Isoxazoline oral compositions for ectoparasite control in livestock animals

A liquid veterinary oral drench composition with isoxazoline compounds and excipients offers effective, long-lasting ectoparasite control for livestock, addressing the limitations of current treatments by ensuring safety and practicality while minimizing environmental contamination.

WO2026115021A1PCT designated stage Publication Date: 2026-06-04INTERVET INT BV +1

Patent Information

Authority / Receiving Office
WO · WO
Patent Type
Applications
Current Assignee / Owner
INTERVET INT BV
Filing Date
2025-11-27
Publication Date
2026-06-04

AI Technical Summary

Technical Problem

Current treatments for ectoparasites in livestock animals, particularly ticks, are labor-intensive, cause stress, have low efficacy, lead to economic losses, and pose risks of environmental contamination and applicator exposure, with a need for safe, effective, and stable oral compositions.

Method used

A liquid veterinary oral drench composition comprising isoxazoline compounds like fluralaner, afoxolaner, or lotilaner, with viscosity agents, surfactants, and suspending agents, forming a ready-to-use aqueous suspension for oral administration.

Benefits of technology

The composition provides fast and long-lasting ectoparasite control with minimal environmental impact, ensuring safety for animals and applicators, and allows for practical administration without complex equipment, with a suitable withholding period for dairy products.

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Abstract

The present invention relates to an oral liquid veterinary pharmaceutical composition comprising an isoxazoline compound selected from the group consisting of fluralaner, afoxolaner, lotilaner, and sarolaner, designed to effectively treat and control ectoparasite infestations in livestock, specifically cattle. The composition is formulated as a ready-to-use aqueous suspension that includes a viscosity agent, surfactant, and suspending agent.
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