 9 3085815 3085 + chr4 85514 8551 - 0 8522 855 5090 clirl 51073303 51073650 - clirl 9 3099629 3099 - chr4 86293 8629 +6 6645 471 3543 clirl 51603779 51604210 - clirl 9 3125792 3125 - chr4 86293 8629 +8 8325 958 4343 clirl 52638522 52638930 - clirl 9 3126421 3126 + chr4 86506 8650 - 8 4519 533 6736 clirl 54019196 54019503 - clirl 9 3139948 3139 + chr4 87230 8723 +1 9711 972 1406 clirl 54019797 54019949 - clirl 9 3143235 3143 + chr4 87493 8749 +1 2519 093 3214 clirl 54116284 54116772 - clirl 9 3143669 3143 + chr4 87718 8771 -3 6882 179 8588Attorney Docket No. 60448-717.601clirl 54141728 54141979 - clirl 9 3143726 3143 + chr4 87859 8785 +8 7495 290 9653 clirl 54154920 54155345 - clirl 9 3179711 3179 - chr4 88077 8807 - 4 7550 981 8354 clirl 54167457 54167813 + clirl 9 3201575 3201 + chr4 88925 8892 - 6 5946 967 6269 clirl 54513350 54513530 - clirl 9 3201714 3201 + chr4 90980 9098 +3 7246 910 1342 clirl 54774658 54774983 - clirl 9 3333918 3333 - chr4 91314 9131 - 6 9641 842 5150 clirl 54845389 54845735 + clirl 9 3382680 3382 + chr4 91315 9131 - 1 6951 181 5334 clirl 55419008 55419192 - clirl 9 3382797 3382 + chr4 91407 9140 - 3 8128 897 8067 clirl 55419300 55419425 - clirl 9 3588701 3588 - chr4 91845 9184 +5 7404 541 5665 clirl 55744158 55744481 + clirl 9 3600303 3600 + chr4 91849 9184 +9 3198 095 9281 clirl 55832186 55832621 + clirl 9 3750599 3750 + chr4 91985 9198 - 8 6297 361 5571 clirl 55990447 55990626 - clirl 9 3929267 3929 - chr4 93299 9329 - 1 2803 032 9136 clirl 55990619 55990713 - clirl 9 3929322 3929 - chr4 95251 9525 +9 3505 373 1424 clirl 56093459 56093913 + clirl 9 4068319 4068 + chr4 95634 9563 +3 3549 891 5226 clirl 56135812 56136231 - clirl 9 4455570 4455 - chr4 95798 9579 +7 5757 795 9196 clirl 57207993 57208266 - clirl 9 4455595 4455 - chr4 96124 9612 +1 6093 685 4999 clirl 58037049 58037358 + clirl 9 4455640 4455 - chr4 96990 9699 - 6 6518 437 0734 clirl 58037712 58037885 + clirl 9 4462312 4462 - chr4 97228 9722 - 9 3523 836 8938 clirl 58204434 58204750 - clirl 9 4742417 4742 + chr4 97228 9722 - 4 4296 938 9206 clirl 58368671 58368828 + clirl 9 4742460 4742 + chr4 97653 9765 - 5 4733 755 4194 clirl 58369022 58369323 + clirl 9 4815434 4815 + chr4 98695 9869 - 6 4662 392 5437 clirl 58382017 58382072 + clirl 9 5734043 5734 + chr4 98695 9869 - 2 0563 735 5814 clirl 58440812 58441251 clirl KI 121274 1214 + chr4 98696 9869270708v 90 282 6660 1 randomclirl 58455070 58455523 clirl KI 37265 3735 chr4 99200 9920270712v 5 503 0566 1 randomclirl 58556319 58556776 clirl KI 128798 1292 + chr4 99200 9920 - 270759v 43 590 0805 1 altclirl 59960086 59960416 clirl KI 100058 1002 - chr4 10087 1008 - 270760v 84 4975 7519 1 alt 8 clirl 60098986 60099321 + clir2 3443282 3443 + chr4 10182 1018 - 394 3928 24369 clirl 60653875 60654288 - clir2 4231761 4232 - chr4 10375 1037 - 204 7923 58042Attorney Docket No. 60448-717.601clirl 60796393 60796470 + chr2 5598083 5598 + chr4 10429 1042 - 458 3052 93293 clirl 60796620 60796814 + chr2 6967511 6967 + chr4 10509 1050 +797 4351 94645 clirl 61178774 61179097 - chr2 7195333 7195 + chr4 10560 1056 - 808 1375 01824 clirl 63080493 63080923 - chr2 8509836 8509 + chr4 10774 1077 - 952 2404 42558 clirl 63688954 63689370 - chr2 8510810 8510 + chr4 10774 1077 - 919 2853 43176 clirl 63751116 63751552 + chr2 1095461 1095 + chr4 10818 1081 +7 4833 8893 89371 clirl 64347861 64348227 + chr2 1096450 1096 + chr4 10846 1084 - 4 4751 8010 68484 clirl 65091638 65091876 + chr2 1206453 1206 + chr4 10900 1090 +8 4706 8187 08529 clirl 65092710 65092921 + chr2 1206515 1206 + chr4 10938 1093 - 7 5278 6113 86440 clirl 65137927 65137966 + chr2 1224406 1224 - chr4 10939 1093 - 7 4371 3859 94324 clirl 65138034 65138312 + chr2 1299420 1299 - chr4 11540 1154 - 7 4263 7936 08308 clirl 66864448 66864540 - chr2 1299461 1299 - chr4 11544 1154 +8 5028 2107 42588 clirl 67143328 67143732 - chr2 1419291 1419 + chr4 11602 1160 +4 2997 4938 25404 clirl 67835795 67836088 + chr2 1419303 1419 + chr4 11621 1162 - 1 3159 2508 12752 clirl 67935539 67935596 - chr2 1429799 1429 - chr4 11621 1162 - 7 8143 7746 18013 clirl 67936070 67936485 - chr2 1486924 1486 + chr4 11638 1163 - 6 9492 9303 89598 clirl 68119626 68119775 + chr2 1509703 1509 - chr4 11732 1173 +7 7220 2982 23111 clirl 69122639 69123098 - chr2 1510670 1510 - chr4 11790 1179 +0 7000 0325 00593 clirl 69707141 69707580 + chr2 1512334 1512 - chr4 11790 1179 +9 3390 1064 01168 clirl 69832043 69832462 - chr2 1512640 1512 - chr4 11793 1179 - 7 6767 0450 30642 clirl 70821317 70821470 - chr2 1538919 1538 + chr4 11795 1179 +5 9369 7695 58180 clirl 70821514 70821638 - chr2 2091462 2091 + chr4 11947 1194 +1 4786 5049 75463 clirl 70908358 70908673 + chr2 2091480 2091 + chr4 12008 1200 +0 4884 7880 87993Attorney Docket No. 60448-717.601clirl 71202711 71203153 - chr2 2172070 2172 - chr4 12052 1205 - 6 1190 6074 26154 clirl 72845982 72846345 + chr2 2230210 2230 - chr4 12152 1215 - 2 2412 4010 24417 clirl 72966692 72967149 - chr2 2346429 2346 + chr4 12216 1221 - 5 4612 3117 63571 clirl 73170231 73170647 - chr2 2565508 2565 + chr4 12358 1235 - 2 5126 2278 82665 clirl 73173934 73174083 - chr2 2565577 2565 + chr4 12401 1240 +9 6161 9897 20154 clirl 73754287 73754608 - chr2 2589947 2589 + chr4 12513 1251 +4 9692 4807 35078 clirl 73872091 73872263 + chr2 2590059 2590 + chr4 12582 1258 - 4 0644 8211 28344 clirl 73890837 73891014 - chr2 2590093 2590 + chr4 12588 1258 +4 1055 9642 89875 clirl 75569799 75570269 - chr2 2796710 2796 - chr4 12589 1258 +0 7169 0794 90924 clirl 75864806 75865237 + chr2 2796931 2796 - chr4 12594 1259 +9 9634 0063 40271 clirl 76151441 76151674 - chr2 2993979 2994 - chr4 12661 1266 +4 0242 0838 11216 clirl 76151667 76151794 - chr2 2998784 2998 + chr4 12672 1267 +9 8208 7802 28095 clirl 76784109 76784295 - chr2 3008703 3008 + chr4 12681 1268 - 0 7261 6755 17076 clirl 76784343 76784461 - chr2 3008741 3008 + chr4 12721 1272 - 7 7611 0395 10489 clirl 76858199 76858653 + chr2 3037728 3037 + chr4 12756 1275 +2 7755 1936 62240 clirl 79140771 79141192 - chr2 3473627 3473 - chr4 12835 1283 +1 6329 6467 56901 clirl 79468139 79468421 + chr2 3733204 3733 - chr4 12899 1289 +7 2174 2377 92849 clirl 79570114 79570570 - chr2 4118279 4118 - chr4 12939 1293 +6 3241 1012 91369 clirl 80173056 80173120 - chr2 4157244 4157 + chr4 12939 1293 +9 2707 1951 91969 clirl 80173116 80173221 - chr2 4677990 4678 + chr4 12939 1293 +0 0291 3751 93872 clirl 80973705 80973928 + chr2 4974858 4974 - chr4 12974 1297 - 9 8709 7620 48066 clirl 81006485 81006797 + chr2 4991441 4991 + chr4 13131 1313 +5 4839 1913 12183 clirl 81597808 81598049 - chr2 5108213 5108 + chr4 13414 1341 - 3 2576 7772 48186Attorney Docket No. 60448-717.601chr1 81634951 81635331 + chr2 5215704 5215 + chr4 13441 1344 - 9 7119 2857 13251 chr1 82570834 82571043 - chr2 5309653 5309 + chr4 13444 1344 - 3 6587 7170 47358 chr1 82806025 82806310 - chr2 5309660 5309 + chr4 13489 1348 - 3 6751 3615 94038 chr1 83066401 83066790 + chr2 5615165 5615 - chr4 13506 1350 - 6 2067 5724 66023 chr1 83068727 83068797 + chr2 5718316 5718 + chr4 13527 1352 +7 3243 8143 78352 chr1 83206253 83206528 + chr2 5756340 5756 - chr4 13527 1352 +2 3784 8411 78526 chr1 83206543 83206660 + chr2 5843454 5843 - chr4 13555 1355 +8 4998 2528 52800 chr1 83218095 83218416 - chr2 5954805 5954 - chr4 13609 1360 - 6 8431 5370 95656 chr1 83306396 83306687 + chr2 5971734 5971 + chr4 13702 1370 - 5 7537 5574 25959 chr1 83486416 83486766 - chr2 6180801 6180 - chr4 14018 1401 - 0 8116 7388 87818 chr1 83970691 83971179 - chr2 6222778 6222 - chr4 14055 1405 - 5 8015 7242 57373 chr1 85188503 85188763 - chr2 6431948 6431 - chr4 14055 1405 - 0 9625 8539 58801 chr1 85188791 85188906 - chr2 6431992 6432 - chr4 14098 1409 +4 0214 4590 85046 chr1 85292897 85293109 - chr2 6438005 6438 - chr4 14136 1413 +4 0468 9692 70096 chr1 86795756 86796207 - chr2 6440984 6441 - chr4 14156 1415 - 8 0326 0017 60466 chr1 87475151 87475444 + chr2 6548876 6548 - chr4 14157 1415 +2 9077 6768 77146 chr1 89275321 89275638 - chr2 6552464 6552 - chr4 14255 1425 +3 5088 3486 53822 chr1 90100541 90101030 + chr2 6717768 6717 - chr4 14384 1438 +8 7883 4641 45073 chr1 93716516 93716908 - chr2 6718683 6718 + chr4 14384 1438 +5 7129 5387 45427 chr1 94622672 94622918 - chr2 6800694 6800 - chr4 14396 1439 +4 7344 5632 66068 chr1 94630284 94630661 + chr2 7077178 7077 + chr4 14406 1440 +4 2105 8841 69274 chr1 94705789 94706239 + chr2 7116899 7116 + chr4 14406 1440 +2 9010 9587 69627 chr1 95534976 95535294 - chr2 7116957 7116 + chr4 14434 1443 - 1 9824 1607 42039Attorney Docket No. 60448-717.601chr1 95665312 95665469 + chr2 7125344 7125 - chr4 14481 1448 +7 3911 8495 18934 chr1 95666426 95666545 + chr2 7174119 7174 - chr4 14581 1458 +3 1512 4280 14606 chr1 96352050 96352437 + chr2 7184227 7184 + chr4 14581 1458 +8 2706 4964 15020 chr1 96414488 96414912 - chr2 7192730 7192 - chr4 14660 1466 - 0 7703 0318 00677 chr1 96989091 96989379 - chr2 7268822 7268 - chr4 14685 1468 +8 8529 3884 54252 chr1 97629229 97629355 - chr2 7268856 7268 - chr4 14759 1475 +3 8717 4244 94632 chr1 97629379 97629498 - chr2 7502051 7502 + chr4 14930 1493 +6 0609 6310 06609 chr1 98556546 98556834 - chr2 7502062 7502 + chr4 14931 1493 +1 0932 2676 13049 chr1 98574808 98574920 - chr2 7511983 7512 - chr4 14954 1495 +9 0064 9996 50409 chr1 99360529 99360986 - chr2 7512015 7512 - chr4 15053 1505 +1 0284 0501 30744 chr1 99432208 99432455 - chr2 7888034 7888 + chr4 15255 1525 - 7 0561 4655 54948 chr1 100335472 100335808 + chr2 7926609 7926 + chr4 15489 1548 +6 6544 0814 91148 chr1 100950786 100951243 - chr2 7983011 7983 - chr4 15593 1559 +8 0384 2652 32821 chr1 102232267 102232522 - chr2 8089019 8089 - chr4 15597 1559 - 1 0482 4882 75348 chr1 103296466 103296827 - chr2 8297402 8297 + chr4 15692 1569 - 2 4307 4544 24995 chr1 104149268 104149700 + chr2 8353415 8353 - chr4 15699 1569 +3 4469 1739 92065 chr1 106202142 106202554 - chr2 8404258 8404 + chr4 15954 1595 - 2 2912 5501 45686 chr1 106248339 106248512 - chr2 8406174 8406 - chr4 15988 1598 - 7 1790 5964 86035 chr1 106524246 106524490 + chr2 8406253 8406 - chr4 16051 1605 +0 2710 1739 11865 chr1 106525035 106525061 + chr2 8429297 8429 - chr4 16098 1609 +4 3262 9711 89922 chr1 107018924 107019363 - chr2 8429332 8429 - chr4 16099 1609 +2 3420 0371 90483 chr1 108126517 108126686 - chr2 8430926 8430 - chr4 16226 1622 - 5 9585 2861 63040 chr1 108126716 108126853 - chr2 8594728 8594 + chr4 16767 1676 +3 7747 1130 71273Attorney Docket No. 60448-717.601chr1 108328754 108329153 + chr2 8598721 8598 - chr4 16767 1676 +7 7460 1542 71652 chr1 110111287 110111466 + chr2 8832392 8832 - chr4 16769 1676 +5 4029 4437 94743 chr1 110111774 110112007 + chr2 8832433 8832 - chr4 16776 1677 - 9 4547 4883 65270 chr1 110728541 110728564 + chr2 8904274 8904 + chr4 16847 1684 +7 2952 3764 73834 chr1 110729554 110729610 + chr2 8904839 8904 + chr4 17099 1709 - 9 8454 8050 98167 chr1 110730432 110730807 + chr2 8904884 8904 + chr4 17198 1719 +5 8954 5018 85125 chr1 112139990 112140188 + chr2 8910306 8910 + chr4 17200 1720 - 2 3144 0333 00471 chr1 112239178 112239382 + chr2 8927031 8927 + chr4 17205 1720 - 2 0374 0131 50160 chr1 112239390 112239632 + chr2 8927967 8927 - chr4 17205 1720 - 0 9958 0837 51049 chr1 112661226 112661557 + chr2 8928890 8928 + chr4 17234 1723 - 4 9020 5681 46137 chr1 112772818 112773165 + chr2 8930145 8930 + chr4 17253 1725 - 0 1652 3937 34398 chr1 112790053 112790392 - chr2 8932177 8932 + chr4 17302 1730 - 6 2063 6108 26543 chr1 116347794 116347952 + chr2 8986054 8986 - chr4 17334 1733 - 3 0830 3898 44259 chr1 116852745 116852962 - chr2 8988082 8988 - chr4 17365 1736 +7 1029 3827 54216 chr1 118671714 118672193 - chr2 8989346 8989 - chr4 17572 1757 +4 3580 8716 29192 chr1 119782750 119783025 + chr2 8990258 8990 + chr4 17653 1765 +8 2876 0236 30426 chr1 120124098 120124500 + chr2 8991217 8991 - chr4 17675 1767 +2 2234 5200 55635 chr1 121414945 121415411 + chr2 9008001 9008 - chr4 17788 1778 - 9 0097 4576 84821 chr1 144083861 144083951 - chr2 9009747 9009 - chr4 17812 1781 - 0 7552 7635 27927 chr1 144876757 144876847 + chr2 9015163 9015 - chr4 17838 1783 - 7 1719 9094 89590 chr1 146285075 146285400 + chr2 9015211 9015 - chr4 17927 1792 - 0 2165 6591 76887 chr1 146285712 146285805 + chr2 9015760 9015 - chr4 17927 1792 - 6 7811 6955 76997 chr1 146746084 146746292 - chr2 9020726 9020 - chr4 18093 1809 - 2 7344 9735 39984Attorney Docket No. 60448-717.601chr1 146909616 146909895 + chr2 9031751 9031 + chr4 18111 1811 - 3 7765 4512 14952 chr1 148187134 148187413 - chr2 9148486 9148 - chr4 18140 1814 +0 5112 6759 06970 chr1 148735858 148736183 + chr2 9181584 9181 - chr4 18182 1818 +6 6098 9779 29996 chr1 148736495 148736588 + chr2 9203667 9203 + chr4 18293 1829 +2 6924 9827 39998 chr1 153343638 153343704 - chr2 9426721 9426 + chr4 18374 1837 +1 7463 8500 48560 chr1 153344273 153344466 - chr2 9475820 9475 - chr4 18374 1837 +4 8284 9020 49365 chr1 153344507 153344638 - chr2 9475827 9475 - chr4 18507 1850 +6 8641 8060 78122 chr1 156632230 156632587 - chr2 9705814 9705 - chr4 18599 1859 +7 8411 4263 94423 chr1 156635222 156635387 - chr2 9732406 9732 + chr4 18839 1883 - 0 4405 5883 96278 chr1 156635683 156635774 chr2 9735606 9735 + chr4 97275 9744 +3 6401 GL3 483527vl_altchr1 159992222 159992688 + chr2 9738410 9738 chr4 15215 15260 4445 GL3 4 2083527vl_altchr1 164184098 164184554 chr2 9924012 9924 + chr4 54446 54854 0586 KI27 60789vl altchr1 165009360 165009759 + chr2 1001608 1001 - chr5 20454 2045 +39 6130 45 818 7chr1 165605418 165605551 - chr2 1007595 1007 + chr5 31455 3145 - 60 5963 45 792 2chr1 165796037 165796327 + chr2 1016920 1016 + chr5 33751 3375 +08 9217 54 609 0chr1 166009964 166010419 + chr2 1034628 1034 + chr5 40345 4034 - 87 6303 53 676 7chr1 166764404 166764859 + chr2 1034630 1034 + chr5 40709 4071 +49 6315 19 189 5chr1 166891214 166891645 + chr2 1045251 1045 - chr5 50936 5094 - 82 2526 79 096 2chr1 167502470 167502565 - chr2 1046000 1046 - chr5 58906 5890 +19 0029 58 876 4chr1 167503020 167503159 - chr2 1056362 1056 + chr5 60050 6005 +79 3654 97 280 3chr1 169741538 169741926 - chr2 1056774 1056 - chr5 97363 9736 +77 7760 18 4021Attorney Docket No. 60448-717.601chr1 170328508 170328968 - chr2 1056779 1056 - chr5 97364 9736 +57 7825 46 712 8chr1 170725336 170725770 + chr2 1056793 1056 + chr5 10114 1011 +95 7977 197 4427 1chr1 172779786 172780019 + chr2 1057310 1057 - chr5 12153 1215 +11 3143 028 3222 2chr1 172892662 172893025 + chr2 1057326 1057 - chr5 12688 1268 +26 3268 349 8607 7chr1 173436121 173436406 - chr2 1057330 1057 - chr5 12712 1271 - 67 3347 659 2905 2chr1 175304894 175305086 - chr2 1059537 1059 - chr5 12783 1278 - 50 5416 754 4035 9chr1 177228582 177228707 - chr2 1063422 1063 - chr5 13188 1318 +78 4246 777 8922 5chr1 181673014 181673186 - chr2 1069057 1069 - chr5 13215 1321 - 03 0594 530 5925 8chr1 181673327 181673478 - chr2 1073818 1073 - chr5 13648 1364 - 82 8201 278 8491 5chr1 185912541 185912690 + chr2 1073820 1073 - chr5 14082 1408 - 32 8222 483 2778 3chr1 186978713 186979180 - chr2 1091222 1091 - chr5 14985 1498 - 13 2242 087 5421 4chr1 187297347 187297775 + chr2 1120474 1120 + chr5 15134 1513 +73 4782 170 4335 5chr1 188092569 188092768 + chr2 1120482 1120 + chr5 15134 1513 +12 4830 541 4739 3chr1 188093828 188093897 + chr2 1124808 1124 - chr5 15160 1516 - 21 8119 870 0983 6chr1 188221718 188222158 - chr2 1125904 1125 - chr5 15203 1520 - 55 9081 205 3645 7chr1 188228813 188229192 - chr2 1125908 1125 - chr5 15486 1548 - 55 9089 383 6840 8chr1 188687834 188688019 - chr2 1125939 1125 - chr5 17153 1715 - 39 9403 526 3865 5chr1 189966942 189967297 + chr2 1134129 1134 + chr5 17154 1715 - 60 1324 181 4291 0chr1 191868755 191869046 + chr2 1156137 1156 - chr5 18134 1813 - 18 1414 263 4463 9chr1 192227646 192227894 + chr2 1159342 1159 + chr5 18905 1890 - 86 3469 734 5916 7chr1 192228206 192228303 + chr2 1170873 1170 - chr5 19067 1906 +11 8748 937 8104 2chr1 192837761 192838046 + chr2 1191772 1191 + chr5 19101 1910 - 92 7753 840 2140 6chr1 192871487 192871556 - chr2 1194907 1194 + chr5 19357 1935 - 37 9106 360 75674Attorney Docket No. 60448-717.601chr1 192871945 192872291 - chr2 1207134 1207 - chr5 19357 1935 - 70 1353 962 8153 5chr1 192908188 192908643 - chr2 1207139 1207 - chr5 21160 2116 +94 1432 450 0765 8chr1 193451038 193451276 - chr2 1208138 1208 - chr5 21633 2163 - 71 1428 753 3976 7chr1 193451683 193451818 - chr2 1208925 1208 + chr5 21714 2171 +77 9293 811 5074 0chr1 193625189 193625489 - chr2 1219958 1219 - chr5 23274 2327 - 81 9614 520 4960 2chr1 194503147 194503360 + chr2 1220988 1220 + chr5 23650 2365 +80 9924 074 0422 4chr1 194503735 194503916 + chr2 1227294 1227 + chr5 25244 2524 +57 2965 368 4676 3chr1 196605202 196605444 - chr2 1228149 1228 - chr5 25406 2540 +45 1507 089 6311 8chr1 199728185 199728351 + chr2 1228156 1228 - chr5 25761 2576 - 83 1596 417 1543 6chr1 201727580 201727920 - chr2 1228952 1228 + chr5 25761 2576 - 19 9534 591 1695 8chr1 205474764 205474892 + chr2 1228977 1228 + chr5 27057 2705 - 63 9819 851 8223 6chr1 205475267 205475333 + chr2 1241542 1241 - chr5 28589 2858 - 55 5438 416 9507 5chr1 205475517 205475775 + chr2 1242354 1242 + chr5 29501 2950 +60 3571 018 1385 4chr1 205476435 205476477 + chr2 1248901 1248 + chr5 30551 3055 - 38 9058 156 1538 0chr1 207146612 207147056 - chr2 1251677 1251 + chr5 30569 3057 - 74 6790 563 0085 5chr1 207154723 207155161 - chr2 1255425 1255 - chr5 31670 3167 - 55 4268 721 1034 8chr1 207187620 207187826 + chr2 1255427 1255 - chr5 32221 3222 +26 4283 220 1518 7chr1 207203014 207203289 - chr2 1268583 1268 + chr5 32494 3249 - 31 5874 958 5430 3chr1 207203618 207203813 - chr2 1282507 1282 - chr5 32654 3265 - 31 5091 435 4707 4chr1 207437491 207437833 - chr2 1285279 1285 + chr5 33623 3362 +89 2819 317 3449 2chr1 208864631 208865053 + chr2 1285284 1285 + chr5 33655 3365 +24 2854 230 5602 6chr1 212244509 212244911 + chr2 1289977 1289 - chr5 33922 3392 - 16 9778 562 3055 9chr1 213484716 213484859 - chr2 1289978 1289 - chr5 34449 3444 - 55 9790 664 99353Attorney Docket No. 60448-717.601chr1 213485166 213485380 - chr2 1289984 1289 - chr5 34591 3459 - 09 9843 482 1922 8chr1 214884673 214884917 - chr2 1300474 1300 - chr5 34758 3475 - 09 4748 296 8352 9chr1 216987675 216988120 + chr2 1300474 1300 - chr5 34758 3475 - 80 4778 900 8978 7chr1 218929542 218929846 - chr2 1303748 1303 + chr5 35244 3524 - 05 7504 803 4870 4chr1 219788027 219788314 - chr2 1304382 1304 - chr5 35244 3524 - 14 3829 870 5127 4chr1 220474776 220474850 + chr2 1304382 1304 - chr5 35361 3536 - 85 3859 668 2044 2chr1 220476260 220476470 + chr2 1306829 1306 + chr5 35404 3540 +23 8323 941 5291 0chr1 221137568 221138035 + chr2 1306832 1306 + chr5 35425 3542 - 21 8330 200 5406 1chr1 221450152 221450354 - chr2 1307489 1307 + chr5 36159 3615 +38 4928 446 9847 9chr1 221852151 221852510 - chr2 1312896 1312 + chr5 36444 3644 +21 8992 421 4825 8chr1 221852825 221852928 - chr2 1312899 1312 + chr5 36458 3645 - 19 8999 878 9322 9chr1 222293099 222293533 + chr2 1320253 1320 + chr5 36530 3653 - 86 2551 825 1106 9chr1 224205911 224206071 - chr2 1327539 1327 + chr5 36531 3653 - 03 5403 183 1229 6chr1 224208287 224208352 - chr2 1327541 1327 + chr5 36725 3672 - 75 5431 316 5388 9chr1 224828493 224828916 - chr2 1329368 1329 - chr5 36748 3674 +45 3690 843 9148 3chr1 225282455 225282742 - chr2 1329369 1329 - chr5 36786 3678 - 66 3729 959 7230 8chr1 226033708 226034079 - chr2 1329694 1329 - chr5 37860 3786 - 18 6950 703 1005 1chr1 229885737 229886129 + chr2 1329695 1329 - chr5 37901 3790 - 00 6968 744 2080 5chr1 229886539 229886612 + chr2 1348443 1348 - chr5 37948 3794 - 49 4477 843 9061 6chr1 232058405 232058659 - chr2 1364944 1364 - chr5 37949 3794 - 03 9452 292 9419 2chr1 232747100 232747470 + chr2 1366913 1366 - chr5 37965 3796 - 61 9156 254 5536 1chr1 232952858 232953272 + chr2 1366916 1366 - chr5 37976 3797 - 20 9177 780 6909 1chr1 233757321 233757791 - chr2 1369924 1369 - chr5 37977 3797 - 13 9273 263 74593Attorney Docket No. 60448-717.601chr1 238395199 238395361 - chr2 1371765 1371 + chr5 38282 3828 - 72 7697 221 2609 3chr1 238395657 238395732 - chr2 1374642 1374 - chr5 38290 3829 - 92 6469 065 0125 1chr1 238511989 238512279 + chr2 1377971 1377 + chr5 38290 3829 - 57 9760 165 0344 4chr1 238512318 238512392 + chr2 1381787 1381 - chr5 38748 3874 - 53 7912 622 8998 8chr1 238712134 238712461 - chr2 1384864 1384 + chr5 39115 3911 +07 8669 837 6211 9chr1 240587885 240588386 + chr2 1386273 1386 + chr5 40287 4028 +66 2767 430 7853 2chr1 244087762 244088181 + chr2 1398848 1398 + chr5 40399 4039 - 35 8521 638 9694 2chr1 245108929 245109205 - chr2 1404001 1404 + chr5 40400 4040 - 22 0056 060 0167 3chr1 245434494 245434939 + chr2 1410896 1410 - chr5 40400 4040 - 00 8990 283 0597 0chr1 246425556 246425790 + chr2 1412522 1412 + chr5 40907 4090 +73 5231 143 7383 7chr1 246978487 246978574 - chr2 1434478 1434 - chr5 40907 4090 +93 4807 709 7959 8chr1 248247461 248247714 - chr2 1451598 1451 - chr5 40983 4098 - 05 6025 214 3272 0chr10 778314 778392 + chr2 1460271 1460 - chr5 41004 4100 - 92 2741 027 4274 3chr10 778397 778466 + chr2 1464167 1464 - chr5 41243 4124 +70 1689 631 4090 7chr10 778471 778544 + chr2 1466226 1466 + chr5 41449 4144 - 32 2300 501 9770 7chr10 1160900 1161033 + chr2 1472895 1472 + chr5 42311 4231 +56 9002 446 1630 5chr10 1946490 1946820 + chr2 1473830 1473 + chr5 43256 4325 +33 8323 553 6983 0chr10 2094290 2094433 - chr2 1481619 1481 + chr5 44192 4419 - 68 6205 816 2853 9chr10 2869270 2869437 - chr2 1481620 1481 + chr5 44735 4473 - 92 6238 727 5970 8chr10 2869539 2869711 - chr2 1489156 1489 - chr5 45075 4507 +80 1609 806 6215 9chr10 3020658 3020902 + chr2 1489161 1489 - chr5 45076 4507 - 00 1620 998 7095 1chr10 7075833 7076263 + chr2 1492891 1492 + chr5 50548 5054 +46 8925 389 8533 8chr10 7458412 7458752 + chr2 1496228 1496 + chr5 50548 5054 +51 2332 627 87270Attorney Docket No. 60448-717.601chr10 9502327 9502657 + chr2 1497490 1497 + chr5 50553 5055 - 44 4925 492 3956 1chr10 9503292 9503435 + chr2 1517564 1517 + chr5 51813 5181 - 82 5666 723 3872 6chr10 9807022 9807313 - chr2 1530467 1530 + chr5 51813 5181 - 34 4681 904 3965 5chr10 10092607 10092902 - chr2 1531196 1531 + chr5 52481 5248 +70 2002 170 1592 5chr10 10938662 10938706 - chr2 1538255 1538 + chr5 52594 5259 - 10 2560 621 4705 8chr10 14304706 14305097 + chr2 1538256 1538 + chr5 52594 5259 - 54 2587 999 5084 9chr10 14650961 14651138 + chr2 1538264 1538 + chr5 52857 5285 +73 2661 795 8013 2chr10 14655614 14655803 - chr2 1544244 1544 + chr5 54706 5470 +91 2487 759 7201 6chr10 14727372 14727750 + chr2 1546228 1546 + chr5 54885 5488 +61 2331 776 6083 4chr10 14973257 14973486 + chr2 1546491 1546 + chr5 54929 5492 - 06 4957 239 9374 8chr10 15027150 15027409 + chr2 1559528 1559 - chr5 54929 5493 - 55 5331 672 0015 1chr10 15618984 15619276 + chr2 1560924 1560 - chr5 55042 5504 - 43 9292 202 2546 4chr10 17279736 17279854 - chr2 1584757 1584 + chr5 55059 5505 - 80 7587 363 9821 9chr10 17425232 17425286 - chr2 1600578 1600 + chr5 56234 5623 +84 5818 172 4446 4chr10 17425771 17425838 - chr2 1605362 1605 - chr5 56337 5633 +57 3668 229 7491 6chr10 17426345 17426685 - chr2 1607409 1607 + chr5 56422 5642 +08 4098 809 3254 3chr10 17816253 17816714 - chr2 1607497 1607 + chr5 56466 5646 - 43 5011 188 6639 0chr10 18835339 18835352 + chr2 1607502 1607 - chr5 56606 5660 - 68 5036 167 6493 4chr10 18835712 18835927 + chr2 1632881 1632 - chr5 56606 5660 - 01 8815 803 6944 6chr10 18835971 18836102 + chr2 1632884 1632 - chr5 56705 5670 +65 8873 045 5498 1chr10 18954549 18954685 + chr2 1638097 1638 + chr5 56805 5680 - 15 1015 524 5766 0chr10 18954754 18954897 + chr2 1640306 1640 - chr5 56805 5680 - 52 3089 968 6161 5chr10 20064937 20065132 + chr2 1640309 1640 - chr5 56963 5696 - 56 3107 566 39116Attorney Docket No. 60448-717.601chr10 20314413 20314686 - chr2 1667622 1667 - chr5 57427 5742 - 93 6253 668 7951 5chr10 20563423 20563587 + chr2 1668612 1668 - chr5 57746 5774 +72 6151 621 7010 0chr10 21204003 21204250 - chr2 1673165 1673 + chr5 57798 5779 +84 1688 331 8444 5chr10 21204668 21204860 - chr2 1701511 1701 + chr5 57798 5779 +48 5122 461 8685 8chr10 21265515 21265700 - chr2 1708801 1708 + chr5 57948 5794 +71 8039 669 9094 3chr10 21265914 21266048 - chr2 1728108 1728 - chr5 57995 5799 +79 1119 414 5841 8chr10 21275356 21275614 + chr2 1728849 1728 + chr5 58213 5821 +26 8539 134 3602 4chr10 22173805 22174159 - chr2 1737878 1737 + chr5 58816 5881 - 71 8830 152 6598 0chr10 25368042 25368281 + chr2 1741407 1741 + chr5 59299 5929 +62 4084 159 9532 5chr10 29773388 29773821 - chr2 1747670 1747 + chr5 59369 5936 - 15 6731 395 9704 2chr10 31195234 31195588 + chr2 1805958 1805 - chr5 60220 6022 - 78 9596 009 0294 5chr10 31210790 31211013 + chr2 1805963 1805 - chr5 60833 6083 +39 9638 412 3568 9chr10 31644023 31644067 - chr2 1805972 1805 - chr5 61136 6113 - 46 9738 580 6902 6chr10 31644430 31644630 - chr2 1806125 1806 - chr5 61602 6160 +97 1278 003 2482 7chr10 32178921 32178987 - chr2 1807813 1807 - chr5 61971 6197 +99 8171 375 1710 4chr10 32179550 32179719 - chr2 1817015 1817 - chr5 61974 6197 - 40 0194 074 4218 7chr10 34307221 34307417 - chr2 1817174 1817 - chr5 62938 6293 - 88 1794 264 8691 3chr10 36497860 36498214 - chr2 1822976 1822 + chr5 63248 6324 +14 9775 924 9301 9chr10 36498512 36498569 - chr2 1822977 1822 + chr5 63580 6358 - 86 9794 967 1053 0chr10 37450790 37451140 + chr2 1823021 1823 + chr5 63581 6358 - 34 0230 094 1378 4chr10 42183381 42183650 - chr2 1823049 1823 + chr5 63843 6384 - 62 0525 762 4196 2chr10 43107051 43107190 + chr2 1834412 1834 - chr5 63996 6399 +44 4161 242 6657 4chr10 43658413 43658666 + chr2 1839574 1839 + chr5 66319 6631 - 14 5760 347 95284Attorney Docket No. 60448-717.601chr10 45811675 45811823 - chr2 1841291 1841 + chr5 67714 6771 - 36 2929 062 4500 6chr10 48554478 48554888 + chr2 1848430 1848 + chr5 67897 6789 - 39 4323 025 7141 2chr10 48727882 48728289 + chr2 1848461 1848 + chr5 67897 6789 - 26 4625 594 7679 3chr10 49068684 49068842 - chr2 1849794 1849 + chr5 68796 6879 +77 7984 502 6756 6chr10 51876611 51877053 + chr2 1849808 1849 + chr5 68945 6894 - 85 8097 799 6225 2chr10 53357500 53357687 - chr2 1849815 1849 + chr5 71815 7181 - 15 8175 204 5686 5chr10 54065247 54065481 + chr2 1852776 1852 - chr5 71995 7199 - 76 7812 383 5537 2chr10 55471943 55472231 + chr2 1853072 1853 + chr5 71995 7199 - 17 0758 561 5747 2chr10 55714797 55715209 - chr2 1854607 1854 - chr5 72539 7253 - 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chr2 1935628 1935 - chr5 75916 7591 +73 6300 794 7197 5chr10 62470103 62470521 - chr2 1935633 1935 - chr5 75953 7595 +64 6362 546 39739Attorney Docket No. 60448-717.601chr10 62668446 62668902 + chr2 1946917 1946 + chr5 76754 7675 +51 9210 759 5224 8chr10 63017311 63017455 - chr2 1978664 1978 + chr5 76878 7687 +60 6684 385 8626 3chr10 63017533 63017625 - chr2 2002840 2002 + chr5 77915 7791 - 18 8447 409 5715 2chr10 63672398 63672731 - chr2 2011135 2011 - chr5 78554 7855 +30 1369 328 4585 3chr10 64271232 64271529 - chr2 2016955 2016 - chr5 79801 7980 - 04 9560 267 1467 5chr10 64271547 64271939 + chr2 2026711 2026 - chr5 80097 8009 +81 7154 521 7910 8chr10 64611918 64612210 - chr2 2038101 2038 - chr5 80628 8062 +51 1037 424 8605 5chr10 64863724 64864129 - chr2 2038103 2038 - chr5 81396 8139 - 98 1052 625 6707 3chr10 64910312 64910448 + chr2 2039691 2039 + chr5 81397 8139 - 15 6920 231 7308 1chr10 64910506 64910619 + chr2 2040726 2040 - chr5 82149 8214 +08 7289 257 9415 8chr10 64981895 64982207 + chr2 2041024 2041 - chr5 82311 8231 +33 0269 383 1825 2chr10 66279406 66279773 + chr2 2043889 2043 - chr5 82322 8232 +39 8939 932 3389 4chr10 67799901 67799948 - chr2 2044045 2044 - chr5 83465 8346 +29 0492 598 6084 7chr10 67800248 67800558 - chr2 2044739 2044 - chr5 84348 8434 - 34 7414 046 8288 5chr10 69763189 69763412 - chr2 2045011 2045 - chr5 84578 8457 +23 0136 575 8946 5chr10 69764710 69764915 - chr2 2045018 2045 - chr5 84589 8458 +01 0187 690 9842 3chr10 70592473 70592924 - chr2 2055677 2055 - chr5 84905 8490 +46 6804 073 5458 5chr10 70594233 70594508 + chr2 2058995 2059 - chr5 84929 8492 +88 0007 541 9632 8chr10 70594811 70594944 + chr2 2064884 2064 - chr5 84931 8493 - 25 8877 105 1388 1chr10 70899493 70899774 + chr2 2074357 2074 + chr5 85576 8557 +43 3620 351 6494 7chr10 70946239 70946639 - chr2 2085455 2085 + chr5 85576 8557 +26 4597 854 7060 7chr10 71040521 71040730 + chr2 2089744 2089 - chr5 85938 8593 +67 7476 706 8804 6chr10 71076909 71077362 - chr2 2105888 2105 + chr5 85939 8593 +95 8932 110 94579Attorney Docket No. 60448-717.601chr10 71348784 71349083 - chr2 2108824 2108 + chr5 86141 8614 +25 8294 159 1410 5chr10 71378388 71378544 + chr2 2109528 2109 + chr5 87127 8712 +83 5324 025 7135 4chr10 71378735 71378948 + chr2 2116161 2116 + chr5 87127 8712 +92 1642 218 7436 8chr10 71505064 71505282 - chr2 2120304 2120 - chr5 87262 8726 +77 3086 226 2688 7chr10 71505453 71505669 - chr2 2128022 2128 + chr5 88494 8849 +65 0273 663 4768 8chr10 71923165 71923404 - chr2 2128071 2128 + chr5 89716 8971 - 76 0753 154 6244 0chr10 72006801 72007078 + chr2 2137260 2137 + chr5 90435 9043 - 07 2638 943 6388 3chr10 72017003 72017443 - chr2 2140307 2140 + chr5 90715 9071 - 17 3099 113 5508 0chr10 73628963 73629088 + chr2 2140320 2140 + chr5 91425 9142 +26 3219 188 5517 0chr10 73629859 73630040 + chr2 2145090 2145 + chr5 91650 9165 +27 0920 039 0473 0chr10 73890705 73890863 - chr2 2148465 2148 - chr5 94195 9419 +31 4678 896 6343 2chr10 73891445 73891735 - chr2 2156041 2156 - chr5 94992 9499 +38 0444 481 2894 8chr10 74337098 74337523 - chr2 2157779 2157 - chr5 95291 9529 +51 7799 203 1499 7chr10 75063452 75063774 + chr2 2157782 2157 - chr5 97417 9741 +66 7869 950 8316 3chr10 75159483 75159608 + chr2 2165934 2165 + chr5 97761 9776 +60 9377 037 1544 1chr10 75159762 75159912 + chr2 2169165 2169 - chr5 97954 9795 +43 1664 321 4576 1chr10 75260458 75260664 - chr2 2169169 2169 - chr5 97956 9795 +31 1726 583 6797 8chr10 75261160 75261407 - chr2 2172606 2172 + chr5 98174 9817 - 61 6101 037 4180 7chr10 75366632 75367021 + chr2 2175601 2175 - chr5 99431 9943 +29 6030 926 2082 7chr10 75911868 75911985 + chr2 2175988 2175 + chr5 99703 9970 - 22 9915 748 4043 2chr10 75912021 75912283 + chr2 2176362 2176 + chr5 10027 1002 +94 3649 4621 7472 7 1 chr10 76013805 76014027 + chr2 2176366 2176 + chr5 10033 1003 - 09 3674 3658 3381 7 4 chr10 76014322 76014488 + chr2 2193687 2193 - chr5 10061 1006 - 10 6917 8317 18483 8Attorney Docket No. 60448-717.601chr10 76746859 76747154 + chr2 2199316 2199 - chr5 10233 1023 - 44 3175 2729 3298 7 1 chr10 77152342 77152818 - chr2 2209773 2209 - chr5 10246 1024 +90 7786 5240 6553 1 7 chr10 77458621 77458777 - 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chr6 75995 7599 +8 7661 752 5914 chr11 97887821 97887849 + chr20 1547818 1547 - chr6 76190 7619 - 0 8393 306 0391 chr11 97887894 97888129 + chr20 1549141 1549 - chr6 76191 7619 - 3 1888 434 1526 chr11 98949123 98949368 + chr20 1558507 1558 + chr6 76305 7630 +9 5187 413 5826 chr11 98949511 98949673 + chr20 1558549 1558 + chr6 76306 7630 +6 5861 357 6442 chr11 100483420 100483798 + chr20 1580469 1580 + chr6 76557 7655 - 3 5162 191 7266 chr11 101719313 101719683 + chr20 1581414 1581 + chr6 76558 7655 - 8 4635 309 8398 chr11 101752903 101753181 - chr20 1585009 1585 - chr6 76558 7655 - 9 0163 597 8743 chr11 101753258 101753297 - chr20 1585017 1585 - chr6 77034 7703 - 5 0501 063 4470 chr11 101759884 101760069 - chr20 1588037 1588 - chr6 77589 7759 +8 0861 706 0089 chr11 101760413 101760747 - chr20 1588742 1588 + chr6 78871 7887 +7 7656 836 2353Attorney Docket No. 60448-717.601chr11 101761099 101761220 - chr20 1588797 1588 + chr6 80508 8050 - 7 8177 689 9019 chr11 101884732 101884798 - chr20 1592172 1592 - chr6 81595 8159 +2 2180 786 6246 chr11 103638207 103638624 + chr20 1596046 1596 - chr6 82259 8225 +1 0772 410 9581 chr11 104025473 104025587 - chr20 1602350 1602 - chr6 82259 8225 +2 4038 626 9741 chr11 104208012 104208383 - chr20 1617328 1617 - chr6 82787 8278 +9 3372 507 7615 chr11 104656734 104657192 + chr20 1617370 1617 - chr6 83813 8381 - 8 3783 738 4142 chr11 105880956 105881437 - chr20 1620667 1620 - chr6 87972 8797 +0 7112 618 3088 chr11 107211849 107212168 + chr20 1662055 1662 + chr6 88108 8810 +3 0677 744 9090 chr11 109411815 109411955 - chr20 1662069 1662 + chr6 88109 8810 +0 0864 636 9986 chr11 109412238 109412720 + chr20 1662929 1662 - chr6 88194 8819 +3 9693 508 4822 chr11 109441695 109441975 + chr20 1663993 1664 + chr6 88486 8848 +1 0165 497 6908 chr11 109441973 109442080 + chr20 1664753 1664 + chr6 88487 8848 +6 7598 213 7267 chr11 109504713 109505092 - chr20 1665391 1665 + chr6 89198 8919 +3 4188 524 8898 chr11 110776196 110776622 - chr20 1665437 1665 + chr6 90320 9032 +2 4496 843 0969 chr11 111001566 111002031 - 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chr20 1777112 1777 + chr6 12086 1208 - 1 1397 9223 69448 chrl2 1570123 1570442 - chr20 1777599 1777 + chr6 12256 1225 +9 6256 7084 67525 chrl2 5719123 5719382 + chr20 1777706 1777 + chr6 12380 1238 - 8 7164 1296 01597 chrl2 5719757 5719998 + chr20 1779775 1779 - chr6 12384 1238 - 9 7804 9260 49727 chrl2 6128252 6128612 - chr20 1779817 1779 + chr6 12540 1254 +4 8630 3185 03427 chrl2 8313243 8313551 - chr20 1781015 1781 + chr6 12737 1273 - 0 0250 6736 77061 chrl2 8313859 8313968 - chr20 1781043 1781 + chr6 12874 1287 +2 0513 1835 42310 chrl2 10305344 10305704 - chr20 1784127 1784 - chr6 13011 1301 - 8 1523 1085 11488 chrl2 14272013 14272422 - chr20 1786758 1786 - chr6 13023 1302 +5 7968 2304 32448 chrl2 15020801 15021029 - chr20 1788298 1788 + chr6 13135 1313 - 6 3138 3951 54318 chrl2 17778558 17778819 + chr20 1789075 1789 - chr6 13378 1337 +4 0845 3870 83951 chrl2 17974253 17974504 - chr20 1792627 1792 + chr6 13434 1343 - 3 6527 6556 46644 chrl2 18927108 18927367 + chr20 1793327 1793 - chr6 13434 1343 - 8 3376 6702 46879 chrl2 20154806 20155014 + chr20 1801914 1801 + chr6 13510 1351 - 0 9450 4948 05193 chrl2 20360672 20360713 - chr20 1801975 1801 + chr6 13587 1358 - 4 9807 7657 78135 chrl2 22947292 22947726 + chr20 1802557 1802 - chr6 13633 1363 - 6 6018 7562 37903 chrl2 25815224 25815371 + chr20 1803773 1803 + chr6 14001 1400 - 1 7953 6721 17193 chrl2 25815676 25815960 + chr20 1809233 1809 + chr6 14121 1412 - 9 2491 1925 12235 chrl2 25816530 25816577 + chr20 1809279 1809 + chr6 14148 1414 - 4 2899 8304 88615 chrl2 26309749 26309951 + chr20 1840014 1840 - chr6 14166 1416 - 5 0673 5197 65664 chrl2 26774897 26775150 + chr20 1873314 1873 - chr6 14297 1429 +2 3356 0614 70913 chrl2 27111045 27111186 - chr20 1880766 1880 + chr6 14297 1429 +9 7895 1267 71339 chrl2 27195728 27196165 + chr20 1880817 1880 + chr6 14297 1429 +1 8314 2100 72225Attorney Docket No. 60448-717.601chrl2 27398060 27398196 + chr20 1882067 1882 - chr6 14436 1443 +2 0936 0512 60955 chrl2 27628779 27628977 - chr20 1882140 1882 - chr6 14513 1451 +0 1435 8007 38460 chrl2 27859668 27859990 + chr20 1885493 1885 + chr6 14575 1457 +3 5235 3977 54387 chrl2 29460502 29460872 + chr20 1889662 1889 - chr6 14575 1457 +0 6808 6586 56793 chrl2 30764636 30764700 + chr20 1889986 1890 + chr6 14575 1457 +2 0168 7110 57149 chrl2 32031146 32031404 - chr20 1890420 1890 + chr6 14644 1464 - 3 4489 0534 41009 chrl2 39723950 39724247 + chr20 1898519 1898 - chr6 14685 1468 - 0 5597 0513 50978 chrl2 39724411 39724599 + chr20 1899351 1899 + chr6 15236 1523 +1 3736 3607 63952 chrl2 39938803 39939278 + chr20 1909560 1909 + chr6 15236 1523 +8 5751 4329 64435 chrl2 45685238 45685458 + chr20 1911993 1912 - chr6 15342 1534 - 0 0327 6100 26339 chrl2 59513662 59514057 + chr20 1925140 1925 - chr6 15342 1534 - 6 1692 8766 28928 chrl2 59987543 59987961 + chr20 1927800 1927 + chr6 15394 1539 - 8 8460 5368 45502 chrl2 61526104 61526556 + chr20 1927977 1927 - chr6 15423 1542 +4 9923 3708 33926 chrl2 61528757 61529207 + chr20 1928034 1928 - chr6 15423 1542 +6 0449 4208 34483 chrl2 67966581 67967007 - chr20 1928065 1928 - chr6 15432 1543 +5 0815 3068 23609 chrl2 68177150 68177480 - chr20 1929848 1929 - chr6 15452 1545 - 5 8610 5839 26074 chrl2 70166254 70166501 + chr20 1929877 1929 - chr6 15557 1555 - 0 9041 9405 79865 chrl2 72103687 72103846 - chr20 1931787 1931 + chr6 15582 1558 +9 8324 5870 26201 chrl2 72103986 72104132 - chr20 1933465 1933 - chr6 15605 1560 +0 4994 7914 58311 chrl2 72696627 72696916 + chr20 1934440 1934 - chr6 15640 1564 - 6 4809 2133 02596 chrl2 72697221 72697254 + chr20 1934934 1934 + chr6 15644 1564 +9 9802 0284 40724 chrl2 72715268 72715666 + chr20 1935979 1936 - chr6 15737 1573 +4 0062 5415 75544 chrl2 73337596 73338064 - chr20 1937102 1937 - chr6 15737 1573 +7 1379 6076 76232Attorney Docket No. 60448-717.601chrl2 76888885 76889216 - chr20 1937479 1937 + chr6 15942 1594 - 3 5178 1517 21613 chrl2 77578314 77578540 + chr20 1940161 1940 + chr6 15991 1599 - 0 2056 5671 15810 chrl2 78240330 78240501 - chr20 1942149 1942 - chr6 16491 1649 - 2 1587 4747 14825 chrl2 80646472 80646691 - chr20 1942192 1942 - chr6 16502 1650 - 6 2100 4517 24893 chrl2 82151090 82151459 - chr20 1944541 1944 - chr6 16699 1669 - 8 5847 2673 92940 chrl2 85712444 85712911 + chr20 1945537 1945 + chr6 16710 1671 - 7 5828 2303 02631 chrl2 86447990 86448368 + chr20 1947947 1947 - chr6 16876 1687 - 4 9779 6924 67020 chrl2 86750538 86750871 chr20 1950546 1950 chr6 41886 4189 +1 5852 GLO 19 02900250v2_altchrl2 88664267 88664586 + chr20 1951091 1951 + chr6 17945 1794 +0 1113 GLO 64 8150025lv2_altchrl2 90421521 90421669 chr20 1951113 1951 + chr6 23209 23218 1262 GLO 27 2730025lv2_altchrl2 90520398 90520693 chr20 1951417 1951 + chr6 23531 2353 +8 4381 GLO 17 3030025lv2_altchrl2 92294608 92295019 + chr20 1952384 1952 + chr6 26142 26148 4253 GLO 79 3410025lv2_altchrl2 92584766 92584875 + chr20 1952531 1952 chr6 33992 33998 5640 GLO 37 6440025lv2_altchrl2 96543203 96543407 chr20 1957191 1957 chr6 42959 4296 +0 2055 GLO 90 4040025lv2_altchrl2 98218661 98219066 + chr20 1957237 1957 chr6 15707 1570 +0 2676 GLO 31 98200252v2_altchrl2 98219616 98219667 + chr20 1958909 1958 chr6 20974 20973 9552 GLO 49 79500252v2_altAttorney Docket No. 60448-717.601chrl2 100679944 100680297 + chr20 1961052 1961 chr6 21296 2129 +9 0987 GLO 24 81000252v2_altchrl2 101502173 101502555 + chr20 1964693 1964 + chr6 23912 23913 7358 GLO 42 30400252v2_altchrl2 101556216 101556400 chr20 1970894 1970 chr6 31695 31694 9254 GLO 89 99600252v2_altchrl2 102803147 102803446 + chr20 1978355 1978 chr6 41273 4127 +7 4001 GLO 15 72900252v2_altchrl2 102803918 102804077 + chr20 1980516 1980 chr6 16251 1625 +9 5384 GLO 14 36500253v2_altchrl2 102821393 102821817 chr20 1981113 1981 chr6 21514 21517 1567 GLO 32 77800253v2_altchrl2 103554450 103554517 chr20 1985985 1986 chr6 21835 2183 +3 0231 GLO 85 77100253v2_altchrl2 103554921 103555072 chr20 1986333 1986 + chr6 24424 24422 3738 GLO 12 47400253v2_altchrl2 103555737 103555844 chr20 1987139 1987 chr6 32270 32276 1482 GLO 25 43200253v2_altchrl2 103555898 103556054 chr20 1987455 1987 + chr6 43031 4303 +1 4705 GLO 44 55800253v2_altchrl2 103557475 103557812 + chr20 1991512 1991 chr6 21852 21854 5545 GLO 68 61400254v2_altchrl2 103623020 103623259 chr20 1998268 1998 + chr6 22174 2217 +9 3088 GLO 97 68300254v2_altchrl2 105267179 105267312 chr20 2010197 2010 + chr6 24760 24769 2146 GLO 24 08600254v2_altchrl2 105267643 105267767 chr20 2010216 2010 + chr6 32638 32643 2279 GLO 96 3030025Attorney Docket No. 60448-717.6014v2_altchrl2 105411664 105412107 chr20 2010229 2010 + chr6 41828 4183 +2 2483 GLO 22 23200254v2_altchrl2 105746392 105746835 + chr20 2010269 2010 + chr6 15699 1570 +0 2811 GLO 62 21300255v2_altchrl2 105748509 105748809 + chr20 2016083 2016 + chr6 20962 20964 1121 GLO 92 63800255v2_altchrl2 106021593 106021785 + chr20 2073695 2073 chr6 21285 2128 +0 7416 GLO 16 70200255v2_altchrl2 106205186 106205625 chr20 2074556 2074 chr6 23899 23896 5778 GLO 13 97500255v2_altchrl2 107428341 107428743 + chr20 2077128 2077 + chr6 31777 31783 1412 GLO 84 19100255v2_altchrl2 107433624 107433764 chr20 2077334 2077 + chr6 40780 4078 +7 3633 GLO 78 49200255v2_altchrl2 107434121 107434411 chr20 2080002 2080 chr6 16133 1613 +8 0248 GLO 45 59600256v2_altchrl2 108048100 108048530 chr20 2080470 2080 chr6 32230 32239 5011 GLO 48 45500256v2_altchrl2 108055936 108056393 + chr20 2082681 2082 chr6 42830 4283 +7 7257 GLO 08 41800256v2_altchrl2 108112636 108112928 chr20 2083313 2083 + chr6 37867 3810 +3 3393 KI27 10800vl altchrl2 108189236 108189515 chr20 2090441 2090 chr6 10805 1083 +0 4723 KI27 3 070800vl altchrl2 108216545 108216864 - chr20 2091476 2091 - chr7 15882 1588 - 2 5258 39 328 chrl2 108386076 108386531 - chr20 2092113 2092 - chr7 15887 1588 -6 1178 92 945Attorney Docket No. 60448-717.601chrl2 108388378 108388812 + chr20 2092621 2092 - chr7 28750 2875 - 6 6298 11 118 chrl2 108452192 108452644 - chr20 2092683 2092 - chr7 29969 2997 +6 6983 14 177 chrl2 108475587 108475998 + chr20 2095146 2095 + chr7 30642 3064 +9 1883 05 315 chrl2 108921350 108921763 - chr20 2099095 2099 - chr7 30643 3064 +3 1003 30 483 chrl2 108949731 108949913 + chr20 2099135 2099 - chr7 30661 3066 - 2 1464 28 227 chrl2 108971582 108971756 - chr20 2099163 2099 - chr7 30696 3069 +2 1746 05 966 chrl2 109645934 109646336 - chr20 2101618 2101 + chr7 30715 3071 +2 6479 05 617 chrl2 110080122 110080265 + chr20 2104408 2104 - chr7 30995 3099 - 1 4440 91 726 chrl2 110080550 110080661 + chr20 2104650 2104 + chr7 31703 3170 +1 6930 28 565 chrl2 110766798 110766964 + chr20 2105251 2105 - chr7 38859 3886 - 5 2979 38 358 chrl2 110767219 110767417 + chr20 2109571 2109 + chr7 39347 3935 - 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chr7 33978 3397 - 9 9478 406 8639 chrl2 117372911 117373107 + chr20 2280063 2280 + chr7 33978 3397 - 0 0739 985 9072 chrl2 117559831 117559953 + chr20 2283718 2283 + chr7 35753 3575 +1 7620 230 3534 chrl2 117563730 117564001 + chr20 2288069 2288 - chr7 35912 3591 - 7 1040 637 2721 chrl2 117748772 117749128 - chr20 2289283 2289 + chr7 38282 3828 +2 2962 092 2218 chrl2 118433664 118433862 - chr20 2289973 2290 - chr7 38504 3850 - 8 0112 367 4839 chrl2 118435158 118435299 - chr20 2290592 2290 + chr7 38677 3867 -4 6340 561 7946Attorney Docket No. 60448-717.601chrl2 118512349 118512395 - chr20 2290854 2290 + chr7 41851 4185 +1 8969 704 2141 chrl2 118512690 118513076 - chr20 2292072 2292 - chr7 42551 4255 - 0 0889 742 1959 chrl2 118519585 118519979 + chr20 2293868 2293 - chr7 42723 4272 +7 9069 583 3903 chrl2 118520275 118520314 + chr20 2300118 2300 + chr7 42739 4273 - 1 1635 008 9094 chrl2 118636194 118636529 + chr20 2307433 2307 + chr7 42739 4273 - 7 4553 537 9854 chrl2 118636957 118637036 + chr20 2308723 2308 - chr7 44542 4454 - 7 7435 566 2846 chrl2 118723533 118723768 - chr20 2309475 2309 - chr7 45425 4542 +1 4849 489 5750 chrl2 118724238 118724402 - chr20 2316655 2316 - chr7 45907 4590 - 3 6882 229 7361 chrl2 118753774 118754123 - chr20 2324576 2324 + chr7 46790 4679 - 1 5935 560 0666 chrl2 118788750 118788938 + chr20 2328255 2328 - chr7 46818 4681 - 1 2728 061 8370 chrl2 118789146 118789386 + chr20 2333393 2333 + chr7 46838 4683 +3 3999 654 8950 chrl2 118832977 118833379 + chr20 2334152 2334 - chr7 48694 4869 - 1 1811 624 5007 chrl2 119083394 119083672 + chr20 2334465 2334 + chr7 48699 4870 - 0 4930 650 0095 chrl2 119138428 119138742 + chr20 2344915 2344 + chr7 48762 4876 +4 9369 483 2649 chrl2 119276077 119276456 - chr20 2354313 2354 + chr7 49277 4927 - 6 3486 087 7184 chrl2 119289639 119289669 - chr20 2355099 2355 - chr7 51000 5100 +8 1089 891 1202 chrl2 119290040 119290094 - chr20 2367146 2367 - chr7 51001 5100 +4 1669 648 1811 chrl2 119290445 119290772 - chr20 2371342 2371 - chr7 52378 5237 +4 3623 167 8235 chrl2 119328124 119328478 - chr20 2372675 2372 - chr7 53469 5346 +7 6961 851 9945 chrl2 119389042 119389246 + chr20 2372703 2372 - chr7 54270 5427 - 2 7112 519 0802 chrl2 119389458 119389610 + chr20 2378548 2378 - chr7 54576 5457 - 9 5688 009 6424 chrl2 119661691 119661883 - chr20 2380257 2380 - chr7 56506 5650 +1 2775 117 6227 chrl2 119662511 119662731 - chr20 2380284 2380 - chr7 57240 5724 +6 2914 625 1079 chrl2 119942077 119942208 - chr20 2394495 2394 - chr7 57862 5786 +5 5163 301 2420 chrl2 119942488 119942535 - chr20 2394524 2394 - chr7 67402 6740 +0 5322 199 2543 chrl2 119945783 119946004 + chr20 2401906 2401 + chr7 67402 6740 +1 9296 894 2969 chrl2 119946313 119946571 + chr20 2402192 2402 + chr7 68240 6824 - 4 2020 955 1122 chrl2 121026376 121026569 - chr20 2403587 2403 - chr7 68241 6824 - 0 6273 516 1616 chrl2 121026869 121027081 - chr20 2404982 2405 + chr7 68381 6838 +2 0106 723 1818 chrl2 121032428 121032738 + chr20 2414443 2414 + chr7 68382 6838 +6 4729 009 2141 chrl2 121128371 121128480 - chr20 2415205 2415 + chr7 68624 6862 +8 2218 619 4984 chrl2 121128755 121128917 - chr20 2425595 2425 - chr7 68626 6862 +3 6425 095 6275 chrl2 121273599 121273886 + chr20 2426217 2426 + chr7 69553 6955 +9 2492 297 3684 chrl2 121755595 121756006 - chr20 2431865 2431 - chr7 70216 7021 +7 9035 422 6877Attorney Docket No. 60448-717.601chrl2 122942966 122943392 + chr20 2432048 2432 - chr7 71386 7138 - 5 0914 947 7186 chrl2 124085676 124085843 + chr20 2432565 2432 - chr7 71387 7138 - 7 5961 302 7346 chrl2 124121636 124121850 + chr20 2436235 2436 + chr7 71387 7138 - 7 2775 621 7753 chrl2 124123011 124123250 + chr20 2441014 2441 - chr7 71387 7138 +7 0492 834 7929 chrl2 124231492 124231716 - chr20 2450182 2450 + chr7 71390 7139 - 4 2249 808 0966 chrl2 124662274 124662388 - chr20 2450696 2450 - chr7 71392 7139 - 7 7081 140 2417 chrl2 125227095 125227179 + chr20 2453354 2453 - chr7 73123 7312 +7 3783 201 3451 chrl2 125227851 125228113 + chr20 2457408 2457 + chr7 73124 7312 +0 4162 082 4172 chrl2 125962338 125962419 - chr20 2465262 2465 + chr7 73311 7331 +3 2847 739 1890 chrl2 125962791 125962850 - chr20 2465286 2465 + chr7 73859 7385 +3 3044 372 9543 chrl2 125963100 125963427 - chr20 2468532 2468 + chr7 74423 7442 - 1 5400 249 3364 chrl2 126395557 126395733 - chr20 2473713 2473 + chr7 74932 7493 +0 7229 022 2272 chrl2 126926224 126926486 - chr20 2473791 2473 - chr7 74932 7493 +8 8254 877 2967 chrl2 127177568 127177862 - chr20 2478632 2478 + chr7 75268 7526 - 6 6404 506 8596 chrl2 127209937 127210074 + chr20 2478649 2478 + chr7 75269 7526 - 1 6679 229 9388 chrl2 127235924 127236151 + chr20 2478692 2478 + chr7 75686 7568 - 7 7047 487 6608 chrl2 127556463 127556611 - chr20 2502456 2502 + chr7 75764 7576 +5 4667 744 4864 chrl2 128700862 128701239 - chr20 2508556 2508 + chr7 75765 7576 +0 5864 166 5420 chrl2 128720043 128720245 + chr20 2509121 2509 + chr7 75775 7577 - 6 1327 366 5781 chrl2 129212950 129213134 - chr20 2512050 2512 - chr7 75801 7580 - 5 0873 238 1348 chrl2 129213940 129214205 - chr20 2513073 2513 + chr7 76671 7667 +5 0912 113 1283 chrl2 129485042 129485487 - chr20 2514709 2514 + chr7 76671 7667 +1 7436 300 1388 chrl2 129485925 129486371 + chr20 2517623 2517 + chr7 76671 7667 +6 6293 403 1505 chrl2 129570386 129570655 - chr20 2517895 2517 + chr7 76683 7668 - 0 9017 047 3368 chrl2 130623620 130624070 + chr20 2519059 2519 - chr7 76771 7677 +6 0762 575 1866 chrl2 131489655 131490000 - chr20 2561866 2561 + chr7 76942 7694 - 0 8940 911 3261 chrl2 133050044 133050501 - chr20 2595419 2595 + chr7 77237 7723 - 3 4332 095 7561 chrl2 174402 174578 chr20 2960600 2960 chr7 82054 8205 + GL38 0 6139 327 4648 3551v1 altchrl2 116526 116816 chr20 3025058 3025 + chr7 82057 8205 + GL87 6 0725 990 8328 7875v1 altchrl3 18740734 18741039 - chr20 3061261 3061 - chr7 82149 8214 - 5 2695 297 9539 chrl3 18877736 18877969 + chr20 3061268 3061 - chr7 82150 8215 -6 2992 011 0050Attorney Docket No. 60448-717.601chrl3 22288504 22288974 - chr20 3165379 3165 + chr7 84840 8484 +8 4119 503 0833 chrl3 24142986 24143105 - chr20 3189051 3189 - chr7 85308 8530 +1 0984 121 8537 chrl3 26772754 26772880 + chr20 3204972 3205 + chr7 86830 8683 +9 0060 028 0460 chrl3 26773094 26773151 + chr20 3205866 3205 - chr7 87234 8723 +9 9138 674 5112 chrl3 26773540 26773697 + chr20 3315120 3315 - chr7 88272 8827 +5 1561 094 2497 chrl3 28630418 28630555 - chr20 3328721 3328 - chr7 88332 8833 +4 7371 455 2643 chrl3 28630868 28631025 - chr20 3328802 3328 - chr7 88333 8833 +8 8215 192 3336 chrl3 31484265 31484345 - chr20 3331127 3331 + chr7 89240 8924 +3 1423 977 1455 chrl3 32878816 32879298 + chr20 3331164 3331 + chr7 91561 9156 - 4 1787 116 1215 chrl3 33820215 33820690 + chr20 3332854 3332 - chr7 91561 9156 - 2 8632 567 1910 chrl3 33970540 33970994 - chr20 3340456 3340 - chr7 93614 9361 +3 4604 834 5021 chrl3 34618762 34619116 - chr20 3340489 3340 - chr7 93756 9375 - 8 5081 429 6546 chrl3 37140173 37140269 + chr20 3370352 3370 - chr7 96679 9668 +2 3958 877 0334 chrl3 37141138 37141487 + chr20 3392977 3393 + chr7 97643 9764 - 5 0153 609 3801 chrl3 37147441 37147742 + chr20 3398301 3398 - chr7 97646 9764 - 2 3377 622 6720 chrl3 37148112 37148285 + chr20 3513292 3513 - chr7 97776 9777 - 5 3398 799 7223 chrl3 37376098 37376399 + chr20 3627789 3627 + chr7 98482 9848 +6 8002 952 3062 chrl3 37376844 37377037 + chr20 3640814 3640 - chr7 98483 9848 +6 8509 077 3274 chrl3 38477759 38478082 + chr20 3641017 3641 + chr7 98483 9848 +9 0439 659 3750 chrl3 38961120 38961400 + chr20 3641085 3641 + chr7 98704 9870 +1 0972 249 4525 chrl3 39177333 39177457 - chr20 3641128 3641 + chr7 98705 9870 +9 1342 404 5552 chrl3 39177461 39177864 - chr20 3679584 3679 + chr7 98806 9880 +6 6143 227 6365 chrl3 40377675 40377859 + chr20 3694302 3694 - chr7 98806 9880 +9 3213 586 6879 chrl3 41402809 41403100 + chr20 3755881 3755 + chr7 99265 9926 +0 9255 873 6061 chrl3 43779218 43779373 - chr20 3760676 3760 + chr7 99266 9926 +9 6841 184 6356 chrl3 44157042 44157418 - chr20 3761047 3761 + chr7 99489 9948 +9 0799 414 9664 chrl3 44825301 44825677 - chr20 3768258 3768 - chr7 10028 1002 - 2 2952 6544 86619 chrl3 45168223 45168485 + chr20 3768326 3768 - chr7 10028 1002 - 5 3354 7212 87462 chrl3 45818030 45818330 + chr20 3793232 3793 + chr7 10153 1015 - 6 2771 3575 33816 chrl3 45884372 45884520 - chr20 3793295 3793 - chr7 10393 1039 - 7 3130 2712 32979 chrl3 46756978 46757166 - chr20 3797121 3797 - chr7 10488 1048 - 2 1442 7266 87715Attorney Docket No. 60448-717.601chrl3 47068963 47069361 - chr20 3797160 3797 - chr7 10623 1062 - 3 1834 3679 34121 chrl3 47822755 47823142 + chr20 3821191 3821 + chr7 10685 1068 +0 2032 2343 52805 chrl3 47826373 47826465 + chr20 3821247 3821 + chr7 10788 1078 +0 2608 4435 84738 chrl3 50706929 50706991 - chr20 3831652 3831 - chr7 10788 1078 +4 6808 5246 85396 chrl3 50708468 50708948 - chr20 3834683 3834 - chr7 10835 1083 +8 7049 0454 50722 chrl3 52338815 52339242 + chr20 3834762 3834 - chr7 10932 1093 - 2 7858 3213 23605 chrl3 52772175 52772628 + chr20 3835120 3835 - chr7 10946 1094 +6 1487 9952 70054 chrl3 52839986 52840364 - chr20 3838017 3838 - chr7 10999 1099 +3 0228 7003 97274 chrl3 53419171 53419251 - chr20 3865108 3865 - chr7 11234 1123 - 1 1551 9892 50308 chrl3 53509862 53510229 - chr20 3865571 3865 - chr7 11367 1136 +8 6011 6166 76680 chrl3 55220842 55221021 + chr20 3865706 3865 - chr7 11603 1160 - 8 7222 6230 36509 chrl3 57875848 57875911 - chr20 3865727 3865 - chr7 11657 1165 - 3 7387 9838 80184 chrl3 57875942 57876227 - chr20 3865770 3865 - chr7 11817 1181 - 3 7791 2868 73231 chrl3 58011484 58011958 - chr20 3870013 3870 + chr7 11946 1194 - 8 0251 6778 66930 chrl3 58360933 58361399 - chr20 3870117 3870 + chr7 11946 1194 - 8 1662 7287 67465 chrl3 59326865 59327246 + chr20 3873583 3873 - chr7 12161 1216 +2 6019 0374 10770 chrl3 59384154 59384539 + chr20 3912513 3912 + chr7 12176 1217 - 7 5314 4743 65028 chrl3 60290367 60290461 - chr20 3912581 3912 + chr7 12206 1220 - 8 6090 8820 68863 chrl3 61789571 61789912 - chr20 3913875 3913 + chr7 12206 1220 - 8 8986 8879 69238 chrl3 62598566 62599015 - chr20 3920078 3920 - chr7 12411 1241 +3 1265 4844 15204 chrl3 62981415 62981687 - chr20 3923748 3923 + chr7 12443 1244 +5 7929 8176 38423 chrl3 63614617 63614826 - chr20 3929321 3929 - chr7 12572 1257 +0 3704 1622 21754 chrl3 69092500 69092774 - chr20 3932337 3932 + chr7 12633 1263 - 2 3580 8369 38672Attorney Docket No. 60448-717.601chrl3 69615896 69616014 - chr20 3933999 3934 + chr7 12672 1267 +7 0402 9185 29553 chrl3 69616063 69616287 - chr20 3935867 3935 + chr7 12725 1272 - 5 8956 6661 57120 chrl3 69618417 69618504 - chr20 3940586 3940 + chr7 12751 1275 - 9 6150 3199 13349 chrl3 69619058 69619444 - chr20 3950472 3950 - chr7 12945 1294 +2 4825 2508 52553 chrl3 70738297 70738485 + chr20 3950517 3950 - chr7 12945 1294 +8 5433 2696 52865 chrl3 70858694 70858819 + chr20 3960489 3960 - chr7 12945 1294 +0 5131 2884 53011 chrl3 70932661 70932913 + chr20 3977295 3977 - chr7 12959 1295 - 4 3412 0976 91318 chrl3 74258801 74259226 - chr20 3983049 3983 - chr7 13095 1309 +0 0752 0067 50107 chrl3 74561569 74561666 + chr20 3987020 3987 - chr7 13100 1310 +7 0700 8035 08305 chrl3 76286973 76287187 + chr20 4005077 4005 - chr7 13183 1318 - 4 1091 1884 32068 chrl3 77308621 77309065 - chr20 4024091 4024 + chr7 13437 1343 - 0 1209 0532 71036 chrl3 77776099 77776383 - chr20 4031697 4031 + chr7 13461 1346 - 3 7298 5814 16276 chrl3 80567199 80567636 - chr20 4038454 4038 + chr7 13493 1349 - 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chr7 14956 1495 +6 7168 4452 64785 chrl3 103608189 103608580 + chr20 4213933 4213 - chr7 14956 1495 +1 9680 5234 65370 chrl3 104303895 104304337 - chr20 4214368 4214 - chr7 14960 1496 +5 4137 0078 00218 chrl3 104307606 104308059 - chr20 4235511 4235 + chr7 15023 1502 +8 5425 7220 37568 chrl3 104395348 104395554 + chr20 4245488 4245 + chr7 15023 1502 +3 5040 7985 38092 chrl3 105169113 105169567 - chr20 4245531 4245 + chr7 15043 1504 - 9 5492 2811 32977 chrl3 106581877 106582108 + chr20 4264528 4264 + chr7 15071 1507 - 8 5568 4966 15400 chrl3 107743005 107743259 + chr20 4268629 4268 + chr7 15138 1513 - 0 6457 2703 82921 chrl3 109379760 109379975 - chr20 4268679 4268 + chr7 15187 1518 - 2 6927 2413 72776Attorney Docket No. 60448-717.601chrl3 109916139 109916397 - chr20 4274858 4274 + chr7 15207 1520 - 0 9007 6317 76753 chrl3 110000980 110001412 - chr20 4315899 4315 - chr7 15373 1537 - 9 9268 1187 31294 chrl3 111912615 111912904 + chr20 4315930 4315 - chr7 15373 1537 - 6 9385 1710 32058 chrl3 111949570 111949758 + chr20 4321108 4321 + chr7 15554 1555 - 8 1556 1938 42097 chrl3 112615515 112615628 - chr20 4321647 4321 - chr7 15556 1555 - 1 6889 7802 67959 chrl3 42384 42689 chr20 4321743 4321 chr7 15613 1561 + KI270 2 7919 5904 3637 840vl 2 altchrl3 185276 185509 + chr20 4322258 4322 chr7 15839 1583 KI270 5 2994 9801 9988 840vl 0 altchrl4 20021103 20021297 + chr20 4325105 4325 + chr7 15929 1592 - 9 1450 3171 93546 chrl4 21650546 21650709 chr20 4325176 4325 + chr7 77295 7737 +0 1815 KI27 40805vl altchrl4 21802081 21802188 + chr20 4328131 4328 + chr7 61322 61769 1740 KI27 20808vl altchrl4 22268884 22268975 + chr20 4331732 4331 chr7 15794 1581 +6 7490 KI27 8 180809vl altchrl4 22269716 22269816 + chr20 4331812 4331 chr7 15813 1582 +1 8351 KI27 5 230809vl altchrl4 23865894 23866222 + chr20 4333961 4333 + chr7 15823 1583 +4 9891 KI27 8 400809vl altchrl4 23866415 23866544 + chr20 4334348 4334 + chr7 16988 17022 3861 KI27 2 030809vl altchrl4 24467463 24467941 - chr20 4334442 4334 + chr8 32291 3233 - 1 4490 5 51 chrl4 26601713 26602030 - chr20 4335013 4335 - chr8 26841 2684 +8 0389 27 242 chrl4 26602029 26602152 + chr20 4338002 4338 + chr8 48782 4878 - 2 0150 38 334 chrl4 27536621 27536963 - chr20 4338751 4338 - chr8 52667 5266 - 6 7856 41 988 chrl4 27601278 27601509 - chr20 4343840 4343 + chr8 53553 5355 +7 8605 98 763Attorney Docket No. 60448-717.601chrl4 28703002 28703324 + chr20 4343906 4343 + chr8 59980 5998 - 3 9350 64 189 chrl4 29066940 29067241 - chr20 4344235 4344 + chr8 81492 8149 +3 2803 80 389 chrl4 29950607 29950879 - chr20 4373605 4373 - chr8 81496 8150 +0 6143 95 003 chrl4 29951246 29951315 - chr20 4373668 4373 - ch...

Claims

Attorney Docket No. 60448-717.601CLAIMS WHAT IS CLAIMED IS:

1. An antisense oligonucleotide molecule modulating an expression level or activity of a transposable element or a transcript transcribed from the transposable element, wherein the transposable element is selected from a group consisting of LTR16, LTR16A, LTR16A1, LTR16A2, LTR16B, LTR16B1, LTR16B2, LTR16C, LTR16D, LTR16D1, LTR16D2, LTR16E1, LTR16E2, ERV3-16A3 LTR, MER39, THE1A, THE1B, THE1C, THE1D, MSTA, MSTA1, MSTB, MSTB1, MSTB2, MSTC, MSTD, MLT1A0, MLT1A1, MLT1C, MLT1D, MLT1E, MLT1E1, MLT1E2, MLT1F, MLT1F1, MLT1F2, MLT1G1, MLT1G3, MLT1H, MLT1H1, MLT1I, MLT1J, MLT1J1, MLT1J2, MLT1K, MLT1L, MLT1M, MLT1N2, MLT10, MLT2A1, MLT2A2, MLT2B1, MLT2B2, MLT2B3, MLT2B4, MLT2B5, MLT2C1, MLT2C2, MLT2D, MLT2E, MLT2F, MLT1A, MLT1B, MLT1E1A, MLT1E3, MLT1G, MLT1H2, MLT1C2, MLTIF-int, MST-int, MLT-int, MLT1H-int, MLT1J-int, THEl-int, HERV16, ERVL-E, HERVL, ERVL-B4, ERV3-16A3 I, LTR33, LTR50, LTR78, LTR41, LTR41B, HERV3-int, LTR13, HERVL18-int, MER66C, MER66D, or LTR19C subfamilies.

2. The antisense oligonucleotide molecule of claim 1, wherein the transposable element comprises a sequence that is at least 70%, at least 80%, at least 90%, or at least 95% identical to at least a fragment of a sequence selected from any one of SEQ ID NOs: 4- 121.

3. The antisense oligonucleotide molecule of claim 1, wherein the transposable element comprises a sequence that is at least 70%, at least 80%, at least 90%, or at least 95% identical to at least a fragment of a sequence selected from any one of SEQ ID NOs: 4, 10, 14, 15, 18, 27-32, and 34-38.

4. The antisense oligonucleotide molecule of any one of the preceding claims, wherein the transposable element comprises a sequence at least 70%, at least 80%, at least 90%, or at least 95% identical to at least a fragment of SEQ ID NO: 4.

5. The antisense oligonucleotide molecule of any one of preceding claims, wherein the transposable element comprises a sequence of SEQ ID NO: 5, SEQ ID NO: 6, or wherein the transposable element or a fragment thereof is located in chr3: 45,818,736-45,818,762 (hg38) or chr3: 45,818,689-45,818,712 (hg38).Attorney Docket No. 60448-717.6016. The antisense oligonucleotide molecule of any one of preceding claims, wherein the antisense oligonucleotide molecule induces or facilitates a change of a state of a cell from a first cellular state to a second cellular state.

7. The antisense oligonucleotide molecule of claim 6, wherein the first cellular state or the second cellular state comprises an extracellular-cellular-matrix synthesizing state, a cytokine-secreting state, an inflammatory state, a cell dividing state, a cell pausing state.

8. The antisense oligonucleotide molecule of any one of preceding claims, wherein the transposable element transcript modulates a functional RNA.

9. The antisense oligonucleotide molecule of claim 8, wherein the functional RNA comprises a messenger RNA (mRNA), a long noncoding RNA (IncRNA), a circular RNA, a small nuclear RNAs (snRNAs), a small nucleolar RNAs (snoRNAs), a microRNA, an X-inactive specific transcript (xist) RNA, or a combination thereof.

10. The antisense oligonucleotide molecule of any one of the preceding claims, wherein the expression level or activity of the transposable element or the transcript transcribed from the transposable element is associated with pulmonary fibrosis.

11. The antisense oligonucleotide molecule of claim 10, wherein the expression level of the transcript transcribed from the transposable element is increased in a cell affected by pulmonary fibrosis compared to a healthy cell.

12. The antisense oligonucleotide molecule of any one of the preceding claims, wherein the antisense oligonucleotide molecule comprises at least 9 consecutive nucleotides with no more than 3 mismatches from SEQ ID NOs: 124-456.

13. The antisense oligonucleotide molecule of any one of the preceding claims, wherein the antisense oligonucleotide molecule comprises a nucleic acid sequence at least 80%, at least 85%, at least 90%, at least 95%, identical to a sequence selected from SEQ ID NOs: 124-456.

14. The antisense oligonucleotide molecule of claim 12 or 13, wherein the antisense oligonucleotide molecule targets or binds to at least one of LTR16C integrant listed in Table 8.Attorney Docket No. 60448-717.60115. The antisense oligonucleotide molecule of any one of claims 12-14, wherein the antisense oligonucleotide molecule is a Gapmer with three consecutive LNAs in a 5 ’-wing region and two consecutive LNAs in a 3 ’-wing region.

16. The antisense oligonucleotide molecule of claim 15, wherein one or more intemucleotide linkage of the antisense oligonucleotide molecule is substituted with a phosphorothioate backbone.

17. The antisense oligonucleotide molecule of claim 16, wherein all intemucleotide linkages of the antisense oligonucleotide molecule are phosphorothioate intemucleotide backbone.

18. A pharmaceutical composition comprising the antisense oligonucleotide molecule of any one of claims 1-17 and a pharmaceutically acceptable salt, excipient, or derivative thereof.

19. A kit comprising the antisense oligonucleotide molecule of any one of claims 1-17 or the pharmaceutical composition of claim 18.

20. A method of preventing, alleviating, or treating pulmonary fibrosis in a subject in need thereof, the method comprising administering to the subject an effective amount of the antisense oligonucleotide molecule of any one of claims 1-17 or the pharmaceutical composition of claim 18.

21. The method of claim 20, wherein the antisense oligonucleotide molecule of any one of claims 1-17 or the pharmaceutical composition of claim 18 reduces expression of a fibrosis-related marker in a fibroblast affected by the pulmonary fibrosis.

22. The method of claim 21, wherein the fibrosis-related marker comprises smooth muscle α actin (ACTA2), alpha 1 chain of collagen type I (COL1A1), alpha 1 chain of collagen type 3 (COL3A1), fibroblast activation protein (FAP), fibronectin 1 (FN1), periostin (POSTN), collagen triple helix repeat containing 1 (CTHRC1), alpha 1 chain of collagen type 10 (COL10A1), matrix metalloproteinase 11 (MMP11), thrombospondin 2 (THBS2), latent transforming growth factor beta binding protein 2 (LTBP2), Integrin-α11 (ITGA11), or a combination thereof.

23. The method of any one of claims 20-22, wherein the antisense oligonucleotide molecule of any one of claims 1-17 or the pharmaceutical composition of claim 18 restores an expression of a set of genes that are aberrantly expressed in idiopathic pulmonary fibrosis (IPF) comparable to a healthy cell.Attorney Docket No. 60448-717.60124. The method of claim 23, wherein the set of genes comprises one or more genes identified in Table 4.

25. A method of reprogramming a myofibroblast into an early fibroblast precursor cell, a cell that is Top2a, Cenpa or ki67 positive, or a proliferating fibroblast, the method comprising contacting the myofibroblast with an effective amount of the antisense oligonucleotide molecule of any one of claims 1-17 or the pharmaceutical composition of claim 18.

26. The method of claim 25, wherein the early fibroblast precursor cell is a mesothelial cell, an early fibroblast cell, a mid fibroblast cell, or a mesenchymal cell.

27. The method of claim 25, wherein the cell that is Top2a, Cenpa or Ki67 positive is a mesenchymal progenitor cell, and optionally wherein the mesenchymal progenitor cell is an epithelial progenitor cell, an endothelial progenitor cell, or a fibroblast progenitor cell.

28. A method of slowing or reversing aging of a pulmonary tissue in a subject, the method comprising administering to the subject an effective amount of the antisense oligonucleotide molecule of any one of claims 1-17 or the pharmaceutical composition of claim 18.

29. The method of claim 20, wherein upregulated proteostasis is observed in the pulmonary tissue, and optionally wherein an expression of Zmpste24 or Lamp2 is increased in the pulmonary tissue.

30. The method of claim 28 or 29, wherein upregulated macro-autophagy is observed in the pulmonary tissue, and optionally wherein the expression of Atg5 or Atg7 is increased in the pulmonary tissue.

31. The method of any one of claims 28-30, wherein a more active telomerase is observed in the pulmonary tissue, and optionally wherein an expression of Tert or Terc is increased in the pulmonary tissue.

32. The method of any one of claims 28-31, wherein an age-related inflammation or an age- related tissue repair capability is improved in the pulmonary tissue.

33. The method of claim 32, wherein more M0 macrophages or fewer profibrotic M2 macrophages are observed in the pulmonary tissue.

34. The method of claim 32 or 33, wherein fewer white blood cells or fewer macrophages are observed in a bronchioalveolar lavage of the subject.

35. The method of any one of claims 32-34, wherein a number of total T cells or activated T cells is decreased in the pulmonary tissue, or a number of immunosuppressive Ctla4- expressing cells is increased in the pulmonary tissue.Attorney Docket No. 60448-717.60136. The method of any one of claims 32-35, wherein a cell-cell communication between a fibroblast and an immune cell (e.g., a T cell, an M0, M1, or M2 macrophage) is decreased in the pulmonary tissue.

37. The method of any one of claims 20-24, and 28-36, wherein the antisense oligonucleotide molecule is delivered by inhalation.

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